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Chlorhexidine has previously demonstrated an antibacterial spectrum that includes most of the microorganisms present in the oral cavity, such as Gram-positive and Gram-negative bacteria, bacterial spores, lipophilic viruses, yeasts and dermatophytes [7].
1. Introduction
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This database has been updated with a yeast three-hybrid (Y3H) screen for MADS-domain proteins (Immink et al., 2009) using SEP3 as the third interactor.
Molecular genetic mechanisms of the
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…94 Hart et al. 2003 [17] Manual postop xray 60 70 Hart et al. 2003 [17] Manual postop xray 60 93 Matsumoto et al. 2004 [27] Manual postop xray 30 67 Tillett et al. 1988 [42] Manual (IM) postop xray 25 92 Tillett et al. 1988 [42] Manual (IM) postop xray 25 92 Tillett et al. 1988 [42] Manual (EM)…
Discussion
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A 3-day duration of UUO was used, as both AT1 and AT2 receptors are abundant in the kidney at this age and renal AT2 expression falls rapidly in the neonatal period (27, 48).
278: R640–R645, 2000.
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We reasoned that drugs that alter chromatin, such as 50Aza and TSA, might be effective at disrupting Cdkn1c expression when epigenetic marks are consolidated (Bhogal et al., 2004; Umlauf et al., 2004).
Chromatin-Modifying Drugs Transiently Disrupt
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Insulin sensitivity was measured using the insulin sensitivity index of Matsuda, a wellestablished measure of whole-body insulin sensitivity [16].
Methods
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The discovery and characterization of new tick-protective antigens is important to improve existing vaccines for the control of cattle tick infestations (de la Fuente et al. 2007a).
Results and discussion
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SM/J individuals tend to be more responsive to the effect of a high-fat diet in relation to body weight, fat depot weight, organ weight, basal glucose levels, and triglyceride levels [23,24].
Background
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spatially localized faulting that characterizes ribbon structures [Hansen and Willis, 1996, 1998, and references therein; Ghent and Hansen, 1999].
5.2. Implications for Formation of Crustal Plateau Structures
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The proportion of laboratory confirmed cases (n = 3634) among clinically diagnosed cases (10,966) is about 30% [25].
Methods
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Thirdly, ErbB-3 is characterized by a defective mechanism of clearance from the cell surface (Baulida et al., 1996; Pinkas-Kramarski et al., 1996): instead of ligand-induced internalization and degradation in lysosomes, a mechanism shared by many growth factor receptors (Sorkin and Waters, 1993), ErbB-3 is destined primarily to enter the recycling pathway (Waterman et al.
Introduction
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Then, the 29 pixels whose NDVI values were greater than 0 and less than 0.2 were seen as non-vegetation pixels (Tsai et al., 2007; Noujdina and Ustin, 2008).
5.2.2.2 Endmember Determination
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As shown recently, a different member of the Krueppel-like factor family KLF4 demonstrated a potent antiapoptotic effect upon HDACi treatment which was mediated in part by direct binding and transcriptional upregulation of p57 followed by inhibition of the stress response phosphorylation pathway [42].
Discussion
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…isoforms, despite the use of different experimental endpoints such as production of inositol phosphates (Brauner-Osborne and Krogsgaard-Larsen 1999), competitive binding (Green et al. 2000; Kaupmann et al. 1998a; Malitschek et al. 1998) or coupling to Kir3 channels (Kaupmann et al. 1998a).
1.5 The Mystery of the Sushi Repeats: GABAB(1) Receptor Isoforms
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It was found in (Hulse et al. 2007) that the effectiveness of re-sampling for imbalanced learning depends on the evaluation metrics and base learning algorithms.
1.1 Related Work
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Thus we selected BG01 and HUES-7, which were independentlyderived at BresaGen (Mitalipova et al., 2003) and Harvard University (Cowan et al., 2004) using different embryo culture, inner cell mass isolation, hESC culture and hESC passaging methods.
Introduction
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We tested different classes of corrector molecules such as corr-2b, corr-3a, corr-4a, corr-4b (Pedemonte et al., 2005), VRT-532 (Wang et al., 2006), and VRT-325 (Loo et al., 2005) for their abilities to inhibit cross-linking of L339C (TM6)/F728C (TM7).
