passages.id: split_1_test_1099_passage
passages.type: progene_text
passages.text: We generated all six full - length mouse cDNAs that result from combinations of these three major splicing events and show that their transfection into cells in culture leads to production of four different approximately 74 kDa full - length ( heart - , skeletal muscle - or brain - specific ) and two C - terminally truncated approximately 68 kDa ( smooth muscle - specific ) isoforms .