passages.id: split_1_test_1945_passage
passages.type: progene_text
passages.text: Taken together , the results suggest that an elevation of intracellular cAMP ( in the absence of antigen ) creates an oxidative environment that oxidizes and inactivates p56 ( lck ) by an H(2)O(2) - dependent , PKA - independent mechanism and inhibits the production of IFN-gamma by an NO , PKA - dependent mechanism .