diff --git "a/TXT/Usage/train.txt" "b/TXT/Usage/train.txt" new file mode 100644--- /dev/null +++ "b/TXT/Usage/train.txt" @@ -0,0 +1,15337 @@ +CID Question Answer +4114 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option B: It is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration. +Option C: It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. +Option D: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +" C +5284517 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]([C@@H]1CC[C@H]([C@H](O1)O[C@@H]2[C@H]([C@@H]([C@@H]([C@H]([C@H]2O)N(C)C(=O)CN)OC)O)N)N)N +Question about this molecule: What is the right administration information about this molecule? +Option A: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +Option B: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media. +Option C: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +Option D: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +" D +135398748 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option B: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +Option C: It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. +Option D: It is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration. +" D +11273 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CCC(=O)C(=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O +Question about this molecule: What is the right administration information about this molecule? +Option A: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +Option B: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option C: As it has poor oral bioavailability, it had to be administered by (fortnightly) intramuscular injection. +Option D: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +" C +68617 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. +Option B: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +Option C: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option D: It is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. +" A +3083544 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CC1=CC=C(C=C1)OC)NC[C@@H](C2=CC(=C(C=C2)O)NC=O)O +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option B: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media. +Option C: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +Option D: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +" C +4497 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration. +Option B: It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. +Option C: It is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm. +Option D: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +" C +63009 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +Option B: It is administered orally as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. +Option C: It is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. +Option D: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +" B +4173 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CCO)[N+](=O)[O-] +Question about this molecule: What is the right administration information about this molecule? +Option A: As it has poor oral bioavailability, it had to be administered by (fortnightly) intramuscular injection. +Option B: It may be given by mouth in tablets, or as the benzoate in an oral suspension. +Option C: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +Option D: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +" B +68624 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl +Question about this molecule: What is the right administration information about this molecule? +Option A: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +Option B: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option C: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +Option D: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media. +" D +5282242 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\\CC(=O)O)/C3=CSC(=N3)N)C(=O)O +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option B: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +Option C: Ceftibuten is used as the dihydrate to treat urinary-tract and respiratory-tract infections. +Option D: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +" C +3080 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(CS)S)O +Question about this molecule: What is the right administration information about this molecule? +Option A: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease. +Option B: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +Option C: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media. +Option D: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +" B +5462501 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)N[C@@H](CCC2=CC=CC=C2)C(=O)O +Question about this molecule: What is the right administration information about this molecule? +Option A: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. +Option B: As it has poor oral bioavailability, it had to be administered by (fortnightly) intramuscular injection. +Option C: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms. +Option D: Enalaprilat is given by intravenous injection, usually as the dihydrate. +" D +134780 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +Option B: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option C: It is an immunomodulatory and antineoplastic agent used in the therapy of multiple myeloma. +Option D: It is an immunomodulatory and antineoplastic agent. +" C +12699 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C(=O)N)N=O +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. +Option B: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option C: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +Option D: It causes dermatitis upon acute exposure in humans. +" D +5966 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option B: It is an indirect-acting parasympathomimetic agent used to treat glaucoma. +Option C: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +Option D: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. +" B +5284632 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC[N+]2(C1)[C@@H]3CC[C@H]2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. +Option B: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +Option C: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option D: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. +" A +4771 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(CC1=CC=CC=C1)N +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an angiotensin II receptor blocker used to treat hypertension and reduce cardiovascular mortality after myocardial infarction. +Option B: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. +Option C: It is an angiotensin II receptor blocker used in the therapy of hypertension and diabetic nephropathy. +Option D: It is a sympathomimetic amine and anorectic agent used for the short-term therapy of obesity. +" D +11715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)CBr +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. +Option B: It is an anthelmintic agent used commonly for roundworm (pinworm and hookworm) infections, trichinosis, capillariasis, and toxocariasis, and other parasitic worm infections. +Option C: It is a non-steroidal agent efficacious in improving disease severity, reducing the risk of infection, and reducing the signs and symptoms in patients 2 years old and older. +Option D: It is/was considered to be a rapid-acting casualty-producing agent capable of causing casualties within minutes of dissemination as a chemical warfare or riot control agent. +" D +4205 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4 +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option B: It is a tetracyclic piperazino-azepine antidepressant agent initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. +Option C: It is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. +Option D: It is an antithrombotic and platelet-reducing agent used to treat the thrombocythemia associated with myeloproliferative diseases. +" B +443879 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C=C1)O)[C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2 +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option B: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. +Option C: It is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. +Option D: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +" D +24393 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [O-]S(=O)(=O)[O-].[Fe+2] +Question about this molecule: Which kind of agent is this molecule? +Option A: It causes dermatitis upon acute exposure in humans. +Option B: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option C: It is a synthetic agent used in the treatment of iron deficiency. +Option D: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +" C +444031 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(C[C@@H]1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5 +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome. +Option B: It is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome. +Option C: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. +Option D: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +" A +2724385 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)O +Question about this molecule: Which kind of agent is this molecule? +Option A: It is a selective relaxant binding agent. +Option B: It is one of the oldest cardiovascular medications used today. +Option C: It is an agent thought to have disinfectant properties and used as an expectorant. +Option D: It causes dermatitis upon acute exposure in humans. +" B +7029 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C(C)C(=O)C1=CC=CC=C1 +Question about this molecule: Which kind of agent is this molecule? +Option A: It is a sympathomimetic amine and anorectic agent used for the short-term therapy of obesity. +Option B: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome. +Option C: It is an angiotensin II receptor blocker used in the therapy of hypertension and diabetic nephropathy. +Option D: It is an angiotensin II receptor blocker used to treat hypertension and reduce cardiovascular mortality after myocardial infarction. +" A +460 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC=CC=C1O +Question about this molecule: Which kind of agent is this molecule? +Option A: It is an agent thought to have disinfectant properties and used as an expectorant. +Option B: It is an anticholinergic agent used to treat urinary incontinence and hyperactive bladder syndrome. +Option C: It is an immunomodulatory and antineoplastic agent. +Option D: It is an immunomodulatory and antineoplastic agent used in the therapy of multiple myeloma. +" A +6918585 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CSC[C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]8[C@H](O[C@@H]([C@@H]([C@H]8O)O)O[C@@H]9[C@H](O[C@H](O2)[C@@H]([C@H]9O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)O)O)C(=O)O +Question about this molecule: Which kind of agent is this molecule? +Option A: It causes dermatitis upon acute exposure in humans. +Option B: It is one of the oldest cardiovascular medications used today. +Option C: It is a selective relaxant binding agent. +Option D: It is an agent thought to have disinfectant properties and used as an expectorant. +" C +3345 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=CC=C3 +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is an Opioid Agonist. +Option B: It is a GABA receptor agonist. +Option C: It is a gonadotropin releasing hormone (GnRH) agonist. +Option D: It is a selective alpha-adrenergic receptor agonist. +" A +4095 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2 +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a gonadotropin releasing hormone (GnRH) agonist. +Option B: It is a GABA receptor agonist. +Option C: It is an Opioid Agonist. +Option D: It is a selective alpha-adrenergic receptor agonist. +" C +5358 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is an Opioid Agonist. +Option B: It is a selective alpha-adrenergic receptor agonist. +Option C: It is a gonadotropin releasing hormone (GnRH) agonist. +Option D: It is a Serotonin-1b and Serotonin-1d Receptor Agonist. +" D +5284603 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a GABA receptor agonist. +Option B: It is a selective alpha-adrenergic receptor agonist. +Option C: It is a gonadotropin releasing hormone (GnRH) agonist. +Option D: It is an Opioid Agonist. +" D +5284371 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](C=C4)O +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a gonadotropin releasing hormone (GnRH) agonist. +Option B: It is a selective alpha-adrenergic receptor agonist. +Option C: It is an Opioid Agonist. +Option D: It is a GABA receptor agonist. +" C +5288826 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a selective alpha-adrenergic receptor agonist. +Option B: It is a GABA receptor agonist. +Option C: It is a gonadotropin releasing hormone (GnRH) agonist. +Option D: It is an Opioid Agonist. +" D +5284569 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4 +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a gonadotropin releasing hormone (GnRH) agonist. +Option B: It is an Opioid Agonist. +Option C: It is a GABA receptor agonist. +Option D: It is a selective alpha-adrenergic receptor agonist. +" B +41693 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CS3)COC +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a selective alpha-adrenergic receptor agonist. +Option B: It is a gonadotropin releasing hormone (GnRH) agonist. +Option C: It is a GABA receptor agonist. +Option D: It is an Opioid Agonist. +" D +33741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)OC)O +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is an Opioid Agonist. +Option B: It is a GABA receptor agonist. +Option C: It is a gonadotropin releasing hormone (GnRH) agonist. +Option D: It is a selective alpha-adrenergic receptor agonist. +" A +3955 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C(=O)C(CCN1CCC(CC1)(C2=CC=C(C=C2)Cl)O)(C3=CC=CC=C3)C4=CC=CC=C4 +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a selective alpha-adrenergic receptor agonist. +Option B: It is a GABA receptor agonist. +Option C: It is a gonadotropin releasing hormone (GnRH) agonist. +Option D: It is an Opioid Agonist. +" D +60815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a selective alpha-adrenergic receptor agonist. +Option B: It is a GABA receptor agonist. +Option C: It is a gonadotropin releasing hormone (GnRH) agonist. +Option D: It is an Opioid Agonist. +" D +119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)CN +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a cannabinoid receptor agonist. +Option B: It is a beta-3 adrenergic agonist. +Option C: It is a selective alpha-adrenergic receptor agonist. +Option D: It is a GABA receptor agonist. +" D +5284570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3C(=O)CC4 +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is a GABA receptor agonist. +Option B: It is a gonadotropin releasing hormone (GnRH) agonist. +Option C: It is an Opioid Agonist. +Option D: It is a selective alpha-adrenergic receptor agonist. +" C +10100 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)O[C@](CC1=CC=CC=C1)(C2=CC=CC=C2)[C@H](C)CN(C)C +Question about this molecule: Which kind of agonist is this molecule? +Option A: It is an Opioid Agonist. +Option B: It is a GABA receptor agonist. +Option C: It is a selective alpha-adrenergic receptor agonist. +Option D: It is a gonadotropin releasing hormone (GnRH) agonist. +" A +3035 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(=C(Cl)Cl)C2=CC=C(C=C2)Cl)Cl +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used mainly in agriculture to protect field and vegetable crops. +Option B: It is widely used in farming, particularly in wheat farming. +Option C: It is widely used in agriculture. +Option D: It was once a widely used pesticide. +" D +4004 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used mainly in agriculture to protect field and vegetable crops. +Option B: It is used to kill insects on farm crops and in gardens. +Option C: It is widely used in farming, particularly in wheat farming. +Option D: It is used on corn crops, including popcorn. +" B +2566 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(CC2=C(O1)C(=CC=C2)OC(=O)NC)C +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used as an agricultural insecticide, acaricide, bactericide, and fungicide. +Option B: It is mainly used in agriculture as insecticides, herbicides, and fungicides. +Option C: It is used as an agricultural insecticide and nematocide. +Option D: It is used as a systemic agricultural insecticide, acaricide, and nematocide. +" D +1982 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NP(=O)(OC)SC +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It controls leaf miners, caterpillars, sawflies, and thrips in crops, turf, and forestry. +Option B: It is sold for use on grapes, potatoes, tomatoes, hops, sugarbeets, and other vegetable crops. +Option C: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics. +Option D: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +" A +13754 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(OCC)OC1=NC(=NC(=C1)C)C(C)C +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is approved for agricultural uses. +Option B: It is a systemic agricultural fungicide. +Option C: It is an agricultural herbicide. +Option D: It is a systemic agricultural insecticide. +" A +24726 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(/C=C/Cl)Cl +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is effective against broadleaf weeds and grasses and is used agriculturally on fields growing soybeans, peanuts, peas, and rice. +Option B: It is widely used as a preplanting soil fumigant for the control of nematodes in agriculture. +Option C: It is used as a preplanting soil fumigant for the control of nematodes. +Option D: It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry. +" C +5364079 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC(=O)NC(=O)/C(=N/OC)/C#N +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option B: It is sold for use on grapes, potatoes, tomatoes, hops, sugarbeets, and other vegetable crops. +Option C: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +Option D: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics. +" B +34766 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCSCC1=CC=CC=C1OC(=O)NC +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is a nonsystemic foliar agricultural fungicide, especially for potatoes. +Option B: It is a systemic agricultural fungicide. +Option C: It is a systemic agricultural insecticide. +Option D: It is an agricultural herbicide. +" C +42586 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is an agricultural herbicide. +Option B: It is a nonsystemic foliar agricultural fungicide, especially for potatoes. +Option C: It is a systemic agricultural insecticide. +Option D: It is a systemic agricultural fungicide. +" D +2730 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)OC1=NC(=C(C=C1Cl)Cl)Cl +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used to control ticks on cattle and as a spray to control crop pests. +Option B: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option C: It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry. +Option D: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +" A +91731 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is a nonsystemic foliar agricultural fungicide, especially for potatoes. +Option B: It is a broad-spectrum fungicide used in agriculture. +Option C: It is a systemic agricultural fungicide. +Option D: It is a systemic agricultural insecticide. +" B +5388936 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3CCC(=O)C[C@H]3C(=O)N[C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry. +Option B: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option C: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics. +Option D: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +" A +104926 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C(C1C(=O)OC(C#N)C2=CC(=C(C=C2)F)OC3=CC=CC=C3)C=C(Cl)Cl)C +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used to control insects in some stored agricultural products and to sterilize medical equipment and supplies. +Option B: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +Option C: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option D: Its primary agricultural uses have been for control of chewing and sucking insects on various crops. +" D +3118 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)SCCSCC +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used mainly in agriculture to protect field and vegetable crops. +Option B: It is widely used in farming, particularly in wheat farming. +Option C: It is used to kill insects on farm crops and in gardens. +Option D: It is used on corn crops, including popcorn. +" A +6354 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CO1 +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +Option B: It is used to control insects in some stored agricultural products and to sterilize medical equipment and supplies. +Option C: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option D: Its primary agricultural uses have been for control of chewing and sucking insects on various crops. +" B +93516 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OC1=CN=C(N=C1)C(C)(C)C)OC(C)C +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is widely used in farming, particularly in wheat farming. +Option B: It is used to kill insects on farm crops and in gardens. +Option C: It is used on corn crops, including popcorn. +Option D: It is used mainly in agriculture to protect field and vegetable crops. +" C +23978 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Cu] +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option B: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics. +Option C: It is sold for use on grapes, potatoes, tomatoes, hops, sugarbeets, and other vegetable crops. +Option D: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +" B +15531 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C=C(C(=C1Br)O)Br)C#N +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is sold for use on grapes, potatoes, tomatoes, hops, sugarbeets, and other vegetable crops. +Option B: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +Option C: It is effective against broadleaf weeds and grasses and is used agriculturally on fields growing soybeans, peanuts, peas, and rice. +Option D: It is effective in the control of weeds in cereal, corn, sorghum, onions, flax, mint, turf, and on non-cropland. +" D +24462 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [O-]S(=O)(=O)[O-].[Cu+2] +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used primarily for agricultural purposes, as a pesticide, germicide, feed additive, and soil additive. +Option B: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics. +Option C: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option D: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +" A +44073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1C(F)(F)F)Cl)OC2=CC(=C(C=C2)[N+](=O)[O-])C(=O)O +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is effective against broadleaf weeds and grasses and is used agriculturally on fields growing soybeans, peanuts, peas, and rice. +Option B: It is sold for use on grapes, potatoes, tomatoes, hops, sugarbeets, and other vegetable crops. +Option C: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +Option D: It is effective in the control of weeds in cereal, corn, sorghum, onions, flax, mint, turf, and on non-cropland. +" A +8370 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)Cl +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used as an agricultural insecticide, acaricide, bactericide, and fungicide. +Option B: It is used as a systemic agricultural insecticide, acaricide, and nematocide. +Option C: It is used as an agricultural insecticide and nematocide. +Option D: It is an agricultural fungicide, belonging to the family of Chlorobenzenes. +" D +3286 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)SCSP(=S)(OCC)OCC +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +Option B: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics. +Option C: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables. +Option D: It is sold for use on grapes, potatoes, tomatoes, hops, sugarbeets, and other vegetable crops. +" C +43234 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)Cl)Cl +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics. +Option B: It is effective in the control of weeds in cereal, corn, sorghum, onions, flax, mint, turf, and on non-cropland. +Option C: It is used agriculturally on turfgrasses, mushrooms, corn, wild rice, peanuts, almonds, sorghum, oats, pecans, apricots, peaches, nectarines, plums, and prunes. +Option D: It is effective against broadleaf weeds and grasses and is used agriculturally on fields growing soybeans, peanuts, peas, and rice. +" C +5280970 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(/C=C\\Cl)Cl +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is effective against broadleaf weeds and grasses and is used agriculturally on fields growing soybeans, peanuts, peas, and rice. +Option B: It is used as a preplanting soil fumigant for the control of nematodes. +Option C: It is widely used as a preplanting soil fumigant for the control of nematodes in agriculture. +Option D: It is used to treat infections with gram-positive organisms and as a growth promoter in cattle, swine, and poultry. +" C +4420 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(OC)OC(C(Cl)(Cl)Br)Br +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used as an agricultural insecticide, acaricide, bactericide, and fungicide. +Option B: It is used as a systemic agricultural insecticide, acaricide, and nematocide. +Option C: It is used as an agricultural insecticide and nematocide. +Option D: It is mainly used in agriculture as insecticides, herbicides, and fungicides. +" A +5353758 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=N\\OC(=O)NC)/SC +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used as an agricultural insecticide and nematocide. +Option B: It is used as an agricultural insecticide, acaricide, bactericide, and fungicide. +Option C: It is used as a systemic agricultural insecticide, acaricide, and nematocide. +Option D: It is mainly used in agriculture as insecticides, herbicides, and fungicides. +" A +6294 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is used to control insects in some stored agricultural products and to sterilize medical equipment and supplies. +Option B: Its agricultural use has been banned worldwide due to its toxicity and tendency to bioaccumulate. +Option C: Its primary agricultural uses have been for control of chewing and sucking insects on various crops. +Option D: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport. +" B +16653 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCSC(=O)N1CCCCCC1 +Question about this molecule: How can the molecule be used as a/an agricultural chemical +Option A: It is mainly used in agriculture as insecticides, herbicides, and fungicides. +Option B: It is used as an agricultural insecticide and nematocide. +Option C: It is used as a systemic agricultural insecticide, acaricide, and nematocide. +Option D: It is used as an agricultural insecticide, acaricide, bactericide, and fungicide. +" A +4095 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2 +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. +Option B: It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. +Option C: It is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. +Option D: The analgesic properties of Tramadol can be attributed to norepinephrine and serotonin reuptake blockade in the CNS, which inhibits pain transmission in the spinal cord. +" C +5284603 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. +Option B: It is a semisynthetic derivative of codeine that acts as a narcotic analgesic more potent and addicting than codeine. +Option C: It is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. +Option D: It is a sublingually and transdermally available, semisynthetic opioid analgesic, which is used as an analgesic and for management of opioid dependence. +" B +8361 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)OC(=O)C2=CC=CC=C2O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). +Option B: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +Option C: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +Option D: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +" B +1548943 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. +Option B: The analgesic properties of Tramadol can be attributed to norepinephrine and serotonin reuptake blockade in the CNS, which inhibits pain transmission in the spinal cord. +Option C: It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. +Option D: It is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. +" A +3059 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1C2=C(C=C(C=C2)F)F)C(=O)O)O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It possesses anti-inflammatory, analgesic and antipyretic activity. +Option B: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option C: It has analgesic and anti-inflammatory properties. +Option D: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +" A +6880 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)C(=O)OCCO)O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +Option B: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option C: It is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). +Option D: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +" D +5288826 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +Option B: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option C: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +Option D: It is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). +" B +3000715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(C)C1(C(=O)NC(=S)NC1=O)CC +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option B: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +Option C: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +Option D: It does not produce any excitation but has poor analgesic and muscle relaxant properties. +" D +5284569 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4 +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +Option B: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +Option C: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option D: It is a narcotic analgesic related to codeine, but more potent and more addicting by weight. +" D +33741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)OC)O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. +Option B: The analgesic properties of Tramadol can be attributed to norepinephrine and serotonin reuptake blockade in the CNS, which inhibits pain transmission in the spinal cord. +Option C: It is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. +Option D: It is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. +" B +338 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)C(=O)O)O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: Its salts, the salicylates, are used as analgesics. +Option B: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +Option C: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option D: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +" A +6009 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N(N1C)C2=CC=CC=C2)N(C)C +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. +Option B: It is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties that carries a risk of agranulocytosis. +Option C: The analgesic properties of Tramadol can be attributed to norepinephrine and serotonin reuptake blockade in the CNS, which inhibits pain transmission in the spinal cord. +Option D: It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. +" B +1983 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NC1=CC=C(C=C1)O +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option B: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +Option C: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain. +Option D: It is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). +" D +5284570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3C(=O)CC4 +Question about this molecule: Which kind of analgesic is this molecule? +Option A: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. +Option B: It is a sublingually and transdermally available, semisynthetic opioid analgesic, which is used as an analgesic and for management of opioid dependence. +Option C: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate. +Option D: It is an opioid analgesic derived from morphine and used mainly as an analgesic. +" D +124034 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=C(C=C3)O)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an endothelin receptor antagonist. +Option B: It is an orexin receptor antagonist. +Option C: It is an adenosine A1 receptor antagonist. +Option D: It is an aryl hydrocarbon receptor antagonist. +" C +2905 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(=O)C(C1=CC=CC=C1)C2(CCCC2)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a GABA antagonist and a serotonergic antagonist. +Option C: It is a muscarinic antagonist. +Option D: It is a muscarinic antagonist and a histamine antagonist. +" C +4748 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a dopamine antagonist. +Option B: It is a histamine antagonist. +Option C: It is a dopaminergic antagonist. +Option D: It is a dopamine receptor D2 antagonist. +" C +4744 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=CC=CC=C42 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a dopamine receptor D2 antagonist. +Option B: It is a dopamine antagonist. +Option C: It is a histamine antagonist. +Option D: It is a dopaminergic antagonist. +" D +11588811 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCC1=CC(=CC=C1)NC(=O)[C@@H](COP(=O)(O)O)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor. +Option B: It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. +Option C: It is a potent antagonist for both S1P1 and S1P3 receptors. +Option D: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +" C +9576916 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)C[C@@H]1C[C@H](NC1=O)COC2=CC=C(C=C2)C3=CC=C(C=C3)/C(=N/C(=O)OC)/N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +Option B: It is a platelet glycoprotein-IIb/IIIa receptor antagonist. +Option C: It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor. +Option D: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +" B +27400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonergic antagonist. +Option B: It is a serotonin antagonist. +Option C: It is a serotonin and tryptamine antagonist. +Option D: It is a serotonin receptor agonist. +" A +45485025 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1[C@@H]2[C@H](C3=C(O2)C=CC(=C3)/C=C/C(=O)NCCCCN=C(N)N)C(=O)NCCCCN=C(N)N)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an alpha-adrenergic antagonist. +Option B: It is a selective alpha-1a adrenergic antagonist. +Option C: It is a beta-adrenergic antagonist. +Option D: It is an adrenergic antagonist. +" D +1548953 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCOC1=CC=C(C=C1)/C(=C(\\C2=CC=CC=C2)/Cl)/C3=CC=CC=C3 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an aryl hydrocarbon receptor antagonist. +Option B: It is an orexin receptor antagonist. +Option C: It is an estrogen antagonist. +Option D: It is an estrogen receptor antagonist. +" C +104741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an estrogen receptor antagonist. +Option B: It is an estrogen antagonist. +Option C: It is an orexin receptor antagonist. +Option D: It is an aryl hydrocarbon receptor antagonist. +" A +39468 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NC[C@@H](COC1=CC=CC2=C1CCCC2=O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a beta-adrenergic antagonist. +Option B: It is an alpha-adrenergic antagonist. +Option C: It is a selective alpha-1a adrenergic antagonist. +Option D: It is an adrenergic antagonist. +" A +20055509 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4.O.O.O.Br +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist. +Option B: It is a GABA antagonist and a serotonergic antagonist. +Option C: It is a muscarinic antagonist and a histamine antagonist. +Option D: It is a H1-receptor antagonist and a muscarinic antagonist. +" A +474303 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=CC2=C(C=C1)C(=CN2)C3=C(C(=O)C(=C(C3=O)O)C4=CNC5=CC=CC=C54)O)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an endothelin receptor antagonist. +Option B: It is an epidermal growth factor receptor antagonist. +Option C: It is an angiotensin II receptor antagonist. +Option D: It is an angiotensin receptor antagonist. +" B +129211 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=CC=CC=C1OCCN[C@H](C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an alpha-adrenergic antagonist. +Option B: It is an alpha1 adrenoceptor antagonist. +Option C: It is a selective alpha-1a adrenergic antagonist. +Option D: It is an adrenergic antagonist. +" B +33624 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a beta-adrenergic antagonist. +Option B: It is an adrenergic antagonist. +Option C: It is an alpha-adrenergic antagonist. +Option D: It is a selective alpha-1a adrenergic antagonist. +" A +1884 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C=C1Cl)NC(=CC2=O)C(=O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a metabotropic glutamate receptor antagonist. +Option B: It is an NMDA glutamate receptor antagonist. +Option C: It is a glutamate receptor antagonist. +Option D: It is a NMDA receptor antagonist. +" B +60547 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CC2=C1NC3=C2C=C(C=C3)F)CCCC4=CN=CC=C4 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a dopamine receptor D2 antagonist. +Option B: It is a dopaminergic antagonist. +Option C: It is a histamine antagonist. +Option D: It is a dopamine antagonist. +" A +474302 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=CC2=C(C=C1)NC=C2C3=C(C(=O)C(=C(C3=O)O)C4=CNC5=CC=CC=C54)O)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an endothelin receptor antagonist. +Option B: It is an angiotensin II receptor antagonist. +Option C: It is an angiotensin receptor antagonist. +Option D: It is an epidermal growth factor receptor antagonist. +" D +6603108 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4.Br +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a GABA antagonist and a serotonergic antagonist. +Option B: It is a H1-receptor antagonist and a muscarinic antagonist. +Option C: It is a muscarinic antagonist and a histamine antagonist. +Option D: It is a muscarinic antagonist. +" D +135564864 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NN(C(=O)N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +Option B: It is a Substance P/Neurokinin-1 Receptor Antagonist. +Option C: It is a substance P/neurokinin 1 (NK1) receptor antagonist. +Option D: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +" C +135564864 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NN(C(=O)N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a neurokinin-1 receptor antagonist. +Option B: It is a vasopressin receptor antagonist. +Option C: It is a mu-opioid receptor antagonist. +Option D: It is a melanin-concentrating hormone receptor antagonist. +" A +4705 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an endothelin receptor antagonist. +Option B: It is an angiotensin II receptor antagonist. +Option C: It is an angiotensin receptor antagonist. +Option D: It is an epidermal growth factor receptor antagonist. +" D +168993 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonin receptor agonist. +Option B: It is a serotonin antagonist. +Option C: It is a serotonin and tryptamine antagonist. +Option D: It is a serotonergic antagonist. +" B +5464092 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O.Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a metabotropic glutamate receptor antagonist. +Option B: It is an NMDA glutamate receptor antagonist. +Option C: It is a mu-opioid receptor antagonist. +Option D: It is a glutamate receptor antagonist. +" C +6890 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC1=CNC2=CC=CC=C21 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonin receptor agonist. +Option B: It is a serotonin antagonist. +Option C: It is a serotonin and tryptamine antagonist. +Option D: It is a serotonergic antagonist. +" D +11957576 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C2=CC=CC=C2N(C1=O)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F)C.Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +Option B: It is an H1 receptor agonist and partial H3 receptor antagonist used for the treatment of obese individuals and for other weight management indications. +Option C: It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. +Option D: It is a potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor. +" D +2444 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=C(C=C2)Br +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist. +Option B: It is a glutamate receptor antagonist. +Option C: It is a beta-1 adrenoceptor antagonist. +Option D: It is an alpha1 adrenoceptor antagonist. +" A +444030 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(C[C@@H]1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5.Br +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option B: It is a competitive, reversible antagonist of muscarinic receptors. +Option C: It is a selective antagonist for the M3 muscarinic acetylcholine receptor. +Option D: It is an agonist at nicotinic cholinergic receptors. +" C +6834 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCC(C1=CC=C(C=C1)Br)C2=CC=CC=N2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist. +Option B: It is an alpha1 adrenoceptor antagonist. +Option C: It is a glutamate receptor antagonist. +Option D: It is a beta-1 adrenoceptor antagonist. +" A +4830 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCN(CC1)C2(CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)C(=O)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonergic antagonist and a dopaminergic antagonist. +Option B: It is a muscarinic antagonist and a histamine antagonist. +Option C: It is a serotonergic antagonist. +Option D: It is a GABA antagonist and a serotonergic antagonist. +" A +442292 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=C)[C@@H]1[C@@H]2[C@@H]3[C@@]4([C@]([C@H]1C(=O)O2)(C[C@@H]5[C@]4(O5)C(=O)O3)O)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonergic antagonist. +Option B: It is a GABA antagonist and a serotonergic antagonist. +Option C: It is a serotonergic antagonist and a dopaminergic antagonist. +Option D: It is a muscarinic antagonist and a histamine antagonist. +" B +101597 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O.Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a GABA antagonist and a serotonergic antagonist. +Option B: It is a muscarinic antagonist and a histamine antagonist. +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a muscarinic antagonist. +" D +5282409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=C\\C(=O)O)\\C(=O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +Option B: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +" C +4282258 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C2=CC=CC=C2N(C1=O)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonin antagonist. +Option B: It is a serotonergic antagonist. +Option C: It is a serotonin receptor agonist. +Option D: It is a serotonin and tryptamine antagonist. +" B +162321 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@]1(CCC=C[C@@H]1NC)C2=CC=CC=C2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an NMDA glutamate receptor antagonist. +Option B: It is a NMDA receptor antagonist. +Option C: It is a metabotropic glutamate receptor antagonist. +Option D: It is a glutamate receptor antagonist. +" B +216322 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC2=C(N1)CCN(C3=CC=CC=C32)C(=O)C4=CC=C(C=C4)NC(=O)C5=CC=CC=C5C6=CC=CC=C6.Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a glutamate receptor antagonist. +Option B: It is a vasopressin receptor antagonist. +Option C: It is a mu-opioid receptor antagonist. +Option D: It is a melanin-concentrating hormone receptor antagonist. +" B +122824 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C(C)CN1C2=CC=CC=C2SC3=CC=CC=C31.Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a muscarinic antagonist. +Option C: It is a muscarinic antagonist and a histamine antagonist. +Option D: It is a GABA antagonist and a serotonergic antagonist. +" B +181458 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC12CC3CC(C1)(CC(C3)(C2)N)C.Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a glutamate receptor antagonist. +Option B: It is a metabotropic glutamate receptor antagonist. +Option C: It is a NMDA receptor antagonist. +Option D: It is an NMDA glutamate receptor antagonist. +" C +3100 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a beta-1 adrenoceptor antagonist. +Option B: It is a H1-receptor antagonist. +Option C: It is a glutamate receptor antagonist. +Option D: It is an alpha1 adrenoceptor antagonist. +" B +657308 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[N+]1([C@@H]2CC[C@H]1CC(C2)OC(=O)C(CO)C3=CC=CC=C3)C.[Br-] +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist. +Option B: It is a GABA antagonist and a serotonergic antagonist. +Option C: It is a muscarinic antagonist and a histamine antagonist. +Option D: It is a H1-receptor antagonist and a muscarinic antagonist. +" A +60854 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a second-generation histamine H1 antagonist. +Option B: It is a histamine antagonist. +Option C: It is a H1 histamine receptor antagonist. +Option D: It is a histamine H1 antagonist. +" B +16960 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC[C@@H](C1=CC=C(C=C1)Br)C2=CC=CC=N2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a glutamate receptor antagonist. +Option B: It is an alpha1 adrenoceptor antagonist. +Option C: It is a beta-1 adrenoceptor antagonist. +Option D: It is a H1-receptor antagonist. +" D +2564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a beta-1 adrenoceptor antagonist. +Option B: It is an alpha1 adrenoceptor antagonist. +Option C: It is a H1-receptor antagonist. +Option D: It is a glutamate receptor antagonist. +" C +11519070 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[N+]2(CCC1(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)CCOCC5=CC=CC=C5 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a muscarinic antagonist. +Option C: It is a muscarinic antagonist and a histamine antagonist. +Option D: It is a GABA antagonist and a serotonergic antagonist. +" B +656593 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC1=CC=C(C=C1)C[N+]2([C@@H]3CC[C@H]2CC(C3)OC(=O)[C@H](CO)C4=CC=CC=C4)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist. +Option B: It is a GABA antagonist and a serotonergic antagonist. +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a muscarinic antagonist and a histamine antagonist. +" A +446355 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@](C1=CC=C(C=C1)C(=O)O)(C(=O)O)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a glutamate receptor antagonist. +Option B: It is a metabotropic glutamate receptor antagonist. +Option C: It is a NMDA receptor antagonist. +Option D: It is an NMDA glutamate receptor antagonist. +" B +11519069 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[N+]2(CCC1(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)CCOCC5=CC=CC=C5.[Br-] +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a GABA antagonist and a serotonergic antagonist. +Option B: It is a muscarinic antagonist. +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a muscarinic antagonist and a histamine antagonist. +" B +15736 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[NH+](C)CCOC(C1=CC=CC=C1)C2=CC=C(C=C2)Br.[Cl-] +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a second-generation histamine H1 antagonist. +Option B: It is a histamine antagonist. +Option C: It is a histamine H1 antagonist. +Option D: It is a H1 histamine receptor antagonist. +" B +3869 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an adrenergic antagonist. +Option B: It is an alpha-adrenergic antagonist. +Option C: It is a beta-adrenergic antagonist. +Option D: It is a selective alpha-1a adrenergic antagonist. +" B +656603 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[N+]1([C@@H]2CC[C@H]1CC(C2)OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)CCF +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a muscarinic antagonist and a histamine antagonist. +Option C: It is a GABA antagonist and a serotonergic antagonist. +Option D: It is a muscarinic antagonist. +" D +4926 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a dopamine antagonist. +Option B: It is a histamine antagonist. +Option C: It is a dopaminergic antagonist. +Option D: It is a dopamine receptor D2 antagonist. +" C +21453 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)CC2=CN=C(N=C2N)N)OC +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist and a histamine antagonist. +Option B: It is a H1-receptor antagonist and a muscarinic antagonist. +Option C: It is a muscarinic antagonist. +Option D: It is a folic acid antagonist. +" D +444031 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(C[C@@H]1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a muscarinic antagonist. +Option C: It is a GABA antagonist and a serotonergic antagonist. +Option D: It is a muscarinic antagonist and a histamine antagonist. +" B +10467350 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN2C(CN1)C3=CC=CC=C3CC4=C2N=CC=C4 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a beta-1 adrenoceptor antagonist. +Option B: It is a glutamate receptor antagonist. +Option C: It is an alpha1 adrenoceptor antagonist. +Option D: It is a H1-receptor antagonist. +" D +5284632 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC[N+]2(C1)[C@@H]3CC[C@H]2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist and a histamine antagonist. +Option B: It is a muscarinic antagonist. +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a GABA antagonist and a serotonergic antagonist. +" B +160883 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist and a histamine antagonist. +Option B: It is a muscarinic antagonist. +Option C: It is a GABA antagonist and a serotonergic antagonist. +Option D: It is a H1-receptor antagonist and a muscarinic antagonist. +" B +2911 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a muscarinic antagonist. +Option C: It is a GABA antagonist and a serotonergic antagonist. +Option D: It is a muscarinic antagonist and a histamine antagonist. +" B +4634 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist. +Option B: It is a GABA antagonist and a serotonergic antagonist. +Option C: It is a muscarinic antagonist and a histamine antagonist. +Option D: It is a H1-receptor antagonist and a muscarinic antagonist. +" A +4601 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a NMDA receptor antagonist. +Option B: It is a metabotropic glutamate receptor antagonist. +Option C: It is a glutamate receptor antagonist. +Option D: It is an NMDA glutamate receptor antagonist. +" A +135413536 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=C(C=C4)F +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +Option B: It is a Substance P/Neurokinin-1 Receptor Antagonist. +Option C: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +Option D: It is a substance P/neurokinin 1 (NK1) receptor antagonist. +" A +161174 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1)Cl)N)C2=CNC=C2Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an estrogen receptor antagonist. +Option B: It is an androgen antagonist. +Option C: It is an aryl hydrocarbon receptor antagonist. +Option D: It is an estrogen antagonist. +" B +83823 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option C: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +Option D: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +" B +49852363 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCC[NH+](C)C.[Cl-] +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1-receptor antagonist and a muscarinic antagonist. +Option B: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +Option C: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +Option D: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +" D +119570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN[C@H]1CCC2=C(C1)SC(=N2)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a dopamine antagonist. +Option B: It is a dopaminergic antagonist. +Option C: It is a dopamine receptor D2 antagonist. +Option D: It is a selective dopamine receptor agonist. +" D +135410875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonergic antagonist and a dopaminergic antagonist. +Option B: It is a parenterally administered folate antagonist and antineoplastic agent. +Option C: It is a GABA antagonist and a serotonergic antagonist. +Option D: It is a folate antagonist and antineoplastic agent. +" B +54766 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)OC(=O)N(C)C)OC(=O)N(C)C)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective α1-receptor agonist. +Option B: It is a long acting beta-adrenoceptor agonist. +Option C: It is a selective beta-2 adrenergic agonist. +Option D: It is a selective β3 adrenoceptor agonist. +" B +10311306 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC[C@]2(CC[C@]3(CCC(=O)N3)CN2)C4=CC=CC=C4 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a substance P/neurokinin 1 (NK1) receptor antagonist. +Option B: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +Option C: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +Option D: It is a Substance P/Neurokinin-1 Receptor Antagonist. +" D +5910 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H]1[C@H](COC1=O)CC2=CN=CN2C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist. +Option B: It is a muscarinic agonist. +Option C: It is a long-acting muscarinic antagonist (LAMA). +Option D: It is a slowly hydrolyzed muscarinic agonist. +" D +135403648 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a folic acid antagonist. +Option B: It is used to counteract the toxic effects of folic acid antagonists. +Option C: It is a muscarinic antagonist and a histamine antagonist. +Option D: It is a muscarinic antagonist. +" B +5358 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective serotonin agonist. +Option B: It is a serotonin antagonist. +Option C: It is a serotonin and tryptamine antagonist. +Option D: It is a serotonin receptor agonist. +" D +3325 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(N=C(S1)N=C(N)N)CSCCC(=NS(=O)(=O)N)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a histamine H1 antagonist. +Option B: It is a H1 histamine receptor antagonist. +Option C: It is a histamine type 2 receptor antagonist (H2 blocker). +Option D: It is a second-generation histamine H1 antagonist. +" C +5732 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a benzodiazepine receptor agonist and hypnotic used as a sleeping pill. +Option B: It is a Benzodiazepine Antagonist. +Option C: It is a benzodiazepine receptor agonist. +Option D: It is a benzodiazepine receptor agonist used for the treatment of insomnia. +" D +2083 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an alpha-1 selective adrenergic agonist commonly used in the treatment of migraine disorders. +Option B: It is a nicotinic antagonist used as a ganglionic blocking agent in hypertension. +Option C: It is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. +Option D: It is a nonselective alpha-1 adrenergic antagonist used in the therapy of benign prostatic hypertrophy. +" C +2366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC1=CC=CC=N1 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an H1 receptor agonist and partial H3 receptor antagonist used for the treatment of obese individuals and for other weight management indications. +Option B: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option C: It is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. +Option D: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +" A +4054 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC12CC3CC(C1)(CC(C3)(C2)N)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia. +Option B: It is an oral N-methyl-D-aspartate glutamate receptor antagonist used in the therapy of Alzheimer disease and dementia. +Option C: It is an H1 receptor agonist and partial H3 receptor antagonist used for the treatment of obese individuals and for other weight management indications. +Option D: It is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. +" B +2725 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. +Option B: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option C: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +Option D: It is a histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. +" D +2756 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(N=CN1)CSCCNC(=NC)NC#N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a beta-1 adrenoceptor antagonist. +Option B: It is a Leukotriene Receptor Antagonist. +Option C: It is a protease-activated receptor-1 antagonist. +Option D: It is a Histamine-2 Receptor Antagonist. +" D +5284596 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an alpha-adrenergic antagonist. +Option B: It is an orally available cannabinoid agonist. +Option C: It is an Opioid Antagonist. +Option D: It is an adrenergic antagonist. +" C +8223 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1(C(=O)N2[C@H](C(=O)N3CCC[C@H]3[C@@]2(O1)O)CC4=CC=CC=C4)NC(=O)[C@H]5CN([C@@H]6CC7=CNC8=CC=CC(=C78)C6=C5)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. +Option B: It is a nonselective alpha-1 adrenergic antagonist used in the therapy of benign prostatic hypertrophy. +Option C: It is an alpha-1 selective adrenergic agonist commonly used in the treatment of migraine disorders. +Option D: It is a nicotinic antagonist used as a ganglionic blocking agent in hypertension. +" C +3343 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CC1=CC=C(C=C1)O)NCC(C2=CC(=CC(=C2)O)O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an adrenergic beta-2 agonist used as a bronchodilator and tocolytic. +Option B: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option C: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +Option D: It is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia. +" A +6337614 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@@H]4CN5CCC4CC5 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an antagonist of 5-HT3 receptors. +Option B: It is a glutamate receptor antagonist. +Option C: It is a 5-HT2 antagonist. +Option D: It is a 5-HT3 and 5-HT4 receptors antagonist. +" A +55245 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +Option B: It is a H1-receptor antagonist and a muscarinic antagonist. +Option C: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option D: It is a glucocorticoid receptor antagonist. +" D +4601 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist and a histamine antagonist. +Option B: It is a GABA antagonist and a serotonergic antagonist. +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a muscarinic antagonist. +" D +5095 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective dopamine receptor agonist. +Option B: It is a dopamine receptor D2 antagonist. +Option C: It is a dopaminergic antagonist. +Option D: It is a dopamine antagonist. +" A +2444 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=C(C=C2)Br +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +Option B: It antagonizes the effects of histamine on HA-receptors. +Option C: It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. +Option D: It is a potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor. +" B +444 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an adrenergic antagonist. +Option B: It is an alpha-adrenergic antagonist. +Option C: It acts as a competitive alpha-3-beta-4-nicotinic antagonist. +Option D: It is a selective alpha-1a adrenergic antagonist. +" C +6918314 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +Option B: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor. +" A +3001055 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN/C(=C\\[N+](=O)[O-])/NCCSCC1=CC=C(O1)CN(C)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a histamine type 2 receptor antagonist (H2 blocker). +Option B: It is a second-generation histamine H1 antagonist. +Option C: It is a H1 histamine receptor antagonist. +Option D: It is a histamine H1 antagonist. +" A +2564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It antagonizes the effects of histamine on HA-receptors. +Option B: It is a potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor. +Option C: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +Option D: It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor. +" A +54746 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)CC=C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonin receptor agonist. +Option B: It is a melatonin receptor agonist. +Option C: It is a prolactin inhibitor. +Option D: It is a selective serotonin agonist. +" C +5403 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a beta-3 adrenergic agonist. +Option B: It is a non-selective beta adrenergic receptor agonist. +Option C: It is an agonist at a2-adrenergic receptor sites. +Option D: It is a selective beta-2 adrenergic agonist. +" D +2370 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C[N+](C)(C)C)OC(=O)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a slowly hydrolyzed muscarinic agonist. +Option B: It is a long-acting muscarinic antagonist (LAMA). +Option C: It is a muscarinic agonist. +Option D: It is a muscarinic antagonist. +" C +27400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a serotonin receptor agonist. +Option B: It is a serotonin antagonist. +Option C: It is a serotonin and tryptamine antagonist. +Option D: It is a serotonergic antagonist. +" C +129211 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=CC=CC=C1OCCN[C@H](C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an alpha-adrenergic antagonist. +Option B: It is a selective alpha-1a adrenergic antagonist. +Option C: It is a beta-adrenergic antagonist. +Option D: It is an adrenergic antagonist. +" B +16078 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC(=C2[C@@H]3C=C(CC[C@H]3C(OC2=C1)(C)C)C)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is an Opioid Antagonist. +Option B: It is an alpha-adrenergic antagonist. +Option C: It is an orally available cannabinoid agonist. +Option D: It is an adrenergic antagonist. +" C +2678 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCOCC(=O)O)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1 histamine receptor antagonist. +Option B: It is a second-generation histamine H1 antagonist. +Option C: It is a histamine antagonist. +Option D: It is a histamine H1 antagonist. +" B +5419 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(C2=CC=CC=C2C1)C3=NCCN3 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a selective beta-2 adrenergic agonist. +Option B: It is a long acting beta-adrenoceptor agonist. +Option C: It is a selective α1-receptor agonist. +Option D: It is a selective β3 adrenoceptor agonist. +" C +11519070 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[N+]2(CCC1(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)CCOCC5=CC=CC=C5 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a muscarinic antagonist and a histamine antagonist. +Option B: It is a long-acting muscarinic antagonist (LAMA). +Option C: It is a H1-receptor antagonist and a muscarinic antagonist. +Option D: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist. +" B +3033637 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN/C(=C\\[N+](=O)[O-])/NCCSCC1=CSC(=N1)CN(C)C +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a H1 histamine receptor antagonist. +Option B: It is a histamine type 2 receptor antagonist (H2 blocker). +Option C: It is a second-generation histamine H1 antagonist. +Option D: It is a histamine H1 antagonist. +" B +3779 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(C1=CC(=C(C=C1)O)O)O +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a nonselective alpha-adrenergic antagonist (alpha-blocker). +Option B: It is a non-opioid centrally acting alpha2-adrenergic receptor agonist. +Option C: It is a nonselective alpha-1 adrenergic antagonist (alpha-blocker). +Option D: It is a non-selective beta adrenergic receptor agonist. +" D +135413536 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=C(C=C4)F +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a substance P/neurokinin 1 (NK1) receptor antagonist. +Option B: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. +Option C: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist. +Option D: It is a Substance P/Neurokinin-1 Receptor Antagonist. +" A +4168 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a dopaminergic antagonist. +Option B: It is a dopamine receptor D2 antagonist. +Option C: It is a dopamine antagonist. +Option D: It is a histamine antagonist. +" C +47811 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN1C[C@@H](C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)CSC +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a long-acting dopamine agonist. +Option B: It is a selective dopamine receptor agonist. +Option C: It is a dopamine receptor D2 antagonist. +Option D: It is a non-ergoline dopamine D2 agonist. +" A +2284 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(CC(=O)O)CN)Cl +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a gamma-aminobutyric acid (GABA) agonist. +Option B: It is a slowly hydrolyzed muscarinic agonist. +Option C: It is a muscarinic agonist. +Option D: It is a muscarinic antagonist. +" A +3100 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2 +Question about this molecule: Which kind of antagonist is this molecule? +Option A: It is a histamine H1 antagonist. +Option B: It is a histamine antagonist. +Option C: It is a second-generation histamine H1 antagonist. +Option D: It is a H1 histamine receptor antagonist. +" A +165580 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. +Option B: It is an antibacterial drug used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections and against visceral leishmaniasis. +Option C: It is used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +Option D: It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. +" B +71260 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)(C)F)C)O)(C)O +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial agent used as an ingredient in toothpastes. +Option B: It is an antibacterial agent used for veterinary use against bacterial infections. +Option C: It has been used (generally as the corresponding monoethyl succinate ester) as an antibacterial drug. +Option D: It is a metabolite, an antibacterial agent, and an antineoplastic agent. +" C +6435927 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]([C@@H](O)C)[C@@H]1O[C@H]1C[C@@H]2[C@H]([C@H]([C@@H](OC2)C/C(=C/C(=O)OCCCCCCCCC(=O)[O-])/C)O)O.C[C@@H]([C@@H](O)C)[C@@H]1O[C@H]1C[C@@H]2[C@H]([C@H]([C@@H](OC2)C/C(=C/C(=O)OCCCCCCCCC(=O)[O-])/C)O)O.[Ca+2] +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial agent used for veterinary use against bacterial infections. +Option B: It is used as an antibacterial drug for the treatment of skin infections. +Option C: It is an antibacterial agent used as an ingredient in toothpastes. +Option D: It is an antibacterial agent with antibacterial activity. +" B +9835049 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)O)C(=O)N +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial drug used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections and against visceral leishmaniasis. +Option B: The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. +Option C: It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. +Option D: It is used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +" D +13755 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial agent used for veterinary use against bacterial infections. +Option B: It is an antibacterial agent used as an ingredient in toothpastes. +Option C: It is an antibacterial agent with antibacterial activity. +Option D: It is used as an antibacterial drug for the treatment of skin infections. +" A +5281006 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C/C1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. +Option B: The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. +Option C: It is used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +Option D: It is used to treat bronchitis as well as ear, skin and other bacterial infections. +" D +5362065 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\\OCC(=O)O)/C3=CSC(=N3)N)SC1)C(=O)O +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial drug used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections and against visceral leishmaniasis. +Option B: The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. +Option C: It is used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +Option D: It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. +" D +9863776 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C/C=C\\C(=O)[C@H]([C@H](C/C=C/C2=C(C(=CC(=C2)OC)O)C(=O)O1)O)O +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is a metabolite and an antibacterial agent. +Option B: It is an antibacterial agent used as an ingredient in toothpastes. +Option C: It is a metabolite, an antibacterial agent, and an antineoplastic agent. +Option D: It is an antibacterial agent used for veterinary use against bacterial infections. +" C +5564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is used as an antibacterial drug for the treatment of skin infections. +Option B: It is an antibacterial agent used for veterinary use against bacterial infections. +Option C: It is widely used as a preservative and antimicrobial agent in personal care products and household items. +Option D: A lipophilic antibacterial drug mainly used in spray dosage forms for the local treatment of infection and inflammation of the throat. +" C +10696525 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C/C=C/C=C/C(=O)NC1=C[C@]([C@H]2[C@@H](C1=O)O2)(/C=C/C=C/C=C/C(=O)NC3=C(CCC3=O)O)O +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial agent used as an ingredient in toothpastes. +Option B: It is an antibacterial agent with antibacterial activity. +Option C: It is an antibacterial agent used for veterinary use against bacterial infections. +Option D: It is a metabolite and an antibacterial agent. +" D +44241698 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=C)[C@@H]1CC=C2C[C@@](CC[C@@H]2[C@@]1(C)CCC(=O)O)(C)C=C +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is a metabolite and an antibacterial agent. +Option B: It is an antibacterial agent with antibacterial activity. +Option C: It is an antibacterial agent used for veterinary use against bacterial infections. +Option D: It is an antibacterial agent used as an ingredient in toothpastes. +" A +24266 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [O-]P(=O)([O-])F.[Na+].[Na+] +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial agent with antibacterial activity. +Option B: It is an antibacterial agent used as an ingredient in toothpastes. +Option C: It is a metabolite and an antibacterial agent. +Option D: It is an antibacterial agent used for veterinary use against bacterial infections. +" B +11471955 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C=C1Br)[C@@]2(CC[C@H]3[C@@]2(C3)C)C)O +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: It is an antibacterial agent used as an ingredient in toothpastes. +Option B: It is a metabolite and an antibacterial agent. +Option C: It is an antibacterial agent with antibacterial activity. +Option D: It is an antibacterial agent used for veterinary use against bacterial infections. +" C +53469 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1)Cl)Cl)NC(=O)C2=C(C(=C(C(=C2Cl)Cl)Cl)Cl)C(=O)O +Question about this molecule: How can the molecule be used as a/an antibacterial drug +Option A: A lipophilic antibacterial drug mainly used in spray dosage forms for the local treatment of infection and inflammation of the throat. +Option B: It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. +Option C: It is used for the treatment of bacterial leaf blight in paddy rice. +Option D: It is used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +" C +6604200 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-] +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an Oxazolidinone Antibacterial. +Option B: It is a Nitrofuran Antibacterial. +Option C: It is a synthetic fluoroquinolone antibacterial agent. +Option D: It is a Fluoroquinolone Antibacterial. +" B +152946 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Fluoroquinolone Antibacterial. +Option B: It is a synthetic fluoroquinolone antibacterial agent. +Option C: It is a Nitrofuran Antibacterial. +Option D: It is an Oxazolidinone Antibacterial. +" A +2993 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=[N+](C2=CC=CC=C2C(=C1)N)CCCCCCCCCC[N+]3=C(C=C(C4=CC=CC=C43)N)C +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial agent with multi-targeted actions. +Option B: It is an antibacterial and antifungal agent. +Option C: It is an antibacterial in the sulfonamide class. +Option D: It is a synthetic antibacterial compound. +" A +5320 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NS(=O)(=O)C1=CC=C(C=C1)N +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial in the sulfonamide class. +Option B: It is a Rifamycin Antibacterial. +Option C: It is one of the sulfa drugs. +Option D: It is a Sulfonamide Antibacterial. +" D +9870843 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(SC=N1)/C=C\\C2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\\OC)/C4=CSC(=N4)N)SC2)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Cephalosporin Antibacterial. +Option B: It is a Nitrofuran Antibacterial. +Option C: It is a Penem Antibacterial. +Option D: It is a Rifamycin Antibacterial. +" A +9938701 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCO/N=C(/C1=NSC(=N1)N)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)[O-] +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Nitrofuran Antibacterial. +Option B: It is a Rifamycin Antibacterial. +Option C: It is a Cephalosporin Antibacterial. +Option D: It is a Penem Antibacterial. +" C +5284585 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=C(N2[C@H]1[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Cephalosporin Antibacterial. +Option B: It is a Rifamycin Antibacterial. +Option C: It is a Penem Antibacterial. +Option D: It is a Nitrofuran Antibacterial. +" A +104838 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Rifamycin Antibacterial. +Option B: It is a Nitrofuran Antibacterial. +Option C: It is a Cephalosporin Antibacterial. +Option D: It is a Penem Antibacterial. +" D +47965 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Rifamycin Antibacterial. +Option B: It is a Penem Antibacterial. +Option C: It is a Cephalosporin Antibacterial. +Option D: It is a Nitrofuran Antibacterial. +" C +51039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Rifamycin Antibacterial. +Option B: It is a Penem Antibacterial. +Option C: It is a Cephalosporin Antibacterial. +Option D: It is a Nitrofuran Antibacterial. +" C +5742673 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\\OC)/C3=CSC(=N3)N)SC1)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Rifamycin Antibacterial. +Option B: It is a Cephalosporin Antibacterial. +Option C: It is a Penem Antibacterial. +Option D: It is a Nitrofuran Antibacterial. +" B +2722 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C(=C(C=C2Cl)Cl)O)N=C1 +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial in the sulfonamide class. +Option B: It is a synthetic antibacterial compound. +Option C: It is an antibacterial and antifungal agent. +Option D: It is an antibacterial agent with multi-targeted actions. +" B +3468 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1=CC=C(C=C1)C(=C2C=CC(=[N+](C)C)C=C2)C3=CC=C(C=C3)N(C)C +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. +Option B: It is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria. +Option C: It is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB). +Option D: It is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties. +" D +441244 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Ag+] +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial in the sulfonamide class. +Option B: It is a Rifamycin Antibacterial. +Option C: It is one of the sulfa drugs. +Option D: It is a Sulfonamide Antibacterial. +" D +5564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial and antifungal agent. +Option B: It is an antibacterial agent with multi-targeted actions. +Option C: It is an antibacterial in the sulfonamide class. +Option D: It is a synthetic antibacterial compound. +" A +6335986 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\\OC)/C3=CSC(=N3)N)SC1)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Rifamycin Antibacterial. +Option B: It is a Nitrofuran Antibacterial. +Option C: It is a Cephalosporin Antibacterial. +Option D: It is a Penem Antibacterial. +" C +27447 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)SC1)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Cephalosporin Antibacterial. +Option B: It is a Penem Antibacterial. +Option C: It is a Nitrofuran Antibacterial. +Option D: It is a Rifamycin Antibacterial. +" A +1046 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=C(C=N1)C(=O)N +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB). +Option B: It is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties. +Option C: It is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. +Option D: It is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria. +" A +36294 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Fluoroquinolone Antibacterial. +Option B: It is an Oxazolidinone Antibacterial. +Option C: It is an Aminoglycoside Antibacterial. +Option D: It is a synthetic fluoroquinolone antibacterial agent. +" C +5578 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Cephalosporin Antibacterial. +Option B: It is a RNA Synthetase Inhibitor Antibacterial. +Option C: It is a Penem Antibacterial. +Option D: It is a Dihydrofolate Reductase Inhibitor Antibacterial. +" D +2764 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Nitrofuran Antibacterial. +Option B: It is an Oxazolidinone Antibacterial. +Option C: It is a Fluoroquinolone Antibacterial. +Option D: It is a synthetic fluoroquinolone antibacterial agent. +" C +7547 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1NC(=O)NC2=CC(=C(C=C2)Cl)Cl)Cl +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. +Option B: It is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria. +Option C: It is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties. +Option D: It is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB). +" A +37768 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)O)N +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an Aminoglycoside Antibacterial. +Option B: It is a Fluoroquinolone Antibacterial. +Option C: It is an Oxazolidinone Antibacterial. +Option D: It is a synthetic fluoroquinolone antibacterial agent. +" A +5362065 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\\OCC(=O)O)/C3=CSC(=N3)N)SC1)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Rifamycin Antibacterial. +Option B: It is a Nitrofuran Antibacterial. +Option C: It is a Penem Antibacterial. +Option D: It is a Cephalosporin Antibacterial. +" D +3198 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It has some action against Gram positive bacteria. +Option B: It is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria. +Option C: It is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. +Option D: It is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties. +" A +6915944 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\\O)/C3=CSC(=N3)N)SC1)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Cephalosporin Antibacterial. +Option B: It is a Nitrofuran Antibacterial. +Option C: It is a Penem Antibacterial. +Option D: It is a Rifamycin Antibacterial. +" A +6533629 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CO/N=C(/C1=CSC(=N1)N)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=CCS3)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Cephalosporin Antibacterial. +Option B: It is a Rifamycin Antibacterial. +Option C: It is a Penem Antibacterial. +Option D: It is a Nitrofuran Antibacterial. +" A +6115 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)N +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Sulfonamide Antibacterial. +Option B: It is a Rifamycin Antibacterial. +Option C: It is one of the sulfa drugs. +Option D: It is an antibacterial in the sulfonamide class. +" C +5282242 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\\CC(=O)O)/C3=CSC(=N3)N)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Nitrofuran Antibacterial. +Option B: It is a Penem Antibacterial. +Option C: It is a Rifamycin Antibacterial. +Option D: It is a Cephalosporin Antibacterial. +" D +33255 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NN=C(S1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Cephalosporin Antibacterial. +Option B: It is a Nitrofuran Antibacterial. +Option C: It is a Rifamycin Antibacterial. +Option D: It is a Penem Antibacterial. +" A +5215 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Sulfonamide Antibacterial. +Option B: It is an antibacterial in the sulfonamide class. +Option C: It is one of the sulfa drugs. +Option D: It is a Rifamycin Antibacterial. +" A +4189 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB). +Option B: It is an antibacterial agent that is particularly effective against Gram-positive bacteria such as Staphylococcus aureus. +Option C: It is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria. +Option D: It is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties. +" C +53025 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)C4SC(=C(C(=O)N)C(=O)O)S4)OC)SC2)C(=O)O +Question about this molecule: Which kind of antibacterial drug is this molecule? +Option A: It is a Penem Antibacterial. +Option B: It is a Cephalosporin Antibacterial. +Option C: It is a Rifamycin Antibacterial. +Option D: It is a Nitrofuran Antibacterial. +" B +54675779 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial agent and an antimicrobial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antimicrobial agent and an antibacterial agent. +Option D: It can be used as an antibacterial drug and a protein synthesis inhibitor. +" D +10482623 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C/C=C/C=C\\CCC(=C)CC(C)C/C(=C/C(=O)O)/C)CC(=O)CC(CNC(=O)C(C)C(C)OC(=O)N)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is a bacterial metabolite and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It exhibits antibacterial activity. +Option D: It is an antibiotic with antibacterial activity. +" D +56206 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used primarily to treat infections caused by Gram-negative bacteria. +Option B: It has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. +Option C: It is a broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria. +Option D: Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. +" C +21141346 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C(C=CC2=C1O[C@@H]3[C@H]2COC4=C3C=CC(=C4CC=C(C)C)O)O)C +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It exhibits antibacterial activity. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antibiotic with antibacterial activity. +Option D: It is a bacterial metabolite and an antibacterial agent. +" A +9938701 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCO/N=C(/C1=NSC(=N1)N)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)[O-] +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antimicrobial agent and an antiinfective agent. +Option C: It is an antibacterial drug and an antimicrobial agent. +Option D: It is an antibacterial agent and an antimicrobial agent. +" C +3218 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCC1=C(C(=O)C=C(C1=O)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antimicrobial agent and an antibacterial agent. +Option D: It exhibits antimicrobial activity. +" D +6444314 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C/C=C/C=C/CCC(=C)CC(C)C/C(=C/C(=O)O)/C)CC(=O)CC(CNC(=O)C(C)C(C)OC(=O)N)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It exhibits antibacterial activity. +Option B: It is an antibiotic with antibacterial activity. +Option C: It is a bacterial metabolite and an antibacterial agent. +Option D: It is an antibacterial drug and an antimicrobial agent. +" B +29327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is a synthetic veterinary antibiotic and an antimicrobial agent. +Option B: It is an antibiotic, immunosupressive and antineoplastic agent. +Option C: It is a Penicillium metabolite and an antimicrobial agent. +Option D: It is an antibiotic produced by Streptomyces achromogenes. +" D +14969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antibacterial drug derived from a vancomycin aglycone. +Option D: It is an antibacterial agent and an antimicrobial agent. +" C +10052850 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C/C=C/C=C\\CCC(=C)CC(C)C/C(=C/C(=O)O)/C)CC(=O)CC(CNC(=O)CC(C)OC(=O)N)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial drug and an antimicrobial agent. +Option B: It is an antibiotic with antibacterial activity. +Option C: It exhibits antibacterial activity. +Option D: It is a bacterial metabolite and an antibacterial agent. +" B +6324633 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N)N +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial agent and an antimicrobial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" C +53262842 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCC/C=C/[C@H](C(=O)N[C@@H](CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)[C@@H](/C=C/CC/C=C(\\C)/CCCCCC)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent. +Option B: It is a Penicillium metabolite and an antimicrobial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" B +9884187 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H]1CC2=CC(=C3C(=C2C(=O)C1)C(=O)C4=C(C3=O)C(=CC=C4)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial agent and an antimicrobial agent. +Option B: It is an antimicrobial agent and an antiinfective agent. +Option C: It is an antimicrobial agent and an antibacterial agent. +Option D: It is an antibacterial drug and an antimicrobial agent. +" A +66895 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1N=NC2=C(C=C(C=C2)N)N)S(=O)(=O)N +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent and an antiinfective agent. +" B +15541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC(=O)[C@]2([C@@H](O1)O[C@@H]3[C@H]([C@@H]([C@@H]([C@@H]([C@H]3O2)NC)O)NC)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. +Option B: It is effective against gram-negative and gram-positive organisms. +Option C: It displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. +Option D: It is active against gram-negative bacteria and used to treat gonorrhea. +" D +10473054 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H]1CC2=CC(=C3C(=C2C(=O)C1)C(=O)C4=C(C3=O)C(=CC=C4)OC)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antibacterial drug and an antimicrobial agent. +Option D: It is an antimicrobial agent and an antiinfective agent. +" B +54675769 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)O)CC=C(C)C)O[C@H]4[C@@H]([C@@H]([C@H](C(O4)(C)C)OC)OC(=O)N)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antimicrobial agent and an antiinfective agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antibacterial drug and an antimicrobial agent. +" C +5327150 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC=[N+]1CC2=CN=C(N=C2N)C)CCOP(=O)(O)OP(=O)(O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial agent and an antimicrobial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antimicrobial agent and an antibacterial agent. +Option D: It is an antimicrobial agent. +" D +114811 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)C1=CC=C(C=C1)[C@H]([C@@H](CF)NC(=O)C(Cl)Cl)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is a synthetic veterinary antibiotic and an antimicrobial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antimicrobial agent and an antibacterial agent. +Option D: It is an antibacterial drug and an antimicrobial agent. +" A +207889 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O)N +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antimicrobial agent and an antibacterial agent. +Option D: It is an antibacterial drug and an antimicrobial agent. +" A +12302172 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O)O[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antimicrobial agent and an antibacterial agent. +Option D: It is an antibacterial agent and an antimicrobial agent. +" A +46174033 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCNC(=O)CC[C@@H](C(=O)O)N)O)O)O[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial drug and an antimicrobial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" C +33344 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=O)C=C(S1)Cl +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent. +Option B: It is an antimicrobial agent and an antibacterial agent. +Option C: It is an antibacterial drug and an antimicrobial agent. +Option D: It is an antibacterial agent and an antimicrobial agent. +" A +446987 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H](O1)P(=O)(O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial agent and an antimicrobial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" C +9905162 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@@H]([C@@H]2[C@H]([C@H](C=CC2=C1)C)CC[C@@H]3C[C@H](CC(=O)O3)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent. +" D +12302171 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O)O[C@H]2[C@@H]([C@H]([C@H](O2)CO)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent. +" D +23675312 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CSC3=CC=NC=C3)SC1)C(=O)[O-].