Results
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To demonstrate the effectiveness and applicability of the proposed approach, we generated independent and anticorrelated data sets by using the same way that has been used to generate the datasets in [5].
4 Experiments
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Cross-talk between JA and SA signalling has been described in response to various attackers (Beckers and Spoel, 2006; Stout et al., 2006; Koornneef and Pieterse, 2008).
DISCUSSION
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Six cortical fields each contained a separate representation of sound fre- quency (2–32 kHz), and the range of BFs mapped in all regions covered the range of pinna-related frequency and ILD cues in the rat (Koka et al., 2008; Tollin and Koka, 2009).
Results
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SNX27 however, possesses a unique PDZ domain involved in alternative cargo trafficking (Cai et al., 2011; Gallon et al., 2014; Lauffer et al., 2010; Lunn et al., 2007; Steinberg et al., 2013; Temkin et al., 2011; Valdes et al., 2011; Wang et al., 2013), and our results now suggest an additional unique property of this protein with respect to lipid headgroup association, interacting with PtdInsP species not bound by the other family members.
DISCUSSION
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Because antibiotic inhibitory interactions can be highly specific among Streptomyces isolates (Davelos et al., 2004a; Vetsigian et al., 2011), the benefits of producing a single antibiotic may vary across communities.
Discussion
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We demonstrate that a spatial registration strategy of pooling all data disregarding disease status or scanner (study site and/or MFS) produces results with the greatest validity in terms of biological plausibility (Frisoni et al., 2010).
Influence of Image Registration Strategy
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…of a relatively larger area or volume (Alidaee et al., 2009; Beard et al., 2006; Bertuccelli et al., 2004; Gancet et al., 2005; Kovacina et al., 2002; Kuiper and Nadjm-Tehrani, 2006; Lawrence et al., 2004; Merino et al., 2006; Parunak et al., 2005; Richards et al., 2002; Sauter et al., 2005).
17.1 Introduction
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This result is consistent with the reported trend of providers ordering testing of more genes per patient.(25)
DISCUSSION
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the additional foreground 1SVMs help our algorithm remembering the detected foreground appearance, and as a result, lead to better performance than previous work using only local background models such as [18, 5].
4. Experiments
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Those with alcohol dependence ever in lifetime met at least three symptoms of maladaptive pattern of alcohol use leading to clinically significant impairment or distress (Sheehan et al., 1998; American Psychiatric Association, 2000).
Methods
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lalandi transcriptome sequences (YTK002, YTK008, YTK011, YTK017 and YTK019) [3] and three loci (Sdu21, Sdu32 and Sdu46) validated from the literature [18, 19] were used to genotype the experiment fish for parentage analysis in this study.
Methods
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Recent papers [6], [14], [15] show that spatial max and average pooling of feature maps output by intermediate convolutional layers is an effective representation, and higher performance can be achieved compared to using fully connected layers.
2. Image Retrieval with Deep Networks
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2, as well as our implementation of the algorithm introduced in [16], is freely available at http://www.
7 Numerical experiments
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…neural network connectivity between brain regions increasingly has been proposed as a key characteristic underlying memory deficits in amnestic mild cognitive impairment (aMCI), which has a high risk of conversion to Alzheimer's disease (AD) (Bai et al., 2009a, 2009b; Sorg et al., 2007).
Introduction
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It has been reported that various mechanisms such as telomere shortening, histone modification, DNA methylation and miRNA expression affect the proliferation and differentiation of MSCs, resulting in cell senescence (Bonab et al., 2006; Noer et al., 2006; Wagner et al., 2008; Zhang et al., 2008; Bork et al., 2010).
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The contamination of ground and surface water by As from soils and sediments represent significant threats to human health (WHO 2004) and, consequently, it is essential to fully understand the transport characteristics of solid phase As (Zhang and Selim 2005).
Introduction
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This co-activation of the tongue protrudor and retractor muscles is particularly significant, as this has only been reported in the isolated rodent UAW [3].
Discussion
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We trained the ve di erent merged architectures described in gure 2c-2g ve times for ResNet-164 and for DenseNet100-BC.
