CID	Question	Answer
6473883	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]([C@H]2[C@H]([C@H]([C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)N[C@H](O2)COCCOC)C)(C)O
Question about this molecule: What is the right administration information about this molecule?
Option A: It is administered (as the sulfate salt) by intramuscular injection or intravenous infusion for the treatment of severe systemic infections due to sensitive Gram-negative organisms.
Option B: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity.
Option C: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease.
Option D: Administered as enteric coated tablets to protect it from acid catalysed hydrolysis in the stomach, it is used to treat respiratory tract, skin, and soft tissue infections caused by susceptible organisms.
"	D
6957673	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)NC3=CC=C(C=C3)C(=O)O
Question about this molecule: What is the right administration information about this molecule?
Option A: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media.
Option B: It is given by mouth for noninvasive screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
Option C: It is administered by inhalation (generally as the tartrate salt) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease.
Option D: Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity.
"	B
44591583	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
Question about this molecule: Which kind of agent is this molecule?
Option A: It is an antispasmodic and anticholinergic agent used to treat urinary incontinence and overactive bladder syndrome.
Option B: It is a non-steroidal agent efficacious in improving disease severity, reducing the risk of infection, and reducing the signs and symptoms in patients 2 years old and older.
Option C: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome.
Option D: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome.
"	B
60846	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O
Question about this molecule: Which kind of agent is this molecule?
Option A: It is an anticholinergic agent used to treat gastrointestinal conditions such as acid peptic disease and irritable bowel syndrome.
Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension and diabetic nephropathy.
Option C: It is an anticholinergic and antispasmodic agent used to treat urinary incontinence and overactive bladder syndrome.
Option D: It is an angiotensin II receptor blocker used to treat hypertension and reduce cardiovascular mortality after myocardial infarction.
"	D
4440	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CNS(=O)(=O)CCC1=CC2=C(C=C1)NC=C2C3CCN(CC3)C
Question about this molecule: Which kind of agonist is this molecule?
Option A: It is a Serotonin-1b and Serotonin-1d Receptor Agonist.
Option B: It is a gonadotropin releasing hormone (GnRH) agonist.
Option C: It is an Opioid Agonist.
Option D: It is a selective alpha-adrenergic receptor agonist.
"	A
44472635	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C[C@@H](N[C@@H]1CC2=CC=C(C=C2)NC(=O)[C@@H]3CCC4=NC=CC(=O)N34)[C@@H](C5=CC=CC=C5)O
Question about this molecule: Which kind of agonist is this molecule?
Option A: It is a selective alpha-adrenergic receptor agonist.
Option B: It is a beta-3 adrenergic agonist.
Option C: It is a GABA receptor agonist.
Option D: It is a cannabinoid receptor agonist.
"	B
5311501	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C2=C3N1[C@@H](COC3=CC=C2)CN4CCOCC4)C(=O)C5=CC=CC6=CC=CC=C65
Question about this molecule: Which kind of agonist is this molecule?
Option A: It is a cannabinoid receptor agonist.
Option B: It is a beta-3 adrenergic agonist.
Option C: It is a GABA receptor agonist.
Option D: It is a selective alpha-adrenergic receptor agonist.
"	A
5078	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Question about this molecule: Which kind of agonist is this molecule?
Option A: It is a selective alpha-adrenergic receptor agonist.
Option B: It is a Serotonin-1b and Serotonin-1d Receptor Agonist.
Option C: It is a gonadotropin releasing hormone (GnRH) agonist.
Option D: It is an Opioid Agonist.
"	B
25074470	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8
Question about this molecule: Which kind of agonist is this molecule?
Option A: It is a Serotonin-1b and Serotonin-1d Receptor Agonist.
Option B: It is an Opioid Agonist.
Option C: It is a gonadotropin releasing hormone (GnRH) agonist.
Option D: It is a selective alpha-adrenergic receptor agonist.
"	C
2435	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br
Question about this molecule: Which kind of agonist is this molecule?
Option A: It is a selective alpha-adrenergic receptor agonist.
Option B: It is a beta-3 adrenergic agonist.
Option C: It is a GABA receptor agonist.
Option D: It is a cannabinoid receptor agonist.
"	A
60857	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
Question about this molecule: Which kind of agonist is this molecule?
Option A: It is a gonadotropin releasing hormone (GnRH) agonist.
Option B: It is a selective alpha-adrenergic receptor agonist.
Option C: It is an Opioid Agonist.
Option D: It is a Serotonin-1b and Serotonin-1d Receptor Agonist.
"	D
86138	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C(CCC2=CC=C(C=C2)Cl)(CN3C=NC=N3)C#N
Question about this molecule: How can the molecule be used as a/an agricultural chemical
Option A: It is used as an agricultural insecticide and nematocide.
Option B: It is used as a systemic agricultural insecticide, acaricide, and nematocide.
Option C: It is used as an agricultural insecticide, acaricide, bactericide, and fungicide.
Option D: It is used as an agricultural and horticultural fungicide spray.
"	D
9576037	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=NNC(=O)N(C1)/N=C/C2=CN=CC=C2
Question about this molecule: How can the molecule be used as a/an agricultural chemical
Option A: It controls aphids on potatoes and vegetable brassica crops.
Option B: It is used to kill insects on farm crops and in gardens.
Option C: It is used mainly in agriculture to protect field and vegetable crops.
Option D: It is used on corn crops, including popcorn.
"	A
73665	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N2C=CN=C2
Question about this molecule: How can the molecule be used as a/an agricultural chemical
Option A: It is used in agriculture to treat plant diseases like mildew, for water treatment, and as preservatives for wood, leather, and fabrics.
Option B: It is used in agriculture to control insects on citrus trees, cotton, fruit and nut trees, and some vegetables.
Option C: It is sold for use on grapes, potatoes, tomatoes, hops, sugarbeets, and other vegetable crops.
Option D: It is used in seed dressing to prevent fungal diseases of many crops and for the protection of citrus fruits during storage and transport.
"	D
3293	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C
Question about this molecule: How can the molecule be used as a/an agricultural chemical
Option A: It is used as an agricultural insecticide, acaricide, bactericide, and fungicide.
Option B: It is formerly used as an agricultural pesticide/herbicide, now superseded.
Option C: It is used as an agricultural and horticultural fungicide spray.
Option D: It is used as a systemic agricultural insecticide, acaricide, and nematocide.
"	B
3718	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C1=CC=C(C=C1)N2CC3=CC=CC=C3C2=O)C(=O)O
Question about this molecule: Which kind of analgesic is this molecule?
Option A: It has analgesic and anti-inflammatory properties.
Option B: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Option C: It possesses anti-inflammatory, analgesic and antipyretic activity.
Option D: It belongs to the salicylate group of drugs, which are used as analgesic agents for the treatment of mild to moderate pain.
"	A
644073	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O
Question about this molecule: Which kind of analgesic is this molecule?
Option A: It is a sublingually and transdermally available, semisynthetic opioid analgesic, which is used as an analgesic and for management of opioid dependence.
Option B: It is an opioid analgesic derived from morphine and used mainly as an analgesic.
Option C: It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Option D: It is an active ingredient in some pharmaceutical products as a mild analgesic for pain relief by releasing salicylate.
"	A
5311501	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C2=C3N1[C@@H](COC3=CC=C2)CN4CCOCC4)C(=O)C5=CC=CC6=CC=CC=C65
Question about this molecule: Which kind of analgesic is this molecule?
Option A: It is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements.
Option B: The analgesic properties of Tramadol can be attributed to norepinephrine and serotonin reuptake blockade in the CNS, which inhibits pain transmission in the spinal cord.
Option C: It is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist.
Option D: It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain.
"	D
10237	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
Option B: It is a light-sensitive competitive antagonist of GABAA receptors.
Option C: It is a competitive, reversible antagonist of muscarinic receptors.
Option D: It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors.
"	B
8969	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an alpha-adrenergic antagonist.
Option B: It is an adrenergic antagonist.
Option C: It is a selective alpha-1a adrenergic antagonist.
Option D: It is a beta-adrenergic antagonist.
"	A
2799722	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCNC(=O)C(C1)NC(=O)C2=CC=CC=C2NC(=O)C3=CC4=CC=CC=C4S3
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a non-competitive antagonist of tropomyosin receptor kinase B (TrkB).
Option B: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist.
Option C: It is a peroxisome proliferator-activator receptor-delta agonist for the potential treatment of dyslipidemia.
Option D: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
"	A
5312120	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCOC1=CC2=C(C=C1/C(=C/C3=CC=C(C=C3)C(=O)O)/C)C(CCS2(=O)=O)(C)C
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a serotonergic antagonist and a dopaminergic antagonist.
Option B: It is a GABA antagonist and a serotonergic antagonist.
Option C: It is a retinoic acid receptor alpha antagonist.
Option D: It is a neutral retinoic acid receptor (RAR) alpha-selective antagonist.
"	C
208947	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C2CC[C@@H](C(=O)N2C3=CC=CC=C13)CC4=C(NC=N4)C
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a 5-HT2 antagonist.
Option B: It is a glutamate receptor antagonist.
Option C: It is a 5-HT3 and 5-HT4 receptors antagonist.
Option D: It is an antagonist of 5-HT3 receptors.
"	C
21582644	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CCC[C@]([C@@H]1CC[C@@]3([C@@H]2CCC4=COC=C43)C)(C)C(=O)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an estrogen antagonist.
Option B: It is an estrogen receptor antagonist.
Option C: It is an aryl hydrocarbon receptor antagonist.
Option D: It is an androgen antagonist.
"	D
45266503	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[NH+]1[C@@H]2CC[C@H]1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4.CS(=O)(=O)[O-]
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an acetylcholine receptor antagonist.
Option B: It is an orexin receptor antagonist.
Option C: It is an adenosine A1 receptor antagonist.
Option D: It is an aryl hydrocarbon receptor antagonist.
"	A
68552	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC2(CC1)OCC(O2)CN=C(N)N.C1CCC2(CC1)OCC(O2)CN=C(N)N.OS(=O)(=O)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an alpha-adrenergic antagonist.
Option B: It is a beta-adrenergic antagonist.
Option C: It is a selective alpha-1a adrenergic antagonist.
Option D: It is an adrenergic antagonist.
"	D
5074	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(=O)N2C=CSC2=N1)CCN3CCC(=C(C4=CC=C(C=C4)F)C5=CC=C(C=C5)F)CC3
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a potent antagonist for both S1P1 and S1P3 receptors.
Option B: It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor.
Option C: It is a seratonin (5-hydroxytryptamine, 5-HT) antagonist.
Option D: It is a potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor.
"	C
1201549	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1[C@@H]2CC[C@H]1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a GABA antagonist and a serotonergic antagonist.
Option B: It is a H1-receptor antagonist and a muscarinic antagonist.
Option C: It is a muscarinic antagonist and a histamine antagonist.
Option D: It is a muscarinic antagonist.
"	D
45266847	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC[NH+](CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O.[Cl-]
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a H1-receptor antagonist and a muscarinic antagonist.
Option B: It is a GABA antagonist and a serotonergic antagonist.
Option C: It is a muscarinic antagonist and a histamine antagonist.
Option D: It is a muscarinic antagonist.
"	D
60149	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F)CCN5CCNC5=O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a serotonin antagonist.
Option B: It is a serotonergic antagonist.
Option C: It is a serotonin receptor agonist.
Option D: It is a serotonin and tryptamine antagonist.
"	B
72168	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC1=NC(=C(N1CC2=CC3=C(C=C2)OC(=C3Br)C4=CC=CC=C4C5=NNN=N5)C(=O)O)Cl
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an angiotensin II receptor type 1 (AT1) antagonist.
Option B: It is an angiotensin receptor antagonist.
Option C: It is an endothelin receptor antagonist.
Option D: It is an angiotensin II receptor antagonist.
"	A
4919	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a muscarinic antagonist.
Option B: It is a GABA antagonist and a serotonergic antagonist.
Option C: It is a H1-receptor antagonist and a muscarinic antagonist.
Option D: It is a muscarinic antagonist and a histamine antagonist.
"	A
5002	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a serotonin receptor agonist.
Option B: It is a serotonergic antagonist.
Option C: It is a serotonin antagonist.
Option D: It is a serotonin and tryptamine antagonist.
"	B
132706	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC1=NN(C(=N1)CCCC)CC2=CN=C(C=C2)C3=CC=CC=C3C4=NNN=N4
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an angiotensin II receptor antagonist.
Option B: It is an angiotensin II receptor type 1 (AT1) antagonist.
Option C: It is an angiotensin receptor antagonist.
Option D: It is an endothelin receptor antagonist.
"	C
11790	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an orexin receptor antagonist.
Option B: It is an aryl hydrocarbon receptor antagonist.
Option C: It is an endothelin receptor antagonist.
Option D: It is an angiotensin receptor antagonist.
"	B
2381	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCN(CC1)CCC(C2CC3CC2C=C3)(C4=CC=CC=C4)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a muscarinic antagonist.
Option B: It is a muscarinic antagonist and a histamine antagonist.
Option C: It is a GABA antagonist and a serotonergic antagonist.
Option D: It is a H1-receptor antagonist and a muscarinic antagonist.
"	A
28693	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C[C@@H](C[C@H]2[C@H]1CC3=CN(C4=CC=CC2=C34)C)CNC(=O)OCC5=CC=CC=C5
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a 5-HT2 antagonist.
Option B: It is a 5-HT3 and 5-HT4 receptors antagonist.
Option C: It is a glutamate receptor antagonist.
Option D: It is an antagonist of 5-HT3 receptors.
"	A
4893	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an adrenergic antagonist.
Option B: It is a beta-adrenergic antagonist.
Option C: It is a selective alpha-1a adrenergic antagonist.
Option D: It is an alpha-adrenergic antagonist.
"	D
2690	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=COC(=C1)C2=NN3C(=N2)C4=C(C=CC(=C4)Cl)N=C3N
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor.
Option B: It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor.
Option C: It is a potent antagonist at adenosine A1 and adenosine A2A receptors.
Option D: It is a potent antagonist for both S1P1 and S1P3 receptors.
"	C
16082054	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC(=CC(=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C(CC(=O)C3=CC(=C(C=C3)O)OC)O)/C=C/CO
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a histamine antagonist.
Option B: It is a second-generation histamine H1 antagonist.
Option C: It is a H1 histamine receptor antagonist.
Option D: It is a histamine H1 antagonist.
"	A
16051	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCC(CC1)OC(=O)C(C2=CC=CC=C2)C3=CC=CC=C3
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a muscarinic antagonist and a histamine antagonist.
Option B: It is a H1-receptor antagonist and a muscarinic antagonist.
Option C: It is a GABA antagonist and a serotonergic antagonist.
Option D: It is a muscarinic antagonist.
"	D
3277600	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=NSC(=C1)NC(=O)NC2=CC3=C(C=C2)N(C=C3)C
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a potent and selective antagonist for the 5-hydroxytryptamine 1D (5-HT1D) receptor.
Option B: It is a potent and selective antagonist for the 5-hydroxytryptamine 2B (5-HT2B) receptor.
Option C: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
Option D: It is an H1 receptor agonist and partial H3 receptor antagonist used for the treatment of obese individuals and for other weight management indications.
"	B
4167	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCCC(C1)CC2C3=CC=CC=C3SC4=CC=CC=C24
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a GABA antagonist and a serotonergic antagonist.
Option B: It is a H1-receptor antagonist and a muscarinic antagonist.
Option C: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist.
Option D: It is a muscarinic antagonist and a histamine antagonist.
"	D
5281040	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C1=CC=CC=C1CC[C@H](C2=CC=CC(=C2)/C=C/C3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a Histamine-2 Receptor Antagonist.
Option B: It is a protease-activated receptor-1 antagonist.
Option C: It is a beta-1 adrenoceptor antagonist.
Option D: It is a Leukotriene Receptor Antagonist.
"	D
9887812	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC(=C1)C(=O)O)C2=CC(=CC=C2)NCCNC[C@@H](C3=CC(=CC=C3)Cl)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a long acting beta-adrenoceptor agonist.
Option B: It is a selective β3 adrenoceptor agonist.
Option C: It is a selective α1-receptor agonist.
Option D: It is a selective beta-2 adrenergic agonist.
"	B
5546	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C2=NC3=C(N=C(N=C3N=C2N)N)N
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a muscarinic antagonist.
Option B: It is a weak antagonist of folic acid.
Option C: It is used to counteract the toxic effects of folic acid antagonists.
Option D: It is a folic acid antagonist.
"	B
443872	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CCC(=O)C=C1C[C@H]([C@@H]3[C@]24[C@H](O4)C[C@]5([C@H]3CC[C@@]56CCC(=O)O6)C)C(=O)OC
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an aldosterone receptor antagonist and potassium-sparing diuretic.
Option B: It is an angiotensin receptor antagonist.
Option C: It is an angiotensin II receptor type 1 (AT1) antagonist.
Option D: It is an angiotensin II receptor antagonist.
"	A
10220503	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(=O)NC[C@@H]1C[C@H]1C2=C3CCOC3=CC=C2
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a selective serotonin agonist.
Option B: It is a melatonin receptor agonist.
Option C: It is a serotonin receptor agonist.
Option D: It is a serotonin antagonist.
"	B
56959087	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@]2([C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3CC=C)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an orally available cannabinoid agonist.
Option B: It is an Opioid Antagonist.
Option C: It is an alpha-adrenergic antagonist.
Option D: It is an adrenergic antagonist.
"	B
5401	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a selective alpha 1 antagonist.
Option B: It is an alpha-adrenergic antagonist.
Option C: It is a selective alpha-1a adrenergic antagonist.
Option D: It is an adrenergic antagonist.
"	A
5311507	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCN1CC/C=C\\2/C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a dopaminergic antagonist.
Option B: It is a dopamine antagonist.
Option C: It is an antagonist at D1 and D2 dopamine receptors.
Option D: It is a dopamine receptor D2 antagonist.
"	C
60947	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCC2CCNCC2)C(=O)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist.
Option B: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist.
Option C: It is a platelet glycoprotein-IIb/IIIa receptor antagonist.
Option D: It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor.
"	D
5833	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women.
Option B: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor.
Option C: It is an aldosterone receptor antagonist and potassium-sparing diuretic widely used in the therapy of edema, particularly in patients with cirrhosis.
Option D: It is an H1 receptor agonist and partial H3 receptor antagonist used for the treatment of obese individuals and for other weight management indications.
"	C
3373	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a benzodiazepine receptor agonist used for the treatment of insomnia.
Option B: It is a benzodiazepine receptor agonist and hypnotic used as a sleeping pill.
Option C: It is a benzodiazepine receptor agonist.
Option D: It is a Benzodiazepine Antagonist.
"	D
942	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCCC1C2=CN=CC=C2
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist.
Option B: It is a selective antagonist for the M3 muscarinic acetylcholine receptor.
Option C: It is an agonist at nicotinic cholinergic receptors.
Option D: It is a competitive, reversible antagonist of muscarinic receptors.
"	C
65015	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an antagonist of the cell-surface CXCR4 receptor.
Option B: It is a competitive, reversible antagonist of muscarinic receptors.
Option C: It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors.
Option D: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
"	A
2372	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=CC=C1)OCC(CNCCC2=CC(=C(C=C2)OC)OC)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an alpha1 adrenoceptor antagonist.
Option B: It is a H1-receptor antagonist.
Option C: It is a beta-1 adrenoceptor antagonist.
Option D: It is a glutamate receptor antagonist.
"	C
644073	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a histamine antagonist, a muscarinic antagonist, a serotonergic antagonist, a dopaminergic antagonist, and a serotonin uptake inhibitor.
Option B: It is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist.
Option C: It is a NMDA receptor antagonist, a H1-receptor antagonist, and a muscarinic antagonist.
Option D: It is a H1-receptor antagonist and a muscarinic antagonist.
"	B
10237	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a light-sensitive competitive antagonist of GABAA receptors.
Option B: It is a competitive, reversible antagonist of muscarinic receptors.
Option C: It is an antagonist of corticotropin-releasing factor 1 (CRF-1) receptors.
Option D: It is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.
"	A
969472	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCN(CC1)C(=O)O[C@H]2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a Benzodiazepine Antagonist.
Option B: It is a benzodiazepine receptor agonist used for the treatment of insomnia.
Option C: It is a benzodiazepine receptor agonist.
Option D: It is a benzodiazepine receptor agonist and hypnotic used as a sleeping pill.
"	C
5487	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an agonist at a2-adrenergic receptor sites.
Option B: It is a non-selective beta adrenergic receptor agonist.
Option C: It is a beta-3 adrenergic agonist.
Option D: It is a selective beta-2 adrenergic agonist.
"	A
24965990	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1CCN(CCN1C(=O)C2=C(C=CC(=C2)C)N3N=CC=N3)C4=NC5=C(O4)C=CC(=C5)Cl
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an angiotensin II receptor antagonist.
Option B: It is an angiotensin receptor antagonist.
Option C: It is an angiotensin II receptor type 1 (AT1) antagonist.
Option D: It is an orexin receptor antagonist.
"	D
5717	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a Leukotriene Receptor Antagonist.
Option B: It is a beta-1 adrenoceptor antagonist.
Option C: It is a Histamine-2 Receptor Antagonist.
Option D: It is a protease-activated receptor-1 antagonist.
"	A
5281037	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)/C=C(\\CC3=CC=CS3)/C(=O)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is an endothelin receptor antagonist.
Option B: It is an angiotensin receptor antagonist.
Option C: It is an angiotensin II receptor antagonist.
Option D: It is an angiotensin II receptor type 1 (AT1) antagonist.
"	C
148121	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a parenterally administered folate antagonist and antineoplastic agent.
Option B: It is a serotonergic antagonist and a dopaminergic antagonist.
Option C: It is a GABA antagonist and a serotonergic antagonist.
Option D: It is a folate antagonist and antineoplastic agent.
"	D
4919	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC(CC1)C(CCN2CCCC2)(C3=CC=CC=C3)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a muscarinic antagonist that crosses the blood-brain barrier.
Option B: It is a muscarinic antagonist.
Option C: It is a H1-receptor antagonist and a muscarinic antagonist.
Option D: It is a long-acting muscarinic antagonist (LAMA).
"	A
16158208	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O)C(=O)N[C@@H](CSSC[C@@H](C(=O)N3)N)C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N1)CC(=O)N)CC6=CC=C(C=C6)O)CCC(=O)O
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a benzodiazepine receptor agonist.
Option B: It is a benzodiazepine receptor agonist and hypnotic used as a sleeping pill.
Option C: It is a benzodiazepine receptor agonist used for the treatment of insomnia.
Option D: It is a peptide agonist of guanylate cyclase 2C.
"	D
3157	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a non-selective beta adrenergic receptor agonist.
Option B: It is a nonselective alpha-adrenergic antagonist (alpha-blocker).
Option C: It is a non-opioid centrally acting alpha2-adrenergic receptor agonist.
Option D: It is a nonselective alpha-1 adrenergic antagonist (alpha-blocker).
"	D
4893	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a non-opioid centrally acting alpha2-adrenergic receptor agonist.
Option B: It is a nonselective alpha-adrenergic antagonist (alpha-blocker).
Option C: It is a non-selective beta adrenergic receptor agonist.
Option D: It is a nonselective alpha-1 adrenergic antagonist (alpha-blocker).
"	B
5265	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCC(=O)C4=CC=C(C=C4)F
Question about this molecule: Which kind of antagonist is this molecule?
Option A: It is a dopaminergic antagonist.
Option B: It is a dopamine receptor D2 antagonist.
Option C: It is a histamine antagonist.
Option D: It is a dopamine antagonist.
"	D
150610	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)NC4=CC=CC(=C4)C(=O)O)C(=O)O)[C@@H](C)O
Question about this molecule: How can the molecule be used as a/an antibacterial drug
Option A: It is an antibacterial drug used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections and against visceral leishmaniasis.
Option B: The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract.
Option C: It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Option D: It is used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis.
"	B
9553856	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1COCCN1CC2CN(C(=O)O2)/N=C/C3=CC=C(O3)[N+](=O)[O-]
Question about this molecule: How can the molecule be used as a/an antibacterial drug
Option A: It is used as an antibacterial drug for the treatment of skin infections.
Option B: It is used to treat bronchitis as well as ear, skin and other bacterial infections.
Option C: It is used topically for treatment of ear disorders.
Option D: It is used for the treatment of bacterial leaf blight in paddy rice.
"	C
5335	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)N2C(=CC=N2)NS(=O)(=O)C3=CC=C(C=C3)N
Question about this molecule: How can the molecule be used as a/an antibacterial drug
Option A: It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.
Option B: A lipophilic antibacterial drug mainly used in spray dosage forms for the local treatment of infection and inflammation of the throat.
Option C: It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections.
Option D: It is used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis.
"	A
447043	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
Question about this molecule: How can the molecule be used as a/an antibacterial drug
Option A: It is an antibacterial agent used as an ingredient in toothpastes.
Option B: It is used as an antibacterial drug for the treatment of skin infections.
Option C: It is a macrolide antibiotic useful for the treatment of bacterial infections.
Option D: It is an antibacterial agent used for veterinary use against bacterial infections.
"	C
44187	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
Question about this molecule: Which kind of antibacterial drug is this molecule?
Option A: It is a Cephalosporin Antibacterial.
Option B: It is a Rifamycin Antibacterial.
Option C: It is a Penem Antibacterial.
Option D: It is a Nitrofuran Antibacterial.
