passages.id: split_1_test_2013_passage
passages.type: progene_text
passages.text: The findings of the present study suggest that the LPS receptor CD14 , existent in human osteoblastic cells , and IL-6 synthesis in response to LPS probably occur via CD14 , p38 MAPK , and MAP kinase / extracellular - regulated kinase kinase ( MEK ) , leading to the transcriptional activation of AP-1 in human osteoblastic cells .