passages.id: split_1_test_3105_passage
passages.type: progene_text
passages.text: The putative new interleukin ( IL ) - 1 family member IL-1F8 ( IL-1eta , IL-1H2 ) has been shown recently to activate mitogen activated protein kinases ( MAPKs ) , extracellular signal - regulated protein kinase ( ERK1 / 2 ) and c-Jun N - terminal kinase ( JNK ) , and nuclear factor - kappa B ( NFkappa B ) via a mechanism that requires IL-1Rrp2 expression in cell lines .