"	A
441401	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
Question about this molecule: Which kind of antibacterial drug is this molecule?
Option A: It is a Nitrofuran Antibacterial.
Option B: It is a synthetic fluoroquinolone antibacterial agent.
Option C: It is an Oxazolidinone Antibacterial.
Option D: It is a Fluoroquinolone Antibacterial.
"	C
38103	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(N2[C@@H]([C@@H](C2=O)NC(=O)[C@@H](C3=CCC=CC3)N)SC1)C(=O)O
Question about this molecule: Which kind of antibacterial drug is this molecule?
Option A: It is a Cephalosporin Antibacterial.
Option B: It is a Penem Antibacterial.
Option C: It is a Nitrofuran Antibacterial.
Option D: It is a Rifamycin Antibacterial.
"	A
441130	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)N(C)C)C(=O)O)[C@@H](C)O
Question about this molecule: Which kind of antibacterial drug is this molecule?
Option A: It is a Rifamycin Antibacterial.
Option B: It is a Penem Antibacterial.
Option C: It is a Cephalosporin Antibacterial.
Option D: It is a Nitrofuran Antibacterial.
"	B
150610	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)NC4=CC=CC(=C4)C(=O)O)C(=O)O)[C@@H](C)O
Question about this molecule: Which kind of antibacterial drug is this molecule?
Option A: It is a Cephalosporin Antibacterial.
Option B: It is a Nitrofuran Antibacterial.
Option C: It is a Penem Antibacterial.
Option D: It is a Rifamycin Antibacterial.
"	C
12894	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(OC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C
Question about this molecule: Which kind of antibacterial drug is this molecule?
Option A: It is an antibacterial in the sulfonamide class.
Option B: It is a Rifamycin Antibacterial.
Option C: It is one of the sulfa drugs.
Option D: It is a Sulfonamide Antibacterial.
"	A
5479529	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CO/N=C(/C1=CC=CO1)\\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)COC(=O)N)C(=O)O
Question about this molecule: Which kind of antibacterial drug is this molecule?
Option A: It is a Nitrofuran Antibacterial.
Option B: It is a Penem Antibacterial.
Option C: It is a Cephalosporin Antibacterial.
Option D: It is a Rifamycin Antibacterial.
"	C
70678896	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H]1/C=C(/[C@H](C/C=C/C=C(/C(=O)OC(C/C=C(/C=C(/[C@@H]1O[C@H]2[C@H]([C@H]([C@@H](C(O2)(C)C)OC(=O)C(C)C)O)O)\\C)\\C)[C@@H](C)O)\\CO[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)\\C
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections.
Option B: It is a narrow spectrum antibiotic used for treatment of Clostridium difficile-related infections.
Option C: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.
Option D: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections.
"	B
25243252	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C(=O)[C@@]23CC4=C(N2C(=O)[C@@]1(SS3)CO)C=C(C=C4)[N+](=O)[O-]
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is used for urinary tract infections and in veterinary medicine.
Option B: It is used to treat potentially life-threatening fungal infections.
Option C: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections.
Option D: It exhibits cytotoxic activity against human cancer cell lines.
"	D
6537204	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@H]([C@H]2[C@@](O2)(/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)CC=O)C)C)C
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: The molecule is a macrolide that is isolated from several Streptomyces species and displays antibiotic properties.
Option B: It is an antibiotic produced by Streptomyces achromogenes.
Option C: It is an antibiotic with antibacterial activity.
Option D: It is a macrolide antibiotic with activity against specific bacteria.
"	D
64939	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=NSN=C1NS(=O)(=O)C2=CC=C(C=C2)N
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is an alkaloid antibiotic.
Option B: It is a nitrofuran antibiotic.
Option C: It is a sulfonamide antibiotic.
Option D: It is a polyether antibiotic.
"	C
54729367	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCO.C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)[NH+](C)C)O.C[C@@H]1[C@H]2[C@@H]([C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)[NH+](C)C)O.O.[Cl-].[Cl-]
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia.
Option B: It is used for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.
Option C: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.
Option D: It is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.
"	D
12894	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(OC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is an antimicrobial agent.
Option B: It is an antibacterial drug and an antimicrobial agent.
Option C: It is an antibacterial agent and an antimicrobial agent.
Option D: It is an antimicrobial agent and an antibacterial agent.
"	A
135413542	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CNC[C@@H]1N2CC/C(=C\\C3=C(N4[C@@H]([C@@H](C4=O)NC(=O)/C(=N\\O)/C5=NSC(=N5)N)SC3)C(=O)O)/C2=O
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is an antibacterial agent and an antimicrobial agent.
Option B: It is an antibacterial drug and an antimicrobial agent.
Option C: It is an antimicrobial agent.
Option D: It is an antimicrobial agent and an antibacterial agent.
"	C
73423	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1C=C[C@@H](O1)[C@@H](C(=O)O)N
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is an antibacterial agent and an antimicrobial agent.
Option B: It is an antimicrobial agent and an antiinfective agent.
Option C: It is an antimicrobial agent and an antibacterial agent.
Option D: It is an antibacterial drug and an antimicrobial agent.
"	C
168966	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=C2C(=C1)OC3(C2=O)C(=CC(=O)C=C3OC)C(=O)OC)O
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is an antimicrobial agent and an antibacterial agent.
Option B: It is an antibacterial agent and an antimicrobial agent.
Option C: It is an antibacterial drug and an antimicrobial agent.
Option D: It is an antimicrobial agent.
"	D
166548	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC=C(C=C7)O)O)O)[C@@H](C)O)C)O)O)O
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections.
Option B: It is a narrow spectrum antibiotic used for treatment of Clostridium difficile-related infections.
Option C: It is used for the treatment of invasive candidiasis.
Option D: It is useful for the treatment of bacterial infections.
"	C
477468	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCOC1=CC=C(C=C1)C2=CC(=NO2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC(=C(C=C7)O)OS(=O)(=O)O)O)O)[C@@H](CC(=O)N)O)C)O)O)O
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is used for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.
Option B: It is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis.
Option C: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia.
Option D: The molecule is a cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
"	D
135398736	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1[C@@H](C(=O)N1S(=O)(=O)[O-])NC(=O)/C(=N\\OC(C)(C)C(=O)O)/C2=CSC(=[NH+]2)N
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: Used to treat a wide range of infections caused by both gram-positive and gram-negative bacteria.
Option B: It has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms.
Option C: It is used primarily to treat infections caused by Gram-negative bacteria.
Option D: It is a broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria.
"	C
447451	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]2([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H](C(=O)[C@H](C(=O)O1)C)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC/C=C/C4=CC5=CC=CC=C5N=C4)C)C)NC(=O)O2)C
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: Used in combination with ceftazidime pentahydrate for the treatment of complicated urinary tract infections including pyelonephritis.
Option B: It is used to treat acne, urinary tract infections, gum disease, and other bacterial infections such as gonorrhoea and chlamydia.
Option C: Used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections.
Option D: It displays in vitro activity against both gram-positive and gram-negative bacteria and is currently under investigation for the treatment of community-acquired pneumonia.
"	D
447043	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
Question about this molecule: How can the molecule be used as a/an antibiotic
Option A: It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections.
Option B: It is a narrow spectrum antibiotic used for treatment of Clostridium difficile-related infections.
Option C: It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections.
Option D: It is useful for the treatment of bacterial infections.
"	D
8982	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=C(C2=CC=CC=C2C=C1)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is an oral, second generation penicillin antibiotic used to treat bacterial infections caused by penicillinase-resistant staphylococci.
Option B: It is a parenteral, second generation penicillinase-resistant penicillin antibiotic used largely to treat moderate to severe staphylococcal infections.
Option C: It is a second generation penicillin antibiotic used for penicillinase-resistant staphylococcal infections.
Option D: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms.
"	B
44187	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA).
Option B: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa.
Option C: It is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
Option D: It is a third-generation antibiotic agent used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia.
"	D
441401	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa.
Option B: It is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
Option C: It is a third-generation antibiotic agent used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia.
Option D: It is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA).
"	D
135413542	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CNC[C@@H]1N2CC/C(=C\\C3=C(N4[C@@H]([C@@H](C4=O)NC(=O)/C(=N\\O)/C5=NSC(=N5)N)SC3)C(=O)O)/C2=O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents.
Option B: It is a macrocyclic antibiotic with major activity against mycobacteria, commonly used in combination with other agents as therapy of tuberculosis.
Option C: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa.
Option D: It is a cephalosporin antibiotic with activity against methicillin-resistant Staphylococcus aureus.
"	D
447043	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a semisynthetic macrolide antibiotic commonly used for a wide variety of mild-to-moderate bacterial infections.
Option B: It is a carbapenem antibiotic with broad spectrum of activity administered intravenously and used for severe bacterial infections due to sensitive agents.
Option C: It is a broad spectrum antibiotic that was shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available.
Option D: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms.
"	A
11567473	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)C#N)N4C[C@H]5[C@H](C4)OCCN5)F)C(=O)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a third-generation antibiotic agent used in the treatment of various bacterial infections caused by susceptible organisms in the body, including respiratory tract infections, peritonitis, skin infections, endometritis, and bacterial septicemia.
Option B: It is a third-generation cephalosporin antibiotic with broad-spectrum antibacterial activity, including against some treatment-resistant bacteria such as Pseudomonas aeruginosa.
Option C: It is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA).
Option D: It is a fluoroquinolone antibiotic indicated in the treatment of acute otitis externa (swimmer's ear) caused by the bacteria Pseudomonas aeruginosa and Staphylococcus aureus.
"	D
441130	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)N(C)C)C(=O)O)[C@@H](C)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a broad spectrum aminoglycoside antibiotic typically used for treatment of active tuberculosis, always in combination with other antituberculosis agents.
Option B: It is a carbapenem antibiotic with broad spectrum of activity administered intravenously and used for severe bacterial infections due to sensitive agents.
Option C: It is a parenterally administered, broad spectrum aminoglycoside antibiotic used in the treatment of moderate to severe bacterial infections due to sensitive organisms.
Option D: It is a broad spectrum antibiotic that was shown to cause serious and fatal aplastic anemia and is now used rarely and reserved for severe, life-threatening infections for which other antibiotics are not available.
"	B
54686187	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)NCN5CCN(CC5)CCO)N(C)C)O.CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)COC3=CC=CC=C3)C(=O)O)C
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a glycycline antibiotic used for serious infections.
Option B: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne.
Option C: It is a tetracycline used to treat bacterial infections.
Option D: It is a tetracycline class antibiotic used in humans.
"	D
6473883	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]([C@H]2[C@H]([C@H]([C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O[C@H]4[C@@H]([C@H](C[C@H](O4)C)N(C)C)O)(C)O)C)N[C@H](O2)COCCOC)C)(C)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a macrocyclic antibiotic.
Option B: It is a narrow spectrum antibiotic.
Option C: It is a macrolide glycopeptide antibiotic.
Option D: It is a glycopeptide antibiotic.
"	C
150610	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)NC4=CC=CC(=C4)C(=O)O)C(=O)O)[C@@H](C)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a narrow spectrum antibiotic.
Option B: It is a broad spectrum aminoglycoside antibiotic.
Option C: It is a broad-spectrum cephalosporin antibiotic.
Option D: It is a broad spectrum carbapenem antibiotic.
"	D
287180	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1C=C(C(=O)C2=C1C=C(C=C2)C3=CC=NC=C3)C(=O)O
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a quinolone derivative antibiotic used for various bacterial infections.
Option B: It is a tetracycline used to treat bacterial infections.
Option C: It is a glycycline antibiotic used for serious infections.
Option D: It is a tetracycline antibiotic used for several bacterial infections as well as treatment of acne.
"	A
135403821	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1/C=C/C=C(\\C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C=N/N5CCN(CC5)C6CCCC6)/C
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a broad-spectrum cephalosporin antibiotic.
Option B: It is a rifamycin antibiotic.
Option C: It is a broad spectrum carbapenem antibiotic.
Option D: It is a narrow spectrum antibiotic.
"	B
656958	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN(CC)CCSCC(=O)O[C@@H]1C[C@@]([C@H]([C@@H]([C@@]23CC[C@H]([C@@]1([C@@H]2C(=O)CC3)C)C)C)O)(C)C=C
Question about this molecule: Which kind of antibiotic is this molecule?
Option A: It is a second generation cephalosporin antibiotic.
Option B: It is a first-generation cephalosporin antibiotic that is available in injectable formulations.
Option C: It is a pleuromutilin antibiotic drug.
Option D: It is a third-generation cephalosporin antibiotic.
"	C
4909	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC1(C(=O)NCNC1=O)C2=CC=CC=C2
Question about this molecule: Which kind of anticonvulsant is this molecule?
Option A: It is an aromatic anticonvulsant used to treat complex, partial and generalized seizures.
Option B: It is used as an anticonvulsant in the therapy of partial onset seizures.
Option C: It is a unique anticonvulsant used largely as an adjunctive agent in the treatment of partial seizures.
Option D: It is a unique anticonvulsant used as adjunctive therapy in management of epilepsy and for neuropathic pain syndromes.
"	A
4199	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3
Question about this molecule: How can the molecule be used as a/an antidepressant
Option A: It antagonizes behavioral despair.
Option B: It is widely used in the therapy of depression.
Option C: It is widely used in therapy of depression and smoking cessation.
Option D: It is used for the treatment of moderate to severe depression.
"	A
3373	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)F)C
Question about this molecule: Which kind of antidote is this molecule?
Option A: It is an antidote to benzodiazepine poisoning.
Option B: It is an antidote to opioid poisoning.
Option C: It is an experimental antidote for cyanide poisoning.
Option D: It is an antidote to cyanide poisoning.
"	A
2342	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN(CC)C(=O)C1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C)OC)OC
Question about this molecule: Which kind of antiemetic is this molecule?
Option A: It is effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Option B: It is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties.
Option C: It is used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats.
Option D: It is used to treat and prevent postoperative nausea and vomiting in adults, either as monotherapy or in combination with another antiemetic agent of a different drug class.
"	B
3559	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
Question about this molecule: Which kind of antiemetic is this molecule?
Option A: It is a potent antiemetic and is used in the treatment of intractable hiccups.
Option B: It is used as an antiemetic and in the treatment of intractable hiccup.
Option C: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Option D: It is used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats.
"	A
25137957	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCN4CCN(CC4)CCO
Question about this molecule: Which kind of antiemetic is this molecule?
Option A: It is used as an antipsychotic agent and as an antiemetic.
Option B: These drugs have antipsychotic and, often, antiemetic properties.
Option C: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Option D: It is used as an antipsychotic and an antiemetic.
"	B
5577	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCOC1=CC=C(C=C1)CNC(=O)C2=CC(=C(C(=C2)OC)OC)OC
Question about this molecule: Which kind of antiemetic is this molecule?
Option A: It has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Option B: It is used in the therapy of nausea and vomiting associated with medications and gastrointestinal, viral and other illnesses.
Option C: It is used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats.
Option D: It is effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
"	B
3055	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O
Question about this molecule: Which kind of antiemetic is this molecule?
Option A: It is used to prevent postoperative or cancer chemotherapy related nausea and vomiting.
Option B: It is widely used in nausea and vomiting.
Option C: It is used to prevent cancer chemotherapy related nausea and vomiting.
Option D: It is used in the treatment of vomiting and vertigo.
"	D
26033	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC(=O)C1=CN2C(=CC(=N2)OP(=S)(OCC)OCC)N=C1C
Question about this molecule: Which kind of antifungal agrochemical is this molecule?
Option A: It is a novel systemic fungicide.
Option B: It is a novel fungicide.
Option C: It is a profungicide.
Option D: It is an obsolete fungicide.
"	C
73675	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[Si](CN1C=NC=N1)(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F
Question about this molecule: Which kind of antifungal agrochemical is this molecule?
Option A: It is a foliar fungicide.
Option B: It is a broad spectrum agricultural fungicide.
Option C: It is a broad spectrum fungicide.
Option D: It is a broad-spectrum fungicide.
"	D
9796266	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C(=C1)C#N)NC(=O)C2=C(C(=NS2)Cl)Cl
Question about this molecule: Which kind of antifungal agrochemical is this molecule?
Option A: It is a fungicide used for various horticultural crops.
Option B: It is an anti-peronosporic fungicide.
Option C: It is a fungicide used for the control of rice blast.
Option D: It is a foliar fungicide.
"	C
18771	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C2C(=C1)C(=O)C3=C(C2=O)SC(=C(S3)C#N)C#N
Question about this molecule: Which kind of antifungal agrochemical is this molecule?
Option A: It is a broad-spectrum fungicide.
Option B: It is a broad spectrum fungicide.
Option C: It is a broad spectrum agricultural fungicide.
Option D: It is a foliar fungicide.
"	B
56945144	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)OC(=O)NC1=CC=CC(=N1)CO/N=C(/C2=CC=CC=C2)\\C3=NN=NN3C
Question about this molecule: Which kind of antifungal agrochemical is this molecule?
Option A: It is a foliar fungicide.
Option B: It is a novel fungicide.
Option C: It is an obsolete fungicide.
Option D: It is a novel systemic fungicide.
"	B
52937280	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=C(C(=C1C2=C(C(=C(C=C2C)O)C(=O)C3=C(C=CC(=C3C)O)O)O)O)C(=O)C4=C(C=CC(=C4C)O)O)O
Question about this molecule: How can the molecule be used as a/an antifungal drug
Option A: It has a role as a metabolite, an antifungal agent, and an antibacterial agent. It can be used as an antifungal drug.
Option B: It has a role as an antibacterial agent, an antifungal agent, and a Penicillium metabolite. It can be used as an antifungal drug.
Option C: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug.
Option D: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug.
"	C
484757	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1[C@H]2[C@H]3[C@H]([C@@H](C4=C3C=C(C=C4O)O)C5=CC=C(C=C5)O)C6=C2C(=CC(=C6)O)O)O
Question about this molecule: How can the molecule be used as a/an antifungal drug
Option A: It has a role as an antioxidant, an antifungal agent, and a plant metabolite. It can be used as an antifungal drug.
Option B: It has a role as an antifungal agent and a marine metabolite. It can be used as an antifungal drug.
Option C: It has a role as an antifungal agent and a fungal metabolite. It can be used as an antifungal drug.
Option D: It has a role as a metabolite, an antifungal agent, and an antioxidant. It can be used as an antifungal drug.
"	A
5510	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2
Question about this molecule: How can the molecule be used as a/an antifungal drug
Option A: It is a synthetic anti-fungal agent used to treat jock itch, athlete's foot, and ringworm. It can be used as an antifungal drug.
Option B: It has a role as an immunosuppressive agent, an antifungal agent, and a bacterial metabolite. It can be used as an antifungal drug.
Option C: It has a role as an antibacterial agent, an antifungal agent, and a fungal metabolite. It can be used as an antifungal drug.
Option D: It has a role as an antioxidant, an antifungal agent, and a plant metabolite. It can be used as an antifungal drug.
"	A
1371749	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC(CC1)C(=O)NC2=NC=C(S2)CC3=CC=CC4=CC=CC=C43
Question about this molecule: How can the molecule be used as a/an antifungal drug
Option A: It has a role as an antifungal agent and a marine metabolite. It can be used as an antifungal drug.
Option B: It has a role as an antifungal agent and a fungal metabolite. It can be used as an antifungal drug.
Option C: It has been shown to exhibit antifungal activity. It can be used as an antifungal drug.
Option D: It has been used as a topical antifungal agent. It can be used as an antifungal drug.
"	C
489181	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3
Question about this molecule: How can the molecule be used as a/an antifungal drug
Option A: It has a role as an antifungal agent and a fungal metabolite. It can be used as an antifungal drug.
Option B: It is an antifungal drug used for the topical treatment of onychomycosis.
Option C: It has a role as an antifungal agent and a marine metabolite. It can be used as an antifungal drug.
Option D: It has a role as an Aspergillus metabolite and an antifungal agent. It can be used as an antifungal drug.
"	B
71616	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H](C1=NC=NC=C1F)[C@](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O
Question about this molecule: How can the molecule be used as a/an antifungal drug
Option A: It has been shown to exhibit antifungal activity. It can be used as an antifungal drug.
Option B: It is a triazole antifungal drug.
Option C: It is a triazole-based antifungal agent.
Option D: It is a potent broad spectrum antifungal agent.
"	C
135409642	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)OCC6=C(OC(=O)O6)C
Question about this molecule: How can the molecule be used as a/an antihypertensive agent
Option A: It is a prodrug for azilsartan, used for treatment of hypertension.
Option B: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist.
Option C: It is used for the treatment of hypertension as a nonpeptide antagonist of angiotensin II, type 1 (AT1) receptors.
Option D: It is used for treatment of hypertension and chronic heart failure as an inhibitor of angiotensin converting enzyme (ACE).
"	A
3157	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
Question about this molecule: How can the molecule be used as a/an antihypertensive agent
Option A: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist.
Option B: It is used in the treatment of high blood pressure as an antihypertensive agent.
Option C: It is used for the treatment of high blood pressure as a selective alpha1-adrenoceptor antagonist.
Option D: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent.
"	B
441975	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1[C@H]2CN3CCC4=C([C@@H]3C[C@@H]2C(=CO1)C(=O)OC)NC5=CC=CC=C45
Question about this molecule: How can the molecule be used as a/an antihypertensive agent
Option A: It is used in the treatment of high blood pressure as an antihypertensive agent.
Option B: It is used for the treatment of high blood pressure as a selective alpha1-adrenoceptor antagonist.
Option C: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent.
Option D: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist.
"	B
132706	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC1=NN(C(=N1)CCCC)CC2=CN=C(C=C2)C3=CC=CC=C3C4=NNN=N4
Question about this molecule: How can the molecule be used as a/an antihypertensive agent
Option A: It is used for the treatment of hypertension as a nonpeptide antagonist of angiotensin II, type 1 (AT1) receptors.
Option B: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist.
Option C: It is used for treatment of hypertension and chronic heart failure as an inhibitor of angiotensin converting enzyme (ACE).
Option D: It is used for treatment of neurogenic orthostatic hypotension as a vasoconstrictor agent and an antihypertensive agent.
"	A
23699544	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)[N-]5)C(=O)OCC6=C(OC(=O)O6)C.[K+]
Question about this molecule: How can the molecule be used as a/an antihypertensive agent
Option A: It is a prodrug for azilsartan, used for treatment of hypertension.
Option B: It is used mainly for the treatment of hypertension as an angiotensin II receptor antagonist.
Option C: It is used for treatment of hypertension and chronic heart failure as an inhibitor of angiotensin converting enzyme (ACE).
Option D: It is used for the treatment of hypertension as a nonpeptide antagonist of angiotensin II, type 1 (AT1) receptors.
"	A
447043	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
Question about this molecule: Which kind of antimicrobial is this molecule?
Option A: It is a Quinolone Antimicrobial.
Option B: It is a This molecule-class Antimicrobial.
Option C: It is a Macrolide Antimicrobial.
Option D: It is a Sulfonamide Antimicrobial.
"	C
11567473	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)C#N)N4C[C@H]5[C@H](C4)OCCN5)F)C(=O)O
Question about this molecule: Which kind of antimicrobial is this molecule?
Option A: It is a Sulfonamide Antimicrobial.
Option B: It is a This molecule-class Antimicrobial.
Option C: It is a Macrolide Antimicrobial.
Option D: It is a Quinolone Antimicrobial.
"	D
121875	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCN2[C@H](C1)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C2=O)CC3=CC=CC=C3)CC4=CC=CC=C4)CCCCCC(=O)[C@@H]5CO5
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is an oral selective BCL-2 inhibitor and antineoplastic agent.
Option B: It is a histone deacetylase (HDAC) inhibitor.
Option C: It is an EC 3.5.1.98 (histone deacetylase) inhibitor.
Option D: It is an oral histone deacetylase inhibitor and antineoplastic agent.
"	C
11625818	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H](C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is an antineoplastic agent used for the treatment of refractory indolent non-Hodgkin's lymphoma and relapsed chronic lymphocytic leukemia.
Option B: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
Option C: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.
Option D: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer.
"	A
24864821	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC2=NC=CC(=C2C=C1)OCC3=NN=C4N3N=C(C=C4)C5=CC=CC=C5
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is an antimetabolite antineoplastic agent.
Option B: It is an antimetabolite.
Option C: It exhibits some anticancer properties.
Option D: It exhibits antitumour activity, particularly in prostate cancer.
"	D
77050682	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC(=C3N4CCC5(CCNC5=O)CC4)Cl
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is a protein synthesis inhibitor.
Option B: It is a Wnt signalling inhibitor.
Option C: It is a proteasome inhibitor.
Option D: It is a Hsp90 inhibitor.
"	B
148121	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is an antimetabolite and a radiosensitizing agent.
Option B: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor.
Option C: It is an antimetabolite and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor.
Option D: It is an antimetabolite antineoplastic agent.
"	C
49867926	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is a proteasome inhibitor.
Option B: It is a Hsp90 inhibitor.
Option C: It is a protein synthesis inhibitor.
Option D: It is a mTOR inhibitor.
"	D
91865076	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2C1)CCCCN)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)[C@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C6=CC=C(C=C6)F)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N)CCCNC(=O)N)CCCNC(=N)N)CC7=CC=C(C=C7)O
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is a fibroblast growth factor receptor antagonist and a vascular endothelial growth factor receptor antagonist.
Option B: It is a SMO receptor antagonist and a Hedgehog signaling pathway inhibitor.
