text: 24269774_19	CONCLUSION: These findings suggest that AD-EFV could ameliorate Ab induced cognitive dysfunction through two underlying mechanisms: AD-EFV enhances the cerebral cholinergic function by increasing the secretion of ACh and enhancing the ChAT activity, and AD-EFV protects the brain neurons from Ab induced apoptosis via activating the p-ERK and Bcl-2 signaling and suppressing the Bax pathways.