passages.id: split_1_test_253_passage
passages.type: progene_text
passages.text: Here , we describe the transient activation of SAPK / JNKs by tumor - like hypoxia , and the concurrent transcriptional activation of MKP-1 , a stress - inducible member of the MAPK phosphatase ( MKP ) family of dual specificity protein - tyrosine phosphatases .