passages.id: split_1_test_3038_passage
passages.type: progene_text
passages.text: In 247 MS patients and 194 controls , single nucleotide polymorphisms ( SNPs ) at position + 869 ( Leu10Pro ) and position + 915 ( Arg25Pro ) in the signaling sequence of the TGFB1 gene were determined , and the distribution of alleles , genotypes , and haplotypes was related to clinical data .