Option C: It is a NF-kappaB inhibitor and a p53 activator.
Option D: It is a C-X-C chemokine receptor type 4 antagonist.
"	D
11556711	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is an inhibitor of microtubule function and is used as an antineoplastic agent.
Option B: It is an irreversible proteasome inhibitor and antineoplastic agent.
Option C: It is an oral selective BCL-2 inhibitor and antineoplastic agent.
Option D: It is an antineoplastic agent that acts by inhibitor of cellular mitosis.
"	B
2179	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Option B: It is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis.
Option C: It is an antineoplastic agent that acts by inhibitor of cellular mitosis.
Option D: It is frequently used in combination with other antineoplastic agents in chemotherapy protocols.
"	D
148121	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is a parenterally administered folate antagonist and antineoplastic agent used in the treatment of peripheral T cell lymphomas.
Option B: It is a purine analogue and antineoplastic agent used in the therapy of acute lymphoblastic leukemia (ALL) in children.
Option C: It is a purine analogue and antineoplastic agent used in the therapy of T cell lymphoblastic leukemia or lymphoma.
Option D: It is a purine analogue and antineoplastic agent used primarily in the therapy of hairy cell leukemia.
"	A
9829523	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer.
Option B: It is an antineoplastic agent used for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.
Option C: It is an orally available small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3) used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations.
Option D: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.
"	C
89683805	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It is an antineoplastic agent used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.
Option B: It is an antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Option C: It is an orally available small molecule inhibitor of isocitrate dehydrogenase and antineoplastic agent used in the therapy of selected cases of acute myeloid leukemia (AML).
Option D: It is a cytosine analogue and intravenously administered antineoplastic agent used in the therapy of several forms of advanced, pancreatic, lung, breast, ovarian, and bladder cancer.
"	C
5288209	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)NC2=CC=C(C=C2)O)/C)/C
Question about this molecule: Which kind of antineoplastic agent is this molecule?
Option A: It has been used as an antineoplastic agent.
Option B: It is also effective as an antineoplastic agent.
Option C: It is a bacterial enzyme that is used as an antineoplastic agent.
Option D: It is an antimetabolite antineoplastic agent.
"	B
11556711	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Question about this molecule: What is the right antineoplastic agent information about this molecule?
Option A: It is used in the treatment of refractory multiple myeloma.
Option B: It is used as an antineoplastic agent in the therapy of T cell lymphoblastic leukemia or lymphoma.
Option C: It is used as an antineoplastic agent in treatment of refractory multiple myeloma and certain lymphomas.
Option D: It is used as an antineoplastic agent in the treatment of peripheral T cell lymphomas.
"	A
2179	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
Question about this molecule: What is the right antineoplastic agent information about this molecule?
Option A: It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Option B: It is used as an antineoplastic agent largely in the therapy of acute leukemia.
Option C: It is frequently used in combination with other antineoplastic agents in chemotherapy protocols.
Option D: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML).
"	C
148121	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Question about this molecule: What is the right antineoplastic agent information about this molecule?
Option A: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children.
Option B: It is used as an antineoplastic agent in the treatment of peripheral T cell lymphomas.
Option C: It is used as an antineoplastic agent in the therapy of T cell lymphoblastic leukemia or lymphoma.
Option D: It is used as an antineoplastic agent in treatment of refractory multiple myeloma and certain lymphomas.
"	B
9829523	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Question about this molecule: What is the right antineoplastic agent information about this molecule?
Option A: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children.
Option B: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations.
Option C: It is used as an antineoplastic agent largely in the therapy of acute leukemia.
Option D: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML).
"	B
89683805	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O
Question about this molecule: What is the right antineoplastic agent information about this molecule?
Option A: It is used as an antineoplastic agent in the treatment of acute myeloid leukemia with FLT3 mutations.
Option B: It is used as an antineoplastic agent largely in the therapy of acute leukemia.
Option C: It is used as an antineoplastic agent in the therapy of selected cases of acute myeloid leukemia (AML).
Option D: It is used as an antineoplastic agent in the therapy of acute lymphoblastic leukemia (ALL) in children.
"	C
5288209	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)NC2=CC=C(C=C2)O)/C)/C
Question about this molecule: What is the right antineoplastic agent information about this molecule?
Option A: It is an immunomodulatory antineoplastic agent.
Option B: It is effective as an antineoplastic agent.
Option C: It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Option D: It has been used as an antineoplastic agent.
"	B
3293	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C
Question about this molecule: How can the molecule be used as a/an antioxidant
Option A: It is used as an antioxidant in food, e.g. oils and fats.
Option B: It is used as an antioxidant for mucolytic therapy and the treatment of [acetaminophen] overdose.
Option C: It acts as an antioxidant against the auto-oxidation of animal and vegetable fats.
Option D: It is used as an antioxidant in animal feeds and for the preservation of color in the production of chili powder, paprika, and ground chili.
"	D
36207	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)C.C1=CC=C(C=C1)S(=O)(=O)O
Question about this molecule: Which kind of antipsychotic is this molecule?
Option A: It is a potent neuroleptic with antipsychotic properties.
Option B: It is a Typical Antipsychotic.
Option C: It is a second generation antipsychotic.
Option D: It is a first generation antipsychotic.
"	D
5002	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42
Question about this molecule: Which kind of antipsychotic is this molecule?
Option A: It is a second generation antipsychotic.
Option B: It is a potent neuroleptic with antipsychotic properties.
Option C: It is a Typical Antipsychotic.
Option D: It is a first generation antipsychotic.
"	A
25137957	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCN4CCN(CC4)CCO
Question about this molecule: Which kind of antipsychotic is this molecule?
Option A: It is a phenothiazine used as an antipsychotic agent and as an antiemetic.
Option B: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder.
Option C: It is a phenothiazine antipsychotic drug.
Option D: It is a phenothiazine antipsychotic used principally in the treatment of nausea, vomiting, and vertigo.
"	C
3559	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
Question about this molecule: Which kind of antipsychotic is this molecule?
Option A: It is a Typical Antipsychotic.
Option B: It is a first generation antipsychotic.
Option C: It is a potent neuroleptic with antipsychotic properties.
Option D: It is a second generation antipsychotic.
"	A
5736	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCOC1=CC2=CC=CC=C2SC3=C1C=C(C=C3)Cl
Question about this molecule: Which kind of antipsychotic is this molecule?
Option A: It is an atypical antipsychotic used in the treatment of schizophrenia and manic or mixed episodes of bipolar disorder.
Option B: It is an atypical antipsychotic used in the treatment of adults with schizophrenia and bipolar disorder.
Option C: It has been used as an antipsychotic in Japan, India, and some places in Europe like UK and Germany since the 1980s.
Option D: It is an atypical antipsychotic used in the treatment of schizophrenia and bipolar illness.
"	C
3010818	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5
Question about this molecule: Which kind of antiviral drug is this molecule?
Option A: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C.
Option B: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B.
Option C: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C.
Option D: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C.
"	D
54767916	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)NC2=CC=C(C=C2)[C@@H]3CC[C@H](N3C4=CC=C(C=C4)C(C)(C)C)C5=CC=C(C=C5)NC(=O)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
Question about this molecule: Which kind of antiviral drug is this molecule?
Option A: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C.
Option B: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C.
Option C: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C.
Option D: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B.
"	A
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: Which kind of antiviral drug is this molecule?
Option A: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C.
Option B: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C.
Option C: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B.
Option D: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C.
"	A
44603531	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)[C@H]1C(=O)N2C[C@@H](C[C@H]2C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C4CC4)OC5=NC6=C(C=CC(=C6)OC)N=C5CCCCC[C@@H]7C[C@H]7OC(=O)N1
Question about this molecule: Which kind of antiviral drug is this molecule?
Option A: It is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C.
Option B: It is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C.
Option C: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B.
Option D: It is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C.
"	B
159269	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN(C(=O)NC1=O)[C@@H]2C[C@H]([C@@H](O2)CO)O
Question about this molecule: Which kind of antiviral drug is this molecule?
Option A: It is a nucleoside analogue and antiviral inhibitor of hepatitis B virus (HBV) replication which is used alone and in combination with other agents in the therapy of the hepatitis B.
Option B: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B.
Option C: It is used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.
Option D: It is used for therapy of severe novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) infection.
"	A
121304016	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4
Question about this molecule: Which kind of antiviral drug is this molecule?
Option A: It is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A and B.
Option B: It is used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis.
Option C: It is a nucleoside analogue and antiviral inhibitor of hepatitis B virus (HBV) replication which is used alone and in combination with other agents in the therapy of the hepatitis B.
Option D: It is used for therapy of severe novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) infection.
"	D
11979606	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(=CC=C1)C)OCC(=O)N[C@@H](CC2=CC=CC=C2)[C@H](C[C@H](CC3=CC=CC=C3)NC(=O)[C@H](C(C)C)N4CCCNC4=O)O.CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg).
Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children.
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants.
"	C
9869929	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It obtained its FDA approval on August 17, 2011.
Option B: It first received FDA approval on April 27, 2012.
Option C: It was granted FDA approval on January 25, 2010.
Option D: It received FDA approval on February 19, 2016.
"	B
3081545	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN[C@H]1[C@H]([C@@H]2[C@H](C[C@H]([C@H](O2)O[C@@H]3[C@H](C[C@H]([C@@H]([C@H]3O)O)N)N)N)O[C@@H]1O[C@@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)N)O)O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: Not approved by FDA.
Option B: Not approved for use in humans.
Option C: Not FDA approved.
Option D: Not approved in Canada.
"	B
25137855	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCN1CC/C=C/2\\C3C=C(C=CC3SC4=CC=CC=C42)C(F)(F)F)CCO
Question about this molecule: What is the right approval information about this molecule?
Option A: It is currently not approved for use in the United States.
Option B: It is currently not approved in the United States or Canada.
Option C: Not approved for use in the United States.
Option D: It is not approved in the United States.
"	D
71657455	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
Option B: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy.
Option C: It was granted accelerated approval by the FDA in July 2018 for the treatment of relapsed of refractory acute myeloid leukemia in adults.
Option D: It was approved by the FDA in January 2021 for use in certain patients with systolic heart failure.
"	C
71731823	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in September 2014.
Option B: It was first approved by the FDA in February 2011.
Option C: It was first approved by the FDA in 2013.
Option D: It was first approved by the US FDA in November of 2018.
"	D
166548	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC=C(C=C7)O)O)O)[C@@H](C)O)C)O)O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.
Option B: It was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.
Option C: It gained approval by the Food and Drug Administration (FDA) in February 21, 2006.
Option D: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010.
"	C
16130199	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@@H](CC7=CC=CC=C7)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC8=CN=CN8)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC9=CC=C(C=C9)O)NC(=O)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA).
Option B: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.
Option C: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010.
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with:
"	A
5546	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C2=NC3=C(N=C(N=C3N=C2N)N)N
Question about this molecule: What is the right approval information about this molecule?
Option A: It was first approved for use in the U.S. by the Food and Drug Administration in 1965.
Option B: It was approved by the U.S. Food and Drug Administration on December 15, 2008.
Option C: It was approved by the Food and Drug Administration in the U.S. in 1964.
Option D: It was approved by U.S. Food and Drug Administration on August 1, 2017.
"	C
6540478	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)OC(=O)C)CCC4=C/C(=N/O)/CC[C@H]34
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 31 December 1981.
Option B: It was granted FDA approval on 29 December 1989.
Option C: It was granted FDA approval on 29 July 1948.
Option D: It was granted FDA approval on 29 December 1987.
"	B
10182969	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on September 27, 2018.
Option B: It was approved by the FDA on July 26, 2012.
Option C: It was approved by the FDA on February 25, 2015.
Option D: It was approved by the FDA on December 28, 2012.
"	D
56959087	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COCCOCCOCCOCCOCCOCCOCCO[C@H]1CC[C@]2([C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3CC=C)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in September 2014.
Option B: It was approved by the FDA in 2008.
Option C: It was approved by the FDA in January 2012.
Option D: It was approved by the FDA in December 2014.
"	A
11556711	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 26 May 2020.
Option B: The first ophthalmic solution for this molecule was granted FDA approval on August 25th 2020.
Option C: It was granted FDA Breakthrough Therapy designation in April 2015 and accelerated approval in December 2016.
Option D: FDA approved this molecule in July 2012.
"	D
31593	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)CNC(=O)CN2C=CN=C2[N+](=O)[O-]
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg) and who have taken HIV medicines in the past.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who meet specific requirements, as determined by a health care provider.
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg).
"	A
3823	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was first approved in an oral formulation for systemic use by the FDA in 1981.
Option B: It was first approved for use in the U.S. by the Food and Drug Administration in 1965.
Option C: It was first approved for use in the U.S. market in 1992, but was withdrawn shortly after.
Option D: It has been approved by FDA for use in externally applied drugs and cosmetics.
"	A
135409642	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)OCC6=C(OC(=O)O6)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in January 2012.
Option B: It was first approved by the FDA in February 2011.
Option C: It was approved by the FDA in December 2014.
Option D: It was approved by the FDA in September 2014.
"	B
53235510	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted accelerated approval by the FDA for the treatment of previously treated, unresectable locally advanced or metastatic cholangiocarcinoma in adults with a fibroblast growth factor receptor 2 (FGFR2) fusion or another rearrangement as detected by an FDA-approved test.
Option B: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout.
Option C: It was initially approved by the FDA in December, 1997 under the market name Evista® for the management and prevention of osteoporosis in postmenopausal women and reduction in risk for invasive breast cancer in postmenopausal women with osteoporosis or those who are at high risk for invasive breast cancer.
Option D: On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with unresectable or metastatic melanoma with the BRAF V600E or V600K mutations.
"	A
67505836	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CC2(CC2)C[C@H]1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)[C@@H]9[C@H]1CC[C@H](C1)N9C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved for use by the FDA in July 2015 and by Health Canada in January 2016 for the management of Cystic Fibrosis with delta-F508 mutations.
Option B: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout.
Option C: It was approved by the FDA for the treatment of HCV genotypes 1, 4, 5, and 6 with or without [ribavirin] depending on the level of liver damage or cirrhosis.
Option D: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca.
"	C
5002	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
Option B: It was first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and reduce the risk for acute urinary retention or the need for surgical procedures.
Option C: It is approved by the FDA for the treatment of schizophrenia and bipolar disorder, but frequently prescribed for off-label purposes including insomnia or the treatment of anxiety disorders.
Option D: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy.
"	C
3038522	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010.
Option B: It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for use with:
Option D: The use of it to treat AML has been granted fast-track status by the U.S. Food and Drug Administration.
"	D
4369359	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 24 April 2003.
Option B: It was granted FDA approval on October 16, 2006.
Option C: It was granted FDA approval on 31 October 1985.
Option D: It was granted FDA approval on October 31, 1986.
"	B
2789	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C(=O)CC(=O)N(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3
Question about this molecule: What is the right approval information about this molecule?
Option A: It was FDA approved on April 28, 2011.
Option B: It was FDA approved on July 31, 2009.
Option C: It was FDA approved on July 24, 2012.
Option D: The oral preparation was FDA approved on October 21, 2011.
"	D
44187	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It is currently not approved in the United States or Canada.
Option B: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States.
Option C: It is not available in the United States, but is used widely in other countries for the treatment of acute pain.
Option D: It is available in several European countries most commonly under the product name, Sulperazon.
"	D
2265	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 24 April 2003.
Option B: It was granted FDA approval on 20 April 2004.
Option C: It was granted FDA approval on 20 March 1968.
Option D: It was granted FDA approval on 13 April 1971.
"	C
208910	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1(C(=C(C(=O)O1)OCC2CC2)C3=CC=C(C=C3)S(=O)(=O)C)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It is currently not approved in the United States or Canada.
Option B: It is not approved for use in children or adolescents.
Option C: It is not FDA approved or on the market in the United States.
Option D: It is not intended or approved for use in human medicine.
"	D
64139	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
Question about this molecule: What is the right approval information about this molecule?
Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants.
Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children.
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg).
"	C
5833	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on January 21, 1960.
Option B: It was approved by the FDA on October 30, 2020.
Option C: It was approved by the FDA on May 2020.
Option D: It was approved by the FDA on December 29, 1964.
"	A
10071196	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)COC1=CC=C(C=C1)CNC(=O)N(CC2=CC=C(C=C2)F)C3CCN(CC3)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in 2008.
Option B: It was approved by the FDA in September 2014.
Option C: It was approved by the FDA in December 2014.
Option D: It was initially approved by the FDA in 2016.
"	D
3899	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Option B: It is not approved by the FDA, Health Canada, or the EMA, but it is approved in individual European countries.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children.
Option D: It is not available in the United States, but is used widely in other countries for the treatment of acute pain.
"	A
10096344	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on October 30, 2020.
Option B: It was approved by the FDA on May 2020.
Option C: It was approved by the FDA on May 16, 2018.
Option D: It was approved by the FDA on May 2, 2011.
"	D
1201549	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1[C@@H]2CC[C@H]1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on December 31, 1987.
Option B: It was first approved by the FDA on December 31, 1979.
Option C: It was officially approved by the FDA on 1996.
Option D: It was approved by the FDA on December 29, 1964.
"	C
122262	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCN1CCCN2CCN(CC2)C3=C4C=CC(=CC4=NC=C3)Cl)C5=C6C=CC(=CC6=NC=C5)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was initially approved by the FDA in April 2016.
Option B: It was initially approved by the FDA in October 2015.
Option C: It was first authorized for market by the European Medicines Agency in October 2011.
Option D: It was first approved by the FDA in February 2011.
"	C
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved in January 2016 by the FDA.
Option B: It was approved by the FDA in September 2014.
Option C: It was approved by the FDA in January 2012.
Option D: It was approved by the FDA in December 2014.
"	A
441243	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@H]([C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was initially approved by the FDA in 1991.
Option B: It was initially approved by the FDA in 1996.
Option C: It was initially approved by the FDA in 1999.
Option D: It became the first protease inhibitor approved by the FDA in 1995.
"	D
11511120	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)/C=C/CN4CCCCC4
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on June 20, 2014.
Option B: It was approved by the FDA on July 26, 2012.
Option C: It was approved by the FDA on February 25, 2015.
Option D: It was approved by the FDA on September 27, 2018.
"	D
24821094	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C=CC(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Question about this molecule: What is the right approval information about this molecule?
Option A: It was FDA-approved for the treatment of mantle cell lymphoma.
Option B: The FDA approved it for the treatment of patients with lymphangioleiomyomatosis.
Option C: It was approved by the FDA in October 2004 for the palliative treatment of this condition.
Option D: It was FDA approved in 2015 for the treatment of basal cell carcinoma.
"	A
60846	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was first approved for use in the United States in 2014.
Option B: It was approved in the United States in 1997.
Option C: It was first approved for use in the United States in 2001.
Option D: It was first approved for use in the United States in 1999.
"	B
65015	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010.
Option B: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.
Option C: It was approved by U.S. Food and Drug Administration on August 1, 2017.
Option D: It was approved by the U.S. Food and Drug Administration on December 15, 2008.
"	D
71301	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 7 December 1953.
Option B: It was granted FDA approval on 17 December 2007.
Option C: It was granted FDA approval on 5 November 2015.
Option D: It was granted FDA approval on 17 November 1997.
"	B
23652731	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in August 2014.
Option B: It was approved by the FDA in August 2019.
Option C: It was approved by the FDA in September 2014.
Option D: It was approved by the FDA in December 2014.
"	A
52918379	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 6 February 1953.
Option B: It was granted FDA approval on 14 April 1995.
Option C: It was granted FDA approval on 24 April 2003.
Option D: It was granted FDA approval on 14 February 1994.
"	C
441401	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
Question about this molecule: What is the right approval information about this molecule?
Option A: Approved by the FDA in 2013.
Option B: [tedizolid] was approved by the FDA in 2014.
Option C: It was initially approved by the FDA in 2016.
Option D: Approved by the FDA in 1977.
"	B
44603531	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)[C@H]1C(=O)N2C[C@@H](C[C@H]2C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C4CC4)OC5=NC6=C(C=CC(=C6)OC)N=C5CCCCC[C@@H]7C[C@H]7OC(=O)N1
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in January 2012.
Option B: It was approved by the FDA in December 2014.
Option C: It was approved in January 2016 by the FDA.
Option D: It was approved by the FDA in September 2014.
"	C
969472	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCN(CC1)C(=O)O[C@H]2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was first approved by the FDA on December 31, 1979.
Option B: It was approved by the FDA on December 31, 1987.
Option C: It is approved by the FDA for the long-term treatment of insomnia.
Option D: It is approved by the FDA for its veterinary use.
"	C
10629256	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@]12C=CCN3[C@@H]1[C@]4(CC3)[C@H]([C@]([C@@H]2OC(=O)C)(C(=O)OC)O)N(C5=CC(=C(C=C45)[C@]6(C[C@@H]7C[C@H](CN(C7)CC8=C6NC9=CC=CC=C89)C(C)(F)F)C(=O)OC)OC)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the European Medicines Agency (EMA) in 2009 as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment.
Option B: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout.
Option C: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca.
Option D: A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment.
"	A
57363	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and reduce the risk for acute urinary retention or the need for surgical procedures.
Option B: It was approved by the FDA in January 2021 for use in certain patients with systolic heart failure.
Option C: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy.
Option D: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
"	A
447043	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was first approved by the FDA in 1991.
Option B: It was initially approved by the FDA in 1992.
Option C: It was initially approved by the FDA in 1991.
Option D: It was initially approved by the FDA in 1999.
"	C
11567473	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)C#N)N4C[C@H]5[C@H](C4)OCCN5)F)C(=O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in January 2012.
Option B: It was approved by the FDA in September 2014.
Option C: It was approved by the FDA in December 2014.
Option D: It was approved by the FDA in 2008.
"	C
441130	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)N(C)C)C(=O)O)[C@@H](C)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved in August 2017 for treatment of adult patients with complicated urinary tract infections (cUTI).
Option B: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy.
Option C: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
Option D: It was approved by the FDA in January 2021 for use in certain patients with systolic heart failure.
"	A
60149	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCC1C2=CN(C3=C2C=C(C=C3)Cl)C4=CC=C(C=C4)F)CCN5CCNC5=O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was first approved in an oral formulation for systemic use by the FDA in 1981.
Option B: It has once again been approved and should soon be available on the French and Australian market.
Option C: It has never been approved by the FDA for clinical use.
Option D: It has been approved by FDA for use in externally applied drugs and cosmetics.
"	B
2585	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 14 April 1995.
Option B: It was granted FDA approval on 14 September 1963.
Option C: It was granted FDA approval on 14 September 1995.
Option D: It was granted FDA approval on 14 February 1994.
"	C
5487	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN=C(N1)NC2=C(C=CC3=NSN=C32)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was initially approved by the FDA in 1996.
Option B: It was approved by the FDA in 2008.
Option C: It was approved by the FDA in December 2014.
Option D: It was initially approved by the FDA in 2016.
"	A
392622	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children.
Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg).
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children.
"	A
5736	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCOC1=CC2=CC=CC=C2SC3=C1C=C(C=C3)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was initially approved by the FDA in 2016.
Option B: It was initially approved by the FDA in 1996.
Option C: It was approved by the FDA in December 2014.
Option D: It was never approved by the FDA.
"	D
135463437	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1[C@@H]2[C@@H](C([C@H]3[C@@H](O2)NC4=C(N3)C(=O)NC(=N4)N)(O)O)OP(=O)(O1)O
Question about this molecule: What is the right approval information about this molecule?
Option A: In September 2022, the EMA approved the use of fosdenopterin.
Option B: It was approved by the FDA for the treatment of trichomoniasis and bacterial vaginosis.
Option C: It was approved on March 6, 2015 by the FDA for the treatment of invasive aspergillosis and invasive mucormycosis.
Option D: It has been recently approved (late 2012) for the treatment of thrombocytopenia in patients with chronic hepatitis C.
"	A
3902	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 24 April 2003.
Option B: Letrozole was granted FDA approval on 25 July 1997.
Option C: It was granted FDA approval on 25 March 1974.
Option D: It was granted FDA approval on 26 May 2020.
"	B
208908	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy.
Option B: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
Option C: It was first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and reduce the risk for acute urinary retention or the need for surgical procedures.
Option D: It was approved by the FDA in January 2021 for use in certain patients with systolic heart failure.
"	B
4909	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC1(C(=O)NCNC1=O)C2=CC=CC=C2
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA Approval on 31 October 1949.
Option B: It was granted FDA approval on 25 March 1974.
Option C: It was granted FDA Approval on 8 March 1954.
Option D: It was granted FDA Approval on 19 December 1973.
"	C
53465279	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the European Medicines Agency (EMA) in 2009 as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment.
Option B: A combination product of bempedoic acid and [ezetimibe] was approved on February 26, 2020 for increased control of LDL cholesterol levels in patients experiencing refractory elevations despite previous statin treatment.
Option C: On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named Juluca.
Option D: In August 2017, a combination oral therapy consisting of it and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with uncontrolled gout.
"	D
10909430	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H](C)[C@H]1C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)NCCCC[C@@H](C(=O)N[C@@H](C(=O)N1)CCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSC(=N2)[C@H]([C@@H](C)CC)N)CC(=O)N)CC(=O)O)CC3=CN=CN3)CC4=CC=CC=C4
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 29 December 1989.
Option B: It was granted FDA approval on 31 December 1981.
Option C: It was granted FDA approval on 29 December 1987.
Option D: It was granted FDA approval on 29 July 1948.
"	D
148192	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children.
Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children weighing at least 4.4 lb (2 kg).
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children.
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults, children, and infants.
"	C
5311356	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OCCN6CCOCC6)O[C@H]3[C@H](C=C4)O
Question about this molecule: What is the right approval information about this molecule?
Option A: Not approved for use in the United States.
Option B: Not approved for sale in the United States or Canada.
Option C: Not approved for use in humans.
Option D: Not approved in Canada.
"	D
9829523	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: It was FDA approved on July 31, 2009.
Option B: It was approved on April 28, 2017.
Option C: It was FDA approved on January 22, 2010.
Option D: It was FDA approved on April 28, 2011.
"	B
2435	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br
Question about this molecule: What is the right approval information about this molecule?
Option A: It was FDA approved on August 2013 for the treatment of rosacea.
Option B: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia.
Option C: It was approved by the FDA in October 2004 for the palliative treatment of this condition.
Option D: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020.
"	A
6445540	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in January 2021 for use in certain patients with systolic heart failure.
Option B: It was FDA approved on October 16, 2007, for the treatment of unresponsive aggressive metastatic or locally advanced breast cancer.
Option C: It was approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy.
Option D: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
"	B
89683805	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by U.S. Food and Drug Administration on August 1, 2017.
Option B: It was approved by the U.S. Food and Drug Administration on December 15, 2008.
Option C: It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.
Option D: It was approved by the U.S. Food and Drug Administration (FDA) on June 17, 2010.
"	A
5311497	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC1=C[C@H]2C[C@@](C3=C(CN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia.
Option B: It was approved by the FDA in October 2004 for the palliative treatment of this condition.
Option C: It was initially approved in the USA in 1990's for the treatment of NSCLC.
Option D: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020.
"	C
5281078	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\\C)/CCC(=O)OCCN3CCOCC3)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted a new FDA approval in July 2019 for the treatment of oral ulcers associated with Behcet's disease.
Option B: It was granted FDA approval for the prophylaxis of transplant rejection in 1995.
Option C: It was granted FDA Breakthrough Therapy designation in April 2015 and accelerated approval in December 2016.
Option D: It was granted FDA approval for the oral contraceptive Estelle/Nextstellis.
"	B
3878	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N
Question about this molecule: What is the right approval information about this molecule?
Option A: It is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of active tuberculosis (TB).
Option B: It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and in children.
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children.
"	B
3034010	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on December 31, 1987.
Option B: It was first approved by the FDA for sale on November 25, 1997.
Option C: It is available both by prescription and over-the-counter.
Option D: It is approved by the FDA for the long-term treatment of insomnia.
"	C
60857	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on December 29, 1964.
Option B: It was first approved by the FDA on December 31, 1979.
Option C: It was first approved by the FDA for sale on November 25, 1997.
Option D: It was approved by the FDA on December 31, 1987.
"	C
42611257	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F
Question about this molecule: What is the right approval information about this molecule?
Option A: It first received FDA approval on April 27, 2012.
Option B: It received FDA approval on February 19, 2016.
Option C: It was granted FDA approval on January 25, 2010.
Option D: It obtained its FDA approval on August 17, 2011.
"	D
54682461	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC[C@]1(CC(=C(C(=O)O1)[C@H](CC)C2=CC(=CC=C2)NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)O)CCC4=CC=CC=C4
Question about this molecule: What is the right approval information about this molecule?
Option A: It is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic hepatitis C virus infection (HCV) in adults and children 3 years of age and older who meet specific requirements, as determined by a health care provider.
Option B: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who meet specific requirements, as determined by a health care provider.
Option C: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg) and who have taken HIV medicines in the past.
Option D: It is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg).
"	B
16158208	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)O)C(=O)N[C@@H](CSSC[C@@H](C(=O)N3)N)C(=O)N[C@H](C(=O)N5CCC[C@H]5C(=O)N1)CC(=O)N)CC6=CC=C(C=C6)O)CCC(=O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: FDA approved on August 30, 2012.
Option B: FDA approved on February 8, 2013.
Option C: FDA approved on August 15, 2008.
Option D: FDA approved on July 20, 2018.
"	A
159324	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=NC=C1[C@@](C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC(=CC=C5)Cl)C)N
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA Approval on 19 December 1973.
Option B: The FDA issued a Not Approvable Letter for Zarnestra.
Option C: It was granted FDA Approval on 8 March 1954.
Option D: It was granted FDA Approval on 31 October 1949.
"	B
6918456	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)OC1=CC2=C(S1)CCN(C2)C(C3=CC=CC=C3F)C(=O)C4CC4
Question about this molecule: What is the right approval information about this molecule?
Option A: FDA approved it on December 21, 2012.
Option B: FDA approved it on September 27, 2012.
Option C: FDA approved in 2009.
Option D: FDA approved on August 30, 2012.
"	C
3157	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: It was initially approved by the FDA in 1990.
Option B: It was initially approved by the FDA in 1999.
Option C: It was first approved by the FDA in 1991.
Option D: It was initially approved by the FDA in 1991.
"	A
16132283	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]([C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC7=CN=CN7)N)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was granted FDA approval on 14 November 1960.
Option B: It was granted FDA approval on 14 September 1963.
Option C: It was granted FDA approval on 14 September 1995.
Option D: It was granted FDA approval on 14 April 1995.
"	A
16134956	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC6=CN=CN6)N)C(=O)O
Question about this molecule: What is the right approval information about this molecule?
Option A: It was given FDA approval on January 21, 2011.
Option B: It first received FDA approval on April 27, 2012.
Option C: It was granted FDA approval on January 25, 2010.
Option D: It was FDA approved on April 28, 2011.
"	C
25166913	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CC[C@H](C[C@@H]1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N
Question about this molecule: What is the right approval information about this molecule?
Option A: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020.
Option B: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
Option C: It was approved by the FDA in October 2004 for the palliative treatment of this condition.
Option D: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia.
"	D
11965427	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CS(=O)(=O)C1=CC=CC(=C1)C[C@@H](C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA in October 2004 for the palliative treatment of this condition.
Option B: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020.
Option C: Approved in July, 2016 under the trade name Xiidra.
Option D: Approved by the FDA in September 2022 for ocular surface anesthesia.
"	C
5152	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
Question about this molecule: What is the right approval information about this molecule?
Option A: Granted FDA approval on 4 February 1994.
Option B: Granted FDA approval on 3 March 1965.
Option C: It was granted FDA approval on 25 March 1974.
Option D: Granted FDA approval on 25 June 1943.
"	A
115358	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=NC2=C1C(=C(C=C2NC(C)CCCN)OC)OC3=CC=CC(=C3)C(F)(F)F)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: FDA approved on July 20, 2018.
Option B: FDA approved on August 15, 2008.
Option C: FDA approved on February 8, 2013.
Option D: FDA approved on August 30, 2012.
"	A
121304016	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4
Question about this molecule: What is the right approval information about this molecule?
Option A: It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine.
Option B: Fully approved by the FDA for the treatment of COVID-19 on October 22, 2020.
Option C: It was approved by the FDA in October 2004 for the palliative treatment of this condition.
Option D: It was approved on November 21, 2018, by the FDA for the treatment of Acute Myeloid Leukemia.
"	B
6018	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1=O)OC)OC
Question about this molecule: What is the right approval information about this molecule?
Option A: FDA approved on February 8, 2013.
Option B: FDA approved on August 15, 2008.
Option C: FDA approved on August 30, 2012.
Option D: FDA approved on July 20, 2018.
"	B
208947	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C2CC[C@@H](C(=O)N2C3=CC=CC=C13)CC4=C(NC=N4)C
Question about this molecule: What is the right clinical development information about this molecule?
Option A: It is currently in clinical development for the treatment of acute myeloid leukemia (AML).
Option B: It is under clinical development for the treatment of heart failure with preserved ejection fraction.
Option C: Its clinical development was terminated in phase II.
Option D: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes.
"	C
86269973	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C(=C1)CN2C(=CC(=N2)C3=NC=C(C(=N3)NCC(C(F)(F)F)(C(F)(F)F)O)F)C4=NOC=C4)F
Question about this molecule: What is the right clinical development information about this molecule?
Option A: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women.
Option B: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011.
Option C: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes.
Option D: It is under clinical development for the treatment of heart failure with preserved ejection fraction.
"	D
6540478	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)OC(=O)C)CCC4=C/C(=N/O)/CC[C@H]34
Question about this molecule: What is the right clinical development information about this molecule?
Option A: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women.
Option B: It was developed as part of an effort to develop new hormonal contraceptives with reduced adverse effects.
Option C: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes.
Option D: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011.
"	B
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: What is the right clinical development information about this molecule?
Option A: It has been investigated in clinical trials for the treatment of heart failure in patients with diabetes.
Option B: It has been investigated in clinical trials as an alternative to classical hormone therapy to help prevent cardiovascular disease in postmenopausal women.
Option C: Follow-up clinical trials are required to validate it as a potential therapy against SARS-CoV-2.
Option D: It is under clinical development for the treatment of heart failure with preserved ejection fraction.
"	C
60857	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCC1=CNC2=C1C=C(C=C2)C[C@H]3COC(=O)N3
Question about this molecule: What is the right clinical development information about this molecule?
Option A: It is under clinical development for the treatment of heart failure with preserved ejection fraction.
Option B: It was the first triptan to be developed, but had poor oral bioavailability and lipophilicity.
Option C: It could be approved for the treatment of neurogenic orthostatic hypotension (NOH) as early as 2011.
Option D: It was developed as part of an effort to develop new hormonal contraceptives with reduced adverse effects.
"	B
39681	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)OC(=O)C(=C1SCCS1)C(=O)OC(C)C
Question about this molecule: How can the molecule be used for disease control
Option A: It is applied to vegetable, fruit and field crops; livestock; ornamental and forestry plantings; in agricultural premises and domestic settings; in greenhouses, and for control of parasites of fish in designated aquatic environments.
Option B: It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp.
Option C: It is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast.
Option D: It is an insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale.
"	D
68289416	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C2C=CC(=C(C2=N1)F)F)OC3=C(C(=CC=C3)F)C(C)(C)O
Question about this molecule: How can the molecule be used for disease control
Option A: It is applied to vegetable, fruit and field crops; livestock; ornamental and forestry plantings; in agricultural premises and domestic settings; in greenhouses, and for control of parasites of fish in designated aquatic environments.
Option B: It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp.
Option C: It is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast.
Option D: It is an insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale.
"	C
3823	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
Question about this molecule: What is the right dosage information about this molecule?
Option A: It is used in moderately high doses for severe forms of epilepsy.
Option B: It is used for long periods at high doses, especially in immunosuppressed patients.
Option C: It has been demonstrated as an efficacious treatment for vaginal yeast infections in one single dose.
Option D: It is used in high doses to prevent vaso-occlusive crises in patients with sickle cell disease.
"	B
644073	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O
Question about this molecule: What is the right dosage information about this molecule?
Option A: High doses and long term exposure can give rise to various cytotoxic and genotoxic reactions.
Option B: It is used for long periods at high doses, especially in immunosuppressed patients.
Option C: Dose titration and/or use of smaller divided doses may decrease side effects.
Option D: Use of once-daily doses may benefit individuals who have developed tolerance to other potent opioids and who require larger and more frequent doses.
"	D
5717	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=CC=C1S(=O)(=O)NC(=O)C2=CC(=C(C=C2)CC3=CN(C4=C3C=C(C=C4)NC(=O)OC5CCCC5)C)OC
Question about this molecule: What is the right dosage information about this molecule?
Option A: It is used as a single dose.
Option B: It is usually dosed twice daily.
Option C: It causes release of dopamine at higher dosages.
Option D: It is a single dose orally administered drug.
"	B
148192	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC
Question about this molecule: What is the right dosage information about this molecule?
Option A: It can be given once-daily and has lesser effects on the patient's lipid profile.
Option B: The 10 mg tablet can be taken without regard to food.
Option C: It is available in 200, 400, 600, or 800mg tablets that are taken once daily, with or without food.
Option D: It can be taken once a day due to its half-life of about 70 hours.
"	A
287180	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1C=C(C(=O)C2=C1C=C(C=C2)C3=CC=NC=C3)C(=O)O
Question about this molecule: What is the right dosage information about this molecule?
Option A: It causes release of dopamine at higher dosages.
Option B: It is usually dosed twice daily.
Option C: It is a single dose orally administered drug.
Option D: It is used as a single dose.
"	C
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: What is the right efficacy information about this molecule?
Option A: The combination product achieves a sustained virologic response (SVR) between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment.
Option B: It reduces all-cause mortality including fatal and non-fatal CVD and the need for surgical revascularization or angioplasty following a heart attack.
Option C: It has evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack.
Option D: It achieves a sustained virologic response (SVR) between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment.
"	D
44603531	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)[C@H]1C(=O)N2C[C@@H](C[C@H]2C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C4CC4)OC5=NC6=C(C=CC(=C6)OC)N=C5CCCCC[C@@H]7C[C@H]7OC(=O)N1
Question about this molecule: What is the right efficacy information about this molecule?
Option A: The combination product achieves a sustained virologic response (SVR) between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment.
Option B: It achieves a sustained virologic response (SVR) between 94% and 97% for genotype 1 and 97% and 100% for genotype 4 after 12 weeks of treatment.
Option C: It reduces all-cause mortality including fatal and non-fatal CVD and the need for surgical revascularization or angioplasty following a heart attack.
Option D: It has evidence of reducing all-cause mortality including fatal and non-fatal CVD as well as the need for surgical revascularization or angioplasty following a heart attack.
"	A
969472	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCN(CC1)C(=O)O[C@H]2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl
Question about this molecule: What is the right efficacy information about this molecule?
Option A: It demonstrates high efficacy and low toxicity, offering a safer alternative to other drugs used for insomnia.
Option B: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens.
Option C: It is approximately 10–20 times less potent than carfentanil and is the maximum strength fentanyl analog for use in humans.
Option D: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.
"	A
3559	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
Question about this molecule: What is the right efficacy information about this molecule?
Option A: Poor bioavailability limits its therapeutic efficacy.
Option B: There is only minimal evidence of efficacy for this condition.
Option C: Its efficacy was first established in controlled trials in the 1960s.
Option D: It retains its efficacy as a decongestant.
"	C
5281078	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C2COC(=O)C2=C(C(=C1OC)C/C=C(\\C)/CCC(=O)OCCN3CCOCC3)O
Question about this molecule: What is the right efficacy information about this molecule?
Option A: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.
Option B: It is approximately 10–20 times less potent than carfentanil and is the maximum strength fentanyl analog for use in humans.
Option C: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens.
Option D: It demonstrates high efficacy and low toxicity, offering a safer alternative to other drugs used for insomnia.
"	A
441383	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)N1CCN(CC1)C2=CC=C(C=C2)OC[C@H]3CO[C@](O3)(CN4C=NC=N4)C5=C(C=C(C=C5)Cl)Cl
Question about this molecule: What is the right efficacy information about this molecule?
Option A: It demonstrates an increased bioavailability, a higher efficacy, and reduced gastrointestinal effects when compared to MPA.
Option B: They have demonstrated high levels of safety, efficacy, and tolerability in clinical trials.
Option C: It has impressive efficacy, reduced risk for extrapyramidal side effects, and reduced susceptibility to drug-drug interactions.
Option D: It shows high levels of efficacy and a lack of estrogenic adverse effects when compared to older emergency contraceptive regimens.
"	B
5944	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12[C@H]3CC[C@@H]([C@@]1(C(=O)OC2=O)C)O3
Question about this molecule: How can the molecule be used for experiment
Option A: It can be used as an experimental anticancer drug that is activated in hypoxic conditions.
Option B: It can be used as an experimental drug with no known approved indications.
Option C: It can be used as an antineoplastic agent and to induce diabetes in experimental animals.
Option D: It can be used as an experimental anti-tumor agent.
"	D
1388	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCC(=CC1)C2=CC=CC=C2
Question about this molecule: How can the molecule be used for experiment
Option A: It can be used to recreate and study Parkinson's disease in experimental animal models.
Option B: It can be used as an experimental anticancer drug that is activated in hypoxic conditions.
Option C: It can be used as an antineoplastic agent and to induce diabetes in experimental animals.
Option D: It can be used as an experimental drug with no known approved indications.
"	A
135413511	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C2C(=C1)[N+](=C(N=[N+]2[O-])N)[O-]
Question about this molecule: How can the molecule be used for experiment
Option A: It can be used as an antineoplastic agent and to induce diabetes in experimental animals.
Option B: It can be used as an experimental drug with no known approved indications.
Option C: It can be used as an experimental anticancer drug that is activated in hypoxic conditions.
Option D: It can be used as a versatile experimental tool for studying pain mechanisms and for pharmacotherapy to treat some peripheral painful states.
"	C
5362449	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CC[C@]23CCCC[C@H]2[C@H]1CC4=C3C=C(C=C4)OC
Question about this molecule: How can the molecule be used for experiment
Option A: It can be used to study the cellular uptake of glucose and its potential use in diabetes.
Option B: It can be used as an experimental drug with no known approved indications.
Option C: It can be used as an antineoplastic agent and to induce diabetes in experimental animals.
Option D: It can be used to study the involvement of glutamate receptors in neurotoxicity.
"	D
86398	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=C2C(=C1)OC(O2)(F)F)C3=CNC=C3C#N
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is a fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria.
Option B: It has excellent activity against a wide range of plant pathogenic fungi, especially gray mould diseases caused by Botrytis cinerea.
Option C: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.
Option D: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases.
"	A
10403199	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It has excellent activity against a wide range of plant pathogenic fungi, especially gray mould diseases caused by Botrytis cinerea.
Option B: It is effective against Oomycete diseases such as downy mildew and certain leaf spot diseases.
Option C: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases.
Option D: It is a non-systemic fungicide widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.
"	B
136264487	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(SN=N1)C2=NNC3N2N=C(S3)C(Cl)(Cl)Cl
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is a foliar applied fungicide for cereals particularly active against Ascomycetes, Deuteromycetes and Oomycetes.
Option B: It is a fungicide with a wide spectrum of activity and inhibits the enzymatic activity of pyruvate kinase.
Option C: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases.
Option D: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.
"	B
11493665	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=CC=C1C2=C(N(N(C2=O)C(C)C)C(=O)SCC=C)N
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is used as a fungicide for the control of powdery mildew in cereal crops as well as in apple and pear orchards.
Option B: It is used for the control of Botrytis in the greenhouse cultivation of tomatoes, peppers, and cucumbers.
Option C: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes.
Option D: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.
"	B
91665	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC(=O)N2CCC3=CC=CC1=C32
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is used to control rice blast and is not approved for use within the European Union.
Option B: It is a fungicide used for the control of rice blast.
Option C: It is used for the control of rice blast in paddy fields.
Option D: It is a fungicide particularly for the control of fungal diseases in rice.
"	A
11664966	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C/C(=N\\OCC1=CC=CC=C1/C(=N\\OC)/C(=O)OC)/C2=CC(=CC=C2)C(F)(F)F
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is a foliar applied fungicide for cereals particularly active against Ascomycetes, Deuteromycetes and Oomycetes.
Option B: It has excellent activity against a wide range of plant pathogenic fungi, especially gray mould diseases caused by Botrytis cinerea.
Option C: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.
Option D: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases.
"	A
73675	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[Si](CN1C=NC=N1)(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is a fungicide used for the control of rice blast.
Option B: It is a highly toxic organomercury compound used as a fungicide for treating seeds.
Option C: It is a broad-spectrum fungicide used to protect a variety of crops.
Option D: It is a fungicide particularly for the control of fungal diseases in rice.
"	C
9796266	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C(=C1)C#N)NC(=O)C2=C(C(=NS2)Cl)Cl
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is a fungicide developed in China with high antifungal activity against specific diseases.
Option B: It is a fungicide used for the control of rice blast.
Option C: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.
Option D: It is a fungicide particularly for the control of fungal diseases in rice.
"	B
15604010	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCC1=C(N2C(=NC=N2)N=C1CC)N
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is a fungicide for use on potatoes to control late blight and downy mildew.
Option B: It is a fungicide for the control of late blight and downy mildew on potatoes and other crops.
Option C: It is a fungicide used to control Peronosporales on a range of crops including vines, hops and potatoes.
Option D: It is a fungicide used to control grey mould, downy mildew and other fungal pathogens.
"	B
18771	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C2C(=C1)C(=O)C3=C(C2=O)SC(=C(S3)C#N)C#N
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.
Option B: It is a broad-spectrum fungicide used to control scab, downy mildew, rust, and leaf spot in the commercial growing of grapes and other fruit, citrus, coffee, and vegetables.
Option C: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases.
Option D: It has excellent activity against a wide range of plant pathogenic fungi, especially gray mould diseases caused by Botrytis cinerea.
"	B
2804318	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)NC(=O)C2=C(N=NS2)C)Cl
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It is used for the treatment of a range of fungal diseases in rice.
Option B: It is a fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.
Option C: It is a non-systemic fungicide widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.
Option D: It is a fungicide particularly for the control of fungal diseases in rice.
"	D
68289416	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C2C=CC(=C(C2=N1)F)F)OC3=C(C(=CC=C3)F)C(C)(C)O
Question about this molecule: Which kind of fungicide is this molecule?
Option A: It has excellent activity against a wide range of plant pathogenic fungi, especially gray mould diseases caused by Botrytis cinerea.
Option B: It is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast.
Option C: It prevents spore germination and mycelial growth of sensitive fungi and is used in agriculture for the control of various fungal diseases.
Option D: It is a fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts.
"	B
12056760	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C(=NN(C1=O)C(=O)[N-]S(=O)(=O)C2=CC=CC=C2OC(F)(F)F)OC.[Na+]
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is used as a herbicide to control grass weeds in cereal crops.
Option B: It is used for control of grass weeds in cereal crops.
Option C: It is used as a post-emergence herbicide to control weeds in various cereal crops.
Option D: It is used as a herbicide for the control of annual grass weeds in cereal crops.
"	A
92425	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is used as a herbicide for the control of a variety of both annual and perennial weeds in crops, particularly wheat and rice.
Option B: It is used for the control of annual weeds in cereal crops, maize, and rice.
Option C: It is used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes.
Option D: It is used for the control of weeds in soya, peanuts, and a variety of vegetable and fruit crops.
"	D
11714234	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=C1C(=O)N(C(=O)O1)C2=CC(=C(C=C2F)Cl)OC3CCCC3)C
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is used as a pre- or post-emergence herbicide for the control of annual and perennial weeds in rice.
Option B: It is used as a post-emergence herbicide for the control of annual weeds in crops.
Option C: It is used as a pre- and post-emergence herbicide to control weeds in rice.
Option D: It is used as a post-emergence herbicide to control weeds in various cereal crops.
"	C
153920	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C1=NN(C(=O)N1N)C(=O)NC(C)(C)C
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is a selective herbicide for pre- and post-emergence control of annual dicotyledonous weeds and grasses.
Option B: It is used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations.
Option C: It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of fruit and root crops.
Option D: It is used as a pre- and post-emergent herbicide for the treatment of grasses and broad-leaved weeds in rice crops.
"	A
11188745	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COCCOCC1=C(C=CC(=N1)C(F)(F)F)C(=C2C(=O)[C@@H]3CC[C@@H](C3)C2=O)O
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is used as a pre- and post-emergence herbicide to control weeds in rice.
Option B: It is used for the pre- and post-emergence control of weeds in corn.
Option C: It is used as a pre- or post-emergence herbicide for the control of annual and perennial weeds in rice.
Option D: It is used for the post-emergence control of weeds in rice, grass, and turf.
"	B
134692036	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)C(=O)C1=CC(=CC=C1)NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is used as a pre- and post-emergent herbicide for the treatment of grasses and broad-leaved weeds in rice crops.
Option B: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops.
Option C: It is used as a herbicide for the control of a variety of broad-leaved and sedge weeds in paddy fields and other aquatic situations.
Option D: It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of fruit and root crops.
"	A
3294375	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is used as a herbicide for the control of broad-leaved weeds in cereal crops.
Option B: It is used as a herbicide to control broad-leaved weeds in soya and tobacco crops.
Option C: It is used for the control of broad-leaved weeds in crops such as maize and soya.
Option D: It is used as herbicide for the control of broad-leaved weeds in peanuts, soya beans, and other crops.
"	A
92383	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=NN(C(=C1C(=O)C2=C(C=C(C=C2)Cl)Cl)OCC(=O)C3=CC=CC=C3)C
Question about this molecule: How can the molecule be used as a/an herbicide
Option A: It is used as a post-emergence herbicide for the control of annual weeds in crops.
Option B: It is used as a pre- or post-emergence herbicide for the control of annual and perennial weeds in rice.
Option C: It is used as a post-emergence herbicide to control weeds in various cereal crops.
Option D: It is used as a pre- and post-emergence herbicide to control weeds in rice.
"	B
73672	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC
Question about this molecule: Which kind of herbicide is this molecule?
Option A: It is an herbicide from the benzamide family intended for use in vineyards and tree nut orchards for the preemergence control of broadleaf weeds.
Option B: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf.
Option C: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops.
Option D: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds.
"	A
86429	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)N(C1=CC=C(C=C1)F)C(=O)COC2=NN=C(S2)C(F)(F)F
Question about this molecule: Which kind of herbicide is this molecule?
Option A: It is a thiadiazole herbicide applied to the soil surface or incorporated preemergence in field corn, corn grown for silage, or soybeans to control certain annual grasses and broadleaf weeds.