[Na+] +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. +Option B: Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. +Option C: It is active against gram-negative bacteria and used to treat gonorrhea. +Option D: It is effective against gram-negative and gram-positive organisms. +" D +9812715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCNCCN[C@]1(C[C@@H](O[C@H]([C@H]1O)C)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C(=C(C=C9[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)O)CNCP(=O)(O)O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)C.Cl +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA. +Option B: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +Option C: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option D: Used for treatment of adults with complicated skin and skin structure infections caused by bacteria. +" D +4022878 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.[Na+] +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antiinfective agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" A +54684461 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective. +Option B: It is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. +Option C: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option D: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +" B +86583456 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)[C@H]2[C@@H]([C@@H]1C[C@@H](C(=O)[O-])[NH3+])O2 +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial drug and an antimicrobial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" C +23663400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+] +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option B: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option C: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +Option D: Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +" B +5284585 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=C(N2[C@H]1[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)O)Cl +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option B: It displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. +Option C: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option D: Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. +" D +54680690 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option B: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option C: It is used for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective. +Option D: It is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. +" C +23665591 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]2N(C1=O)[C@H](/C(=C/CO)/O2)C(=O)[O-].[K+] +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option B: Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +Option C: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option D: It is used in combination with amoxicillin trihydrate for treatment of a variety of bacterial infections, where it prevents antibiotic inactivation by microbial lactamases. +" D +54686904 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(=O)NC1=CC(=C2C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria. +Option B: It has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. +Option C: It is used for the treatment of acute bacterial skin and skin structure infections caused or suspected to be caused by susceptible isolates of designated Gram-positive microorganisms including MRSA. +Option D: It displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. +" B +64740 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC(=O)[C@]2([C@@H](O1)O[C@@H]3[C@H]([C@@H]([C@@H]([C@@H]([C@H]3O2)NC)O)NC)O)O.Cl.Cl +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used (as its pentahydrate) to treat gonorrhea. +Option B: It is active against gram-negative bacteria and used to treat gonorrhea. +Option C: It is used for the treatment of invasive candidiasis. +Option D: It is effective against gram-negative and gram-positive organisms. +" A +11594149 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCCC#CCCCCCCCCCCC(=O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It exhibits antibacterial activity. +Option B: It is a bacterial metabolite and an antibacterial agent. +Option C: It exhibits antimycobacterial and antiplasmodial activities. +Option D: It is an antibiotic with antibacterial activity. +" C +9835049 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)O)C(=O)N +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option B: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option C: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +Option D: Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +" D +4173 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CCO)[N+](=O)[O-] +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option B: Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +Option C: It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. +Option D: It displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. +" C +11794029 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H](C)C1=CC(=O)C2=C(O1)C3=C(C=C2CO)C(=O)C4=C(C3=O)C(=CC=C4)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +Option B: It exerts a potent protecting effect on neuronal cells through suppressing L-glutamate toxicity. +Option C: It displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia. +Option D: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +" B +6324616 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1/C=C/C=C(\\C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It exhibits antibiotic and antitubercular properties. +Option B: It induces apoptosis and displays antitumour effects. +Option C: It is an antibiotic produced by Streptomyces achromogenes. +Option D: It exhibits antibiotic and antitumour properties. +" A +54680675 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)NCO)N(C)C)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option B: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option C: Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis. +Option D: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +" B +68624 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O.Cl +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +Option B: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option C: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +Option D: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. +" D +54671203 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. +Option B: It is used for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective. +Option C: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option D: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +" A +56927837 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCC/C=C/C(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C)C[C@H]([C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial drug and an antimicrobial agent. +Option B: It is an antimicrobial agent and an antibacterial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent. +" D +56927848 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CCCCCCC/C=C/C(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C)C[C@H]([C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial agent and an antimicrobial agent. +Option B: It is an antimicrobial agent and an antibacterial agent. +Option C: It is an antimicrobial agent. +Option D: It is an antibacterial drug and an antimicrobial agent. +" C +56927841 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CCCCCCCCCCC/C=C/C(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C)C[C@H]([C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial drug and an antimicrobial agent. +Option B: It is an antimicrobial agent and an antibacterial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent. +" D +5311102 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=O)C=C([C@@H]1OC)C2=O)/C)OC)OC(=O)N)\\C)C)OC)OC +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It induces apoptosis and displays antitumour effects. +Option B: It is an antibiotic produced by Streptomyces achromogenes. +Option C: It exhibits antibiotic and antitumour properties. +Option D: It exhibits antibiotic and antitubercular properties. +" A +19150 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)SC1)C(=O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antimicrobial agent. +Option D: It is an antibacterial agent and an antimicrobial agent. +" C +56927832 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CCCCCCCC/C=C/C(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C)C[C@H]([C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antimicrobial agent. +Option D: It is an antibacterial agent and an antimicrobial agent. +" C +11489675 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CC[C@H]([C@H]([C@H](CO)O)O)O)[C@H]1CC[C@]2([C@H]1CC[C@@]3([C@@H]2CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CCCC5(C)C)C)C)C)C +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antibacterial agent and an antimicrobial agent. +Option B: It is a Penicillium metabolite and an antimicrobial agent. +Option C: It is a lipoxygenase inhibitor, a bacterial metabolite, and an antimicrobial agent. +Option D: It is an antibacterial drug and an antimicrobial agent. +" C +9828474 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCN)CCN(C(=O)CCC(=O)NCCCCCN(C(=O)CCC(=O)NCCCCC[N+](=O)[O-])O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent and an antibacterial agent. +Option B: It is an antibacterial drug and an antimicrobial agent. +Option C: It is an antibacterial agent and an antimicrobial agent. +Option D: It is an antimicrobial agent. +" D +5281828 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)C)C)\\C)OC)(NC(=O)O2)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antibacterial drug and an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" A +56927835 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CCCCCCCCCCCC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(=O)C)C[C@H]([C@@H]3[C@H]([C@H]([C@@H](O3)N4C=CC(=O)NC4=O)O)O)O)O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is an antimicrobial agent. +Option B: It is an antibacterial agent and an antimicrobial agent. +Option C: It is an antibacterial drug and an antimicrobial agent. +Option D: It is an antimicrobial agent and an antibacterial agent. +" A +28061 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CC(CCl)O)[N+](=O)[O-] +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +Option B: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. +Option C: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option D: It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections. +" D +5284616 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is a synthetic veterinary antibiotic and an antimicrobial agent. +Option B: It is an antibiotic produced by Streptomyces achromogenes. +Option C: It is a Penicillium metabolite and an antimicrobial agent. +Option D: It is an antibiotic, immunosupressive and antineoplastic agent. +" D +3948 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. +Option B: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option C: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +Option D: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia. +" C +6634 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1N)S(=O)(=O)NC2=NN=C(C=C2)Cl +Question about this molecule: How can the molecule be used as a/an antibiotic +Option A: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. +Option B: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. +Option C: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. +Option D: It is used for urinary tract infections and in veterinary medicine. +" D +54675783 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections. +Option B: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms. +Option C: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option D: It is a carbapenem antibiotic with broad spectrum of activity administered intravenously and used for severe bacterial infections due to sensitive agents. +" C +6604200 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-] +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. +Option B: It is a broad spectrum antibiotic used for uncomplicated urinary tract infections. +Option C: It is a lincosamide antibiotic used for serious infections and topically for acne vulgaris. +Option D: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +" A +6032 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a bactericidal aminoglycoside antibiotic. +Option B: It is a broad spectrum aminoglycoside antibiotic. +Option C: It is an aminoglycoside antibiotic. +Option D: It is an aminoglycoside bacteriocidal antibiotic used to treat a wide variety of infections. +" D +5959 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +Option B: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option C: It is a broad spectrum antibiotic that was shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available. +Option D: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +" C +5481173 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C(=O)O)O/N=C(/C1=CSC(=N1)N)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-] +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option B: It is a cephalosporin antibiotic commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others. +Option C: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +Option D: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +" C +71141 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSC[C@H](C(=O)O)N)OC)SC2)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a second generation cephalosporin antibiotic. +Option B: It is a broad-spectrum cephalosporin antibiotic. +Option C: It is a third-generation cephalosporin antibiotic. +Option D: It is a novel broad-spectrum and third-generation cephalosporin antibiotic. +" A +5280440 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H]1[C@H](/C=C(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)\\C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. +Option B: It is a lincosamide antibiotic used for serious infections and topically for acne vulgaris. +Option C: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option D: It is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. +" D +5742673 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\\OC)/C3=CSC(=N3)N)SC1)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a novel broad-spectrum and third-generation cephalosporin antibiotic. +Option B: It is a third-generation cephalosporin antibiotic. +Option C: It is a broad-spectrum cephalosporin antibiotic. +Option D: It is a second generation cephalosporin antibiotic. +" B +30323 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is an anthracycline antibiotic that has antineoplastic activity and is used in the therapy of acute leukemia and AIDS related Kaposi sarcoma. +Option B: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option C: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +Option D: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +" A +19649 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +Option B: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option C: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +Option D: It is a cephalosporin antibiotic commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others. +" B +3948 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a second generation fluoroquinolone antibiotic used in the therapy of mild-to-moderate urinary and respiratory tract infections caused by susceptible organisms. +Option B: It is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). +Option C: It is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. +Option D: It is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA). +" B +62959 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]2[C@@H](C2N)CN1C3=C(C=C4C(=O)C(=CN(C4=N3)C5=C(C=C(C=C5)F)F)C(=O)O)F +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option B: It is a broad spectrum antibiotic used as a second line agent for drug resistant tuberculosis. +Option C: It is a broad spectrum antibiotic that has been commonly marketed under the brand name Trovan by Pfizer. +Option D: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +" C +5329 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. +Option B: It is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. +Option C: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option D: It is a lincosamide antibiotic used for serious infections and topically for acne vulgaris. +" B +30699 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)CSC3=CC=NC=C3)SC1)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a novel broad-spectrum and third-generation cephalosporin antibiotic. +Option B: It is a first-generation cephalosporin antibiotic that is available in injectable formulations. +Option C: It is a third-generation cephalosporin antibiotic. +Option D: It is a second generation cephalosporin antibiotic. +" B +18381 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is an oral, second generation penicillin antibiotic used to treat bacterial infections caused by penicillinase-resistant staphylococci. +Option B: It is a parenteral, second generation penicillinase-resistant penicillin antibiotic used largely to treat moderate to severe staphylococcal infections. +Option C: It is a second generation penicillin antibiotic used for penicillinase-resistant staphylococcal infections. +Option D: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms. +" A +6335986 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COCC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)/C(=N\\OC)/C3=CSC(=N3)N)SC1)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option B: It is a cephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus. +Option C: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +Option D: It is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. +" D +54680675 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)NCO)N(C)C)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a tetracycline used to treat bacterial infections. +Option B: It is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections. +Option C: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option D: It is a glycycline antibiotic used for serious infections. +" A +15541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC(=O)[C@]2([C@@H](O1)O[C@@H]3[C@H]([C@@H]([C@@H]([C@@H]([C@H]3O2)NC)O)NC)O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +Option B: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +Option C: It is active against gram-negative bacteria and used for the treatment of gonorrhea. +Option D: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +" C +54671203 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. +Option B: It is a semisynthetic macrolide antibiotic commonly used for a wide variety of mild-to-moderate bacterial infections. +Option C: It is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. +Option D: It is a semisynthetic, tetracycline related bacteriostatic antibiotic. +" D +36294 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H](C[C@@H]([C@H](O3)CN)O)N)N +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a carbapenem antibiotic with broad spectrum of activity administered intravenously and used for severe bacterial infections due to sensitive agents. +Option B: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option C: It is a broad spectrum antibiotic that was shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available. +Option D: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms. +" D +54707177 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCNCCCC[C@@H](C(=O)O)N)N(C)C)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections. +Option B: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms. +Option C: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option D: It is a carbapenem antibiotic with broad spectrum of activity administered intravenously and used for severe bacterial infections due to sensitive agents. +" A +4173 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CCO)[N+](=O)[O-] +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a quinolone derivative antibiotic used for various bacterial infections. +Option B: It is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. +Option C: It is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. +Option D: It is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). +" C +9852981 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCO/N=C(/C1=NSC(=N1)NP(=O)(O)O)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)[O-] +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +Option B: It is a cephalosporin antibacterial indicated for the treatment of acute bacterial skin and skin structure infections. +Option C: It is a cephalosporin antibiotic commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others. +Option D: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +" B +2764 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). +Option B: It is a second generation fluoroquinolone antibiotic used in the therapy of mild-to-moderate urinary and respiratory tract infections caused by susceptible organisms. +Option C: It is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. +Option D: It is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA). +" B +5281006 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C/C1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)SC1)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +Option B: It is a cephalosporin antibiotic commonly employed to treat a variety of bacterial infections, including those of the ear and skin, bronchitis, and others. +Option C: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa. +Option D: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +" B +5144 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCC1=CC2=C(C=C1)OCO2 +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a novel broad-spectrum and third-generation cephalosporin antibiotic. +Option B: It exhibits antibiotic and anti-angiogenic functions. +Option C: It is a first-generation cephalosporin antibiotic that is available in injectable formulations. +Option D: It is a third-generation cephalosporin antibiotic. +" B +54680690 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. +Option B: It is a third-generation antibiotic agent used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia. +Option C: It is a semisynthetic tetracycline derived from Streptococcus aureofaciens used as an antibiotic and an inhibitor of arginine vasopressin in the therapy of hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). +Option D: It is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA). +" C +37768 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)O)N +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is an aminoglycoside bacteriocidal antibiotic used to treat a wide variety of infections. +Option B: It is an aminoglycoside antibiotic. +Option C: It is a broad spectrum aminoglycoside antibiotic. +Option D: It is a bactericidal aminoglycoside antibiotic. +" C +5904 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad-spectrum cephalosporin antibiotic. +Option B: It is a broad spectrum carbapenem antibiotic. +Option C: It is a narrow spectrum antibiotic. +Option D: It is a broad spectrum aminoglycoside antibiotic. +" C +4679 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is used to treat H. pylori infections along with other antibiotics. +Option B: It is an antibiotic used in maggot therapy and added to cigarettes for aroma. +Option C: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option D: It is used in combination with other antibiotics. +" A +446987 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H](O1)P(=O)(O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad spectrum antibiotic used for uncomplicated urinary tract infections. +Option B: It is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. +Option C: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option D: It is a lincosamide antibiotic used for serious infections and topically for acne vulgaris. +" A +9571107 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CO/N=C/1\\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a second generation fluoroquinolone antibiotic used in the therapy of mild-to-moderate urinary and respiratory tract infections caused by susceptible organisms. +Option B: It is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. +Option C: It is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). +Option D: It is a fourth generation fluoroquinolone antibiotic used for respiratory tract infections. +" D +998 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CC=O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a third-generation cephalosporin antibiotic. +Option B: It is an antibiotic used in maggot therapy and added to cigarettes for aroma. +Option C: It is a first-generation cephalosporin antibiotic that is available in injectable formulations. +Option D: It is a novel broad-spectrum and third-generation cephalosporin antibiotic. +" B +6234 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H](C(=O)NO1)N +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a broad spectrum antibiotic used as a second line agent for drug resistant tuberculosis. +Option B: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents. +Option C: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis. +Option D: It is a broad spectrum antibiotic that was shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available. +" A +6196 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a second generation penicillin antibiotic used for penicillinase-resistant staphylococcal infections. +Option B: It is a parenteral, second generation penicillinase-resistant penicillin antibiotic used largely to treat moderate to severe staphylococcal infections. +Option C: It is an oral, second generation penicillin antibiotic used to treat bacterial infections caused by penicillinase-resistant staphylococci. +Option D: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms. +" A +439530 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is an antibiotic that prevents bacterial protein translation. +Option B: It is an antibiotic used in maggot therapy and added to cigarettes for aroma. +Option C: It is used to treat H. pylori infections along with other antibiotics. +Option D: It is used in combination with other antibiotics. +" A +54686904 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(=O)NC1=CC(=C2C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne. +Option B: It is a tetracycline used to treat bacterial infections. +Option C: It is a glycycline antibiotic used for serious infections. +Option D: It is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections. +" C +8378 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a bactericidal aminoglycoside antibiotic. +Option B: It is an aminoglycoside bacteriocidal antibiotic used to treat a wide variety of infections. +Option C: It is an aminoglycoside antibiotic. +Option D: It is a broad spectrum aminoglycoside antibiotic. +" A +5282242 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)/C(=C\\CC(=O)O)/C3=CSC(=N3)N)C(=O)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a novel broad-spectrum and third-generation cephalosporin antibiotic. +Option B: It is a broad-spectrum cephalosporin antibiotic. +Option C: It is a third-generation cephalosporin antibiotic. +Option D: It is a second generation cephalosporin antibiotic. +" C +71188 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is an antibiotic agent from the fluoroquinolone family. +Option B: It is a fluoroquinolone antibiotic used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). +Option C: It is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections. +Option D: It is a fourth generation fluoroquinolone antibiotic used for respiratory tract infections. +" A +5284616 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a glycopeptide antibiotic. +Option B: It is a narrow spectrum antibiotic. +Option C: It is a macrocyclic antibiotic. +Option D: It is a macrolide glycopeptide antibiotic. +" C +84029 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a semisynthetic macrolide antibiotic commonly used for a wide variety of mild-to-moderate bacterial infections. +Option B: It is a semisynthetic, tetracycline related bacteriostatic antibiotic. +Option C: It is a bacteriostatic macrolide antibiotic and feed additive used in veterinary medicine. +Option D: It is a semisynthetic macrolide antibiotic. +" D +3485 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC=O)CC=O +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is a penicillin antibiotic. +Option B: It is a narrow spectrum antibiotic. +Option C: It is a macrocyclic antibiotic. +Option D: It exhibits antibiotic function. +" D +470999 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H]([C@H](O[C@@H]1CN)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N)N)N +Question about this molecule: Which kind of antibiotic is this molecule? +Option A: It is an aminoglycoside antibiotic. +Option B: It is a broad spectrum aminoglycoside antibiotic. +Option C: It is an aminoglycoside bacteriocidal antibiotic used to treat a wide variety of infections. +Option D: It is a bactericidal aminoglycoside antibiotic. +" A +9837243 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC[C@@H]1CC(=O)N(C1)[C@@H](CC)C(=O)N +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is a dicarbamate derivative anticonvulsant. +Option B: It possesses anticonvulsant properties. +Option C: It is a benzodiazepine with anticonvulsant properties. +Option D: It is a relatively unique anticonvulsant. +" D +5193 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(C)C1(C(=O)NC(=O)NC1=O)CC=C +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is a relatively unique anticonvulsant. +Option B: It is a benzodiazepine with anticonvulsant properties. +Option C: It is a dicarbamate derivative anticonvulsant. +Option D: It possesses anticonvulsant properties. +" D +4506 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3 +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is a benzodiazepine with anticonvulsant properties. +Option B: It is a benzodiazepine used predominantly as an anticonvulsant. +Option C: It is used as an anticonvulsant in the therapy of partial onset seizures. +Option D: It is a benzodiazepine derivative used as an anticonvulsant and hypnotic. +" D +3331 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(COC(=O)N)COC(=O)N +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is a dicarbamate derivative anticonvulsant. +Option B: It possesses anticonvulsant properties. +Option C: It is a benzodiazepine with anticonvulsant properties. +Option D: It is a relatively unique anticonvulsant. +" A +3016 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3 +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is a benzodiazepine used predominantly as an anticonvulsant. +Option B: It is a benzodiazepine with anticonvulsant properties. +Option C: It is a benzodiazepine derivative used as an anticonvulsant and hypnotic. +Option D: It is used as an anticonvulsant in the therapy of partial onset seizures. +" B +5284583 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H](C(=O)N)N1CCCC1=O +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It possesses anticonvulsant properties. +Option B: It is a relatively unique anticonvulsant. +Option C: It is a dicarbamate derivative anticonvulsant. +Option D: It is a benzodiazepine with anticonvulsant properties. +" B +253881 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Na+].[Br-] +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is an aromatic anticonvulsant used to treat complex, partial and generalized seizures. +Option B: It is used as an antiepileptic medication for dogs and cats. +Option C: It is used as an anticonvulsant in the therapy of partial onset seizures. +Option D: It is a unique anticonvulsant used largely as an adjunctive agent in the treatment of partial seizures. +" B +3446 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(CC1)(CC(=O)O)CN +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is used as an anticonvulsant in the therapy of partial onset seizures. +Option B: It is a unique anticonvulsant used largely as an adjunctive agent in the treatment of partial seizures. +Option C: It is an aromatic anticonvulsant used to treat complex, partial and generalized seizures. +Option D: It is a unique anticonvulsant used as adjunctive therapy in management of epilepsy and for neuropathic pain syndromes. +" D +2802 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3Cl +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is a benzodiazepine used predominantly as an anticonvulsant. +Option B: It is used as an anticonvulsant in the therapy of partial onset seizures. +Option C: It is a benzodiazepine with anticonvulsant properties. +Option D: It is a benzodiazepine derivative used as an anticonvulsant and hypnotic. +" A +121892 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is an aromatic anticonvulsant used to treat complex, partial and generalized seizures. +Option B: It is used as an anticonvulsant in the therapy of partial onset seizures. +Option C: It is a unique anticonvulsant used largely as an adjunctive agent in the treatment of partial seizures. +Option D: It is a unique anticonvulsant used as adjunctive therapy in management of epilepsy and for neuropathic pain syndromes. +" C +3291 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1(CC(=O)NC1=O)C +Question about this molecule: Which kind of anticonvulsant is this molecule? +Option A: It is a unique anticonvulsant used largely as an adjunctive agent in the treatment of partial seizures. +Option B: It is used as an anticonvulsant in the therapy of partial onset seizures. +Option C: It is a succinimide based anticonvulsant commonly used for absence (petit mal) seizures. +Option D: It is a unique anticonvulsant used as adjunctive therapy in management of epilepsy and for neuropathic pain syndromes. +" C +5584 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is used in the therapy of obsessive-compulsive disorder. +Option B: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option C: It is used in the therapy of major (endogenous) as well as reactive (exogenous) depression. +Option D: It is used for relief of symptoms of depression caused by either reactive or psychotic depression. +" C +4543 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC=C1C2=CC=CC=C2CCC3=CC=CC=C31 +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is widely used in the therapy of depression. +Option B: It is used in smoking cessation. +Option C: It is widely used in therapy of depression and smoking cessation. +Option D: It is used for the treatment of moderate to severe depression. +" B +3696 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31 +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is widely used in the therapy of depression. +Option B: It is used for the treatment of moderate to severe depression. +Option C: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option D: It is widely used in therapy of depression and smoking cessation. +" A +2801 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is used for relief of symptoms of depression caused by either reactive or psychotic depression. +Option B: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option C: It is used in the therapy of major (endogenous) as well as reactive (exogenous) depression. +Option D: It is used in the therapy of obsessive-compulsive disorder. +" D +444 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is widely used in the therapy of depression. +Option B: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option C: It is used for the treatment of moderate to severe depression. +Option D: It is widely used in therapy of depression and smoking cessation. +" D +3386 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: Several weeks of therapy may be required before a clinical effect is seen. +Option B: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option C: It has no current clinical applications aside from being a research standard SNRI. +Option D: It is used in the therapy of major (endogenous) as well as reactive (exogenous) depression. +" A +37632 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4 +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option B: It was developed to enhance the antidepressant effects of [alprazolam]. +Option C: It is used in the therapy of major (endogenous) as well as reactive (exogenous) depression. +Option D: It is used in the therapy of obsessive-compulsive disorder. +" B +4205 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4 +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is widely used in the therapy of depression. +Option B: It is used for the treatment of moderate to severe depression. +Option C: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option D: It is widely used in therapy of depression and smoking cessation. +" B +5656 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is a prescription antidepressant. +Option B: It is used as an antidepressant. +Option C: It was developed to enhance the antidepressant effects of [alprazolam]. +Option D: It antagonizes behavioral despair. +" A +4500 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC(C1=CC=CC=C1)OC2=CC=CC=C2OC +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is used in the therapy of major (endogenous) as well as reactive (exogenous) depression. +Option B: It is used in the therapy of obsessive-compulsive disorder. +Option C: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option D: It has no current clinical applications aside from being a research standard SNRI. +" D +146570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCC[C@@]1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is used in the therapy of obsessive-compulsive disorder. +Option B: It is used as an antidepressant to treat depression associated with mood disorders, body dysmorphic disorder, and anxiety, including OCD. +Option C: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option D: It is used in the therapy of major (endogenous) as well as reactive (exogenous) depression. +" B +5530 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(C1N)C2=CC=CC=C2 +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is a prescription antidepressant. +Option B: It antagonizes behavioral despair. +Option C: It was developed to enhance the antidepressant effects of [alprazolam]. +Option D: It is used as an antidepressant. +" D +182137 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN[C@@]1(CCCCC1=O)C2=CC=CC=C2Cl +Question about this molecule: How can the molecule be used as a/an antidepressant +Option A: It is administered as an intranasal spray as therapy of treatment-resistant depression in adults. +Option B: It is used in the therapy of obsessive-compulsive disorder. +Option C: It is used for relief of symptoms of depression caused by either reactive or psychotic depression. +Option D: It is used in the therapy of major (endogenous) as well as reactive (exogenous) depression. +" A +4456 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C +Question about this molecule: Which kind of antidote is this molecule? +Option A: It is an experimental antidote for cyanide poisoning. +Option B: It is an antidote to cyanide poisoning. +Option C: It is an antidote to opioid poisoning. +Option D: It is an antidote to curare poisoning. +" D +135398747 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[N+]1=CC=CC=C1/C=N/O +Question about this molecule: Which kind of antidote is this molecule? +Option A: It is an experimental antidote for cyanide poisoning. +Option B: It is an antidote to organophosphate poisoning and sarin poisoning. +Option C: It is an antidote to cyanide poisoning. +Option D: It is an antidote to benzodiazepine poisoning. +" B +24830990 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(SCC(S1)(C(=O)O)O)(C(=O)O)O +Question about this molecule: Which kind of antidote is this molecule? +Option A: It is an antidote to cyanide poisoning. +Option B: It is an antidote to curare poisoning. +Option C: It is an antidote to opioid poisoning. +Option D: It is an experimental antidote for cyanide poisoning. +" D +2724354 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [C@@H]([C@@H](C(=O)O)S)(C(=O)O)S +Question about this molecule: Which kind of antidote is this molecule? +Option A: It is an antidote to curare poisoning. +Option B: It is an antedote to lead poisoning. +Option C: It is an antidote to opioid poisoning. +Option D: It is an antidote to cyanide poisoning. +" B +23668193 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: N(=O)[O-].[Na+] +Question about this molecule: Which kind of antidote is this molecule? +Option A: It is an antidote to opioid poisoning. +Option B: It is an experimental antidote for cyanide poisoning. +Option C: It is an antidote to cyanide poisoning. +Option D: It is an antidote to curare poisoning. +" C +5707 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C)NC2=NCCCS2 +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It is used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats. +Option B: It is used to treat and prevent postoperative nausea and vomiting in adults, either as monotherapy or in combination with another antiemetic agent of a different drug class. +Option C: It is a potent antiemetic and is used in the treatment of intractable hiccups. +Option D: It is used as an antiemetic and in the treatment of intractable hiccup. +" A +10311306 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC[C@]2(CC[C@]3(CCC(=O)N3)CN2)C4=CC=CC=C4 +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It is used in the therapy of nausea and vomiting associated with medications and gastrointestinal, viral and other illnesses. +Option B: It is used to prevent postoperative or cancer chemotherapy related nausea and vomiting. +Option C: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients. +Option D: It is used to prevent cancer chemotherapy related nausea and vomiting. +" D +3658 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It is used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats. +Option B: It is a potent antiemetic and is used in the treatment of intractable hiccups. +Option C: It is used as an antiemetic and in the treatment of intractable hiccup. +Option D: It is effective as an antiemetic, for relief of anxiety and tension, and as a sedative. +" D +2726 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It is used as an antiemetic and in the treatment of intractable hiccup. +Option B: It is a potent antiemetic and is used in the treatment of intractable hiccups. +Option C: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients. +Option D: It is used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats. +" A +5566 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients. +Option B: It is used as an antipsychotic agent and as an antiemetic. +Option C: It is used as an antipsychotic and an antiemetic. +Option D: It is used as an antiemetic and in the treatment of intractable hiccup. +" C +4917 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It is used to prevent postoperative or cancer chemotherapy related nausea and vomiting. +Option B: It is used in the treatment of vomiting and vertigo. +Option C: It is used to prevent cancer chemotherapy related nausea and vomiting. +Option D: It is widely used in nausea and vomiting. +" D +5568 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It is used as an antiemetic and in the treatment of intractable hiccup. +Option B: It is used as an antipsychotic agent and as an antiemetic. +Option C: It is used as an antipsychotic and an antiemetic. +Option D: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients. +" B +135413536 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NNC(=O)N3)C4=CC=C(C=C4)F +Question about this molecule: Which kind of antiemetic is this molecule? +Option A: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients. +Option B: It is used in the therapy of nausea and vomiting associated with medications and gastrointestinal, viral and other illnesses. +Option C: It is used to prevent cancer chemotherapy related nausea and vomiting. +Option D: It is used to prevent postoperative or cancer chemotherapy related nausea and vomiting. +" D +11338509 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C +Question about this molecule: Which kind of antifungal agrochemical is this molecule? +Option A: It is an anti-peronosporic fungicide. +Option B: It is a fungicide used for various horticultural crops. +Option C: It is a fungicide used for the control of rice blast. +Option D: It is a foliar fungicide. +" A +6328134 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCO[P+](=O)O +Question about this molecule: Which kind of antifungal agrochemical is this molecule? +Option A: It is a fungicide used for various horticultural crops. +Option B: It is an anti-peronosporic fungicide. +Option C: It is a fungicide used for the control of rice blast. +Option D: It is a foliar fungicide. +" A +43234 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)Cl)Cl +Question about this molecule: Which kind of antifungal agrochemical is this molecule? +Option A: It is a foliar fungicide. +Option B: It is a broad spectrum agricultural fungicide. +Option C: It is a broad spectrum fungicide. +Option D: It is a triazole fungicide. +" D +86160 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C +Question about this molecule: Which kind of antifungal agrochemical is this molecule? +Option A: It is a broad-spectrum fungicide. +Option B: It is a broad spectrum fungicide. +Option C: It is a broad spectrum agricultural fungicide. +Option D: It is a foliar fungicide. +" C +34313 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(OC(=C1C(=O)NC2=CC=CC=C2)C)C +Question about this molecule: Which kind of antifungal agrochemical is this molecule? +Option A: It is a novel fungicide. +Option B: It is an obsolete fungicide. +Option C: It is a novel systemic fungicide. +Option D: It is a foliar fungicide. +" B +28780 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCNC(=O)N1C2=CC=CC=C2N=C1NC(=O)OC +Question about this molecule: Which kind of antifungal agrochemical is this molecule? +Option A: It is a broad-spectrum fungicide. +Option B: It is a broad spectrum agricultural fungicide. +Option C: It is a broad spectrum fungicide. +Option D: It is a foliar fungicide. +" D +57957886 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C(=O)NC[C@H](C(C)C)NC(=O)OCC(F)(F)F +Question about this molecule: Which kind of antifungal agrochemical is this molecule? +Option A: It is a novel systemic fungicide. +Option B: It is a novel fungicide. +Option C: It is a foliar fungicide. +Option D: It is an obsolete fungicide. +" A +134692088 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC/C=C/C=C/C=C/CCC1=CC=C(O1)OC(=O)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug. +Option B: It has a role as an antifungal agent and a fungal metabolite. It can be used as an antifungal drug. +Option C: It has a role as an antifungal agent and a marine metabolite. It can be used as an antifungal drug. +Option D: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +" B +46879407 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC/C=C/C(CC)CCC[C@]1(C[C@@H]([C@@H](OO1)CC(=O)O)CC)CC +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as an antifungal agent and a marine metabolite. It can be used as an antifungal drug. +Option B: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug. +Option C: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +Option D: It has a role as an antifungal agent and a fungal metabolite. It can be used as an antifungal drug. +" A +5282071 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H]1/C=C(/C[C@@H](C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC1=O)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC)C)\\C +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +Option B: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug. +Option C: It has a role as an antibacterial agent, an antifungal agent, and a Penicillium metabolite. It can be used as an antifungal drug. +Option D: It has a role as an immunosuppressive agent, an antifungal agent, and a bacterial metabolite. It can be used as an antifungal drug. +" D +11437493 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C/CCCCC(=O)C(C)C(=O)N1CCC[C@@H]1CO +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug. +Option B: It has a role as an antibacterial agent, an antifungal agent, and a Penicillium metabolite. It can be used as an antifungal drug. +Option C: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug. +Option D: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +" B +9860619 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=COC(=C1)C#CC#C/C=C\\CCCCCCCC(=O)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as a fungal metabolite, an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor, an antifungal agent, a Penicillium metabolite, and an apoptosis inducer. It can be used as an antifungal drug. +Option B: It shows potent and broad-spectrum activity in vitro against Candida, Aspergillus, and Trichophyton spp. It has a role as an antifungal agent and a plant metabolite. It can be used as an antifungal drug. +Option C: It has fungistatic properties and has been used in the topical treatment of minor dermatophyte infections. It has a role as an antifungal drug. It can be used as an antifungal drug. +Option D: CJ-01 also shows antifungal activity against various human and phytopathogenic fungi. It has a role as a metabolite, an EC 2.4.1.16 (chitin synthase) inhibitor, and an antifungal agent. It can be used as an antifungal drug. +" B +46173376 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)NCCCCN=C(N)N)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug. +Option B: It has a role as an antibacterial agent, an antifungal agent, and a Penicillium metabolite. It can be used as an antifungal drug. +Option C: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +Option D: It has a role as an antifungal agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, and a plant metabolite. It can be used as an antifungal drug. +" D +64715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)C(=O)O[C@H]1CCC=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: CJ-01 also shows antifungal activity against various human and phytopathogenic fungi. It has a role as a metabolite, an EC 2.4.1.16 (chitin synthase) inhibitor, and an antifungal agent. It can be used as an antifungal drug. +Option B: It has a role as a fungal metabolite, an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor, an antifungal agent, a Penicillium metabolite, and an apoptosis inducer. It can be used as an antifungal drug. +Option C: It shows potent and broad-spectrum activity in vitro against Candida, Aspergillus, and Trichophyton spp. It has a role as an antifungal agent and a plant metabolite. It can be used as an antifungal drug. +Option D: It has fungistatic properties and has been used in the topical treatment of minor dermatophyte infections. It has a role as an antifungal drug. It can be used as an antifungal drug. +" B +54679752 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1O)O)C2=C(C3=C(C=C(C=C3)O)OC2=O)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +Option B: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug. +Option C: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug. +Option D: It has a role as an antibacterial agent, an antifungal agent, and a Penicillium metabolite. It can be used as an antifungal drug. +" A +15958474 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=C)[C@H]1C[C@@H](C(C1)(C)C)C2=C(C3=C(C=C2O)OC4=C(C3=O)C=CC(=C4O)O)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug. +Option B: It has a role as an antibacterial agent, an antifungal agent, and a Penicillium metabolite. It can be used as an antifungal drug. +Option C: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug. +Option D: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +" A +5541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OCC(COC(=O)C)OC(=O)C +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as a fungal metabolite, an EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor, an antifungal agent, a Penicillium metabolite, and an apoptosis inducer. It can be used as an antifungal drug. +Option B: It has fungistatic properties and has been used in the topical treatment of minor dermatophyte infections. It has a role as an antifungal drug. It can be used as an antifungal drug. +Option C: It shows potent and broad-spectrum activity in vitro against Candida, Aspergillus, and Trichophyton spp. It has a role as an antifungal agent and a plant metabolite. It can be used as an antifungal drug. +Option D: CJ-01 also shows antifungal activity against various human and phytopathogenic fungi. It has a role as a metabolite, an EC 2.4.1.16 (chitin synthase) inhibitor, and an antifungal agent. It can be used as an antifungal drug. +" B +214356 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)OP(=O)(O)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as an antibacterial agent, an antifungal agent, and a Penicillium metabolite. It can be used as an antifungal drug. +Option B: It is a member of triazoles, a triazole antifungal drug, and a conazole antifungal drug. It can be used as an antifungal drug. +Option C: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug. +Option D: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug. +" B +121596210 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC/C(=C/CC/C(=C/C[C@]12[C@H](O1)[C@@H](C(=CC2=O)OC)O)/C)/C)C +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as an antifungal agent and a fungal metabolite. It can be used as an antifungal drug. +Option B: It has a role as an Aspergillus metabolite and an antifungal agent. It can be used as an antifungal drug. +Option C: It has a role as an antifungal agent and a marine metabolite. It can be used as an antifungal drug. +Option D: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug. +" B +3316 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCOC1=CC=CC=C1C(=O)N +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has been used as a topical antifungal agent. It can be used as an antifungal drug. +Option B: It has a role as an antifungal agent and a fungal metabolite. It can be used as an antifungal drug. +Option C: It has been shown to exhibit antifungal activity. It can be used as an antifungal drug. +Option D: It has a role as an antifungal agent and a marine metabolite. It can be used as an antifungal drug. +" A +11294 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1=CC=C(C=C1)C(=C2C=CC(=[N+](C)C)C=C2)C3=CC=CC=C3.[Cl-] +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is a potent broad spectrum antifungal agent. +Option B: It has been used as a topical antifungal agent. It can be used as an antifungal drug. +Option C: It has been shown to exhibit antifungal activity. It can be used as an antifungal drug. +Option D: It is used for its anti-fungal properties in aquaculture. +" D +8204 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCN=C(N)N +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has been used as a topical antifungal agent. It can be used as an antifungal drug. +Option B: It is used as a agrochemical fungicide. +Option C: It is used for its anti-fungal properties in aquaculture. +Option D: It is a potent broad spectrum antifungal agent. +" B +47471 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl.[N+](=O)(O)[O-] +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is used for treatment of cutaneous and vaginal infections. +Option B: It is used for the topical treatment of fungal nail infections. +Option C: It is used for the topical treatment of fungal skin infections. +Option D: It is used for treatment of vulvovaginal infections caused by Candida species. +" D +5282433 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCOC1=CC=CC=C1/C(=C\\SC)/N2C=CN=C2 +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is used for the topical treatment of fungal skin infections. +Option B: It is used for the topical treatment of fungal nail infections. +Option C: It is used for the treatment of superficial skin infections. +Option D: It is used for treatment of cutaneous and vaginal infections. +" C +17110 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCN=C(N)N.CC(=O)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: CJ-01 also shows antifungal activity against various human and phytopathogenic fungi. It has a role as a metabolite, an EC 2.4.1.16 (chitin synthase) inhibitor, and an antifungal agent. It can be used as an antifungal drug. +Option B: It shows potent and broad-spectrum activity in vitro against Candida, Aspergillus, and Trichophyton spp. It has a role as an antifungal agent and a plant metabolite. It can be used as an antifungal drug. +Option C: It is used as a fungicide to control black spot and foliar diseases on apples, pears, peaches, nectarines and strawberries. +Option D: It has fungistatic properties and has been used in the topical treatment of minor dermatophyte infections. It has a role as an antifungal drug. It can be used as an antifungal drug. +" C +11499245 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: B1(C2=C(CO1)C=C(C=C2)F)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It has a role as a plant metabolite, an antifungal agent, and a phytotoxin. It can be used as an antifungal drug. +Option B: It is an antifungal drug used for the topical treatment of onychomycosis. +Option C: It is used for the treatment of onychomycosis (fungal infection of the toenails and fingernails). +Option D: It has fungistatic properties and has been used in the topical treatment of minor dermatophyte infections. It has a role as an antifungal drug. It can be used as an antifungal drug. +" C +5282432 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCOC1=CC=CC=C1/C(=C\\SC)/N2C=CN=C2.Cl +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is used for treatment of cutaneous and vaginal infections. +Option B: It is used for the topical treatment of fungal skin infections. +Option C: It is used for the topical treatment of fungal nail infections. +Option D: It is used for the treatment of superficial skin infections. +" D +47472 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is used for treatment of cutaneous and vaginal infections. +Option B: It is used for the topical treatment of fungal nail infections. +Option C: It is used for treatment of vulvovaginal infections caused by Candida species. +Option D: It is used for the topical treatment of fungal skin infections. +" C +5353853 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)Cl)CO/N=C(\\CN2C=CN=C2)/C3=C(C=C(C=C3)Cl)Cl +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is used for the topical treatment of fungal skin infections. +Option B: It is used for treatment of cutaneous and vaginal infections. +Option C: It is used for the topical treatment of fungal nail infections. +Option D: It is used for the treatment of superficial skin infections. +" A +7697 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1OCC(CO)O)Cl +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is used for treatment of vulvovaginal infections caused by Candida species. +Option B: It is used for the topical treatment of fungal skin infections. +Option C: It is used for the topical treatment of fungal nail infections. +Option D: It is used for treatment of cutaneous and vaginal infections. +" D +131379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)C1=C(C=C2[C@@](C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O +Question about this molecule: How can the molecule be used as a/an antifungal drug +Option A: It is used for its anti-fungal properties in aquaculture. +Option B: It has been used as a topical antifungal agent. It can be used as an antifungal drug. +Option C: It has been shown to exhibit antifungal activity. It can be used as an antifungal drug. +Option D: It is a potent broad spectrum antifungal agent. +" D +27400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1 +Question about this molecule: How can the molecule be used as a/an antihistamine +Option A: It is generally used for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option B: It is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. +Option C: It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option D: It is used for treating hay fever, as well as mild cases of Parkinson's disease. +" C +168993 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O +Question about this molecule: How can the molecule be used as a/an antihistamine +Option A: It is used for treating hay fever, as well as mild cases of Parkinson's disease. +Option B: It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option C: It is generally used for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option D: It is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. +" C +5282409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2.C(=C\\C(=O)O)\\C(=O)O +Question about this molecule: How can the molecule be used as a/an antihistamine +Option A: It is used for treating hay fever, as well as mild cases of Parkinson's disease. +Option B: It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option C: It is generally used for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option D: It is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. +" A +2564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 +Question about this molecule: How can the molecule be used as a/an antihistamine +Option A: It is generally used for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option B: It is used for treating hay fever, as well as mild cases of Parkinson's disease. +Option C: It is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. +Option D: It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods. +" B +124087 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4 +Question about this molecule: How can the molecule be used as a/an antihistamine +Option A: It is generally used for the treatment of migraine and the prevention of headache attacks during cluster periods. +Option B: It is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. +Option C: It is used for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions. +Option D: It is generally used as the malate salt for the treatment of migraine and the prevention of headache attacks during cluster periods. +" B +4507 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C +Question about this molecule: How can the molecule be used as a/an antihypertensive agent +Option A: It is used in the treatment of hypertension as a calcium-channel blocker. +Option B: It is used for treatment of hypertension and chronic heart failure as an inhibitor of angiotensin converting enzyme (ACE). +Option C: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist. +Option D: It is used in the management of angina pectoris and hypertension as a calcium-channel blocker and vasodilator. +" A +9351 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=NN=C2NN.Cl +Question about this molecule: How can the molecule be used as a/an antihypertensive agent +Option A: It is used as an antihypertensive agent as a direct-acting vasodilator. +Option B: It is used in the management of angina pectoris and hypertension as a calcium-channel blocker and vasodilator. +Option C: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent. +Option D: It is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease as a selective beta1-receptor blocker. +" A +39186 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC +Question about this molecule: How can the molecule be used as a/an antihypertensive agent +Option A: It is used in the management of angina pectoris and hypertension as a calcium-channel blocker and vasodilator. +Option B: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent. +Option C: It is used for treatment of hypertension and chronic heart failure as an inhibitor of angiotensin converting enzyme (ACE). +Option D: It is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease as a selective beta1-receptor blocker. +" A +62956 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(CC1)[C@@H]2C[C@H](N(C2)C(=O)CP(=O)(CCCCC3=CC=CC=C3)O)C(=O)O +Question about this molecule: How can the molecule be used as a/an antihypertensive agent +Option A: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist. +Option B: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent. +Option C: It is used for the treatment of hypertension as a nonpeptide antagonist of angiotensin II, type 1 (AT1) receptors. +Option D: It is used for treatment of hypertension and chronic heart failure as an inhibitor of angiotensin converting enzyme (ACE). +" D +92974 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1[C@H]([C@@H](C(=O)O)N)O)O)O +Question about this molecule: How can the molecule be used as a/an antihypertensive agent +Option A: It is used for treatment of hypertension and chronic heart failure as an inhibitor of angiotensin converting enzyme (ACE). +Option B: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent. +Option C: It is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease as a selective beta1-receptor blocker. +Option D: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist. +" B +3637 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=NN=C2NN +Question about this molecule: How can the molecule be used as a/an antihypertensive agent +Option A: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent. +Option B: It is used as an antihypertensive agent as a direct-acting vasodilator. +Option C: It is used in the treatment of glaucoma as well as hypertension, arrhythmias, and coronary heart disease as a selective beta1-receptor blocker. +Option D: It is used in the management of angina pectoris and hypertension as a calcium-channel blocker and vasodilator. +" B +4539 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a Quinolone Antimicrobial. +Option B: It is a Sulfonamide Antimicrobial. +Option C: It is a Macrolide Antimicrobial. +Option D: It is a This molecule-class Antimicrobial. +" A +5479 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a Nitroimidazole Antimicrobial. +Option B: It is a Sulfonamide Antimicrobial. +Option C: It is a Macrolide Antimicrobial. +Option D: It is a Quinolone Antimicrobial. +" A +5329 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a Macrolide Antimicrobial. +Option B: It is a This molecule-class Antimicrobial. +Option C: It is a Sulfonamide Antimicrobial. +Option D: It is a Quinolone Antimicrobial. +" C +5379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a Macrolide Antimicrobial. +Option B: It is a Quinolone Antimicrobial. +Option C: It is a This molecule-class Antimicrobial. +Option D: It is a Sulfonamide Antimicrobial. +" B +4173 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CCO)[N+](=O)[O-] +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a Nitroimidazole Antimicrobial. +Option B: It is a Quinolone Antimicrobial. +Option C: It is a Sulfonamide Antimicrobial. +Option D: It is a Macrolide Antimicrobial. +" A +71815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CC(C)O)[N+](=O)[O-] +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. +Option B: It belongs to the family of Hydroxybenzoic Acid Derivatives and has been shown to exhibit anti-microbial function. +Option C: It is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. +Option D: It exhibits anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities. +" A +9571107 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CO/N=C/1\\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a Macrolide Antimicrobial. +Option B: It is a Quinolone Antimicrobial. +Option C: It is a This molecule-class Antimicrobial. +Option D: It is a Sulfonamide Antimicrobial. +" B +54675776 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a Quinolone Antimicrobial. +Option B: It is a This molecule-class Antimicrobial. +Option C: It is a Macrolide Antimicrobial. +Option D: It is a Sulfonamide Antimicrobial. +" B +6423 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([N+](=O)[O-])(Cl)(Cl)Cl +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a chemical compound currently used as a broad-spectrum antimicrobial, fungicide, herbicide, insecticide, and nematicide. +Option B: It is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. +Option C: It exhibits anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities. +Option D: It belongs to the family of Hydroxybenzoic Acid Derivatives and has been shown to exhibit anti-microbial function. +" A +5281612 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a chemical compound currently used as a broad-spectrum antimicrobial, fungicide, herbicide, insecticide, and nematicide. +Option B: It belongs to the family of Hydroxybenzoic Acid Derivatives and has been shown to exhibit anti-microbial function. +Option C: It is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. +Option D: It exhibits anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities. +" D +3599 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It exhibits anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities. +Option B: It is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. +Option C: It is a chemical compound currently used as a broad-spectrum antimicrobial, fungicide, herbicide, insecticide, and nematicide. +Option D: It belongs to the family of Hydroxybenzoic Acid Derivatives and has been shown to exhibit anti-microbial function. +" B +84029 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)O)(C)O +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It is a This molecule-class Antimicrobial. +Option B: It is a Sulfonamide Antimicrobial. +Option C: It is a Macrolide Antimicrobial. +Option D: It is a Quinolone Antimicrobial. +" C +7456 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)C1=CC=C(C=C1)O +Question about this molecule: Which kind of antimicrobial is this molecule? +Option A: It belongs to the family of Hydroxybenzoic Acid Derivatives and has been shown to exhibit anti-microbial function. +Option B: It is a chemical compound currently used as a broad-spectrum antimicrobial, fungicide, herbicide, insecticide, and nematicide. +Option C: It exhibits anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities. +Option D: It is a broad spectrum antimicrobial, anti-leishmanial, phospholipid drug that was originally developed in the 1980s as an anti-cancer agent. +" A +5281421 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C(=O)O[C@H]1C/C(=C/CC/C(=C/[C@@H]2[C@@H]1C(=C)C(=O)O2)/CO)/CO +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a mTOR inhibitor. +Option B: It is a Hsp90 inhibitor. +Option C: It is a proteasome inhibitor. +Option D: It is a protein synthesis inhibitor. +" D +2478 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)OCCCCOS(=O)(=O)C +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It has been used as an antineoplastic agent. +Option B: It is also effective as an antineoplastic agent. +Option C: It is an alkylating antineoplastic agent. +Option D: It is an alkylating agent. +" C +6253 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antimetabolite antineoplastic agent. +Option B: It is also effective as an antineoplastic agent. +Option C: It is a bacterial enzyme that is used as an antineoplastic agent. +Option D: It has been used as an antineoplastic agent. +" A +153970 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)C#N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is also effective as an antineoplastic agent. +Option B: It is a bacterial enzyme that is used as an antineoplastic agent. +Option C: It has been used as an antineoplastic agent. +Option D: It is an antimetabolite antineoplastic agent. +" D +3385 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C(=O)NC(=O)N1)F +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a bacterial enzyme that is used as an antineoplastic agent. +Option B: It is an antimetabolite antineoplastic agent. +Option C: It has been used as an antineoplastic agent. +Option D: It is also effective as an antineoplastic agent. +" B +148123 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. +Option B: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer. +Option C: It is an antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease. +Option D: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +" B +123608 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)C(=O)CN.Cl +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used for the treatment of idiopathic pulmonary fibrosis and cancer. +Option B: It is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. +Option C: It is an antineoplastic agent used for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. +Option D: It is an antineoplastic agent used as monotherapy for advanced ovarian cancer and deleterious germline or somatic BRCA mutation. +" C +23725423 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO.CC(C(=O)O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used as monotherapy for advanced ovarian cancer and deleterious germline or somatic BRCA mutation. +Option B: It is an antineoplastic agent used in combination with bortezomib and dexamethasone for the treatment of multiple myeloma. +Option C: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. +Option D: It is an antineoplastic agent used in combination with trifluridine for treatment of advanced/relapsed unresectable colorectal cancer. +" B +657180 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CC2=CC=C(C=C2)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCC(=O)N6.CC(=O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer. +Option B: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. +Option C: It is an antineoplastic agent used in combination with trifluridine for treatment of advanced/relapsed unresectable colorectal cancer. +Option D: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +" B +135564751 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.O.O.[Na+].[Na+] +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antimetabolite and a radiosensitizing agent. +Option B: It is an antimetabolite and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. +Option C: It is an antimetabolite antineoplastic agent. +Option D: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. +" D +2942 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)N=NC1=C(NC=N1)C(=O)N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an alkylating agent. +Option B: It is an alkylating antineoplastic agent. +Option C: It is also effective as an antineoplastic agent. +Option D: It has been used as an antineoplastic agent. +" A +25051 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)OC2=NC1=N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antimetabolite antineoplastic agent. +Option B: It has been used as an antineoplastic agent. +Option C: It is an antimetabolite. +Option D: It is also effective as an antineoplastic agent. +" C +44558863 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [H+].C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F.