passages.id: split_1_test_1537_passage
passages.type: progene_text
passages.text: The aims of this study were to investigate the effect of the cytokines interleukin-1 beta ( IL-1 beta ) , IL-6 , IL-10 , transforming growth factor - beta 1 ( TGF-beta 1 ) , and hepatocyte growth factor ( HGF ) on expression of cathepsin B and cathepsin L mRNA ( quantitative RT - PCR ) , on protein expression ( ELISA , Western blot ) , and also on enzymatic activity of cathepsins B and L .