Option B: It is an imine herbicide that is applied to actively growing weeds in soybeans to control annual broadleaf weeds, and is particularly effective in controlling velvetleaf.
Option C: It is a selective systemic phenoxy herbicide used to control many annual and perennial broadleaf weeds in alfalfa, peanuts, soybeans, and other crops.
Option D: It is a triazine herbicide and is used as a pre- and post-emergent herbicide to control annual grasses and broadleaf weeds.
"	A
84098	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3
Question about this molecule: Which kind of herbicide is this molecule?
Option A: It is an herbicide and algicide used in water treatment.
Option B: It is used as a herbicide for weed control in wheat.
Option C: It is an isoxazole herbicide that is approved for use on field corn.
Option D: It is an herbicide used to kill weeds on land and in the water.
"	C
2265	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
Question about this molecule: Which kind of immunosuppressive agent is this molecule?
Option A: It displays immunosuppresive and anti-angiogenic activity.
Option B: It is effective both as an anticancer and an immunosuppressive agent, and is used to treat leukemia and autoimmune diseases as a corticosteroid-sparing agent.
Option C: It is an immunosuppressive pro-drug.
Option D: It is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties.
"	C
11635141	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1CC2=CC(=C(C(=C2C3=C(C4=C(C=C3[C@@H]([C@@H]1C)OC(=O)/C=C/C5=CC=CC=C5)OCO4)OC)O)OC)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an HIV protease inhibitor.
Option B: It is a HIV-1 protease inhibitor.
Option C: It is a HIV-1 integrase inhibitor.
Option D: It is a HIV-1 reverse transcriptase inhibitor.
"	A
70697730	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C([C@H]([C@H]2[C@@H](C1)OC(=O)C2=C)O)[C@H](C)CCCOC(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nitrification inhibitor.
Option B: It is a nitric oxide synthase inhibitor.
Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option D: It is a protein synthesis inhibitor.
"	C
57398143	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12CCC(=O)OC([C@@H]1CC[C@]3([C@H]2C[C@@]4(C(=C)[C@]3(C(=O)[C@@](C4=O)(C)O)C(=O)OC)C)C)(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a protease inhibitor.
Option B: It is an HIV protease inhibitor.
Option C: It is a HIV-1 protease inhibitor.
Option D: It is a cysteine protease inhibitor.
"	D
11470243	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1CC2=C(O1)C3=C(C(=CC=C3)O)C(=O)C2=O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor.
Option B: It is an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor.
Option C: It is an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor and an EC 3.1.3.1 (alkaline phosphatase) inhibitor.
Option D: It is an EC 3.1.3.1 (alkaline phosphatase) inhibitor.
"	A
10509987	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1[C@H]2[C@@H](C3=C4[C@@H]([C@H](OC4=CC(=C3)O)C5=CC=C(C=C5)O)C6=C2C(=CC(=C6)O)O)[C@H]7[C@@H](C8=C(C=C(C=C8O)O)[C@@H]9[C@H](OC1=CC(=CC7=C91)O)C1=CC=C(C=C1)O)C1=CC=C(C=C1)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor.
Option B: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option C: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option D: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor.
"	B
9997028	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1CC[C@@]2([C@@H]([C@@]1(C)CCC3CCOC3=O)CCC=C2C(=O)O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclooxygenase 2 inhibitor.
Option B: It is a cyclooxygenase inhibitor.
Option C: It is a lipoxygenase inhibitor.
Option D: It is a cyclooxygenase 1 inhibitor.
"	C
25181189	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]\\1C[C@@H](OC(=O)C[C@@H](NC(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@H](C/C(=C1)/C)C)C)C)CC(=O)C2=CC=CC=C2N)C3=CC=C(C=C3)O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an HIV fusion inhibitor.
Option B: It is an actin polymerisation inhibitor.
Option C: It is an actin assembly inhibitor.
Option D: It is an HIV protease inhibitor.
"	B
9846431	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC[C@@H]2CCN3CCC[C@@H]([C@@H]3O2)CCCCCC[C@@H]4CCN5CCC[C@H]([C@@H]5O4)CC1
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an IP3 receptor antagonist.
Option B: It is a selective serotonin reuptake inhibitor (SSRI).
Option C: It is a selective serotonin receptor antagonist.
Option D: It is a serotonin uptake inhibitor.
"	A
70680259	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@H]2C3=CC[C@H]4[C@]([C@@]3(CC[C@]2(CCC1=C)C(=O)O)C)(CC[C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)OC(=O)/C=C/C6=CC=C(C=C6)O)O)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.1.3 (triacylglycerol lipase) inhibitor.
Option B: It is a triacylglycerol lipase inhibitor.
Option C: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor and an EC 3.1.1.3 (triacylglycerol lipase) inhibitor.
Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor.
"	B
6437368	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(CCC1)(C)C)CC/C(=C/CCC2=CC[C@@H](O[C@H]2O)C3=CC(=O)O[C@H]3O)/C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a phospholipase A2 inhibitor.
Option B: It is a phospholipase A2 (PLA2) inhibitor.
Option C: It is an EC 3.1.1.4 (phospholipase A2) inhibitor.
Option D: It is an inhibitor of phospholipase A2.
"	A
53344646	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C[C@@H]([C@](CC1)(C)/C=C/C2=C(C=CC(=C2)C3=COC4=CC(=CC(=C4C3=O)O)O)O)C5=C(C=CC(=C5)C6=COC7=CC(=CC(=C7C6=O)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.5.1.23 (ceramidase) inhibitor.
Option B: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
Option C: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor.
Option D: It is a beta-glucuronidase inhibitor.
"	D
16681402	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C2=C(C=C1[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COC(=O)C4=CC(=C(C(=C4)O)O)O)O)O)O)C(=O)OC5=C(C=C(C(=C5O)OC)[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)COC(=O)C7=CC(=C(C(=C7)O)O)O)O)O)O)C(=O)O2)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a retroviral ribonuclease H inhibitor.
Option B: It is a ribonucleotide reductase inhibitor.
Option C: It is an EC 3.1.26.13 (retroviral ribonuclease H) inhibitor.
Option D: It is an EC 3.1.27.3 (ribonuclease T1) inhibitor.
"	A
70678745	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@@H](C(=O)N[C@H](C(=O)C(=O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)O1)C)CC(=O)N)CC(C)C)CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)CC3=CC=CC=C3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 protease inhibitor.
Option B: It is a leukocyte elastase inhibitor.
Option C: It is a protease inhibitor.
Option D: It is a cysteine protease inhibitor.
"	B
23651847	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1CSCC2=CC=C(C=C2)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an oral histone deacetylase inhibitor and antineoplastic agent.
Option B: It is an inhibitor of histone deacetylase (HDAC).
Option C: It is an EC 3.5.1.98 (histone deacetylase) inhibitor.
Option D: It is a histone deacetylase inhibitor.
"	D
3084224	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C2=C3C(=C1)C=CN=C3C(=O)C4=CC5=C(C=C42)OCO5)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor.
Option B: It is an acetylcholinesterase inhibitor.
Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor.
Option D: It is an acetylcholinesterase (AChE) inhibitor.
"	B
54686377	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CCCC([C@@]12CC3=C4C2=C(C=C(C4=C(C5=C3[C@@H]([C@]6(CC(=O)C(=C([C@]6(C5=O)O)O)C(=O)N)O)O)O)O)OC)(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nitric oxide synthase inhibitor.
Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option C: It is a ditrans,polycis-undecaprenyl-diphosphate synthase inhibitor.
Option D: It is an inositol phosphorylceramide synthase inhibitor.
"	C
10502865	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)O[C@H]1C[C@@H]2C[C@]3([C@@H]1[C@@]4([C@H](C[C@@H](C([C@H]4C(=O)C3)(C)C)OC(=O)C)O)C)C(=O)C2=C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 protease inhibitor.
Option B: It is an aromatase inhibitor.
Option C: It is a protease inhibitor.
Option D: It is an HIV protease inhibitor.
"	B
449094	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C[C@H]2C(=O)N[C@H](C(=O)N2C1)CC3=CN=CN3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a glutamine synthetase inhibitor.
Option B: It is a dopamine uptake inhibitor.
Option C: It is a tropane-based dopamine inhibitor.
Option D: It is a histamine-1 receptor inhibitor.
"	B
500428	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1OC2=C(O1)C3=C(C=C2)C(=O)C4=NC=CC5=CC6=C(C3=C54)OCO6
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an HIV protease inhibitor.
Option B: It is a HIV-1 reverse transcriptase inhibitor.
Option C: It is a HIV-1 integrase inhibitor.
Option D: It is a HIV-1 protease inhibitor.
"	C
25258213	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1C[C@H]2CC(=O)O[C@@]3(C1)[C@@]24CCCN3CCCC4=O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor.
Option B: It is an acetylcholinesterase (AChE) inhibitor.
Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor.
Option D: It is an acetylcholinesterase inhibitor.
"	D
445114	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OP(=O)(N[C@@H](CC(C)C)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)O)O)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a neprilysin inhibitor.
Option B: It is a nitrification inhibitor.
Option C: It is a tyrosinase inhibitor.
Option D: It is a protease inhibitor.
"	A
11090783	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1CC[C@H]2[C@]13CC[C@@]4([C@H](C3)[C@@H]([C@]2(O4)C)NCCCCN(C)CCCN(C)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a phosphoinositide phospholipase C inhibitor.
Option B: It is an EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor.
Option C: It is a phospholipase A2 (PLA2) inhibitor.
Option D: It is a phospholipase A2 inhibitor.
"	A
5311105	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=C(C=C1/C=C/2\\C=C(OC2=O)C3=CC(=C(C=C3)O)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosine kinase inhibitor.
Option B: It is a tyrosine kinase receptor inhibitor.
Option C: It is a selective tyrosine kinase receptor inhibitor.
Option D: It is a specific tyrosine kinase receptor inhibitor.
"	A
71306327	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1[C@@H]2[C@H]([C@H]([C@H](O2)C3=CC=C(C=C3)O)C4=CC5=C(C=C4O)O[C@H]([C@@H]5C6=CC(=CC(=C6)O)O)C7=CC=C(C=C7)O)C8=CC(=CC(=C8)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a DNA topoisomerase (ATP-hydrolysing) inhibitor.
Option B: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option C: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor.
Option D: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
"	A
24939147	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C=C1CC[C@@H]2[C@@H]([C@@H]3[C@H]1CC(=O)[C@]34CC[C@]5([C@@]4(C[C@@H]6[C@H]5[C@@H]7[C@@H](CCC6=C)C(=C)C(=O)O7)O)O)OC(=O)C2=C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option B: It is a protein synthesis inhibitor.
Option C: It is a nitric oxide synthase inhibitor.
Option D: It is a nitrification inhibitor.
"	A
25256841	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1CC(=O)O[C@H]1[C@]2(CC(=O)C3=C(O2)C=CC(=C3O)C4=C5C(=C(C=C4C)O)C(=O)C[C@@](O5)(C)[C@H]6[C@@H](CC(=O)O6)O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a P450 inhibitor.
Option B: It is a protein synthesis inhibitor.
Option C: It is a Hsp90 inhibitor.
Option D: It is a thrombin inhibitor.
"	A
5270	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC(OC1)N2C=NC3=C(N=CN=C32)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.11.1.6 (catalase) inhibitor.
Option B: It is an EC 3.5.1.2 (glutaminase) inhibitor.
Option C: It is an EC 3.5.1.5 (urease) inhibitor.
Option D: It is an EC 4.6.1.1 (adenylate cyclase) inhibitor.
"	D
11527348	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=CC(=C1)C(=O)OCC2=CC(=C(C=C2)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)COC(=O)/C=C/C4=CC(=C(C=C4)O)O)O)O)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor and an EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor.
Option B: It is an EC 1.4.3.22 (diamine oxidase) inhibitor and an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor.
Option C: It is an EC 3.4.21.37 (leukocyte elastase) inhibitor and an EC 3.4.21.64 (peptidase K) inhibitor.
Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor and an EC 3.1.1.3 (triacylglycerol lipase) inhibitor.
"	D
52940771	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C/C/1=C\\CC[C@@]2([C@@H](O2)CC(/C=C/C1=O)(C)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option B: It is a nitric oxide synthase inhibitor.
Option C: It is a nitrification inhibitor.
Option D: It is a protein synthesis inhibitor.
"	A
29307	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOP(=S)(OCC)OC1=NOC(=C1)C2=CC=CC=C2
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor.
Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor.
Option C: It is an acetylcholinesterase inhibitor.
Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor.
"	B
60198	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)C=C[C@]34C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a selective inhibitor of the aromatase (oestrogen synthase) system.
Option B: It is a nonsteroidal inhibitor of aromatase.
Option C: It is an aromatase inhibitor.
Option D: It is a steroidal inhibitor of aromatase.
"	A
5281401	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H]1CN2CC[C@@]34[C@@H]2C[C@@H]1[C@H]5[C@@H]3N([C@@H](OC5)[C@@H]([C@H]\\6C[C@H]7C8=C(CCN7C/C6=C/C)C9=CC=CC=C9N8)C(=O)OC)C1=CC=CC=C41
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor.
Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor.
Option C: It is an acetylcholinesterase inhibitor.
Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor.
"	B
70697741	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12CC[C@]3(CC(=O)C(C=C3[C@H]1CC[C@H]4[C@]2(CC[C@@H]5[C@@]4(CCC(=O)C5(C)C)C)C)(C)C)C(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosine kinase inhibitor.
Option B: It is a tyrosine kinase receptor inhibitor.
Option C: It is an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor.
Option D: It is a selective tyrosine kinase receptor inhibitor.
"	C
5481969	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=CC1C2=C(C3=C(O1)C=C(C=C3)O)OC4=C(C2=O)C(=CC5=C4C=CC(O5)(C)C)O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a moderate inhibitor of acetylcholinesterase and a strong inhibitor of platelet-activating factor induced platelet aggregation.
Option B: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1.
Option C: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease.
Option D: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease.
"	A
5481969	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=CC1C2=C(C3=C(O1)C=C(C=C3)O)OC4=C(C2=O)C(=CC5=C4C=CC(O5)(C)C)O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an acetylcholinesterase inhibitor, a platelet aggregation inhibitor, and a tyrosinase inhibitor.
Option B: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease.
Option C: It is a moderate inhibitor of acetylcholinesterase and a strong inhibitor of platelet-activating factor induced platelet aggregation.
Option D: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1.
"	A
11308672	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC(=CC(=C1O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)OC)[C@@H]3[C@H]([C@@H](CC4=CC(=C(C(=C34)OC)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)OC)CO)CO
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a lipoxygenase inhibitor.
Option B: It is a cyclooxygenase inhibitor.
Option C: It is a cyclooxygenase 1 inhibitor.
Option D: It is a cyclooxygenase 2 inhibitor.
"	A
25058097	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1O)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COC(=O)C3=CC(=C(C(=C3)O)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C(=C5)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.27.3 (ribonuclease T1) inhibitor.
Option B: It is a retroviral ribonuclease H inhibitor.
Option C: It is an EC 3.1.26.13 (retroviral ribonuclease H) inhibitor.
Option D: It is a ribonucleotide reductase inhibitor.
"	B
118796903	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](/C=C/S(=O)(=O)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)CN3CCOCC3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a selective proteasome inhibitor.
Option B: It is a HIV-1 protease inhibitor.
Option C: It is a protease inhibitor.
Option D: It is an HIV protease inhibitor.
"	A
159269	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN(C(=O)NC1=O)[C@@H]2C[C@H]([C@@H](O2)CO)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.7.6 (RNA polymerase) inhibitor.
Option B: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor.
Option C: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor.
Option D: It is an EC 3.5.1.5 (urease) inhibitor.
"	C
44587245	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)N(C)C(=O)C5=CC=CC=C5)C)C)NC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.1.8 (cholinesterase) inhibitor.
Option B: It is an acetylcholinesterase inhibitor and a cholinesterase inhibitor.
Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor.
Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 2.5.1.18 (glutathione transferase) inhibitor.
"	A
54767916	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)NC2=CC=C(C=C2)[C@@H]3CC[C@H](N3C4=CC=C(C=C4)C(C)(C)C)C5=CC=C(C=C5)NC(=O)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nonnucleoside hepatitis C virus polymerase inhibitor.
Option B: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor.
Option C: It is a hepatitis C virus nonstructural protein 5A inhibitor.
Option D: It is a hepatitis C protease inhibitor.
"	C
34698	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O[C@H]6[C@@H]([C@H]([C@H]7[C@H](O6)COC(O7)C8=CC=CS8)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option B: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor.
Option C: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option D: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor.
"	C
12056760	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C(=NN(C1=O)C(=O)[N-]S(=O)(=O)C2=CC=CC=C2OC(F)(F)F)OC.[Na+]
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an acetolactate synthase inhibitor.
Option B: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor.
Option C: It is an EC 1.11.1.6 (catalase) inhibitor.
Option D: It is an ATP synthase inhibitor.
"	B
9568614	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C(N2)C=C(C=C3)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor.
Option B: It is an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Option C: It is an EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor.
Option D: It is an EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor.
"	D
4235	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1COCCN1CCNC(=O)C2=CC=C(C=C2)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a reversible monoamine oxidase inhibitor.
Option B: It is a monoamine oxidase inhibitor.
Option C: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor).
Option D: It is a specific, reversible inhibitor of monoamine oxidase A.
"	A
11837140	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=C(SC(=N1)SC2=NN=C(S2)N)[N+](=O)[O-]
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclin-dependent kinase inhibitor.
Option B: It is a c-Jun N-terminal kinase inhibitor.
Option C: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
Option D: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor.
"	B
1474853	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OC4=CC=CC=C4)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a competitive dual site (both the ATP- and peptide-binding) Src kinase inhibitor.
Option B: It is a mitogen-activated protein kinase inhibitor.
Option C: It is a potent protein kinase C inhibitor.
Option D: It is a potent, selective, and cell-permeable protein kinase C inhibitor.
"	A
1474853	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OC4=CC=CC=C4)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option B: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
Option C: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
Option D: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
"	C
10182969	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.4.21.6 (coagulation factor Xa) inhibitor.
Option B: It is an oral anticoagulant and direct inhibitor of factor Xa.
Option C: It is an oral anticoagulant and direct factor Xa inhibitor.
Option D: It is a direct inhibitor of thrombin and anticoagulant.
"	A
65399	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C2=NC=NC3=C2C(=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)C(=N1)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
Option B: It is an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor.
Option C: It is a phosphatidylinositol 3-kinase inhibitor.
Option D: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor.
"	B
447874	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC2=C(C=C(C=N2)C3=CC=C(C=C3)O)C4=C1C=CN=C4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
Option B: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor.
Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option D: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.
"	D
121490161	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1([C@@H]2CC[C@]1(C(=O)C2)CS(=O)(=O)O)C.CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)N2
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor.
Option B: It is an EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor.
Option C: It acts as a NAD(+) ADP-ribosyltransferase inhibitor.
Option D: It is an EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor.
"	A
92425	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor.
Option B: It is a reversible monoamine oxidase inhibitor.
Option C: It acts as a protoporphyrinogen oxidase inhibitor.
Option D: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor).
"	A
1549120	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C/C(=C\\C1=CC=CC=C1)/C=C\\2/C(=O)N(C(=S)S2)CC(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor.
Option B: It is an EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor.
Option C: It is an EC 1.1.1.21 (aldehyde reductase) inhibitor.
Option D: It is an EC 1.11.1.6 (catalase) inhibitor.
"	C
91885989	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=CC2=C1N=C(N2C)NC3=C(C=C(C=C3)F)F)OC4=CC(=NC=C4)NC(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
Option B: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
Option C: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option D: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
"	B
3081367	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C(=NN(C1=O)C(=O)NS(=O)(=O)C2=CC=CC=C2OC(F)(F)F)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor.
Option B: It is an acetolactate synthase inhibitor.
Option C: It is an ATP synthase inhibitor.
Option D: It is an EC 1.11.1.6 (catalase) inhibitor.
"	A
24997615	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F.CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F.O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.
Option B: It is a sodium-dependent Pi-transporter inhibitor and a HIV-1 reverse transcriptase inhibitor.
Option C: It is a sodium-glucose transport protein subtype 2 inhibitor.
Option D: It is a sodium-glucose cotransporter 2 inhibitor.
"	C
11714234	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=C1C(=O)N(C(=O)O1)C2=CC(=C(C=C2F)Cl)OC3CCCC3)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a reversible monoamine oxidase inhibitor.
Option B: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor).
Option C: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor.
Option D: It acts as a protoporphyrinogen oxidase inhibitor.
"	C
56675920	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CSC1=CC=C(C=C1)C2=CC3=C(S2)C(=NC=N3)SCC(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
Option B: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option C: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
Option D: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
"	B
9799506	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1(C(CC2=C(C(=C(C=C2O1)OC)C(=O)/C=C/C3=CC=C(C=C3)O)O)O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nitrification inhibitor.
Option B: It is a protein synthesis inhibitor.
Option C: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option D: It is a nitric oxide synthase inhibitor.
"	C
10296883	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
Option B: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option C: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.
Option D: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor.
"	B
10280735	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.4.21.6 (coagulation factor Xa) inhibitor.
Option B: It is an inhibitor of factor Xa.
Option C: It is an oral anticoagulant and direct inhibitor of factor Xa.
Option D: It is an oral anticoagulant and direct factor Xa inhibitor.
"	A
54717251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=COC(=C1)C/C(=C/C/C=C(\\C)/C(C)C2=C(C3=C(C=C(C=C3)OC)OC2=O)O)/C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nitric oxide synthase inhibitor.
Option B: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option C: It is an EC 1.14.18.1 (tyrosinase) inhibitor.
Option D: It is an EC 1.14.14.14 (aromatase) inhibitor.
"	B
136264487	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(SN=N1)C2=NNC3N2N=C(S3)C(Cl)(Cl)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
Option B: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option C: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
Option D: It is a pyruvate kinase inhibitor.
"	C
25178184	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=CCC1=C2C(=C3C(=C1O)C(=O)C(=C(O3)C4=CC(=C(C=C4)C[C@@H](C(=C)C)O)O)O)CCC(O2)(C)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor.
Option B: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
Option C: It is an EC 3.5.1.23 (ceramidase) inhibitor.
Option D: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor.
"	D
2179	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=CC(=C1)NS(=O)(=O)C)NC2=C3C=CC=CC3=NC4=CC=CC=C42
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor.
Option B: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option C: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor.
Option D: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
"	D
11526671	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(=O)C1=CSC(=N1)NC(=O)[C@H]([C@@H](C)C2=CC=CC=C2)N3C(=O)[C@H](NC3=O)C4=CC=C(C=C4)OCCO
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.10 (IkappaB kinase) inhibitor.
Option B: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor.
Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option D: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.
"	D
4993	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor.
Option B: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor.
Option C: It is an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor.
Option D: It inhibits the enzyme dihydrofolate reductase.
"	A
10366136	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of type III tyrosine kinases, PDGFRalpha/beta and FLT3.
Option B: It is a dual tyrosine kinase inhibitor (TKI) of epithelial growth factor receptors (EGFR) HER2 and HER3.
Option C: It is an oral tyrosine kinase inhibitor selective for vascular endothelial growth factor (VEGF) receptors -1, -2 and -3.
Option D: It is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor.
"	A
60153192	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C2C[C@@H](CCC(=C2CC1=O)CO)C(=C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option B: It is a nitric oxide synthase inhibitor.
Option C: It is a nitrification inhibitor.
Option D: It is a protein synthesis inhibitor.
"	A
1935	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC2=NC3=CC=CC=C3C(=C2C1)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor.
Option B: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor.
Option C: It is an acetylcholinesterase inhibitor.
Option D: It is an EC 3.1.1.8 (cholinesterase) inhibitor.
"	B
9909587	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCCC1=COC2(C1=O)CC(C(O2)(CC(=O)O)C(=O)O)C(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 4.2.1.1 (carbonic anhydrase) inhibitor.
Option B: It is an EC 1.11.1.6 (catalase) inhibitor.
Option C: It is an EC 3.5.1.5 (urease) inhibitor.
Option D: It is an EC 3.2.1.166 (heparanase) inhibitor.
"	D
10014426	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CN=C1)/C=C/C2=CNC3=C2C=CC(=C3)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.13.11.11 (tryptophan 2,3-dioxygenase) inhibitor.
Option B: It is an EC 2.5.1.9 (riboflavin synthase) inhibitor.
Option C: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor.
Option D: It is an EC 1.11.1.6 (catalase) inhibitor.
"	A
5090	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclooxygenase 2 inhibitor.
Option B: It is a cyclooxygenase 1 inhibitor.
Option C: It is a cyclooxygenase inhibitor.
Option D: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor.
"	A
91826547	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(C)(C)C1=CC=C(C=C1)CC(C)C[NH+]2C[C@H](O[C@H](C2)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.166 (heparanase) inhibitor.
Option B: It is an EC 3.4.21.5 (thrombin) inhibitor.
Option C: It is a cholestenol Delta-isomerase inhibitor.
Option D: It is an EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor.
"	D
54677470	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a competitive inhibitor.
Option B: It is a selective COX-2 inhibitor.
Option C: It is a COX-2 inhibitor.
Option D: It is a CDK7 inhibitor.
"	C
589075	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CC=C3F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an HIV fusion inhibitor.
Option B: It is an actin assembly inhibitor.
Option C: It is an actin polymerisation inhibitor.
Option D: It is an HIV protease inhibitor.
"	B
54676038	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C2C(=C1)C(=C(C(=O)O2)CC3=C(C4=CC=CC=C4OC3=O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a competitive inhibitor.
