passages.id: split_1_test_1655_passage
passages.type: progene_text
passages.text: The generation of this large collection of polymorphic cell surface and soluble variants that exhibit inter - individual variation in expression levels has important implications for the pathogenesis of HIV-1 infection , as well as for the molecular code required to establish complex interactions between antigen - presenting cells and T cells , i.e. the immunological synapse .