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NCBI_disease_train

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Clinical NLP Lab 26

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: In general , a high degree of haplotype conservation across the region was observed , with haplotype differences most often due to mutations in the short - tandem - repeat markers , although some likely instances of recombination also were observed . ### Output Text:

In general , a high degree of haplotype conservation across the region was observed , with haplotype differences most often due to mutations in the short - tandem - repeat markers , although some likely instances of recombination also were observed .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: For several of the instances , there was evidence for multiple , independent , BRCA1 mutational events . ### Output Text:

For several of the instances , there was evidence for multiple , independent , BRCA1 mutational events .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Isolation of the mouse homologue of BRCA1 and genetic mapping to mouse chromosome 11 . ### Output Text:

Isolation of the mouse homologue of BRCA1 and genetic mapping to mouse chromosome 11 .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: The BRCA1 gene is in large part responsible for hereditary human breast and ovarian cancer . ### Output Text:

The BRCA1 gene is in large part responsible for <span class="disease">hereditary human breast and ovarian cancer</span> .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Here we report the isolation of the murine Brca1 homologue cDNA clones . ### Output Text:

Here we report the isolation of the murine Brca1 homologue cDNA clones .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: In addition , we identified genomic P1 clones that contain most , if not all , of the mouse Brca1 locus . ### Output Text:

In addition , we identified genomic P1 clones that contain most , if not all , of the mouse Brca1 locus .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: DNA sequence analysis revealed that the mouse and human coding regions are 75 % identical at the nucleotide level while the predicted amino acid identity is only 58 % . ### Output Text:

DNA sequence analysis revealed that the mouse and human coding regions are 75 % identical at the nucleotide level while the predicted amino acid identity is only 58 % .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: A DNA sequence variant in the Brca1 locus was identified and used to map this gene on a ( Mus m . musculus Czech II x C57BL / KsJ ) F1 x C57BL / KsJ intersubspecific backcross to distal mouse chromosome 11 . ### Output Text:

A DNA sequence variant in the Brca1 locus was identified and used to map this gene on a ( Mus m . musculus Czech II x C57BL / KsJ ) F1 x C57BL / KsJ intersubspecific backcross to distal mouse chromosome 11 .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: The mapping of this gene to a region highly syntenic with human chromosome 17 , coupled with Southern and Northern analyses , confirms that we isolated the murine Brca1 homologue rather than a related RING finger gene . ### Output Text:

The mapping of this gene to a region highly syntenic with human chromosome 17 , coupled with Southern and Northern analyses , confirms that we isolated the murine Brca1 homologue rather than a related RING finger gene .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: The isolation of the mouse Brca1 homologue will facilitate the creation of mouse models for germline BRCA1 defects . . ### Output Text:

The isolation of the mouse Brca1 homologue will facilitate the creation of mouse models for germline <span class="disease">BRCA1 defects</span> . .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Emerin deficiency at the nuclear membrane in patients with Emery - Dreifuss muscular dystrophy . ### Output Text:

<span class="disease">Emerin deficiency</span> at the nuclear membrane in patients with <span class="disease">Emery - Dreifuss muscular dystrophy</span> .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Mutations in the STA gene at the Xq28 locus have been found in patients with X - linked Emery - Dreifuss muscular dystrophy ( EDMD ) . ### Output Text:

Mutations in the STA gene at the Xq28 locus have been found in patients with <span class="disease">X - linked Emery - Dreifuss muscular dystrophy</span> ( <span class="disease">EDMD</span> ) .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: This gene encodes a hitherto unknown protein named emerin . ### Output Text:

This gene encodes a hitherto unknown protein named emerin .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: To elucidate the subcellular localization of emerin , we raised two antisera against synthetic peptide fragments predicted from emerin cDNA . ### Output Text:

To elucidate the subcellular localization of emerin , we raised two antisera against synthetic peptide fragments predicted from emerin cDNA .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Using both antisera , we found positive nuclear membrane staining in skeletal , cardiac and smooth muscles in the normal controls and in patients with neuromuscular diseases other than EDMD . ### Output Text:

Using both antisera , we found positive nuclear membrane staining in skeletal , cardiac and smooth muscles in the normal controls and in patients with <span class="disease">neuromuscular diseases</span> other than <span class="disease">EDMD</span> .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: In contrast , a deficiency in immunofluorescent staining of skeletal and cardiac muscle from EDMD patients was observed . ### Output Text:

In contrast , a deficiency in immunofluorescent staining of skeletal and cardiac muscle from <span class="disease">EDMD</span> patients was observed .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: A 34 kD protein is immunoreactive with the antisera - - the protein is equivalent to that predicted for emerin . ### Output Text:

A 34 kD protein is immunoreactive with the antisera - - the protein is equivalent to that predicted for emerin .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Together , our findings suggest the specific deficiency of emerin in the nuclear membrane of muscle cells in patients with EDMD . . ### Output Text:

Together , our findings suggest the specific <span class="disease">deficiency of emerin</span> in the nuclear membrane of muscle cells in patients with <span class="disease">EDMD</span> . .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Growth retardation and tumour inhibition by BRCA1 . ### Output Text:

<span class="disease">Growth retardation</span> and <span class="disease">tumour</span> inhibition by BRCA1 .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Inherited mutations in BRCA1 predispose to breast and ovarian cancer , but the role of BRCA1 in sporadic breast and ovarian cancer has previously been elusive . ### Output Text:

Inherited mutations in BRCA1 predispose to <span class="disease">breast and ovarian cancer</span> , but the role of BRCA1 in sporadic <span class="disease">breast and ovarian cancer</span> has previously been elusive .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Here , we show that retroviral transfer of the wild - type BRCA1 gene inhibits growth in vitro of all breast and ovarian cancer cell lines tested , but not colon or lung cancer cells or fibroblasts . ### Output Text:

Here , we show that retroviral transfer of the wild - type BRCA1 gene inhibits growth in vitro of all <span class="disease">breast and ovarian cancer</span> cell lines tested , but not <span class="disease">colon or lung cancer</span> cells or fibroblasts .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Mutant BRCA1 has no effect on growth of breast cancer cells ; ovarian cancer cell growth is not affected by BRCA1 mutations in the 5 portion of the gene , but is inhibited by 3 BRCA1 mutations . ### Output Text:

Mutant BRCA1 has no effect on growth of <span class="disease">breast cancer</span> cells ; <span class="disease">ovarian cancer</span> cell growth is not affected by BRCA1 mutations in the 5 portion of the gene , but is inhibited by 3 BRCA1 mutations .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Development of MCF - 7 tumours in nude mice is inhibited when MCF - 7 cells are transfected with wild - type , but not mutant , BRCA1 . ### Output Text:

Development of <span class="disease">MCF - 7 tumours</span> in nude mice is inhibited when MCF - 7 cells are transfected with wild - type , but not mutant , BRCA1 .

In the sentence extracted from biomedical literature, identify all the disease entities. The required answer format is the same sentence with HTML <span> tags to mark up specific entities. ### Entity Markup Guides: Use <span class="disease"> to denote a disease. ### Input Text: Most importantly , among mice with established MCF - 7 tumours , peritoneal treatment with a retroviral vector expressing wild - type BRCA1 significantly inhibits tumour growth and increased survival . . ### Output Text:

Most importantly , among mice with established <span class="disease">MCF - 7 tumours</span> , peritoneal treatment with a retroviral vector expressing wild - type BRCA1 significantly inhibits <span class="disease">tumour</span> growth and increased survival . .