passages.id: split_1_test_1574_passage
passages.type: progene_text
passages.text: The 9 - fold increase in CAT mRNA levels attained with the - 533 to - 764 bp PAI-1 SRR ligated to a minimal PAI-1 promoter ( i.e. , 162 bp of 5' flanking sequence containing the basal transcription complex ) closely approximated the serum - induced transcriptional activity of a fully responsive ( 1 , 230 bp ) PAI-1 promoter construct as well as the endogenous PAI-1 gene .