[Cl-] +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antimetabolite. +Option B: It has been used as an antineoplastic agent. +Option C: It is also effective as an antineoplastic agent. +Option D: It is an antimetabolite antineoplastic agent. +" A +11685945 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=C(C(=C2O)C1)NCC=C)O)/C)OC)OC(=O)N)\\C)C)O)OC.Cl +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a Hsp90 inhibitor. +Option B: It is a mTOR inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a proteasome inhibitor. +" A +39214 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is also effective as an antineoplastic agent. +Option B: It is an alkylating agent. +Option C: It is an alkylating antineoplastic agent. +Option D: It has been used as an antineoplastic agent. +" B +3690 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(P(=O)(OC1)NCCCl)CCCl +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is also effective as an antineoplastic agent. +Option B: It is a nitrogen mustard alkylating agent. +Option C: It is an alkylating agent. +Option D: It is an alkylating antineoplastic agent. +" B +119182 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antimetabolite antineoplastic agent. +Option B: It has been used as an antineoplastic agent. +Option C: It is also effective as an antineoplastic agent. +Option D: It is a bacterial enzyme that is used as an antineoplastic agent. +" A +44519124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a SMO receptor antagonist and a Hedgehog signaling pathway inhibitor. +Option B: It is a purine analogue and antineoplastic agent used in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option C: It is a cytosine analogue and antineoplastic agent used largely in the therapy of acute leukemia. +Option D: It is a NF-kappaB inhibitor and a p53 activator. +" D +5790 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antimetabolite antineoplastic agent. +Option B: It is an antimetabolite and a radiosensitizing agent. +Option C: It has been used as an antineoplastic agent. +Option D: It is also effective as an antineoplastic agent. +" B +25183872 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: B([C@H](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a mTOR inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is a Hsp90 inhibitor. +Option D: It is a proteasome inhibitor. +" D +6918638 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an EC 3.5.1.98 (histone deacetylase) inhibitor. +Option B: It is a histone deacetylase (HDAC) inhibitor. +Option C: It is an oral histone deacetylase inhibitor and antineoplastic agent. +Option D: It is an oral selective BCL-2 inhibitor and antineoplastic agent. +" B +53239799 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C.Cl +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a Hsp90 inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is a proteasome inhibitor. +Option D: It is an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. +" D +57379018 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC.Cl +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a NF-kappaB inhibitor and a p53 activator. +Option B: It is a fibroblast growth factor receptor antagonist and a vascular endothelial growth factor receptor antagonist. +Option C: It is an epidermal growth factor receptor antagonist. +Option D: It is a SMO receptor antagonist and a Hedgehog signaling pathway inhibitor. +" B +134780 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a bacterial enzyme that is used as an antineoplastic agent. +Option B: It is an immunomodulatory antineoplastic agent. +Option C: It is also effective as an antineoplastic agent. +Option D: It has been used as an antineoplastic agent. +" B +135410875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a parenterally administered folate antagonist and antineoplastic agent. +Option B: It is an antineoplastic agent that acts by inhibitor of cellular mitosis. +Option C: It is an oral selective BCL-2 inhibitor and antineoplastic agent. +Option D: It is a parenterally administered folate antagonist and antineoplastic agent used in the treatment of peripheral T cell lymphomas. +" A +5790 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a pyrimidine analogue used as an antineoplastic agent. +Option B: It is a bacterial enzyme that is used as an antineoplastic agent. +Option C: It has been used as an antineoplastic agent. +Option D: It is also effective as an antineoplastic agent. +" A +6918837 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an oral selective BCL-2 inhibitor and antineoplastic agent. +Option B: It is an antineoplastic agent that acts by inhibitor of cellular mitosis. +Option C: It is an irreversible proteasome inhibitor and antineoplastic agent. +Option D: It is an oral histone deacetylase inhibitor and antineoplastic agent. +" D +169371 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an amino derivative of folic acid, which was once used as an antineoplastic agent. +Option B: It has been used as an antineoplastic agent. +Option C: It is also effective as an antineoplastic agent. +Option D: It is a bacterial enzyme that is used as an antineoplastic agent. +" A +11354606 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@@H]2CC[C@H]3C(=C)C[C@@H](O3)CC[C@]45C[C@@H]6[C@H](O4)[C@H]7[C@@H](O6)[C@@H](O5)[C@@H]8[C@@H](O7)CC[C@@H](O8)CC(=O)C[C@H]9[C@H](C[C@H](C1=C)O2)O[C@@H]([C@@H]9OC)C[C@@H](CN)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is used as an antineoplastic agent and to induce diabetes in experimental animals. +Option B: It is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis. +Option C: It is an inhibitor of microtubule function and is used as an antineoplastic agent. +Option D: It is an antineoplastic agent that acts by inhibitor of cellular mitosis. +" C +20279 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a cytosine analogue and antineoplastic agent used largely in the therapy of acute leukemia. +Option B: It is a purine analogue and antineoplastic agent used primarily in the therapy of hairy cell leukemia. +Option C: It is a purine analogue and antineoplastic agent used in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option D: It is a purine analogue and antineoplastic agent used in the therapy of T cell lymphoblastic leukemia or lymphoma. +" B +5460875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(C(=O)[O-])N)C(=O)N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is also effective as an antineoplastic agent. +Option B: It is an antimetabolite antineoplastic agent. +Option C: It has been used as an antineoplastic agent. +Option D: It is a bacterial enzyme that is used as an antineoplastic agent. +" D +60953 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@H]2[C@@H]([C@@H]([C@H](O2)C)O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is also effective as an antineoplastic agent. +Option B: It is a pyrimidine analogue used as an antineoplastic agent. +Option C: It is a bacterial enzyme that is used as an antineoplastic agent. +Option D: It has been used as an antineoplastic agent. +" B +5311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an irreversible proteasome inhibitor and antineoplastic agent. +Option B: It is an oral selective BCL-2 inhibitor and antineoplastic agent. +Option C: It is an oral histone deacetylase inhibitor and antineoplastic agent. +Option D: It is an antineoplastic agent that acts by inhibitor of cellular mitosis. +" C +126941 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It has been used as an antineoplastic agent. +Option B: It is an antineoplastic and immunosuppressive agent. +Option C: It is also effective as an antineoplastic agent. +Option D: It is a bacterial enzyme that is used as an antineoplastic agent. +" B +3385 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C(=O)NC(=O)N1)F +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a bacterial enzyme that is used as an antineoplastic agent. +Option B: It has been used as an antineoplastic agent. +Option C: It is also effective as an antineoplastic agent. +Option D: It is a pyrimidine analogue used as an antineoplastic agent. +" D +148124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis. +Option B: It is an inhibitor of microtubule function and is used as an antineoplastic agent. +Option C: It is used as an antineoplastic agent and to induce diabetes in experimental animals. +Option D: It is an antineoplastic agent that acts by inhibitor of cellular mitosis. +" A +5352133 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt+2] +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used for the treatment of idiopathic pulmonary fibrosis and cancer. +Option B: It is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. +Option C: It is an antineoplastic agent used as monotherapy for advanced ovarian cancer and deleterious germline or somatic BRCA mutation. +Option D: It is an antineoplastic agent used in combination with trifluridine for treatment of advanced/relapsed unresectable colorectal cancer. +" B +49806720 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +Option B: It is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of advanced non-small cell lung cancer. +Option C: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer. +Option D: It is an antineoplastic agent used in combination with trifluridine for treatment of advanced/relapsed unresectable colorectal cancer. +" B +9854073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. +Option B: It is an antineoplastic agent used as monotherapy for advanced ovarian cancer and deleterious germline or somatic BRCA mutation. +Option C: It is a taxane and antineoplastic agent currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. +Option D: It is an antineoplastic agent used in combination with trifluridine for treatment of advanced/relapsed unresectable colorectal cancer. +" C +60750 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer. +Option B: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. +Option C: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +Option D: It is an antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease. +" C +119182 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a purine analogue and antineoplastic agent used in the therapy of T cell lymphoblastic leukemia or lymphoma. +Option B: It is a purine analogue and antineoplastic agent used primarily in the therapy of hairy cell leukemia. +Option C: It is a cytosine analogue and antineoplastic agent used largely in the therapy of acute leukemia. +Option D: It is a purine analogue and antineoplastic agent used in the therapy of acute lymphoblastic leukemia (ALL) in children. +" D +2578 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCl)NC(=O)N(CCCl)N=O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is also effective as an antineoplastic agent. +Option B: It is an alkylating agent. +Option C: It is a cell-cycle phase nonspecific alkylating antineoplastic agent. +Option D: It is an alkylating antineoplastic agent. +" C +29327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an inhibitor of microtubule function and is used as an antineoplastic agent. +Option B: It is used as an antineoplastic agent and to induce diabetes in experimental animals. +Option C: It is an antineoplastic agent that acts by inhibitor of cellular mitosis. +Option D: It is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis. +" B +4915 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NC(=O)C1=CC=C(C=C1)CNNC +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer. +Option B: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty. +Option C: It is an antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease. +Option D: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +" C +6253 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a cytosine analogue and antineoplastic agent used largely in the therapy of acute leukemia. +Option B: It is a purine analogue and antineoplastic agent used in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option C: It is a purine analogue and antineoplastic agent used primarily in the therapy of hairy cell leukemia. +Option D: It is a purine analogue and antineoplastic agent used in the therapy of T cell lymphoblastic leukemia or lymphoma. +" A +40839 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)N)O)O)CC)OC)C(=O)OC)O +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a vinblastine derivative with antineoplastic activity against cancer. +Option B: It is an oral histone deacetylase inhibitor and antineoplastic agent. +Option C: It is an antineoplastic agent that acts by inhibitor of cellular mitosis. +Option D: It is an oral selective BCL-2 inhibitor and antineoplastic agent. +" A +3011155 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=NC(=NC2=C1N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N +Question about this molecule: Which kind of antineoplastic agent is this molecule? +Option A: It is a purine analogue and antineoplastic agent used primarily in the therapy of hairy cell leukemia. +Option B: It is a purine analogue and antineoplastic agent used in the therapy of T cell lymphoblastic leukemia or lymphoma. +Option C: It is a cytosine analogue and antineoplastic agent used largely in the therapy of acute leukemia. +Option D: It is a purine analogue and antineoplastic agent used in the therapy of acute lymphoblastic leukemia (ALL) in children. +" B +134780 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent and to induce diabetes in experimental animals. +Option B: It is an immunomodulatory antineoplastic agent. +Option C: It is effective as an antineoplastic agent. +Option D: It has been used as an antineoplastic agent. +" B +135410875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option B: It is used as an antineoplastic agent in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. +Option C: It is used as an antineoplastic agent in the therapy of selected forms of advanced non-small cell lung cancer. +Option D: It is used in the treatment of non-small cell lung cancer and malignant mesothelioma. +" D +5790 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)CO)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option B: It is widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis, and rheumatoid arthritis. +Option C: It is used as a continuous hepatic arterial infusion to treat hepatic metastases from colon cancer. +Option D: It is used to treat multiple solid tumors including colon, rectal, breast, gastric, pancreatic, ovarian, bladder, and liver cancer. +" C +6918837 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is approved for use in refractory or relapsed cutaneous T cell lymphoma. +Option B: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option C: It is used as an antineoplastic agent in treatment of refractory multiple myeloma and certain lymphomas. +Option D: It is approved for use in combination with other agents in refractory or relapsed multiple myeloma. +" D +169371 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used in the therapy of refractory chronic lymphocytic leukemia (CLL). +Option B: It is used in the therapy of acute lymphocytic leukemia. +Option C: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option D: It was once used in the treatment of pediatric leukemia. +" D +11354606 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@@H]2CC[C@H]3C(=C)C[C@@H](O3)CC[C@]45C[C@@H]6[C@H](O4)[C@H]7[C@@H](O6)[C@@H](O5)[C@@H]8[C@@H](O7)CC[C@@H](O8)CC(=O)C[C@H]9[C@H](C[C@H](C1=C)O2)O[C@@H]([C@@H]9OC)C[C@@H](CN)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used for refractory, metastatic breast cancer and liposarcoma. +Option B: It is used as an antineoplastic agent in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. +Option C: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option D: It is used to treat metastatic and advanced forms of breast and colon cancer, often in combination with other agents. +" A +20279 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used in the therapy of refractory chronic lymphocytic leukemia (CLL). +Option B: It is used in the therapy of acute lymphocytic leukemia. +Option C: It is used primarily in the therapy of hairy cell leukemia. +Option D: It was once used in the treatment of pediatric leukemia. +" C +5460875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(C(=O)[O-])N)C(=O)N +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of T cell lymphoblastic leukemia or lymphoma. +Option B: It is used in the therapy of acute lymphocytic leukemia. +Option C: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option D: It is used in the therapy of refractory chronic lymphocytic leukemia (CLL). +" B +60953 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@H]2[C@@H]([C@@H]([C@H](O2)C)O)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used to treat multiple solid tumors including colon, rectal, breast, gastric, pancreatic, ovarian, bladder, and liver cancer. +Option B: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option C: It is used as an antineoplastic agent in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. +Option D: It is used to treat metastatic and advanced forms of breast and colon cancer, often in combination with other agents. +" D +5311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is approved for use in combination with other agents in refractory or relapsed multiple myeloma. +Option B: It is approved for use in refractory or relapsed cutaneous T cell lymphoma. +Option C: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option D: It is used as an antineoplastic agent in treatment of refractory multiple myeloma and certain lymphomas. +" B +126941 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option B: It is widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis, and rheumatoid arthritis. +Option C: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option D: It is used to treat multiple solid tumors including colon, rectal, breast, gastric, pancreatic, ovarian, bladder, and liver cancer. +" B +3385 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C(=O)NC(=O)N1)F +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option B: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option C: It is used to treat multiple solid tumors including colon, rectal, breast, gastric, pancreatic, ovarian, bladder, and liver cancer. +Option D: It is widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis, and rheumatoid arthritis. +" C +148124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of selected forms of advanced non-small cell lung cancer. +Option B: It plays a central role in the therapy of many solid tumors including breast and lung cancer. +Option C: It is used in the treatment of advanced ovarian carcinoma. +Option D: It plays a central role in the therapy of ovarian, breast, and lung cancer. +" B +323 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC(=O)O2 +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option B: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option C: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML). +Option D: It is used clinically as an antineoplastic and for the treatment of lymphedema and venous insufficiency. +" D +5352133 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt+2] +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It plays a central role in the therapy of many solid tumors including breast and lung cancer. +Option B: It plays a central role in the therapy of ovarian, breast, and lung cancer. +Option C: It is used as an antineoplastic agent in the therapy of selected forms of advanced non-small cell lung cancer. +Option D: It is used in the treatment of advanced ovarian carcinoma. +" D +49806720 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option B: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option C: It is used as an antineoplastic agent in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. +Option D: It is used as an antineoplastic agent in the therapy of selected forms of advanced non-small cell lung cancer. +" D +9854073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option B: It is used as an antineoplastic agent in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. +Option C: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML). +Option D: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +" B +60750 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis, and rheumatoid arthritis. +Option B: It is used to treat multiple solid tumors including colon, rectal, breast, gastric, pancreatic, ovarian, bladder, and liver cancer. +Option C: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option D: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +" D +119182 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N=C(N=C2N1[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)F)Cl)N +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option B: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML). +Option C: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option D: It is used as an antineoplastic agent in the therapy of T cell lymphoblastic leukemia or lymphoma. +" A +2578 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCl)NC(=O)N(CCCl)N=O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It has been used as an antineoplastic agent. +Option B: It is a cell-cycle phase nonspecific alkylating antineoplastic agent. +Option C: It is effective as an antineoplastic agent. +Option D: It is an immunomodulatory antineoplastic agent. +" B +29327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option B: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML). +Option C: It is used as an antineoplastic agent and to induce diabetes in experimental animals. +Option D: It is used as an antineoplastic agent largely in the therapy of acute leukemia. +" C +4915 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NC(=O)C1=CC=C(C=C1)CNNC +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis, and rheumatoid arthritis. +Option B: It is used as an antineoplastic agent in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian and bladder cancer. +Option C: It is used clinically as an antineoplastic and for the treatment of lymphedema and venous insufficiency. +Option D: It is used as an antineoplastic agent primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease. +" D +6253 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option B: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option C: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML). +Option D: It is used as an antineoplastic agent largely in the therapy of acute leukemia. +" D +40839 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)N)O)O)CC)OC)C(=O)OC)O +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is effective as an antineoplastic agent. +Option B: It is used as an antineoplastic agent and to induce diabetes in experimental animals. +Option C: It has been used as an antineoplastic agent. +Option D: It has antineoplastic activity against cancer. +" D +3011155 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=NC(=NC2=C1N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N +Question about this molecule: What is the right antineoplastic agent information about this molecule? +Option A: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children. +Option B: It is used as an antineoplastic agent in the therapy of T cell lymphoblastic leukemia or lymphoma. +Option C: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations. +Option D: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML). +" B +785 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1O)O +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in water boilers and heating systems. +Option B: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +Option C: It is used as an antioxidant in rubber and food. +Option D: It is used as an antioxidant in food, e.g. oils and fats. +" C +9321 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: NN +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in water boilers and heating systems. +Option B: It is used as an antioxidant in rubber and food. +Option C: It is used as an antioxidant in food, e.g. oils and fats. +Option D: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +" A +31404 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C(=C1)C(C)(C)C)O)C(C)(C)C +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It reduces reactive oxygen species (ROS) by attenuating the expression of ROS-producing enzymes. +Option B: It is used as an antioxidant in animal feeds and for the preservation of color in the production of chili powder, paprika, and ground chili. +Option C: It is used as an antioxidant food additive (E number E321) and antioxidant additive in cosmetics, pharmaceuticals, jet fuels, rubber, petroleum products, electrical transformer oil, and embalming fluid. +Option D: It is used as an antioxidant for mucolytic therapy and the treatment of [acetaminophen] overdose. +" C +6112 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CSS[C@@H]1CCCCC(=O)O +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in rubber and food. +Option B: It acts as a free-radical scavenger. +Option C: It is a free radical scavenger and neuroprotective agent with antioxidant properties. +Option D: It is used as an antioxidant in margarine. +" B +12035 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)N[C@@H](CS)C(=O)O +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant for mucolytic therapy and the treatment of [acetaminophen] overdose. +Option B: It is used as an antioxidant in animal feeds and for the preservation of color in the production of chili powder, paprika, and ground chili. +Option C: It is used as an antioxidant in food, e.g. oils and fats. +Option D: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +" A +5280961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It reduces reactive oxygen species (ROS) by attenuating the expression of ROS-producing enzymes. +Option B: It is used as an antioxidant in animal feeds and for the preservation of color in the production of chili powder, paprika, and ground chili. +Option C: It is used as an antioxidant in food, e.g. oils and fats. +Option D: It is used as an antioxidant for mucolytic therapy and the treatment of [acetaminophen] overdose. +" A +14985 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=C(CC[C@@](O2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C(=C1O)C)C +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +Option B: It is used as an antioxidant in food, e.g. oils and fats. +Option C: It protects cell membranes from oxidative damage. +Option D: It acts as an antioxidant in response to oxidative stress. +" C +61253 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCOC(=O)C1=CC(=C(C(=C1)O)O)O +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in rubber and food. +Option B: It is used as an antioxidant in food, e.g. oils and fats. +Option C: It is used as an antioxidant in water boilers and heating systems. +Option D: It is used as an antioxidant in margarine. +" D +7618 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CO)N(CCO)CCO +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in food, e.g. oils and fats. +Option B: It is used as an antioxidant in water boilers and heating systems. +Option C: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +Option D: It is used as an antioxidant in rubber and food. +" C +16043 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=C(C=CC(=C1)O)O +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in water boilers and heating systems. +Option B: It is used as an antioxidant in rubber and food. +Option C: It is used as an antioxidant in food, e.g. oils and fats. +Option D: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +" C +5281915 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C(=C(C1=O)OC)OC)C/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CCC=C(C)C +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in rubber and food. +Option B: It is used as an antioxidant in margarine. +Option C: It is used as an antioxidant in water boilers and heating systems. +Option D: It is a powerful antioxidant. +" D +23978 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Cu] +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in animal feeds and for the preservation of color in the production of chili powder, paprika, and ground chili. +Option B: It reduces reactive oxygen species (ROS) by attenuating the expression of ROS-producing enzymes. +Option C: It catalyzes the conversion of superoxide radicals (free radicals or ROS) to hydrogen peroxide, which can subsequently be reduced to water by other antioxidant enzymes. +Option D: It is used as an antioxidant food additive (E number E321) and antioxidant additive in cosmetics, pharmaceuticals, jet fuels, rubber, petroleum products, electrical transformer oil, and embalming fluid. +" C +4021 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NN(C(=O)C1)C2=CC=CC=C2 +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in margarine. +Option B: It is used as an antioxidant in rubber and food. +Option C: It is a free radical scavenger and neuroprotective agent with antioxidant properties. +Option D: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +" C +9962735 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=C(C(=C1O)OC)OC)O)C/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CCC=C(C)C +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in animal feeds and for the preservation of color in the production of chili powder, paprika, and ground chili. +Option B: It is used as an antioxidant for mucolytic therapy and the treatment of [acetaminophen] overdose. +Option C: It prevents the initiation and propagation of lipid peroxidation in biological membranes and human low-density lipoprotein (LDL). +Option D: It reduces reactive oxygen species (ROS) by attenuating the expression of ROS-producing enzymes. +" C +124886 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in food, e.g. oils and fats. +Option B: It is used as an antioxidant in water boilers and heating systems. +Option C: It contains the crucial thiol (-SH) group that makes it an effective antioxidant. +Option D: It is used as an antioxidant in rubber and food. +" C +1175 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C12=C(NC(=O)N1)NC(=O)NC2=O +Question about this molecule: How can the molecule be used as a/an antioxidant +Option A: It is used as an antioxidant in rubber and food. +Option B: It acts as an antioxidant in response to oxidative stress. +Option C: It is used as an antioxidant in food, e.g. oils and fats. +Option D: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats. +" B +11705034 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCN(CC1)C2(CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)C(=O)N.Cl.Cl +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is a second generation antipsychotic. +Option B: It is a Typical Antipsychotic. +Option C: It is a potent neuroleptic with antipsychotic properties. +Option D: It is a first generation antipsychotic. +" D +2726 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness. +Option B: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +Option C: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder. +Option D: It was once the most commonly prescribed antipsychotic agent, but is now rarely used. +" D +5566 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is used as an antipsychotic and an antiemetic. +Option B: It is a phenothiazine used as an antipsychotic agent and as an antiemetic. +Option C: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +Option D: It is an atypical antipsychotic used widely in the treatment of mania and schizophrenia. +" A +60854 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54 +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +Option B: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder. +Option C: It is an atypical antipsychotic used widely in the treatment of mania and schizophrenia. +Option D: It is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness. +" A +4917 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is a phenothiazine antipsychotic used principally in the treatment of nausea, vomiting, and vertigo. +Option B: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +Option C: It is a phenothiazine used as an antipsychotic agent and as an antiemetic. +Option D: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder. +" A +213046 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC[C@H]([C@@H](C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)[C@H]6[C@@H]7CC[C@@H](C7)[C@H]6C5=O +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness. +Option B: It is a second generation (atypical) antipsychotic agent used for treatment of schizophrenia. +Option C: It is a second generation (atypical) antipsychotic agent used in the treatment of schizophrenia and bipolar depression. +Option D: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +" C +115237 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is a second generation (atypical) antipsychotic agent taken sublingually, used in the treatment of schizophrenia and manic or mixed episodes associated with bipolar 1 disorder. +Option B: It alleviates both positive and negative symptoms of schizophrenia, and exhibits antidepressant properties in patients with psychiatric disorders, dysthymia, and major depression. +Option C: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder. +Option D: It is a second generation (atypical) antipsychotic agent available in both oral and long acting parenteral forms, used in the treatment of schizophrenia and schizoaffective disorder. +" D +5568 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder. +Option B: It is a phenothiazine used as an antipsychotic agent and as an antiemetic. +Option C: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +Option D: It is a phenothiazine antipsychotic used principally in the treatment of nausea, vomiting, and vertigo. +" B +9429 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +Option B: It is a potent neuroleptic with antipsychotic properties. +Option C: It is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness. +Option D: It is an atypical antipsychotic used widely in the treatment of mania and schizophrenia. +" B +11154555 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C(=O)NC1CCC(CC1)CCN2CCN(CC2)C3=C(C(=CC=C3)Cl)Cl +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +Option B: It is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness. +Option C: It is an atypical antipsychotic used widely in the treatment of mania and schizophrenia. +Option D: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder. +" D +5073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F +Question about this molecule: Which kind of antipsychotic is this molecule? +Option A: It is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness. +Option B: It is an atypical antipsychotic used widely in the treatment of mania and schizophrenia. +Option C: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder. +Option D: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder. +" B +15684 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)Cl)CO +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is used mainly as an antiseptic and antifungal agent. +Option B: It is available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections. +Option C: It has a broad spectrum for bacterial and virus associated with mouth and throat infections. +Option D: It is found in various OTC products to treat conditions of oral infections and inflammation. +" C +2993 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=[N+](C2=CC=CC=C2C(=C1)N)CCCCCCCCCC[N+]3=C(C=C(C4=CC=CC=C43)N)C +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is found in various OTC products to treat conditions of oral infections and inflammation. +Option B: It is used mainly as an antiseptic and antifungal agent. +Option C: It is available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections. +Option D: It has a broad spectrum for bacterial and virus associated with mouth and throat infections. +" A +441373 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)C2=C3C=C(C(=O)C=C3OC4=C(C(=C(C=C24)Br)[O-])[Hg])Br)C(=O)[O-].O.[Na+].[Na+] +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is commonly used as an antiseptic and disinfectant. +Option B: It is used as a topical antiseptic for minor cuts and scrapes. +Option C: It is used mainly as an antiseptic and antifungal agent. +Option D: It is added as antiseptic in mouthwash solutions. +" B +16684434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[Hg]SC1=CC=CC=C1C(=O)[O-].[Na+] +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is used mainly as an antiseptic and antifungal agent. +Option B: It is commonly used as an antiseptic and disinfectant. +Option C: It is added as antiseptic in mouthwash solutions. +Option D: It is used as a topical antiseptic for minor cuts and scrapes. +" A +5054 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC(=C1)O)O +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is used in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. +Option B: It is used mainly as an antiseptic and antifungal agent. +Option C: It is available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections. +Option D: It has a broad spectrum for bacterial and virus associated with mouth and throat infections. +" A +14759 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=C(C=C(C=C1)C)O +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections. +Option B: It has a broad spectrum for bacterial and virus associated with mouth and throat infections. +Option C: It is found in various OTC products to treat conditions of oral infections and inflammation. +Option D: It is used mainly as an antiseptic and antifungal agent. +" A +4133 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)C1=CC=CC=C1O +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is used mainly as an antiseptic and antifungal agent. +Option B: It is added as antiseptic in mouthwash solutions. +Option C: It is commonly used as an antiseptic and disinfectant. +Option D: It is used as a topical antiseptic for minor cuts and scrapes. +" B +2723 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1Cl)C)O +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is added as antiseptic in mouthwash solutions. +Option B: It is used for skin disinfection and surgical instruments. +Option C: It is used mainly as an antiseptic and antifungal agent. +Option D: It is commonly used as an antiseptic and disinfectant. +" B +996 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)O +Question about this molecule: How can the molecule be used as a/an antiseptic +Option A: It is used as a topical antiseptic for minor cuts and scrapes. +Option B: It is commonly used as an antiseptic and disinfectant. +Option C: It is used mainly as an antiseptic and antifungal agent. +Option D: It is added as antiseptic in mouthwash solutions. +" B +65028 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N)C(=O)OCC +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B. +Option B: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +Option C: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option D: It is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. +" A +35370 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-] +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C. +Option B: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option C: It is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. +Option D: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +" C +45375808 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B. +Option B: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C. +Option C: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option D: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +" C +12620 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCO +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. +Option B: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +Option C: It inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby preventing viral entry into cells and subsequent viral replication. +Option D: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +" C +60613 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)C[C@@H](CO)OCP(=O)(O)O +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. +Option B: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option C: It suppresses CMV replication through selective inhibition of viral DNA synthesis. +Option D: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +" C +135398740 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1COC(CO)CO)N=C(NC2=O)N +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a Nucleoside Analog Antiviral. +Option B: It is a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor and Nucleoside Analog Antiviral. +Option C: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option D: It has antiviral and immunosuppressant properties. +" B +5905 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)I)CO)O +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It has antiviral and immunosuppressant properties. +Option B: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option C: It is a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor and Nucleoside Analog Antiviral. +Option D: It is a Nucleoside Analog Antiviral. +" D +135398748 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option B: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B. +Option C: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +Option D: It is a synthetic acyclic guanine derivative with antiviral activity used for the treatment of various herpes simplex virus (HSV) infections. +" D +56640146 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=CC(=CC(=C1OC)C2=CC3=C(C=C2)C=C(C=C3)NS(=O)(=O)C)N4C=CC(=O)NC4=O +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +Option B: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option C: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C. +Option D: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B. +" B +3415 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)(O)P(=O)(O)O +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +Option B: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C. +Option C: It is used intravenously in therapy of serious cytomegalovirus infections, largely in immunocompromised patients. +Option D: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +" C +135398513 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1COCCO)N=C(NC2=O)N +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. +Option B: It is a nucleoside analogue and antiviral inhibitor of hepatitis B virus (HBV) replication which is used alone and in combination with other agents in the therapy of the hepatitis B. +Option C: It is used for therapy of severe novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) infection. +Option D: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B. +" A +44468216 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C2C(=NC=NN2C(=C1)[C@]3([C@@H]([C@@H]([C@H](O3)CO)O)O)C#N)N +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is similar to [remdesivir]. +Option B: It is a Nucleoside Analog Antiviral. +Option C: It is a Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor and Nucleoside Analog Antiviral. +Option D: It has antiviral and immunosuppressant properties. +" A +6253 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O +Question about this molecule: Which kind of antiviral drug is this molecule? +Option A: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C. +Option B: It has antiviral and immunosuppressant properties. +Option C: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C. +Option D: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C. +" B +54675783 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)[C@H]1[C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 30 January 2004. +Option B: It was granted FDA approval on 30 December 1977. +Option C: It was granted FDA approval on 30 June 1971. +Option D: It was granted FDA approval on 1 September 1977. +" C +10836 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](CC1=CC=CC=C1)NC +Question about this molecule: What is the right approval information about this molecule? +Option A: The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 mg of reserpine. +Option B: The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing it in a concentration greater than 25 mg/ml. +Option C: The FDA withdrew its approval for the use of drug products containing nitrofurazone, except for topical drug products formulated for dermatologic application. +Option D: The FDA withdrew its approval for the use of all parenteral drug products containing methamphetamine hydrochloride, a metamfetamine salt. +" D +134780 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N +Question about this molecule: What is the right approval information about this molecule? +Option A: FDA approved on February 8, 2013. +Option B: FDA approved on August 15, 2008. +Option C: FDA approved on July 20, 2018. +Option D: FDA approved on August 30, 2012. +" A +441300 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg). +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children. +" B +119570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN[C@H]1CCC2=C(C1)SC(=N2)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1996. +Option B: It was first approved by the FDA in 1991. +Option C: It was first approved by the FDA in 1997. +Option D: It was initially approved by the FDA in 1991. +" C +6604200 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-] +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 February 1994. +Option B: It was granted FDA approval on 14 April 1995. +Option C: It was granted FDA approval on 24 April 2003. +Option D: It was granted FDA approval on 6 February 1953. +" D +2719 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA Approval on 31 October 1949. +Option B: It was granted FDA approval on 25 March 1974. +Option C: It was granted FDA Approval on 8 March 1954. +Option D: It was granted FDA Approval on 19 December 1973. +" A +54726191 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O +Question about this molecule: What is the right approval information about this molecule? +Option A: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout. +Option B: It was approved by the European Medicines Agency (EMA) in 2009 as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment. +Option C: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option D: A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment. +" C +1123 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CS(=O)(=O)O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially granted FDA approval in 1982. +Option B: It was initially granted FDA approval in 1981. +Option C: The supplements containing taurine were FDA approved by 1984. +Option D: It was granted Breakthrough Therapy status by the FDA. +" C +439213 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H]1[C@H]([C@@H]([C@H](C(O1)O)N)O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: Not approved as a prescription product by the FDA. +Option B: It was approved by the FDA in January 2012. +Option C: It was initially approved by the FDA in 1996. +Option D: It was approved in January 2016 by the FDA. +" A +1549008 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 30 December 1992. +Option B: It was granted FDA approval on 30 June 1971. +Option C: It was granted FDA approval on 30 September 1997. +Option D: It was granted FDA approval on 30 January 2004. +" A +135410875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved by the FDA in February 2011. +Option B: It was initially approved by the FDA in April 2016. +Option C: It was first approved by the FDA in February 4, 2004. +Option D: It was initially approved by the FDA in October 2015. +" C +9837243 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC[C@@H]1CC(=O)N(C1)[C@@H](CC)C(=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It obtained its FDA approval on August 17, 2011. +Option B: It first received FDA approval on April 27, 2012. +Option C: It received FDA approval on February 19, 2016. +Option D: It was granted FDA approval on January 25, 2010. +" C +2554 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC3=CC=CC=C3N2C(=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1966. +Option B: It was initially approved by the FDA in 1992. +Option C: It was initially approved by the FDA in 1996. +Option D: It was initially approved by the FDA in 1965. +" D +6918837 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of external genital warts and perianal warts. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. +Option D: It was previously approved by the U.S. Food and Drug Administration (FDA) under the brand name Farydak for the treatment of a certain type of cancer. +" D +4828 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(COC1=CC=CC2=C1C=CN2)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 3 September 1982. +Option B: It was granted FDA approval on 3 December 1957. +Option C: It was granted FDA approval on 7 December 1953. +Option D: It was granted FDA approval on 14 September 1963. +" A +5281004 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 April 1995. +Option B: It was granted FDA approval on 14 February 1994. +Option C: It was granted FDA approval on 14 September 1995. +Option D: It was granted FDA approval on 14 September 1963. +" B +5104 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1[As](=O)(O)O)[N+](=O)[O-])O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved in an oral formulation for systemic use by the FDA in 1981. +Option B: It has been approved by FDA for use in externally applied drugs and cosmetics. +Option C: It is a FDA approved additive for chicken, turkey and swine feeds. +Option D: It was first approved for use in the U.S. by the Food and Drug Administration in 1965. +" C +2733526 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC/C(=C(\\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 1 September 1977. +Option B: It was granted FDA approval on 30 June 1971. +Option C: It was granted FDA approval on 30 January 2004. +Option D: It was granted FDA approval on 30 December 1977. +" D +25154714 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C(N5)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1992. +Option B: It was initially approved by the FDA in 1999. +Option C: It was FDA approved in 1978. +Option D: It was FDA-approved in July 2015. +" D +9294 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]([C@@H](C1=CC=CC=C1)O)NC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted a type 7 FDA Approval on 29 April 2016. +Option B: It was granted FDA Approval on 19 December 1973. +Option C: It was granted FDA Approval on 8 March 1954. +Option D: It was granted FDA Approval on 31 October 1949. +" A +92786 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It is the first drug to have ever been approved by the US FDA specifically for the treatment of postpartum depression (PPD) in adult females. +Option B: It has recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. +Option C: It was granted a new FDA approval in July 2019 for the treatment of oral ulcers associated with Behcet's disease. +Option D: It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. +" A +5481173 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C(=O)O)O/N=C(/C1=CSC(=N1)N)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC=CC=C4)C(=O)[O-] +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on May 2020. +Option B: It was approved by the FDA on October 30, 2020. +Option C: It was approved by the FDA on December 29, 1964. +Option D: Ceftazidime was approved by the FDA on July 19, 1985. +" D +447715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H]1[C@@H]2C[C@@H](CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3[C@@H]1O)CC[C@@H]4[C@H](C)CCC(=O)O)C)C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially granted FDA approval in 1982. +Option B: It is currently being considered for FDA approval. +Option C: It was granted FDA approval on 30 June 1971. +Option D: It was initially granted FDA approval in 1981. +" B +5343 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=NC(=N1)C)NS(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 7 December 1953. +Option B: It was granted FDA approval on 3 December 1957. +Option C: It was granted FDA approval before 3 December 1957. +Option D: It is unclear whether this drug has been officially approved for use anywhere. +" D +46216142 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+] +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with: +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA). +Option D: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +" C +5358 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 3 September 1982. +Option B: It was granted FDA approval on 28 December 1992. +Option C: It was granted FDA approval on 3 December 1957. +Option D: It was granted FDA approval on 7 December 1953. +" B +3965 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved in an oral formulation for systemic use by the FDA in 1981. +Option B: It was first approved for use in the U.S. market in 1992, but was withdrawn shortly after. +Option C: A transdermal preparation was approved for use in Japan in January 2006. +Option D: It was first approved for use in the U.S. by the Food and Drug Administration in 1965. +" C +6451164 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA). +Option C: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with: +" D +5732 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1991. +Option B: It was initially approved by the FDA in 1999. +Option C: It was first approved by the FDA in 1991. +Option D: It was initially approved by the FDA in 1992. +" D +6398764 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C.C(=C/C(=O)O)\\C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic hepatitis C virus infection (HCV) in adults and children 3 years of age and older who meet specific requirements, as determined by a health care provider. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who meet specific requirements, as determined by a health care provider. +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg) and who have taken HIV medicines in the past. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg). +" D +2366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC1=CC=CC=N1 +Question about this molecule: What is the right approval information about this molecule? +Option A: It is not approved for systemic use due to significant toxicity and lack of appropriate formulation. +Option B: It was remarketed under restricted conditions of use after a supplemental new drug application was approved by the FDA in June 2002. +Option C: It was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. +Option D: It was first approved for use in the U.S. market in 1992, but was withdrawn shortly after. +" C +6741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 24 October 1957. +Option B: It was granted FDA approval on 24 April 2003. +Option C: It was granted FDA approval on 14 February 1994. +Option D: It was granted FDA approval on 14 April 1995. +" A +3036505 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)/C(=C(/C2=CC=CC=C2)\\C3=CC=C(C=C3)OCCO)/CCCl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on July 31, 2009. +Option B: It was FDA approved on August 22, 2008. +Option C: It was FDA approved on February 26, 2013. +Option D: It was FDA approved on July 24, 2012. +" C +54675769 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC2=C1OC(=O)C(=C2O)NC(=O)C3=CC(=C(C=C3)O)CC=C(C)C)O[C@H]4[C@@H]([C@@H]([C@H](C(O4)(C)C)OC)OC(=O)N)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. +Option B: It is part of the FDA drug products withdrawn or removed from the market for reasons of safety or effectiveness. +Option C: In 2009, the FDA determined this molecule sodium was withdrawn from sale for reasons of safety or effectiveness. +Option D: It was remarketed under restricted conditions of use after a supplemental new drug application was approved by the FDA in June 2002. +" C +3869 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 1 May 1984. +Option B: It was granted FDA approval on 30 January 2004. +Option C: It was granted FDA approval on 1 August 1984. +Option D: It was granted FDA approval on 1 September 1977. +" C +3410 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CC1=CC=C(C=C1)OC)NCC(C2=CC(=C(C=C2)O)NC=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved in the United States in 1997. +Option B: It was first approved for use in the United States in 1999. +Option C: It was first approved for use in the United States in 2001. +Option D: It was first approved for use in the United States in 2014. +" C +448223 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)C3=CC=CC=C3)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is currently not approved for use in the United States. +Option B: It is not FDA approved or on the market in the United States. +Option C: It is currently not approved in the United States or Canada. +Option D: It is not approved in the United States. +" B +4636 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy. +Option B: It was first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and reduce the risk for acute urinary retention or the need for surgical procedures. +Option C: It is approved by the FDA for the treatment of schizophrenia and bipolar disorder, but frequently prescribed for off-label purposes including insomnia or the treatment of anxiety disorders. +Option D: It is available in over-the-counter intranasal sprays used to relieve nasal and sinus congestion caused by a wide variety of conditions, such as common cold, hay fever, and upper respiratory allergies. +" D +72078 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)COP(=O)(O)O)O)CCC4=CC(=O)C=C[C@]34C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA Approval on 8 March 1954. +Option B: It was granted FDA Approval on 19 December 1973. +Option C: It was granted FDA approval on 25 March 1974. +Option D: It was granted FDA Approval on 31 October 1949. +" B +2118 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was given FDA approval on October 16, 1981. +Option B: It was granted FDA approval on October 31, 1986. +Option C: It was granted FDA approval on 24 April 2003. +Option D: It was granted FDA approval on 24 October 1957. +" A +10472693 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment. +Option B: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option C: It was approved by the European Medicines Agency (EMA) in 2009 as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment. +Option D: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout. +" A +6212 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(Cl)(Cl)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It is part of the FDA drug products withdrawn or removed from the market for reasons of safety or effectiveness. +Option B: It was remarketed under restricted conditions of use after a supplemental new drug application was approved by the FDA in June 2002. +Option C: It was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. +Option D: In 2009, the FDA determined this molecule sodium was withdrawn from sale for reasons of safety or effectiveness. +" A +5362119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 29 December 1989. +Option B: It was granted FDA approval on 29 December 1987. +Option C: It was granted FDA approval on 31 December 1981. +Option D: It was granted FDA approval on 29 July 1948. +" B +66265 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN[C@@H](C)CC1=CC(=CC=C1)C(F)(F)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children. +Option C: The use of it to treat AML has been granted fast-track status by the U.S. Food and Drug Administration. +Option D: It was for some years in the mid-1990s approved by the United States Food and Drug Administration for the purposes of weight loss. +" D +15130 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H](C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was remarketed under restricted conditions of use after a supplemental new drug application was approved by the FDA in June 2002. +Option B: It was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. +Option C: It was withdrawn from use in the European Union due to its high risk of QT interval prolongation. +Option D: It is not approved for systemic use due to significant toxicity and lack of appropriate formulation. +" C +1548943 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: The most recent FDA approval was Qutenza, an 8% patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia. +Option B: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option C: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout. +Option D: A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment. +" A +45375808 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg) and who have taken HIV medicines in the past. +Option B: It is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic hepatitis C virus infection (HCV) in adults and children 3 years of age and older who meet specific requirements, as determined by a health care provider. +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg). +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who meet specific requirements, as determined by a health care provider. +" B +10184653 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 29 July 1948. +Option B: It was granted FDA approval on 29 December 1987. +Option C: It was granted FDA approval on 29 December 1989. +Option D: It is the first FDA-approved oncology product from Boehringer Ingelheim. +" D +60838 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. +Option B: It was approved for the treatment of advanced pancreatic cancer in October, 2015. +Option C: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia. +Option D: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +" B +6324616 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1/C=C/C=C(\\C(=O)NC2=CC(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies. +Option B: It was approved by the FDA in November 16, 2018 after being granted the designation of Qualified Infectious Disease Product which allowed it to have a status a priority review. +Option C: The FDA emergency use authorization for this molecule and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. It was granted FDA approval on 18 April 1955. +Option D: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations. +" B +107970 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 2016. +Option B: It was approved by the FDA in 2008. +Option C: It was initially approved by the FDA in 2010. +Option D: It was first approved by the FDA in 2013. +" C +5743 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 30 October 1958. +Option B: It was granted FDA approval on 30 December 1992. +Option C: It was granted FDA approval on 30 January 2004. +Option D: It was granted FDA approval on 30 October 1989. +" A +3346 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)OP(=S)(OC)OC)SC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option B: It was approved by the U.S. Food and Drug Administration on December 15, 2008. +Option C: It no longer has Food and Drug Administration approval. +Option D: It was approved by U.S. Food and Drug Administration on August 1, 2017. +" C +5447130 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(OC(=C1)[N+](=O)[O-])/C=N/NC(=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout. +Option B: The FDA withdrew its approval for the use of drug products containing nitrofurazone, except for topical drug products formulated for dermatologic application. +Option C: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option D: A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment. +" B +32051 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Zn+2] +Question about this molecule: What is the right approval information about this molecule? +Option A: It is currently not approved for use in the United States. +Option B: Not approved for use in the United States. +Option C: It is currently not approved in the United States or Canada. +Option D: It is not approved in the United States. +" C +5487427 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)C(C4=CC=CS4)(C5=CC=CS5)O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 30 January 2004. +Option B: It was granted FDA approval on 1 September 1977. +Option C: It was granted FDA approval on 30 December 1977. +Option D: It was granted FDA approval on 30 June 1971. +" A +5284596 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)O)O4)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 13 April 1971. +Option B: It was granted FDA approval on 20 March 1968. +Option C: It was granted FDA approval on 24 April 2003. +Option D: It was granted FDA approval on 20 April 2004. +" A +2333 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br +Question about this molecule: What is the right approval information about this molecule? +Option A: Not approved for use in the United States. +Option B: Not approved in Canada. +Option C: Not approved for use in humans. +Option D: Not approved for sale in the United States or Canada. +" A +12035 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)N[C@@H](CS)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 February 1994. +Option B: It was granted FDA approval on 14 September 1995. +Option C: It was granted FDA approval on 14 September 1963. +Option D: It was granted FDA approval on 14 April 1995. +" C +10607 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of external genital warts and perianal warts. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. +Option C: It was previously approved by the U.S. Food and Drug Administration (FDA) under the brand name Farydak for the treatment of a certain type of cancer. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. +" A +60825 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg). +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children. +" A +4634 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is not approved for systemic use due to significant toxicity and lack of appropriate formulation. +Option B: It has been optimized for high levels of safety and efficacy since initial FDA approval in 1975. +Option C: It was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. +Option D: It was remarketed under restricted conditions of use after a supplemental new drug application was approved by the FDA in June 2002. +" B +59768 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in December, 1997 under the market name Evista® for the management and prevention of osteoporosis in postmenopausal women and reduction in risk for invasive breast cancer in postmenopausal women with osteoporosis or those who are at high risk for invasive breast cancer. +Option B: As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains [LP1196]. +Option C: The FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride that supply 250 milligrams/milliliter of concentrated esmolol per 10-milliliter ampule. +Option D: On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with the BRAF V600E or V600K mutations. +" C +11001318 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C=C1C(=O)O)OC(=N2)C3=CC(=CC(=C3)Cl)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 February 1994. +Option B: It was granted FDA approval on 5 August 1952. +Option C: It was granted an EMA market authorisation on 16 November 2011 and FDA approval on 3 May 2019. +Option D: It was granted FDA approval on 6 February 1953. +" C +60606 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[C@H](C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 7 December 1953. +Option B: It was granted FDA approval on 17 November 1997. +Option C: It was granted FDA approval on 29 July 1948. +Option D: It was granted FDA approval on 29 December 1987. +" B +311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)O)C(CC(=O)O)(C(=O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on May 2020. +Option B: It was approved by the FDA on October 30, 2020. +Option C: It was approved by the FDA on December 29, 1964. +Option D: It was approved by the FDA on December 31, 1987. +" A +60164 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 +Question about this molecule: What is the right approval information about this molecule? +Option A: The FDA emergency use authorization for this molecule and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. It was granted FDA approval on 18 April 1955. +Option B: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations. +Option C: It was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies. +Option D: It was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution. +" D +3652 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO +Question about this molecule: What is the right approval information about this molecule? +Option A: The FDA emergency use authorization for this molecule and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. It was granted FDA approval on 18 April 1955. +Option B: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option C: It was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies. +Option D: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations. +" A +4107 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC=CC=C1OCC(COC(=O)N)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on August 22, 2008. +Option B: It was FDA approved on July 24, 2012. +Option C: It was FDA approved on 15 January 1953. +Option D: It was FDA approved on 16 July 1957. +" D +60961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 30 October 1958. +Option B: It was granted FDA approval on 30 December 1992. +Option C: It was granted FDA approval on 30 January 2004. +Option D: It was granted FDA approval on 30 October 1989. +" D +60877 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg). +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children. +" A +14052 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H](CO)NCCN[C@@H](CC)CO +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 February 1994. +Option B: It was granted FDA approval on 6 February 1953. +Option C: It was granted FDA approval on 6 November 1967. +Option D: It was granted FDA approval on 13 November 1967. +" C +126941 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 3 September 1982. +Option B: It was granted FDA approval on 7 December 1953. +Option C: It was granted FDA approval on 14 September 1963. +Option D: It was granted FDA approval on 3 December 1957. +" B +2327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option B: A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment. +Option C: The FDA has approved another similar levodopa/dopa decarboxylase inhibitor combination in the form of levodopa and carbidopa. +Option D: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout. +" C +2519 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1992. +Option B: It was first approved by the FDA in 1991. +Option C: It was initially approved by the FDA in 1991. +Option D: It was initially approved by the FDA in 1999. +" D +6337614 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@@H]2CN(C(=O)C3=CC=CC(=C23)C1)[C@@H]4CN5CCC4CC5 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the U.S. Food and Drug Administration on December 15, 2008. +Option B: It is the only drug of its class approved for this use by the U.S. Food and Drug Administration. +Option C: It was approved by the Food and Drug Administration in the U.S. in 1964. +Option D: It was first approved for use in the U.S. by the Food and Drug Administration in 1965. +" B +5284632 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC[N+]2(C1)[C@@H]3CC[C@H]2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on January 25, 2010. +Option B: It was granted FDA approval on October 16, 2006. +Option C: It was granted FDA approval on 17 December 2007. +Option D: It was granted FDA approval in 2007. +" D +5509 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is available by prescription only. +Option B: It was approved in the USA in 1974. +Option C: It was initially approved by the FDA in 1996. +Option D: It is approved for use in Japan. +" A +637568 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)/C=C/C(=O)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was the third oral disease-modifying agent for multiple sclerosis approved by the FDA. +Option B: It has recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. +Option C: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +Option D: It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer. +" A +9831415 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC/C=C\\C/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCC(=O)OCC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on February 25, 2015. +Option B: It was approved by the FDA on June 20, 2014. +Option C: It was approved by the FDA on September 27, 2018. +Option D: It was approved by the FDA on July 26, 2012. +" D +54674461 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)NC1=C(N=C(N=C1N)C2=NN(C3=C2C=C(C=N3)F)CC4=CC=CC=C4F)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations. +Option B: It was approved by the FDA in January 2021 for use in certain patients with systolic heart failure. +Option C: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy. +Option D: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +" B +323 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC(=O)O2 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1996. +Option B: It was initially approved by the FDA in 1999. +Option C: It was initially approved by the FDA in 1992. +Option D: It was banned by the FDA in 1954 as a food additive. +" D +3305 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(O)(P(=O)(O)O)P(=O)(O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 30 December 1977. +Option B: It was granted FDA approval on 30 June 1971. +Option C: It was granted FDA approval on 1 September 1977. +Option D: It was granted FDA approval on 30 January 2004. +" C +6279 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@]4(C1=CC(=O)CC4)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 18 June 1959. +Option B: It was granted FDA approval on 7 December 1953. +Option C: It was granted FDA approval on 18 January 1974. +Option D: It was granted FDA approval on 17 November 1997. +" A +4171 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCOC)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1990. +Option B: It was initially approved by the FDA in 1999. +Option C: It was initially approved by the FDA in 1992. +Option D: It was FDA approved in 1978. +" D +5095 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1 +Question about this molecule: What is the right approval information about this molecule? +Option A: It has recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. +Option B: It is the first drug to have ever been approved by the US FDA specifically for the treatment of postpartum depression (PPD) in adult females. +Option C: It was granted a new FDA approval in July 2019 for the treatment of oral ulcers associated with Behcet's disease. +Option D: It was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome in 2005. +" D +4771 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(CC1=CC=CC=C1)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 29 July 1948. +Option B: It was FDA approved for short-term weight management in 1959. +Option C: It was granted FDA approval on 29 December 1989. +Option D: It was granted FDA approval on 29 December 1987. +" B +3121 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(CCC)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on February 25, 2015. +Option B: It was approved by the FDA on December 31, 1987. +Option C: It first received approval from the FDA on February 28, 1978. +Option D: It was approved by the FDA on October 30, 2020. +" C +5754 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 February 1994. +Option B: It was granted FDA approval on 14 April 1995. +Option C: It was granted FDA approval on 6 February 1953. +Option D: It was granted FDA approval on 5 August 1952. +" D +27447 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)SC1)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on December 29, 1964. +Option B: It was approved by the FDA on 4 January 1971. +Option C: It was approved by the FDA on December 31, 1987. +Option D: It was first approved by the FDA on December 31, 1979. +" B +11476460 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4C[C@@H](OC4=O)COP(=O)(O)O)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on September 27, 2018. +Option B: It was approved by the FDA on February 25, 2015. +Option C: It was approved by the FDA on June 20, 2014. +Option D: It was approved by the FDA on July 26, 2012. +" C +5352133 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt+2] +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 29 March 1982. +Option B: It was granted FDA approval on 3 March 1989. +Option C: It was granted FDA approval on 25 March 1974. +Option D: It was granted FDA approval before 29 March 1951. +" B +1727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=CC=C1N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on August 22, 2008. +Option B: It was FDA approved on January 22, 2010. +Option C: It was FDA approved on July 31, 2009. +Option D: It was FDA approved on July 24, 2012. +" B +33613 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 7 December 1953. +Option B: It was granted FDA approval on 18 June 1959. +Option C: It was granted FDA approval on 18 January 1974. +Option D: It was granted FDA approval on 17 November 1997. +" C +5961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)N)[C@@H](C(=O)O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA in October 2004 for the palliative treatment of this condition. +Option B: It was first approved in an oral formulation for systemic use by the FDA in 1981. +Option C: An oral formulation of L-glutamine was approved by the FDA in July 2017. +Option D: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020. +" C +1046 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=C(C=N1)C(=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. +Option B: It is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB). +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children. +" B +3961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 September 1995. +Option B: It was granted FDA approval on 14 February 1994. +Option C: It was granted FDA approval on 14 September 1963. +Option D: It was granted FDA approval on 14 April 1995. +" D +9835049 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)O)C(=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on February 25, 2015. +Option B: It was approved by the FDA on September 27, 2018. +Option C: It was approved by the FDA on July 26, 2012. +Option D: It was approved by the FDA on June 20, 2014. +" A +16850 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved for use in the U.S. market in 1992, but was withdrawn shortly after. +Option B: It has been approved by FDA for use in externally applied drugs and cosmetics. +Option C: It was first approved in an oral formulation for systemic use by the FDA in 1981. +Option D: It was first approved for use in the U.S. by the Food and Drug Administration in 1965. +" B +5253 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 30 October 1989. +Option B: It was first approved as an oral tablet on 30 October 1992. +Option C: It was granted FDA approval on 30 December 1992. +Option D: It was granted FDA approval on 30 October 1958. +" B +5329098 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(N1)/C=C\\2/C3=CC=CC=C3NC2=O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on August 22, 2008. +Option B: It was FDA approved on January 22, 2010. +Option C: It was FDA approved on July 24, 2012. +Option D: It was FDA approved on July 31, 2009. +" A +32798 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CCl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 29 December 1987. +Option B: It was granted FDA approval on 27 December 1985. +Option C: It was granted FDA approval on 29 July 1948. +Option D: It was granted FDA approval on 7 December 1953. +" B +3339 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 31 October 1985. +Option B: It was granted FDA approval on 31 December 1981. +Option C: It was granted FDA approval on 31 December 1993. +Option D: It was granted FDA approval on 28 December 1992. +" C +49806720 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on May 29, 2013. +Option B: It was approved on May 29, 2013. +Option C: It was approved under accelerated approval in 2015. +Option D: It was approved on April 28, 2017. +" C +11273 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CCC(=O)C(=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is not US FDA approved. +Option B: It is not approved by the FDA nor EMA. +Option C: It is not FDA approved as a drug. +Option D: It is not FDA approved or on the market in the United States. +" A +5462501 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)N[C@@H](CCC2=CC=CC=C2)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +Option B: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy. +Option C: It was first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and reduce the risk for acute urinary retention or the need for surgical procedures. +Option D: It is only available as an intravenous injection for the treatment of hypertension when oral therapy is not possible. +" D +3672 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CC1=CC=C(C=C1)C(C)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on December 31, 1987. +Option B: It was first approved by the FDA for sale on November 25, 1997. +Option C: It is approved by the FDA for the long-term treatment of insomnia. +Option D: It is available both by prescription and over-the-counter. +" D +16004 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=NC(=C1)Cl)C(Cl)(Cl)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1999. +Option B: It was initially approved by the FDA in 1990. +Option C: It was approved in the USA in 1974. +Option D: It was initially approved by the FDA in 1991. +" C +6058 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CS)N +Question about this molecule: What is the right approval information about this molecule? +Option A: The FDA emergency use authorization for this molecule and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. It was granted FDA approval on 18 April 1955. +Option B: It was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies. +Option C: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations. +Option D: The first ophthalmic solution for this molecule was granted FDA approval on August 25th 2020. +" D +3007855 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Cl-].[Cl-].[Zn+2] +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 7 December 1953. +Option B: It was granted FDA approval on 3 December 1957. +Option C: It was granted FDA approval before 3 December 1957. +Option D: It was granted FDA approval before 26 June 1986. +" D +6918314 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It first received FDA approval on April 27, 2012. +Option B: It was FDA approved on April 28, 2011. +Option C: It was given FDA approval on January 21, 2011. +Option D: It was granted FDA approval on January 25, 2010. +" C +2764 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C=C32)N4CCNCC4)F)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 7 December 1953. +Option B: It was FDA approved on 15 January 1953. +Option C: It was FDA approved on 16 July 1957. +Option D: The first this molecule-containing product was FDA approved on 22 October 1987. +" D +56959 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C)NC(=O)CN2CCN(CC2)CC(COC3=CC=CC=C3OC)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is available by prescription only. +Option B: It is currently being considered for FDA approval. +Option C: It is a unique, orally available antiangina agent. +Option D: It is approved for use in Japan. +" C +104730 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Co] +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA for the treatment of trichomoniasis and bacterial vaginosis. +Option B: The FDA withdrew its approval for the use of drug products containing cobalt salts. +Option C: The FDA withdrew its approval for the use of drug products containing nitrofurazone, except for topical drug products formulated for dermatologic application. +Option D: It was initially approved by the FDA in 2014 for the treatment of susceptible gram-positive bacteria that cause skin and skin structure infections. +" B +4927 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval before 29 March 1951. +Option B: It was granted FDA approval on 29 March 1982. +Option C: It was granted FDA approval on 25 March 1974. +Option D: It was granted FDA approval on 24 April 2003. +" A +9854073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)OC)C)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option B: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005. +Option C: It was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with: +" A +6917864 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CC[C@](O3)(OO4)C)OC(=O)CCC(=O)O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 11 May 1950. +Option B: It was granted FDA approval on 14 April 1995. +Option C: It was granted FDA approval on 26 May 2020. +Option D: It was granted FDA approval on 24 April 2003. +" C +5565 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CNCCNCCN)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia. +Option B: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020. +Option C: It was approved by the FDA in October 2004 for the palliative treatment of this condition. +Option D: It was initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease. +" D +3058754 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +Option B: It received FDA approval in August 2002 for ""the control of post operative pain and inflammation associated with orthopedic surgery in dogs. +Option C: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy. +Option D: It was approved by the FDA in January 2021 for use in certain patients with systolic heart failure. +" B +644019 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option B: It was granted Orphan Drug designation as well as Fast Track Approval from the FDA for further study in these hard to treat conditions. +Option C: The use of it to treat AML has been granted fast-track status by the U.S. Food and Drug Administration. +Option D: It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005. +" B +54892 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 14 February 1994. +Option B: It was granted FDA approval on 19 February 1948. +Option C: It was granted FDA approval on 6 February 1953. +Option D: It was granted FDA approval on 19 November 1991. +" D +3226 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(OC(F)F)(F)F)(F)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a halogenated inhalational anesthetic initially approved by the FDA in 1972. +Option B: It was approved by the FDA in October 2004 for the palliative treatment of this condition. +Option C: A liposomal inhalation suspension of this drug was approved by the FDA in September 2018. +Option D: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020. +" A +3715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the Food and Drug Administration in the U.S. in 1964. +Option B: It was first approved for use in the U.S. by the Food and Drug Administration in 1965. +Option C: It was approved by U.S. Food and Drug Administration on August 1, 2017. +Option D: It was approved by the U.S. Food and Drug Administration on December 15, 2008. +" B +4409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: It is only available as an intravenous injection for the treatment of hypertension when oral therapy is not possible. +Option B: It was first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and reduce the risk for acute urinary retention or the need for surgical procedures. +Option C: It is a long acting nonsteroidal antiinflammatory drug (NSAID) that is available by prescription only and is used in therapy of chronic arthritis. +Option D: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy. +" C +5281915 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C(=C(C1=O)OC)OC)C/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CC/C=C(\\C)/CCC=C(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It has never been approved by the FDA for clinical use. +Option B: It is not approved by the FDA nor EMA. +Option C: It is not FDA approved or on the market in the United States. +Option D: It is not FDA approved as a drug. +" D +5284583 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H](C(=O)N)N1CCCC1=O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved for use in the United States in 1999. +Option B: It was first approved for use in the United States in 2001. +Option C: It was first approved for use in the United States in 2014. +Option D: It was approved in the United States in 1997. +" A +37768 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1NC(=O)[C@H](CCN)O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)N)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia. +Option B: A liposomal inhalation suspension of this drug was approved by the FDA in September 2018. +Option C: It was approved by the FDA in October 2004 for the palliative treatment of this condition. +Option D: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020. +" B +5329102 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\\2/C3=C(C=CC(=C3)F)NC2=O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was formally approved by the US FDA on January 26, 2006. +Option B: It was approved by the FDA on June 20, 2014. +Option C: It was approved by the FDA on July 26, 2012. +Option D: It was approved by the FDA on September 27, 2018. +" A +60021 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=C(C=C(C=C4)F)F)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It has been approved by FDA for use in externally applied drugs and cosmetics. +Option B: It was first approved in an oral formulation for systemic use by the FDA in 1981. +Option C: It was first approved for use in the U.S. by the Food and Drug Administration in 1965. +Option D: It was first approved for use in the U.S. market in 1992, but was withdrawn shortly after. +" D +3308 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved in the USA in 1974. +Option B: It is approved for use in Japan. +Option C: It is available by prescription only. +Option D: It was initially approved by the FDA in 1996. +" C +5340 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1N)S(=O)(=O)NC2=NC=CS2 +Question about this molecule: What is the right approval information about this molecule? +Option A: The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing it in a concentration greater than 25 mg/ml. +Option B: The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 mg of reserpine. +Option C: The FDA withdrew its approval for the use of all drug products containing sulfathiazole. +Option D: The FDA withdrew its approval for the use of all parenteral drug products containing methamphetamine hydrochloride, a metamfetamine salt. +" C +4926 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31 +Question about this molecule: What is the right approval information about this molecule? +Option A: Not approved for use in the United States. +Option B: It is currently not approved for use in the United States. +Option C: It is not approved in the United States. +Option D: It is currently not approved in the United States or Canada. +" B +1993 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C[N+](C)(C)C)OC(=O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 31 October 1985. +Option B: It was granted FDA approval on 24 April 2003. +Option C: It was granted FDA approval on 24 October 1957. +Option D: It was granted FDA approval on October 31, 1986. +" D +213039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants. +Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg). +Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children. +" C +6251 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on December 31, 1987. +Option B: It was approved by the FDA on December 29, 1964. +Option C: It was approved by the FDA on May 2020. +Option D: It was approved by the FDA on October 30, 2020. +" D +5403 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(C1=CC(=CC(=C1)O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 29 March 1982. +Option B: It was granted FDA approval before 29 March 1951. +Option C: It was granted FDA approval on 25 March 1974. +Option D: It was granted FDA approval on 24 April 2003. +" C +6215 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@@H]4[C@]2(OC(O4)(C)C)C(=O)CO)C[C@@H](C5=CC(=O)C=C[C@@]53C)F)F)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved by the FDA in February 2011. +Option B: It was approved by FDA in May 2016. +Option C: It was initially approved by the FDA in October 2015. +Option D: It was initially approved by the FDA in April 2016. +" B +71815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CC(C)O)[N+](=O)[O-] +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved on March 6, 2015 by the FDA for the treatment of invasive aspergillosis and invasive mucormycosis. +Option B: It was approved by the FDA for the treatment of trichomoniasis and bacterial vaginosis. +Option C: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +Option D: It has been recently approved (late 2012) for the treatment of thrombocytopenia in patients with chronic hepatitis C. +" B +27400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1 +Question about this molecule: What is the right approval information about this molecule? +Option A: It is not FDA approved or on the market in the United States. +Option B: It is not approved by the FDA nor EMA. +Option C: It is not approved by the FDA, Health Canada, or the EMA, but it is approved in individual European countries. +Option D: It was approved by the FDA in April 2014 and has orphan drug status. +" B +4495 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2 +Question about this molecule: What is the right approval information about this molecule? +Option A: It is only available as an intravenous injection for the treatment of hypertension when oral therapy is not possible. +Option B: It was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome in 2005. +Option C: It has recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. +Option D: It is not available in the United States, but is used widely in other countries for the treatment of acute pain. +" D +27125 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1[C@H]([C@H]([C@@H]2O)O)O)CCC4=C3C=CC(=C4)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA Breakthrough Therapy designation in April 2015 and accelerated approval in December 2016. +Option B: It was granted FDA approval for the oral contraceptive Estelle/Nextstellis. +Option C: It was granted FDA approval on 25 March 1974. +Option D: It was granted FDA approval on 29 March 1982. +" B +2972 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C=CN1C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on October 14, 2011. +Option B: It was approved by the FDA on July 26, 2012. +Option C: It was approved by the FDA on February 25, 2015. +Option D: It was approved by the FDA on June 20, 2014. +" A +121396 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)[C@@H](C(=O)O)NC(=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with: +Option B: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005. +Option C: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option D: It was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. +" D +37632 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on May 2020. +Option B: It was approved by the FDA on December 29, 1964. +Option C: It was approved by the FDA on October 30, 2020. +Option D: It has never been approved by the FDA for clinical use. +" D +4205 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted a new FDA approval in July 2019 for the treatment of oral ulcers associated with Behcet's disease. +Option B: It was FDA approved in 2015 for the treatment of basal cell carcinoma. +Option C: It was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. +Option D: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia. +" C +612 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C(=O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations. +Option B: It was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies. +Option C: The FDA emergency use authorization for this molecule and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. It was granted FDA approval on 18 April 1955. +Option D: It was one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. +" D +6047 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA as a combined product called Sinemet on May 2, 1975. +Option B: It was approved by the FDA on May 16, 2018. +Option C: It was approved by the FDA on May 2020. +Option D: It was approved by the FDA on May 2, 2011. +" A +5656 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is not FDA approved or on the market in the United States. +Option B: It is currently not approved in the United States or Canada. +Option C: It is not intended or approved for use in human medicine. +Option D: It is not approved for use in children or adolescents. +" D +2249 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on October 31, 1986. +Option B: It was given FDA approval on October 16, 1981. +Option C: It received FDA approval in September, 1981 under the trade name Tenormin. +Option D: It was granted FDA approval on 24 April 2003. +" C +446987 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H](O1)P(=O)(O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is commercially available as the disodium salt for intravenous administration and as the calcium or trometamol salt for oral administration. +Option B: It is only available as an intravenous injection for the treatment of hypertension when oral therapy is not possible. +Option C: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +Option D: It was granted FDA approval for the oral contraceptive Estelle/Nextstellis. +" A +5284569 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3C(=O)CC4 +Question about this molecule: What is the right approval information about this molecule? +Option A: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020. +Option B: The FDA first approved it for use as part of the cough suppressant syrup Hycodan in March of 1943. +Option C: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy. +Option D: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. +" B +11234049 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4C[C@@H](OC4=O)CO)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations. +Option B: Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®). +Option C: The FDA emergency use authorization for this molecule and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. It was granted FDA approval on 18 April 1955. +Option D: It was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies. +" B +5756 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@H]([C@@H]2O)O)CCC4=C3C=CC(=C4)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the treatment of post-menopausal hot flashes. +Option B: It was approved on March 6, 2015 by the FDA for the treatment of invasive aspergillosis and invasive mucormycosis. +Option C: It has been recently approved (late 2012) for the treatment of thrombocytopenia in patients with chronic hepatitis C. +Option D: It was approved by the FDA for the treatment of trichomoniasis and bacterial vaginosis. +" A +5284607 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C2=CC=CC=C2C1=O)C/C=C(\\C)/CCC[C@H](C)CCC[C@H](C)CCCC(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution. +Option B: The FDA emergency use authorization for this molecule and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. It was granted FDA approval on 18 April 1955. +Option C: Phylloquinone has been synthesized since at least 1939, and was approved by the FDA prior to 1955. +Option D: It was granted FDA approval on November 20, 2020, and is the first FDA-approved treatment for HGPS and other related progeroid laminopathies. +" C +7405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)N[C@@H]1C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: There are currently little to no medicines available that are clinically approved or marketed for employing it as an active ingredient for any particular formal indication. +Option B: It was remarketed under restricted conditions of use after a supplemental new drug application was approved by the FDA in June 2002. +Option C: It was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of evidence supporting its efficacy. +Option D: It is not approved for systemic use due to significant toxicity and lack of appropriate formulation. +" A +11167602 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F +Question about this molecule: What is the right approval information about this molecule? +Option A: FDA approved it on September 27, 2012. +Option B: FDA approved it on December 21, 2012. +Option C: FDA approved on August 30, 2012. +Option D: FDA approved on August 15, 2008. +" A +3007 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CC1=CC=CC=C1)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on October 30, 2020. +Option B: It was approved by the FDA on December 29, 1964. +Option C: The first product of Smith, Kline and French was approved by the FDA on 1976. +Option D: It was approved by the FDA on May 2020. +" C +10127622 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted a new FDA approval in July 2019 for the treatment of oral ulcers associated with Behcet's disease. +Option B: Currently, it is approved solely for the