Option B: It is a vitamin K antagonist.
Option C: It is a beta-adrenergic antagonist.
Option D: It is a mitotic inhibitor.
"	B
3010818	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a hepatitis C protease inhibitor.
Option B: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor.
Option C: It is a nonnucleoside hepatitis C virus polymerase inhibitor.
Option D: It is a hepatitis C virus nonstructural protein 5A inhibitor.
"	A
44591583	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a sterol biosynthesis inhibitor.
Option B: It is a thrombin inhibitor.
Option C: It is a phosphodiesterase inhibitor.
Option D: It is a phosphodiesterase IV inhibitor.
"	D
11790	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C4=CC=CC=C4C=C3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor.
Option B: It is an EC 1.14.14.14 (aromatase) inhibitor.
Option C: It is an EC 1.11.1.6 (catalase) inhibitor.
Option D: It is an EC 1.14.18.1 (tyrosinase) inhibitor.
"	B
3277	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1C2=NC=C(C(=C2C=N1)NN=C(C)C)C(=O)OCC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a sterol biosynthesis inhibitor.
Option B: It is a thrombin inhibitor.
Option C: It is a phosphodiesterase IV inhibitor.
Option D: It is a phosphodiesterase inhibitor.
"	C
134692036	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)C(=O)C1=CC(=CC=C1)NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an ATP synthase inhibitor.
Option B: It is an EC 2.2.1.6 (acetolactate synthase) inhibitor.
Option C: It is an EC 1.11.1.6 (catalase) inhibitor.
Option D: It is an acetolactate synthase inhibitor.
"	B
51351746	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H](C)[C@H]1C(=O)NC(C(=O)N[C@H](C(=O)N([C@H](C(=O)N2CCC[C@H]2C(=O)N[C@@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)O1)C(C)C)C)CC(C)C)C(C)C)C)[C@H](C)C(C)C)CC3=CC=CC=C3)C)CC4=CC=CC=C4)C(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of glucosylceramide synthase.
Option B: It is an inositol phosphorylceramide synthase inhibitor.
Option C: It is an inhibitor of phospholipase A2.
Option D: It is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.
"	B
16214946	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCN(CC1)C2CC(C2)C3=NC(=C4N3C=CN=C4N)C5=CC6=C(C=C5)C=CC(=N6)C7=CC=CC=C7
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a potent, reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases.
Option B: It is a small molecular inhibitor of Raf kinase, PDGF (platelet-derived growth factor), VEGF receptor 2 & 3 kinases and c Kit the receptor for Stem cell factor.
Option C: It inhibits insulin growth factor 1 receptor (IGF-1 receptor, IGFR1R) tyrosine kinase.
Option D: It is an oral tyrosine kinase inhibitor selective for vascular endothelial growth factor (VEGF) receptors -1, -2 and -3.
"	C
5494425	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
Option B: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option C: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
Option D: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
"	C
11960529	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It acts as a NAD(+) ADP-ribosyltransferase inhibitor.
Option B: It is an EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor.
Option C: It is an EC 2.3.1.24 (sphingosine N-acyltransferase) inhibitor.
Option D: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor.
"	D
17755052	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor.
Option B: It is a phosphatidylinositol 3-kinase inhibitor.
Option C: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor.
Option D: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
"	A
4521392	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a selective tyrosine kinase receptor inhibitor.
Option B: It is a tyrosine kinase inhibitor.
Option C: It is a tyrosine kinase receptor inhibitor.
Option D: It is an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor.
"	D
91699	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir).
Option B: It is a small molecule inhibitor of the If ion channel which is used to decrease the heart rate in patients with symptomatic heart failure who have a resting heart rate above 70 beats per minute despite optimal doses or intolerance of beta blockers.
Option C: It is a sterol demethylation inhibitor.
Option D: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease.
"	C
21631107	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12C[C@@]3([C@@H]4C[C@]1([C@@]4([C@H](O2)O3)COC(=O)C5=CC=C(C=C5)O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)COC(=O)C7=CC=CC=C7)O)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosinase inhibitor.
Option B: It is a tyrosine kinase receptor inhibitor.
Option C: It is a tyrosine-kinase inhibitor.
Option D: It is a tyrosine kinase inhibitor.
"	A
70678772	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCC(=O)N[C@@H](C(C)C)C(=O)N[C@H]1[C@H](OC(=O)[C@@H](NC(=O)[C@@H](N(C(=O)[C@@H](N2[C@@H](CC[C@H](C2=O)NC(=O)[C@@H](NC1=O)CCCCN)O)[C@H](C)CC)C)CC3=CC(=C(C=C3)OC)Br)C(C)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a potent inhibitor.
Option B: It is a mitotic inhibitor.
Option C: It is a trypsin inhibitor.
Option D: It is a competitive inhibitor.
"	C
5312122	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a potent protein kinase C inhibitor.
Option B: It is a mitogen-activated protein kinase inhibitor.
Option C: It is a cGMP-dependent protein kinase inhibitor.
Option D: It is a Ca(2+)/calmodulin-dependent protein kinase inhibitor.
"	D
11648928	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1C[C@H]2C(=C(C1)C[C@H]3CCC[C@H](N3)CC4=C5CCCN([C@H]5C[C@H](C4)C)C(=O)C)CCCN2C(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an acetylcholinesterase (AChE) inhibitor.
Option B: It is an acetylcholinesterase inhibitor.
Option C: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor.
Option D: It is an EC 3.1.1.7 (acetylcholinesterase) inhibitor and an EC 3.1.1.8 (cholinesterase) inhibitor.
"	B
4174	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor.
Option B: It is an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor.
Option C: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor.
Option D: It is an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor.
"	C
5287539	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)N1C(=O)C(=C(N1)C2=C(C=C(C=C2)Cl)Cl)C(=O)C3=C(C=C(C=C3)S(=O)(=O)C)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor.
Option B: It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor.
Option C: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor.
Option D: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor.
"	B
914268	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC2=C([C@H](C1)C(=O)N)NC3=C2C=C(C=C3)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a SIRT1 inhibitor.
Option B: It is a CDK7 inhibitor.
Option C: It is a trypsin inhibitor.
Option D: It is a memapsin 2 inhibitor.
"	A
45266500	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)NO)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)OCC2=CC=CC=C2
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a matrix metalloproteinase inhibitor.
Option B: It is a leukocyte elastase inhibitor.
Option C: It is a metalloendopeptidase inhibitor.
Option D: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor.
"	C
25920884	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)OC2=CC=CC=C2NC(=O)NC3=CC=CC(=C3)C4=CNC5=C4C=C(C=N5)C6=CC=C(C=C6)CN
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor.
Option B: It is a tyrosine kinase receptor inhibitor.
Option C: It is a selective tyrosine kinase receptor inhibitor.
Option D: It is a tyrosine kinase inhibitor.
"	A
16130199	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@@H](CC7=CC=CC=C7)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC8=CN=CN8)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC9=CC=C(C=C9)O)NC(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 protease inhibitor.
Option B: It is a HIV-1 integrase inhibitor.
Option C: It is an HIV protease inhibitor.
Option D: It is an HIV fusion inhibitor.
"	D
23582824	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC2=NC=CC(=C2C=C1/C=C\\3/C(=O)NC(=O)S3)C4=CC=NC=C4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a phosphatidylinositol 3-kinase inhibitor.
Option B: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor.
Option C: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
Option D: It is an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor.
"	D
64139	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 protease inhibitor.
Option B: It is a HIV-1 reverse transcriptase inhibitor.
Option C: It is a HIV-1 integrase inhibitor.
Option D: It is an HIV protease inhibitor.
"	B
44584621	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C/C(=C\\CO)/CC[C@@H]1C(=C)C[C@H]([C@@H]2[C@@]1(CCC[C@@]2(C)C(=O)O)C)OC(=O)C3=CC=CC=C3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.18 (exo-alpha-sialidase) inhibitor.
Option B: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
Option C: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor.
Option D: It is an EC 3.5.1.23 (ceramidase) inhibitor.
"	B
25062766	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
Option B: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option C: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
Option D: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
"	D
16129704	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H](C)[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CC(C)C)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CC(=O)N)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@@H](CC6=CC=CC=C6)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.11.1.6 (catalase) inhibitor.
Option B: It is an EC 3.4.21.5 (thrombin) inhibitor.
Option C: It is an EC 3.5.1.5 (urease) inhibitor.
Option D: It is an EC 3.5.1.2 (glutaminase) inhibitor.
"	B
5464386	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC(=C2C(=C1)OC3=C(C=C(C(=C3C2=O)O)C4=C5C(=C(C(=C4O)[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)O)C(=O)C=C(O5)C7=CC(=C(C=C7)O)O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option B: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor.
Option C: It is an EC 6.5.1.1 [DNA ligase (ATP)] inhibitor.
Option D: It is an EC 5.99.1.2 (DNA topoisomerase) inhibitor.
"	C
442119	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC2=C(C=C1Cl)NC3=C2C=C(S3)C(=O)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.14.13.39 (nitric oxide synthase) inhibitor.
Option B: It is a nitrification inhibitor.
Option C: It is a nitric oxide synthase inhibitor.
Option D: It is a protein synthesis inhibitor.
"	A
3034010	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor.
Option B: It is a triacylglycerol lipase inhibitor.
Option C: It is an EC 3.2.1.20 (alpha-glucosidase) inhibitor and an EC 3.1.1.3 (triacylglycerol lipase) inhibitor.
Option D: It is an EC 3.1.1.3 (triacylglycerol lipase) inhibitor.
"	D
213053	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C(C=C1)C2=C(N=CN2C3=CC=C(C=C3)S(=O)(=O)N)Cl)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclooxygenase 2 inhibitor.
Option B: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor.
Option C: It is a cyclooxygenase inhibitor.
Option D: It is a cyclooxygenase 1 inhibitor.
"	A
10200651	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)C2=NN=C(O2)C)C3=CC=C(C=C3)C(=O)NC4=CC=CC(=C4)C#N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
Option B: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor.
Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option D: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.
"	D
24821094	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C=CC(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option B: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
Option C: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
Option D: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
"	C
2372	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=CC=C1)OCC(CNCCC2=CC(=C(C=C2)OC)OC)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a mitotic inhibitor.
Option B: It is a vitamin K antagonist.
Option C: It is a beta-adrenergic antagonist.
Option D: It is a competitive inhibitor.
"	C
119326	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1C=C[C@H]2CCCC[C@H]2[C@@H]1C3=CC(=C(C(=O)O3)C=O)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor.
Option B: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor.
Option C: It is an EC 2.7.7.6 (RNA polymerase) inhibitor.
Option D: It is an EC 3.5.1.5 (urease) inhibitor.
"	A
208910	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1(C(=C(C(=O)O1)OCC2CC2)C3=CC=C(C=C3)S(=O)(=O)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclooxygenase 2 inhibitor and a cyclooxygenase 1 inhibitor.
Option B: It is a cyclooxygenase 2 inhibitor.
Option C: It is a cyclooxygenase inhibitor.
Option D: It is a cyclooxygenase 1 inhibitor.
"	B
3294375	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.11.1.6 (catalase) inhibitor.
Option B: It is an EC 1.11.1.6 (catalase) inhibitor and a carotenoid biosynthesis inhibitor.
Option C: It is a carotenoid biosynthesis inhibitor.
Option D: It is an EC 2.5.1.9 (riboflavin synthase) inhibitor.
"	C
78161839	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C1=C2N=C(N=C(N2N=C1)NCC3=CC=CC=C3N4C=CC=N4)OC5CCCNC5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a CDK7 inhibitor.
Option B: It is a competitive inhibitor.
Option C: It is a potent inhibitor.
Option D: It is a mitotic inhibitor.
"	A
5335	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)N2C(=CC=N2)NS(=O)(=O)C3=CC=C(C=C3)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a potent, selective, and cell-permeable protein kinase C inhibitor.
Option B: It is a P-glycoprotein and CYP3A4 inhibitor.
Option C: It is a potent protein kinase C inhibitor.
Option D: It is a cytochrome P450 (CYP) 2C9 isozyme inhibitor.
"	D
90488788	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CC(=O)O)NC(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.4.22.53 (calpain-2) inhibitor.
Option B: It is an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor.
Option C: It is an EC 3.4.21.37 (leukocyte elastase) inhibitor and an EC 3.4.21.64 (peptidase K) inhibitor.
Option D: It is an EC 3.4.22.52 (calpain-1) inhibitor and an EC 3.4.22.53 (calpain-2) inhibitor.
"	D
5330949	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H](C1=CC=C(C=C1)N2CCCC2=O)C(=O)NC3=NNC(=C3)C4CC4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclin dependent kinase inhibitor.
Option B: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
Option C: It is a cyclin-dependent kinase inhibitor.
Option D: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
"	B
47641	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C/C=C/C1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.14.13.132 (squalene monooxygenase) inhibitor.
Option B: It is an EC 1.14.17.1 (dopamine beta-monooxygenase) inhibitor.
Option C: It is an EC 1.14.16.2 (tyrosine 3-monooxygenase) inhibitor.
Option D: It is a steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor.
"	A
159324	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=NC=C1[C@@](C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC(=CC=C5)Cl)C)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It acts as a NAD(+) ADP-ribosyltransferase inhibitor.
Option B: It is an EC 2.5.1.58 (protein farnesyltransferase) inhibitor.
Option C: It is an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor.
Option D: It is an EC 2.5.1.117 (homogentisate solanesyltransferase) inhibitor.
"	B
54682461	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC[C@]1(CC(=C(C(=O)O1)[C@H](CC)C2=CC(=CC=C2)NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)O)CCC4=CC=CC=C4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 reverse transcriptase inhibitor.
Option B: It is an HIV protease inhibitor.
Option C: It is a HIV-1 integrase inhibitor.
Option D: It is a HIV-1 protease inhibitor.
"	B
21310926	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN(CC)CC1=CC(=C(C(=C1)C)N(CC2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)OC)C(=O)NO
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35) inhibitor.
Option B: It is a neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11) inhibitor.
Option C: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor.
Option D: It is a metalloendopeptidase inhibitor.
"	A
5326869	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1COCCN1C2=CC(=CC(=C2)C(=O)NC3=CC4=C(C=C3)C=CN4CCC5=CC=NC=C5)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
Option B: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor.
Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option D: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.
"	D
92727	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(=CC=C1)C)OCC(=O)N[C@@H](CC2=CC=CC=C2)[C@H](C[C@H](CC3=CC=CC=C3)NC(=O)[C@H](C(C)C)N4CCCNC4=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 protease inhibitor.
Option B: It is an HIV protease inhibitor.
Option C: It is a protease inhibitor.
Option D: It is a HIV-1 integrase inhibitor.
"	C
10089048	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)C(=O)NC2CC2)C3=C(C=C(C=C3)C4=NN=C(O4)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option B: It is an EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor.
Option C: It is an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.
Option D: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
"	C
44603531	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)[C@H]1C(=O)N2C[C@@H](C[C@H]2C(=O)N[C@@]3(C[C@H]3C=C)C(=O)NS(=O)(=O)C4CC4)OC5=NC6=C(C=CC(=C6)OC)N=C5CCCCC[C@@H]7C[C@H]7OC(=O)N1
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nonnucleoside hepatitis C virus polymerase inhibitor.
Option B: It is a hepatitis C virus nonstructural protein 5A inhibitor.
Option C: It is a hepatitis C protease inhibitor.
Option D: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor.
"	C
5323714	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1COC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-]
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor.
Option B: It is an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor.
Option C: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor.
Option D: It is an EC 1.4.3.4 (monoamine oxidase) inhibitor.
"	D
443380	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COCCOC[C@H](CC1(CCCC1)C(=O)NC2CCC(CC2)C(=O)O)C(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.4.24.* (metalloendopeptidase) inhibitor.
Option B: It is a matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35) inhibitor.
Option C: It is a metalloendopeptidase inhibitor.
Option D: It is a neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11) inhibitor.
"	D
24891645	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COCCNC(=O)C1=CC=C(C=C1)NC2=NC=C3C=C(C=CC3=N2)C4=CC=NC=C4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an AKT1 kinase inhibitor.
Option B: It is a potent protein kinase C inhibitor.
Option C: It is a mitogen-activated protein kinase inhibitor.
Option D: It is a B-Raf and MKNK2 kinase inhibitor.
"	D
16220188	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a potent inhibitor of MAPK.
Option B: It is a potent inhibitor.
Option C: It is a mitotic inhibitor.
Option D: It is a competitive inhibitor.
"	A
42619	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC2=C(C(=NN2C)C)C(=O)C3=C(C=C(C=C3)Cl)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor.
Option B: It is an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor.
Option C: It is an EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor.
Option D: It is a 4-hydroxyphenylpyruvate dioxygenase inhibitor.
"	C
148121	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor.
Option B: It inhibits the enzyme dihydrofolate reductase.
Option C: It is an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor.
Option D: It is an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an EC 2.1.2.2 (phosphoribosylglycinamide formyltransferase) inhibitor.
"	A
449193	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a thrombin inhibitor.
Option B: It is a phosphodiesterase inhibitor.
Option C: It is a sterol biosynthesis inhibitor.
Option D: It is a phosphodiesterase IV inhibitor.
"	D
5328779	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
Option B: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
Option C: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option D: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
"	A
49867926	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
Option B: It is a phosphatidylinositol 3-kinase inhibitor.
Option C: It is an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor.
Option D: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor.
"	C
68498031	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN=C(C=N1)C(=O)N[C@H]2CCCCC/C=C\\[C@H]3C[C@]3(NC(=O)[C@@H]4C[C@H](CN4C2=O)OC5=NC6=CC=CC=C6C7=CC=CC=C75)C(=O)NS(=O)(=O)C8CC8
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nonnucleoside hepatitis C virus polymerase inhibitor.
Option B: It is a hepatitis C protease inhibitor.
Option C: It is a hepatitis C virus nonstructural protein 5A inhibitor.
Option D: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor.
"	B
73729049	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1CN(CCN1C2=NC=C(C=C2)C#N)C3=NN=C(C4=C3C=C(C=C4)Cl)CC5=CC=CC=C5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 4.1.2.27 (sphinganine-1-phosphate aldolase) inhibitor.
Option B: It is an EC 1.14.18.1 (tyrosinase) inhibitor.
Option C: It is an EC 1.14.14.14 (aromatase) inhibitor.
Option D: It is an EC 1.11.1.6 (catalase) inhibitor.
"	A
503535	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=C(C=C1)C(=O)N(C2=C(SC(=C2)C3=CC=CC=C3)C(=O)O)C(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor.
Option B: It is an EC 2.7.7.6 (RNA polymerase) inhibitor.
Option C: It is an EC 1.11.1.6 (catalase) inhibitor.
Option D: It is an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor.
"	B
49830468	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CC(=O)NC1=NNC2=C1C=C(C=C2)C3=CN(N=N3)CC4=CC=CC=C4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.1.33 (pantothenate kinase) inhibitor.
Option B: It is an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor.
Option C: It is an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor.
Option D: It is an EC 2.7.1.40 (pyruvate kinase) inhibitor.
"	C
10435235	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[C@H](C4=CC(=CC(=C4)F)F)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a protease inhibitor.
Option B: It is a kinase inhibitor.
Option C: It is a tyrosinase inhibitor.
Option D: It is a gamma-secretase inhibitor.
"	D
2352168	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)NCC3=CC=CC=N3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a mitogen-activated protein kinase inhibitor.
Option B: It is a potent protein kinase C inhibitor.
Option C: It is a kinase inhibitor.
Option D: It is a dual-kinase inhibitor.
"	A
11638999	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1CC[C@@H]2[C@](CCCC2(C)C)(C3=C1OC4=C(C(=C(C=C34)O)O)C=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.2.1.31 (beta-glucuronidase) inhibitor.
Option B: It is a phosphatidylinositol 3-kinase inhibitor.
Option C: It is an EC 2.4.1.17 (glucuronosyltransferase) inhibitor.
Option D: It is an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor.
"	B
71657455	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an orally available small molecule inhibitor of isocitrate dehydrogenase.
Option B: It is an inhibitor of isocitrate dehydrogenase 2.
Option C: It is an inhibitor of carbonic anhydrase, particularly subtypes II and IV.
Option D: It is an isocitrate dehydrogenase inhibitor.
"	D
5479543	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N)NC(=O)[C@H](CC2=CC=CC=C2)C[C@H]([C@H](CC3=CC=CC=C3)NC(=O)OC(C)(C)C)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a mitotic inhibitor.
Option B: It is a memapsin 2 inhibitor.
Option C: It is a CDK7 inhibitor.
Option D: It is a trypsin inhibitor.
"	B
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a hepatitis C virus nonstructural protein 5A inhibitor.
Option B: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor.
Option C: It is a hepatitis C protease inhibitor.
Option D: It is a nonnucleoside hepatitis C virus polymerase inhibitor.
"	A
72735810	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCC1=CC=C(C=C1)C(=O)N2CCC(CC2)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosine kinase inhibitor.
Option B: It is a sphingosine kinase inhibitor.
Option C: It is a tyrosine kinase receptor inhibitor.
Option D: It is a selective tyrosine kinase receptor inhibitor.
"	B
5330286	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclin-dependent kinase inhibitor.
Option B: It is a cyclin dependent kinase inhibitor.
Option C: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
Option D: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
"	A
49831143	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C(=O)N(C(=O)N(C1=S)C)C2=CC3=C(C=C2F)OC(C(=O)N3CC#C)(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor).
Option B: It is a reversible monoamine oxidase inhibitor.
Option C: It acts as a protoporphyrinogen oxidase inhibitor.
Option D: It is an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor.
"	D
5092	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.5.1.5 (urease) inhibitor.
Option B: It is an EC 3.1.1.4 (phospholipase A2) inhibitor.
Option C: It is an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor.
Option D: It is an EC 3.5.1.4 (amidase) inhibitor.
"	C
44591583	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: B1(C2=C(CO1)C=C(C=C2)OC3=CC=C(C=C3)C#N)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a Phosphodiesterase 5 Inhibitor.
Option B: It is a Phosphodiesterase 4 Inhibitor.
Option C: It is a P-Glycoprotein Inhibitor.
Option D: It is a Cholinesterase Inhibitor.
"	B
16222096	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCN[C@@H](C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a multi-specific tyrosine kinase receptor inhibitor.
Option B: It is a tyrosine kinase receptor inhibitor.
Option C: It is a specific tyrosine kinase receptor inhibitor.
Option D: It is a selective tyrosine kinase receptor inhibitor.
"	B
9869929	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCC[C@H]4CO)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a Phosphodiesterase 4 Inhibitor.
Option B: It is a Phosphodiesterase 5 Inhibitor.
Option C: It is a P-Glycoprotein Inhibitor.
Option D: It is a Cholinesterase Inhibitor.
"	B
71657455	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of cysteine proteinases.
Option B: It is an inhibitor of cellular mitosis.
Option C: It is an isocitrate dehydrogenase inhibitor.
Option D: It is an inhibitor of isocitrate dehydrogenase 2.
"	D
71731823	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosine kinase receptor inhibitor.
Option B: It is a receptor protein-tyrosine kinase inhibitor.
Option C: It is a tyrosine kinase inhibitor.
Option D: It is a selective tyrosine kinase receptor inhibitor.
"	D
16130199	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC5=CNC6=CC=CC=C65)C(=O)N[C@@H](CC7=CC=CC=C7)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC8=CN=CN8)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC9=CC=C(C=C9)O)NC(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an HIV protease inhibitor.
Option B: It is a HIV-1 integrase inhibitor.
Option C: It is an HIV fusion inhibitor.
Option D: It is a HIV-1 reverse transcriptase inhibitor.
"	C
3010818	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nonnucleoside hepatitis C virus polymerase inhibitor.
Option B: It is an inhibitor of the hepatitis C virus (HCV) RNA polymerase.
Option C: It inhibits the NS5A region of the hepatitis C virus (HCV).
Option D: It is an oral, direct acting hepatitis C virus (HCV) protease inhibitor.
"	D
5318	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1CSC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma.
Option B: It is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes.
Option C: It is an inhibitor of collagen formation used to treat idiopathic pulmonary fibrosis.
Option D: It is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis.
"	B
10182969	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=CC=C(C=C1)N2C3=C(CCN(C3=O)C4=CC=C(C=C4)N5CCCCC5=O)C(=N2)C(=O)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a direct inhibitor of thrombin and anticoagulant.
Option B: It is an inhibitor of cellular mitosis.
Option C: It is an oral anticoagulant and direct inhibitor of factor Xa.
Option D: It is an oral anticoagulant and direct factor Xa inhibitor.
"	C
213053	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C(C=C1)C2=C(N=CN2C3=CC=C(C=C3)S(=O)(=O)N)Cl)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a competitive inhibitor.
Option B: It is a COX-2 inhibitor.
Option C: It is a selective COX-2 inhibitor.
Option D: It is a CDK7 inhibitor.
"	C
11556711	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an oral selective BCL-2 inhibitor and antineoplastic agent.
Option B: It is an oral histone deacetylase inhibitor and antineoplastic agent.
Option C: It is an irreversible proteasome inhibitor and antineoplastic agent.
Option D: It is an antineoplastic enzyme inhibitor.
"	C
54767916	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C(=O)NC2=CC=C(C=C2)[C@@H]3CC[C@H](N3C4=CC=C(C=C4)C(C)(C)C)C5=CC=C(C=C5)NC(=O)[C@@H]6CCCN6C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of NS5A.