4 EXPERIMENTS
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We need to look at the sign of a few derivatives to identify the impact of an increase in risk, which implies some calculations (Nishimura and Ozaki, 2007): sign of 2
3. A REAL OPTION TO INVEST UNDER CHOQUET-BROWNIAN AMBIGUITY
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Mutations in ATRX result in loss of ATRX protein by immunostaining and are thought to mediate loss of function (1).
INTRODUCTION
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Pupillometry has been proposed as a simple and sensitive tool to detect subclinical autonomic dysfunction [30,31].
Methods
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…back-propagation learning, Mixture-ofExperts (ME) model (Jacobs et al., 1991; Jordan & Jacobs, 1994; Jordan & Xu, 1995) and its alternative model (Xu, 1998a; Xu et al., 1995), as well as normalized RBF nets (Moody & Darken, 1989; Nowlan, 1990; Xu et al., 1994) and its extensions (Xu, 1998a), but…
1. Introduction
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Furthermore TGFβ is the only inhibitor of myogenesis that does not stimulate myoblast proliferation (Florini et al., 1986; Massague et al., 1986; Olson et al., 1986).
DISCUSSION
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The Illumina platform and Roche GS-FLX are an effective combination to call SNPs when lacking a reference genome [17–20], but additional labor, time and cost are required to build a rough reference with GS-FLX.
Introduction
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The risk of death of PWA, as compared to non-PWA, was estimated using sex-and agestandardized mortality ratios (SMRs).17 SMRs were calculated as the ratio between the observed number of deceased PWA who had a specific can er to the expected one, estimated on the basis of sex- and age-specific (quinquennia) mortality rates among non-PWA, multiplied by the person-years at risk among PWA.
Methods
0method
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true
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0
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Ecological parameters of WNV transmission have yet to be clearly defined in tropical ecosystems typical of the Caribbean Basin countries.(1) Serosurveys of free-ranging birds in several countries have identified infections in numerous species of
INTRODUCTION
1background
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1
false
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140
137
4explicit
1
0
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This approach is a modified version of the dynamic bioclimate envelope model developed by Cheung et al. (2008a).
Sample of marine fish and invertebrates
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4explicit
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Cysteine to serine mutation of WhiB1 was generated by overlapping extension PCR using a primer pair consisting of wild type [23] and appropriately mutated primer as mentioned in the Table 2 (Additional file 2).
Bacterial strains and reagents
0method
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0
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A type I T-cell gene signature that promotes both the generation and tumor infiltration of cytotoxic T cells has been shown to be associated with an improved clinical outcome in a variety of tumor types (2, 3).
1background
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4explicit
1
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The literature describes substantial variation in dentists’ assessments of clinical, community, and behavioral factors that influence their decisions to provide a particular restorative treatment for their patients (21-23).
Discussion
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In studies that report intakes as frequency, we converted a serving size as 80 g according to other meta-analysis [15, 16].
Methods
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4explicit
0
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In addition, PTH-induced release of calcium from bone is substantially impaired in the presence of hypomagnesaemia, as magnesium depletion interferes with the generation of cAMP in response to PTH [2, 3].
Discussion
1background
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1
false
3none
203
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4explicit
1
0
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We also used an example based MT (EBMT) system [31] [32] which was developed by Joshi et al.
3. Experimental Setup
0method
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47
4explicit
0
0
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Ultimately, telomerase-deficient cells undergo replicative senescence, a process in which the majority of cells in the culture cease to grow, and a variety of deleterious genome-destabilizing events increase in frequency (Chen and Kolodner, 1999; Hackett et al., 2001; DuBois et al., 2002; Hackett and Greider, 2003; Mieczkowski et al., 2003; Meyer and Bailis, 2007).
Introduction
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As in previous studies, injury severity was stratified using the discharge diagnosis ICD-9ebased ICISS scoring system, which has been shown to outperform other scoring systems in predicting injury mortality and is particularly suited for the study of administrative databases.(8,9,12,13) The definition of severely injured patients was chosen to match that in several preceding studies that focused on the survival advantage of severely injured patients treated at DTCs in Florida.
DISCUSSION
2result
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0
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4explicit
0
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Animal treatment Regeneration of soleus muscles in 300–330 g male Wistar rats was induced by notexin as described previously (Zádor et al. 1996).