treatment of Neurofibromatosis type 1 (NF-1) in a limited age group. +Option C: It has been recently approved (late 2012) for the treatment of thrombocytopenia in patients with chronic hepatitis C. +Option D: It was granted accelerated approval by the FDA in July 2018 for the treatment of relapsed of refractory acute myeloid leukemia in adults. +" B +5282379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C\\C(=O)O)/C)/C +Question about this molecule: What is the right approval information about this molecule? +Option A: Not approved for use in the United States. +Option B: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option C: It is not available in the United States, but is used widely in other countries for the treatment of acute pain. +Option D: Not approved for sale in the United States or Canada. +" B +54675776 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: The FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing it in a concentration greater than 25 mg/ml. +Option B: The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 mg of reserpine. +Option C: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option D: The FDA withdrew its approval for the use of drug products containing nitrofurazone, except for topical drug products formulated for dermatologic application. +" A +14969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O +Question about this molecule: What is the right approval information about this molecule? +Option A: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca. +Option B: It was initially approved by the FDA in December, 1997 under the market name Evista® for the management and prevention of osteoporosis in postmenopausal women and reduction in risk for invasive breast cancer in postmenopausal women with osteoporosis or those who are at high risk for invasive breast cancer. +Option C: On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with the BRAF V600E or V600K mutations. +Option D: As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains [LP1196]. +" D +3639 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 24 April 2003. +Option B: It was granted FDA approval on 14 February 1994. +Option C: It was granted FDA approval on 12 February 1959. +Option D: It was granted FDA approval on 6 February 1953. +" C +135398513 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1COCCO)N=C(NC2=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 25 March 1974. +Option B: It was granted FDA approval before 29 March 1951. +Option C: It was granted FDA approval on 24 April 2003. +Option D: It was granted FDA approval on 29 March 1982. +" D +6432 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(F)(F)F)(C(F)(F)F)(F)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on June 20, 2014. +Option B: It was approved by the FDA on July 26, 2012. +Option C: It was approved by the FDA on February 25, 2015. +Option D: It was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018. +" D +5755 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 21 June 1955. +Option B: It was granted FDA approval on 24 April 2003. +Option C: It was granted FDA approval on 6 February 1953. +Option D: It was granted FDA approval on 21 February 1955. +" A +5284373 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in 1991. +Option B: It was initially approved by the FDA in 1992. +Option C: It was first approved by the FDA in 1991. +Option D: It was approved for use by the FDA in 1983. +" D +10624 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCC1=CNC2=C1C(=CC=C2)OP(=O)(O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted Breakthrough Therapy status by the FDA. +Option B: It was granted FDA approval on 30 December 1977. +Option C: It was granted FDA approval on 30 January 2004. +Option D: It was granted FDA approval on 30 June 1971. +" A +13109 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially granted FDA approval in 1982. +Option B: It was initially granted FDA approval in 1981. +Option C: It was granted FDA approval on 30 December 1992. +Option D: It was granted FDA approval on 30 September 1997. +" A +51 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)C(=O)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: Not officially approved for this indication. +Option B: Not approved for use in humans. +Option C: Not approved by FDA. +Option D: Not FDA approved. +" A +3000322 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1[C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)[C@H](CO)C4=CC=CC=C4 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on December 29, 1964. +Option B: It was approved by the FDA on December 31, 1987. +Option C: It was first approved by the FDA on December 31, 1979. +Option D: It was approved by the FDA on September 27, 2018. +" C +4946 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(COC1=CC=CC2=CC=CC=C21)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 13 November 1967. +Option B: It was granted FDA approval on 6 February 1953. +Option C: It was granted FDA approval on 6 November 1967. +Option D: It was granted FDA approval on 14 February 1994. +" A +125017 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA in January 2012. +Option B: It was approved by the FDA in September 2014. +Option C: It was approved by the FDA in 2008. +Option D: It was approved by the FDA in December 2014. +" C +132971 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on January 22, 2010. +Option B: It was FDA approved on July 31, 2009. +Option C: It was FDA approved on April 28, 2011. +Option D: It was FDA approved on December 28, 2012. +" C +43815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA in the early 1990s. +Option B: It was initially approved by the FDA in 1999. +Option C: It was initially approved by the FDA in 1990. +Option D: It was initially approved by the FDA in 1996. +" A +54686904 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(=O)NC1=CC(=C2C[C@H]3C[C@H]4[C@@H](C(=O)C(=C([C@]4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005. +Option B: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option C: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005. +Option D: It was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. +" A +10288191 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO +Question about this molecule: What is the right approval information about this molecule? +Option A: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout. +Option B: It was initially approved by the FDA in December, 1997 under the market name Evista® for the management and prevention of osteoporosis in postmenopausal women and reduction in risk for invasive breast cancer in postmenopausal women with osteoporosis or those who are at high risk for invasive breast cancer. +Option C: On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with the BRAF V600E or V600K mutations. +Option D: It was granted accelerated approval by the FDA for the treatment of previously treated, unresectable locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) fusion or another rearrangement as detected by an FDA-approved test. +" C +5388906 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on July 31, 2009. +Option B: It was FDA approved on January 22, 2010. +Option C: It was FDA approved on April 28, 2011. +Option D: It was FDA approved on December 28, 2012. +" D +3779 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(C1=CC(=C(C=C1)O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 6 February 1953. +Option B: It was granted FDA approval on 14 February 1994. +Option C: It was granted FDA approval on 5 August 1952. +Option D: It was granted FDA approval on 19 February 1948. +" D +6435415 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C[C@@H]1C(=O)N/C(=C\\CCCCSC[C@@H](C(=O)O)N)/C(=O)O)C +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA in September 2014. +Option B: It was approved by the FDA in November of 1985. +Option C: It was approved by the FDA in January 2012. +Option D: It was approved by the FDA in December 2014. +" B +3033 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved by the FDA in July 1988. +Option B: It was initially approved by the FDA in 1996. +Option C: It was first approved by the FDA in 1991. +Option D: It was first approved by the FDA in 1997. +" A +9854012 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CSCCNC1=C2C(=NC(=N1)SCCC(F)(F)F)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(C(P(=O)(O)O)(Cl)Cl)O)O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on December 29, 1964. +Option B: It was approved by the FDA on October 30, 2020. +Option C: It was approved by the FDA on May 2020. +Option D: It was approved by the FDA in June 2015 for intravenous application. +" D +47528 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CN=C1)C(=O)NCCO[N+](=O)[O-] +Question about this molecule: What is the right approval information about this molecule? +Option A: Not approved by FDA. +Option B: Not approved in Canada. +Option C: Not FDA approved. +Option D: Not approved for use in humans. +" A +6918585 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CSC[C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)O)O[C@@H]8[C@H](O[C@@H]([C@@H]([C@H]8O)O)O[C@@H]9[C@H](O[C@H](O2)[C@@H]([C@H]9O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)CSCCC(=O)O)O)O)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA on September 27, 2018. +Option B: It was approved by the FDA on June 20, 2014. +Option C: It was approved by the United States FDA on December 15, 2015. +Option D: It was approved by the FDA on July 26, 2012. +" C +3637 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=NN=C2NN +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on 16 July 1957. +Option B: It was FDA approved on July 24, 2012. +Option C: It was FDA approved on 15 January 1953. +Option D: It was FDA approved on August 22, 2008. +" C +71188 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It was first approved by the FDA on December 31, 1979. +Option B: It is approved by the FDA for its veterinary use. +Option C: It was approved by the FDA on December 31, 1987. +Option D: It was approved by the FDA on December 29, 1964. +" B +5328940 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on July 31, 2009. +Option B: It was FDA approved on December 14, 2012. +Option C: It was FDA approved on December 28, 2012. +Option D: It was FDA approved on September 4, 2012. +" D +5284616 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: The FDA approved it for the treatment of patients with lymphangioleiomyomatosis. +Option B: It has been recently approved (late 2012) for the treatment of thrombocytopenia in patients with chronic hepatitis C. +Option C: It was approved on March 6, 2015 by the FDA for the treatment of invasive aspergillosis and invasive mucormycosis. +Option D: It was approved by the FDA for the treatment of trichomoniasis and bacterial vaginosis. +" A +135398508 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option B: It was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. +Option C: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005. +Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with: +" C +3369 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved in the United States in 1997. +Option B: It is approved for use in Japan. +Option C: It was approved in the USA in 1974. +Option D: It was first approved for use in the United States in 2001. +" B +31307 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1C[C@H]([C@@]2(C(=O)CO)O)O)CCC4=CC(=O)C=C[C@@]43C)F)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 3 September 1982. +Option B: It was granted FDA approval before 3 December 1957. +Option C: It was granted FDA approval on 7 December 1953. +Option D: It was granted FDA approval on 3 December 1957. +" D +121892 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N +Question about this molecule: What is the right approval information about this molecule? +Option A: It was FDA approved on December 14, 2012. +Option B: FDA approved it on September 27, 2012. +Option C: FDA approved in June 10, 2011. +Option D: FDA approved it on December 21, 2012. +" C +14982 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA as an existing food sweetener. +Option B: It was approved by the FDA on May 2020. +Option C: It was approved by the FDA on Jan 30, 2012. +Option D: It was approved by the FDA on October 30, 2020. +" A +4485 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval on 28 December 1992. +Option B: It was granted FDA approval on 31 December 1981. +Option C: It was granted FDA approval on 31 December 1993. +Option D: It was granted FDA approval on 31 October 1985. +" B +610479 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It was initially approved by the FDA in April 2016. +Option B: It was initially approved by the FDA in 2016. +Option C: It presents a Status class I by the FDA. +Option D: It was initially approved by the FDA in 1996. +" C +5073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F +Question about this molecule: What is the right approval information about this molecule? +Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with: +Option B: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010. +Option C: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005. +Option D: It was approved by the United States Food and Drug Administration (FDA) in 1993. +" D +5284514 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)/C(=C\\CN2CCCC2)/C3=CC=CC(=N3)/C=C/C(=O)O +Question about this molecule: What is the right approval information about this molecule? +Option A: It is currently available in combination with pseudoephedrine as the FDA-approved product Semprex-D. +Option B: It was approved by the Food and Drug Administration in the U.S. in 1964. +Option C: It was approved by the U.S. Food and Drug Administration on December 15, 2008. +Option D: It was first approved for use in the U.S. by the Food and Drug Administration in 1965. +" A +3033621 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)C2=NC(C(=O)N(C3=C2C=C(C=C3)Cl)CCC#N)O)F +Question about this molecule: What is the right approval information about this molecule? +Option A: Not approved for use in the United States. +Option B: Not approved for use in humans. +Option C: Not approved for sale in the United States or Canada. +Option D: Not approved in Canada. +" C +182137 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN[C@@]1(CCCCC1=O)C2=CC=CC=C2Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: This is the first time that the FDA has approved esketamine for any use. +Option B: It is not approved by the FDA, Health Canada, or the EMA, but it is approved in individual European countries. +Option C: It is not approved by the FDA nor EMA. +Option D: It was approved by the FDA in April 2014 and has orphan drug status. +" A +8612 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCOC(=O)C1=C(C=C(C=C1)N)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: It was approved by the FDA in October 2004 for the palliative treatment of this condition. +Option B: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia. +Option C: Approved by the FDA in September 2022 for ocular surface anesthesia. +Option D: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020. +" C +5284570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3C(=O)CC4 +Question about this molecule: What is the right approval information about this molecule? +Option A: It was granted FDA approval in 2007. +Option B: FDA approved in 2009. +Option C: FDA approved in 1984. +Option D: It was initially approved by the FDA in 2010. +" C +2284 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(CC(=O)O)CN)Cl +Question about this molecule: What is the right approval information about this molecule? +Option A: Approved by the FDA in 1977. +Option B: It was initially approved by the FDA in 2010. +Option C: Approved by the FDA in 2013. +Option D: It was initially approved by the FDA in 2016. +" A +5991 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3C=CC(=C4)O +Question about this molecule: What is the right approval information about this molecule? +Option A: Granted FDA approval on 25 June 1943. +Option B: Granted FDA approval on 3 March 1965. +Option C: It was granted FDA approval on 25 March 1974. +Option D: Granted FDA approval on 4 February 1994. +" A +107782 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COP(=O)(O)O)O)C)O)F)C +Question about this molecule: What is the right approval information about this molecule? +Option A: Granted FDA approval on 4 February 1994. +Option B: Granted FDA approval on 25 June 1943. +Option C: It was granted FDA approval on 25 March 1974. +Option D: Granted FDA approval on 3 March 1965. +" D +153970 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)C#N +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It is under clinical development for the treatment of heart failure with preserved ejection fraction. +Option B: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +Option C: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +Option D: It is currently in clinical development for the treatment of acute myeloid leukemia (AML). +" D +9873 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(C(C(C(F)(F)Br)(F)F)(F)F)(F)F)(C(C(C(F)(F)F)(F)F)(F)F)(F)F +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients. +Option B: It is under clinical development for the treatment of heart failure with preserved ejection fraction. +Option C: It was developed as part of an effort to develop new hormonal contraceptives with reduced adverse effects. +Option D: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +" A +6741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +Option B: The efficacy of it in novel coronavirus pneumonia is being investigated further in clinical trials. +Option C: It is under clinical development for the treatment of heart failure with preserved ejection fraction. +Option D: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +" B +92974 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1[C@H]([C@@H](C(=O)O)N)O)O)O +Question about this molecule: What is the right clinical development information about this molecule? +Option A: Phase 3 clinical trials of Epidiolex have demonstrated clinically significant improvement in Lennox-Gastaut syndrome and Dravet syndrome. +Option B: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +Option C: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. +Option D: It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis. +" C +5280961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. +Option B: It is under clinical development for the treatment of heart failure with preserved ejection fraction. +Option C: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +Option D: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +" C +3121 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(CCC)C(=O)O +Question about this molecule: What is the right clinical development information about this molecule? +Option A: The efficacy of it in novel coronavirus pneumonia is being investigated further in clinical trials. +Option B: It is under clinical development for the treatment of heart failure with preserved ejection fraction. +Option C: It is currently the subject of many clinical trials in a variety of cancer types. +Option D: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +" C +5961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)N)[C@@H](C(=O)O)N +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. +Option B: Clinical trials have revealed that patients on supplementation regimes containing glutamine have improved nitrogen balances, generation of cysteinyl-leukotrienes from polymorphonuclear neutrophil granulocytes and improved lymphocyte recovery and intestinal permeability (in postoperative patients) - in comparison to those who had no glutamine within their dietary regime; all without any side-effects. +Option C: It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis. +Option D: Phase 3 clinical trials of Epidiolex have demonstrated clinically significant improvement in Lennox-Gastaut syndrome and Dravet syndrome. +" B +5565 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CNCCNCCN)N +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It is under clinical development for the treatment of heart failure with preserved ejection fraction. +Option B: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +Option C: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +Option D: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. +" B +644019 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. +Option B: Phase 3 clinical trials of Epidiolex have demonstrated clinically significant improvement in Lennox-Gastaut syndrome and Dravet syndrome. +Option C: It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis. +Option D: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +" B +213039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N +Question about this molecule: What is the right clinical development information about this molecule? +Option A: Clinical trials are underway and are expected to conclude in August 2020. +Option B: The efficacy of it in novel coronavirus pneumonia is being investigated further in clinical trials. +Option C: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +Option D: Its clinical development was terminated in phase II. +" A +66414 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=C(C=C34)OC)O +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +Option B: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011. +Option C: Phase 3 clinical trials of Epidiolex have demonstrated clinically significant improvement in Lennox-Gastaut syndrome and Dravet syndrome. +Option D: It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis. +" D +457928 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)OC(=O)CC(C)(C)C(=O)O)C)C(=O)O +Question about this molecule: What is the right clinical development information about this molecule? +Option A: It is undergoing clinical trials conducted by the pharmaceutical company Panacos. +Option B: The efficacy of it in novel coronavirus pneumonia is being investigated further in clinical trials. +Option C: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +Option D: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes. +" A +439280 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C=C1O)C(=CN2)C[C@@H](C(=O)O)N +Question about this molecule: What is the right clinical development information about this molecule? +Option A: Phase 3 clinical trials of Epidiolex have demonstrated clinically significant improvement in Lennox-Gastaut syndrome and Dravet syndrome. +Option B: Several double-blind placebo-controlled clinical trials have demonstrated its effectiveness in the treatment of depression, though a lack of high quality studies has been noted. +Option C: It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis. +Option D: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women. +" B +449459 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC/C(=C(\\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3 +Question about this molecule: What is the right clinical development information about this molecule? +Option A: Clinical trials are underway and are expected to conclude in August 2020. +Option B: It is being developed by Ascent Therapeutics. +Option C: Its clinical development was terminated in phase II. +Option D: The efficacy of it in novel coronavirus pneumonia is being investigated further in clinical trials. +" B +24781 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=O)NO1 +Question about this molecule: How can the molecule be used for disease control +Option A: It is applied to vegetable, fruit and field crops; livestock; ornamental and forestry plantings; in agricultural premises and domestic settings; in greenhouses, and for control of parasites of fish in designated aquatic environments. +Option B: It is an insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale. +Option C: It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. +Option D: It is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast. +" C +7541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)NC2=NC(=NC(=N2)Cl)Cl)Cl +Question about this molecule: How can the molecule be used for disease control +Option A: It is used for the control of potato and tomato leafspots. +Option B: It is mainly used to control powdery mildew. +Option C: It is most commonly used for the control of chewing and sucking insects, as well as spider mites. +Option D: It is toxic if ingested and is a causative agent of Jamaican Vomiting Sickness. +" A +43226 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)(C3=CN=CN=C3)O)Cl +Question about this molecule: How can the molecule be used for disease control +Option A: It is mainly used to control powdery mildew. +Option B: It is used for the control of potato and tomato leafspots. +Option C: It is toxic if ingested and is a causative agent of Jamaican Vomiting Sickness. +Option D: It is most commonly used for the control of chewing and sucking insects, as well as spider mites. +" A +5853 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(C(C(Cl)(Cl)Cl)O)OC +Question about this molecule: How can the molecule be used for disease control +Option A: It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. +Option B: It is an insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale. +Option C: It is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast. +Option D: It is applied to vegetable, fruit and field crops; livestock; ornamental and forestry plantings; in agricultural premises and domestic settings; in greenhouses, and for control of parasites of fish in designated aquatic environments. +" D +3080 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(CS)S)O +Question about this molecule: How can the molecule be used for disease control +Option A: It is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast. +Option B: It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. +Option C: It is an insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale. +Option D: It has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. +" D +5355863 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C\\C(=O)OC)/OP(=O)(OC)OC +Question about this molecule: How can the molecule be used for disease control +Option A: It is an insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale. +Option B: It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. +Option C: It is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast. +Option D: It is most commonly used for the control of chewing and sucking insects, as well as spider mites. +" D +441445 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C1C[C@H]1C[C@@H](C(=O)O)NC(=O)CC[C@@H](C(=O)O)N +Question about this molecule: How can the molecule be used for disease control +Option A: It is most commonly used for the control of chewing and sucking insects, as well as spider mites. +Option B: It is an insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale. +Option C: It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. +Option D: It is toxic if ingested and is a causative agent of Jamaican Vomiting Sickness. +" D +135398658 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=O)NC(=N3)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is used in moderately high doses for severe forms of epilepsy. +Option B: It causes release of dopamine at higher dosages. +Option C: It impedes the body's ability to create folic acid. +Option D: The recommended dose for dental caries prevention is 6–10 g/day. +" C +5291 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5 +Question about this molecule: What is the right dosage information about this molecule? +Option A: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option B: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +Option C: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +Option D: Doses of GABA 1 to 3 g orally have been used effectively to raise the IQ of mentally retarded persons. +" C +6274 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(NC=N1)C[C@@H](C(=O)O)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +Option B: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +Option C: Infants four to six months old require 33 mg/kg of histidine. +Option D: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +" C +6137 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CSCC[C@@H](C(=O)O)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: Doses of GABA 1 to 3 g orally have been used effectively to raise the IQ of mentally retarded persons. +Option B: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option C: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +Option D: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +" C +5962 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCN)C[C@@H](C(=O)O)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +Option B: At low doses (typically 7 to 10 mg/day), it has been used as a 'venotonic' to promote vein health and small venule blood flow. +Option C: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option D: Children and infants need more- 44 mg/kg per day for an eleven to-twelve-year old, and 97 mg/kg per day for three-to six-month old. +" D +6741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: Low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with long-term immunosuppression. +Option B: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +Option C: It is administered as a single 3-gram oral dose for the treatment of uncomplicated urinary tract infections (UTIs) in females. +Option D: A lower dose of methacholine is required to induce bronchoconstriction in patients with AHR. +" A +5284371 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](C=C4)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +Option B: It is not used in single doses greater than 60mg (and no more than 240 mg in 24 hours) due to a ceiling effect. +Option C: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option D: Doses of GABA 1 to 3 g orally have been used effectively to raise the IQ of mentally retarded persons. +" B +179344 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)O[C@H]1CC2=CC=CC=C2N(C3=CC=CC=C13)C(=O)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +Option B: It is available in 200, 400, 600, or 800mg tablets that are taken once daily, with or without food. +Option C: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +Option D: The 10 mg tablet can be taken without regard to food. +" B +323 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC(=O)O2 +Question about this molecule: What is the right dosage information about this molecule? +Option A: At low doses (typically 7 to 10 mg/day), it has been used as a 'venotonic' to promote vein health and small venule blood flow. +Option B: It is not used in single doses greater than 60mg (and no more than 240 mg in 24 hours) due to a ceiling effect. +Option C: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option D: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +" A +5961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)N)[C@@H](C(=O)O)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is administered as a single 3-gram oral dose for the treatment of uncomplicated urinary tract infections (UTIs) in females. +Option B: A lower dose of methacholine is required to induce bronchoconstriction in patients with AHR. +Option C: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option D: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +" D +4091 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C(=N)N=C(N)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +Option B: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option C: Dose titration and/or use of smaller divided doses may decrease side effects. +Option D: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +" C +445354 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/CO)/C)/C +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is administered as a single 3-gram oral dose for the treatment of uncomplicated urinary tract infections (UTIs) in females. +Option B: Higher doses of vitamin A can be toxic, leading to a constellation of signs and symptoms as well as liver injury, jaundice, enlargement of the liver and spleen, portal hypertension and cirrhosis. +Option C: A lower dose of methacholine is required to induce bronchoconstriction in patients with AHR. +Option D: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +" B +3365 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1F)F)C(CN2C=NC=N2)(CN3C=NC=N3)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: A lower dose of methacholine is required to induce bronchoconstriction in patients with AHR. +Option B: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option C: It is administered as a single 3-gram oral dose for the treatment of uncomplicated urinary tract infections (UTIs) in females. +Option D: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +" B +644019 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is used for long periods at high doses, especially in immunosuppressed patients. +Option B: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option C: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +Option D: It is used in moderately high doses for severe forms of epilepsy. +" D +3000715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(C)C1(C(=O)NC(=S)NC1=O)CC +Question about this molecule: What is the right dosage information about this molecule? +Option A: Small doses have been shown to be anti-analgesic and lower the pain threshold. +Option B: High doses and long term exposure can give rise to various cytotoxic and genotoxic reactions. +Option C: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +Option D: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +" A +177 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC=O +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is used for long periods at high doses, especially in immunosuppressed patients. +Option B: Large doses may cause death from respiratory paralysis. +Option C: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option D: It is used in moderately high doses for severe forms of epilepsy. +" B +6912 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@H](C([C@H](CO)O)O)O)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: The recommended dose for dental caries prevention is 6–10 g/day. +Option B: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option C: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +Option D: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +" A +1993 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C[N+](C)(C)C)OC(=O)C +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +Option B: A lower dose of methacholine is required to induce bronchoconstriction in patients with AHR. +Option C: It is administered as a single 3-gram oral dose for the treatment of uncomplicated urinary tract infections (UTIs) in females. +Option D: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +" B +71815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(N1CC(C)O)[N+](=O)[O-] +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is a single dose orally administered drug. +Option B: It is usually dosed twice daily. +Option C: It causes release of dopamine at higher dosages. +Option D: It is used as a single dose. +" D +5826 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](CC1=CC=CC=C1)N +Question about this molecule: What is the right dosage information about this molecule? +Option A: It causes release of dopamine at higher dosages. +Option B: It is used for long periods at high doses, especially in immunosuppressed patients. +Option C: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option D: It is used in moderately high doses for severe forms of epilepsy. +" A +2249 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(COC1=CC=C(C=C1)CC(=O)N)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: The dose should be as low as possible when given to asthma patients. +Option B: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option C: It is used for long periods at high doses, especially in immunosuppressed patients. +Option D: It is used in moderately high doses for severe forms of epilepsy. +" A +5282452 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1C2=NC3=CC=CC=C3C(=C2/C=C/[C@H](C[C@H](CC(=O)O)O)O)C4=CC=C(C=C4)F +Question about this molecule: What is the right dosage information about this molecule? +Option A: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option B: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +Option C: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +Option D: Doses of GABA 1 to 3 g orally have been used effectively to raise the IQ of mentally retarded persons. +" A +2724385 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1[C@H]([C@H](C[C@@H](O1)O[C@@H]2[C@H](O[C@H](C[C@@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5C[C@H]([C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)O)C)C)C)O)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: It is used for long periods at high doses, especially in immunosuppressed patients. +Option B: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option C: Nausea, vomiting and GIT upset are common, especially in higher doses. +Option D: It is used in moderately high doses for severe forms of epilepsy. +" C +446987 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H](O1)P(=O)(O)O +Question about this molecule: What is the right dosage information about this molecule? +Option A: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option B: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +Option C: It is administered as a single 3-gram oral dose for the treatment of uncomplicated urinary tract infections (UTIs) in females. +Option D: A lower dose of methacholine is required to induce bronchoconstriction in patients with AHR. +" C +23976 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Cr] +Question about this molecule: What is the right dosage information about this molecule? +Option A: High doses and long term exposure can give rise to various cytotoxic and genotoxic reactions. +Option B: It is administered as a single 3-gram oral dose for the treatment of uncomplicated urinary tract infections (UTIs) in females. +Option C: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose. +Option D: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease. +" A +119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)CN +Question about this molecule: What is the right dosage information about this molecule? +Option A: Doses of 10 to 40mg per day were found to result in a 45.8% to 54.6% decrease in LDL cholesterol levels. +Option B: Doses of GABA 1 to 3 g orally have been used effectively to raise the IQ of mentally retarded persons. +Option C: Complete hematologic responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more. +Option D: WHO recommendations amount to 13 mg/kg per 24 h in healthy adults. +" B +2478 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)OCCCCOS(=O)(=O)C +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It has similar efficacy to theophylline but with significantly fewer side effects. +Option B: It has similar efficacy but a superior safety profile compared to tretinoin. +Option C: There is only minimal evidence of efficacy for this condition. +Option D: It provides symptomatic relief but no permanent remission. +" D +65028 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N)C(=O)OCC +Question about this molecule: What is the right efficacy information about this molecule? +Option A: Oseltamivir treatment has limited benefit. +Option B: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA. +Option C: It has similar efficacy to bortezomib in the control of myeloma growth and prevention of bone loss. +Option D: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens. +" A +104838 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It has high efficacy in the treatment of infections of various body systems. +Option B: It has impressive efficacy, reduced risk for extrapyramidal side effects, and reduced susceptibility to drug-drug interactions. +Option C: They have demonstrated high levels of safety, efficacy, and tolerability in clinical trials. +Option D: It has a high rate of efficacy in many types of infection and no severe side effects have been noted. +" A +56206 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It has similar efficacy to theophylline but with significantly fewer side effects. +Option B: It has reduced efficacy compared to other fluoroquinolone antibacterials. +Option C: It has high efficacy in the treatment of infections of various body systems. +Option D: It has a high rate of efficacy in many types of infection and no severe side effects have been noted. +" B +42008 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)CSCC#N)OC)SC2)C(=O)O +Question about this molecule: What is the right efficacy information about this molecule? +Option A: They have demonstrated high levels of safety, efficacy, and tolerability in clinical trials. +Option B: It has a high rate of efficacy in many types of infection and no severe side effects have been noted. +Option C: It has high efficacy in the treatment of infections of various body systems. +Option D: It has impressive efficacy, reduced risk for extrapyramidal side effects, and reduced susceptibility to drug-drug interactions. +" B +60164 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C45CC6CC(C4)CC(C6)C5 +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA. +Option B: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens. +Option C: It has similar efficacy but a superior safety profile compared to tretinoin. +Option D: It demonstrates high efficacy and low toxicity, offering a safer alternative to other drugs used for insomnia. +" C +54454 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It has similar efficacy to bortezomib in the control of myeloma growth and prevention of bone loss. +Option B: It has an efficacy comparable to diazepam; i.e., it inhibits functioning of postsynaptic dopamine receptors. +Option C: It reduces all-cause mortality including fatal and non-fatal CVD and the need for surgical revascularization or angioplasty following a heart attack. +Option D: It has evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack. +" C +6058 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CS)N +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It is a practical and effective option for those affected by ocular cystinosis. +Option B: It has similar efficacy to bortezomib in the control of myeloma growth and prevention of bone loss. +Option C: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA. +Option D: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens. +" A +969516 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It retains its efficacy as a decongestant. +Option B: Its efficacy was first established in controlled trials in the 1960s. +Option C: Poor bioavailability limits its therapeutic efficacy. +Option D: There is only minimal evidence of efficacy for this condition. +" C +54260 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2C[C@H](O[C@H](C2)C)C +Question about this molecule: What is the right efficacy information about this molecule? +Option A: The combination product achieves a sustained virologic response (SVR) between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment. +Option B: It has evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack. +Option C: It is 60-71% effective in treating toenail onychomycosis; complete cure rates three months after stopping treatment were 38-46%. +Option D: It achieves a sustained virologic response (SVR) between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment. +" C +25183872 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: B([C@H](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It has similar efficacy to bortezomib in the control of myeloma growth and prevention of bone loss. +Option B: It has evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack. +Option C: It has an efficacy comparable to diazepam; i.e., it inhibits functioning of postsynaptic dopamine receptors. +Option D: It reduces all-cause mortality including fatal and non-fatal CVD and the need for surgical revascularization or angioplasty following a heart attack. +" A +62156 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CC=C3)C(=O)OC +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens. +Option B: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA. +Option C: It is approximately 10–20 times less potent than carfentanil and is the maximum strength fentanyl analog for use in humans. +Option D: It has an efficacy comparable to diazepam; i.e., it inhibits functioning of postsynaptic dopamine receptors. +" C +5656 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It retains its efficacy as a decongestant. +Option B: Poor bioavailability limits its therapeutic efficacy. +Option C: There is only minimal evidence of efficacy for this condition. +Option D: Its efficacy was first established in controlled trials in the 1960s. +" C +13109 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34 +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It is approximately 10–20 times less potent than carfentanil and is the maximum strength fentanyl analog for use in humans. +Option B: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens. +Option C: It demonstrates high efficacy and low toxicity, offering a safer alternative to other drugs used for insomnia. +Option D: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA. +" B +53232 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It has evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack. +Option B: It has similar efficacy to bortezomib in the control of myeloma growth and prevention of bone loss. +Option C: It has an efficacy comparable to diazepam; i.e., it inhibits functioning of postsynaptic dopamine receptors. +Option D: It reduces all-cause mortality including fatal and non-fatal CVD and the need for surgical revascularization or angioplasty following a heart attack. +" A +5073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It reduces all-cause mortality including fatal and non-fatal CVD and the need for surgical revascularization or angioplasty following a heart attack. +Option B: It has similar efficacy to bortezomib in the control of myeloma growth and prevention of bone loss. +Option C: It has an efficacy comparable to diazepam; i.e., it inhibits functioning of postsynaptic dopamine receptors. +Option D: It has evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack. +" C +31264 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1OC(OC(O1)C)C +Question about this molecule: What is the right efficacy information about this molecule? +Option A: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens. +Option B: It has similar efficacy to bortezomib in the control of myeloma growth and prevention of bone loss. +Option C: Its efficacy for this indication has not been confirmed and its use as an expectorant may possibly be due to a placebo effect. +Option D: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA. +" C +3100 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCOC(C1=CC=CC=C1)C2=CC=CC=C2 +Question about this molecule: What is the right efficacy information about this molecule? +Option A: Its efficacy was first established in controlled trials in the 1960s. +Option B: It retains its efficacy as a decongestant. +Option C: There is only minimal evidence of efficacy for this condition. +Option D: Poor bioavailability limits its therapeutic efficacy. +" B +199 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCN=C(N)N)CN +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used as a versatile experimental tool for studying pain mechanisms and for pharmacotherapy to treat some peripheral painful states. +Option B: It can be used for treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option C: It can be used to study the carcinogenicity and mutagenicity of aromatic amines. +Option D: It can be used for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection, and psychiatric conditions. +" D +98888 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN1CCNCCN +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used as a versatile experimental tool for studying pain mechanisms and for pharmacotherapy to treat some peripheral painful states. +Option B: It can be used to study the carcinogenicity and mutagenicity of aromatic amines. +Option C: It can be used for treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option D: It can be used for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection, and psychiatric conditions. +" C +1548943 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used to study the carcinogenicity and mutagenicity of aromatic amines. +Option B: It can be used for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection, and psychiatric conditions. +Option C: It can be used for treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option D: It can be used as a versatile experimental tool for studying pain mechanisms and for pharmacotherapy to treat some peripheral painful states. +" D +5802 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C(=O)NC(=O)N1)Br +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used as an antineoplastic agent and to induce diabetes in experimental animals. +Option B: It can be used as an experimental drug with no known approved indications. +Option C: It can be used as an experimental anticancer drug that is activated in hypoxic conditions. +Option D: It can be used as an experimental mutagen. +" D +5897 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NC1=CC2=C(C=C1)C3=CC=CC=C3C2 +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used to study the carcinogenicity and mutagenicity of aromatic amines. +Option B: It can be used for treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option C: It can be used as a versatile experimental tool for studying pain mechanisms and for pharmacotherapy to treat some peripheral painful states. +Option D: It can be used for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection, and psychiatric conditions. +" A +6112 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CSS[C@@H]1CCCCC(=O)O +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used to study the cellular uptake of glucose and its potential use in diabetes. +Option B: It can be used as an experimental anticancer drug that is activated in hypoxic conditions. +Option C: It can be used as an experimental drug with no known approved indications. +Option D: It can be used as an antineoplastic agent and to induce diabetes in experimental animals. +" A +3080 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(CS)S)O +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used as an experimental antidote against the arsenic-based poison gas Lewisite. +Option B: It can be used as an experimental anticancer drug that is activated in hypoxic conditions. +Option C: It can be used as an antineoplastic agent and to induce diabetes in experimental animals. +Option D: It can be used as an experimental drug with no known approved indications. +" A +29327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used as an experimental drug with no known approved indications. +Option B: It can be used as a versatile experimental tool for studying pain mechanisms and for pharmacotherapy to treat some peripheral painful states. +Option C: It can be used as an experimental anticancer drug that is activated in hypoxic conditions. +Option D: It can be used as an antineoplastic agent and to induce diabetes in experimental animals. +" D +440667 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H]([C@@H]1C(=O)C(=O)C(=O)O1)O)O +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used as an experimental drug with no known approved indications. +Option B: It can be used as a versatile experimental tool for studying pain mechanisms and for pharmacotherapy to treat some peripheral painful states. +Option C: It can be used as an antineoplastic agent and to induce diabetes in experimental animals. +Option D: It can be used as an experimental anticancer drug that is activated in hypoxic conditions. +" A +51 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)C(=O)C(=O)O +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used to study the cellular uptake of glucose and its potential use in diabetes. +Option B: It can be used to help remove excess ammonia in hemodialysis patients. +Option C: It can be used as an experimental drug with no known approved indications. +Option D: It can be used as an antineoplastic agent and to induce diabetes in experimental animals. +" B +456468 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC[C@H](C(=O)O)N +Question about this molecule: How can the molecule be used for experiment +Option A: It can be used as an antineoplastic agent and to induce diabetes in experimental animals. +Option B: It can be used as an experimental mutagen. +Option C: It can be used as an experimental drug with no known approved indications. +Option D: It can be used experimentally to study protein structure and function. +" D +25429 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)NC1=NC2=CC=CC=C2N1 +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a mixture and a morpholine fungicide. +Option B: It is a furanilide fungicide. +Option C: It is a benzimidazole fungicide. +Option D: It is a thiadiazole antifungal agent. +" C +446845 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It has excellent activity against a wide range of plant pathogenic fungi, especially gray mould diseases caused by Botrytis cinerea. +Option B: It is a foliar applied fungicide for cereals particularly active against Ascomycetes, Deuteromycetes and Oomycetes. +Option C: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts. +Option D: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases. +" D +11527333 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C1=C(C=C(C=C1)Cl)Cl)NC(=O)C(C#N)C(C)(C)C +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is used for the control of rice blast in paddy fields. +Option B: It is a fungicide used for the control of rice blast. +Option C: It is a fungicide particularly for the control of fungal diseases in rice. +Option D: It is used to control rice blast and is not approved for use within the European Union. +" A +11057755 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)F)OC +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide used for the control of rice blast. +Option B: It is used as a fungicide and plant activator. +Option C: It is a fungicide particularly for the control of fungal diseases in rice. +Option D: It is a mixture and a morpholine fungicide. +" D +6100711 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CNC(=S)[S-])NC(=S)[S-].[Zn+2] +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a foliar applied fungicide for cereals particularly active against Ascomycetes, Deuteromycetes and Oomycetes. +Option B: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases. +Option C: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts. +Option D: It is used to control a wide range of fungal diseases, including downy mildew, brown rot, black rot, red fire, leaf spot, and blight in crops such as grapes, tomatoes, potatoes, berries, citrus, rice and tea. +" D +10171321 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C2C(=C1)N=NS2)C(=O)S +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide used for the control of rice blast. +Option B: It is a fungicide particularly for the control of fungal diseases in rice. +Option C: It is used as a fungicide and plant activator. +Option D: It is a fungicide developed in China with high antifungal activity against specific diseases. +" C +11338509 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a mixture and a morpholine fungicide. +Option B: It is a diastereoisomeric mixture and an acylamino acid fungicide. +Option C: It is an anilide fungicide. +Option D: It is a furanilide fungicide. +" B +93362 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)SC1=CC=C(C=C1)OS(=O)(=O)C +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a non-systemic fungicide widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops. +Option B: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. +Option C: It is used for the treatment of a range of fungal diseases in rice. +Option D: It is a fungicide particularly for the control of fungal diseases in rice. +" C +91731 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide used to control grey mould, downy mildew and other fungal pathogens. +Option B: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes. +Option C: It is a fungicide for the control of late blight and downy mildew on potatoes and other crops. +Option D: It is a fungicide for use on potatoes to control late blight and downy mildew. +" A +62097 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCNC(=O)OCC#CI +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide for the control of surface moulds and sapstain fungi on wood. +Option B: It is a fungicide used as a preservative and sapstain control chemical in wood products. +Option C: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes. +Option D: It is a fungicide used to control grey mould, downy mildew and other fungal pathogens. +" B +90590 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CO1)C(=O)NC2=CC=CC=C2 +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a furanilide fungicide. +Option B: It is a mixture and a morpholine fungicide. +Option C: It is an anilide fungicide. +Option D: It is a fungicide used for the control of rice blast. +" A +28780 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCNC(=O)N1C2=CC=CC=C2N=C1NC(=O)OC +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. +Option B: It is a fungicide for the control of late blight and downy mildew on potatoes and other crops. +Option C: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. +Option D: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes. +" A +135424353 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC1=C(N=C(NC1=O)N(C)C)C +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide with a wide spectrum of activity and inhibits the enzymatic activity of pyruvate kinase. +Option B: It is a fungicide for use in cereals for key stem and leaf disease control including strobilurin-resistant septoria. +Option C: It is an aminopyrimidine, a tertiary amino compound, a hydroxypyrimidine and a pyrimidine fungicide. +Option D: It is a foliar applied fungicide for cereals particularly active against Ascomycetes, Deuteromycetes and Oomycetes. +" C +11629002 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(N=C2C(=CC(=CC2=C1OC(=O)C)C(C)(C)C)F)C +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide developed in China with high antifungal activity against specific diseases. +Option B: It is a fungicide particularly for the control of fungal diseases in rice. +Option C: It is a fungicide used for the control of rice blast. +Option D: It is a fungicide developed mainly for the control of rice blast (Magnaporthe grisea). +" D +5364079 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC(=O)NC(=O)/C(=N/OC)/C#N +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. +Option B: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. +Option C: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes. +Option D: It is a fungicide for the control of late blight and downy mildew on potatoes and other crops. +" C +7862 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[Hg]Cl +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. +Option B: It is a non-systemic fungicide widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops. +Option C: It is a fungicide particularly for the control of fungal diseases in rice. +Option D: It is a highly toxic organomercury compound used as a fungicide for treating seeds. +" D +6112114 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\\OC)/C(=O)OC +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. +Option B: It is a fungicide for the control of late blight and downy mildew on potatoes and other crops. +Option C: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes. +Option D: It is a foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. +" A +11434448 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=C(C(=N1)C(F)F)C(=O)NC2=C(C=C(C=C2)F)C3=CC(=C(C=C3)Cl)Cl +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a foliar applied fungicide for cereals particularly active against Ascomycetes, Deuteromycetes and Oomycetes. +Option B: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts. +Option C: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases. +Option D: It is a fungicide for use in cereals for key stem and leaf disease control including strobilurin-resistant septoria. +" D +22772 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(SC#N)SC#N +Question about this molecule: Which kind of fungicide is this molecule? +Option A: It is a fungicide for the control of surface moulds and sapstain fungi on wood. +Option B: It is a fungicide used as a preservative and sapstain control chemical in wood products. +Option C: It is a fungicide used to control grey mould, downy mildew and other fungal pathogens. +Option D: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes. +" A +7858 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCO +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a post-emergence herbicide to control weeds in various cereal crops. +Option B: It is used as a herbicide for the control of various grass and weed seeds. +Option C: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option D: It is used as a herbicide to control grass weeds in cereal crops. +" B +25181547 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=CC(=C1F)C2=NC(=C(C(=C2)N)Cl)C(=O)O)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +Option B: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +Option C: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option D: It is used to control broad-leaved weeds in cereals, normally used as the methyl variant. +" A +16656802 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=CC(=C1F)C2=NC(=C(C(=C2)N)Cl)C(=O)OC)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +Option B: It is used to control broad-leaved weeds in cereals, normally used as the methyl variant. +Option C: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +Option D: It is used for the control of broad-leaved weeds in crops such as maize and soya. +" A +92431 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)OCC#C)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)Cl)F +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for control of grass weeds in cereal crops. +Option B: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option C: It is used as a post-emergence herbicide to control weeds in various cereal crops. +Option D: It is used as a herbicide to control grass weeds in cereal crops. +" B +3031 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1)Cl)C#N)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a pre- or post-emergence herbicide for the control of annual and perennial weeds in rice. +Option B: It is used as a post-emergence herbicide for the control of annual weeds in crops. +Option C: It is used as a pre-emergent and early post-emergent herbicide. +Option D: It is used as a pre- and post-emergence herbicide to control weeds in rice. +" C +4933 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)NC1=CC(=C(C=C1)Cl)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a pre- and post-emergent herbicide for the treatment of grasses and broad-leaved weeds in rice crops. +Option B: It is used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations. +Option C: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +Option D: It is used for the treatment of numerous grasses and broad-leaved weeds in rice, potatoes, and wheat. +" D +91756 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=NC(=NC(=N1)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC)NC +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option B: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +Option C: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +Option D: It is used for the control of broad-leaved weeds in oil seed rape and fodder rape. +" D +15965 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +Option B: It is used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops. +Option C: It is used as a pre- and post-emergent herbicide for the treatment of grasses and broad-leaved weeds in rice crops. +Option D: It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of fruit and root crops. +" B +3034351 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)CN1C2=C(C=CC=C2Cl)SC1=O +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of annual weeds in wheat and oilseed rape. +Option B: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +Option C: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option D: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +" A +93542 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)CSC1=C(C=C(C(=C1)N=C2N3CCCCN3C(=O)S2)F)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +Option B: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +Option C: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option D: It is used to control broad-leaved weeds in cereals, normally used as the methyl variant. +" C +86453 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=NC(=CC2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3Cl)C(=O)OC)F +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option B: It is used for the control of post-emergence control of broad-leaved weeds in soybeans. +Option C: It is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. +Option D: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +" B +11205153 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the treatment of numerous grasses and broad-leaved weeds in rice, potatoes, and wheat. +Option B: It is used for the selective control of grasses and broadleaf weeds primarily in corn. +Option C: It is used for the control of annual grasses and some broad-leaf weeds and is also a growth regulator for control of sprouting in stored potatoes. +Option D: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +" B +56160 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C1=CC=CC=C1S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)Cl)OC +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. +Option B: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +Option C: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option D: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +" D +73674 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of post-emergence control of broad-leaved weeds in soybeans. +Option B: It is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. +Option C: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option D: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +" C +1617113 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used to control annual and perennial grasses in a variety of crops. +Option B: It is used to control annual and perennial grass weeds in a variety of crops. +Option C: It is used for control of grass weeds in cereal crops. +Option D: It is used for the control of annual weeds in crops. +" B +54960 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes. +Option B: It is used as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice. +Option C: It is used for the control of weeds in soya, peanuts, and a variety of vegetable and fruit crops. +Option D: It is used for the control of annual weeds in cereal crops, maize, and rice. +" B +91619 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CP(=O)(CC[C@@H](C(=O)O)N)O +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide to control grass weeds in cereal crops. +Option B: It is used as a herbicide to control annual weeds and grasses. +Option C: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option D: It is used as a post-emergence herbicide to control weeds in various cereal crops. +" B +51556 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)NC(=O)C1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It was specially developed for post-emergence control of broad-leaf weeds in soya. +Option B: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option C: It is used for the control of post-emergence control of broad-leaved weeds in soybeans. +Option D: It is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. +" A +23703973 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C(=C1)Cl)N(C(=O)S2)CC(=O)[O-].[K+] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a post-emergence herbicide for the control of annual weeds in crops. +Option B: It is used as a pre- or post-emergence herbicide for the control of annual and perennial weeds in rice. +Option C: It is used as a post-emergence herbicide to control weeds in various cereal crops. +Option D: It is used as a pre- and post-emergence herbicide to control weeds in rice. +" A +119435 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)O)OC1=C(C=C(C=C1)Cl)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for killing annual and broad leaf weeds. +Option B: It is used for the control of annual and perennial grass weeds in sugar beet. +Option C: It is used for the control of grass weeds in rice. +Option D: It is used for control of grass weeds in cereal crops. +" A +9570991 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)/N=C(/C1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-])\\[O-].[Na+] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It was specially developed for post-emergence control of broad-leaf weeds in soya. +Option B: It is used for the control of post-emergence control of broad-leaved weeds in soybeans. +Option C: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option D: It is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. +" A +137333845 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CP(=O)(CC[C@@H](C(=O)[O-])[NH3+])[O-].[NH4+] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option B: It is used as a herbicide to control annual weeds and grasses. +Option C: It is used as a herbicide to control grass weeds in cereal crops. +Option D: It is used as a post-emergence herbicide to control weeds in various cereal crops. +" B +5484172 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)O)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for control of grass weeds in cereal crops. +Option B: It is used for the control of annual and perennial grass weeds in sugar beet. +Option C: It is used for the control of grass weeds in rice. +Option D: It is used as a herbicide for the control of annual grass weeds in cereal crops. +" B +71714410 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[N+](C)(C)CCO.C1=CC(=C(C=C1Cl)Cl)OCC(=O)[O-] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of annual ryegrass and regionally specific broadleaf weeds. +Option B: It is used as a herbicide to control various broad-leaved weeds. +Option C: It is used for selective control of broadleaf weeds. +Option D: It is used for the post-emergence control of a variety of annual broadleaf weeds. +" C +91739 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C2=NC=C(C=C21)Cl)C(=O)O)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the post-emergence control of weeds in rice, grass, and turf. +Option B: It is used as a pre- or post-emergence herbicide for the control of annual and perennial weeds in rice. +Option C: It is used as a (rather persistent) herbicide for the post-emergence control of weeds in rice, grass, and turf. +Option D: It is used as a pre- and post-emergence herbicide to control weeds in rice. +" A +448979 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)O)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used to control annual and perennial grasses in a variety of crops. +Option B: It is used for control of grass weeds in cereal crops. +Option C: It is used for the control of annual weeds in crops. +Option D: It is used to control annual and perennial grass weeds in a variety of crops. +" A +121596199 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[NH2+]C.C1=CC2=C(C(=C1)Cl)N(C(=O)S2)CC(=O)[O-] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option B: It is used for control of grass weeds in cereal crops. +Option C: It is used for the control of annual weeds in crops. +Option D: It is used to control annual and perennial grass weeds in a variety of crops. +" C +18752 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)NS(=O)(=O)C1=CC=C(C=C1)N +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used mainly for killing bracken. +Option B: It is used as a herbicide mainly for killing bracken. +Option C: It is used as a herbicide (mainly for killing bracken). +Option D: It is used as a herbicide to control grass weeds in cereal crops. +" A +185588 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)Cl)O[C@H](C)C(=O)O +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is the active stereoisomer of the racemic herbicide mecoprop. +Option B: It is used as a herbicide for the control of various grass and weed seeds. +Option C: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option D: It is the major active component of the herbicide indaziflam. +" A +44073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1C(F)(F)F)Cl)OC2=CC(=C(C=C2)[N+](=O)[O-])C(=O)O +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of post-emergence control of broad-leaved weeds in soybeans. +Option B: It is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. +Option C: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option D: It is used for the post-emergence control of a variety of annual broadleaf weeds. +" D +13090847 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC.C1=CC(=C(C2=NC=C(C=C21)Cl)C(=O)O)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a pre- and post-emergence herbicide to control weeds in rice. +Option B: It is used for the post-emergence control of weeds in rice, grass, and turf. +Option C: It is used as a (rather persistent) herbicide for the post-emergence control of weeds in rice, grass, and turf. +Option D: It is used as a pre- or post-emergence herbicide for the control of annual and perennial weeds in rice. +" C +11693711 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N(N1)C)C(=O)C2=C(C=C(C=C2)C(F)(F)F)S(=O)(=O)C +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. +Option B: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option C: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +Option D: It is used as a herbicide to control various broad-leaved weeds. +" D +5759 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1Cl)C(=O)O)Cl)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a post-emergence herbicide to control weeds in various cereal crops. +Option B: It is used as a herbicide to control grass weeds in cereal crops. +Option C: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option D: It is used for control of grass weeds in cereal crops. +" A +13389335 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.[Na+] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option B: It is used as a herbicide to control grass weeds in cereal crops. +Option C: It is used as a herbicide (mainly for killing bracken). +Option D: It is used as a herbicide mainly for killing bracken. +" D +33775 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC1=C(C(=O)N(N=C1)C2=CC=CC(=C2)C(F)(F)F)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used to control grasses and broad-leafed weeds in a variety of crops. +Option B: It is used for the control of broad-leaved weeds and grasses in a variety of crops. +Option C: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +Option D: It is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. +" A +11962742 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1CC2=C([C@@H]1NC3=NC(=NC(=N3)N)[C@@H](C)F)C=C(C=C2)C +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide to control grass weeds in cereal crops. +Option B: It is the major active component of the herbicide indaziflam. +Option C: It is used as a herbicide for the control of various grass and weed seeds. +Option D: It is used as a herbicide for the control of annual grass weeds in cereal crops. +" B +11556911 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used (usually as the corresponding methyl ester proherbicide, fluthiacet-methyl) for the control of broad-leaved weeds in crops such as maize and soya. +Option B: It is used (particularly as its methyl ester, bensulfuron-methyl) as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice. +Option C: It is used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops. +Option D: It is used (particularly in conjunction with the herbicide safener cyprosulfamide) for the control of a wide range of broad-leaved and grassy weeds in corn and other crops. +" D +47491 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of broadleaf weeds in wheat, barley and oats. +Option B: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option C: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +Option D: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +" A +107828 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used (particularly as its methyl ester, bensulfuron-methyl) as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice. +Option B: It is used (usually as the corresponding methyl ester proherbicide, fluthiacet-methyl) for the control of broad-leaved weeds in crops such as maize and soya. +Option C: It is used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops. +Option D: It is used (particularly in conjunction with the herbicide safener cyprosulfamide) for the control of a wide range of broad-leaved and grassy weeds in corn and other crops. +" A +91749 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC2=C(C(=C(C=C2)Cl)C(=O)O)N=C1 +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +Option B: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option C: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +Option D: It is used to control broad-leaved weeds in cereals, normally used as the methyl variant. +" C +91729 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of post-emergence control of broad-leaved weeds in soybeans. +Option B: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +Option C: It is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. +Option D: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +" D +18772468 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCN2C(=O)SC(=NC3=CC(=C(C=C3F)Cl)SCC(=O)O)N2C1 +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used (usually as the corresponding methyl ester proherbicide, fluthiacet-methyl) for the control of broad-leaved weeds in crops such as maize and soya. +Option B: It is used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops. +Option C: It is used (particularly in conjunction with the herbicide safener cyprosulfamide) for the control of a wide range of broad-leaved and grassy weeds in corn and other crops. +Option D: It is used (particularly as its methyl ester, bensulfuron-methyl) as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice. +" A +134123139 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.