Option B: It is an inhibitor of cellular mitosis.
Option C: It is an inhibitor of neuronal activity.
Option D: It is an inhibitor of unwanted bacteria.
"	A
53235510	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN1CCN(CC1)C2=CC=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosine kinase receptor inhibitor.
Option B: It is a selective tyrosine kinase receptor inhibitor.
Option C: It is a receptor protein-tyrosine kinase inhibitor.
Option D: It is a FGF receptor kinase inhibitor.
"	D
60198	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC(=C)C4=CC(=O)C=C[C@]34C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nonsteroidal inhibitor of aromatase.
Option B: It is a steroidal inhibitor of aromatase.
Option C: It is an aromatase inhibitor.
Option D: It is a selective inhibitor of the aromatase (oestrogen synthase) system.
"	B
3108	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of platelet aggregation.
Option B: It is an inhibitor of NS5A.
Option C: It is a platelet aggregation inhibitor.
Option D: It is an inhibitor of cellular mitosis.
"	A
60947	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCS(=O)(=O)N[C@@H](CC1=CC=C(C=C1)OCCCCC2CCNCC2)C(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of platelet aggregation.
Option B: It is an inhibitor of NS5A.
Option C: It is a platelet aggregation inhibitor.
Option D: It is an inhibitor of cellular mitosis.
"	C
4369359	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor.
Option B: It is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
Option C: It is a prolyl oligopeptidase inhibitor.
Option D: It is an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
"	B
18283	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a first generation nucleoside analogue and reverse transcriptase inhibitor.
Option B: It is a nucleoside analogue and reverse transcriptase inhibitor.
Option C: It is a nucleoside reverse transcriptase inhibitor.
Option D: It is a reverse transcriptase inhibitor.
"	A
16129706	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]([C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)CC5=CC=CC=C5)CC(=O)N)CCCCN)NC(=O)CNC(=O)[C@H](C)N)C(=O)O)CO)[C@@H](C)O)CC6=CC=CC=C6)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a neprilysin inhibitor.
Option B: It is a tyrosinase inhibitor.
Option C: It is a long-acting dopamine agonist and prolactin inhibitor.
Option D: It is a long-acting analogue of somatostatin.
"	D
4235	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1COCCN1CCNC(=O)C2=CC=C(C=C2)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA).
Option B: It is a reversible monoamine oxidase inhibitor.
Option C: It is a specific, reversible inhibitor of monoamine oxidase A.
Option D: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor).
"	A
64139	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a nucleoside reverse transcriptase inhibitor.
Option B: It is a first generation nucleoside analogue and reverse transcriptase inhibitor.
Option C: It is a nucleoside analogue and reverse transcriptase inhibitor.
Option D: It is a nonnucleoside reverse transcriptase inhibitor.
"	D
65999	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCC1=NC2=C(N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C=C(C=C2C)C5=NC6=CC=CC=C6N5C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an angiotensin-converting enzyme (ACE) inhibitor.
Option B: It is an angiotensin converting enzyme (ACE) inhibitor.
Option C: It is an angiotensin II receptor blocker used in the therapy of hypertension.
Option D: It is an angiotensin II receptor blocker.
"	D
3899	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a pyrimidine synthesis inhibitor.
Option B: It is a protein synthesis inhibitor.
Option C: It is a sterol biosynthesis inhibitor.
Option D: It acts as a DNA synthesis inhibitor.
"	A
10096344	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
Option B: It is a prolyl oligopeptidase inhibitor.
Option C: It is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
Option D: It is an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor.
"	C
5090	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a cyclooxygenase inhibitor.
Option B: It is a cyclooxygenase 1 inhibitor.
Option C: It is a selective cyclooxgenase-2 (Cox-2) inhibitor.
Option D: It is a cyclooxygenase 2 inhibitor.
"	C
1201549	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1[C@@H]2CC[C@H]1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a trypsin inhibitor.
Option B: It is a tropane-based dopamine inhibitor.
Option C: It is a histamine-1 receptor inhibitor.
Option D: It is a dopamine uptake inhibitor.
"	B
4101	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1N2CN3CN1CN(C2)C3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of cellular mitosis.
Option B: It is an inhibitor of bacterial growth.
Option C: It is an inhibitor of NS5A.
Option D: It is an inhibitor of unwanted bacteria.
"	D
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of neuronal activity.
Option B: It is an inhibitor of unwanted bacteria.
Option C: It is an inhibitor of cellular mitosis.
Option D: It is an inhibitor of NS5A.
"	D
441243	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@H]([C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(=O)N)NC(=O)C4=NC5=CC=CC=C5C=C4)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an HIV protease inhibitor.
Option B: It is a HIV-1 integrase inhibitor.
Option C: It is a protease inhibitor.
Option D: It is a HIV-1 protease inhibitor.
"	C
3827	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a trypsin inhibitor.
Option B: It is a dopamine uptake inhibitor.
Option C: It is a tropane-based dopamine inhibitor.
Option D: It is a histamine-1 receptor inhibitor.
"	D
9568614	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C(N2)C=C(C=C3)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a proton pump inhibitor.
Option B: It is a protein synthesis inhibitor.
Option C: It is a competitive inhibitor.
Option D: It is a potent inhibitor.
"	A
11511120	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)/C=C/CN4CCCCC4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a kinase inhibitor.
Option B: It is a dual-kinase inhibitor.
Option C: It is a multi-kinase inhibitor.
Option D: It is a multi-kinase receptor inhibitor.
"	D
24821094	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C=CC(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosine kinase inhibitor.
Option B: It is a tyrosine kinase receptor inhibitor.
Option C: It is an inhibitor of Bruton’s tyrosine kinase.
Option D: It is a selective tyrosine kinase receptor inhibitor.
"	C
9651	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CC[C@@]23C=C[C@@H](C[C@@H]2OC4=C(C=CC(=C34)C1)OC)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a Neuraminidase Inhibitor.
Option B: It is a Cholinesterase Inhibitor.
Option C: It is a P-Glycoprotein Inhibitor.
Option D: It is an Intestinal Lipase Inhibitor.
"	B
10280735	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]3C[C@H](CC[C@@H]3NC(=O)C(=O)NC4=NC=C(C=C4)Cl)C(=O)N(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a CDK7 inhibitor.
Option B: It is a competitive inhibitor.
Option C: It is a mitotic inhibitor.
Option D: It is a Factor Xa inhibitor.
"	D
41774	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease.
Option B: It is an alpha glucosidase inhibitor which decreases intestinal absorption of carbohydrates and is used as an adjunctive therapy in the management of type 2 diabetes.
Option C: It is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity used in the therapy of gastroesophageal reflux and peptic ulcer disease.
Option D: It is a calcineurin inhibitor and potent immunosuppressive agent used largely as a means of prophylaxis against cellular rejection after transplantation.
"	B
54676038	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C2C(=C1)C(=C(C(=O)O2)CC3=C(C4=CC=CC=C4OC3=O)O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of cellular mitosis.
Option B: It is an inhibitor of neuronal activity.
Option C: It is used in biochemical experiments as an inhibitor of reductases.
Option D: It is an inhibitor of NS5A.
"	C
5352062	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C/C=C\\1/C(=O)N[C@H](C(=O)O[C@H]\\2CC(=O)N[C@@H](C(=O)N[C@H](CSSCC/C=C2)C(=O)N1)C(C)C)C(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor.
Option B: It is a proteasome inhibitor and antineoplastic agent used in the treatment of refractory multiple myeloma and certain lymphomas.
Option C: It is an intravenously administered histone deacetylase inhibitor and antineoplastic agent that is approved for use in refractory or relapsed cutaneous and peripheral T cell lymphomas.
Option D: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma.
"	C
23652731	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of cellular mitosis.
Option B: It is an inhibitor of glucosylceramide synthase.
Option C: It is an inhibitor of the influenza neuraminidase enzyme.
Option D: It is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.
"	D
449193	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a Phosphodiesterase 4 Inhibitor.
Option B: It is a P-Glycoprotein Inhibitor.
Option C: It is a Phosphodiesterase 5 Inhibitor.
Option D: It is a Cholinesterase Inhibitor.
"	A
1935	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC2=NC3=CC=CC=C3C(=C2C1)N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a Neuraminidase Inhibitor.
Option B: It is a P-Glycoprotein Inhibitor.
Option C: It is an Intestinal Lipase Inhibitor.
Option D: It is a Cholinesterase Inhibitor.
"	D
57363	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C(=O)NC(C)(C)C)CC[C@@H]4[C@@]3(C=CC(=O)N4)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a protease inhibitor.
Option B: It is a glutamine synthetase inhibitor.
Option C: It is a ribonucleotide reductase inhibitor.
Option D: It is a 5-alpha reductase inhibitor.
"	D
5330286	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor.
Option B: It is a cyclin dependent kinase inhibitor.
Option C: It is a cyclin-dependent kinase inhibitor.
Option D: It is an EC 2.7.11.13 (protein kinase C) inhibitor.
"	C
10275777	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)C(=N)C1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)OC)C(=O)NC3=NC=C(C=C3)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a direct inhibitor of thrombin and anticoagulant.
Option B: It is an oral anticoagulant and direct factor Xa inhibitor.
Option C: It is an inhibitor of cellular mitosis.
Option D: It is an oral anticoagulant and direct inhibitor of factor Xa.
"	D
11664966	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C/C(=N\\OCC1=CC=CC=C1/C(=N\\OC)/C(=O)OC)/C2=CC(=CC=C2)C(F)(F)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a potent inhibitor.
Option B: It is a competitive inhibitor.
Option C: It is a respiration inhibitor.
Option D: It is a mitotic inhibitor.
"	C
2541	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an angiotensin-converting enzyme (ACE) inhibitor.
Option B: It is an angiotensin II receptor blocker used in the therapy of hypertension.
Option C: It is an angiotensin II receptor blocker.
Option D: It is an angiotensin converting enzyme (ACE) inhibitor.
"	C
392622	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 integrase inhibitor.
Option B: It is a HIV-1 reverse transcriptase inhibitor.
Option C: It is an HIV protease inhibitor.
Option D: It is a HIV-1 protease inhibitor.
"	D
656583	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC[C@]45[C@@]3(CC(=C([C@H]4O5)O)C#N)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
Option B: It is an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor.
Option C: It is a 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor.
Option D: It is an EC 1.1.1.159 (7alpha-hydroxysteroid dehydrogenase) inhibitor.
"	A
25074470	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N)NC(=O)[C@@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma.
Option B: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma.
Option C: It is a potent inhibitor of the synthesis of testosterone (in men) and estrogen (in women) and is used to treat advanced prostate cancer.
Option D: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor.
"	C
40632	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN(C(=O)C=C1)C2=CC=CC=C2
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of collagen formation used to treat idiopathic pulmonary fibrosis.
Option B: It is an orally available tyrosine kinase receptor antagonist that inhibits collagen formation and is used to treat idiopathic pulmonary fibrosis.
Option C: It is a selective inhibitor of BRAF kinase that is used in the therapy of patients with metastatic and advanced malignant melanoma.
Option D: It is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinson’s disease.
"	A
11625818	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H](C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an oral kinase inhibitor approved for use in combination with rituximab in relapsed or refractory chronic lymphocytic leukemia (CLL) and as monotherapy for relapsed follicular B cell, small lymphocytic lymphoma and indolent non-Hodgkin lymphoma.
Option B: It is an inhibitor of platelet aggregation that is used to decrease the risk of further cardiovascular thrombotic events in patients with a history of myocardial infarction or peripheral vascular disease.
Option C: It is an oral, small molecule inhibitor of the mitogen activated protein kinase 1 and 2 (MEK1/2) used to treat symptomatic, refractory fibromas in neurofibromatosis type 1.
Option D: It is an oral, small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, psoriatic arthritis and inflammatory bowel disease.
"	A
5281037	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)/C=C(\\CC3=CC=CS3)/C(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an angiotensin-converting enzyme (ACE) inhibitor.
Option B: It is an angiotensin II receptor blocker.
Option C: It is an angiotensin II receptor blocker used in the therapy of hypertension.
Option D: It is an angiotensin converting enzyme (ACE) inhibitor.
"	C
3902	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a non-steroidal aromatase inhibitor used for the adjuvant treatment of hormonally-responsive breast cancer.
Option B: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor.
Option C: It was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
Option D: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma.
"	A
208908	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a tyrosine kinase receptor inhibitor that is used in the therapy of advanced or metastatic pancreatic or non-small cell lung cancer.
Option B: It is a small molecule inhibitor of several tyrosine kinase receptors involved in tumor cell growth used in the therapy of advanced breast cancer and other solid tumors.
Option C: It is a tyrosine kinase receptor inhibitor and antineoplastic agent used in the therapy of selected forms of advanced non-small cell lung cancer.
Option D: It is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of advanced non-small cell lung cancer (NSCLC).
"	B
53465279	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a selective serotonin reuptake inhibitor (SSRI).
Option B: It is a selective inhibitor of uric acid reabsorption.
Option C: It is a selective serotonin reuptake inhibitor (SSRI) and partial serotonin receptor agonist.
Option D: It is a serotonin and norepinephrine reuptake inhibitor.
"	B
92727	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C(=CC=C1)C)OCC(=O)N[C@@H](CC2=CC=CC=C2)[C@H](C[C@H](CC3=CC=CC=C3)NC(=O)[C@H](C(C)C)N4CCCNC4=O)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a potent inhibitor.
Option B: It is a potent protein kinase C inhibitor.
Option C: It is a potent inhibitor of the enzymes responsible for this molecule metabolism.
Option D: It is a potent inhibitor of MAPK.
"	C
49803313	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an orally available small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3).
Option B: It is an inhibitor of type III tyrosine kinases, PDGFRalpha/beta and FLT3.
Option C: It inhibits insulin growth factor 1 receptor (IGF-1 receptor, IGFR1R) tyrosine kinase.
Option D: It is a dual tyrosine kinase inhibitor (TKI) of epithelial growth factor receptors (EGFR) HER2 and HER3.
"	A
68844	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCN[C@H]1CN(S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)CCCOC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a specific, reversible inhibitor of monoamine oxidase A.
Option B: It is a nonhydrazine monoamine oxidase inhibitor (MAO inhibitor).
Option C: It is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor.
Option D: It is a reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA).
"	C
148192	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C)[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN(CC2=CC=C(C=C2)C3=CC=CC=N3)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O)NC(=O)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a HIV-1 integrase inhibitor.
Option B: It is a HIV-1 protease inhibitor.
Option C: It is an HIV protease inhibitor.
Option D: It is an antiretroviral protease inhibitor.
"	D
2187	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a selective inhibitor of the aromatase (oestrogen synthase) system.
Option B: It is an aromatase inhibitor.
Option C: It is a steroidal inhibitor of aromatase.
Option D: It is a nonsteroidal inhibitor of aromatase.
"	D
9829523	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an orally available small molecule inhibitor of FMS-like tyrosine kinase 3 (FLT3).
Option B: It is an inhibitor of type III tyrosine kinases, PDGFRalpha/beta and FLT3.
Option C: It inhibits insulin growth factor 1 receptor (IGF-1 receptor, IGFR1R) tyrosine kinase.
Option D: It is a dual tyrosine kinase inhibitor (TKI) of epithelial growth factor receptors (EGFR) HER2 and HER3.
"	A
89683805	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an isocitrate dehydrogenase inhibitor.
Option B: It is an orally available small molecule inhibitor of isocitrate dehydrogenase.
Option C: It is an inhibitor of carbonic anhydrase, particularly subtypes II and IV.
Option D: It is an inhibitor of isocitrate dehydrogenase 2.
"	B
3034010	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCCCC[C@@H](C[C@H]1[C@@H](C(=O)O1)CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a Neuraminidase Inhibitor.
Option B: It is a P-Glycoprotein Inhibitor.
Option C: It is a Cholinesterase Inhibitor.
Option D: It is an Intestinal Lipase Inhibitor.
"	D
42611257	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma.
Option B: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma.
Option C: It is an oral multi-kinase inhibitor used in the therapy of refractory metastatic colorectal cancer, hepatocellular carcinoma and gastrointestinal stromal tumor.
Option D: It is a selective inhibitor of BRAF kinase that is used in the therapy of patients with metastatic and advanced malignant melanoma.
"	D
489181	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3CCC(=C)CC3
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an orally available small molecule multi-kinase inhibitor that is used as an antineoplastic agent in the treatment of tenosynovial giant cell tumors.
Option B: It is a small molecule inhibitor of poly ADP-ribose polymerase used as an antineoplastic agent in the therapy of refractory and advanced ovarian carcinoma.
Option C: It is an antineoplastic agent used in the treatment of advanced, metastatic medullary thyroid cancer and refractory renal cell carcinoma.
Option D: It is a 14 alpha-demethylase inhibitor indicated in the treatment of fungal infection of the nail, known as onychomycosis.
"	D
6918456	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)OC1=CC2=C(S1)CCN(C2)C(C3=CC=CC=C3F)C(=O)C4CC4
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a P2Y12 receptor antagonist.
Option B: It is a P2Y12 Platelet Inhibitor.
Option C: It is an IP3 receptor antagonist.
Option D: It is a selective serotonin receptor antagonist.
"	B
5210	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a serotonin and norepinephrine reuptake inhibitor.
Option B: It is a selective norepinephrine reuptake inhibitor.
Option C: It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant.
Option D: It is a norepinephrine-dopamine reuptake inhibitor (NDRI).
"	A
24812758	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a sodium-glucose transport protein subtype 2 inhibitor.
Option B: It is a sodium-glucose cotransporter 2 inhibitor.
Option C: It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.
Option D: It is a sodium-dependent Pi-transporter inhibitor and a HIV-1 reverse transcriptase inhibitor.
"	C
25166913	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CC[C@H](C[C@@H]1C2=NC3=CC=CC=C3N2)NC(=O)NC4=CC=C(C=C4)C#N
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is an inhibitor of NS5A.
Option B: It is an inhibitor of the signaling molecule hedgehog.
Option C: It is an inhibitor of neuronal activity.
Option D: It is an inhibitor of cellular mitosis.
"	B
644241	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Question about this molecule: Which kind of inhibitor is this molecule?
Option A: It is a multi-specific tyrosine kinase receptor inhibitor.
Option B: It is a tyrosine kinase receptor inhibitor.
Option C: It is a specific tyrosine kinase receptor inhibitor.
Option D: It is a selective tyrosine kinase receptor inhibitor.
"	D
11317883	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1CC[C@@]2([C@@]3(C[C@]4([C@@]5([C@]([C@H]([C@@]3([C@]5([C@]2([C@@H]1O)O4)O)O)OC(=O)C6=CC=CN6)(C(C)C)O)C)O)C)O
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It is a phytogenic insecticide.
Option B: It is a non-specific insecticide.
Option C: It is used as a selective insecticide.
Option D: It is a contact and systemic insecticide.
"	A
92430	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=CC=C(C=C1)[Si](C)(C)CCCC2=CC(=C(C=C2)F)OC3=CC=CC=C3
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It is a pyrethroid ether insecticide.
Option B: It is a synthetic pyrethroid insecticide.
Option C: It is a pyrethroid ester insecticide.
Option D: It is a pyrethroid insecticide.
"	A
16752772	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C(=CC(=O)O1)N(CC2=CN=C(C=C2)Cl)CC(F)F
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It is a nicotinic acetylcholine receptor agonist insecticide.
Option B: It is a potent acetylcholinesterase-inhibiting insecticide.
Option C: It is an organophosphate acetylcholinesterase inhibitor insecticide (nematicide) used to control a wide variety of nematode (round worm) pests.
Option D: It is an organophosphate acetylcholinesterase inhibitor used as an insecticide.
"	A
16421	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOP(=S)(C1=CC=CC=C1)OC2=CC=C(C=C2)[N+](=O)[O-]
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It is an organophosphate insecticide used to control various pests.
Option B: It is an organophosphate insecticide.
Option C: It is an organothiophosphate insecticide.
Option D: It is an organophosphorus insecticide.
"	C
6758	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=C)[C@H]1CC2=C(O1)C=CC3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@H]4C3=O)OC)OC
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It has broad spectrum insecticide and pesticide activity.
Option B: It is an agricultural insecticide, particularly for rice and tea.
Option C: It is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets.
Option D: It is an effective insecticide and also repels animals like cats and dogs.
"	A
3589	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(C2C1C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl)Cl
Question about this molecule: Which kind of insecticide is this molecule?
Option A: Nearly all registered uses of it have been canceled.
Option B: It is a fast-acting insecticide with both systemic and contact action.
Option C: It is used as a non-systemic insecticide with good ovicidal properties and long persistence.
Option D: It is used as an insecticide in some horticultural applications.
"	A
13709	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=NN(C(=O)S1)CSP(=S)(OC)OC
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It is an organophosphorus insecticide.
Option B: It is an organothiophosphate insecticide.
Option C: It is an organophosphate insecticide used to control various pests.
Option D: It is an organophosphate insecticide.
"	D
6033664	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1(C(C1C(=O)OC(C#N)C2=CC(=C(C=C2)F)OC3=CC=CC=C3)/C=C(/C4=CC=C(C=C4)Cl)\\Cl)C
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It is an alpha-cyano-3-phenoxyphenyl pyrethroid insecticide used in the control of ectoparasites on cattle, sheep, goats, horses, and dogs.
Option B: It is an organophosphate, household and public health insecticide designed to control cockroaches, flies, ants, ticks, moths, fleas and mosquitoes on contact.
Option C: It is an insecticide for the control of rice leafhoppers, planthoppers, codling moth, citrus mealybug, onion thrips, fruit flies, bollworms, and aphids.
Option D: It is an organophosphate insecticide that has been used since 1959 to control insects on rice, cereals, fruits, vegetables, stored grains, cotton, to control insects in forests and for fly, mosquito, and cockroach control in public health programs.
"	A
2181	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCNC(C1)C2=CN=CC=C2
Question about this molecule: Which kind of insecticide is this molecule?
Option A: It is a piperidine botanical insecticide.
Option B: It is a non-specific insecticide.
Option C: It is a phytogenic insecticide.
Option D: It is used as a selective insecticide.
"	A
78357784	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC[C@@H](C1=CC(=C(C(=C1)OC)OC)OC)C(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)NCC(CNC(=O)COC5=CC=CC(=C5)[C@@H](CCC6=CC(=C(C=C6)OC)OC)OC(=O)[C@@H]7CCCCN7C(=O)[C@@H](CC)C8=CC(=C(C(=C8)OC)OC)OC)CN(C)C
Question about this molecule: Which kind of ligand is this molecule?
Option A: It is a minimal ligand of NOD1.
Option B: It is a bidentate ligand.
Option C: It is a cell-permeable ligand.
Option D: It is an ethylene bis(dithiocarbamate) anionic ligand.
"	C
9568620	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C(=O)NC(=O)N1/N=C/C2=NC=C(O2)C3=CC=C(C=C3)Br
Question about this molecule: Which kind of modulator is this molecule?
Option A: It is an estrogen receptor modulator.
Option B: It is a tubulin modulator.
Option C: It is a sphingosine 1-phosphate receptor modulator.
Option D: It is a ryanodine receptor modulator.
"	D
26879	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CSC2=N[C@H](CN21)C3=CC=CC=C3
Question about this molecule: How can the molecule be used as a/an modulator
Option A: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
Option B: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions.
Option C: It has immunomodulatory effects and has been studied in the treatment of various immune-mediated diseases.
Option D: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties.
"	C
3899	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
Question about this molecule: How can the molecule be used as a/an modulator
Option A: It has immunomodulatory effects and has been studied in the treatment of various immune-mediated diseases.
Option B: It is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties.
Option C: It is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.
Option D: It is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions.
"	C
10220503	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(=O)NC[C@@H]1C[C@H]1C2=C3CCOC3=CC=C2
Question about this molecule: Which kind of orphan drug is this molecule?
Option A: It is a drug for the treatment of B-CLL.
Option B: It is currently the only drug available for the treatment of N24HSWD.
Option C: It is a drug for the treatment of supranuclear palsy.
Option D: It is a drug for the treatment of CML.
"	B
135463437	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1[C@@H]2[C@@H](C([C@H]3[C@@H](O2)NC4=C(N3)C(=O)NC(=N4)N)(O)O)OP(=O)(O1)O
Question about this molecule: Which kind of orphan drug is this molecule?
Option A: It is a drug for the treatment of B-CLL.
Option B: It is a therapeutic option for patients with MoCD type A.
Option C: It is a drug for the treatment of CML.
Option D: It is a drug for the treatment of supranuclear palsy.
"	B
5993	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C2C(C(C1Cl)Cl)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl
Question about this molecule: How can the molecule be used as a/an pesticide
Option A: It was used as a pesticide on crops like corn and citrus and on home lawns and gardens until 1983.
Option B: It has been used as a pesticide in soil, and on citrus, vegetable, and grain crops.
Option C: It is used for control of mite pests on greenhouse, shadehouse, nursery, field, landscape and interiorscape grown ornamental plants.
Option D: It is used to control pest insects in soil, on ornamental plants, and on fruit and vegetable field crops.
"	A
91753	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(COC1=CC=C(C=C1)OC2=CC=CC=C2)OC3=CC=CC=N3
Question about this molecule: How can the molecule be used as a/an pesticide
Option A: It was the fourth most widely used synthetic chemical pesticide in U.S. agriculture in the 1990s.
Option B: It is a pyridine-based pesticide which is found to be effective against a variety of arthropoda.
Option C: It is used as a pesticide, particularly for killing small vertebrates such as birds and rodents.
