passages.id: split_1_test_3144_passage
passages.type: progene_text
passages.text: GnRH induced the alpha - subunit promoter - luciferase reporter approximately 16 - fold , and this induction was completely abolished with mutations in the dual cAMP response elements ( CREs ) or the combined inhibition of GnRH - induced ERK and c-Jun N - terminal kinase .