[K+] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option B: It is used as a herbicide (mainly for killing bracken). +Option C: It is used as a herbicide mainly for killing bracken. +Option D: It is used as a herbicide to control grass weeds in cereal crops. +" B +92389 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)OC2=C(C(=C(C=C2)[N+](=O)[O-])N)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +Option B: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +Option C: It is used as a herbicide against a broad range of weeds in a wide range of crops. +Option D: It is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. +" C +91772 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)O +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option B: It is used for the control of broad-leaved weeds in cereals and oilseed rape. +Option C: It is used to control broad-leaved weeds in cereals, normally used as the methyl variant. +Option D: It is used to control broad-leaved weeds on a range of crops including cereals, rape and beet. +" C +135491728 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC/C(=N\\OC/C=C/Cl)/C1=C(CC(CC1=O)CC(C)SCC)O +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option B: It is used as a post-emergence herbicide to control weeds in various cereal crops. +Option C: It is used as a selective postemergence herbicide for the control of annual and perennial grasses in numerous crops. +Option D: It is used as a post-emergence herbicide for the control of annual weeds in crops. +" C +24685 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC(=O)NC1=CC=CC=C1 +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations. +Option B: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +Option C: It is used as a pre- and post-emergent herbicide for the treatment of grasses and broad-leaved weeds in rice crops. +Option D: It is used for the control of annual grasses and some broad-leaf weeds and is also a growth regulator for control of sprouting in stored potatoes. +" D +16213016 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)OCCON=C(C)C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide to control annual weeds and grasses. +Option B: It is used as a herbicide to control grass weeds in cereal crops. +Option C: It is used as a herbicide for the control of annual grass weeds in cereal crops. +Option D: It is used as systemic herbicide for annual and perennial grasses. +" D +22235201 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=NC(=CC2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3Cl)C(=O)O)F +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of post-emergence control of broad-leaved weeds in soybeans. +Option B: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +Option C: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option D: It is used as a herbicide for the control of post-emergence control of broad-leaved weeds in soybeans. +" D +86369 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)NS(=O)(=O)C)Cl)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used for the control of broad-leaved weeds in crops such as maize and soya. +Option B: It is used as a herbicide for the control of broad-leaved weeds in cereal crops. +Option C: It is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. +Option D: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +" C +32154 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C#C)NC(=O)C1=CC(=CC(=C1)Cl)Cl +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of fruit and root crops. +Option B: It is used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations. +Option C: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops. +Option D: It is used as a pre- and post-emergent herbicide for the treatment of grasses and broad-leaved weeds in rice crops. +" A +38479 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)NC1=C(C=C(C(=C1[N+](=O)[O-])C)C)[N+](=O)[O-] +Question about this molecule: How can the molecule be used as a/an herbicide +Option A: It is used as a herbicide to control various broad-leaved weeds. +Option B: It is used as a post-emergence herbicide for the control of grass and broad-leaved weeds. +Option C: It is used as a herbicide to control broad-leaved weeds in soya and tobacco crops. +Option D: It is used to control most annual grasses and many annual broad-leaved weeds. +" D +1486 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)Cl)OCC(=O)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is an herbicide used to kill weeds on land and in the water. +Option B: It is used as a herbicide for weed control in wheat. +Option C: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option D: It is a selective herbicide used primarily to control weeds in rice crops. +" A +2256 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC1=NC(=NC(=N1)Cl)NC(C)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is an herbicide that does not occur naturally. +Option B: It is a chemical used as an herbicide. +Option C: It is an organic compound commercially available as an herbicide. +Option D: It is used as an herbicide. +" A +54960 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds. +Option B: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option C: It is a selective pre-emergence and post-emergence herbicide that inhibits the formation of acetolactate synthase (ALS inhibitor). +Option D: It is a pre- and post-emergence herbicide for grasses and broad-leaved weed control in various crops. +" C +38479 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)NC1=C(C=C(C(=C1[N+](=O)[O-])C)C)[N+](=O)[O-] +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a preemergent herbicide used to prevent crabgrass from germinating. +Option B: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option C: It is a triazine herbicide recommended for selective control of weeds in wheat and barley. +Option D: It is a selective herbicide used primarily to control weeds in rice crops. +" A +4929 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NC1=NC(=NC(=N1)SC)NC(C)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option B: It is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. +Option C: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option D: It is a selective herbicide which controls annual grasses and broadleaf weeds in a variety of crops including cotton and celery. +" D +8427 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C(=O)O)OC1=C(C=C(C=C1)Cl)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a pre- and post-emergence herbicide for grasses and broad-leaved weed control in various crops. +Option B: It is a chlorophenoxy herbicide similar in structure to 2,4-D that is used to kill annual and perennial broadleaf weeds. +Option C: It is a chlorophenoxy acetic acid herbicide used to defoliate broad-leafed plants. +Option D: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +" B +24743 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)NC1=CC(=CC=C1)OC(=O)NC2=CC=CC=C2 +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective, systemic post-emergence herbicide of the phenyl carbamate and biscarbamate classes. +Option B: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +Option C: It is a selective, postemergence phenoxy herbicide. +Option D: It is a selective herbicide of the carbanilate and biscarbamate classes. +" A +15553 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=NC(=C1Cl)C(=O)O)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option B: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option C: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option D: It is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. +" D +31677 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOCN(C1=C(C=CC=C1CC)CC)C(=O)CCl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is widely used as a selective herbicide worldwide in corn, soybean, and other crop cultures. +Option B: It is a selective herbicide used primarily to control weeds in rice crops. +Option C: It is a selective herbicide used worldwide in corn, soybean and other crop cultures. +Option D: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +" C +4794 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CP(=O)(CCC(C(=O)O)N)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option B: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option C: It is an active ingredient in several nonselective systemic herbicides such as Basta, Rely, Finale, Ignite, Challenge, and Liberty. +Option D: It is used as a herbicide in the cultivation of cereals (wheat, barley and triticale) and can be applied before or after the emergence of the weeds. +" C +3033674 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a triazine herbicide recommended for selective control of weeds in wheat and barley. +Option B: It is a selective herbicide used primarily to control weeds in rice crops. +Option C: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option D: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +" D +73282 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is used as a herbicide in the cultivation of cereals (wheat, barley and triticale) and can be applied before or after the emergence of the weeds. +Option B: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf. +Option C: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option D: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +" A +15546 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)N2C(=O)C(=C(C=N2)N)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is used as a herbicide in the cultivation of cereals (wheat, barley and triticale) and can be applied before or after the emergence of the weeds. +Option B: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option C: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option D: It is a selective herbicide belonging to the group of pyridazone-derivatives, which was put on the market by BASF in the 1960s and used mainly in beet cultivation to control annual broad-leafed weeds. +" D +13263 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC1=NC(=NC(=N1)SC)NC(C)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a herbicide which inhibits photosynthesis and other enzymatic processes. +Option B: It is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. +Option C: It is a selective herbicide used primarily to control weeds in rice crops. +Option D: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +" A +39985 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is used as a selective herbicide. +Option B: It is a widely used herbicide. +Option C: It is a chemical used as an herbicide. +Option D: It is widely used as a herbicide. +" A +1480 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C(=CC(=C1Cl)Cl)Cl)OCC(=O)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +Option B: It is a chlorophenoxy acetic acid herbicide used to defoliate broad-leafed plants. +Option C: It is a chlorophenoxy herbicide similar in structure to 2,4-D that is used to kill annual and perennial broadleaf weeds. +Option D: It is a pre- and post-emergence herbicide for grasses and broad-leaved weed control in various crops. +" B +29393 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN(CCC)C1=C(C=C(C=C1[N+](=O)[O-])S(=O)(=O)N)[N+](=O)[O-] +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is widely used as a herbicide. +Option B: It is used as a selective herbicide. +Option C: It is a pre-emergence surface-applied herbicide. +Option D: It is a widely used herbicide. +" C +91770 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(N=C1)C2=NC(C(=O)N2)(C)C(C)C)C(=O)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a widely used herbicide. +Option B: It is used as an herbicide. +Option C: It is used as a selective herbicide. +Option D: It is a chemical used as an herbicide. +" D +7153 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)Cl)OC(C)C(=O)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a chemical used as an herbicide. +Option B: It is a widely used herbicide. +Option C: It is used as an herbicide. +Option D: It is used as a selective herbicide. +" C +4937 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NC1=NC(=NC(=N1)Cl)NC(C)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. +Option B: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option C: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option D: It is an herbicide used for control of broadleaf weeds and annual grasses in sweet sorghum. +" D +9411 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(C)N1C(=O)C(=C(NC1=O)C)Br +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a chemical used as an herbicide. +Option B: It is widely used as a herbicide. +Option C: It is an organic compound commercially available as an herbicide. +Option D: It is used as an herbicide. +" C +91756 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=NC(=NC(=N1)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC)NC +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option B: It is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. +Option C: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option D: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +" D +9502 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C(=O)NC1=CC(=C(C=C1)Cl)Cl)OC +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a widely used herbicide. +Option B: It is used as an herbicide. +Option C: It is a chemical used as an herbicide. +Option D: It is used as a selective herbicide. +" B +7551 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC(=C1)Cl)NC(=O)OCC#CCCl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is widely used as a herbicide. +Option B: It is a chemical used as an herbicide. +Option C: It is used as a selective herbicide. +Option D: It is a widely used herbicide. +" C +92431 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)OCC#C)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)Cl)F +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is used as a herbicide for weed control in wheat. +Option B: It is a selective herbicide used primarily to control weeds in rice crops. +Option C: It is a triazine herbicide recommended for selective control of weeds in wheat and barley. +Option D: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +" A +1988 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC=CC(=C1N(COCC)C(=O)CCl)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is used as an herbicide. +Option B: It is an herbicide developed by Monsanto and Zeneca. +Option C: It is a chemical used as an herbicide. +Option D: It is an organic compound commercially available as an herbicide. +" B +7847 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC=O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is used as a herbicide for weed control in wheat. +Option B: It is an herbicide and algicide used in water treatment. +Option C: It is a selective herbicide used primarily to control weeds in rice crops. +Option D: It is an herbicide used to kill weeds on land and in the water. +" B +27189 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C(=O)C(C)OC1=CC=CC2=CC=CC=C21 +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is widely used as a herbicide. +Option B: It is a widely used herbicide. +Option C: It is used as a selective herbicide. +Option D: It is a selective systemic amide herbicide. +" D +15965 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option B: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option C: It is a herbicide used for killing annual and perennial broad-leaf weeds to aid in brush and grass control mainly in non-cropping situations. +Option D: It is a persistent systemic herbicide used for general woody plant control and broad-leaved weeds on non-crop and utility areas. +" D +4931 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)N(C1=CC=CC=C1)C(=O)CCl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective herbicide used primarily to control weeds in rice crops. +Option B: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option C: It is widely used as a selective herbicide worldwide in corn, soybean, and other crop cultures. +Option D: It is a selective herbicide used worldwide in corn, soybean and other crop cultures. +" C +1489 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf. +Option B: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option C: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option D: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds. +" B +92434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective postemergence sulfonylurea herbicide for the control of annual and perennial broadleaf weeds and grasses in sugar beets (Beta vulgaris). +Option B: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf. +Option C: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option D: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds. +" A +52999 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective postemergence sulfonylurea herbicide for the control of annual and perennial broadleaf weeds and grasses in sugar beets (Beta vulgaris). +Option B: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf. +Option C: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option D: It is a residual sulfonylurea herbicide that kills broadleaf weeds and some annual grasses. +" D +33360 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a herbicide for annual grass and annual broad-leaved weed control in maize, potatoes, and other crops. +Option B: It is a persistent systemic herbicide used for general woody plant control and broad-leaved weeds on non-crop and utility areas. +Option C: It is a pre- and post-emergence herbicide for grasses and broad-leaved weed control in various crops. +Option D: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +" C +86137 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C1(C(=O)NC(=N1)C2=C(C=C(C=N2)COC)C(=O)O)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a systemic herbicide that moves throughout the plant tissue and prevents plants from producing an essential enzyme, acetolactate synthase (ALS), which is not found in animals. +Option B: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf. +Option C: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option D: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +" A +30773 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC1=NC(=NC(=N1)Cl)NC(C)(C)C#N +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option B: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +Option C: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf. +Option D: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds. +" D +93542 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)CSC1=C(C=C(C(=C1)N=C2N3CCCCN3C(=O)S2)F)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds. +Option B: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf. +Option C: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +Option D: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds. +" B +5216 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC1=NC(=NC(=N1)Cl)NCC +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a herbicide of the triazine class. +Option B: It is a widely used herbicide. +Option C: It is used as a selective herbicide. +Option D: It is widely used as a herbicide. +" A +54739 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective herbicide used primarily to control weeds in rice crops. +Option B: It is a selective herbicide used worldwide in corn, soybean and other crop cultures. +Option C: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option D: It is widely used as a selective herbicide worldwide in corn, soybean, and other crop cultures. +" C +33775 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC1=C(C(=O)N(N=C1)C2=CC=CC(=C2)C(F)(F)F)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is an herbicide used for control of broadleaf weeds and annual grasses in sweet sorghum. +Option B: It is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. +Option C: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds. +Option D: It is a pyridazinone herbicide used to control grass and broadleaf weeds. +" D +4928 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NC1=NC(=NC(=N1)OC)NC(C)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a persistent systemic herbicide used for general woody plant control and broad-leaved weeds on non-crop and utility areas. +Option B: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option C: It is a herbicide used for killing annual and perennial broad-leaf weeds to aid in brush and grass control mainly in non-cropping situations. +Option D: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops. +" C +13878 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC1=NC(=NC(=N1)N)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is widely used as a herbicide. +Option B: It is used as a selective herbicide. +Option C: It is a herbicide of the triazine class. +Option D: It is a widely used herbicide. +" C +50897 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is widely used as a herbicide. +Option B: It is used as a selective herbicide. +Option C: It is a widely used herbicide. +Option D: It is a chemical used as an herbicide. +" B +7207 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)Cl)OCCCC(=O)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a powerful, selective, widely used phenoxy herbicide. +Option B: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +Option C: It is a phenoxybutyric herbicide. +Option D: It is a selective, postemergence phenoxy herbicide. +" C +86222 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option B: It is a selective herbicide used for control of broadleaf weeds, especially thistles and clovers. +Option C: It is an herbicide used for control of broadleaf weeds and annual grasses in sweet sorghum. +Option D: It is a contact herbicide used to control broadleaf and sedge weeds in cereals. +" D +47491 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is used as a herbicide for weed control in wheat. +Option B: It is a selective herbicide used primarily to control weeds in rice crops. +Option C: It is a triazine herbicide recommended for selective control of weeds in wheat and barley. +Option D: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +" C +54738 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C1(C(=O)NC(=N1)C2=C(C=CC=N2)C(=O)O)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective herbicide used primarily to control weeds in rice crops. +Option B: It is a triazine herbicide recommended for selective control of weeds in wheat and barley. +Option C: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option D: It is a non-selective herbicide for non-crop land applications. +" D +4169 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC=CC(=C1N(C(C)COC)C(=O)CCl)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a widely used herbicide. +Option B: It is a chemical used as an herbicide. +Option C: It is widely used as a herbicide. +Option D: It is used as a selective herbicide. +" C +32154 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C#C)NC(=O)C1=CC(=CC(=C1)Cl)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a widely used herbicide. +Option B: It is used as a selective herbicide. +Option C: It is widely used as a herbicide. +Option D: It is a chemical used as an herbicide. +" B +91739 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C2=NC=C(C=C21)Cl)C(=O)O)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective herbicide used worldwide in corn, soybean and other crop cultures. +Option B: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option C: It is widely used as a selective herbicide worldwide in corn, soybean, and other crop cultures. +Option D: It is a selective herbicide used primarily to control weeds in rice crops. +" D +6423 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([N+](=O)[O-])(Cl)(Cl)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a widely used herbicide. +Option B: It is a chemical compound used as a broad-spectrum herbicide. +Option C: It is used as a selective herbicide. +Option D: It is widely used as a herbicide. +" B +3083546 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)COC1=C(C=C(C(=C1)N2C(=O)C(=C(C=N2)C(F)(F)F)C)F)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is primarily used as a herbicide to control weed growth on lawns and turf fields. +Option B: It is a contact herbicide used to control broadleaf and sedge weeds in cereals. +Option C: It is a selective herbicide used primarily to control weeds in rice crops. +Option D: It is a contact herbicide for use on potatoes, maize, soya, and wheat. +" D +41428 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C(=NC(=C1Cl)Cl)OCC(=O)O)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a systemic, foliar herbicide in the pyridine group for perennial broad-leaved and woody weed control. +Option B: It is a persistent systemic herbicide used for general woody plant control and broad-leaved weeds on non-crop and utility areas. +Option C: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option D: It is a herbicide used for killing annual and perennial broad-leaf weeds to aid in brush and grass control mainly in non-cropping situations. +" A +50465 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)O)OC1=NC(=C(C(=C1Cl)N)Cl)F +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a chemical used as an herbicide. +Option B: It is an herbicide in the class of synthetic auxins. +Option C: It is used as an herbicide. +Option D: It is an organic compound commercially available as an herbicide. +" B +91779 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCS(=O)(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a herbicide for annual grass and annual broad-leaved weed control in maize, potatoes, and other crops. +Option B: It is a selective herbicide for the control of wild mustard, stinkweed, and other broad-leaved weeds especially in canola. +Option C: It is a persistent systemic herbicide used for general woody plant control and broad-leaved weeds on non-crop and utility areas. +Option D: It is a pre- and post-emergence herbicide for grasses and broad-leaved weed control in various crops. +" A +24744 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC=C1)NC(=O)OC2=CC=CC(=C2)NC(=O)OC +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective, systemic post-emergence herbicide of the phenyl carbamate and biscarbamate classes. +Option B: It is a selective herbicide of the carbanilate and biscarbamate classes. +Option C: It is a selective, postemergence phenoxy herbicide. +Option D: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +" B +91744 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CSC(=C1N(C(C)COC)C(=O)CCl)C +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a chemical used as an herbicide. +Option B: It is a widely used herbicide. +Option C: It is used as a selective herbicide. +Option D: It is widely used as a herbicide. +" B +86369 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)NS(=O)(=O)C)Cl)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a chemical used as an herbicide. +Option B: It is used as a selective herbicide. +Option C: It is used as an herbicide. +Option D: It is a widely used herbicide. +" A +53518 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a powerful, selective, widely used phenoxy herbicide. +Option B: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +Option C: It is a selective herbicide used primarily to control weeds in rice crops. +Option D: It is a selective, postemergence phenoxy herbicide. +" D +7204 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)Cl)OCC(=O)O +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a selective, postemergence phenoxy herbicide. +Option B: It is a powerful, selective, widely used phenoxy herbicide. +Option C: It is a selective phenoxy herbicide used for postemergence control of annual and perennial grass weeds. +Option D: It is a selective herbicide used primarily to control weeds in rice crops. +" B +16653 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCSC(=O)N1CCCCCC1 +Question about this molecule: Which kind of herbicide is this molecule? +Option A: It is a chemical used as an herbicide. +Option B: It is a widely used herbicide. +Option C: It is widely used as a herbicide. +Option D: It is used as a selective herbicide. +" D +667490 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1)C(=S)N=CN2 +Question about this molecule: Which kind of immunosuppressive agent is this molecule? +Option A: It is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent. +Option B: It is a macrocyclic antibiotic with potent immunosuppressive activity that is used alone or in combination with calcineurin inhibitors and corticosteroids to prevent cellular rejection after renal transplantation. +Option C: It is an antineoplastic and immunosuppressive agent widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis and rheumatoid arthritis. +Option D: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +" A +9782 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C +Question about this molecule: Which kind of immunosuppressive agent is this molecule? +Option A: It displays immunosuppresive and anti-angiogenic activity. +Option B: It is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. +Option C: It is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent. +Option D: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +" B +126941 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: Which kind of immunosuppressive agent is this molecule? +Option A: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option B: It is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent. +Option C: It is a macrocyclic antibiotic with potent immunosuppressive activity that is used alone or in combination with calcineurin inhibitors and corticosteroids to prevent cellular rejection after renal transplantation. +Option D: It is an antineoplastic and immunosuppressive agent widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis and rheumatoid arthritis. +" D +445643 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC +Question about this molecule: Which kind of immunosuppressive agent is this molecule? +Option A: It is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent. +Option B: It is a macrocyclic antibiotic with potent immunosuppressive activity that is used alone or in combination with calcineurin inhibitors and corticosteroids to prevent cellular rejection after renal transplantation. +Option C: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option D: It is an antineoplastic and immunosuppressive agent widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis and rheumatoid arthritis. +" C +5284616 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC +Question about this molecule: Which kind of immunosuppressive agent is this molecule? +Option A: It is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent. +Option B: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option C: It is a macrocyclic antibiotic with potent immunosuppressive activity that is used alone or in combination with calcineurin inhibitors and corticosteroids to prevent cellular rejection after renal transplantation. +Option D: It is an antineoplastic and immunosuppressive agent widely used in the therapy of leukemia, lymphoma, solid tumors, psoriasis and rheumatoid arthritis. +" C +5426 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O +Question about this molecule: Which kind of immunosuppressive agent is this molecule? +Option A: It is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. +Option B: It is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent. +Option C: It displays immunosuppresive and anti-angiogenic activity. +Option D: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +" C +13970960 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)[C@@H](C)CC(=O)CC(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +13854967 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]1(CCC[C@]2([C@H]1CC[C@@]([C@@H]2CCO)(C)O)C)CO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase 1 inhibitor and a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor. +" B +5281404 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=CC2=C1NC3=CC=CC=C23 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a monoamine oxidase inhibitor. +Option B: It is a reversible monoamine oxidase inhibitor. +Option C: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +Option D: It is a specific, reversible inhibitor of monoamine oxidase A. +" D +5481948 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C=CC2=C(O1)C(=CC(=C2)C3=COC4=CC(=CC(=C4C3=O)O)O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.1.1.21 (aldehyde reductase) inhibitor. +Option B: It is an EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor. +Option C: It is an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" A +464205 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is a HIV-1 integrase inhibitor. +Option C: It is an inhibitor of HIV-1 reverse transcriptase. +Option D: It is a HIV-1 reverse transcriptase inhibitor. +" C +12441 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC2=CC3=C(C4=C2[C@@H]1CC5=C4C(=C(C=C5)OC)O)OCO3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. +Option B: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option C: It is an EC 1.4.3.22 (diamine oxidase) inhibitor and an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +Option D: It is an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +" C +480859 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C(C2=C(C=C1O)OC[C@H](C2)C3=C(C=C(C=C3)O)O)OC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option D: It is an EC 1.14.14.14 (aromatase) inhibitor. +" C +5368642 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)/C=C/C=C/C(=C/C=C/C=C/C1=CC=CC=C1)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a lipoxygenase inhibitor and a platelet aggregation inhibitor. +Option B: It is a leukocyte elastase inhibitor. +Option C: It is a platelet aggregation inhibitor. +Option D: It is a neprilysin inhibitor. +" A +5318997 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=C(C2=O)C(=CC(=C3CC=C(C)C)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C5=CC=C(C=C5)OC)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor. +Option B: It is a 3',5'-cyclic-GMP phosphodiesterase inhibitor. +Option C: It is an EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor. +Option D: It is a phosphodiesterase inhibitor. +" B +12086047 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)OC[C@@H](C(=O)O)N)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cystathionine gamma-synthase inhibitor. +Option B: It is a cysteine protease inhibitor. +Option C: It is a protease inhibitor. +Option D: It is a leukocyte elastase inhibitor. +" A +107905 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is an EC 4.2.1.1 (carbonic anhydrase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an alpha-amylase inhibitor. +" D +449215 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H](C(=O)NO1)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor. +Option B: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +Option C: It is a serine C-palmitoyltransferase inhibitor. +Option D: It is an EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor. +" C +9905947 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C2=C(C1=O)C(=CC(=C2)O)O)C/C=C(\\C)/CCC=C(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase inhibitor. +Option B: It is a tyrosine-kinase inhibitor. +Option C: It is a protein-tyrosine-phosphatase inhibitor. +Option D: It is a tyrosinase inhibitor. +" C +10083434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=C(C(=C1O)O)C(=O)C(=O)C(=C2O)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is an HIV protease inhibitor. +Option C: It is a HIV-1 integrase inhibitor. +Option D: It is a protease inhibitor. +" D +10315101 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@@]2([C@@H]([C@@]1(C)CCC(CCO)CO)CCC=C2C(=O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 1 inhibitor. +Option B: It is a lipoxygenase inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor. +Option D: It is a cyclooxygenase inhibitor. +" B +61482 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: O.O.Cl[Cu]Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.166 (heparanase) inhibitor. +Option B: It is an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor. +Option C: It is an EC 3.4.21.5 (thrombin) inhibitor. +Option D: It is a cholestenol Delta-isomerase inhibitor. +" D +11250133 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](OC2=C1C(=CC(=C2[C@@H]3[C@H]([C@H](OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an ACE inhibitor. +Option B: It is an mTOR inhibitor. +Option C: It is a thrombin inhibitor. +Option D: It is an ALS inhibitor. +" C +5359485 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC2=C1C3=C(C(=CC(=C3)O)O)C(=O)O2)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a P-Glycoprotein Inhibitor. +Option B: It is a Neuraminidase Inhibitor. +Option C: It is a Cholinesterase Inhibitor. +Option D: It is an Intestinal Lipase Inhibitor. +" C +9866696 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C(=C1)O)C(=O)C3=C(C2[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)C=C(C=C3O)CO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor. +Option B: It is a tyrosinase inhibitor. +Option C: It is a tyrosine kinase inhibitor. +Option D: It is a tyrosine-kinase inhibitor. +" B +16741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CCN=C=S +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an aldehyde dehydrogenase (NAD(+)) inhibitor. +Option B: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option C: It is an aldehyde dehydrogenase 1a2 (ALDH1a2) inhibitor. +Option D: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +" A +13918473 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C[C@@H]1O)[C@@H]2[C@H](C(=C)C(=O)O2)CCC(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitrification inhibitor. +Option B: It is a nitric oxide synthase inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It acts as a DNA synthesis inhibitor. +" B +70678751 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C[C@@H](C(=O)NCCCCNCCCN)NC(=O)C2C(O2)C(=O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of neuronal activity. +Option B: It is an inhibitor of NS5A. +Option C: It is an inhibitor of cellular mitosis. +Option D: It is an inhibitor of cysteine proteinases. +" D +3083548 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=C4C=C(C=C5)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a serotonin and norepinephrine reuptake inhibitor. +Option B: It is a serotonin uptake inhibitor. +Option C: It is a selective norepinephrine reuptake inhibitor. +Option D: It is a norepinephrine-dopamine reuptake inhibitor (NDRI). +" B +11355692 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C[C@@]1(CC(=CC1=O)NC=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor. +Option B: It is a tyrosine-kinase inhibitor. +Option C: It is a tyrosinase inhibitor. +Option D: It is a tyrosine kinase inhibitor. +" C +64715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)C(=O)O[C@H]1CCC=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an antineoplastic enzyme inhibitor. +Option B: It is an angiotensin-converting enzyme (ACE) inhibitor. +Option C: It is an angiogenesis and metastasis inhibitor. +Option D: It is an anthrax lethal factor endopeptidase inhibitor. +" D +5326150 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[N+]1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a P-Glycoprotein Inhibitor. +Option B: It is a Cholinesterase Inhibitor. +Option C: It is an Intestinal Lipase Inhibitor. +Option D: It is a Neuraminidase Inhibitor. +" B +22179 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C2C[C@H]3C4=C(C2=C1)C(=C(C=C4CCN3)O)OC)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 integrase inhibitor. +Option B: It is a HIV-1 reverse transcriptase inhibitor. +Option C: It is a HIV-1 protease inhibitor. +Option D: It is an HIV protease inhibitor. +" A +446512 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@@H]([C@@H]3C(=C)[C@H]([C@H]4[C@H](O3)CC[C@]5(O4)CC[C@@H](O5)/C=C/[C@@H](C)[C@@H]6CC(=C[C@@]7(O6)[C@@H](CC[C@H](O7)C[C@](C)(C(=O)O)O)O)C)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor and an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option B: It is an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option C: It is an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor. +Option D: It is an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor. +" D +173651 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C=CC2=CCC[C@@H]([C@@H]2[C@H]1CC[C@@H]3C[C@H](CC(=O)O3)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor. +Option C: It is an EC 1.1.1.21 (aldehyde reductase) inhibitor. +Option D: It is an EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor. +" B +25017463 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]\\1C[C@@H](OC(=O)C[C@@H](NC(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@H](C/C(=C1)/CO)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an HIV protease inhibitor. +Option B: It is an HIV fusion inhibitor. +Option C: It is an actin polymerisation inhibitor. +Option D: It is an actin assembly inhibitor. +" C +14213209 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=CC(=C1)O)C2=CC3=C(O2)C=CC(=C3)CCCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a mitogen-activated protein kinase inhibitor. +Option B: It is a NF-kappaB inhibitor. +Option C: It is a kinase inhibitor. +Option D: It is a potent protein kinase C inhibitor. +" B +10322911 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@@](C[C@H]1[C@@]3(CC[C@]4(C5=CC(=C(C(=C5C(=O)C=C4[C@]3(CC2)C)C=O)O)O)C)C)(C)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor. +Option B: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +Option C: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. +Option D: It is an EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor. +" B +443629 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@H]1N[C@H]2C=C([C@H]([C@@H]([C@H]2O)O)O)CO)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)CO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.4.1.231 [alpha,alpha-trehalose phosphorylase (configuration-retaining)] inhibitor. +Option B: It is an EC 2.4.2.4 (thymidine phosphorylase) inhibitor. +Option C: It is an EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor. +Option D: It is an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. +" A +10477690 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C[C@H]2[C@@]3(CCC(=O)C([C@H]3CC[C@@]2([C@]4([C@@]1(C(=C(C4=O)C)O)C)C(=O)OC)C)(C)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a NAD(+) ADP-ribosyltransferase inhibitor. +Option B: It is an EC 2.5.1.58 (protein farnesyltransferase) inhibitor. +Option C: It is an EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor. +Option D: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. +" B +439501 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of the NA(+)-K(+)-exchanging ATPase. +Option B: It is an EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor. +Option C: It is an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. +Option D: It is an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor. +" C +100217 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H]1C[C@@H]2C[C@@H]3[C@H]1N(C2)CCC4=C3NC5=CC=CC=C45 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +10378172 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C/C1=C(C(=C(C(=C1O)C(=O)N)C(=O)O)OC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor. +Option B: It is an EC 1.1.1.21 (aldehyde reductase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor. +" B +5276375 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC[C@@H](C)C1=C(C(=O)[C@H]2[C@H]([C@]1(C)C(=O)/C=C\\O)[C@H](C[C@H]([C@H]2O)C)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor. +Option B: It is an EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor. +Option C: It is an EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor. +Option D: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +" A +444899 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.1 (carboxylesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" C +3415 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)(O)P(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 integrase inhibitor. +Option B: It is a sodium-dependent Pi-transporter inhibitor and a HIV-1 reverse transcriptase inhibitor. +Option C: It is a HIV-1 reverse transcriptase inhibitor and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option D: It is a HIV-1 reverse transcriptase inhibitor. +" B +560193 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C(=O)NC)SCCSP(=O)(OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" B +5284462 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(OC)O/C(=C\\Cl)/C1=CC(=C(C=C1Cl)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" D +5372405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNP(=S)(OC)O/C(=C/C(=O)OC(C)C)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" A +17040 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)OC(=O)NC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" B +15134 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCCCNC(=O)C(Cl)Cl)CCCNC(=O)C(Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option B: It is an EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor. +Option C: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +Option D: It is an aldehyde dehydrogenase 1a2 (ALDH1a2) inhibitor. +" D +15134 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCCCNC(=O)C(Cl)Cl)CCCNC(=O)C(Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +Option B: It is an aldehyde dehydrogenase 1a2 (ALDH1a2) inhibitor. +Option C: It is an aldehyde dehydrogenase (NAD(+)) inhibitor. +Option D: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +" D +14322 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC=C1)OC(=O)NC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" A +17522 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=S)(OC)OC1=CC=C(C=C1)C#N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 2.5.1.18 (glutathione transferase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an acetylcholinesterase (AChE) inhibitor. +" C +997 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CC(=O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as an acetyl-CoA carboxylase inhibitor. +Option B: It is an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor. +Option C: It is a pyruvate carboxylase inhibitor. +Option D: It is an EC 6.4.1.1 (pyruvate carboxylase) inhibitor. +" D +5478 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)NCC(COC1=NSN=C1N2CCOCC2)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a competitive inhibitor. +Option B: It is a beta-adrenergic antagonist. +Option C: It is a mitotic inhibitor. +Option D: It is a vitamin K antagonist. +" B +23717 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCOP(=O)(OCCC)OC1=CC=C(C=C1)SC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" B +11334308 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)CNC2=CC=CC=C2C(=O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase inhibitor. +Option C: It is a lipoxygenase inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" C +5330 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.4 (amidase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. +Option D: It is an EC 3.5.1.23 (ceramidase) inhibitor. +" C +5363137 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C\\C=C\\C(=C\\C(=O)O)\\C)/C=C/C12C(CCCC1(O2)C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a L-amino-acid oxidase inhibitor. +Option B: It acts as an aromatic-L-amino-acid decarboxylase inhibitor. +Option C: It is an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. +Option D: It is an EC 4.1.1.17 (ornithine decarboxylase) inhibitor. +" D +3696 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CCCN1C2=CC=CC=C2CCC3=CC=CC=C31 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor. +Option B: It is a metalloendopeptidase inhibitor. +Option C: It is an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. +Option D: It is a prolyl oligopeptidase inhibitor. +" C +14259001 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C2C(=C(C=C1O)O)C(=O)C[C@H](O2)C3=CC(=C(C=C3)OC)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a breast cancer resistance protein inhibitor. +Option B: It is a protease inhibitor. +Option C: It is a cysteine protease inhibitor. +Option D: It is a leukocyte elastase inhibitor. +" A +5368008 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(/C(=N\\OC(=O)NC)/C)SC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +158311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C(=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option B: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor. +Option C: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option D: It is an EC 3.2.1.166 (heparanase) inhibitor. +" C +57390614 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC(=C3C(=C2)OC(=C(C3=O)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)O)C5=CC=C(C=C5)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor. +Option B: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option C: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option D: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor. +" A +31099 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)OC1=CC=CC(=C1)N=CN(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +5280953 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor. +Option B: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option C: It is an EC 1.4.3.4 (monoamine oxidase) inhibitor. +Option D: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. +" C +1981 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option C: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option D: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +" C +71771 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option C: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +Option D: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +" D +99470 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CCCC(C)CO)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.1 (carboxylesterase) inhibitor. +" D +4797 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)NO)OP(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option B: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option C: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +Option D: It is an EC 5.3.1.1 (triose-phosphate isomerase) inhibitor. +" D +5360460 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)O/N=C(/C#N)\\C1=CC=CC=C1 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" A +98888 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN1CCNCCN +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.22.52 (calpain-1) inhibitor and an EC 3.4.22.53 (calpain-2) inhibitor. +Option B: It is an EC 3.4.21.37 (leukocyte elastase) inhibitor and an EC 3.4.21.64 (peptidase K) inhibitor. +Option C: It is an EC 3.4.22.53 (calpain-2) inhibitor. +Option D: It is an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. +" D +14412552 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)C(=O)C1=C(C=C(C=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase 1 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor. +" C +9929833 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C(C2=C(N1)C=C(C=C2)OC)C[C@H]3C(=O)N4CCC[C@H]4C(=O)N3)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a leukocyte elastase inhibitor. +Option B: It is a protease inhibitor. +Option C: It is a cysteine protease inhibitor. +Option D: It is a breast cancer resistance protein inhibitor. +" D +5283446 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC/C=C\\C/C=C\\CCCCCCCC(=O)NCCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is a fatty acid amide hydrolase inhibitor. +Option C: It is an EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor. +Option D: It is an EC 3.5.1.4 (amidase) inhibitor. +" C +9884642 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OCCCCO[N+](=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option B: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +Option C: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" A +147299 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H]([C@H](OC2=C1C(=CC(=C2[C@H]3[C@@H]([C@H](OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option B: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor. +Option C: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option D: It is a DNA topoisomerase (ATP-hydrolysing) inhibitor. +" A +60172 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC(=C2C(=N1)N(C=N2)CCOCP(=O)(O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is a HIV-1 reverse transcriptase inhibitor. +Option C: It is an HIV protease inhibitor. +Option D: It is a HIV-1 integrase inhibitor. +" B +92431 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)OCC#C)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)Cl)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It acts as an acetyl-CoA carboxylase inhibitor. +Option C: It is an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor. +" C +11274280 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC(=C(C=C4)O)O)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COC(=O)/C=C/C6=CC(=C(C=C6)O)O)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. +Option B: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. +Option C: It is an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. +Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +" C +72193702 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC2=C(C=C1)N(C=C2CC(=O)NO)C(=O)C3=CC=C(C=C3)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +Option B: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option C: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" B +161597 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[Se](=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.98 (histone deacetylase) inhibitor. +Option B: It is a histone deacetylase inhibitor. +Option C: It is an inhibitor of histone deacetylase (HDAC). +Option D: It is an oral histone deacetylase inhibitor and antineoplastic agent. +" A +10364 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)C(C)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of cellular mitosis. +Option B: It is an inhibitor of NS5A. +Option C: It is an inhibitor of bacterial growth. +Option D: It is an inhibitor of unwanted bacteria. +" C +50900934 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCC(=O)O[C@H]1[C@@H](O[C@H]([C@@H]([C@@H]1O)OC(=O)/C=C/C2=CC=CC=C2)O[C@H]3[C@@H](O[C@H]([C@@H]([C@@H]3OC(=O)CCCCCCCCC)O)O[C@H]4[C@@H](O[C@@H]5[C@@H]([C@@H]4O)OC(=O)CCCCCCCCC[C@@H](O[C@H]6[C@H](O5)[C@H]([C@H]([C@H](O6)C)O)O)CCCCC)C)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase 1 inhibitor and a cyclooxygenase 2 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +" C +637229 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H](C(=O)C5(C)C)O)C)C)[C@@H]2[C@]1(C)O)C)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 integrase inhibitor. +Option B: It is a HIV-1 reverse transcriptase inhibitor. +Option C: It is a HIV-1 protease inhibitor. +Option D: It is an HIV protease inhibitor. +" D +70697917 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC(C)(C)[C@@H](COC1=C2C(=C(C3=C1OC(=O)C=C3)OC)C=CO2)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option B: It is an arachidonate 5-lipoxygenase inhibitor. +Option C: It is an arachidonate 12-lipoxygenase inhibitor. +Option D: It is an arachidonate 5-lipoxygenase inhibitor and a cyclooxygenase 2 inhibitor. +" D +3346 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)OP(=S)(OC)OC)SC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an acetylcholinesterase (AChE) inhibitor. +Option C: It is an acetylcholinesterase inhibitor and a cholinesterase inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" C +51041990 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C(C=C(C=C1O)OC)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a breast cancer resistance protein inhibitor. +Option B: It is a cysteine protease inhibitor. +Option C: It is a leukocyte elastase inhibitor. +Option D: It is a protease inhibitor. +" A +167298 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@H]([C@@H](C(=O)COP(=O)(O)O)O)O)OP(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a pyruvate carboxylase inhibitor. +Option B: It is an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor. +Option C: It is a ribulose-bisphosphate carboxylase inhibitor. +Option D: It is an EC 6.4.1.1 (pyruvate carboxylase) inhibitor. +" C +11360765 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC(=O)C1=C(C=C(C=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a lipoxygenase inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" A +352864 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CSCCC(C(=O)NO)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is a ligases forming aminoacyl tRNA and related compounds inhibitor. +Option C: It acts as a DNA synthesis inhibitor. +Option D: It is a competitive inhibitor. +" B +46907933 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCC/C=C\\CCCCCCCC(=O)O[C@H](CC(=O)[O-])C[N+](C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a glycine transporter 2 inhibitor. +Option B: It is a tyrosinase inhibitor. +Option C: It is a protein-tyrosine-phosphatase inhibitor. +Option D: It is a tyrosine-kinase inhibitor. +" A +86306 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)CSC1=NC(=NN1C(=O)N(C)C)C(C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase (AChE) inhibitor. +" B +91756 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=NC(=NC(=N1)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC)NC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an ATP synthase inhibitor. +Option C: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +Option D: It is an acetolactate synthase inhibitor. +" D +39941 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC2=C(C=C1)OC(=N2)C3=CC=C(C=C3)Cl)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an arachidonate 5-lipoxygenase inhibitor and a cyclooxygenase 2 inhibitor. +Option B: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option C: It is an arachidonate 5-lipoxygenase inhibitor. +Option D: It is an arachidonate 12-lipoxygenase inhibitor. +" C +999 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor. +Option B: It is a pyruvate carboxylase inhibitor. +Option C: It is an EC 6.4.1.1 (pyruvate carboxylase) inhibitor. +Option D: It acts as an acetyl-CoA carboxylase inhibitor. +" B +5282309 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N(C)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor. +Option B: It is a selective tyrosine kinase receptor inhibitor. +Option C: It is a tyrosine kinase inhibitor. +Option D: It is a sphingosine kinase inhibitor. +" D +11198769 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCC(=O)NCC1=CC=CC=C1 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option B: It is a fatty acid amide hydrolase inhibitor. +Option C: It is an EC 3.5.1.4 (amidase) inhibitor. +Option D: It is an EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor. +" B +93516 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OC1=CN=C(N=C1)C(C)(C)C)OC(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase (AChE) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" B +132971 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option B: It is an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +Option C: It is an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. +Option D: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. +" D +45375808 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a hepatitis C virus nonstructural protein 5A inhibitor. +Option B: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. +Option C: It is a hepatitis C protease inhibitor. +Option D: It is a nonnucleoside hepatitis C virus polymerase inhibitor. +" C +4261 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC(=O)OCC3=CN=CC=C3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a histone deacetylase inhibitor. +Option B: It is an EC 3.5.1.98 (histone deacetylase) inhibitor. +Option C: It is an inhibitor of histone deacetylase (HDAC). +Option D: It is an oral histone deacetylase inhibitor and antineoplastic agent. +" B +5329103 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\\2/C3=C(C=CC(=C3)Cl)NC2=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. +Option B: It is a tyrosine kinase inhibitor. +Option C: It is a tyrosine kinase receptor inhibitor. +Option D: It is a selective tyrosine kinase receptor inhibitor. +" A +57397583 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@H]([C@H](O[C@H]2OC3=C(OC4=CC(=CC(=C4C3=O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)C6=CC=C(C=C6)O)CO)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option B: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor. +Option C: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option D: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor. +" B +5842956 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)S/C(=C(/C(=C(/SC2=CC=CC=C2)\\N)/C#N)\\C#N)/N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a mitogen-activated protein kinase inhibitor. +Option B: It is a potent protein kinase C inhibitor. +Option C: It is a potent, selective, and cell-permeable protein kinase C inhibitor. +Option D: It acts as an inhibitor of MEK (mitogen activated protein kinase kinase). +" D +148177 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. +Option B: It is a phosphatidylinositol 3-kinase inhibitor. +Option C: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor. +Option D: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +" A +90479 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC(=O)C1=CC=CC=C1OP(=S)(N)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" B +4362 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1C(=O)C=CC1=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor. +Option B: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option C: It is an EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor. +Option D: It is an EC 1.14.14.14 (aromatase) inhibitor. +" C +86453 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=NC(=CC2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3Cl)C(=O)OC)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an ATP synthase inhibitor. +Option C: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +Option D: It is an acetolactate synthase inhibitor. +" C +11652416 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C(/C=O)\\[C@@H](CC=O)CC(=O)OCCC1=CC=C(C=C1)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" A +60825 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option D: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +" C +56600473 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCC/C=C\\CCCCCCCC(=O)OCCCC1=CC2=C(C=C1)OC(=C2)C3=CC4=C(C=C3)OCO4 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +56640146 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=CC(=CC(=C1OC)C2=CC3=C(C=C2)C=C(C=C3)NS(=O)(=O)C)N4C=CC(=O)NC4=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nonnucleoside hepatitis C virus polymerase inhibitor. +Option B: It is a hepatitis C virus nonstructural protein 5A inhibitor. +Option C: It is a hepatitis C protease inhibitor. +Option D: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. +" A +440869 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC2=C(NC(=O)NC2=O)N(C1=O)C[C@@H]([C@@H]([C@@H](CO)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an ATP synthase inhibitor. +Option B: It is an EC 2.5.1.9 (riboflavin synthase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" B +119054 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [C@@H]1([C@@H]([C@H]([C@H]2[C@@H]([C@@H]1O)O2)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.4.3.22 (diamine oxidase) inhibitor and an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +Option B: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor and an EC 3.1.1.3 (triacylglycerol lipase) inhibitor. +Option C: It is an EC 3.4.21.37 (leukocyte elastase) inhibitor and an EC 3.4.21.64 (peptidase K) inhibitor. +Option D: It is an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor and an EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor. +" D +11363812 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CCC3=C([C@@]1(CC[C@@H]2[C@@H](CC[C@@H](C(C)(C)O)O)C(=O)O)C)CC[C@@H]4[C@@]3(CCC(=O)C4(C)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor and a cyclooxygenase 2 inhibitor. +" D +2333 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)Br)O)Br +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of the tyrosine catabolism. +Option B: It is an inhibitor of cellular mitosis. +Option C: It is an inhibitor of neuronal activity. +Option D: It is an inhibitor of CYP2C9. +" D +1051 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +Option C: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option D: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +" C +6505803 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)/C)OC)OC(=O)N)\\C)C)O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a Hsp90 inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is a heat shock protein 90 (Hsp90) inhibitor. +Option D: It is a heat shock protein (HSP) 90 inhibitor. +" C +11485574 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CC(=O)C1=C(C=C(C=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 1 inhibitor. +Option C: It is a lipoxygenase inhibitor. +Option D: It is a cyclooxygenase inhibitor. +" C +11212172 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C=C1C(F)(F)F)N(N=C2/C=C/C(=O)O)CC3=C(C=C(C=C3)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a thrombin inhibitor. +Option B: It is a Hsp90 inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a P450 inhibitor. +" B +10390162 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)CCl)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCC(=O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.21.37 (leukocyte elastase) inhibitor and an EC 3.4.21.64 (peptidase K) inhibitor. +Option B: It is an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. +Option C: It is an EC 3.4.22.52 (calpain-1) inhibitor and an EC 3.4.22.53 (calpain-2) inhibitor. +Option D: It is an EC 3.4.22.53 (calpain-2) inhibitor. +" A +68047 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=N)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is a nitric oxide synthase inhibitor. +Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option D: It is a nitrification inhibitor. +" C +57401109 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC2=CC(=C3C(=C2)OC(=C(C3=O)O[C@H]4[C@@H]([C@H]([C@H](CO4)O)O)O)C5=CC=C(C=C5)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor. +Option B: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option C: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor. +Option D: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +" B +442665 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)C2=C3C(=C(C(=C2O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)C(=O)C=C(O3)C5=CC=C(C=C5)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" A +73607 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC2=C(C(=O)C[C@H](O2)C3=CC=C(C=C3)O)C(=C1)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase (AChE) inhibitor. +Option B: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +171489 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCC1=C(C(=O)C=C(C1=O)OC)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a hepatitis C protease inhibitor. +Option B: It is a nonnucleoside hepatitis C virus polymerase inhibitor. +Option C: It is a hepatitis C virus nonstructural protein 5A inhibitor. +Option D: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. +" A +1548887 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC\\1=C(C2=C(/C1=C\\C3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option B: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +" B +6279 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]2[C@H](CC[C@]3([C@H]2CC[C@@]3(C(=O)C)OC(=O)C)C)[C@@]4(C1=CC(=O)CC4)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an antioxidant. +Option B: It is an inhibitor of bacterial growth. +Option C: It is an inhibitor of unwanted bacteria. +Option D: It is an inhibitor of cellular mitosis. +" A +31645 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an acetylcholinesterase (AChE) inhibitor. +" C +5284649 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=COC3=CC(=C(C=C3C2=O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase inhibitor. +Option B: It is a tyrosinase inhibitor. +Option C: It is a tyrosine kinase receptor inhibitor. +Option D: It is a tyrosine-kinase inhibitor. +" B +175967 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option B: It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor. +Option C: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option D: It is an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor. +" B +667550 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase 1 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor. +" A +11205153 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an acetolactate synthase inhibitor. +Option C: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +Option D: It is an ATP synthase inhibitor. +" B +46173712 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OC[C@@H]4[C@H]([C@H]([C@H](O4)NC(=NCCC[C@@H](C(=O)O)N)N)O)O)O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a prolyl oligopeptidase inhibitor. +Option B: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor. +Option C: It is a metalloendopeptidase inhibitor. +Option D: It is an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. +" A +5281804 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=C2C(=C1)OC=C(C2=O)C3=CC=C(C=C3)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor. +Option B: It is an EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor. +Option C: It is a 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor. +Option D: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. +" C +2915 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CSSCCN)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a protein-glutamine gamma-glutamyltransferase inhibitor. +Option B: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +Option C: It is a gamma-secretase inhibitor. +Option D: It is a cystathionine gamma-synthase inhibitor. +" A +11534420 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=C(C(=C2O)C1)NCC=C)O)/C)OC)OC(=O)N)\\C)C)O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a DNA synthesis inhibitor. +Option B: It is a P450 inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a Hsp90 inhibitor. +" D +53476539 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]([C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)NP(=O)(OCCCN)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCSC)NC=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an ATP synthase inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an aspartate--tRNA ligase inhibitor. +" D +546 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)O)P(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option B: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option C: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +Option D: It is an EC 3.5.1.5 (urease) inhibitor. +" A +2746 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a histone deacetylase inhibitor. +Option B: It is an oral histone deacetylase inhibitor and antineoplastic agent. +Option C: It is an EC 3.5.1.98 (histone deacetylase) inhibitor. +Option D: It is an inhibitor of histone deacetylase (HDAC). +" C +9912721 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC\\1=C(C2=C(/C1=C\\C3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)OCCCCO[N+](=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option B: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +" A +3017 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)OC1=NC(=NC(=C1)C)C(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" D +38081 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC=C1NC2=C(C=CC=N2)C(=O)O)C(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option C: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option D: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +" C +92434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetolactate synthase inhibitor. +Option B: It is an ATP synthase inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +" D +454202 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCOC(=O)[C@@]1(C[C@H]2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)[C@@]1(O2)C)CNC6=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +Option B: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option D: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. +" A +9500 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=NC=C1C(=O)N)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor. +Option B: It is an EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor. +Option C: It is an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor. +Option D: It is an EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor. +" D +446987 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H](O1)P(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a protein-glutamine gamma-glutamyltransferase inhibitor. +Option B: It is an EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor. +Option C: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. +Option D: It acts as a NAD(+) ADP-ribosyltransferase inhibitor. +" B +5365371 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCC/C=C\\CCCCCCCCCCCC(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +5311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a histone deacetylase inhibitor. +Option B: It is an EC 3.5.1.98 (histone deacetylase) inhibitor. +Option C: It is an inhibitor of histone deacetylase (HDAC). +Option D: It is an oral histone deacetylase inhibitor and antineoplastic agent. +" B +51041756 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC/C(=C/CC1=C2C(=C(C=C1O)O)C(=O)C[C@H](O2)C3=CC(=CC(=C3)O)O)/C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protease inhibitor. +Option B: It is a leukocyte elastase inhibitor. +Option C: It is a breast cancer resistance protein inhibitor. +Option D: It is a cysteine protease inhibitor. +" C +119104 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OC1=CC=C(C=C1)[C@H](C=C)OC(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a kinase inhibitor. +Option B: It is a NF-kappaB inhibitor. +Option C: It is a potent protein kinase C inhibitor. +Option D: It is a mitogen-activated protein kinase inhibitor. +" B +5283454 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCC/C=C\\CCCCCCCC(=O)NCCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option B: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 3.5.1.4 (amidase) inhibitor. +" A +3082 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)CSP(=S)(OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +60490 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective 5-lipoxygenase inhibitor. +Option B: It is a cyclooxygenase inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor. +Option D: It is a lipoxygenase inhibitor. +" A +60490 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an arachidonate 5-lipoxygenase inhibitor. +Option B: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option C: It is an arachidonate 12-lipoxygenase inhibitor. +Option D: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +" B +3278 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)O)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is a glutathione S-transferase (EC 2.5.1.18) inhibitor. +Option C: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option D: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +" B +54960 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +Option C: It is an ATP synthase inhibitor. +Option D: It is an acetolactate synthase inhibitor. +" B +4944 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC1=CC=CC=C1OC(=O)NC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +676454 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)NC(=S)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option C: It is an EC 1.14.14.14 (aromatase) inhibitor. +Option D: It is an EC 4.2.1.1 (carbonic anhydrase) inhibitor. +" B +6918078 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" C +91619 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CP(=O)(CC[C@@H](C(=O)O)N)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 integrase inhibitor. +Option B: It is a protease inhibitor. +Option C: It is a HIV-1 protease inhibitor. +Option D: It is a glutamine synthetase inhibitor. +" D +89034 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=N)(=O)CC[C@@H](C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option C: It is an EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor. +Option D: It is an EC 3.5.1.5 (urease) inhibitor. +" C +67114 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C1=CC=C(C=C1)C=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +Option B: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option C: It is an aldehyde dehydrogenase (NAD(+)) inhibitor. +Option D: It is an aldehyde dehydrogenase 1a2 (ALDH1a2) inhibitor. +" B +439771 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@H](C(=O)O)N)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a serine C-palmitoyltransferase inhibitor. +Option B: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +Option C: It is an EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor. +Option D: It is an EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor. +" C +23677829 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-].O.O.[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option D: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +" C +16759173 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA). +Option B: It is a specific, reversible inhibitor of monoamine oxidase A. +Option C: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +Option D: It is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). +" D +181817 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)[C@H]1C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase 1 inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor and a cyclooxygenase 2 inhibitor. +" B +1549008 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +Option B: It is an EC 1.14.13.132 (squalene monooxygenase) inhibitor. +Option C: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option D: It is an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. +" B +39836 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[C@H](CCCN=C(N)N[N+](=O)[O-])N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitric oxide synthase inhibitor. +Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a nitrification inhibitor. +" B +23665584 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\\C)/CCC(=O)[O-])O.[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.1.1.205 (IMP dehydrogenase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option D: It is an EC 3.5.1.5 (urease) inhibitor. +" A +10250145 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C2=C(C3=C(C=C(C=C3)O)OC2=O)O[C@]1(C)CCC/C(=C\\C(=O)C=C(C)C)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is a nitrification inhibitor. +Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option D: It is a nitric oxide synthase inhibitor. +" C +441350 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@](CC1=CC=C(C=C1)O)(C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option B: It is an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. +Option C: It is an EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor. +Option D: It is an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +" D +51556 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)NC(=O)C1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a reversible monoamine oxidase inhibitor. +Option B: It is a monoamine oxidase inhibitor. +Option C: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. +Option D: It acts as a protoporphyrinogen oxidase inhibitor. +" C +10340706 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C2=C(C3=C(C=C(C=C3)O)OC2=O)O[C@]1(C)CCC/C(=C/C(=O)C=C(C)C)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is a nitric oxide synthase inhibitor. +Option C: It is a nitrification inhibitor. +Option D: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +" D +11258152 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C(CC1=C(C(=C(C=C1O)OC)C(=O)/C=C/C2=CC=C(C=C2)O)O)O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is a nitrification inhibitor. +Option D: It is a nitric oxide synthase inhibitor. +" A +10317069 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=C)C(CC1=C(C(=C(C=C1O)OC)C(=O)/C=C/C2=CC=C(C=C2)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitric oxide synthase inhibitor. +Option B: It is a nitrification inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +" D +173685 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H](C=CC=C1C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor. +Option B: It is an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor. +Option C: It is an EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor. +Option D: It is an EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor. +" B +115355 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)C(C(=O)C1)C(=O)C2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor. +Option B: It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor. +Option C: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option D: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +" A +54726191 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is a HIV-1 integrase inhibitor. +Option C: It is an HIV protease inhibitor. +Option D: It is a HIV-1 reverse transcriptase inhibitor. +" B +67678 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an aldehyde dehydrogenase (NAD(+)) inhibitor. +Option B: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option C: It is an EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor. +Option D: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +" D +2601 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C1=CC=C(C=C1)N=NC2=CC(=C(C=C2)O)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor. +Option B: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. +Option C: It is an EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor. +Option D: It is an EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor. +" D +442614 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=C2C(=C1O)[C@]3(C(=CC(=C(C3=O)C(=O)C)O)O2)C)C(=O)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option B: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option C: It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor. +Option D: It is an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor. +" D +3295 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC1=CC2=C(C=C1)N=C(S2)S(=O)(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is an EC 4.2.1.1 (carbonic anhydrase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor. +" B +135193 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[C@H](CCCN=C(N)N[N+](=O)[O-])N.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitrification inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option D: It is a nitric oxide synthase inhibitor. +" C +11957547 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC[C@@H]([C@@H](C)O)N1C=NC2=C(N=CN=C21)N.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor. +Option B: It is an EC 3.5.1.4 (amidase) inhibitor. +Option C: It is an EC 3.1.1.4 (phospholipase A2) inhibitor. +Option D: It is an EC 3.5.1.23 (ceramidase) inhibitor. +" A +10247837 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC[C@]1([C@H](CC2=C(O1)C(=CC(=C2)C(=O)O)CC=C(C)C)O)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cysteine protease inhibitor. +Option B: It is a gamma-secretase inhibitor. +Option C: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +Option D: It is a cystathionine gamma-synthase inhibitor. +" C +61672 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [O-][V](=O)([O-])[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option B: It is an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor and an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option C: It is an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor. +Option D: It is an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor. +" A +6857538 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@H](C(=O)O)N)SSC[C@H](C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor. +Option B: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +Option C: It is an aldehyde dehydrogenase (NAD(+)) inhibitor. +Option D: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +" B +67537 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)C(=O)O)I=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor. +Option B: It is an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor. +" A +522251 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C=C1C)Cl)OC(=O)NC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" C +122340 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor. +Option B: It is an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor. +Option C: It is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. +Option D: It is an EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor. +" D +119435 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)O)OC1=C(C=C(C=C1)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 3.5.1.4 (amidase) inhibitor. +Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor. +" B +76617 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCC1=CC(=CC(=C1)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 1.1.5.3 (glycerol-3-phosphate dehydrogenase) inhibitor. +Option D: It is an EC 5.3.1.1 (triose-phosphate isomerase) inhibitor. +" C +9570991 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)/N=C(/C1=C(C=CC(=C1)OC2=C(C=C(C=C2)C(F)(F)F)Cl)[N+](=O)[O-])\\[O-].[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. +Option B: It acts as a protoporphyrinogen oxidase inhibitor. +Option C: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +Option D: It is a reversible monoamine oxidase inhibitor. +" A +9978057 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C2=C(C3=C(C=C(C=C3)O)OC2=O)O[C@]1(C)CCC/C(=C\\C(=O)C=C(C)C)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitric oxide synthase inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is a nitrification inhibitor. +Option D: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +" D +137333845 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CP(=O)(CC[C@@H](C(=O)[O-])[NH3+])[O-].[NH4+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor. +Option B: It is an EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" A +12315315 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)O[P@@](=O)(C)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase (AChE) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 2.5.1.18 (glutathione transferase) inhibitor. +" A +26964 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as an aromatic-L-amino-acid decarboxylase inhibitor. +Option B: It acts as a L-amino-acid oxidase inhibitor. +Option C: It acts as an adenosine deaminase inhibitor. +Option D: It is an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. +" D +476994 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)C2=C3C4=CC(=C(C=C4C=CN3C5=C2C6=CC(=C(C=C6OC5=O)OS(=O)(=O)O)OC)OC)OC)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is a HIV-1 reverse transcriptase inhibitor. +Option C: It is an HIV protease inhibitor. +Option D: It is a HIV-1 integrase inhibitor. +" D +6099 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.4.3.4 (monoamine oxidase) inhibitor. +Option B: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. +Option C: It is an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. +Option D: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor. +" A +6451164 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option B: It is a HIV-1 reverse transcriptase inhibitor and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option C: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option D: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +" B +23663400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It acts as a suicide inhibitor of bacterial beta-lactamase enzymes. +Option C: It is a protease inhibitor. +Option D: It is a beta-lactamase inhibitor. +" D +133145 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=CC(=C1)CCC(=O)CCCCC2=CC=CC=C2)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 1 inhibitor and a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase 1 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +" A +4705 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an IP3 receptor antagonist. +Option B: It is a selective serotonin reuptake inhibitor (SSRI). +Option C: It is a selective serotonin receptor antagonist. +Option D: It is an epidermal growth factor receptor antagonist. +" D +68081 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCOC1=C2C=CC(=O)OC2=CC3=C1C=CO3)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" B +24341 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: OCl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 2.5.1.18 (glutathione transferase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +135410875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. +Option B: It inhibits the enzyme dihydrofolate reductase. +Option C: It is an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor. +Option D: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. +" D +2733505 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=NCCCC[C@@H](C(=O)O)N)N.Cl.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option B: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option C: It is an EC 1.14.14.14 (aromatase) inhibitor. +Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +" A +9922008 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCC/C=C/C1=CC2=C(C=C1)OCO2 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option B: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option C: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. +Option D: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor. +" B +5484172 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)O)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitor. +Option B: It is a pyruvate carboxylase inhibitor. +Option C: It is an EC 6.4.1.1 (pyruvate carboxylase) inhibitor. +Option D: It acts as an acetyl-CoA carboxylase inhibitor. +" A +86289348 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option B: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +Option C: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option D: It is an EC 3.5.1.5 (urease) inhibitor. +" A +3541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNCC=CC3=CC=C(C=C3)Br +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option B: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. +Option C: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option D: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +" D +2136 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase 1 inhibitor and a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" A +10485148 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C(OC4=CC(=CC(=C4C3=O)O)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)C6=CC=C(C=C6)O)CO)O)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor. +Option B: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option C: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor. +Option D: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +" A +446845 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase inhibitor and a Wnt signalling inhibitor. +Option B: It is a mitochondrial cytochrome-bc1 complex inhibitor. +Option C: It is a lipoxygenase inhibitor and a platelet aggregation inhibitor. +Option D: It is a mitochondrial cytochrome-bc1 complex inhibitor and a quinone outside inhibitor. +" D +5965 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C.[Br-].[Br-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor and a cholinesterase inhibitor. +Option B: It is an inhibitor of acetylcholinesterase and pseudocholinesterase. +Option C: It is an acetylcholinesterase (AChE) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" B +6083 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor and an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option B: It is an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor. +Option C: It is an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option D: It is an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor. +" A +10992937 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C2=C(C3=C(C=C(C=C3)O)OC2=O)O[C@]1(C)CC/C=C(\\C)/CC(=O)C=C(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option B: It is a nitric oxide synthase inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a nitrification inhibitor. +" A +25154714 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C(N5)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a hepatitis C virus nonstructural protein 5A inhibitor. +Option B: It is a nonnucleoside hepatitis C virus polymerase inhibitor. +Option C: It is a nonstructural protein 5A inhibitor. +Option D: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. +" C +70269 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NNC(=O)NC1=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor. +Option B: It is an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor. +Option C: It is an EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor. +Option D: It is an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor. +" C +23665411 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-].[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option B: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +" B +5287547 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2C(=NC=N1)N=CN2 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor. +Option B: It is an EC 3.1.1.4 (phospholipase A2) inhibitor. +Option C: It is a phosphoinositide phospholipase C inhibitor. +Option D: It is an EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor. +" D +5282433 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCOC1=CC=CC=C1/C(=C\\SC)/N2C=CN=C2 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option B: It is a sterol 14alpha-demethylase inhibitor. +Option C: It is an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. +Option D: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. +" C +9321 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: NN +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor. +Option B: It is an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor. +Option C: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +Option D: It is an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. +" A +3496 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)O)NCP(=O)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor. +Option B: It is an EC 2.5.1.19 (3-phosphoshikimate 1-carboxyvinyltransferase) inhibitor. +Option C: It is an EC 2.6.1.40 [(R)-3-amino-2-methylpropionate--pyruvate transaminase] inhibitor. +Option D: It is an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor. +" B +11361458 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C2=C(C3=C(C=C(C=C3)O)OC2=O)O[C@]1(C)CC/C=C(\\C)/CC(=O)C=C(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option C: It is a nitrification inhibitor. +Option D: It is a nitric oxide synthase inhibitor. +" B +10383781 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCCC(C)(C1CC2=C(O1)C(=CC(=C2)C(=O)O)CC=C(C)C)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a gamma-secretase inhibitor. +Option B: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +Option C: It is a cystathionine gamma-synthase inhibitor. +Option D: It is a leukocyte elastase inhibitor. +" B +23665591 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]2N(C1=O)[C@H](/C(=C/CO)/O2)C(=O)[O-].[K+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a suicide inhibitor of bacterial beta-lactamase enzymes. +Option B: It is a protease inhibitor. +Option C: It is a HIV-1 protease inhibitor. +Option D: It is a beta-lactamase inhibitor. +" A +23665591 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]2N(C1=O)[C@H](/C(=C/CO)/O2)C(=O)[O-].[K+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is a beta-lactamase inhibitor. +Option C: It acts as a suicide inhibitor of bacterial beta-lactamase enzymes. +Option D: It is a protease inhibitor. +" B +10439877 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCOC(=O)/N=C(\\C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)/N.CS(=O)(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 3.4.21.5 (thrombin) inhibitor. +Option D: It is an EC 3.5.1.5 (urease) inhibitor. +" C +20401 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC2=C(C=C1)NC(=C2)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitor. +Option B: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option C: It is an EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor. +Option D: It is an EC 1.4.1.3 (glutamate dehydrogenase [NAD(P)(+)] inhibitor). +" C +10050581 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC/C(=C/CC1=C(C(=C2C(=C1O)C=CC(O2)(C)C)C(=O)/C=C/C3=CC=C(C=C3)O)O)/C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +" C +12665 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCNC(=O)C1 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an aldehyde dehydrogenase (NAD(+)) inhibitor. +Option B: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +Option C: It is an EC 1.2.1.88 (L-glutamate gamma-semialdehyde dehydrogenase) inhibitor. +Option D: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +" C +10409177 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C2=C(C3=C(C=C(C=C3)OC)OC2=O)O[C@]1(C)CC/C=C(\\C)/CC4=CC(=CO4)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is a nitrification inhibitor. +Option C: It is a nitric oxide synthase inhibitor. +Option D: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +" D +10427384 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CC/C=C(\\C)/C1CC2=C(O1)C(=CC(=C2)C(=O)O)CC=C(C)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +Option B: It is a cysteine protease inhibitor. +Option C: It is a cystathionine gamma-synthase inhibitor. +Option D: It is a gamma-secretase inhibitor. +" A +23668320 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CC[C@@H](C4)OS(=O)(=O)[O-])C.