Option D: The pesticide is also active against non-target invertebrates such as sucking insects and spider mites.
"	B
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: What is the right potential therapeutic use information about this molecule?
Option A: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Option B: It is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19.
Option C: It requires follow-up clinical trials to validate its potential therapy against SARS-CoV-2.
Option D: It is being investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease.
"	C
9829523	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Question about this molecule: What is the right potential therapeutic use information about this molecule?
Option A: It is investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Option B: It is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19.
Option C: It was initially characterized as a potential broad-spectrum antineoplastic agent, with activity toward diverse solid and hematopoietic tumors.
Option D: It is used clinically as an antihypertensive, anti-arrhythmic, and as an anti-anginal agent for the management of cardiovascular conditions such as hypertension, chronic stable angina, atrial fibrillation, atrial flutter.
"	C
135409642	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)OCC6=C(OC(=O)O6)C
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a prodrug for azilsartan, used for the treatment of hypertension.
Option B: It is a prodrug used for treatment of HIV.
Option C: It is a prodrug for aripiprazole, used for treatment of schizophrenia.
Option D: It is a prodrug used for treatment of hypertension.
"	A
71447	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)N)C(=O)OC4C5=CC=CC=C5C(=O)O4)C
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group.
Option B: It is the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug used in combination therapy for the treatment of HIV infection.
Option C: It is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin, a prodrug of ampicillin.
Option D: It is the 1-ethoxycarbonyloxyethyl ester of ampicillin, a semi-synthetic, microbiologically inactive prodrug of ampicillin.
"	C
135415867	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NOC(=O)N5)C(=O)O
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a prodrug for aripiprazole, used for treatment of schizophrenia.
Option B: It is a prodrug for azilsartan, used for the treatment of hypertension.
Option C: It is a prodrug used for treatment of HIV.
Option D: It is a prodrug used for treatment of hypertension.
"	D
2265	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.
Option B: It is a prodrug for quinaprilat hydrochloride used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure.
Option C: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Option D: It is a pro-drug of epinephrine, used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.
"	C
5394	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a prodrug for MTIC (5-(3-methyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide, formed by spontaneous hydrolysis of temozolomide in the body), used as an oral alkylating agent for the treatment of newly diagnosed malignant glioblastoma multiforme (concomitantly with radiotherapy) and malignant melanoma.
Option B: It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Option C: It is a prodrug for piroxicam, used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.
Option D: It is a prodrug for quinaprilat hydrochloride used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) for the treatment of hypertension and congestive heart failure.
"	A
3899	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a prodrug of morphine.
Option B: It is the prodrug for gabapentin.
Option C: It is a prodrug of gabapentin.
Option D: It is the prodrug of teriflunomide.
"	D
443380	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COCCOC[C@H](CC1(CCCC1)C(=O)NC2CCC(CC2)C(=O)O)C(=O)O
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a purine analogue and prodrug of mercaptopurine.
Option B: It is a 2,3-dihydro-1H-inden-5-yl ester prodrug.
Option C: It is a prodrug for 3-mercaptopyruvic acid.
Option D: It is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug.
"	B
2265	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1C=NC(=C1SC2=NC=NC3=C2NC=N3)[N+](=O)[O-]
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a prodrug of gabapentin.
Option B: It is a prodrug of morphine.
Option C: It is a prodrug of adrenaline.
Option D: It is a purine analogue and prodrug of mercaptopurine.
"	D
443380	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COCCOC[C@H](CC1(CCCC1)C(=O)NC2CCC(CC2)C(=O)O)C(=O)O
Question about this molecule: Which kind of prodrug is this molecule?
Option A: It is a purine analogue and prodrug of mercaptopurine.
Option B: It is a 2,3-dihydro-1H-inden-5-yl ester prodrug.
Option C: It is a prodrug for 3-mercaptopyruvic acid.
Option D: It is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug.
"	D
7276	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1C(O1)C2=CC=CC=C2
Question about this molecule: How can the molecule be used for production
Option A: It is used in the production of Fusilev, which has an additional indication for use in combination chemotherapy with 5-fluorouracil in the palliative treatment of patients with advanced metastatic colorectal cancer.
Option B: It is used in the production of florbetapir 18F, which is indicated for positron emission tomography (PET) imaging of the brain to estimate β-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline.
Option C: It is used in the production of tretinoin, which is used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis.
Option D: It is used as a reactive plasticizer or diluent for epoxy resins and in the production of phenethyl alcohol and styrene glycol and its derivatives.
"	D
65093	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=NC(=C1)SSC2=CC=CC=N2
Question about this molecule: Which kind of reagent is this molecule?
Option A: It is a reagent for the selective cleavage of tryptophanyl peptide bonds.
Option B: It is a reagent used in molecular biology as an oxidizing agent.
Option C: It is a reagent used particularly for the mPEGylation of free thiol groups in cysteine residues of proteins.
Option D: It is a reagent for the detection of oxidation products such as aldehydes and ketones in fats and oils.
"	B
5362449	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CC[C@]23CCCC[C@H]2[C@H]1CC4=C3C=C(C=C4)OC
Question about this molecule: How can the molecule be used for research
Option A: It has been used to research obesity and energy balance, and exerts some local analgesia effects.
Option B: It is used as one of the widely used antitussives and to study the involvement of glutamate receptors in neurotoxicity.
Option C: It is useful in research for the selection of animal cells that express the E.
Option D: It is used in contemporary research regarding novel methods to stabilize mesalazine and to decrease inflammatory activity, potentially reducing the risk of colorectal cancer in conditions like ulcerative colitis.
"	B
5546	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C2=NC3=C(N=C(N=C3N=C2N)N)N
Question about this molecule: What is the right safety concern information about this molecule?
Option A: It is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States.
Option B: It has the capability or risk for eliciting hepatotoxicity in patients.
Option C: It has been withdrawn from the market in Europe and the United States due to the risk of cardiac arrhythmias and overdose, possibly leading to death.
Option D: It has effects on increased serum potassium levels, and is associated with a risk of producing hyperkalemia.
"	D
135398736	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1[C@@H](C(=O)N1S(=O)(=O)[O-])NC(=O)/C(=N\\OC(C)(C)C(=O)O)/C2=CSC(=[NH+]2)N
Question about this molecule: What is the right safety concern information about this molecule?
Option A: It can cause spontaneous combustion when it comes in contact with organic material.
Option B: The risk appears to be highest in patients with current or past substance use disorders.
Option C: It may cause a superinfection with gram-positive organisms.
Option D: It is rarely used as an insecticide due to the risk of poisoning to humans and other animals.
"	C
68873	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CCC(=O)C=C1[C@@H]3C[C@@H]3[C@@H]4[C@@H]2CC[C@]5([C@H]4[C@@H]6C[C@@H]6[C@@]57CCC(=O)O7)C
Question about this molecule: What is the right safety concern information about this molecule?
Option A: It can cross the placental barrier during pregnancy, which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and neonatal death.
Option B: Rarely, serious complications may occur in some patients, including hemorrhagic pancreatitis, coagulopathies, bone marrow suppression, VPA-induced hepatotoxicity and encephalopathy.
Option C: The risk of venous thromboembolism with oral contraceptives such as this molecule exists but remains lower than the risk of this condition during pregnancy and during the postpartum period.
Option D: It is generally considered a lower-risk opioid option for the treatment of moderate to severe pain due to its good tolerability profile and multimodal mechanism of action.
"	C
4174	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(C1=CN=CC=C1)C(=O)C2=CN=CC=C2
Question about this molecule: What is the right testing information about this molecule?
Option A: It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Option B: Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood or bone marrow.
Option C: Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
Option D: Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test.
"	A
89683805	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O
Question about this molecule: What is the right testing information about this molecule?
Option A: Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test.
Option B: Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood or bone marrow.
Option C: Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
Option D: It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
"	B
54677470	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used in the treatment of acute pain and chronic arthritis.
Option B: It is used for the therapy of chronic arthritis.
Option C: It is used in therapy of chronic arthritis.
Option D: It can be used in the treatment of acute pain and chronic arthritis.
"	C
67505836	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CC2(CC2)C[C@H]1C3=NC=C(N3)C4=CC5=C(C=C4)C6=C(C5(F)F)C=C(C=C6)C7=CC8=C(C=C7)N=C(N8)[C@@H]9[C@H]1CC[C@H](C1)N9C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used for the treatment of chronic hepatitis C.
Option B: It is considered the first line agent for medical therapy of hyperthyroidism and Graves disease.
Option C: It is a Direct Acting Antiviral (DAA) used for the treatment of chronic Hepatitis C.
Option D: It is prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.
"	C
6292	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC=CC=C1N2C(=NC3=CC=CC=C3C2=O)C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.
Option B: It is a sedative-hypnotic drug that is similar in effect to barbiturates.
Option C: It is widely used for therapy of mild-to-moderate pain and arthritis.
Option D: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.
"	B
4614	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)O)C3=CC=CC=C3
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used for the therapy of chronic arthritis.
Option B: It is used in therapy of chronic arthritis.
Option C: It is used in the treatment of acute pain and chronic arthritis.
Option D: It can be used in the treatment of acute pain and chronic arthritis.
"	A
5833	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option B: It is used for the treatment of allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus.
Option C: It is used in the therapy of edema, particularly in patients with cirrhosis in which hyperaldosteronism appears to play a major role.
Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis.
"	C
71661251	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)[C@@H](C(=O)N1CCC[C@H]1C2=NC=C(N2)C3=CC4=C(C=C3)N5[C@@H](OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)[C@@H]8CCCN8C(=O)[C@H](C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is a Direct Acting Antiviral (DAA) used for the treatment of chronic Hepatitis C.
Option B: It is used for the treatment of chronic hepatitis C.
Option C: It is considered the first line agent for medical therapy of hyperthyroidism and Graves disease.
Option D: It is prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.
"	B
60823	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used as an antihypertensive drug.
Option B: It is used for the treatment of opioid addiction.
Option C: It is used as a lipid-lowering drug.
Option D: It is being studied as an investigational drug as part of a strategy to cure HIV infection.
"	C
41774	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used to control blood sugar levels in patients with type 2 diabetes mellitus.
Option B: It is commonly used as a first line therapy in the treatment of hypertension.
Option C: It can be used for the prevention of cardiovascular events in patients with type 2 diabetes.
Option D: It is used as an adjunctive therapy in the management of type 2 diabetes.
"	D
60846	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization.
Option B: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.
Option C: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.
Option D: It is efficacious in treating various Parkinson's symptoms such as tremor, rigidity, and bradykinesia (slow movement).
"	A
5352062	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C/C=C\\1/C(=O)N[C@H](C(=O)O[C@H]\\2CC(=O)N[C@@H](C(=O)N[C@H](CSSCC/C=C2)C(=O)N1)C(C)C)C(C)C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Option B: It is being studied as an investigational drug as part of a strategy to cure HIV infection.
Option C: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.
Option D: It is used as an adjunctive therapy for partial-onset seizures that are not adequately controlled with conventional therapy.
"	B
71301	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.
Option B: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option C: It is generally not first line therapies as many patients are first treated with thiazide diuretics.
Option D: It can be used for the therapy of leprosy and dermatitis herpetiformis.
"	C
644073	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]([C@H]1C[C@@]23CC[C@@]1([C@H]4[C@@]25CCN([C@@H]3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)(C(C)(C)C)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used for the treatment of opioid addiction.
Option B: It is used for the treatment of schizophrenia symptoms.
Option C: It is used for the treatment of hypertension.
Option D: It is used in the treatment of schizophrenia in adult patients.
"	A
441401	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It has been linked to rare instances of lactic acidosis and liver injury probably as a result of hepatic mitochondrial toxicity.
Option B: It improves cardiovascular outcomes including reducing risk of myocardial infarction, stroke, the progression of heart failure, and hospitalization.
Option C: It is used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver.
Option D: It is used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease.
"	A
969472	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN1CCN(CC1)C(=O)O[C@H]2C3=NC=CN=C3C(=O)N2C4=NC=C(C=C4)Cl
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is used in therapy of chronic arthritis.
Option B: It is used predominantly to treat chronic arthritis.
Option C: It is used for the therapy of chronic arthritis.
Option D: It is used to treat insomnia.
"	D
25137957	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCN4CCN(CC4)CCO
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used in the chronic treatment of glaucoma.
Option B: It is used in the management of chronic schizophrenic psychoses.
Option C: It is a Direct Acting Antiviral (DAA) used for the treatment of chronic Hepatitis C.
Option D: It is used for the treatment of chronic hepatitis C.
"	B
2435	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is marketed for the treatment of hypertension.
Option B: It is used for the treatment of hypertension.
Option C: It is commonly used as a first line therapy in the treatment of hypertension.
Option D: It can be used in the chronic treatment of glaucoma.
"	D
135403821	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@H]1/C=C/C=C(\\C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C=N/N5CCN(CC5)C6CCCC6)/C
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents.
Option B: It is widely used in the therapy of hypercholesterolemia, usually in combination with other agents.
Option C: It is used in combination with other agents as therapy of tuberculosis.
Option D: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.
"	D
24812758	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C=C(C=C1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is commonly used as a first line therapy in the treatment of hypertension.
Option B: It is used as an adjunctive therapy in the management of type 2 diabetes.
Option C: It can be used for the prevention of cardiovascular events in patients with type 2 diabetes.
Option D: It is used to control blood sugar levels in patients with type 2 diabetes mellitus.
"	C
16134956	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]([C@@H](C)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CC6=CN=CN6)N)C(=O)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It can be used as a useful alternative to non-selective β-blocker drugs in the treatment of hypertension.
Option B: It can be used in combination with other agents as therapy of tuberculosis, particularly in once or twice weekly regimens.
Option C: It is commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.
Option D: It can be used in the therapy of type 2 diabetes, either alone or in combination with other antidiabetic agents.
"	D
5152	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O
Question about this molecule: How can the molecule be used for therapeutic use
Option A: It is widely used for therapy of mild-to-moderate pain and arthritis.
Option B: It is used in the treatment of mild-to-moderate pain and symptoms of chronic arthritis.
Option C: It can be used for the therapy of chronic forms of arthritis and mild-to-moderate acute pain.
Option D: It is prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.
"	D
5323714	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1COC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-]
Question about this molecule: How can the molecule be used for treatment
Option A: It is used as a treatment for leishmaniasis.
Option B: It can be used in the treatment of epilepsy and bipolar disorder.
Option C: It can be used in the treatment of status epilepticus.
Option D: It is used in the treatment of giardiasis and cholera.
"	D
5281037	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCC1=NC=C(N1CC2=CC=C(C=C2)C(=O)O)/C=C(\\CC3=CC=CS3)/C(=O)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used for the treatment of severe long-term depression.
Option B: It is used for the treatment of high blood pressure.
Option C: It can be used for the treatment of major depression.
Option D: It can be used for the treatment of treatment-resistant major depression.
"	B
56927674	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C([C@H]([C@@H]1[C@H]2[C@@H](O[Sb](O2)(O1)O[Sb]34O[C@@H]([C@H](O3)[C@@H](CO)O)[C@@H](O4)C(=O)[O-])C(=O)[O-])O)O.O.O.O.O.O.O.O.O.O.O.[OH-].[Na+].[Na+].[Na+]
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the treatment of status epilepticus.
Option B: It is used as a treatment for leishmaniasis.
Option C: It is used in the treatment of giardiasis and cholera.
Option D: It can be used in the treatment of epilepsy and bipolar disorder.
"	B
4440	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CNS(=O)(=O)CCC1=CC2=C(C=C1)NC=C2C3CCN(CC3)C
Question about this molecule: How can the molecule be used for treatment
Option A: It is used for the treatment of migraine, cluster, and severe headaches within various demographics.
Option B: It is used for the treatment of migraine headaches.
Option C: It is used for treatment of gastrointestinal disorders.
Option D: It can be used for the treatment of migraine headaches.
"	B
166548	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCOC1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC=C(C=C7)O)O)O)[C@@H](C)O)C)O)O)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used as an antifungal antibiotic.
Option B: It is used as an Echinocandin Antifungal.
Option C: It is used as an antiseptic and antifungal agent.
Option D: It can be used as an antibacterial and antifungal agent.
"	B
213053	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: COC1=C(C=C(C=C1)C2=C(N=CN2C3=CC=C(C=C3)S(=O)(=O)N)Cl)F
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used for the treatment of major depression.
Option B: It can be used for the treatment of treatment-resistant major depression.
Option C: It can be used for the treatment of severe long-term depression.
Option D: It would be used to treat depression by a new mechanism of action.
"	D
3033053	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@]12CCCCC[C@H]([C@@H]1N)CC3=C2C=C(C=C3)O
Question about this molecule: How can the molecule be used for treatment
Option A: It is used for treatment of gastrointestinal disorders.
Option B: It is used for the treatment of high blood pressure.
Option C: It is used for pain management as a partial opiate drug.
Option D: It can be used for the treatment of severe long-term depression.
"	C
3823	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
Question about this molecule: How can the molecule be used for treatment
Option A: It is used in the prevention and treatment of a variety of fungal infections as an imidazole antifungal agent.
Option B: It is a prodrug for an antifungal agent used for the treatment of invasive aspergillosis and invasive mucormycosis.
Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option D: It is used to treat bacterial infections including bronchitis and urinary tract infections, and to prevent urinary tract infections prior to surgery.
"	A
5510	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2
Question about this molecule: How can the molecule be used for treatment
Option A: It is used as an antiseptic and antifungal agent.
Option B: It is used as a synthetic over-the-counter anti-fungal agent.
Option C: It can be used as an antibacterial and antifungal agent.
Option D: It can be used as an antifungal antibiotic.
"	B
108150	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=CC2=C([C@@H]3[C@@H]4[C@H]5C6=C(C(=C7C(=C6[C@@H](N4[C@H]([C@H](C2)N3C)O)COC(=O)[C@@]8(CS5)C9=CC(=C(C=C9CCN8)O)OC)OCO7)C)OC(=O)C)C(=C1OC)O
Question about this molecule: How can the molecule be used for treatment
Option A: It is used as a treatment for leishmaniasis.
Option B: It can be used for the treatment of specific soft tissue sarcomas.
Option C: It is used in the treatment of giardiasis and cholera.
Option D: It can be used in the treatment of status epilepticus.
"	B
60823	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option B: It can be used for patients following any cardiovascular event and for people at moderate to high risk of developing cardiovascular disease.
Option C: It can be used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver.
Option D: It can be used for the treatment of sickle cell disease, malaria, and some cancers.
"	B
6468	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC(CC1)(C2=CC=CC=C2)N3CCCCC3
Question about this molecule: How can the molecule be used for treatment
Option A: It is used as an antiseptic and antifungal agent.
Option B: It can be used as a hallucinogenic drug.
Option C: It can be used as an immunosuppressive and antitumor agent.
Option D: It can be used as a psychostimulant drug.
"	B
477468	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCOC1=CC=C(C=C1)C2=CC(=NO2)C3=CC=C(C=C3)C(=O)N[C@H]4C[C@H]([C@H](NC(=O)[C@@H]5[C@H]([C@H](CN5C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]6C[C@H](CN6C(=O)[C@@H](NC4=O)[C@@H](C)O)O)[C@@H]([C@H](C7=CC(=C(C=C7)O)OS(=O)(=O)O)O)O)[C@@H](CC(=O)N)O)C)O)O)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used as an antifungal antibiotic.
Option B: It is used as an Echinocandin Antifungal.
Option C: It can be used as an antibacterial and antifungal agent.
Option D: It is used as an antiseptic and antifungal agent.
"	B
71616	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H](C1=NC=NC=C1F)[C@](CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used for the treatment of sickle cell disease, malaria, and some cancers.
Option B: It can be used to treat serious fungal infections.
Option C: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option D: It can be used to treat fungal and yeast infections.
"	B
52918379	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@@H](C2=CC3=C(C=C2)OCCO3)O.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used to treat fungal and yeast infections.
Option B: It can be used to treat serious fungal infections.
Option C: It is highly effective for the management of the ""positive"" symptoms of schizophrenia.
Option D: It may provide greater benefit for some patients.
"	D
47641	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C/C=C/C1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32
Question about this molecule: How can the molecule be used for treatment
Option A: It is used as a Benzylamine Antifungal.
Option B: It is used as an Echinocandin Antifungal.
Option C: It is used as an Oxaborole Antifungal.
Option D: It can be used as an Allylamine Antifungal.
"	D
441140	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C[C@@H]1CC(=O)C=C([C@]12C(=O)C3=C(O2)C(=C(C=C3OC)OC)Cl)OC
Question about this molecule: How can the molecule be used for treatment
Option A: It is used as an antiseptic and antifungal agent.
Option B: It can be used as an antibacterial and antifungal agent.
Option C: It can be used as an antifungal antibiotic.
Option D: It is used as an Echinocandin Antifungal.
"	C
3559	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F
Question about this molecule: How can the molecule be used for treatment
Option A: It is highly effective for the management of the ""positive"" symptoms of schizophrenia.
Option B: It can be used for the treatment of treatment-resistant major depression.
Option C: It can be used in the treatment of status epilepticus.
Option D: It should not be employed for the treatment of gouty arthritis.
"	A
5078	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Question about this molecule: How can the molecule be used for treatment
Option A: It is used for treatment of gastrointestinal disorders.
Option B: It can be used for the treatment of migraine headaches.
Option C: It is used for the treatment of migraine headaches.
Option D: It is used for the treatment of migraine, cluster, and severe headaches within various demographics.
"	B
5482	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=C(C=C1Cl)Cl)C(CN2C=CN=C2)OCC3=C(SC=C3)Cl
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
Option B: It can be used to treat serious fungal infections.
Option C: It can be used for the treatment of sickle cell disease, malaria, and some cancers.
Option D: It can be used to treat fungal and yeast infections.
"	D
3878	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N
Question about this molecule: How can the molecule be used for treatment
Option A: It can be used in the treatment of epilepsy and bipolar disorder.
Option B: It can be used for the treatment of sickle cell disease, malaria, and some cancers.
Option C: It has been studied for the treatment of acute myeloid leukaemia, arthritis, and atherosclerotic plaque formation.
Option D: It can be used in the prevention of invasive fungal infections due to aspergillosis and candida in high-risk patients.
"	A
26879	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CSC2=N[C@H](CN21)C3=CC=CC=C3
Question about this molecule: What is the right withdrawal information about this molecule?
Option A: It was withdrawn in 1965 because of dissociative hallucinogenic effects that were often disturbing and sometimes severe and prolonged.
Option B: It was withdrawn within approximately 5 years of its first approval by the FDA in the 1970s due to a lack of evidence supporting its efficacy.
Option C: It was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis.
Option D: It was withdrawn from Canadian and U.S. markets in October 2010 due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
"	C
6468	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1CCC(CC1)(C2=CC=CC=C2)N3CCCCC3
Question about this molecule: What is the right withdrawal information about this molecule?
Option A: It was withdrawn from Canadian and U.S. markets in October 2010 due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Option B: It was withdrawn in 1965 because of dissociative hallucinogenic effects that were often disturbing and sometimes severe and prolonged.
Option C: It was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis.
Option D: It was withdrawn within approximately 5 years of its first approval by the FDA in the 1970s due to a lack of evidence supporting its efficacy.
"	B
5591	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC1=C(C2=C(CCC(O2)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C(=C1O)C)C
Question about this molecule: What is the right withdrawal information about this molecule?
Option A: It was withdrawn in 2000 due to the risk of hepatotoxicity.
Option B: It was withdrawn from Canadian and U.S. markets in October 2010 due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Option C: It was withdrawn within approximately 5 years of its first approval by the FDA in the 1970s due to a lack of evidence supporting its efficacy.
Option D: It was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis.
"	A
5210	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C)CC(C1(CCC1)C2=CC=C(C=C2)Cl)N(C)C
Question about this molecule: What is the right withdrawal information about this molecule?
Option A: It was withdrawn within approximately 5 years of its first approval by the FDA in the 1970s due to a lack of evidence supporting its efficacy.
Option B: It was withdrawn from Canadian and U.S. markets in October 2010 due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Option C: It was withdrawn from the American market in 2000 due to its ability to cause serious adverse effects, including agranulocytosis.
Option D: It was withdrawn in 1965 because of dissociative hallucinogenic effects that were often disturbing and sometimes severe and prolonged.
"	B
3718	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: CC(C1=CC=C(C=C1)N2CC3=CC=CC=C3C2=O)C(=O)O
Question about this molecule: What is the right withdrawn from market information about this molecule?
Option A: It was withdrawn from the market following its association with cases of Stevens-Johnson syndrome.
Option B: It was withdrawn from the market due to causing severe gastrointestinal bleeding.
Option C: It was withdrawn from the market following suspicions of carcenogenicity.
Option D: It was withdrawn from the market in 1982 due to links with hepatitis.
"	B
5280707	"Please complete the following question answering task: You are given a SMILES of a molecule and a question about it with several options, please analysis the structure of the molecule and choose the right answer for the question from given options.
Molecule SMILES: C1=COC(=C1)/C(=C/C2=CC=C(O2)[N+](=O)[O-])/C(=O)N
Question about this molecule: What is the right withdrawn from market information about this molecule?
Option A: It was withdrawn from the market in 1982 due to links with hepatitis.
Option B: It was withdrawn from the market following suspicions of carcenogenicity.
Option C: It was withdrawn from the market due to causing severe gastrointestinal bleeding.
Option D: It was withdrawn from the market following its association with cases of Stevens-Johnson syndrome.
"	B