[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor. +Option B: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor. +Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option D: It is a pyruvate kinase inhibitor. +" B +71080 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. +Option B: It is an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor. +" B +24812732 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=C/C(=O)O)\\C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an ATP synthase inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor. +" A +5862 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H](C(=O)O)N)S +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option C: It is an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. +Option D: It is an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor. +" C +5509 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option D: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +" C +46216805 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]1(C=CC2=C(O1)C=CC(=C2)O)CO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option C: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option D: It is an EC 1.14.14.14 (aromatase) inhibitor. +" B +2327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a sterol biosynthesis inhibitor. +Option B: It is a carotenoid biosynthesis inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor. +Option D: It is a DOPA decarboxylase inhibitor. +" D +198737 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1=CC=C(C=C1)C(=C2C=CC(=N)C=C2)C3=CC=C(C=C3)N(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. +Option B: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. +Option C: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor. +Option D: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor. +" B +6435927 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]([C@@H](O)C)[C@@H]1O[C@H]1C[C@@H]2[C@H]([C@H]([C@@H](OC2)C/C(=C/C(=O)OCCCCCCCCC(=O)[O-])/C)O)O.C[C@@H]([C@@H](O)C)[C@@H]1O[C@H]1C[C@@H]2[C@H]([C@H]([C@@H](OC2)C/C(=C/C(=O)OCCCCCCCCC(=O)[O-])/C)O)O.[Ca+2] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a DNA synthesis inhibitor. +Option B: It is a mitotic inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a potent inhibitor. +" C +135460966 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)OP(=O)(O)O)N=C(NC2=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.27.3 (ribonuclease T1) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor. +" A +1548972 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)N1C2=CC=CC=C2C(=C1/C=C/[C@@H](C[C@@H](CC(=O)O)O)O)C3=CC=C(C=C3)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a glutamine synthetase inhibitor. +Option B: It is a 5-alpha reductase inhibitor. +Option C: It is a ribonucleotide reductase inhibitor. +Option D: It is an HMG-CoA reductase inhibitor. +" D +149784 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC[C@@H]([C@@H](C)O)N1C=NC2=C(N=CN=C21)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option B: It is an EC 3.5.4.4 (adenosine deaminase) inhibitor. +Option C: It is an EC 3.5.1.4 (amidase) inhibitor. +Option D: It is an EC 3.5.1.5 (urease) inhibitor. +" B +5388906 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC[C@@](C1=CC=CC2=CC=CC=C21)([C@H](C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option C: It is an ATP synthase inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" C +9548904 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H](O[C@H]1C2=CC(=C(C=C2)O)OC)C3=CC(=C(C=C3)OC)OC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is a nitric oxide synthase inhibitor. +Option D: It is a nitrification inhibitor. +" A +1433 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=NCC1=CC=CC(=C1)CN)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option B: It is an EC 1.14.14.14 (aromatase) inhibitor. +Option C: It is a nitric oxide synthase inhibitor. +Option D: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +" D +9864 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(#N)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option B: It is an aldehyde dehydrogenase (NAD(+)) inhibitor. +Option C: It is an aldehyde dehydrogenase 1a2 (ALDH1a2) inhibitor. +Option D: It is an EC 1.2.1.12 (aspartate-semialdehyde dehydrogenase) inhibitor. +" A +5280373 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a specific tyrosine kinase receptor inhibitor. +Option B: It is a tyrosine kinase inhibitor. +Option C: It is a selective tyrosine kinase receptor inhibitor. +Option D: It is a tyrosine kinase receptor inhibitor. +" B +25102847 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a specific tyrosine kinase receptor inhibitor. +Option B: It is a tyrosine kinase inhibitor. +Option C: It is a selective tyrosine kinase receptor inhibitor. +Option D: It is a tyrosine kinase receptor inhibitor. +" B +2901 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(C1)(C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. +Option B: It acts as a methionine adenosyltransferase inhibitor. +Option C: It acts as a NAD(+) ADP-ribosyltransferase inhibitor. +Option D: It is an EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor. +" B +118796904 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: O.O.O.O.O.Cl[Cu]Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.166 (heparanase) inhibitor. +Option B: It is an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor. +Option C: It is a cholestenol Delta-isomerase inhibitor. +Option D: It is an EC 3.4.21.5 (thrombin) inhibitor. +" C +46216142 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an HIV protease inhibitor. +Option B: It is a HIV-1 reverse transcriptase inhibitor. +Option C: It is a HIV-1 integrase inhibitor. +Option D: It is a HIV-1 protease inhibitor. +" C +9084 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)[O-])C(=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a mitochondrial respiratory-chain inhibitor. +Option B: It is a thrombin inhibitor. +Option C: It is a Hsp90 inhibitor. +Option D: It is a P450 inhibitor. +" A +168091 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C#CC[C@@H](C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as an adenosine deaminase inhibitor. +Option B: It is an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. +Option C: It acts as an aromatic-L-amino-acid decarboxylase inhibitor. +Option D: It acts as a L-amino-acid oxidase inhibitor. +" D +54792409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)O.C1CCC(CC1)C2=CC3=C(C=C2)N4CCNC5C4=C3CCC5 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +Option B: It is a monoamine oxidase inhibitor. +Option C: It is a specific, reversible inhibitor of monoamine oxidase A. +Option D: It is a reversible monoamine oxidase inhibitor. +" B +38101 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN.O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as an adenosine deaminase inhibitor. +Option B: It is an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. +Option C: It acts as an aromatic-L-amino-acid decarboxylase inhibitor. +Option D: It acts as a L-amino-acid oxidase inhibitor. +" C +196876 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)CSC1=[N+](C=CN1C)C.[Cl-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a gamma-secretase inhibitor. +Option B: It is a cystathionine gamma-synthase inhibitor. +Option C: It acts as a protein-glutamine gamma-glutamyltransferase inhibitor. +Option D: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +" C +5362119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option B: It is an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. +Option C: It is an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. +Option D: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. +" C +5237 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)O)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 4.2.1.3 (aconitate hydratase) inhibitor. +" D +11005 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.1 (carboxylesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +123831 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C(=NCCC[C@@H](C(=O)O)N)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitrification inhibitor. +Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option C: It is a nitric oxide synthase inhibitor. +Option D: It is a protein synthesis inhibitor. +" B +13836 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[N+](C)(C)CCCl.[Cl-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a sterol biosynthesis inhibitor. +Option B: It is a carotenoid biosynthesis inhibitor. +Option C: It is a gibberellin biosynthesis inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor. +" C +44558863 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [H+].C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F.[Cl-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. +Option B: It is an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor. +Option C: It is an EC 1.14.14.14 (aromatase) inhibitor. +Option D: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. +" B +156126 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C[C@@H](C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +Option B: It is an EC 4.4.1.14 (1-aminocyclopropane-1-carboxylate synthase) inhibitor. +Option C: It is an EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor. +Option D: It is an EC 4.3.1.3 (histidine ammonia-lyase) inhibitor. +" B +151166 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C=C1)NC2=C(C=CC=C2Cl)F)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" B +11329481 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. +Option B: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. +Option C: It inhibits the enzyme dihydrofolate reductase. +Option D: It is an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor. +" B +4679 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of the NA(+)-K(+)-exchanging ATPase. +Option B: It is an EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor. +Option C: It is an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. +Option D: It is an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor. +" D +18752 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)NS(=O)(=O)C1=CC=C(C=C1)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.4 (amidase) inhibitor. +Option B: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. +" D +3008318 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCC(=O)N[C@H](CN1CCOCC1)[C@@H](C2=CC=CC=C2)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor. +Option B: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +Option C: It is an EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor. +Option D: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. +" A +5320053 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.5 (urease) inhibitor. +Option B: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option C: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +Option D: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +" D +5282432 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCOC1=CC=CC=C1/C(=C\\SC)/N2C=CN=C2.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. +Option B: It is a sterol 14alpha-demethylase inhibitor. +Option C: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option D: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. +" A +70697791 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C[C@@H]1OC)[C@@H]2[C@H](C(=C)C(=O)O2)CCC(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitrification inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option D: It is a nitric oxide synthase inhibitor. +" C +184900 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)C1C(=O)CC(CC1=O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a carotenoid biosynthesis inhibitor. +Option B: It is a sterol biosynthesis inhibitor. +Option C: It is a gibberellin biosynthesis inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor. +" C +369401 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C2=C(C3=CC=CC=C3NC1=O)NC4=CC=CC=C24 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclin-dependent kinase inhibitor. +Option B: It is a cyclin dependent kinase inhibitor. +Option C: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option D: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +" C +54676254 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=C(C2=C(C=C(C=C2)O)OC1=O)O)/C(=C/C/C=C(\\C)/CC(=O)C=C(C)C)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option C: It is a nitric oxide synthase inhibitor. +Option D: It is a nitrification inhibitor. +" B +5282481 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +Option B: It is an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor. +Option C: It is an EC 1.14.13.132 (squalene monooxygenase) inhibitor. +Option D: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +" C +4037 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)O)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an arachidonate 12-lipoxygenase inhibitor. +Option B: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option C: It is an arachidonate 5-lipoxygenase inhibitor. +Option D: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +" B +11693711 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N(N1)C)C(=O)C2=C(C=C(C=C2)C(F)(F)F)S(=O)(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor. +Option B: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option C: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option D: It is an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor. +" D +11601663 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC=CC(=C1OC)/C=C/C2=CC(=CC(=C2)OC)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option B: It is a nitrification inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a nitric oxide synthase inhibitor. +" A +11711114 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option B: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +" A +2733490 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNCC=CC3=CC=C(C=C3)Br.Cl.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option B: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. +Option C: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +Option D: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +" C +5362123 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. +Option B: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. +Option C: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option D: It is an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. +" D +183137 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=C(C(=C1O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C)O[C@@H](CC2=O)C4=C(C=CC(=C4)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor. +Option B: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option C: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. +Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +" D +11685945 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=C(C(=C2O)C1)NCC=C)O)/C)OC)OC(=O)N)\\C)C)O)OC.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is a thrombin inhibitor. +Option C: It is a P450 inhibitor. +Option D: It is a Hsp90 inhibitor. +" D +688461 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C2C(=CC=C1)C3=C(N2)[C@](OCC3)(CC)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option D: It is a cyclooxygenase inhibitor. +" B +24014 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: Cl[Cu]Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.166 (heparanase) inhibitor. +Option B: It is a cholestenol Delta-isomerase inhibitor. +Option C: It is an EC 3.4.21.5 (thrombin) inhibitor. +Option D: It is an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor. +" D +16004 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=NC(=C1)Cl)C(Cl)(Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitrification inhibitor. +Option B: It acts as a DNA synthesis inhibitor. +Option C: It is a competitive inhibitor. +Option D: It is a protein synthesis inhibitor. +" A +5324512 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C2=C(C3=C(C=C(C=C3)O)OC2=O)O[C@]1(C)CCC/C(=C/C(=O)C=C(C)C)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitrification inhibitor. +Option B: It is a nitric oxide synthase inhibitor. +Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option D: It is a protein synthesis inhibitor. +" C +1639 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NNC(=N1)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an EC 2.5.1.9 (riboflavin synthase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor. +Option D: It is a carotenoid biosynthesis inhibitor. +" C +10047038 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C2=C(C3=C(C=C(C=C3)OC)OC2=O)O[C@]1(C)CC/C=C(\\C)/CC4=CC(=CO4)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option C: It is a nitric oxide synthase inhibitor. +Option D: It is a nitrification inhibitor. +" B +13389335 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.4 (amidase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option D: It is an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. +" D +44433697 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CO)NC(=O)OC(C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a 3C-like protease inhibitor. +Option B: It is a HIV-1 protease inhibitor. +Option C: It is a cysteine protease inhibitor. +Option D: It is a protease inhibitor. +" A +44433697 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)/C=C/[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CO)NC(=O)OC(C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. +Option B: It is an EC 3.4.22.53 (calpain-2) inhibitor. +Option C: It is an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor. +Option D: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor. +" C +216210 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.4.3.22 (diamine oxidase) inhibitor and an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor. +Option B: It is an EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor and an EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor. +Option C: It is an EC 3.4.21.5 (thrombin) inhibitor and an EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor. +Option D: It is an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor and an EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor. +" C +21157 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCS(=N)(=O)CCC(C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" C +2471 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. +Option B: It is an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor. +Option C: It is an EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor. +Option D: It is an inhibitor of the NA(+)-K(+)-exchanging ATPase. +" C +11558520 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=CC(=C1)O)/C=C/C2=C(C(=C(C=C2)O)OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a protein synthesis inhibitor. +Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option C: It is a nitrification inhibitor. +Option D: It is a nitric oxide synthase inhibitor. +" B +43234 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. +Option B: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option C: It is an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. +Option D: It is a sterol 14alpha-demethylase inhibitor. +" C +91762 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)O)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +Option B: It is an acetolactate synthase inhibitor. +Option C: It is an ATP synthase inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" A +104818 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)(N)NS(=O)(=O)NC(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an acetolactate synthase inhibitor. +Option C: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +Option D: It is an ATP synthase inhibitor. +" C +132472359 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)/C(=N/P(=O)(C)F)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +62956 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(CC1)[C@@H]2C[C@H](N(C2)C(=O)CP(=O)(CCCCC3=CC=CC=C3)O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin converting enzyme (ACE) inhibitor. +Option B: It is an angiotensin II receptor blocker. +Option C: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option D: It is an angiotensin-converting enzyme (ACE) inhibitor. +" A +3039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(OC)OC=C(Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor and a cholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" D +108152 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@]12[C@](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CN(C6=O)C)(C(=O)OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a potent protein kinase C inhibitor. +Option B: It is a Ca(2+)/calmodulin-dependent protein kinase inhibitor. +Option C: It is a cGMP-dependent protein kinase inhibitor. +Option D: It is a mitogen-activated protein kinase inhibitor. +" C +60750 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a ribonucleotide reductase inhibitor. +Option B: It is a protease inhibitor. +Option C: It is a 5-alpha reductase inhibitor. +Option D: It is a glutamine synthetase inhibitor. +" A +1781 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCC#CCC#CCC#CCCCC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option B: It is an arachidonate 12-lipoxygenase inhibitor. +Option C: It is an arachidonate 5-lipoxygenase inhibitor. +Option D: It is an arachidonate 5-lipoxygenase inhibitor and a cyclooxygenase 2 inhibitor. +" B +3080614 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)O)NC(=O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an alpha-ketoglutarate dependent (EC 1.14.11.*) enzymes inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 4.2.1.1 (carbonic anhydrase) inhibitor. +Option D: It is an alpha-amylase inhibitor. +" A +136273333 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](C(C)C)C(=O)OC)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)OC(C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cystathionine gamma-synthase inhibitor. +Option B: It acts as a protein-glutamine gamma-glutamyltransferase inhibitor. +Option C: It is an EC 4.4.1.11 (methionine gamma-lyase) inhibitor. +Option D: It is a gamma-secretase inhibitor. +" B +3308 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C2C(=CC=C1)C3=C(N2)C(OCC3)(CC)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclo-oxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor. +Option C: It is a cyclooxygenase inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" A +11522311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C(=C(C=C1)/C=C/C2=CC(=CC(=C2)OC)O)OC)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as a DNA synthesis inhibitor. +Option B: It is a nitric oxide synthase inhibitor. +Option C: It is a nitrification inhibitor. +Option D: It is a protein synthesis inhibitor. +" B +10548 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(OCC)SCC[N+](C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase (AChE) inhibitor. +" A +8400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(C(=O)C2=CC=CC=C2)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is a carboxylesterase inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an EC 3.1.1.1 (carboxylesterase) inhibitor. +" B +637759 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)/C=C/C1=CC=CC=C1 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as an inhibitor of the enzyme phospholipase A2 (EC 3.1.1.4) of insects like diamond back moth. +Option B: It is an EC 3.1.1.4 (phospholipase A2) inhibitor. +Option C: It is an inhibitor of phospholipase A2. +Option D: It is a phospholipase A2 (PLA2) inhibitor. +" A +135398739 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@@H](O[C@@H]1CO)N2C=NC3=C2N=CNC3=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor. +Option B: It is a phosphoinositide phospholipase C inhibitor. +Option C: It is an EC 3.1.1.4 (phospholipase A2) inhibitor. +Option D: It is an EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor. +" D +94830 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C=C(N=C1Cl)Cl)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor. +Option B: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +" A +9576787 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC/C=C/C/C=C/C=C/C=N/NN=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. +Option B: It acts as an aromatic-L-amino-acid decarboxylase inhibitor. +Option C: It acts as a L-amino-acid oxidase inhibitor. +Option D: It is an EC 6.2.1.3 (long-chain-fatty-acid--CoA ligase) inhibitor. +" D +689043 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1/C=C/C(=O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option B: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option C: It is an arachidonate 12-lipoxygenase inhibitor. +Option D: It is an arachidonate 5-lipoxygenase inhibitor. +" B +20039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@@H](O[C@@H]1CO)N2C=NC3=C(N=CN=C32)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.6.1.1 (adenylate cyclase) inhibitor. +Option B: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +" A +5371562 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C\\C(=O)NC)/OP(=O)(OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" C +132887 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](CN[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)O)NC[C@H](CS)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. +Option B: It is an EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor. +Option C: It acts as a NAD(+) ADP-ribosyltransferase inhibitor. +Option D: It is an EC 2.5.1.58 (protein farnesyltransferase) inhibitor. +" D +137333891 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCN(CC3)C(=O)CN(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option B: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option C: It is a cyclin dependent kinase inhibitor. +Option D: It is a cyclin-dependent kinase inhibitor. +" A +5625 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is an HIV protease inhibitor. +Option C: It is a HIV-1 reverse transcriptase inhibitor. +Option D: It is a HIV-1 integrase inhibitor. +" C +75902 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1(=C(NC(=C(C1=O)Cl)F)F)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor. +Option B: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +Option C: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. +Option D: It is an EC 2.5.1.58 (protein farnesyltransferase) inhibitor. +" A +178033 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCSP(=O)(C)OCC(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" A +5353431 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)S(=O)(=O)/C=C/C#N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +Option B: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. +Option C: It is an EC 2.7.11.10 (IkappaB kinase) inhibitor. +Option D: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +" C +11556911 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor. +Option B: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option C: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option D: It is an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor. +" D +5723 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=CC(=C1)C2=NNC(=O)C=C2)OC(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a sterol biosynthesis inhibitor. +Option B: It is a phosphodiesterase IV inhibitor. +Option C: It is a thrombin inhibitor. +Option D: It is a phosphodiesterase inhibitor. +" D +47491 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.11.1.6 (catalase) inhibitor. +Option B: It is an ATP synthase inhibitor. +Option C: It is an acetolactate synthase inhibitor. +Option D: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +" D +3532 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CNCC(=C1)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a competitive inhibitor. +Option B: It is a GABA reuptake inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It acts as a DNA synthesis inhibitor. +" B +4412951 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCC1=C(C2=C(C=C1)C(=O)C3=CC=CC=C3C2=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.4.1.3 (glutamate dehydrogenase [NAD(P)(+)] inhibitor). +Option B: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option C: It is an EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor. +Option D: It is an EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitor. +" A +441300 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a reverse transcriptase inhibitor. +Option B: It is a nucleoside reverse transcriptase inhibitor. +Option C: It is a nucleoside analogue and reverse transcriptase inhibitor. +Option D: It is a HIV-1 reverse transcriptase inhibitor. +" D +3401 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(C2=CC=C(C=C2)F)(C3=CC=CC=C3F)N4C=CN=C4 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor. +Option B: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor. +Option C: It is an EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor. +Option D: It is a sterol 14alpha-demethylase inhibitor. +" C +34359 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)NN +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as an aromatic-L-amino-acid decarboxylase inhibitor. +Option B: It acts as an adenosine deaminase inhibitor. +Option C: It acts as a L-amino-acid oxidase inhibitor. +Option D: It is an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor. +" D +3038 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 4.2.1.1 (carbonic anhydrase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option D: It is an EC 3.5.1.5 (urease) inhibitor. +" A +10547 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(OCC)SCC[N+](C)(C)C.[I-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" C +21803 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=S)(OC)OC1=NC(=C(C=C1Cl)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +6178111 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)N=C(N)/N=C(\\N)/NC1=CC=C(C=C1)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. +Option B: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor. +Option C: It is an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor. +Option D: It inhibits the enzyme dihydrofolate reductase. +" D +6433107 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC(=C(C=C1)NC2=C(C(=CC(=C2F)F)F)F)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +" C +180 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.4 (amidase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" A +4592 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C(N=C(N=C21)NCCO)NCC3=CC=CC=C3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclin-dependent kinase inhibitor. +Option B: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option D: It is a cyclin dependent kinase inhibitor. +" B +91666359 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)[C@@H]([C@H]1[C@@H](C[C@@H]([C@H]1O)C(=O)O)N=C(N)N)NC(=O)C.O.O.O.O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option B: It is an EC 3.5.1.23 (ceramidase) inhibitor. +Option C: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. +Option D: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor. +" C +11507326 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=CC(=C1)O)/C=C/C2=C(C(=CC=C2)O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitric oxide synthase inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +Option D: It is a nitrification inhibitor. +" C +11828024 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OC[C@@]1([C@H](CC[C@]2([C@H]1C[C@@H]([C@@]3([C@@H]2[C@H](C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)OC(=O)C)C)OC(=O)C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It acts as an inhibitor of acyl-CoA:cholesterol acyltransferase. +Option B: It is an EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor. +Option C: It is an acyl-CoA:cholesterol acyltransferase 2 inhibitor. +Option D: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor. +" C +134123139 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)N.[K+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a dihydropteroate synthase inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 2.5.1.15 (dihydropteroate synthase) inhibitor. +Option D: It is an EC 2.5.1.9 (riboflavin synthase) inhibitor. +" A +1967 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)C(=C(C1=O)C)CCCCC#CCCCC#CCO)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an arachidonate 12-lipoxygenase inhibitor. +Option B: It is an arachidonate 5-lipoxygenase inhibitor. +Option C: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +Option D: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +" C +23665728 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)[O-].[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase inhibitor. +Option C: It is a cyclo-oxygenase 2 inhibitor. +Option D: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +" A +159969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CC(C1=C(C(=C(C(=C1O)CC=C(C)C)O)C(=O)C)O)C2=C(C(=C(C(=C2O)CC=C(C)C)OC)C(=O)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +Option B: It is an EC 1.14.14.14 (aromatase) inhibitor. +Option C: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor. +" C +135526609 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N.O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +Option D: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +" C +2581 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. +Option D: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +" C +132472360 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)/C(=N/P(=O)(OC)F)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an acetylcholinesterase inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +" C +5353454 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(/C=C/C1=CC(=CC=C1)OC2=CC=C(C=C2)F)N(C(=O)N)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an arachidonate 12-lipoxygenase inhibitor. +Option B: It is an arachidonate 5-lipoxygenase inhibitor. +Option C: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor. +Option D: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. +" D +6584 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor. +Option B: It is an EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor and an EC 2.7.1.1 (hexokinase) inhibitor. +Option C: It is an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. +Option D: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor. +" A +86416 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C(=O)O)S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor. +Option B: It is an EC 3.5.1.5 (urease) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor. +" A +11476460 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4C[C@@H](OC4=O)COP(=O)(O)O)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a potent inhibitor. +Option B: It acts as a DNA synthesis inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a competitive inhibitor. +" C +18618641 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: O.O.O.[O-]S(=O)(=O)[O-].O=[V+2] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option B: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option C: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. +Option D: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +" D +92389 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)OC2=C(C(=C(C=C2)[N+](=O)[O-])N)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +Option B: It acts as a protoporphyrinogen oxidase inhibitor. +Option C: It is a reversible monoamine oxidase inhibitor. +Option D: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. +" D +8371 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1(=C(C(=O)C(=C(C1=O)Cl)Cl)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor. +Option B: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor. +Option C: It is a pyruvate kinase inhibitor. +Option D: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +" A +8288 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)CC2=CC=CC=C2Cl.[Cl-].[Cl-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" A +10343070 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C(C(=CC(=C1)C2=C(C(=O)C3=C(O2)C=C(C(=C3O)CC=C(C)C)O)O)O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of phospholipase A2. +Option B: It is a phospholipase A2 (PLA2) inhibitor. +Option C: It is a phospholipase A2 inhibitor. +Option D: It is an EC 3.1.1.4 (phospholipase A2) inhibitor. +" D +135398508 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nucleoside reverse transcriptase inhibitor. +Option B: It is a first generation nucleoside analogue and reverse transcriptase inhibitor. +Option C: It is a nucleoside analogue and reverse transcriptase inhibitor. +Option D: It is a reverse transcriptase inhibitor. +" A +135398508 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.7.6 (RNA polymerase) inhibitor. +Option B: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. +Option C: It is an EC 3.5.1.5 (urease) inhibitor. +Option D: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. +" D +5379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor. +Option B: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option C: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option D: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor. +" B +4380 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a specific, reversible inhibitor of monoamine oxidase A. +Option B: It is a monoamine oxidase inhibitor. +Option C: It is a reversible monoamine oxidase inhibitor. +Option D: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +" B +54684141 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C(\\C#N)/C(=O)NC1=CC=C(C=C1)C(F)(F)F)/O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.4.3.4 (monoamine oxidase) inhibitor. +Option B: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option C: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +Option D: It is an EC 1.3.98.1 [dihydroorotate oxidase (fumarate)] inhibitor. +" D +47759 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC(=O)N(C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 2.5.1.18 (glutathione transferase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase (AChE) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +5462501 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)N[C@@H](CCC2=CC=CC=C2)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin converting enzyme (ACE) inhibitor. +Option B: It is an angiotensin-converting enzyme (ACE) inhibitor. +Option C: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option D: It is an angiotensin II receptor blocker. +" B +2484 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=CC=C(C=C1)CN(C)CC2=CC=CC3=CC=CC=C32 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.13.132 (squalene monooxygenase) inhibitor. +Option B: It is an inhibitor of squalene epoxidase. +Option C: It is an inhibitor of cyclooxygenase. +Option D: It is an inhibitor of cysteine proteinases. +" B +5353376 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a phospholipase A2 (PLA2) inhibitor. +Option B: It is an inhibitor of phospholipase A2. +Option C: It is an EC 3.1.1.4 (phospholipase A2) inhibitor. +Option D: It is a phospholipase A2 inhibitor. +" A +5353376 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of phospholipase A2. +Option B: It is a phospholipase A2 (PLA2) inhibitor. +Option C: It is a phospholipase A2 inhibitor. +Option D: It is an EC 3.1.1.4 (phospholipase A2) inhibitor. +" C +5463984 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC2=CC=CC=C2N(C(=O)[C@H]1N[C@@H](CCC3=CC=CC=C3)C(=O)O)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor. +Option B: It is an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor. +Option C: It is an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. +Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +" B +9843089 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" A +8929 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [C-]#N.[Na+] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.17.3.2 (xanthine oxidase) inhibitor. +Option B: It is an EC 3.4.21.5 (thrombin) inhibitor. +Option C: It is an EC 1.11.1.6 (catalase) inhibitor. +Option D: It is an EC 1.15.1.1 (superoxide dismutase) inhibitor. +" D +9547919 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)C(F)(F)P(=O)(O)O)C(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor and an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option B: It is an EC 3.1.3.1 (alkaline phosphatase) inhibitor. +Option C: It is an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor. +Option D: It is an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor. +" C +104842 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor. +Option B: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +Option C: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor. +Option D: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor. +" C +10450920 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=CCC1=C(C(=C(C=C1O)OC)C(=O)CCC2=CC=C(C=C2)O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nitric oxide synthase inhibitor. +Option B: It is a protein synthesis inhibitor. +Option C: It is a nitrification inhibitor. +Option D: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor. +" D +94811 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)NO)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.4.1.3 (glutamate dehydrogenase [NAD(P)(+)] inhibitor). +Option B: It is an EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor. +Option C: It is an EC 1.4.4.2 [glycine dehydrogenase (aminomethyl-transferring)] inhibitor. +Option D: It is an EC 1.8.1.4 (dihydrolipoyl dehydrogenase) inhibitor. +" C +137333889 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC/C(=N\\N(C)C)/C1=C(NC2=C1C=C(C=C2)C(=O)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. +Option B: It is an EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor. +Option C: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. +Option D: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor. +" B +151194 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a receptor protein-tyrosine kinase inhibitor. +Option B: It is a selective tyrosine kinase receptor inhibitor. +Option C: It is a tyrosine kinase receptor inhibitor. +Option D: It is a specific tyrosine kinase receptor inhibitor. +" A +10127622 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a kinase inhibitor. +Option B: It is a dual-kinase inhibitor. +Option C: It is a potent protein kinase C inhibitor. +Option D: It is a mitogen-activated protein kinase inhibitor. +" D +3058754 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option B: It is a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase 2 inhibitor. +Option D: It is a cyclooxygenase inhibitor. +" C +216239 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. +Option B: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. +Option C: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor. +Option D: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor. +" B +5166 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=NC=CC(=N1)C2=C(N=CN2C3CCC(CC3)O)C4=CC=C(C=C4)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option B: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. +Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +Option D: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +" B +11268094 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclin-dependent kinase inhibitor. +Option B: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +Option C: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option D: It is a cyclin dependent kinase inhibitor. +" C +102453304 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H]([C@H]([C@@H]([C@H](O1)OC2=CC=C(C=C2)/C=C/[N+]#[C-])O)O)NC(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 1.14.18.1 (tyrosinase) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is an EC 1.14.14.14 (aromatase) inhibitor. +Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor. +" A +10288191 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)F)C(=O)NOCCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a mitogen-activated protein kinase inhibitor. +Option B: It is an AKT1 kinase inhibitor. +Option C: It is a MEK1 and MEK2 inhibitor. +Option D: It is a B-Raf and MKNK2 kinase inhibitor. +" C +5169 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. +Option B: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. +Option C: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor. +Option D: It is an EC 2.7.11.13 (protein kinase C) inhibitor. +" B +53239799 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor. +Option B: It is a tyrosine kinase inhibitor. +Option C: It is a selective tyrosine kinase receptor inhibitor. +Option D: It is an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. +" D +93460 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCSP(=O)(OCC)OC1=CN(N=C1)C2=CC=C(C=C2)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" B +9571009 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(/C(=N/OC(=O)NC)/C)S(=O)(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +" A +54886 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" D +3025986 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=CN=C(O1)CSC2=CN=C(S2)NC(=O)C3CCNCC3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor. +Option B: It is a potent, reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases. +Option C: It is an ATP-competitive inhibitor of CDK2, CDK7 and CDK9 kinases. +Option D: It is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated cells. +" C +151075 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor. +Option C: It is a cyclooxygenase inhibitor. +Option D: It is a cyclooxygenase 1 inhibitor. +" A +41384 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCN(CCCC)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an acetylcholinesterase inhibitor. +" B +2733491 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O)NC(=O)C.CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O)NC(=O)C.OS(=O)(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.4.22.52 (calpain-1) inhibitor and an EC 3.4.22.53 (calpain-2) inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor. +Option C: It is a calpain inhibitor. +Option D: It is an EC 3.4.22.53 (calpain-2) inhibitor. +" C +3117 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C(=S)SSC(=S)N(CC)CC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an EC 3.1.1.8 (cholinesterase) inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" C +57379018 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)C1=CC=CC2=C1C=CC(=C2)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC.Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a VEGFR and FGFR inhibitor. +Option B: It is a GABA reuptake inhibitor. +Option C: It is a CDK7 inhibitor. +Option D: It is a mitotic inhibitor. +" A +135398739 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@@H](O[C@@H]1CO)N2C=NC3=C2N=CNC3=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 reverse transcriptase inhibitor. +Option B: It is a nucleoside reverse transcriptase inhibitor. +Option C: It is a reverse transcriptase inhibitor. +Option D: It is a nucleoside analogue and reverse transcriptase inhibitor. +" C +1054 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NC=C(C(=C1O)CO)CO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a competitive inhibitor. +Option B: It is a respiration inhibitor. +Option C: It is a mitotic inhibitor. +Option D: It is a potent inhibitor. +" A +441300 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1NC2=C3C(=NC(=N2)N)N(C=N3)[C@@H]4C[C@@H](C=C4)CO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 reverse transcriptase inhibitor. +Option B: It is a nucleoside analogue and reverse transcriptase inhibitor. +Option C: It is a first generation nucleoside analogue and reverse transcriptase inhibitor. +Option D: It is a reverse transcriptase inhibitor. +" B +54726191 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. +Option B: It is a P-Glycoprotein Inhibitor. +Option C: It is a Neuraminidase Inhibitor. +Option D: It is an Intestinal Lipase Inhibitor. +" A +4004 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a Cholinesterase Inhibitor. +Option B: It is an Intestinal Lipase Inhibitor. +Option C: It is a P-Glycoprotein Inhibitor. +Option D: It is a Neuraminidase Inhibitor. +" A +3009 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(C(F)F)(C(=O)O)N)CN +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a Neuraminidase Inhibitor. +Option B: It is a P-Glycoprotein Inhibitor. +Option C: It is an Intestinal Lipase Inhibitor. +Option D: It is an Antiprotozoal and Decarboxylase Inhibitor. +" D +54960 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an ALS inhibitor. +Option B: It is an mTOR inhibitor. +Option C: It is an ACE inhibitor. +Option D: It is an HIV fusion inhibitor. +" A +115355 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC(=O)C(C(=O)C1)C(=O)C2=C(C=C(C=C2)C(F)(F)F)[N+](=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of cellular mitosis. +Option B: It is an inhibitor of CYP2C9. +Option C: It is an inhibitor of the tyrosine catabolism. +Option D: It is an inhibitor of NS5A. +" C +6918837 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=CC=CC=C2N1)CCNCC3=CC=C(C=C3)/C=C/C(=O)NO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a histone deacetylase inhibitor. +Option B: It is an inhibitor of histone deacetylase (HDAC). +Option C: It is an EC 3.5.1.98 (histone deacetylase) inhibitor. +Option D: It is an oral histone deacetylase inhibitor and antineoplastic agent. +" D +6597 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(=O)O)(Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a pyruvate kinase inhibitor. +Option B: It inhibits the enzyme pyruvate dehydrogenase kinase. +Option C: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor. +Option D: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor. +" B +25154714 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C(N5)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nonnucleoside hepatitis C virus polymerase inhibitor. +Option B: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. +Option C: It inhibits the NS5A region of the hepatitis C virus (HCV). +Option D: It is an inhibitor of the hepatitis C virus (HCV) RNA polymerase. +" C +5291 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective tyrosine kinase receptor inhibitor. +Option B: It is a multi-specific tyrosine kinase receptor inhibitor. +Option C: It is a specific tyrosine kinase receptor inhibitor. +Option D: It is a tyrosine kinase receptor inhibitor. +" C +154101 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[C@@H]([C@H]1CCCCN1)C2=CC=CC=C2 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective norepinephrine reuptake inhibitor. +Option B: It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant. +Option C: It is a norepinephrine-dopamine reuptake inhibitor (NDRI). +Option D: It is a serotonin and norepinephrine reuptake inhibitor. +" C +5281081 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C(=O)/C(=C/C1=CC(=C(C(=C1)O)O)[N+](=O)[O-])/C#N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor. +Option B: It is a serotonin and norepinephrine reuptake inhibitor widely used as an antidepressant. +Option C: It is a selective catecholamine (norepinephrine and dopamine) reuptake inhibitor. +Option D: It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant. +" A +5486971 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C[C@@H](CC(=O)O)CN +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of NS5A. +Option B: It is an inhibitor of neuronal activity. +Option C: It is an inhibitor of cellular mitosis. +Option D: It is an inhibitor of unwanted bacteria. +" B +11354606 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@@H]2CC[C@H]3C(=C)C[C@@H](O3)CC[C@]45C[C@@H]6[C@H](O4)[C@H]7[C@@H](O6)[C@@H](O5)[C@@H]8[C@@H](O7)CC[C@@H](O8)CC(=O)C[C@H]9[C@H](C[C@H](C1=C)O2)O[C@@H]([C@@H]9OC)C[C@@H](CN)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of microtubule function. +Option B: It is an inhibitor of NS5A. +Option C: It is an inhibitor of neuronal activity. +Option D: It is an inhibitor of cellular mitosis. +" A +6451164 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a first generation nucleoside analogue and reverse transcriptase inhibitor. +Option B: It is a nucleoside reverse transcriptase inhibitor. +Option C: It is a nonnucleoside reverse transcriptase inhibitor. +Option D: It is a nucleoside analogue and reverse transcriptase inhibitor. +" C +2146 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=NN)(N)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin converting enzyme (ACE) inhibitor. +Option B: It is an angiotensin-converting enzyme (ACE) inhibitor. +Option C: It is an advanced glycation end product inhibitor. +Option D: It is an angiotensin II receptor blocker. +" C +65028 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N)C(=O)OCC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an Intestinal Lipase Inhibitor. +Option B: It is a Cholinesterase Inhibitor. +Option C: It is a P-Glycoprotein Inhibitor. +Option D: It is a Neuraminidase Inhibitor. +" D +5282448 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COS(=O)(=O)O)O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](O2)C(=O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COS(=O)(=O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O[C@@H]5[C@@H]([C@H]([C@@H]([C@H](O5)COS(=O)(=O)O)O)O)NS(=O)(=O)O)O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O)NS(=O)(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of unwanted bacteria. +Option B: It is an inhibitor of cellular mitosis. +Option C: It is an inhibitor of NS5A. +Option D: It is an inhibitor of factor Xa. +" D +5288674 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCCN(C)C)/C)OC)OC(=O)N)\\C)C)O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a heat shock protein (HSP) 90 inhibitor. +Option B: It is a heat shock protein 90 (Hsp90) inhibitor. +Option C: It is a protein synthesis inhibitor. +Option D: It is a Hsp90 inhibitor. +" A +3062316 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor. +Option B: It is a specific tyrosine kinase receptor inhibitor. +Option C: It is a selective tyrosine kinase receptor inhibitor. +Option D: It is a multi-specific tyrosine kinase receptor inhibitor. +" C +5665 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC(CCC(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma. +Option B: It is an orally available small molecule multi-kinase inhibitor that is used as an antineoplastic agent in the treatment of tenosynovial giant cell tumors. +Option C: It is an analog of gamma-aminobutyric acid ([GABA]). +Option D: It is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. +" C +9321 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: NN +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a potent inhibitor. +Option B: It is a competitive inhibitor. +Option C: It is a corrosion inhibitor. +Option D: It is a mitotic inhibitor. +" C +2130 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C2CC3CC1CC(C2)(C3)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an Influenza A M2 Protein Inhibitor. +Option B: It is an inhibitor of cellular mitosis. +Option C: It is an inhibitor of neuronal activity. +Option D: It is an inhibitor of NS5A. +" A +107807 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin converting enzyme (ACE) inhibitor. +Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option C: It is an angiotensin II receptor blocker. +Option D: It is an angiotensin-converting enzyme (ACE) inhibitor. +" D +10472693 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(CCCCCC(CCCCCC(C)(C)C(=O)O)O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.4.4 (adenosine deaminase) inhibitor. +Option B: It is an adenosine triphosphate-citrate lyase (ACL) inhibitor. +Option C: It is an EC 3.5.1.2 (glutaminase) inhibitor. +Option D: It acts as an adenosine deaminase inhibitor. +" B +35370 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N=[N+]=[N-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nucleoside analogue and reverse transcriptase inhibitor. +Option B: It is a reverse transcriptase inhibitor. +Option C: It is a first generation nucleoside analogue and reverse transcriptase inhibitor. +Option D: It is a nucleoside reverse transcriptase inhibitor. +" A +68617 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN[C@H]1CC[C@H](C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective serotonin receptor antagonist. +Option B: It is a serotonin uptake inhibitor. +Option C: It is a selective serotonin reuptake inhibitor (SSRI). +Option D: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +" C +5362119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin converting enzyme (ACE) inhibitor. +Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option C: It is an angiotensin-converting enzyme (ACE) inhibitor. +Option D: It is an angiotensin II receptor blocker. +" C +45375808 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It inhibits the NS5A region of the hepatitis C virus (HCV). +Option B: It is an inhibitor of the hepatitis C virus (HCV) RNA polymerase. +Option C: It is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis. +Option D: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. +" B +10184653 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective tyrosine kinase receptor inhibitor. +Option B: It is a tyrosine kinase inhibitor. +Option C: It is a specific tyrosine kinase receptor inhibitor. +Option D: It is a tyrosine kinase receptor inhibitor. +" D +60838 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiogenesis and metastasis inhibitor. +Option B: It is an irreversible proteasome inhibitor and antineoplastic agent. +Option C: It is an oral histone deacetylase inhibitor and antineoplastic agent. +Option D: It is an antineoplastic enzyme inhibitor. +" D +216210 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral anticoagulant and direct inhibitor of factor Xa. +Option B: It is an inhibitor of cellular mitosis. +Option C: It is an oral anticoagulant and direct factor Xa inhibitor. +Option D: It is a direct inhibitor of thrombin and anticoagulant. +" D +2901 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(C1)(C(=O)O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a specific and reversible inhibitor of nucleic acid methylation. +Option B: It is a reversible monoamine oxidase inhibitor. +Option C: It is a specific, reversible inhibitor of monoamine oxidase A. +Option D: It is a monoamine oxidase inhibitor. +" A +135398744 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a Cholinesterase Inhibitor. +Option B: It is a Phosphodiesterase 4 Inhibitor. +Option C: It is a Phosphodiesterase 5 Inhibitor. +Option D: It is a P-Glycoprotein Inhibitor. +" C +60825 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a reverse transcriptase inhibitor. +Option B: It is a nucleoside analogue and reverse transcriptase inhibitor. +Option C: It is a HIV-1 reverse transcriptase inhibitor. +Option D: It is a nucleoside reverse transcriptase inhibitor. +" B +5966 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC2=CC=CC(=C2)[N+](C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an acetylcholinesterase inhibitor and a cholinesterase inhibitor. +Option B: It is a cholinesterase inhibitor or an anticholinesterase. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an inhibitor of acetylcholinesterase and pseudocholinesterase. +" B +5362124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCC3=CC=CC=C3N(C2=O)CC(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option B: It is an angiotensin II receptor blocker. +Option C: It is an angiotensin converting enzyme (ACE) inhibitor. +Option D: It is an angiotensin-converting enzyme (ACE) inhibitor. +" D +60606 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[C@H](C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an IP3 receptor antagonist. +Option B: It is a P2Y12 Platelet Inhibitor. +Option C: It is a selective serotonin receptor antagonist. +Option D: It is a P2Y12 receptor antagonist. +" B +3219 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOCCN1C2=CC=CC=C2N=C1N3CCCN(CC3)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a trypsin inhibitor. +Option B: It is a dopamine uptake inhibitor. +Option C: It is a histamine-1 receptor inhibitor. +Option D: It is a tropane-based dopamine inhibitor. +" C +25126798 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a multi-kinase inhibitor. +Option B: It is a dual-kinase inhibitor. +Option C: It is a kinase inhibitor. +Option D: It is a Janus kinase inhibitor. +" D +237 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCCC(C)NC1=C2C=C(C=CC2=NC3=C1C=CC(=C3)Cl)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of factor Xa. +Option B: It is an inhibitor of NS5A. +Option C: It is an inhibitor of phospholipase A2. +Option D: It is an inhibitor of cellular mitosis. +" C +3652 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a carotenoid biosynthesis inhibitor. +Option B: It is an EC 1.11.1.6 (catalase) inhibitor. +Option C: It is a mild immunosuppressant. +Option D: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor. +" C +51634 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCN1C[C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of the influenza neuraminidase enzyme. +Option B: It is an inhibitor of glucosylceramide synthase. +Option C: It is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease. +Option D: It is an inhibitor of cellular mitosis. +" B +60877 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@H](O[C@H](S1)CO)N2C=C(C(=NC2=O)N)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a reverse transcriptase inhibitor. +Option B: It is a nucleoside analogue and reverse transcriptase inhibitor. +Option C: It is a HIV-1 reverse transcriptase inhibitor. +Option D: It is a nucleoside reverse transcriptase inhibitor. +" A +5311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.5.1.98 (histone deacetylase) inhibitor. +Option B: It is an oral histone deacetylase inhibitor and antineoplastic agent. +Option C: It is an inhibitor of histone deacetylase (HDAC). +Option D: It is a histone deacetylase inhibitor. +" D +5859 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)S(=O)(=O)C1=CC=C(C=C1)OP(=S)(OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an Intestinal Lipase Inhibitor. +Option B: It is a Cholinesterase Inhibitor. +Option C: It is a Neuraminidase Inhibitor. +Option D: It is a P-Glycoprotein Inhibitor. +" B +2244 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OC1=CC=CC=C1C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclooxygenase 2 inhibitor. +Option B: It is a cyclooxygenase inhibitor. +Option C: It is a cyclooxygenase 1 inhibitor. +Option D: It is an inhibitor of cyclooxygenase. +" D +148124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of NS5A. +Option B: It is an inhibitor of cellular mitosis. +Option C: It is an inhibitor of factor Xa. +Option D: It is an inhibitor of unwanted bacteria. +" B +160355 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +Option B: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +Option C: It is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor. +Option D: It is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated cells. +" D +49855250 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)/C=C/C(=O)NO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option B: It is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in clinical trials, allowing oral dosing. +Option C: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. +Option D: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease. +" B +38779 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an acetylcholinesterase (AChE) inhibitor. +" D +119031 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C[C@H]([C@@H](C(=O)NO)O)C(=O)N[C@H](C(=O)NC)C(C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin II receptor blocker. +Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option C: It is an angiogenesis and metastasis inhibitor. +Option D: It is an angiotensin converting enzyme (ACE) inhibitor. +" C +3961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +Option B: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option C: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease. +Option D: It is an angiotensin II receptor blocker used in the therapy of hypertension and diabetic nephropathy. +" D +71496458 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). +Option B: It is a tyrosine kinase receptor inhibitor that is used in the therapy of advanced or metastatic pancreatic or non-small cell lung cancer. +Option C: It is a small molecule inhibitor of several tyrosine kinase receptors involved in tumor cell growth used in the therapy of advanced breast cancer and other solid tumors. +Option D: It is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of advanced non-small cell lung cancer. +" A +9926791 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +Option B: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease. +Option C: It is an oral kinase inhibitor approved for use in combination with rituximab in relapsed or refractory chronic lymphocytic leukemia (CLL) and as monotherapy for relapsed follicular B cell, small lymphocytic lymphoma and indolent non-Hodgkin lymphoma. +Option D: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +" D +5484727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2[C@H]3CCCC[C@@H]3C[C@H]2C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and heart failure. +Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option C: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma. +Option D: It is an angiotensin II receptor blocker used in the therapy of hypertension and diabetic nephropathy. +" A +5853 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(C(C(Cl)(Cl)Cl)O)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an irreversible organophosphate acetylcholinesterase inhibitor. +Option B: It is an acetylcholinesterase (AChE) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" A +49806720 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC2=C(C=C1N3CCC(CC3)N4CCOCC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of advanced non-small cell lung cancer. +Option B: It is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). +Option C: It is a tyrosine kinase receptor inhibitor that is used in the therapy of advanced or metastatic pancreatic or non-small cell lung cancer. +Option D: It is a small molecule inhibitor of several tyrosine kinase receptors involved in tumor cell growth used in the therapy of advanced breast cancer and other solid tumors. +" A +11273 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CCC(=O)C(=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +Option B: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor. +Option C: It was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. +Option D: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +" C +444 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C(=O)C1=CC(=CC=C1)Cl)NC(C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a serotonin and norepinephrine reuptake inhibitor widely used as an antidepressant. +Option B: It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant. +Option C: It is a selective catecholamine (norepinephrine and dopamine) reuptake inhibitor. +Option D: It is a serotonin and norepinephrine reuptake inhibitor. +" C +5462501 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)N[C@@H](CCC2=CC=CC=C2)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an HIV fusion inhibitor. +Option B: It is an mTOR inhibitor. +Option C: It is an ALS inhibitor. +Option D: It is an ACE inhibitor. +" D +6918314 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +Option B: It is a selective serotonin receptor antagonist. +Option C: It is a serotonin uptake inhibitor. +Option D: It is a selective serotonin reuptake inhibitor (SSRI). +" A +439501 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@H]2C[C@H]([C@@]3([C@@H]4[C@@H](CC[C@@]3(C2)O)[C@]5(CC[C@@H]([C@]5(C[C@H]4O)C)C6=CC(=O)OC6)O)CO)O)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor. +Option B: It is an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. +Option C: It is an EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor. +Option D: It is an inhibitor of the NA(+)-K(+)-exchanging ATPase. +" D +56330 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCCN3CCC[C@H](N3C2=O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an mTOR inhibitor. +Option B: It is an HIV fusion inhibitor. +Option C: It is an ACE inhibitor. +Option D: It is an ALS inhibitor. +" C +3386 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +Option B: It is a selective serotonin reuptake inhibitor (SSRI). +Option C: It is a selective serotonin receptor antagonist. +Option D: It is a serotonin uptake inhibitor. +" B +5388962 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin converting enzyme (ACE) inhibitor. +Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option C: It is an angiotensin-converting enzyme (ACE) inhibitor. +Option D: It is an angiotensin II receptor blocker. +" C +10548 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(OCC)SCC[N+](C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a Cholinesterase Inhibitor. +Option B: It is a Phosphodiesterase 5 Inhibitor. +Option C: It is a Phosphodiesterase 4 Inhibitor. +Option D: It is a P-Glycoprotein Inhibitor. +" A +5280980 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]2N(C1=O)[C@H](/C(=C/CO)/O2)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a HIV-1 protease inhibitor. +Option B: It is a protease inhibitor. +Option C: It acts as a suicide inhibitor of bacterial beta-lactamase enzymes. +Option D: It is a beta-lactamase inhibitor. +" D +34526 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C1=NC(=CC(=N1)OP(=S)(OC)OC)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an acetylcholinesterase (AChE) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +" B +135398687 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]([C@@H](C1=NC2=C(NC1)N=C(NC2=O)N)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of cellular mitosis. +Option B: It is an inhibitor of the matrix metalloproteinases. +Option C: It is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA). +Option D: It is an inhibitor of NS5A. +" C +54892 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin-converting enzyme (ACE) inhibitor. +Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option C: It is an angiotensin converting enzyme (ACE) inhibitor. +Option D: It is an angiotensin II receptor blocker. +" A +12450 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)C1=CC=C(C=C1)C(=C2C=CC(=[N+](CC)CC)C=C2)C3=CC=CC=C3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of Gram positive microorganisms. +Option B: It is an inhibitor of microtubule function. +Option C: It is an inhibitor of cellular mitosis. +Option D: It is an inhibitor of neuronal activity. +" A +449381 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a Cholinesterase Inhibitor. +Option B: It is a Neuraminidase Inhibitor. +Option C: It is a P-Glycoprotein Inhibitor. +Option D: It is an Intestinal Lipase Inhibitor. +" B +54680690 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)[C@H]1[C@@H]2C[C@@H]3[C@@H](C4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)Cl)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is used as an inhibitor of arginine vasopressin in the therapy of hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). +Option B: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. +Option C: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option D: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease. +" A +3883 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a proton pump inhibitor. +Option B: It is a proton pump inhibitor (PPI). +Option C: It is a potent inhibitor. +Option D: It is a trypsin inhibitor. +" B +5324346 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COCCCC/C(=N\\OCCN)/C1=CC=C(C=C1)C(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a serotonin uptake inhibitor. +Option B: It is a selective serotonin reuptake inhibitor (SSRI). +Option C: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +Option D: It is a selective serotonin receptor antagonist. +" B +54746 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(C1)CC=C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +Option B: It is a serotonin and norepinephrine reuptake inhibitor. +Option C: It is a selective serotonin reuptake inhibitor (SSRI). +Option D: It is a long-acting dopamine agonist and prolactin inhibitor. +" D +135398559 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H](N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is used to counteract the toxic effects of folic acid antagonists. +Option B: It is a selective serotonin reuptake inhibitor (SSRI). +Option C: It is a selective inhibitor of uric acid reabsorption. +Option D: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +" A +65016 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CCOC2)O)S(=O)(=O)C3=CC=C(C=C3)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an HIV protease inhibitor. +Option B: It is a protease inhibitor. +Option C: It is a HIV-1 integrase inhibitor. +Option D: It is a HIV-1 protease inhibitor. +" B +5329102 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCNC(=O)C1=C(NC(=C1C)/C=C\\2/C3=C(C=CC(=C3)F)NC2=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor. +Option B: It is a multi-specific tyrosine kinase receptor inhibitor. +Option C: It is a specific tyrosine kinase receptor inhibitor. +Option D: It is a selective tyrosine kinase receptor inhibitor. +" B +25183872 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: B([C@H](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a cyclin dependent kinase inhibitor. +Option B: It is a small molecule kinase inhibitor. +Option C: It is a small molecule proteasome inhibitor. +Option D: It is a cyclin-dependent kinase inhibitor. +" C +4659569 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C(=O)C2=CC(=C(C(=C2)O)O)[N+](=O)[O-] +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a catechol-O-methyltransferase inhibitor. +Option B: It is a selective catecholamine (norepinephrine and dopamine) reuptake inhibitor. +Option C: It is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor. +Option D: It is a serotonin and norepinephrine reuptake inhibitor. +" A +213039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an antiretroviral protease inhibitor. +Option B: It is a HIV-1 protease inhibitor. +Option C: It is an HIV protease inhibitor. +Option D: It is a HIV-1 integrase inhibitor. +" A +154234 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)[C@@H]([C@H]1[C@@H](C[C@@H]([C@H]1O)C(=O)O)N=C(N)N)NC(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of cellular mitosis. +Option B: It is an inhibitor of the matrix metalloproteinases. +Option C: It is an inhibitor of the influenza neuraminidase enzyme. +Option D: It is an inhibitor of neuronal activity. +" C +54739 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an imidazolinone herbicide and inhibits the acetohydroxy acid synthase (AHAS) enzyme. +Option B: It is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes. +Option C: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma. +Option D: It is an orally available small molecule multi-kinase inhibitor that is used as an antineoplastic agent in the treatment of tenosynovial giant cell tumors. +" A +5826 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](CC1=CC=CC=C1)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It may inhibit monoamine oxidase (MAO). +Option B: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +Option C: It is a specific, reversible inhibitor of monoamine oxidase A. +Option D: It is a reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA). +" A +25102847 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma. +Option B: It is a proteasome inhibitor and antineoplastic agent used in the treatment of refractory multiple myeloma and certain lymphomas. +Option C: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor. +Option D: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma. +" D +4679 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC(F)F)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option B: It is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity used in the therapy of gastroesophageal reflux and peptic ulcer disease. +Option C: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. +Option D: It is a proton pump inhibitor (PPI) used in the therapy of gastroesophageal reflux and peptic ulcer disease. +" D +6047 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity used in the therapy of gastroesophageal reflux and peptic ulcer disease. +Option B: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. +Option C: It is an alpha glucosidase inhibitor which decreases intestinal absorption of carbohydrates and is used as an adjunctive therapy in the management of type 2 diabetes. +Option D: It is used for the treatment of parkinsonian disorders and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system. +" D +5656 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a norepinephrine-dopamine reuptake inhibitor (NDRI). +Option B: It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant. +Option C: It is a serotonin and norepinephrine reuptake inhibitor. +Option D: It is a serotonin and norepinephrine reuptake inhibitor widely used as an antidepressant. +" D +56640146 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=CC(=CC(=C1OC)C2=CC3=C(C=C2)C=C(C=C3)NS(=O)(=O)C)N4C=CC(=O)NC4=O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a non-nucleoside NS5B inhibitor used to render the polymerase unable to elongate viral RNA. +Option B: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. +Option C: It is a hepatitis C virus nonstructural protein 5A inhibitor. +Option D: It is a nonnucleoside hepatitis C virus polymerase inhibitor. +" A +10113978 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a multi-kinase inhibitor used in the therapy of advanced renal cell carcinoma and soft tissue sarcomas. +Option B: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma. +Option C: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma. +Option D: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor. +" A +11167602 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma. +Option B: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma. +Option C: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor. +Option D: It is a proteasome inhibitor and antineoplastic agent used in the treatment of refractory multiple myeloma and certain lymphomas. +" C +10127622 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral kinase inhibitor approved for use in combination with rituximab in relapsed or refractory chronic lymphocytic leukemia (CLL) and as monotherapy for relapsed follicular B cell, small lymphocytic lymphoma and indolent non-Hodgkin lymphoma. +Option B: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +Option C: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +Option D: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease. +" B +216239 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a moderate inhibitor of acetylcholinesterase and a strong inhibitor of platelet-activating factor induced platelet aggregation. +Option B: It is a potent, reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases. +Option C: It is an oral tyrosine kinase inhibitor selective for vascular endothelial growth factor (VEGF) receptors -1, -2 and -3. +Option D: It is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor. +" D +54841 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1O[C@H](CCNC)C2=CC=CC=C2 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a norepinephrine-dopamine reuptake inhibitor (NDRI). +Option B: It is a selective norepinephrine reuptake inhibitor. +Option C: It is a serotonin and norepinephrine reuptake inhibitor. +Option D: It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant. +" B +60490 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC2=CC=CC=C2S1)N(C(=O)N)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an antiinflammatory leukotriene pathway inhibitor classified as an inhibitor of the enzyme 5-lipoxygenase. +Option B: It is used as an inhibitor of arginine vasopressin in the therapy of hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). +Option C: It is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity used in the therapy of gastroesophageal reflux and peptic ulcer disease. +Option D: It is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. +" A +5372405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNP(=S)(OC)O/C(=C/C(=O)OC(C)C)/C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor. +Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor. +Option C: It is an acetylcholinesterase inhibitor. +Option D: It is an acetylcholinesterase (AChE) inhibitor. +" C +31101 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of cellular mitosis. +Option B: It inhibits prolactin secretion. +Option C: It is a platelet aggregation inhibitor. +Option D: It is an inhibitor of platelet aggregation. +" B +43815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a selective serotonin receptor antagonist. +Option B: It is a serotonin uptake inhibitor. +Option C: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist. +Option D: It is a selective serotonin reuptake inhibitor (SSRI). +" D +5472 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CC2=C1SC=C2)CC3=CC=CC=C3Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a platelet aggregation inhibitor. +Option B: It is a leukocyte elastase inhibitor. +Option C: It is a neprilysin inhibitor. +Option D: It is a lipoxygenase inhibitor and a platelet aggregation inhibitor. +" A +5029 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCCCOC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. +Option B: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +Option C: It is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity used in the therapy of gastroesophageal reflux and peptic ulcer disease. +Option D: It is a proton pump inhibitor (PPI) used in the therapy of gastroesophageal reflux and peptic ulcer disease. +" C +6435415 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C[C@@H]1C(=O)N/C(=C\\CCCCSC[C@@H](C(=O)O)N)/C(=O)O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. +Option B: It is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. +Option C: It is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity used in the therapy of gastroesophageal reflux and peptic ulcer disease. +Option D: It is a proton pump inhibitor (PPI) used in the therapy of gastroesophageal reflux and peptic ulcer disease. +" B +3202 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[N+](C)(C)C1=CC(=CC=C1)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an Intestinal Lipase Inhibitor. +Option B: It is a P-Glycoprotein Inhibitor. +Option C: It is a Cholinesterase Inhibitor. +Option D: It is a Neuraminidase Inhibitor. +" C +9854012 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CSCCNC1=C2C(=NC(=N1)SCCC(F)(F)F)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(C(P(=O)(O)O)(Cl)Cl)O)O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an IP3 receptor antagonist. +Option B: It is a P2Y12 Platelet Inhibitor. +Option C: It is a selective serotonin receptor antagonist. +Option D: It is a P2Y12 receptor antagonist. +" B +449459 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC/C(=C(\\C1=CC=C(C=C1)O)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +Option B: It is a new estrogen inhibitor under investigation for a variety of estrogen-dependent conditions, including cyclic breast pain and gynecomastia. +Option C: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor. +Option D: It was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. +" B +3052776 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C#CCN[C@@H]1CCC2=CC=CC=C12 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease. +Option B: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +Option C: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease. +Option D: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +" A +445643 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +Option B: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease. +Option C: It is a moderate inhibitor of acetylcholinesterase and a strong inhibitor of platelet-activating factor induced platelet aggregation. +Option D: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation. +" D +5328940 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral kinase inhibitor approved for use in combination with rituximab in relapsed or refractory chronic lymphocytic leukemia (CLL) and as monotherapy for relapsed follicular B cell, small lymphocytic lymphoma and indolent non-Hodgkin lymphoma. +Option B: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1. +Option C: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +Option D: It is a dual kinase inhibitor of both the BCR-ABL and Src tyrosine kinases and is used in the therapy of Philadelphia chromosome-positive chronic myelogenous leukemia. +" D +176870 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of advanced non-small cell lung cancer. +Option B: It is a tyrosine kinase receptor inhibitor that is used in the therapy of advanced or metastatic pancreatic or non-small cell lung cancer. +Option C: It is a small molecule inhibitor of several tyrosine kinase receptors involved in tumor cell growth used in the therapy of advanced breast cancer and other solid tumors. +Option D: It is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC). +" B +135398508 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C1[C@H](C[C@@H]([C@H]1CO)O)N2C=NC3=C2N=C(NC3=O)N +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease. +Option B: It is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). +Option C: It is a small molecule inhibitor of the If ion channel which is used to decrease the heart rate in patients with symptomatic heart failure who have a resting heart rate above 70 beats per minute despite optimal doses or intolerance of beta blockers. +Option D: It is an oral kinase inhibitor approved for use in combination with rituximab in relapsed or refractory chronic lymphocytic leukemia (CLL) and as monotherapy for relapsed follicular B cell, small lymphocytic lymphoma and indolent non-Hodgkin lymphoma. +" B +4456 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an Intestinal Lipase Inhibitor. +Option B: It is a Cholinesterase Inhibitor. +Option C: It is a P-Glycoprotein Inhibitor. +Option D: It is a Neuraminidase Inhibitor. +" B +2131 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)CC2=CC=CC=C2Cl +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an Intestinal Lipase Inhibitor. +Option B: It is a Cholinesterase Inhibitor. +Option C: It is a P-Glycoprotein Inhibitor. +Option D: It is a Neuraminidase Inhibitor. +" B +44093 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is an angiotensin II receptor blocker used in the therapy of hypertension. +Option B: It is an angiotensin-converting enzyme (ACE) inhibitor. +Option C: It is an angiotensin II receptor blocker. +Option D: It is an angiotensin converting enzyme (ACE) inhibitor. +" B +5530 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(C1N)C2=CC=CC=C2 +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a reversible monoamine oxidase inhibitor. +Option B: It is a monoamine oxidase inhibitor. +Option C: It is a specific, reversible inhibitor of monoamine oxidase A. +Option D: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor). +" D +77991 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a P-Glycoprotein Inhibitor. +Option B: It is an Intestinal Lipase Inhibitor. +Option C: It is a Cholinesterase Inhibitor. +Option D: It is a Neuraminidase Inhibitor. +" C +5625 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)NS(=O)(=O)C +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a nonnucleoside reverse transcriptase inhibitor. +Option B: It is a nucleoside analogue and reverse transcriptase inhibitor. +Option C: It is a nucleoside reverse transcriptase inhibitor. +Option D: It is a first generation nucleoside analogue and reverse transcriptase inhibitor. +" A +2662 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F +Question about this molecule: Which kind of inhibitor is this molecule? +Option A: It is a CDK7 inhibitor. +Option B: It is a selective COX-2 inhibitor. +Option C: It is a COX-2 inhibitor. +Option D: It is a competitive inhibitor. +" B +17040 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)OC(=O)NC)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as a selective insecticide. +Option B: It is a phytogenic insecticide. +Option C: It is a contact and systemic insecticide. +Option D: It is a carbamate insecticide. +" D +14322 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC=C1)OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a contact and systemic insecticide. +Option B: It is a phytogenic insecticide. +Option C: It is used as a selective insecticide. +Option D: It is a carbamate insecticide. +" D +5368008 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(/C(=N\\OC(=O)NC)/C)SC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a carbamate insecticide. +Option B: It is a contact and systemic insecticide. +Option C: It is used as a selective insecticide. +Option D: It is a phytogenic insecticide. +" A +31099 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)OC1=CC=CC(=C1)N=CN(C)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a phytogenic insecticide. +Option B: It is used as a selective insecticide. +Option C: It is a contact and systemic insecticide. +Option D: It is a carbamate insecticide. +" D +5392 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=S)(OC)OC1=CC=C(C=C1)SC2=CC=C(C=C2)OP(=S)(OC)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphorus insecticide. +Option B: It is an organophosphate insecticide. +Option C: It is an organophosphate insecticide used to control various pests. +Option D: It is an organothiophosphate insecticide. +" D +16126809 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=N\\OC(=O)NSNC(=O)O/N=C(/SC)\\C)/SC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a carbamate insecticide. +Option B: It is a contact and systemic insecticide. +Option C: It is used as a selective insecticide. +Option D: It is a phytogenic insecticide. +" A +5364932 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)/C(=N\\OC(=O)NC)/CSC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a contact and systemic insecticide. +Option B: It is a carbamate insecticide. +Option C: It is a phytogenic insecticide. +Option D: It is used as a selective insecticide. +" B +31070 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(NC(C)C)OC1=CC(=C(C=C1)SC)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organothiophosphate insecticide. +Option B: It is an organophosphorus insecticide. +Option C: It is an organophosphate insecticide. +Option D: It is an organophosphate insecticide used to control various pests. +" C +2314 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(OC2=C(O1)C(=CC=C2)OC(=O)NC)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as a selective insecticide. +Option B: It is a carbamate insecticide. +Option C: It is a phytogenic insecticide. +Option D: It is a contact and systemic insecticide. +" B +17517 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C1=CC=CC=C1OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a carbamate insecticide. +Option B: It is used as a selective insecticide. +Option C: It is a phytogenic insecticide. +Option D: It is a contact and systemic insecticide. +" A +12901 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=S)(OC)SCN1C(=O)C2=CC=CC=C2C1=O +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphorus insecticide. +Option B: It is an organothiophosphate insecticide. +Option C: It is an organophosphate insecticide. +Option D: It is an organophosphate insecticide used to control various pests. +" B +1982 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NP(=O)(OC)SC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphorus insecticide. +Option B: It is an organophosphate insecticide. +Option C: It is an organophosphate insecticide used to control various pests. +Option D: It is an organothiophosphate insecticide. +" D +4944 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC1=CC=CC=C1OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a carbamate insecticide. +Option B: It is a contact and systemic insecticide. +Option C: It is used as a selective insecticide. +Option D: It is a phytogenic insecticide. +" A +135779804 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=N[N+](=O)[O-])NCC1=CN=C(S1)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a neonicotinoid insecticide. +Option B: It is a fumigant insecticide. +Option C: It is used as a selective insecticide. +Option D: It is a phytogenic insecticide. +" A +522251 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C=C1C)Cl)OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a carbamate insecticide. +Option B: It is used as a selective insecticide. +Option C: It is a phytogenic insecticide. +Option D: It is a contact and systemic insecticide. +" A +13059873 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1CSSSC1.Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a nicotinic acetylcholine receptor agonist insecticide. +Option B: It is a potent acetylcholinesterase-inhibiting insecticide. +Option C: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests. +Option D: It is an organophosphate acetylcholinesterase inhibitor used as an insecticide. +" A +6564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CCl)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a fumigant insecticide. +Option B: It is a phytogenic insecticide. +Option C: It is a contact and systemic insecticide. +Option D: It is used as a selective insecticide. +" A +35969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1CSSSC1.C(=O)(C(=O)O)O +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate acetylcholinesterase inhibitor used as an insecticide. +Option B: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests. +Option C: It is a potent acetylcholinesterase-inhibiting insecticide. +Option D: It is a nicotinic acetylcholine receptor agonist insecticide. +" D +90284302 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C(C1C(=O)OCC2=C(C(=C(C(=C2F)F)COC)F)F)/C=C\\C(F)(F)F)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a pyrethroid ether insecticide. +Option B: It is a pyrethroid ester insecticide. +Option C: It is a synthetic pyrethroid insecticide. +Option D: It is a pyrethroid insecticide. +" B +6423 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([N+](=O)[O-])(Cl)(Cl)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a phytogenic insecticide. +Option B: It is a contact and systemic insecticide. +Option C: It is a fumigant insecticide. +Option D: It is used as a selective insecticide. +" C +17435 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C(C1=CC=CC=C1)SP(=S)(OC)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate insecticide. +Option B: It is an organophosphate insecticide used to control various pests. +Option C: It is an organothiophosphate insecticide. +Option D: It is an organophosphorus insecticide. +" C +17434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)N(C)C(=O)CSP(=S)(OCC)OCC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphorus insecticide. +Option B: It is an organothiophosphate insecticide. +Option C: It is an organophosphate insecticide used to control various pests. +Option D: It is an organophosphate insecticide. +" B +47759 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC(=O)N(C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a carbamate insecticide. +Option B: It is a phytogenic insecticide. +Option C: It is a contact and systemic insecticide. +Option D: It is used as a selective insecticide. +" A +9571009 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(/C(=N/OC(=O)NC)/C)S(=O)(=O)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as a selective insecticide. +Option B: It is a phytogenic insecticide. +Option C: It is a carbamate insecticide. +Option D: It is a contact and systemic insecticide. +" C +54886 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a contact and systemic insecticide. +Option B: It is a phytogenic insecticide. +Option C: It is used as a selective insecticide. +Option D: It is a carbamate insecticide. +" D +41384 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCN(CCCC)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a contact and systemic insecticide. +Option B: It is used as a selective insecticide. +Option C: It is a carbamate insecticide. +Option D: It is a phytogenic insecticide. +" C +5281873 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C(/C(F)(F)F)\\Cl)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a pyrethroid ether insecticide. +Option B: It is a synthetic pyrethroid insecticide. +Option C: It is a pyrethroid insecticide. +Option D: It is a pyrethroid ester insecticide. +" B +4793 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)SCN1C2=C(C=C(C=C2)Cl)OC1=O +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate insecticide used to control various pests. +Option B: It is an organothiophosphate insecticide. +Option C: It is an organophosphate insecticide. +Option D: It is an organophosphorus insecticide. +" C +12901 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=S)(OC)SCN1C(=O)C2=CC=CC=C2C1=O +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a contact and systemic insecticide. +Option B: It is a non-specific insecticide. +Option C: It is a phytogenic insecticide. +Option D: It is used as a selective insecticide. +" B +4004 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)CC(C(=O)OCC)SP(=S)(OC)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide that does not occur naturally in the environment. +Option B: It is an insecticide that does not occur naturally. +Option C: It is an insecticide used on a variety of crops. +Option D: It is an insecticide and acaricide. +" B +637511 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)/C=C/C=O +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an effective insecticide and also repels animals like cats and dogs. +Option B: It is an insecticide used on a variety of crops. +Option C: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option D: It is an agricultural insecticide, particularly for rice and tea. +" A +5371562 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C\\C(=O)NC)/OP(=O)(OC)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a fast-acting insecticide with both systemic and contact action. +Option B: It is a contact and systemic insecticide. +Option C: It is a non-specific insecticide. +Option D: It is used as a selective insecticide. +" A +51605 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)NCCOC1=CC=C(C=C1)OC2=CC=CC=C2 +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a phytogenic insecticide. +Option B: It is used as a selective insecticide. +Option C: It is a contact and systemic insecticide. +Option D: It is a non-specific insecticide. +" B +25960 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [O-][Se](=O)(=O)[O-].[Na+].[Na+] +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide used on a variety of crops. +Option B: It is used as an insecticide in some horticultural applications. +Option C: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option D: It is an effective insecticide and also repels animals like cats and dogs. +" B +1982 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NP(=O)(OC)SC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as a selective insecticide. +Option B: It is a contact and systemic insecticide. +Option C: It is a non-specific insecticide. +Option D: It is a phytogenic insecticide. +" B +9395 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-] +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option B: It is a potent acetylcholinesterase-inhibiting insecticide. +Option C: It is an organophosphate acetylcholinesterase inhibitor used as an insecticide. +Option D: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests. +" B +4130 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=S)(OC)OC1=CC=C(C=C1)[N+](=O)[O-] +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide that does not occur naturally in the environment. +Option B: It is an insecticide used on a variety of crops. +Option C: It is an insecticide that does not occur naturally. +Option D: It is an insecticide and acaricide. +" A +115224 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CSC(=NC#N)N1CC2=CN=C(C=C2)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as a selective insecticide. +Option B: It is a neonicotinoid insecticide. +Option C: It is a phytogenic insecticide. +Option D: It is a fumigant insecticide. +" B +14322 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC=C1)OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide for the control of rice leafhoppers, planthoppers, codling moth, citrus mealybug, onion thrips, fruit flies, bollworms, and aphids. +Option B: It is an organophosphate, household and public health insecticide designed to control cockroaches, flies, ants, ticks, moths, fleas and mosquitoes on contact. +Option C: It is an alpha-cyano-3-phenoxyphenyl pyrethroid insecticide used in the control of ectoparasites on cattle, sheep, goats, horses, and dogs. +Option D: It is an organophosphate insecticide that has been used since 1959 to control insects on rice, cereals, fruits, vegetables, stored grains, cotton, to control insects in forests and for fly, mosquito, and cockroach control in public health programs. +" A +17563 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1)OC(=O)NC)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option B: It is an agricultural insecticide, particularly for rice and tea. +Option C: It is an agricultural insecticide used on rice, cocoa, sugar cane, vegetables and other crops. +Option D: It is an insecticide used on a variety of crops. +" B +3034287 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC1=CN=C(C=C1)Cl)/C(=C/[N+](=O)[O-])/NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an effective insecticide and also repels animals like cats and dogs. +Option B: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option C: It is an agricultural insecticide, particularly for rice and tea. +Option D: It is an insecticide used on a variety of crops. +" B +13754 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(OCC)OC1=NC(=NC(=C1)C)C(C)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate insecticide. +Option B: It is an organophosphorus insecticide. +Option C: It is a nonsystemic organophosphate insecticide. +Option D: It is an organophosphate insecticide used to control various pests. +" C +3346 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)OP(=S)(OC)OC)SC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate insecticide used to control various pests. +Option B: It is an organothiophosphate insecticide. +Option C: It is an organophosphate insecticide. +Option D: It is an organophosphorus insecticide. +" B +3039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(OC)OC=C(Cl)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate insecticide. +Option B: It is an organophosphorus insecticide. +Option C: It is an organothiophosphate insecticide. +Option D: It is an organophosphate insecticide used to control various pests. +" A +8292 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)OC1=CC=C(C=C1)S(=O)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option B: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +Option C: It is an insecticide, nematocide, and mosquito larvicide. +Option D: It is used as an insecticide and acaricide on vegetables, alfalfa, deciduous fruits and nuts. +" C +4790 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)SCSCC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide and acaricide. +Option B: It is an insecticide used on a variety of crops. +Option C: It is primarily used as an insecticide for corn. +Option D: It is an insecticide that acts as a molting hormone. +" A +48132 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C(C(Br)(Br)Br)Br)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a pyrethroid ether insecticide. +Option B: It is a pyrethroid insecticide. +Option C: It is a synthetic pyrethroid insecticide. +Option D: It is a pyrethroid ester insecticide. +" B +4944 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC1=CC=CC=C1OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option B: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +Option C: It is used as an insecticide and acaricide on vegetables, alfalfa, deciduous fruits and nuts. +Option D: It is an insecticide and acaricide effective against thrips, mites, aphids, and leafhoppers. +" B +38779 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide used to control many pests, mainly Lepidoptera and mites. +Option B: It is used as an insecticide for the fumigation of grains, animal feed, and leaf-stored tobacco. +Option C: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option D: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +" A +5853 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(C(C(Cl)(Cl)Cl)O)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate insecticide used to control various pests. +Option B: It is an organophosphorus insecticide. +Option C: It is an organothiophosphate insecticide. +Option D: It is an organophosphate insecticide. +" A +24404 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: P +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as an insecticide and acaricide on vegetables, alfalfa, deciduous fruits and nuts. +Option B: It is used as an insecticide for the fumigation of grains, animal feed, and leaf-stored tobacco. +Option C: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +Option D: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +" B +91773 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=CC=C(C=C1)C(=O)NN(C(=O)C2=CC(=CC(=C2)C)C)C(C)(C)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide that acts as a molting hormone. +Option B: It is primarily used as an insecticide for corn. +Option C: It is an insecticide and acaricide. +Option D: It is an insecticide used on a variety of crops. +" A +6129 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)OC1=CC=CC2=CC=CC=C21 +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an agricultural insecticide, particularly for rice and tea. +Option B: It is an effective insecticide and also repels animals like cats and dogs. +Option C: It is an insecticide used on a variety of crops. +Option D: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +" C +40326 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C(C1C(=O)OCC2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. +Option B: It is a pyrethroid insecticide. +Option C: It is a synthetic pyrethroid insecticide. +Option D: It is a pyrethroid insecticide with many uses, including control of the adult mosquito population. +" A +5355863 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C\\C(=O)OC)/OP(=O)(OC)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide and acaricide effective against thrips, mites, aphids, and leafhoppers. +Option B: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +Option C: It is used as an insecticide and acaricide on vegetables, alfalfa, deciduous fruits and nuts. +Option D: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +" C +16248 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1SC)C)OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as an insecticide and acaricide on vegetables, alfalfa, deciduous fruits and nuts. +Option B: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +Option C: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option D: It is an insecticide and acaricide effective against thrips, mites, aphids, and leafhoppers. +" C +213021 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=NC#N)N(C)CC1=CN=C(C=C1)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a neonicotinoid insecticide. +Option B: It is a phytogenic insecticide. +Option C: It is used as a selective insecticide. +Option D: It is a fumigant insecticide. +" A +3289 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCSP(=O)(OCC)SCCC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate acetylcholinesterase inhibitor used as an insecticide. +Option B: It is a potent acetylcholinesterase-inhibiting insecticide. +Option C: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests. +Option D: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +" A +17531 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)SCN1C(=O)C2=CC=CC=C2N=N1 +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option B: It is used as an insecticide in some horticultural applications. +Option C: It is used as a non-systemic insecticide with good ovicidal properties and long persistence. +Option D: It is used as an insecticide for the fumigation of grains, animal feed, and leaf-stored tobacco. +" C +37123 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC=C(C=C2)Cl)F +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a non-specific insecticide. +Option B: It is used as a selective insecticide. +Option C: It is a phytogenic insecticide. +Option D: It is a contact and systemic insecticide. +" B +6423 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([N+](=O)[O-])(Cl)(Cl)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option B: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +Option C: It is used as an insecticide and acaricide on vegetables, alfalfa, deciduous fruits and nuts. +Option D: It is a chemical compound currently used as a broad-spectrum antimicrobial, fungicide, herbicide, insecticide, and nematicide. +" D +5371560 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C\\C(=O)N(C)C)/OP(=O)(OC)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a potent acetylcholinesterase-inhibiting insecticide. +Option B: It is an organophosphate acetylcholinesterase inhibitor used as an insecticide. +Option C: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option D: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests. +" B +5372405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNP(=S)(OC)O/C(=C/C(=O)OC(C)C)/C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an alpha-cyano-3-phenoxyphenyl pyrethroid insecticide used in the control of ectoparasites on cattle, sheep, goats, horses, and dogs. +Option B: It is an organophosphate insecticide that has been used since 1959 to control insects on rice, cereals, fruits, vegetables, stored grains, cotton, to control insects in forests and for fly, mosquito, and cockroach control in public health programs. +Option C: It is an organophosphate, household and public health insecticide designed to control cockroaches, flies, ants, ticks, moths, fleas and mosquitoes on contact. +Option D: It is an insecticide for the control of rice leafhoppers, planthoppers, codling moth, citrus mealybug, onion thrips, fruit flies, bollworms, and aphids. +" C +31070 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(NC(C)C)OC1=CC(=C(C=C1)SC)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests. +Option B: It is an organophosphate insecticide that has been used since 1959 to control insects on rice, cereals, fruits, vegetables, stored grains, cotton, to control insects in forests and for fly, mosquito, and cockroach control in public health programs. +Option C: It is an organophosphate, household and public health insecticide designed to control cockroaches, flies, ants, ticks, moths, fleas and mosquitoes on contact. +Option D: It is an insecticide for the control of rice leafhoppers, planthoppers, codling moth, citrus mealybug, onion thrips, fruit flies, bollworms, and aphids. +" A +31200 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)OP(=S)(OC)OC)[N+](=O)[O-] +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate insecticide that has been used since 1959 to control insects on rice, cereals, fruits, vegetables, stored grains, cotton, to control insects in forests and for fly, mosquito, and cockroach control in public health programs. +Option B: It is an insecticide for the control of rice leafhoppers, planthoppers, codling moth, citrus mealybug, onion thrips, fruit flies, bollworms, and aphids. +Option C: It is an alpha-cyano-3-phenoxyphenyl pyrethroid insecticide used in the control of ectoparasites on cattle, sheep, goats, horses, and dogs. +Option D: It is an organophosphate, household and public health insecticide designed to control cockroaches, flies, ants, ticks, moths, fleas and mosquitoes on contact. +" A +2912 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is a pyrethroid insecticide. +Option B: It is a synthetic pyrethroid insecticide. +Option C: It is a synthetic pyrethroid primarily used as an insecticide. +Option D: It is a pyrethroid ether insecticide. +" C +3082 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC(=O)CSP(=S)(OC)OC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an insecticide and acaricide effective against thrips, mites, aphids, and leafhoppers. +Option B: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option C: It is a contact and systemic organophosphate insecticide effective against a broad range of insects and mites when applied on a wide range of crops. +Option D: It is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. +" C +91655 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)OC(C(Cl)(Cl)Cl)Cl +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests. +Option B: It is used as an insecticide and immobilizing agent for birds, acaricide and molluscicide. +Option C: It is an organophosphate acetylcholinesterase inhibitor used as an insecticide. +Option D: It is a potent acetylcholinesterase-inhibiting insecticide. +" C +17517 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C1=CC=CC=C1OC(=O)NC +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an agricultural insecticide used on rice, cocoa, sugar cane, vegetables and other crops. +Option B: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option C: It is an agricultural insecticide, particularly for rice and tea. +Option D: It is an insecticide used on a variety of crops. +" A +13676 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(CC)SC1=CC=CC=C1 +Question about this molecule: Which kind of insecticide is this molecule? +Option A: It is an agricultural insecticide, particularly for rice and tea. +Option B: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. +Option C: It is an insecticide used on a variety of crops. +Option D: It is primarily used as an insecticide for corn. +" D +6328 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CI +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option B: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +Option C: It can be utilized as an intermediate in the manufacture of some ergoloid medicines. +Option D: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +" A +65110 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O)N)C(=O)N +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. +Option B: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: It is used as a chemical intermediate in the manufacture of dyes, drugs, perfumes, rubber chemicals, tanning agents, and pesticides. +Option D: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +" A +11443 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)N=C=O)N=C=O +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is primarily used as a chemical intermediate in the production of polyurethane products. +Option B: It is used mainly as an intermediate in the manufacture of other products. +Option C: It is presently used only as a chemical intermediate in the production of other chemicals. +Option D: It is used as an intermediate in the production of certain chemicals. +" A +8461 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)[N+](=O)[O-])[N+](=O)[O-] +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the manufacture of polyurethanes. +Option B: It is primarily used as a chemical intermediate in the production of polyurethane products. +Option C: It is used as an intermediate in the production of certain chemicals. +Option D: It is used as an intermediate in the synthesis of a number of chemicals. +" A +6366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=C(Cl)Cl +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in chemical synthesis and to produce polycopolymers. +Option B: It is used as an intermediate in the production of certain chemicals. +Option C: It is used as an intermediate in the synthesis of a number of chemicals. +Option D: It is used mainly as an intermediate in the manufacture of other products. +" A +10039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)=S +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used mainly as an intermediate in the manufacture of other products. +Option B: It is used as an intermediate in organic compound synthesis. +Option C: It is used as an intermediate in the synthesis of a number of chemicals. +Option D: It is used as an intermediate in the production of certain chemicals. +" B +949 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1=CC=CC=C1 +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used mainly as an intermediate in the manufacture of other products. +Option B: It is used as an intermediate in the production of certain chemicals. +Option C: It is used as an intermediate in the manufacture of dyes and other substances. +Option D: It is used as an intermediate in the synthesis of a number of chemicals. +" C +5641 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)N +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used mainly as an intermediate in the manufacture of other products. +Option B: It is used as an intermediate in the production of certain chemicals. +Option C: It is used as an intermediate in the synthesis of a number of chemicals. +Option D: It is used as an intermediate in the manufacture of dyes and other substances. +" C +1031 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCO +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the synthesis of a number of chemicals. +Option B: It is used as an intermediate in the production of certain chemicals. +Option C: It is used as a solvent and chemical intermediate. +Option D: It is presently used only as a chemical intermediate in the production of other chemicals. +" C +5192 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCCCC(=O)O)CCCC(=O)O +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the synthesis of a number of chemicals. +Option B: It is used as an intermediate in the production of certain chemicals. +Option C: It is used mainly as an intermediate in the manufacture of other products. +Option D: It is used as an intermediate for aromatics, antiseptics, and painting materials. +" D +6574 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(Cl)Cl)Cl +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option B: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option C: It is used as a solvent and as an intermediate in the production of the chemical, 1,1-dichloroethane. +Option D: It is used as an intermediate in the production of acetic acid, certain esters, and a number of other chemicals. +" C +1727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=CC=C1N +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an avicide, an intermediate, and as a fixer for some textile dyes. +Option B: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option C: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option D: It can be utilized as an intermediate in the manufacture of some ergoloid medicines. +" A +6544 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=O)CC(C1)(C)C +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the synthesis of a number of chemicals. +Option B: It is used as an intermediate in the manufacture of dyes and other substances. +Option C: It is used mainly as an intermediate in the manufacture of other products. +Option D: It is used as an intermediate in the production of certain chemicals. +" D +6354 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CO1 +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as a chemical intermediate in the manufacture of ethylene glycol. +Option B: It is used as a solvent and chemical intermediate. +Option C: It is presently used only as a chemical intermediate in the production of other chemicals. +Option D: It is used as an intermediate in the synthesis of a number of chemicals. +" A +7047 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC=N2 +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used mainly as an intermediate in the manufacture of other products. +Option B: It is used as an intermediate in the synthesis of a number of chemicals. +Option C: It is used as an intermediate in the manufacture of dyes and other substances. +Option D: It is used as an intermediate in the production of certain chemicals. +" A +7847 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC=O +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is primarily used as an intermediate in the synthesis of acrylic acid and as a biocide. +Option B: It is used as an intermediate in the production of certain chemicals. +Option C: It is used as an intermediate in the synthesis of a number of chemicals. +Option D: It is used mainly as an intermediate in the manufacture of other products. +" A +712 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=O +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option B: It can be utilized as an intermediate in the manufacture of some ergoloid medicines. +Option C: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option D: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +" A +177 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC=O +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option B: It is used as an intermediate in the production of acetic acid, certain esters, and a number of other chemicals. +Option C: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option D: It can be utilized as an intermediate in the manufacture of some ergoloid medicines. +" B +6591 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(Cl)Cl)(Cl)Cl +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the synthesis of a number of chemicals. +Option B: It is used as an intermediate in the production of certain chemicals. +Option C: It is presently used only as a chemical intermediate in the production of other chemicals. +Option D: It is used mainly as an intermediate in the manufacture of other products. +" C +6564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CCl)Cl +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option B: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: Today, almost all of it is used as a chemical intermediate to make perchloroethylene and several other related chlorinated chemicals. +Option D: It is used as an intermediate in the production of acetic acid, certain esters, and a number of other chemicals. +" C +6849 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC=C2[N+](=O)[O-] +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option B: It is used as a chemical intermediate in the manufacture of dyes, drugs, perfumes, rubber chemicals, tanning agents, and pesticides. +Option C: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option D: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +" B +1110 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)C(=O)O +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +Option B: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +Option C: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option D: It is used as a chemical intermediate in the manufacture of dyes, drugs, perfumes, rubber chemicals, tanning agents, and pesticides. +" B +14987 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C[C@@H](C=C2[C@H]1CC3=CNC4=CC=CC2=C34)CO +Question about this molecule: How can the molecule be used as a/an intermediate +Option A: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +Option B: It is used mainly to produce resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: It can be utilized as an intermediate in the manufacture of some ergoloid medicines. +Option D: It is used as an intermediate in the manufacture of some pharmaceuticals and pesticides, in methylation processes, and in the field of microscopy. +" C +6100711 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CNC(=S)[S-])NC(=S)[S-].[Zn+2] +Question about this molecule: Which kind of ligand is this molecule? +Option A: It is a minimal ligand of NOD1. +Option B: It is an ethylene bis(dithiocarbamate) anionic ligand. +Option C: It is a bidentate ligand. +Option D: It is a propylene 1,2-bis(dithiocarbamate) anionic ligand. +" D +6567 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CN)N +Question about this molecule: Which kind of ligand is this molecule? +Option A: It is an ethylene bis(dithiocarbamate) anionic ligand. +Option B: It is a cell-permeable ligand. +Option C: It is a minimal ligand of NOD1. +Option D: It is a bidentate ligand. +" D +5284484 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CNC(=S)[S-])NC(=S)[S-].[Zn+2] +Question about this molecule: Which kind of ligand is this molecule? +Option A: It is a bidentate ligand. +Option B: It is a minimal ligand of NOD1. +Option C: It is a propylene 1,2-bis(dithiocarbamate) anionic ligand. +Option D: It is an ethylene bis(dithiocarbamate) anionic ligand. +" D +45480617 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C[C@@H](C(=O)O)N)C[C@H](C(=O)O)NC(=O)CC[C@H](C(=O)O)N +Question about this molecule: Which kind of ligand is this molecule? +Option A: It is a bidentate ligand. +Option B: It is a minimal ligand of NOD1. +Option C: It is a cell-permeable ligand. +Option D: It is an ethylene bis(dithiocarbamate) anionic ligand. +" B +66070 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C.Cl +Question about this molecule: How can the molecule be used as a/an local anaesthetic +Option A: It is used as a local amide-type anaesthetic. +Option B: It is used as a local anaesthetic. +Option C: It is a piperidinecarboxamide-based local anaesthetic. +Option D: It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. +" B +8612 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCOC(=O)C1=C(C=C(C=C1)N)Cl +Question about this molecule: How can the molecule be used as a/an local anaesthetic +Option A: Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders. +Option B: Used as a local anaesthetic, particularly for oral surgery, it has the advantage over lidocaine of constricting blood vessels, so reducing bleeding. +Option C: It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. +Option D: Used as a local anaesthetic (amide caine), it has rapid onset and long action properties, similar to bupivacaine, and is given by injection during surgical procedures and during labour and delivery. +" C +2482 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC(=O)C1=CC=C(C=C1)N +Question about this molecule: How can the molecule be used as a/an local anaesthetic +Option A: It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. +Option B: Used as a local anaesthetic (amide caine), it has rapid onset and long action properties, similar to bupivacaine, and is given by injection during surgical procedures and during labour and delivery. +Option C: Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders. +Option D: Used as a local anaesthetic, particularly for oral surgery, it has the advantage over lidocaine of constricting blood vessels, so reducing bleeding. +" C +441348 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCOC(=O)C1=C(C=C(C=C1)N)Cl.Cl +Question about this molecule: How can the molecule be used as a/an local anaesthetic +Option A: Used as a local anaesthetic, particularly for oral surgery, it has the advantage over lidocaine of constricting blood vessels, so reducing bleeding. +Option B: It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. +Option C: Used as a local anaesthetic (amide caine), it has rapid onset and long action properties, similar to bupivacaine, and is given by injection during surgical procedures and during labour and delivery. +Option D: Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders. +" A +5282419 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl +Question about this molecule: How can the molecule be used as a/an local anaesthetic +Option A: It is used as a local amide-type anaesthetic. +Option B: It is a piperidinecarboxamide-based local anaesthetic. +Option C: It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. +Option D: It is used as a local anaesthetic. +" B +4062 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C +Question about this molecule: How can the molecule be used as a/an local anaesthetic +Option A: It is a piperidinecarboxamide-based local anaesthetic. +Option B: It is used as a local anaesthetic. +Option C: It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. +Option D: It is used as a local amide-type anaesthetic. +" D +37497 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN(CC)C(CC)C(=O)NC1=C(C=CC=C1C)C +Question about this molecule: How can the molecule be used as a/an local anaesthetic +Option A: It is used as its monohydrochloride salt as a local anaesthetic, particularly for oral surgery. +Option B: Its local anaesthetic properties have been used for surface anaesthesia of the skin and mucous membranes, and for relief of pain and itching associated with some anorectal disorders. +Option C: Used as a local anaesthetic, particularly for oral surgery, it has the advantage over lidocaine of constricting blood vessels, so reducing bleeding. +Option D: Used as a local anaesthetic (amide caine), it has rapid onset and long action properties, similar to bupivacaine, and is given by injection during surgical procedures and during labour and delivery. +" D +11443 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)N=C=O)N=C=O +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of acetone and its derivatives and as a solvent. +Option B: Used in the manufacture of materials such as artificial resins. +Option C: It is used in the manufacture of polyurethane. +Option D: It is used in the manufacture of polyurethane and as an industrial strength adhesive. +" C +5359464 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Tl] +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the production of this molecule for the manufacture of vanillin. +Option B: It is used in the manufacture of polyurethane and as an industrial strength adhesive. +Option C: It is used in the manufacture of acetone and its derivatives and as a solvent. +Option D: It has limited use in the manufacture of special glass and for certain medical procedures. +" D +3776 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)O +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of polyurethane and as an industrial strength adhesive. +Option B: It is used in the production of this molecule for the manufacture of vanillin. +Option C: It is used in the manufacture of acetone and its derivatives and as a solvent. +Option D: Used in the manufacture of materials such as artificial resins. +" C +6658 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=C)C(=O)OC +Question about this molecule: How can the molecule be used for manufacture +Option A: Used to manufacture other chemicals and as a fungicide. +Option B: It is used in the manufacture of resins and plastics. +Option C: It can be used as a fragrance, in foods, beverages, and liniments. +Option D: Used in the manufacture of materials such as artificial resins. +" B +7102 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)N +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of dyes. +Option B: It is used to manufacture azo dyes. +Option C: It is primarily used in the manufacture of dyes. +Option D: It is used in the manufacture of synthetic fibers. +" B +853433 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C/C1=CC(=C(C=C1)O)OC +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the production of this molecule for the manufacture of vanillin. +Option B: It is used in the manufacture of polyurethane and as an industrial strength adhesive. +Option C: It is used in the manufacture of acetone and its derivatives and as a solvent. +Option D: Used in the manufacture of materials such as artificial resins. +" A +7000 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC=CC=C1N +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of synthetic fibers. +Option B: It is primarily used in the manufacture of dyes. +Option C: It is used in the manufacture of dyes. +Option D: It is used in the manufacture of resins and plastics. +" C +6324 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC +Question about this molecule: How can the molecule be used for manufacture +Option A: It can be used as a fragrance, in foods, beverages, and liniments. +Option B: Used to manufacture other chemicals and as a fungicide. +Option C: Used in manufacturing other chemicals. +Option D: Used in the manufacture of materials such as artificial resins. +" C +4133 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)C1=CC=CC=C1O +Question about this molecule: How can the molecule be used for manufacture +Option A: Used in the manufacture of materials such as artificial resins. +Option B: It can be used as a fragrance, in foods, beverages, and liniments. +Option C: It is used in the manufacture of polyurethane and as an industrial strength adhesive. +Option D: It is used in the manufacture of acetone and its derivatives and as a solvent. +" B +7570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CC2=CC=C(C=C2)N=C=O)N=C=O +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of acetone and its derivatives and as a solvent. +Option B: It is used in the production of this molecule for the manufacture of vanillin. +Option C: It is used in the manufacture of polyurethane and as an industrial strength adhesive. +Option D: Used in the manufacture of materials such as artificial resins. +" C +5234 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Na+].[Cl-] +Question about this molecule: How can the molecule be used for manufacture +Option A: It can be used as a fragrance, in foods, beverages, and liniments. +Option B: It is used in the manufacture of polyvinyl chloride, plastics, paper pulp, and many other consumer products. +Option C: Used to manufacture other chemicals, especially dyes, photographic chemicals, agricultural chemicals, and others. +Option D: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +" B +7095 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C2=CC=CC=C2 +Question about this molecule: How can the molecule be used for manufacture +Option A: It can be used as a fragrance, in foods, beverages, and liniments. +Option B: Used in the manufacture of materials such as artificial resins. +Option C: Used to manufacture other chemicals and as a fungicide. +Option D: It is used in the manufacture of acetone and its derivatives and as a solvent. +" C +6811 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C(=O)OC2=O +Question about this molecule: How can the molecule be used for manufacture +Option A: Used to manufacture other chemicals and as a fungicide. +Option B: Used in the manufacture of materials such as artificial resins. +Option C: It can be used as a fragrance, in foods, beverages, and liniments. +Option D: It is used in the manufacture of resins and plastics. +" B +7242 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1N +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of resins and plastics. +Option B: It is primarily used in the manufacture of dyes. +Option C: It is used in the manufacture of synthetic fibers. +Option D: It is used in the manufacture of dyes. +" B +1110 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)C(=O)O +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of polyvinyl chloride, plastics, paper pulp, and many other consumer products. +Option B: It can be used as a fragrance, in foods, beverages, and liniments. +Option C: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +Option D: Used to manufacture other chemicals, especially dyes, photographic chemicals, agricultural chemicals, and others. +" C +7416 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)[N+](=O)[O-] +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of acetone and its derivatives and as a solvent. +Option B: Most of the this molecule produced in the United States is used to manufacture a chemical called aniline. +Option C: It is used in the production of this molecule for the manufacture of vanillin. +Option D: It is used in the manufacture of polyurethane and as an industrial strength adhesive. +" B +6115 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)N +Question about this molecule: How can the molecule be used for manufacture +Option A: It can be used as a fragrance, in foods, beverages, and liniments. +Option B: It is used in the manufacture of polyvinyl chloride, plastics, paper pulp, and many other consumer products. +Option C: It is commonly used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. +Option D: Used to manufacture other chemicals, especially dyes, photographic chemicals, agricultural chemicals, and others. +" D +7768 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(=O)NCC1 +Question about this molecule: How can the molecule be used for manufacture +Option A: It is used in the manufacture of synthetic fibers. +Option B: It is used in the manufacture of resins and plastics. +Option C: It is primarily used in the manufacture of dyes. +Option D: It is used in the manufacture of dyes. +" A +107970 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N +Question about this molecule: Which kind of modulator is this molecule? +Option A: It is a sphingosine 1-phosphate receptor modulator. +Option B: It is an estrogen receptor modulator. +Option C: It is a ryanodine receptor modulator. +Option D: It is a tubulin modulator. +" A +100094 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)N +Question about this molecule: How can the molecule be used as a/an modulator +Option A: It can be used as a synthetic dipeptide immunomodulator in the treatment of chronic hepatitis C viral infection. +Option B: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. +Option C: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. +Option D: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. +" A +107970 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N +Question about this molecule: How can the molecule be used as a/an modulator +Option A: It is an orally available immunomodulatory drug used to treat relapsing multiple sclerosis. +Option B: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. +Option C: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. +Option D: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. +" A +5852 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)([C@H](C(=O)O)N)S +Question about this molecule: How can the molecule be used as a/an modulator +Option A: It is a chelating agent used to decrease copper stores in Wilson disease, and also has immunomodulatory activity in rheumatic diseases such as rheumatoid arthritis, scleroderma, and systemic lupus erythematosus. +Option B: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. +Option C: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. +Option D: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. +" A +1018 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=NC(=C1)C(=O)O +Question about this molecule: How can the molecule be used as a/an modulator +Option A: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. +Option B: It acts as an anti-infective and immunomodulator and is produced in approximately 25-50 mg quantities by the body on a daily basis through the breakdown of tryptophan. +Option C: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. +Option D: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. +" B +5284373 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C +Question about this molecule: How can the molecule be used as a/an modulator +Option A: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. +Option B: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. +Option C: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. +Option D: It has immunomodulatory effects and has been studied in the treatment of various immune-mediated diseases. +" B +54684141 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C(\\C#N)/C(=O)NC1=CC=C(C=C1)C(F)(F)F)/O +Question about this molecule: How can the molecule be used as a/an modulator +Option A: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. +Option B: It is an orally available immunomodulatory drug used to treat relapsing multiple sclerosis. +Option C: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. +Option D: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. +" B +5258 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CCCC(=O)[O-].[Na+] +Question about this molecule: How can the molecule be used as a/an orphan drug +Option A: It is an orphan drug used in combination therapy for the treatment of multiple myeloma. +Option B: It is used as an orphan drug to treat urea cycle disorders. +Option C: It is used as an orphan drug to improve walking in adults with multiple sclerosis. +Option D: It is an orphan drug used for the treatment of pulmonary arterial hypertension. +" B +1727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=CC=C1N +Question about this molecule: How can the molecule be used as a/an orphan drug +Option A: It is an orphan drug used in combination therapy for the treatment of multiple myeloma. +Option B: It is an orphan drug used for the treatment of pulmonary arterial hypertension. +Option C: It is used as an orphan drug to improve walking in adults with multiple sclerosis. +Option D: It is used as an orphan drug to treat urea cycle disorders. +" C +25183872 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: B([C@H](CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O +Question about this molecule: How can the molecule be used as a/an orphan drug +Option A: It is used as an orphan drug to treat urea cycle disorders. +Option B: It is used as an orphan drug to improve walking in adults with multiple sclerosis. +Option C: It is an orphan drug used for the treatment of pulmonary arterial hypertension. +Option D: It is an orphan drug used in combination therapy for the treatment of multiple myeloma. +" D +17513 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)C(=O)N +Question about this molecule: Which kind of orphan drug is this molecule? +Option A: It is currently the only drug available for the treatment of N24HSWD. +Option B: It is a drug for the treatment of supranuclear palsy. +Option C: It is a drug for the treatment of B-CLL. +Option D: It is a drug for the treatment of CML. +" C +92974 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1[C@H]([C@@H](C(=O)O)N)O)O)O +Question about this molecule: Which kind of orphan drug is this molecule? +Option A: It is a drug with orphan drug status for crizotinib-resistant tumors. +Option B: It is a therapeutic option for patients with MoCD type A. +Option C: It is a drug for the treatment of supranuclear palsy. +Option D: It is a drug for the treatment of NOH, Parkinson's disease, pure autonomic failure, and multiple system atrophy. +" D +644019 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O +Question about this molecule: Which kind of orphan drug is this molecule? +Option A: It is a drug for the treatment of supranuclear palsy. +Option B: It is a drug for further study in hard to treat conditions. +Option C: It is a drug for the treatment of B-CLL. +Option D: It is a drug for the treatment of CML. +" B +610479 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O +Question about this molecule: Which kind of orphan drug is this molecule? +Option A: It is a drug for the treatment of B-CLL. +Option B: It is a drug for the treatment of supranuclear palsy. +Option C: It is a drug for the treatment of CML. +Option D: It is currently the only drug available for the treatment of N24HSWD. +" B +2268 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=S)(OC)SCN1C(=O)C2=CC=CC=C2N=N1 +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It was used to protect the seeds of onions and sorghum, wheat, and other grains against fungus until 1965. +Option B: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option C: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +Option D: It is used on crops, especially apples, pears, cherries, peaches, almonds, and cotton. +" D +176879 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC(=O)NNC1=C(C=CC(=C1)C2=CC=CC=C2)OC +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used on crops, especially apples, pears, cherries, peaches, almonds, and cotton. +Option B: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +Option C: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option D: It is used for control of mite pests on greenhouse, shadehouse, nursery, field, landscape and interiorscape grown ornamental plants. +" D +7541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)NC2=NC(=NC(=N2)Cl)Cl)Cl +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It was used as a pesticide until 1991. +Option B: It is a general use pesticide. +Option C: It is used on crops. +Option D: It is used as a fumigant and pesticide. +" C +3017 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)OC1=NC(=NC(=C1)C)C(C)C +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option B: It is used on crops, especially apples, pears, cherries, peaches, almonds, and cotton. +Option C: It is used for control of mite pests on greenhouse, shadehouse, nursery, field, landscape and interiorscape grown ornamental plants. +Option D: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +" A +3033674 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used as a fumigant and pesticide. +Option B: It was widely used as a pesticide and wood preservative. +Option C: It is a general use pesticide. +Option D: It was used as a pesticide until 1991. +" C +8370 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)Cl +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It was used to protect the seeds of onions and sorghum, wheat, and other grains against fungus until 1965. +Option B: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option C: It is used on crops, especially apples, pears, cherries, peaches, almonds, and cotton. +Option D: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +" A +38779 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCSP(=O)(OCC)OC1=C(C=C(C=C1)Br)Cl +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option B: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +Option C: It was used as a pesticide on crops like corn and citrus and on home lawns and gardens until 1983. +Option D: It is used widely in cotton fields for insect control. +" D +3118 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=S)(OCC)SCCSCC +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It was used as a pesticide on crops like corn and citrus and on home lawns and gardens until 1983. +Option B: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +Option C: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option D: It is used to control a variety of harmful pests that attack many field and vegetable crops. +" D +7847 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC=O +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used on crops, especially apples, pears, cherries, peaches, almonds, and cotton. +Option B: It was used to protect the seeds of onions and sorghum, wheat, and other grains against fungus until 1965. +Option C: It is used to control algae, weeds, bacteria, and mollusks. +Option D: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +" C +441071 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN2CC3=CCO[C@H]4CC(=O)N5[C@H]6[C@H]4[C@H]3C[C@H]2[C@@]61C7=CC=CC=C75 +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option B: It is used as a pesticide against household pest insects such as mosquitoes, houseflies and cockroaches. +Option C: It is used as a pesticide, particularly for killing small vertebrates such as birds and rodents. +Option D: The pesticide is also active against non-target invertebrates such as sucking insects and spider mites. +" C +10800 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1O)[N+](=O)[O-])[N+](=O)[O-] +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is a general use pesticide. +Option B: It was widely used as a pesticide and wood preservative. +Option C: It is used as a fumigant and pesticide. +Option D: It was used as a pesticide until 1991. +" D +30773 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNC1=NC(=NC(=N1)Cl)NC(C)(C)C#N +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: The pesticide is also active against non-target invertebrates such as sucking insects and spider mites. +Option B: It is used as a pesticide, particularly for killing small vertebrates such as birds and rodents. +Option C: It is used as a pesticide against household pest insects such as mosquitoes, houseflies and cockroaches. +Option D: It was the fourth most widely used synthetic chemical pesticide in U.S. agriculture in the 1990s. +" D +992 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1(=C(C(=C(C(=C1Cl)Cl)Cl)Cl)Cl)O +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It was widely used as a pesticide and wood preservative. +Option B: It was used as a pesticide on crops like corn and citrus and on home lawns and gardens until 1983. +Option C: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option D: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +" A +7855 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC#N +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: A mixture of it and carbon tetrachloride was used as a pesticide in the past; however, all pesticide uses have stopped. +Option B: Although originally marketed as a pesticide, it has since become the most frequently prescribed oral anticoagulant in North America. +Option C: It is registered for control of annual grasses, certain annual broadleaf weeds and sedges in field corn, seed corn, popcorn and soybeans. +Option D: It was used to protect the seeds of onions and sorghum, wheat, and other grains against fungus until 1965. +" A +5372405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCNP(=S)(OC)O/C(=C/C(=O)OC(C)C)/C +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used as a fumigant and pesticide. +Option B: It was used as a pesticide until 1991. +Option C: It is a general use pesticide. +Option D: It was widely used as a pesticide and wood preservative. +" C +31070 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(NC(C)C)OC1=CC(=C(C=C1)SC)C +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option B: It is used as a pesticide, particularly for killing small vertebrates such as birds and rodents. +Option C: The pesticide is also active against non-target invertebrates such as sucking insects and spider mites. +Option D: It is used as a pesticide against household pest insects such as mosquitoes, houseflies and cockroaches. +" C +54678486 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is registered for control of annual grasses, certain annual broadleaf weeds and sedges in field corn, seed corn, popcorn and soybeans. +Option B: Although originally marketed as a pesticide, it has since become the most frequently prescribed oral anticoagulant in North America. +Option C: It was used to protect the seeds of onions and sorghum, wheat, and other grains against fungus until 1965. +Option D: A mixture of it and carbon tetrachloride was used as a pesticide in the past; however, all pesticide uses have stopped. +" B +91744 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CSC(=C1N(C(C)COC)C(=O)CCl)C +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is registered for control of annual grasses, certain annual broadleaf weeds and sedges in field corn, seed corn, popcorn and soybeans. +Option B: It was used to protect the seeds of onions and sorghum, wheat, and other grains against fungus until 1965. +Option C: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option D: It is used on crops, especially apples, pears, cherries, peaches, almonds, and cotton. +" A +9570071 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(/C=N/OC(=O)NC)SC +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: Although originally marketed as a pesticide, it has since become the most frequently prescribed oral anticoagulant in North America. +Option B: It was the fourth most widely used synthetic chemical pesticide in U.S. agriculture in the 1990s. +Option C: A mixture of it and carbon tetrachloride was used as a pesticide in the past; however, all pesticide uses have stopped. +Option D: It was one of the 'dirty dozen' pesticides that the environmental group Pesticide Action Network North America targeted in 1985. +" D +7839 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CBr)Br +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is used for control of mite pests on greenhouse, shadehouse, nursery, field, landscape and interiorscape grown ornamental plants. +Option B: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops. +Option C: It is used on crops, especially apples, pears, cherries, peaches, almonds, and cotton. +Option D: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops. +" D +6323 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CBr +Question about this molecule: How can the molecule be used as a/an pesticide +Option A: It is a general use pesticide. +Option B: It is used as a fumigant and pesticide. +Option C: It was used as a pesticide until 1991. +Option D: It was widely used as a pesticide and wood preservative. +" B +2477 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4 +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. +Option B: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option C: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option D: It has potential therapeutic use in depression and cognitive impairment via promoting neurogenesis. +" D +6013 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)CC[C@]34C +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option B: It is the basis of using exogenous this molecule as a male contraceptive. +Option C: It has been studied for possible use in heating spacecraft. +Option D: It is possibly effective against infantile spasm. +" B +98888 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN1CCNCCN +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. +Option B: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option C: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option D: It has potential therapeutic use in depression and cognitive impairment via promoting neurogenesis. +" B +6112 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CSS[C@@H]1CCCCC(=O)O +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. +Option B: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option C: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option D: It can be used in diabetes to increase cellular uptake of glucose by recruiting the glucose transporter GLUT4 to the cell membrane. +" D +68406 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCCCCCCCO +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. +Option B: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option C: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option D: It has potential therapeutic use in depression and cognitive impairment via promoting neurogenesis. +" B +6518 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(CO[N+](=O)[O-])(CO[N+](=O)[O-])CO[N+](=O)[O-])O[N+](=O)[O-] +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. +Option B: It was studied for potential benefits in chronic ischemic heart failure patients. +Option C: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option D: It has potential therapeutic use in depression and cognitive impairment via promoting neurogenesis. +" B +802 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C(=CN2)CC(=O)O +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option B: It could be used as the basis for targeted cancer therapy involving antibody-, polymer-, or gene-directed approaches. +Option C: It requires follow-up clinical trials to validate its potential therapy against SARS-CoV-2. +Option D: It is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19. +" B +213039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)CN(C[C@H]([C@H](CC1=CC=CC=C1)NC(=O)O[C@H]2CO[C@@H]3[C@H]2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19. +Option B: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option C: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. +Option D: It requires follow-up clinical trials to validate its potential therapy against SARS-CoV-2. +" A +27400 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1 +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It requires follow-up clinical trials to validate its potential therapy against SARS-CoV-2. +Option B: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option C: It has potential therapeutic use in depression and cognitive impairment via promoting neurogenesis. +Option D: It has potential antidepressant effects, independent of its antimigraine action. +" D +41693 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CS3)COC +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option B: It requires follow-up clinical trials to validate its potential therapy against SARS-CoV-2. +Option C: It is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19. +Option D: Consideration may be made in the future for its use in the US military in cases where analgesia is required immediately. +" D +6328544 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [210Po] +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It has been studied for possible use in heating spacecraft. +Option B: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. +Option C: It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. +Option D: It is possibly effective against infantile spasm. +" A +936 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CN=C1)C(=O)N +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It could be used as the basis for targeted cancer therapy involving antibody-, polymer-, or gene-directed approaches. +Option B: It is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19. +Option C: It requires follow-up clinical trials to validate its potential therapy against SARS-CoV-2. +Option D: It is used in the prevention and/or cure of blacktongue and pellagra. +" D +39186 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC +Question about this molecule: What is the right potential therapeutic use information about this molecule? +Option A: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS). +Option B: It is used clinically as an antihypertensive, anti-arrhythmic, and as an anti-anginal agent for the management of cardiovascular conditions such as hypertension, chronic stable angina, atrial fibrillation, atrial flutter. +Option C: It is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19. +Option D: It requires follow-up clinical trials to validate its potential therapy against SARS-CoV-2. +" B +16684434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[Hg]SC1=CC=CC=C1C(=O)[O-].[Na+] +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. +Option B: It can be used as a preservative in foods, antiseptics, medicines, and cosmetics. +Option C: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option D: It can be used as a preservative in cosmetics, vaccines, and pharmaceuticals. +" A +1732 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=CC(=C1)O)Cl +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative and antibacterial agent in livestock feed. +Option B: It can be used as a preservative in paints and inks. +Option C: It can be used as a preservative in glaucoma medications. +Option D: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +" B +31236 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)OCCO +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option B: It can be used as a preservative in foods, antiseptics, medicines, and cosmetics. +Option C: It can be used as a preservative in cosmetics, vaccines, and pharmaceuticals. +Option D: It can be used as a preservative in cosmetics and industrial substances. +" C +702 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCO +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in glaucoma medications. +Option B: It can be used as a preservative in cosmetics and industrial substances. +Option C: It can be used as a preservative and antibacterial agent in livestock feed. +Option D: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +" D +5282226 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)OC(=O)CCC/C=C\\C[C@H]1[C@H](C[C@H]([C@@H]1/C=C/[C@H](COC2=CC=CC(=C2)C(F)(F)F)O)O)O +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in glaucoma medications. +Option B: It can be used as a preservative and antibacterial agent in livestock feed. +Option C: It can be used as a preservative in cosmetics and industrial substances. +Option D: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +" A +712 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=O +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option B: It can be used as a preservative in foods, antiseptics, medicines, and cosmetics. +Option C: It can be used as a preservative in cosmetics, vaccines, and pharmaceuticals. +Option D: It can be used as a preservative in cosmetics and industrial substances. +" B +61948 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(CBr)(C#N)Br)C#N +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option B: It can be used as a preservative in cosmetics and industrial substances. +Option C: It can be used as a preservative and antibacterial agent in livestock feed. +Option D: It can be used as a preservative in personal hygiene and industrial products. +" D +23668193 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: N(=O)[O-].[Na+] +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option B: It can be used as a preservative in meats and fish. +Option C: It can be used as a preservative in paints and inks. +Option D: It can be used as a preservative for foodstuffs. +" B +643460 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C/C=C/C(=O)O +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option B: It can be used as a preservative for foodstuffs. +Option C: It can be used as a preservative and antibacterial agent in livestock feed. +Option D: It can be used as a preservative in glaucoma medications. +" B +8434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C1=CC=C(C=C1)O +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option B: It can be used as a preservative and antibacterial agent in livestock feed. +Option C: It can be used as a preservative with antibacterial and antifungal properties. +Option D: It can be used as an antimicrobial agent and preservative. +" D +33344 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=O)C=C(S1)Cl +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative in glaucoma medications. +Option B: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option C: It can be used as a preservative with antibacterial and antifungal properties. +Option D: It can be used as a preservative and antibacterial agent in livestock feed. +" C +284 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)O +Question about this molecule: How can the molecule be used as a/an preservative +Option A: It can be used as a preservative and antibacterial agent in livestock feed. +Option B: It can be used as a preservative in cosmetics and industrial substances. +Option C: It can be used as a preservative in pharmaceutical preparations and alcoholic beverages. +Option D: It can be used as a preservative in glaucoma medications. +" A +449381 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N)C(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. +Option B: It is a prodrug for azilsartan, used for the treatment of hypertension. +Option C: It is a prodrug used for treatment of hypertension. +Option D: It is the corresponding ethyl ester prodrug, oseltamivir, to slow the spread of influenza. +" D +104807 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CN)CNCCS +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy. +Option B: It is a prodrug for the free thiol, WR-1065, used as a cytoprotectant in cancer chemotherapy and radiotherapy. +Option C: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option D: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +" A +464205 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. +Option B: It is the 1-ethoxycarbonyloxyethyl ester of ampicillin, a semi-synthetic, microbiologically inactive prodrug of ampicillin. +Option C: It is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin, a prodrug of ampicillin. +Option D: It is the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug used in combination therapy for the treatment of HIV infection. +" D +441397 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)OC(C)OC(=O)[C@H]1C(S[C@H]2N1C(=O)[C@H]2NC(=O)[C@@H](C3=CC=CC=C3)N)(C)C +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is the 1-ethoxycarbonyloxyethyl ester of ampicillin, a semi-synthetic, microbiologically inactive prodrug of ampicillin. +Option B: It is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin, a prodrug of ampicillin. +Option C: It is a prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. +Option D: It is the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug used in combination therapy for the treatment of HIV infection. +" A +135398748 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of dextrorphan, used as an antitussive drug for suppressing cough. +Option B: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option C: It is a prodrug, famciclovir, used for oral administration as an antiviral drug. +Option D: It is a prodrug for melagatran, the first orally available direct thrombin inhibitor brought to market as an anticoagulant. +" C +16574 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C(=O)NC(=O)C=N2)OC(=O)C)OC(=O)C +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for azilsartan, used for the treatment of hypertension. +Option B: It is a prodrug used for treatment of hypertension. +Option C: It is a prodrug for aripiprazole, used for treatment of schizophrenia. +Option D: It is a prodrug for 6-azauridine, used for treatment of psoriasis. +" D +2141 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CN)CNCCSP(=O)(O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy. +Option B: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option C: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option D: It is a prodrug for the free thiol, WR-1065, used as a cytoprotectant in cancer chemotherapy and radiotherapy. +" D +9852981 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCO/N=C(/C1=NSC(=N1)NP(=O)(O)O)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C=C5)C)C(=O)[O-] +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug used for the treatment of adults with acute bacterial skin and skin structure infections. +Option B: It is a prodrug for tazarotenic acid, used for the treatment of psoriasis, acne, and sun-damaged skin. +Option C: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option D: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +" A +72078 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)COP(=O)(O)O)O)CCC4=CC(=O)C=C[C@]34C)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for prednisolone, activated in vivo by phosphatases. +Option B: It is a prodrug for hycanthone. +Option C: It is a prodrug for noradrenalone. +Option D: It is a prodrug for enalaprilat. +" A +60838 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7 +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug converted via hydrolysis to its active metabolite, SN-38, which is ~1000 times more active. +Option B: It is the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy. +Option C: It is a prodrug for the free thiol, WR-1065, used as a cytoprotectant in cancer chemotherapy and radiotherapy. +Option D: The parent acid, loxoprofen, is a prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration. +" A +9884642 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OCCCCO[N+](=O)[O-] +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. +Option B: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option C: It is metabolised to naproxen and a nitric oxide donating moiety, effective in treatment of osteoarthritis. +Option D: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +" C +3105 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option B: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option C: It is a synthetic analogue of prostaglandin F2alpha, used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. +Option D: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. +" D +153970 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCC(=O)NC1=NC(=O)N(C=C1)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)C#N +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for quinaprilat hydrochloride used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. +Option B: It is the prodrug of CNDAC and is currently in clinical development for the treatment of acute myeloid leukemia (AML). +Option C: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option D: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +" B +5284527 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)[C@@H](C4=CC=CC=C4)OC=O)SC2)C(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is used as its dihydrochloride salt as a prodrug for cefotiam. +Option B: It is used (as the sodium salt) as a prodrug for cefamandole. +Option C: It is a prodrug, famciclovir, used for oral administration as an antiviral drug. +Option D: It is a prodrug for melagatran, the first orally available direct thrombin inhibitor brought to market as an anticoagulant. +" B +9576916 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)C[C@@H]1C[C@H](NC1=O)COC2=CC=C(C=C2)C3=CC=C(C=C3)/C(=N/C(=O)OC)/N +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for melagatran, the first orally available direct thrombin inhibitor brought to market as an anticoagulant. +Option B: It is a prodrug of dextrorphan, used as an antitussive drug for suppressing cough. +Option C: It is an orally active prodrug of fradafiban, a figrinogen receptor antagonist. +Option D: It is a prodrug, famciclovir, used for oral administration as an antiviral drug. +" C +45375808 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a nucleotide conjugate used in combination with ledipasvir for the treatment of chronic hepatitis C genotype 1 infection. +Option B: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option C: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option D: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. +" A +5381 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C1=CN=C(C=C1)C#CC2=CC3=C(C=C2)SCCC3(C)C +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option B: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option C: It is a prodrug used for the treatment of adults with acute bacterial skin and skin structure infections. +Option D: It is a prodrug for tazarotenic acid, used for the treatment of psoriasis, acne, and sun-damaged skin. +" D +3388 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCC(=O)OCCN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of dopamine. +Option B: It is the prodrug of fluphenazine. +Option C: It is a prodrug of morphine. +Option D: It is a prodrug of adrenaline. +" B +1548887 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC\\1=C(C2=C(/C1=C\\C3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of adrenaline. +Option B: It is a prodrug of morphine. +Option C: It is a prodrug for the corresponding sulfide. +Option D: It is a prodrug for tedizolid. +" C +3011155 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=NC(=NC2=C1N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of 9-beta-D-arabinofuranosylguanine. +Option B: It is a prodrug of morphine. +Option C: It is a prodrug of adrenaline. +Option D: It is a prodrug of gabapentin. +" A +9883933 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C(=O)OC(C)OC(=O)NCC1(CCCCC1)CC(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of adrenaline. +Option B: It is a prodrug of gabapentin. +Option C: It is the prodrug for gabapentin. +Option D: It is a prodrug of morphine. +" C +5258 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CCCC(=O)[O-].[Na+] +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for phenylacetate. +Option B: It is a prodrug for imidaprilat. +Option C: It is a prodrug for phenylbutazone. +Option D: It is a prodrug for enalaprilat. +" A +2136 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for amfenac. +Option B: It is a prodrug of amfenac. +Option C: It is a prodrug for enalaprilat. +Option D: It is a prodrug for imidaprilat. +" B +25051 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)OC2=NC1=N +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. +Option B: It is metabolised to the antineoplastic agent cytarabine, so is used to maintain a more constant antineoplastic action. +Option C: It is a synthetic analogue of prostaglandin F2alpha, used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. +Option D: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +" B +23674745 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC=C(C=C1)CC2CCCC2=O)C(=O)[O-].O.O.[Na+] +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for the free thiol, WR-1065, used as a cytoprotectant in cancer chemotherapy and radiotherapy. +Option B: It is the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy. +Option C: The parent acid, loxoprofen, is a prodrug that is rapidly converted into its active trans-alcohol metabolite following oral administration. +Option D: It is a prodrug converted via hydrolysis to its active metabolite, SN-38, which is ~1000 times more active. +" C +167305 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)[O-].[OH-].[K+].[K+] +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug used for the management of anxiety disorders, for the short-term relief of anxiety, as adjunctive therapy in the management of epilepsy, and for the symptomatic relief of acute alcohol withdrawal. +Option B: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option C: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option D: It is a prodrug for quinaprilat hydrochloride used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. +" A +11711114 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N.Cl +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for aripiprazole, used for treatment of schizophrenia. +Option B: It is a prodrug used for treatment of HIV. +Option C: It is a prodrug used for treatment of hypertension. +Option D: It is a prodrug for azilsartan, used for the treatment of hypertension. +" B +54891 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O.Cl +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +Option B: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option C: It is a prodrug for quinaprilat hydrochloride used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. +Option D: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. +" C +5311100 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/[C@H](COC2=CC=CC(=C2)C(F)(F)F)O)C/C=C\\CCCC(=O)O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. +Option B: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option C: It is a synthetic analogue of prostaglandin F2alpha, used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. +Option D: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +" C +62956 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCC(CC1)[C@@H]2C[C@H](N(C2)C(=O)CP(=O)(CCCCC3=CC=CC=C3)O)C(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a synthetic analogue of prostaglandin F2alpha, used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. +Option B: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. +Option C: It is a phosphinate ester pro-drug fosinopril used for treatment of hypertension and chronic heart failure. +Option D: It is a prodrug for quinaprilat hydrochloride used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. +" C +20058 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=O)NC2=O)OC(=O)C)OC(=O)C +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. +Option B: It is a prodrug for quinaprilat hydrochloride used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure. +Option C: It is a prodrug used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. +Option D: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. +" C +8064 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCO)CO +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for hycanthone. +Option B: It is a prodrug for noradrenalone. +Option C: It is a prodrug for prednisolone, activated in vivo by phosphatases. +Option D: It is a prodrug for oxolane (also known as tetrahydrofuran or THF). +" D +9870843 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(SC=N1)/C=C\\C2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\\OC)/C4=CSC(=N4)N)SC2)C(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is the 1-ethoxycarbonyloxyethyl ester of ampicillin, a semi-synthetic, microbiologically inactive prodrug of ampicillin. +Option B: It is the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug used in combination therapy for the treatment of HIV infection. +Option C: It is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin, a prodrug of ampicillin. +Option D: It is a pivaloyloxymethyl ester prodrug. +" D +5362 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC1(C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)COC(=O)CCC(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for phenylbutazone. +Option B: It is a prodrug for enalaprilat. +Option C: It is a prodrug for imidaprilat. +Option D: It is a prodrug for phenylacetate. +" A +24830990 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(SCC(S1)(C(=O)O)O)(C(=O)O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for 3-mercaptopyruvic acid. +Option B: It is a prodrug for phenylacetate. +Option C: It is a prodrug for enalaprilat. +Option D: It is a prodrug of mycophenolic acid. +" A +92974 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1[C@H]([C@@H](C(=O)O)N)O)O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for zofenoprilat. +Option B: It is a prodrug for enalaprilat. +Option C: It is a prodrug for noradrenalone. +Option D: It is a prodrug for imidaprilat. +" C +10180 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCNC1=C2C(=C(C=C1)C)SC3=CC=CC=C3C2=O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for imidaprilat. +Option B: It is a prodrug for enalaprilat. +Option C: It is a prodrug for hycanthone. +Option D: It is a prodrug for noradrenalone. +" C +11476460 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4C[C@@H](OC4=O)COP(=O)(O)O)F +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for zofenoprilat. +Option B: It is a prodrug for tedizolid. +Option C: It is a prodrug for imidaprilat. +Option D: It is a prodrug for enalaprilat. +" B +5464343 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2[C@@H](CN(C2=O)C)C(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for phenylacetate. +Option B: It is a prodrug for imidaprilat. +Option C: It is a prodrug for enalaprilat. +Option D: It is a prodrug for zofenoprilat. +" B +5388961 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O.C(=C\\C(=O)O)\\C(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for phenylacetate. +Option B: It is a prodrug for enalaprilat. +Option C: It is a prodrug for zofenoprilat. +Option D: It is a prodrug for imidaprilat. +" B +5463984 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC2=CC=CC=C2N(C(=O)[C@H]1N[C@@H](CCC3=CC=CC=C3)C(=O)O)CC(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of adrenaline. +Option B: It is a prodrug of morphine. +Option C: It is a monoester prodrug. +Option D: It is a prodrug of a platelet inhibitor. +" C +151075 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)N +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for amfenac. +Option B: It is a prodrug of amfenac. +Option C: It is a prodrug for imidaprilat. +Option D: It is a prodrug for enalaprilat. +" A +9883933 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C(=O)OC(C)OC(=O)NCC1(CCCCC1)CC(=O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of adrenaline. +Option B: It is a prodrug of gabapentin. +Option C: It is a prodrug of morphine. +Option D: It is the prodrug for gabapentin. +" B +92974 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1[C@H]([C@@H](C(=O)O)N)O)O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is an orally active prodrug of candoxatrilat. +Option B: It is a prodrug of gabapentin. +Option C: It is an orally available prodrug of norepinephrine. +Option D: It is the prodrug for gabapentin. +" C +3105 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of morphine. +Option B: It is a prodrug of adrenaline. +Option C: It is a prodrug of dopamine. +Option D: It is a prodrug of gabapentin. +" B +60606 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC(=O)[C@H](C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3 +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for aripiprazole, used for treatment of schizophrenia. +Option B: It is a prodrug of a platelet inhibitor. +Option C: It is a prodrug used for treatment of hypertension. +Option D: It is a prodrug used for treatment of HIV. +" B +446541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\\C)/CCC(=O)O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug for enalaprilat. +Option B: It is a prodrug of mycophenolic acid. +Option C: It is a prodrug for phenylacetate. +Option D: It is a prodrug for 3-mercaptopyruvic acid. +" B +6047 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1C[C@@H](C(=O)O)N)O)O +Question about this molecule: Which kind of prodrug is this molecule? +Option A: It is a prodrug of dopamine. +Option B: It is a prodrug of adrenaline. +Option C: It is a prodrug of gabapentin. +Option D: It is a prodrug of morphine. +" A +8255 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=C)C +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of isooctane, a high octane aviation gasoline. +Option B: Used as a solvent, for making other chemicals, and for production of wax from petroleum. +Option C: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +Option D: It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. +" A +280 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)=O +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a solvent. +Option B: It is used to make other chemicals and for dyeing and finishing naturally occurring fibers. +Option C: Used as a refrigerant and in making carbonated beverages. +Option D: It is used to make other chemicals and as a herbicide. +" C +2719 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl +Question about this molecule: How can the molecule be used for production +Option A: It is used to produce the toxic and soluble molecule heme. +Option B: It is used to make other chemicals and as a herbicide. +Option C: It is used to make other chemicals and as a fungicide. +Option D: It is used to make other chemicals and as a solvent. +" A +10967 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(OCCl)Cl +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a solvent. +Option B: The small quantities that are produced are only used in enclosed systems to make other chemicals. +Option C: It is used to make other chemicals and can also be formed in small amounts when chlorine is added to water. +Option D: The small quantities that are produced are used to make other chemicals. +" B +6569 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)C +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals and ranks in the top 20 chemicals for production volume in the United States. +Option B: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +Option C: Used as a solvent, for making other chemicals, and for production of wax from petroleum. +Option D: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +" C +297 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a solvent. +Option B: It is used to make other chemicals and as a fungicide. +Option C: It is used in making other chemicals and as a constituent of the fuel, natural gas. +Option D: It is used to make other chemicals and as a herbicide. +" C +23953 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [SiH4] +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of amorphous silicon. +Option B: It is used in the production of various chemicals such as acrylates in industry. +Option C: It is used in the production of other chemicals. +Option D: It is used in the production of glass. +" A +6359 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(Cl)(Cl)Br +Question about this molecule: How can the molecule be used for production +Option A: The small quantities that are produced are only used in enclosed systems to make other chemicals. +Option B: It is used to make other chemicals and as a solvent. +Option C: It is used to make other chemicals and can also be formed in small amounts when chlorine is added to water. +Option D: The small quantities that are produced are used to make other chemicals. +" D +7845 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC=C +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of 8-hydroxyquinoline, which is a versatile chelating agent and precursor to pesticides. +Option B: It is consumed in the production of aniline, which is a precursor to rubber chemicals, pesticides, dyes, explosives, and pharmaceuticals. +Option C: It is used in the industrial production of 4-vinylcyclohexene via a Diels Alder dimerization reaction. +Option D: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +" C +145068 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [N]=O +Question about this molecule: How can the molecule be used for production +Option A: It is consumed in the production of aniline, which is a precursor to rubber chemicals, pesticides, dyes, explosives, and pharmaceuticals. +Option B: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +Option C: It is used in the production of nitric acid, lacquers, dyes, and other chemicals. +Option D: Used as a solvent, for making other chemicals, and for production of wax from petroleum. +" C +24424 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [O-]S(=O)(=O)[O-].[Zn+2] +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option B: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option C: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +Option D: It is used in the production of rayon, as a feed supplement, and as a fertilizer ingredient. +" D +7367 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(Cl)(Cl)Cl +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a fungicide. +Option B: It is used to make other chemicals and as a herbicide. +Option C: It is used to make other chemicals and as a solvent. +Option D: It is used to make dyes and other chemicals. +" D +674 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNC +Question about this molecule: How can the molecule be used for production +Option A: It is used to make dyes and other chemicals. +Option B: It is used to make other chemicals and as a fungicide. +Option C: It is used to make other chemicals and as a solvent. +Option D: It is used to make other chemicals and as a herbicide. +" C +104838 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O +Question about this molecule: How can the molecule be used for production +Option A: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option B: It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. +Option C: It was first approved by the FDA as the combination product Primaxin marketed by Merck & Co. +Option D: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +" C +6212 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(Cl)(Cl)Cl +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and can also be formed in small amounts when chlorine is added to water. +Option B: It is used to make other chemicals and as a herbicide. +Option C: It is used to make other chemicals and as a solvent. +Option D: It is used to make other chemicals and as a fungicide. +" A +7501 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CC1=CC=CC=C1 +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +Option B: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: It is primarily used in the production of poly this moleculeplastics and resins. +Option D: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +" C +853433 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C=C/C1=CC(=C(C=C1)O)OC +Question about this molecule: How can the molecule be used for production +Option A: It is primarily used in the production of poly this moleculeplastics and resins. +Option B: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: It is used in the production of this molecule for the manufacture of vanillin. +Option D: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +" C +11 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CCl)Cl +Question about this molecule: How can the molecule be used for production +Option A: Used as a solvent, for making other chemicals, and for production of wax from petroleum. +Option B: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +Option C: It is used in the production of vinyl chloride which is used to make a variety of plastic and vinyl products including polyvinyl chloride (PVC) pipes, furniture and automobile upholstery, wall coverings, housewares, and automobile parts. +Option D: It is consumed in the production of aniline, which is a precursor to rubber chemicals, pesticides, dyes, explosives, and pharmaceuticals. +" C +68978 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[As](C)C +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals such as acrylates in industry. +Option B: It is used in the production of other organoarsenic compounds. +Option C: It is used in the production of other chemicals and as a fumigant. +Option D: It is used in the production of other chemicals. +" B +5379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +Option B: It is used in the production of 8-hydroxyquinoline, which is a versatile chelating agent and precursor to pesticides. +Option C: It is used in the production of an eye-drop formulation called Zymar. +Option D: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +" C +9416 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of tretinoin, which is used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. +Option B: It is used in the production of Xyosted - a subcutaneous product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector. +Option C: It is used in the production of florbetapir 18F, which is indicated for positron emission tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline. +Option D: It is used in the production of Fusilev, which has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer. +" B +241 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=CC=C1 +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option B: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option C: It is used in the production of various chemicals and ranks in the top 20 chemicals for production volume in the United States. +Option D: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +" C +7047 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC=N2 +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +Option B: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: It is used in the production of 8-hydroxyquinoline, which is a versatile chelating agent and precursor to pesticides. +Option D: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +" C +7570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CC2=CC=C(C=C2)N=C=O)N=C=O +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of other chemicals and as a fumigant. +Option B: It is used in the production of other chemicals. +Option C: It is used in the production of various chemicals such as acrylates in industry. +Option D: It is used in the production of polyurethane foams. +" D +977 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: O=O +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +Option B: Used as a solvent, for making other chemicals, and for production of wax from petroleum. +Option C: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +Option D: It is used in the production of various chemicals and ranks in the top 20 chemicals for production volume in the United States. +" A +5234 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Na+].[Cl-] +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals such as acrylates in industry. +Option B: It is used in the production of other chemicals and as a fumigant. +Option C: It is used in the production of salt for human consumption. +Option D: It is used in the production of other chemicals. +" C +712 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=O +Question about this molecule: How can the molecule be used for production +Option A: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option B: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: It is used in the production of various chemicals and ranks in the top 20 chemicals for production volume in the United States. +Option D: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +" B +7577 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1CC2=CC=C(C=C2)N)N +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of 4,4'-methylenedianline diisocyanate and other polymeric isocyanates. +Option B: It is used in the production of 8-hydroxyquinoline, which is a versatile chelating agent and precursor to pesticides. +Option C: It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. +Option D: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +" A +5862 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H](C(=O)O)N)S +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of disulphide bond. +Option B: It is used in the production of other chemicals and as a fumigant. +Option C: It is used in the production of other chemicals. +Option D: It is used in the production of various chemicals such as acrylates in industry. +" A +68152 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CO)C(=O)O +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals such as acrylates in industry. +Option B: It is used in the production of other organoarsenic compounds. +Option C: It is used in the production of other chemicals. +Option D: It is used in the production of other chemicals and as a fumigant. +" A +135398559 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H](N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O +Question about this molecule: How can the molecule be used for production +Option A: It is used as a reactive plasticizer or diluent for epoxy resins and in the production of phenethyl alcohol and styrene glycol and its derivatives. +Option B: It is used in the production of tretinoin, which is used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. +Option C: It is used in the production of Fusilev, which has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer. +Option D: It is used in the production of florbetapir 18F, which is indicated for positron emission tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline. +" C +5971 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCN=C=S +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of other chemicals. +Option B: It is used in the production of other chemicals and as a fumigant. +Option C: It is used in the production of various chemicals such as acrylates in industry. +Option D: It is used in the production of other organoarsenic compounds. +" B +7964 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)Cl +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals and ranks in the top 20 chemicals for production volume in the United States. +Option B: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option C: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +Option D: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +" C +5462311 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [B] +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of glass. +Option B: It is used in the production of various chemicals such as acrylates in industry. +Option C: It is used in the production of other chemicals and as a fumigant. +Option D: It is used in the production of other chemicals. +" A +444795 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C +Question about this molecule: How can the molecule be used for production +Option A: It is used as a reactive plasticizer or diluent for epoxy resins and in the production of phenethyl alcohol and styrene glycol and its derivatives. +Option B: It is used in the production of Fusilev, which has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer. +Option C: It is used in the production of florbetapir 18F, which is indicated for positron emission tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline. +Option D: It is used in the production of tretinoin, which is used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. +" D +444266 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=C\\C(=O)O)\\C(=O)O +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a herbicide. +Option B: It is used to make other chemicals and as a fungicide. +Option C: It is used to make other chemicals and for dyeing and finishing naturally occurring fibers. +Option D: It is used to make other chemicals and as a solvent. +" C +996 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)O +Question about this molecule: How can the molecule be used for production +Option A: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option B: It is used in the production of various chemicals and ranks in the top 20 chemicals for production volume in the United States. +Option C: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +Option D: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +" A +6849 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C=CC=C2[N+](=O)[O-] +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a solvent. +Option B: It is used to make dyes and other chemicals. +Option C: It is used to make other chemicals and as a fungicide. +Option D: It is used to make other chemicals and as a herbicide. +" B +6337 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCl +Question about this molecule: How can the molecule be used for production +Option A: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option B: It was commonly used in the production of tetraethyllead (TEL), which is an additive for gasoline. +Option C: It was first approved by the FDA as the combination product Primaxin marketed by Merck & Co. +Option D: It is used in the production of various chemicals and its production in the United States has declined by more than 60% from its peak in 1960. +" B +5987 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: NS(=O)(=O)O +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a solvent. +Option B: It is used to make other chemicals and as a herbicide. +Option C: It is used to make dyes and other chemicals. +Option D: It is used to make other chemicals and as a fungicide. +" C +6422 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)(C(F)(F)F)O +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a solvent. +Option B: It is used to make other chemicals and as a herbicide. +Option C: It is used to make other chemicals and as a fungicide. +Option D: It is used to make dyes and other chemicals. +" A +115015 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H](C(=O)O)N)SS(=O)(=O)O +Question about this molecule: How can the molecule be used for production +Option A: It is used as a reactive plasticizer or diluent for epoxy resins and in the production of phenethyl alcohol and styrene glycol and its derivatives. +Option B: It is used in the production of tretinoin, which is used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. +Option C: It is used in the production of florbetapir 18F, which is indicated for positron emission tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline. +Option D: It is produced by reaction of inorganic sulfite and cystine by a yet unknown pathway and is a very potent NMDA-receptor agonist. +" D +6327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCl +Question about this molecule: How can the molecule be used for production +Option A: It is used to make dyes and other chemicals. +Option B: It is used to make other chemicals and as a fungicide. +Option C: It is used to make other chemicals and as a herbicide. +Option D: It is used to make other chemicals and as a solvent. +" C +7416 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)[N+](=O)[O-] +Question about this molecule: How can the molecule be used for production +Option A: Used as a solvent, for making other chemicals, and for production of wax from petroleum. +Option B: It is used in the production of synthesis gas from coal, for resuscitation, and as an inhalant. +Option C: It is consumed in the production of aniline, which is a precursor to rubber chemicals, pesticides, dyes, explosives, and pharmaceuticals. +Option D: It is used in the production of nitric acid, lacquers, dyes, and other chemicals. +" C +12228 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN=C=O +Question about this molecule: How can the molecule be used for production +Option A: It is used to make other chemicals and as a solvent. +Option B: It is used to make other chemicals and as a fungicide. +Option C: It is used to produce carbamate pesticides. +Option D: It is used to make other chemicals and as a herbicide. +" C +7111 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)N)N +Question about this molecule: How can the molecule be used for production +Option A: It is a component of a test for cyanide and also in the production of dyes. +Option B: It is used in the production of various chemicals such as acrylates in industry. +Option C: It is used in the production of other chemicals. +Option D: It is used in the production of amorphous silicon. +" A +7835 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(O1)CCl +Question about this molecule: How can the molecule be used for production +Option A: It is mainly used in the production of epoxy resins. +Option B: It is used in the production of various chemicals such as acrylates in industry. +Option C: It is used in the production of other chemicals. +Option D: It is used in the production of other chemicals and as a fumigant. +" A +12695 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=O)(C(F)(F)F)C(F)(F)F +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals such as acrylates in industry. +Option B: It is used in the production of other chemicals. +Option C: It is used in the production of other organoarsenic compounds. +Option D: It is used in the production of other chemicals and as a fumigant. +" B +6623 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)O +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of various chemicals such as acrylates in industry. +Option B: It is used in the production of other chemicals. +Option C: It is an important monomer in the production of polycarbonate. +Option D: It is used in the production of polyurethane foams. +" C +931 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C=CC=CC2=C1 +Question about this molecule: How can the molecule be used for production +Option A: It is used in the production of other chemicals. +Option B: It is used in the production of glass. +Option C: It is used in the production of phthalic anhydride. +Option D: It is used in the production of amorphous silicon. +" C +999 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CC(=O)O +Question about this molecule: How can the molecule be used for production +Option A: It is used primarily in the production of phenolic resins and in the manufacture of nylon and other synthetic fibers. +Option B: It is used in the production of resins used in particleboard products and as an intermediate in the synthesis of other chemicals. +Option C: It is used in the illicit production of phenylacetone. +Option D: It is used in the production of 8-hydroxyquinoline, which is a versatile chelating agent and precursor to pesticides. +" C +3301 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CN)N +Question about this molecule: How can the molecule be used for production +Option A: It is used to make dyes and other chemicals. +Option B: It is used to make other chemicals and as a herbicide. +Option C: It is used to make other chemicals and as a fungicide. +Option D: It is used to make other chemicals and as a solvent. +" C +24814 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: Cl[Sb](Cl)Cl +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins. +Option B: It is a reagent used in molecular biology as an oxidizing agent. +Option C: It is a reagent for detecting vitamin A and related carotenoids. +Option D: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +" C +2762682 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C1=CC=CC=C1C2=C3C=CC(=[N+](C)C)C=C3OC4=C2C=CC(=C4)N(C)C.[O-]Cl(=O)(=O)=O +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +Option B: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins. +Option C: It is a reagent used in molecular biology as an oxidizing agent. +Option D: It is a cell-permeant, cationic, red-orange fluorescent dye. +" D +10637 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C2C(=C1)C(=CC(=O)C2=O)S(=O)(=O)O +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent for the selective cleavage of tryptophanyl peptide bonds. +Option B: It is a colorimetric reagent. +Option C: It is a reagent used in molecular biology as an oxidizing agent. +Option D: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +" B +7000 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC=CC=C1N +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins. +Option B: It is a chemical intermediate in the synthesis of azo pigments and dyes. +Option C: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +Option D: It is a reagent used in molecular biology as an oxidizing agent. +" B +11984615 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [NH+](=O)[O-].[Cl-] +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +Option B: It is a reagent used in molecular biology as an oxidizing agent. +Option C: It is a nitrating and chlorinating agent in organic synthesis. +Option D: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins. +" C +7732 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=CC=C(C=C1)N +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent used in molecular biology as an oxidizing agent. +Option B: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +Option C: It is a reagent for the selective cleavage of tryptophanyl peptide bonds. +Option D: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins. +" B +2759573 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COCCN1C(=O)C=CC1=O +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins. +Option B: It is a reagent used in molecular biology as an oxidizing agent. +Option C: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +Option D: It is a reagent for the selective cleavage of tryptophanyl peptide bonds. +" A +20689 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(=O)SCC[N+](C)(C)C +Question about this molecule: Which kind of reagent is this molecule? +Option A: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils. +Option B: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins. +Option C: It is a reagent for determination of butyrylcholinesterase activity. +Option D: It is a reagent used in molecular biology as an oxidizing agent. +" C +3520 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(=N)(N)N +Question about this molecule: How can the molecule be used for research +Option A: It is useful in research for the selection of animal cells that express the E. +Option B: It is used in biochemical research. +Option C: It is used as a research tool in protein biochemistry. +Option D: It is used as a protein denaturant in laboratory research. +" D +31423 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC2=C3C(=C1)C=CC4=CC=CC(=C43)C=C2 +Question about this molecule: How can the molecule be used for research +Option A: It is used as a protein denaturant in laboratory research. +Option B: It is used as a research tool in protein biochemistry. +Option C: It is used in biochemical research. +Option D: It is useful in research for the selection of animal cells that express the E. +" C +5585 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=O)OC2=C1C=C3C=C(OC3=C2C)C +Question about this molecule: How can the molecule be used for research +Option A: It is used in contemporary research regarding novel methods to stabilize mesalazine and to decrease inflammatory activity, potentially reducing the risk of colorectal cancer in conditions like ulcerative colitis. +Option B: It can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage. It has been explored for development of antisense oligonucleotides that can be cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair. +Option C: It is used as one of the widely used antitussives and to study the involvement of glutamate receptors in neurotoxicity. +Option D: It has been used to research obesity and energy balance, and exerts some local analgesia effects. +" B +3423265 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+] +Question about this molecule: How can the molecule be used for research +Option A: It is used as a research tool in protein biochemistry. +Option B: It is used as a protein denaturant in laboratory research. +Option C: It is useful in research for the selection of animal cells that express the E. +Option D: It is used in biochemical research. +" A +446541 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\\C)/CCC(=O)O)O +Question about this molecule: How can the molecule be used for research +Option A: It is used in contemporary research regarding novel methods to stabilize mesalazine and to decrease inflammatory activity, potentially reducing the risk of colorectal cancer in conditions like ulcerative colitis. +Option B: It is used as one of the widely used antitussives and to study the involvement of glutamate receptors in neurotoxicity. +Option C: It has been used to research obesity and energy balance, and exerts some local analgesia effects. +Option D: It is useful in research for the selection of animal cells that express the E. +" D +4500 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC(C1=CC=CC=C1)OC2=CC=CC=C2OC +Question about this molecule: How can the molecule be used for research +Option A: It is used as one of the widely used antitussives and to study the involvement of glutamate receptors in neurotoxicity. +Option B: It is useful in research for the selection of animal cells that express the E. +Option C: It is used in contemporary research regarding novel methods to stabilize mesalazine and to decrease inflammatory activity, potentially reducing the risk of colorectal cancer in conditions like ulcerative colitis. +Option D: It has been used to research obesity and energy balance, and exerts some local analgesia effects. +" D +4075 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1N)C(=O)O)O +Question about this molecule: How can the molecule be used for research +Option A: It can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage. It has been explored for development of antisense oligonucleotides that can be cross-linked specifically to a mutant mRNA sequence without affecting normal transcripts differing at even a single base pair. +Option B: It has been used to research obesity and energy balance, and exerts some local analgesia effects. +Option C: It is used in contemporary research regarding novel methods to stabilize mesalazine and to decrease inflammatory activity, potentially reducing the risk of colorectal cancer in conditions like ulcerative colitis. +Option D: It is used as one of the widely used antitussives and to study the involvement of glutamate receptors in neurotoxicity. +" C +4095 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2 +Question about this molecule: What is the right safety concern information about this molecule? +Option A: The risk appears to be highest in patients with current or past substance use disorders. +Option B: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option C: Prolonged use of it may result in dependence. +Option D: It has the capability or risk for eliciting hepatotoxicity in patients. +" C +5486971 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C[C@@H](CC(=O)O)CN +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It has the capability or risk for eliciting hepatotoxicity in patients. +Option B: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option C: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option D: The risk appears to be highest in patients with current or past substance use disorders. +" D +2313 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=N2)OCC(=O)O +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option B: It has the capability or risk for eliciting hepatotoxicity in patients. +Option C: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option D: It is associated with a potential reduction in corneal sensitivity accompanied by an increased risk of superficial punctate keratitis and subjective symptoms of discomfort. +" B +9395 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOP(=O)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-] +Question about this molecule: What is the right safety concern information about this molecule? +Option A: The harms are generally considered to outweigh the small clinical benefit of use of it due to the risk of adverse effects. +Option B: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option C: It is rarely used as an insecticide due to the risk of poisoning to humans and other animals. +Option D: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +" C +5732 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C2=C(N3C=C(C=CC3=N2)C)CC(=O)N(C)C +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option B: It is associated with a potential reduction in corneal sensitivity accompanied by an increased risk of superficial punctate keratitis and subjective symptoms of discomfort. +Option C: It has a low risk of drug withdrawal, drug dependence, and drug tolerance. +Option D: The harms are generally considered to outweigh the small clinical benefit of use of it due to the risk of adverse effects. +" C +65028 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(CC)O[C@@H]1C=C(C[C@@H]([C@H]1NC(=O)C)N)C(=O)OCC +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is associated with a potential reduction in corneal sensitivity accompanied by an increased risk of superficial punctate keratitis and subjective symptoms of discomfort. +Option B: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option C: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option D: The harms are generally considered to outweigh the small clinical benefit of use of it due to the risk of adverse effects. +" D +271 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [Ca+2] +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option B: Long-term deficiency of it can lead to osteoporosis and an increased risk of fractures. +Option C: It is associated with a potential reduction in corneal sensitivity accompanied by an increased risk of superficial punctate keratitis and subjective symptoms of discomfort. +Option D: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +" B +15130 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H](C(C[C@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C +Question about this molecule: What is the right safety concern information about this molecule? +Option A: The harms are generally considered to outweigh the small clinical benefit of use of it due to the risk of adverse effects. +Option B: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option C: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option D: It was withdrawn from use in the European Union due to its high risk of QT interval prolongation. +" D +1548943 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)/C=C/CCCCC(=O)NCC1=CC(=C(C=C1)O)OC +Question about this molecule: What is the right safety concern information about this molecule? +Option A: Patients treated with lorcaserin may have a higher risk of cancer. +Option B: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option C: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option D: Consumers of it were at higher risk for gastric cancer than non-consumers. +" D +2519 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)C +Question about this molecule: What is the right safety concern information about this molecule? +Option A: Consumers of it were at higher risk for gastric cancer than non-consumers. +Option B: Patients treated with lorcaserin may have a higher risk of cancer. +Option C: Pregnant women and chronically ill individuals should exercise restraint in their use of it. +Option D: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +" C +2727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)Cl +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option B: It has the capability or risk for eliciting hepatotoxicity in patients. +Option C: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option D: The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. +" D +3121 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(CCC)C(=O)O +Question about this molecule: What is the right safety concern information about this molecule? +Option A: The risk of venous thromboembolism with oral contraceptives such as this molecule exists but remains lower than the risk of this condition during pregnancy and during the postpartum period. +Option B: It can cross the placental barrier during pregnancy, which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death. +Option C: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option D: Rarely, serious complications may occur in some patients, including hemorrhagic pancreatitis, coagulopathies, bone marrow suppression, VPA-induced hepatotoxicity and encephalopathy. +" D +887 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CO +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option B: It is rarely used as an insecticide due to the risk of poisoning to humans and other animals. +Option C: It may result in an explosion if large quantities are involved in a fire or if the combustible material is finely divided. +Option D: Any accumulation of vapors in confined spaces may explode if ignited. +" D +784 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: OO +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option B: The risk appears to be highest in patients with current or past substance use disorders. +Option C: It can cause spontaneous combustion when it comes in contact with organic material. +Option D: It is rarely used as an insecticide due to the risk of poisoning to humans and other animals. +" C +5505 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)C +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option B: The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. +Option C: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option D: It has the capability or risk for eliciting hepatotoxicity in patients. +" B +3715 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is associated with a potential reduction in corneal sensitivity accompanied by an increased risk of superficial punctate keratitis and subjective symptoms of discomfort. +Option B: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option C: It can cross the placental barrier during pregnancy, which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death. +Option D: The risk of venous thromboembolism with oral contraceptives such as this molecule exists but remains lower than the risk of this condition during pregnancy and during the postpartum period. +" A +23668193 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: N(=O)[O-].[Na+] +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option B: It may result in an explosion if large quantities are involved in a fire or if the combustible material is finely divided. +Option C: Any accumulation of vapors in confined spaces may explode if ignited. +Option D: It is rarely used as an insecticide due to the risk of poisoning to humans and other animals. +" B +5282379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C\\C(=O)O)/C)/C +Question about this molecule: What is the right safety concern information about this molecule? +Option A: The harms are generally considered to outweigh the small clinical benefit of use of it due to the risk of adverse effects. +Option B: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option C: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option D: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +" D +6432 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(F)(F)F)(C(F)(F)F)(F)F +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option B: Asphyxiation may occur because of displacement of oxygen, although the mixture is nonflammable and nontoxic. +Option C: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option D: The harms are generally considered to outweigh the small clinical benefit of use of it due to the risk of adverse effects. +" B +33741 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)OC)O +Question about this molecule: What is the right safety concern information about this molecule? +Option A: The risk of venous thromboembolism with oral contraceptives such as this molecule exists but remains lower than the risk of this condition during pregnancy and during the postpartum period. +Option B: It is associated with a potential reduction in corneal sensitivity accompanied by an increased risk of superficial punctate keratitis and subjective symptoms of discomfort. +Option C: It can cross the placental barrier during pregnancy, which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death. +Option D: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +" D +7111 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)N)N +Question about this molecule: What is the right safety concern information about this molecule? +Option A: Patients treated with lorcaserin may have a higher risk of cancer. +Option B: Occupational exposure to this molecule results in an increased risk of bladder cancer. +Option C: Consumers of it were at higher risk for gastric cancer than non-consumers. +Option D: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +" B +54678486 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +Option B: It can cross the placental barrier during pregnancy, which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death. +Option C: The risk of venous thromboembolism with oral contraceptives such as this molecule exists but remains lower than the risk of this condition during pregnancy and during the postpartum period. +Option D: Rarely, serious complications may occur in some patients, including hemorrhagic pancreatitis, coagulopathies, bone marrow suppression, VPA-induced hepatotoxicity and encephalopathy. +" B +47811 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN1C[C@@H](C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)CSC +Question about this molecule: What is the right safety concern information about this molecule? +Option A: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option B: The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. +Option C: It increased the risk of cardiac valvulopathy. +Option D: It has effects on increased serum potassium levels, and is associated with a risk of producing hyperkalemia. +" C +10100 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)O[C@](CC1=CC=CC=C1)(C2=CC=CC=C2)[C@H](C)CN(C)C +Question about this molecule: What is the right safety concern information about this molecule? +Option A: The harms are generally considered to outweigh the small clinical benefit of use of it due to the risk of adverse effects. +Option B: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death. +Option C: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. +Option D: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action. +" B +10180 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN(CC)CCNC1=C2C(=C(C=C1)C)SC3=CC=CC=C3C2=O +Question about this molecule: What is the right testing information about this molecule? +Option A: Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test. +Option B: Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood or bone marrow. +Option C: Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. +Option D: It is currently being tested as a radiation sensitizer. +" D +2206 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=O)N(N1C)C2=CC=CC=C2 +Question about this molecule: What is the right testing information about this molecule? +Option A: Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test. +Option B: Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. +Option C: Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood or bone marrow. +Option D: It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome. +" B +33344 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C(=O)C=C(S1)Cl +Question about this molecule: What is the right testing information about this molecule? +Option A: Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood or bone marrow. +Option B: Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test. +Option C: Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. +Option D: It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome. +" B +281 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: [C-]#[O+] +Question about this molecule: What is the right testing information about this molecule? +Option A: It is currently being tested as a radiation sensitizer. +Option B: Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood or bone marrow. +Option C: Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. +Option D: The DLCO test is both convenient and simple for the patient to undergo. +" D +119570 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN[C@H]1CCC2=C(C1)SC(=N2)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement). +Option B: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +Option C: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option D: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +" A +2520 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias. +Option B: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option C: It can be used to treat hypertension and angina pectoris. +Option D: It can be used in the therapy of hypertension and angina pectoris. +" A +1548887 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC\\1=C(C2=C(/C1=C\\C3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in the treatment of acute pain and chronic arthritis. +Option B: It is used for the therapy of chronic arthritis. +Option C: It is used in therapy of chronic arthritis. +Option D: It is used predominantly to treat chronic arthritis. +" D +208898 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C)C(=O)C3=CC=C(C=C3)OCCCN(CCCC)CCCC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement). +Option B: It restores the motor disturbances induced by neuroleptics, in particular the hyperkinesia. +Option C: It works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. +Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis. +" C +25154714 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C=C4)C5=CN=C(N5)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as first-line therapy in patients with genotype 3 without cirrhosis and second-line therapy in genotype 3 patients with compensated cirrhosis. +Option B: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +Option C: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role. +Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis. +" A +5291 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5 +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option B: It can lead to complete hematologic responses in patients with CML. +Option C: It provides a new and promising therapy for the treatment of PPD in adult females. +Option D: It can be used as therapy, both oral and intravenous, in human health and disease. +" B +92786 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@H](C4)O)C)C +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is commonly used as a first line therapy in the treatment of hypertension. +Option B: It provides a new and promising therapy for the treatment of PPD in adult females. +Option C: It is used for the treatment of hypertension. +Option D: It is marketed for the treatment of hypertension. +" B +4095 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2 +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used for the treatment of hypertension. +Option B: It is used for the treatment of opioid addiction. +Option C: It is used for the treatment of schizophrenia symptoms. +Option D: It is used in the treatment of schizophrenia in adult patients. +" B +6274 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=C(NC=N1)C[C@@H](C(=O)O)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It provides a new and promising therapy for the treatment of PPD in adult females. +Option B: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. +Option C: It is a useful therapy in all patients with low histamine levels. +Option D: It is commonly used as a first line therapy in the treatment of hypertension. +" C +2833 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +Option B: It interrupts the cycle of monosodium urate crystal deposition in joint tissues and the resultant inflammatory response in patients with gout. +Option C: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +Option D: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role. +" B +5281613 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement). +Option B: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization. +Option C: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. +Option D: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. +" C +446157 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)C1=NC(=NC(=C1/C=C/[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. +Option B: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement). +Option C: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. +Option D: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization. +" A +5950 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)O)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used predominantly to treat chronic arthritis. +Option B: It is expected to make Clostridium difficile associated diarrhea therapy more accessible. +Option C: It may be treated with medical therapy. +Option D: It has helped dissolve kidney stones in experimental animals. +" D +938 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CN=C1)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. +Option B: It is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic. +Option C: It is effective in lowering low density lipoprotein (LDL) cholesterol and raising high density lipoprotein (HDL) cholesterol, which makes this agent of unique value in the therapy of dyslipidemia. +Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +" C +2809 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in the treatment of schizophrenia in adult patients. +Option B: It is effective in the treatment of anxiety. +Option C: It is used for the treatment of hypertension. +Option D: It is used for the treatment of schizophrenia symptoms. +" B +3394 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain. +Option B: It is widely used for therapy of mild-to-moderate pain and arthritis. +Option C: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms. +Option D: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis. +" D +5362119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N(C1)C(=O)[C@H](CCCCN)N[C@@H](CCC2=CC=CC=C2)C(=O)O)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +Option B: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension. +Option C: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option D: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +" D +3658 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option B: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role. +Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +" D +5460875 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(C(=O)[O-])N)C(=O)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +Option B: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +Option D: It is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia. +" D +3039 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COP(=O)(OC)OC=C(Cl)Cl +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as therapy, both oral and intravenous, in human health and disease. +Option B: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option D: It is used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. +" D +3825 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC(=CC=C1)C(=O)C2=CC=CC=C2)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in the treatment of schizophrenia in adult patients. +Option B: It is used widely in other countries in the treatment of acute pain. +Option C: It is used in the treatment of acute pain and chronic arthritis. +Option D: It can be used in the treatment of acute pain and chronic arthritis. +" C +2327 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1CNNC(=O)C(CO)N)O)O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as therapy, both oral and intravenous, in human health and disease. +Option B: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. +Option C: It is used as a therapy for treating Parkinson's disease. +Option D: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases. +" C +179344 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)O[C@H]1CC2=CC=CC=C2N(C3=CC=CC=C13)C(=O)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases. +Option B: It can be used in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents. +Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option D: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. +" D +2519 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)C +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. +Option B: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. +Option C: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement). +Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +" A +5379 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in therapy of chronic arthritis. +Option B: It is used for intravenous therapy. +Option C: It may be treated with medical therapy. +Option D: It is used for the therapy of chronic arthritis. +" B +148124 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It plays a central role in the therapy of many solid tumors including breast and lung cancer. +Option B: It is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia. +Option C: It is used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +Option D: It plays a central role in the therapy of ovarian, breast, and lung cancer. +" A +38409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CSC(=C1)C(=O)C2=C(C(=C(C=C2)OCC(=O)O)Cl)Cl +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is commonly used as a first line therapy in the treatment of hypertension. +Option B: It is marketed for the treatment of hypertension. +Option C: It is used for the treatment of hypertension. +Option D: It is used in the treatment of schizophrenia in adult patients. +" B +2162 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used as an antihypertensive drug. +Option B: It is used as a lipid-lowering drug. +Option C: It is being studied as an investigational drug as part of a strategy to cure HIV infection. +Option D: It is used for the treatment of opioid addiction. +" A +4601 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)C +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement). +Option B: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option C: It restores the motor disturbances induced by neuroleptics, in particular the hyperkinesia. +Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +" C +3121 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCC(CCC)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as first-line therapy in patients with genotype 3 without cirrhosis and second-line therapy in genotype 3 patients with compensated cirrhosis. +Option B: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. +Option C: It is considered to be a drug of first choice and one of the most frequently-prescribed antiepileptic drugs worldwide for the therapy of generalized and focal epilepsies, including special epileptic. +Option D: It is used as second-line therapy in patients who have inadequate response or intolerance to allopurinol, and should be avoided in patients with cardiovascular diseases. +" C +4917 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. +Option B: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +Option C: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement). +Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +" A +977 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: O=O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in therapy of chronic arthritis. +Option B: It is used for the therapy of chronic arthritis. +Option C: It is used predominantly to treat chronic arthritis. +Option D: It may be treated with medical therapy. +" D +4735 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1C(=N)N)OCCCCCOC2=CC=C(C=C2)C(=N)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is expected to make Clostridium difficile associated diarrhea therapy more accessible. +Option B: Therapy requires careful monitoring. +Option C: It has helped dissolve kidney stones in experimental animals. +Option D: It may be treated with medical therapy. +" B +3261 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C2=NN=CN2C3=C(C=C(C=C3)Cl)C(=N1)C4=CC=CC=C4 +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in therapy of chronic arthritis. +Option B: It is used to treat insomnia. +Option C: It is used predominantly to treat chronic arthritis. +Option D: It is used for the therapy of chronic arthritis. +" B +3386 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: Several weeks of therapy may be required before a clinical effect is seen. +Option B: It is a complete course of therapy in a single, 1 hour 1200 mg infusion. +Option C: It is used as a therapy of intermittent claudication and as a means of secondary prevention of stroke. +Option D: It is commonly used as a first line therapy in the treatment of hypertension. +" A +5862 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H](C(=O)O)N)S +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option B: It is excellent for treatment of asthmatics, enabling them to stop theophylline and other medications. +Option C: It can be used in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents. +Option D: It is widely used in the therapy of hypercholesterolemia, usually in combination with other agents. +" B +193653 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C([C@@H](C(=O)O)N)SCC(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the treatment of asthma, rhinitis, and certain skin conditions. +Option B: It alleviates respiratory symptoms and infections by reducing the viscosity of mucus. +Option C: It is excellent for treatment of asthmatics, enabling them to stop theophylline and other medications. +Option D: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +" B +3058754 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=C(C=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)F)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used to treat osteoarthritis in dogs. +Option B: It can be used in the therapy of hypertension and angina pectoris. +Option C: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias. +Option D: It can be used to treat hypertension and angina pectoris. +" A +54892 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC=CC=C3C[C@H]2C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in the treatment of schizophrenia in adult patients. +Option B: It is marketed for the treatment of hypertension. +Option C: It is used for the treatment of hypertension. +Option D: It is commonly used as a first line therapy in the treatment of hypertension. +" D +4409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used for the therapy of chronic arthritis. +Option B: It can be used in the treatment of acute pain and chronic arthritis. +Option C: It is used in therapy of chronic arthritis. +Option D: It is used in the treatment of acute pain and chronic arthritis. +" C +60750 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It plays a central role in the therapy of ovarian, breast, and lung cancer. +Option B: It is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia. +Option C: It plays a central role in the therapy of many solid tumors including breast and lung cancer. +Option D: It is used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer. +" D +5324346 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COCCCC/C(=N\\OCCN)/C1=CC=C(C=C1)C(F)(F)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is most often used to treat obsessive-compulsive disorder. +Option B: It is used to treat various types of seizures stemming from epileptic disorders. +Option C: It is widely used for therapy of mild-to-moderate pain and arthritis. +Option D: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms. +" A +5284583 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@@H](C(=O)N)N1CCCC1=O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. +Option B: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option C: It is used to treat various types of seizures stemming from epileptic disorders. +Option D: It is excellent for treatment of asthmatics, enabling them to stop theophylline and other medications. +" C +4495 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2 +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used in the treatment of acute pain and chronic arthritis. +Option B: It is used in the treatment of acute pain and chronic arthritis. +Option C: It is used in the treatment of schizophrenia in adult patients. +Option D: It is used widely in other countries in the treatment of acute pain. +" D +4021 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=NN(C(=O)C1)C2=CC=CC=C2 +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option B: It is used for therapy of amyotrophic lateral sclerosis. +Option C: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension. +Option D: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +" B +443879 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=C(C=C1)O)[C@H](CCN(C(C)C)C(C)C)C2=CC=CC=C2 +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used in the therapy of hypertension and angina pectoris. +Option B: It is used to treat osteoarthritis in dogs. +Option C: It is used to treat urinary incontinence. +Option D: It can be used to treat hypertension and angina pectoris. +" C +156391 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms. +Option B: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain. +Option C: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis. +Option D: It is widely used for therapy of mild-to-moderate pain and arthritis. +" D +1349907 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=CNC1=S +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as therapy, both oral and intravenous, in human health and disease. +Option B: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option C: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option D: It is considered the first line agent for medical therapy of hyperthyroidism and Graves disease. +" D +5282452 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CC1C2=NC3=CC=CC=C3C(=C2/C=C/[C@H](C[C@H](CC(=O)O)O)O)C4=CC=C(C=C4)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as first-line therapy in pain conditions. +Option B: It is commonly used as a first line therapy in the treatment of hypertension. +Option C: It can be used as first-line options for the treatment of dyslipidemia. +Option D: It is considered first-line options for the treatment of dyslipidemia. +" D +14969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used predominantly to treat chronic arthritis. +Option B: It has helped dissolve kidney stones in experimental animals. +Option C: It is expected to make Clostridium difficile associated diarrhea therapy more accessible. +Option D: It may be treated with medical therapy. +" C +5493444 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is marketed for the treatment of hypertension. +Option B: It is used in the treatment of schizophrenia in adult patients. +Option C: It is commonly used as a first line therapy in the treatment of hypertension. +Option D: It is used for the treatment of hypertension. +" D +6287 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)[C@@H](C(=O)O)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as therapy, both oral and intravenous, in human health and disease. +Option B: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. +Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis. +" A +3342 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC(=CC=C1)OC2=CC=CC=C2)C(=O)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used in the treatment of acute pain and chronic arthritis. +Option B: It is used widely in other countries in the treatment of acute pain. +Option C: It is used in the treatment of schizophrenia in adult patients. +Option D: It is used in the treatment of acute pain and chronic arthritis. +" A +2955 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension. +Option B: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +Option C: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option D: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +" C +441336 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the treatment of asthma, rhinitis, and certain skin conditions. +Option B: It can be used as therapy, both oral and intravenous, in human health and disease. +Option C: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. +Option D: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization. +" A +1983 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NC1=CC=C(C=C1)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is considered first-line options for the treatment of dyslipidemia. +Option B: It can be used as first-line options for the treatment of dyslipidemia. +Option C: It is commonly used as a first line therapy in the treatment of hypertension. +Option D: It can be used as first-line therapy in pain conditions. +" D +3033 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis. +Option B: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms. +Option C: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain. +Option D: It is widely used for therapy of mild-to-moderate pain and arthritis. +" C +3052776 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C#CCN[C@@H]1CCC2=CC=CC=C12 +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents. +Option B: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases. +Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens. +Option D: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy. +" B +2405 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)NCC(COC1=CC=C(C=C1)COCCOC(C)C)O +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option B: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension. +Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. +Option D: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. +" B +60815 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC(=O)OC)C(=O)OC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is widely used for therapy of mild-to-moderate pain and arthritis. +Option B: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis. +Option C: It can be used for pain relief and adjunctive to an anaesthetic during surgery. +Option D: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain. +" C +53232 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[C@H](C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O)C +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as first-line therapy in pain conditions. +Option B: It can be used as first-line options for the treatment of dyslipidemia. +Option C: It is commonly used as a first line therapy in the treatment of hypertension. +Option D: It is considered first-line options for the treatment of dyslipidemia. +" B +39186 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option B: It can be used to treat hypertension and angina pectoris. +Option C: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias. +Option D: It can be used in the therapy of hypertension and angina pectoris. +" D +5215 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis. +Option B: It can be used in the therapy of mild-to-moderate infections due to sensitive organisms. +Option C: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain. +Option D: It is widely used for therapy of mild-to-moderate pain and arthritis. +" B +1615 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(CC1=CC2=C(C=C1)OCO2)NC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension. +Option B: It can be used as a dissociative anesthetic drug with stimulant and hallucinogenic effects. +Option C: It can be used as a widely abused drug classified as a hallucinogen. +Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis. +" C +4485 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It can be used for the therapy of leprosy and dermatitis herpetiformis. +Option B: It can be used in the therapy of hypertension and angina pectoris. +Option C: It is used for treatment of hypertension, angina pectoris and superventricular tachyarrhythmias. +Option D: It can be used to treat hypertension and angina pectoris. +" D +5073 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is commonly used as a first line therapy in the treatment of hypertension. +Option B: It can be used for the treatment of autistic spectrum disorders. +Option C: It is used for the treatment of hypertension. +Option D: It is marketed for the treatment of hypertension. +" B +2662 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F +Question about this molecule: How can the molecule be used for therapeutic use +Option A: It is used predominantly to treat chronic arthritis. +Option B: It is widely used in the therapy of arthritis. +Option C: It is used in therapy of chronic arthritis. +Option D: It is used for the therapy of chronic arthritis. +" B +2997 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3 +Question about this molecule: How can the molecule be used for treatment +Option A: It is used for treatment of gastrointestinal disorders. +Option B: It is used primarily in the treatment of anxiety. +Option C: It can be used for the treatment of major depression. +Option D: It can be used for the treatment of various diseases. +" B +20279 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=C(N=C32)Cl)N)CO)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains. +Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +Option C: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +Option D: It is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia. +" D +3080 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(C(CS)S)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains. +Option B: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery. +Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option D: It is used clinically for the treatment of poisoning by arsenic, mercury, gold, antimony, bismuth, and possibly thallium. +" D +3948 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +Option C: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery. +Option D: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +" C +5311065 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1C[C@H](N(C1)C(=O)[C@@H]2CSSCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N[C@H](CCCN=C(N)N)C(=O)NCC(=O)N +Question about this molecule: How can the molecule be used for treatment +Option A: It is used for the treatment of nocturia due to nocturnal polyuria in adults. +Option B: It is used as a treatment for leishmaniasis. +Option C: It is used in the treatment of giardiasis and cholera. +Option D: It can be used for the treatment of specific soft tissue sarcomas. +" A +1549008 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C#C/C=C/CN(C)CC1=CC=CC2=CC=CC=C21 +Question about this molecule: How can the molecule be used for treatment +Option A: It is used as an Echinocandin Antifungal. +Option B: It is used as an Oxaborole Antifungal. +Option C: It can be used as an Allylamine Antifungal. +Option D: It is used as a Benzylamine Antifungal. +" C +248 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[N+](C)(C)CC(=O)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for the treatment of specific soft tissue sarcomas. +Option B: It is used in the treatment of giardiasis and cholera. +Option C: It is used for the treatment of nocturia due to nocturnal polyuria in adults. +Option D: It is used as a source of hydrochloric acid in the treatment of hypochlorhydria. +" D +2366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC1=CC=CC=N1 +Question about this molecule: How can the molecule be used for treatment +Option A: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +Option B: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option C: It is used for treating symptoms associated with This molecule as a histamine-like antivertigo drug. +Option D: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +" C +16684434 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[Hg]SC1=CC=CC=C1C(=O)[O-].[Na+] +Question about this molecule: How can the molecule be used for treatment +Option A: It is used as an Echinocandin Antifungal. +Option B: It can be used as an antibacterial and antifungal agent. +Option C: It is used as an antiseptic and antifungal agent. +Option D: It can be used as an antifungal antibiotic. +" C +45375808 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H](C(=O)OC(C)C)N[P@](=O)(OC[C@@H]1[C@H]([C@@]([C@@H](O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3 +Question about this molecule: How can the molecule be used for treatment +Option A: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +Option B: It can be used for the treatment of Lennox-Gastaut syndrome and Dravet syndrome. +Option C: It can be used for the treatment of chronic Hepatitis C. +Option D: It is used for the treatment of chronic Hepatitis C as a Direct Acting Antiviral (DAA). +" D +3468 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)C1=CC=C(C=C1)C(=C2C=CC(=[N+](C)C)C=C2)C3=CC=C(C=C3)N(C)C +Question about this molecule: How can the molecule be used for treatment +Option A: It is used for its antibacterial, antifungal, and anthelmintic properties as a mixture of violet rosanilinis. +Option B: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery. +Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option D: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +" A +11499245 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: B1(C2=C(CO1)C=C(C=C2)F)O +Question about this molecule: How can the molecule be used for treatment +Option A: It is used as an Echinocandin Antifungal. +Option B: It is used as a Benzylamine Antifungal. +Option C: It is used as an Oxaborole Antifungal. +Option D: It can be used as an Allylamine Antifungal. +" C +2484 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C)(C)C1=CC=C(C=C1)CN(C)CC2=CC=CC3=CC=CC=C32 +Question about this molecule: How can the molecule be used for treatment +Option A: It is used as an Oxaborole Antifungal. +Option B: It is used as a Benzylamine Antifungal. +Option C: It can be used as an Allylamine Antifungal. +Option D: It is used as an Echinocandin Antifungal. +" B +2519 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN1C=NC2=C1C(=O)N(C(=O)N2C)C +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used as a hallucinogenic drug. +Option B: It can be used as an immunosuppressive and antitumor agent. +Option C: It is used as an antiseptic and antifungal agent. +Option D: It can be used as a psychostimulant drug. +" D +5564 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl +Question about this molecule: How can the molecule be used for treatment +Option A: It is used as an Echinocandin Antifungal. +Option B: It can be used as an antibacterial and antifungal agent. +Option C: It can be used as an antifungal antibiotic. +Option D: It is used as an antiseptic and antifungal agent. +" B +5634 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C=CCCCCCCCCC(=O)O +Question about this molecule: How can the molecule be used for treatment +Option A: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery. +Option B: It can be used to treat skin infections such as athlete's foot and relieve itching, burning, and irritation associated with the skin condition. +Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option D: It can be used for the treatment of sickle cell disease, malaria, and some cancers. +" B +1727 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CN=CC=C1N +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used to help with mobility in these patients. +Option B: It is used for the treatment of migraine headaches. +Option C: It can be used for the treatment of migraine headaches. +Option D: It is used for treatment of gastrointestinal disorders. +" A +20299 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC[N+](CC)(CC)CCC(C1CCCCC1)(C2=CC=CC=C2)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option B: It is used for its antibacterial, antifungal, and anthelmintic properties as a mixture of violet rosanilinis. +Option C: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +Option D: It can be used as an antimuscarinic, anticholinergic drug. +" D +702 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCO +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used as a drug with a depressive effect on the central nervous system. +Option B: It can be used for the treatment of sickle cell disease, malaria, and some cancers. +Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option D: It can be used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. +" A +4781 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3 +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used in the treatment of status epilepticus. +Option B: It should not be employed for the treatment of gouty arthritis. +Option C: It can be used for the treatment of treatment-resistant major depression. +Option D: It is highly effective for the management of the ""positive"" symptoms of schizophrenia. +" B +12620 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCCCCCCCCCCCCCCCCCCO +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for topical treatment for recurrent herpes simplex labialis episodes. +Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +Option C: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +Option D: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +" A +644019 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCCCC1=CC(=C(C(=C1)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +Option C: It can be used for the treatment of Lennox-Gastaut syndrome and Dravet syndrome. +Option D: It can be used for the treatment of sickle cell disease, malaria, and some cancers. +" C +3366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=NC(=O)NC(=C1F)N +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used as a Nucleoside Analog Antifungal. +Option B: It is used as a Benzylamine Antifungal. +Option C: It can be used as an Allylamine Antifungal. +Option D: It is used as an Echinocandin Antifungal. +" A +71158 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(=O)NCCCS(=O)(=O)O +Question about this molecule: How can the molecule be used for treatment +Option A: It is used as a treatment for leishmaniasis. +Option B: It can be used in gynecology. +Option C: It is used in the treatment of giardiasis and cholera. +Option D: It can be used for the maintenance of alcohol abstinence. +" D +5656 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for the treatment of treatment-resistant major depression. +Option B: It can be used for the treatment of severe long-term depression. +Option C: It can be used for the treatment of major depression. +Option D: It can be used for the treatment of various diseases. +" B +175805 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CCCN1CCCC[C@H]1C(=O)NC2=C(C=CC=C2C)C +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used as an aminoamide local anesthetic drug. +Option B: It is used as an antiseptic and antifungal agent. +Option C: It can be used as an antifungal antibiotic. +Option D: It can be used as an antibacterial and antifungal agent. +" A +14969 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@H]1[C@H]([C@@](C[C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=C4C=C5C=C3OC6=C(C=C(C=C6)[C@H]([C@H](C(=O)N[C@H](C(=O)N[C@H]5C(=O)N[C@@H]7C8=CC(=C(C=C8)O)C9=C(C=C(C=C9O)O)[C@H](NC(=O)[C@H]([C@@H](C1=CC(=C(O4)C=C1)Cl)O)NC7=O)C(=O)O)CC(=O)N)NC(=O)[C@@H](CC(C)C)NC)O)Cl)CO)O)O)(C)N)O +Question about this molecule: How can the molecule be used for treatment +Option A: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +Option C: It can be used for the treatment of Clostridium difficile associated diarrhea and enterocolitis caused by Staphylococcus aureus, including methicillin-resistant strains. +Option D: It is used as an antimetabolite antineoplastic drug for the treatment of lymphoid malignancies including hairy-cell leukaemia and chronic lymphocytic leukaemia. +" C +2812 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4 +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option B: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +Option C: It can be used for the treatment of sickle cell disease, malaria, and some cancers. +Option D: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery. +" C +2911 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1CCN(CC1)CCC(C2CCCC2)(C3=CC=CC=C3)O +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for the treatment and management of Parkinson's disease. +Option B: It can be used for the treatment of sickle cell disease, malaria, and some cancers. +Option C: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation. +Option D: It can be used for the treatment of Lennox-Gastaut syndrome and Dravet syndrome. +" A +2206 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC1=CC(=O)N(N1C)C2=CC=CC=C2 +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for the treatment of sickle cell disease, malaria, and some cancers. +Option B: It can be used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. +Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients. +Option D: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery. +" B +47472 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C(=C1)Cl)SC(CCC2=CC=C(C=C2)Cl)CN3C=CN=C3)Cl +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used in the treatment of status epilepticus. +Option B: It is used as a treatment for leishmaniasis. +Option C: It is used in the treatment of giardiasis and cholera. +Option D: It can be used in gynecology. +" D +5284616 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used as an antibacterial and antifungal agent. +Option B: It can be used as an antifungal antibiotic. +Option C: It is used as an antiseptic and antifungal agent. +Option D: It can be used as an immunosuppressive and antitumor agent. +" D +119 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C(CC(=O)O)CN +Question about this molecule: How can the molecule be used for treatment +Option A: It is used as a treatment for leishmaniasis. +Option B: It can be used in the treatment of status epilepticus. +Option C: It is used in the treatment of giardiasis and cholera. +Option D: It can be used in the treatment of epilepsy and bipolar disorder. +" B +182137 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CN[C@@]1(CCCCC1=O)C2=CC=CC=C2Cl +Question about this molecule: How can the molecule be used for treatment +Option A: It can be used for the treatment of treatment-resistant major depression. +Option B: It can be used for the treatment of major depression. +Option C: It can be used for the treatment of various diseases. +Option D: It can be used for the treatment of severe long-term depression. +" A +4189 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl +Question about this molecule: How can the molecule be used for treatment +Option A: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis. +Option B: It is used as a triazole antifungal with a broad spectrum of activity and good safety profile. +Option C: It is used in the prevention and treatment of a variety of fungal infections as an imidazole antifungal agent. +Option D: It can be used as a broad-spectrum azole antifungal with some activity against Gram-positive bacteria. +" D +5371562 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C/C(=C\\C(=O)NC)/OP(=O)(OC)OC +Question about this molecule: What is the right withdrawal information about this molecule? +Option A: It was withdrawn in 2000 due to the risk of hepatotoxicity. +Option B: It was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. +Option C: It was withdrawn from use on potatoes and tomatoes in 1985. +Option D: It was withdrawn from the market by Elan Pharmaceuticals in 2001. +" C +2366 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CNCCC1=CC=CC=N1 +Question about this molecule: What is the right withdrawal information about this molecule? +Option A: It was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. +Option B: It was withdrawn within approximately 5 years of its first approval by the FDA in the 1970s due to a lack of evidence supporting its efficacy. +Option C: It was withdrawn in 1965 because of dissociative hallucinogenic effects that were often disturbing and sometimes severe and prolonged. +Option D: It was withdrawn from Canadian and U.S. markets in October 2010 due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease. +" B +5323 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC +Question about this molecule: What is the right withdrawal information about this molecule? +Option A: It is one of the products that have been withdrawn or removed from the market in the US after being found to be unsafe or not effective. +Option B: It was withdrawn from Canadian and U.S. markets in October 2010 due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease. +Option C: It was withdrawn within approximately 5 years of its first approval by the FDA in the 1970s due to a lack of evidence supporting its efficacy. +Option D: It was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis. +" A +39941 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: CC(C1=CC2=C(C=C1)OC(=N2)C3=CC=C(C=C3)Cl)C(=O)O +Question about this molecule: What is the right withdrawn from market information about this molecule? +Option A: It was withdrawn from the market due to adverse side-effects including liver necrosis, photosensitivity, and carcinogenicity in animals. +Option B: It was withdrawn from the market in 1982 due to links with hepatitis. +Option C: It was withdrawn from the market following its association with cases of Stevens-Johnson syndrome. +Option D: It was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market. +" A +38409 "Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options. +Molecule SMILES: C1=CSC(=C1)C(=O)C2=C(C(=C(C=C2)OCC(=O)O)Cl)Cl +Question about this molecule: What is the right withdrawn from market information about this molecule? +Option A: It was withdrawn from the market following suspicions of carcenogenicity. +Option B: It was withdrawn from the market following its association with cases of Stevens-Johnson syndrome. +Option C: It was withdrawn from the market due to causing severe gastrointestinal bleeding. +Option D: It was withdrawn from the market in 1982 due to links with hepatitis. +" D