Methods
0method
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5
true
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4explicit
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The fusion reaction is probably triggered by the low pH in the lysosomes (Helenius et al., 1980a, b; White & Helenius, 1980; White et al., 1980).
INTRODUCTION
1background
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4explicit
1
0
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These coordinates correspond to the functional center of the hindpaw cortical map in C and HU14 groups as determined in a prior study [18].
Methods
0method
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0
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4explicit
0
0
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As the study arms might not be comparable at baseline, even in RCTs, we used Becker’s strategy to adjust for the reported difference between arms at baseline when calculating SMDs; for pre-and-post intervention studies without a comparison arm and for serial cross-sectional intervention studies, we assumed the value for the comparison arm was zero [51].
Methods
0method
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4
true
3none
66
63
2acronym
0
0
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According to the model results presented here, this would cause cool waters off Oman, consistent with the G. bulloides record.
4.1. Model Results in a Paleocontext
2result
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0properNoun
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Previous studies established that caveolin-3 is recovered from neonatal rat cardiomyocyte cultures in light vesicular membranes, along with flotillin-1 and flotillin-2/ESA (19).
RESULTS
2result
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5
true
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4explicit
0.601
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Based on our current results and a previous study involving development of motor innervation in the small intestine (Ward et al. 2006), ICC-DMP may mediate a significant portion of cholinergic responses in the circular muscle layer.
Discussion
2result
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0
true
3none
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2acronym
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0
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75 to 1 mg/kg per day for 3 months, then 40 mg/d for 3 months, and finally tapering to 20 mg/d or 20 mg every other day for 6 months, for a total treatment time of approximately 1 year.(1,3,5,17,66,68,71,72,74) Monitoring for untoward effects of steroid therapy such as gastrointestinal bleeding, hyperglycemia, fluid retention, depression, personality changes, psychosis, and restlessness is a priority of care.
1background
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2
true
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4explicit
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a) Comparison with known results: The model considered by Neely [22] is the same as R-model-U.
D. Discussion
2result
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(33) showed that VT measured with whole body plethysmography was similar to that measured with pneumotachography under normal conditions in urethane-anesthetized mice, which suggests that the decompression component is small under such conditions.
METHODS
0method
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0
false
3none
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4explicit
0
0
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PTOV1 can bind to flotillin-1 (Santamaria et al. 2005) and the 14-3-3 protein (Benzinger et al. 2005), which can interact with CDK1 (Chan et al. 1999).
Discussion
1background
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4explicit
0.7645
0
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The mitochondrial permeability transition pore (mPTP) is emerging as a critical player in neurodegenerative disease and in acute neuropathology (Martin et al., 2009; Martin, 2010a,b).
INTRODUCTION
1background
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0
false
3none
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4explicit
1
0
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In addition, tSC processes extending from denervated endplates contact intact nerve terminals and form “tSC bridges” that induce and guide terminal sprouts to denervated endplates (Son and Thompson, 1995a; Love et al., 2003).
M2/4
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1
false
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4explicit
1
0
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Food and water was available ad lib. Apparatus The apparatus used to test subjects had been described in detail elsewhere (Parr et al. 2006, 2008).
Method
0method
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0
true
3none
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4explicit
0
0
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The substrate recognition sequence is highly conserved in all flaviviruses and consists of two basic residues in P2 and P1 followed by a small unbranched amino acid in P1’ [22,43].
Introduction
1background
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2
false
3none
179
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4explicit
1
0
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These variables are commonly used in the literature when comparing and describing nursing homes (Castle, 2001; Castle & Engberg, 2008; Department of Health and Human Services, 2009).
METHOD
0method
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0
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4explicit
0
0
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The change in the apparent diameter of the particles was calculated using equation (1), where di is the diameter of the protein-coated particles and ds is the apparent diameter of the sample after immunogold-labelling:
Methods
0method
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0
false
3none
86
83
4explicit
0
0
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As reported by others (Roshan et al. 2003; Fisher et al. 2002), the results of SICI with threshold tracking showed two periods of maximal inhibition at ISIs 1 and 3 ms.
Discussion
2result
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2
true
0supportive
62
22
4explicit
0.7509
0.7509
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The finding that the less effective strategy and fewer relevant results saved lead to lower satisfaction is supported by previous research (Bilal & Kirby, 2002; Wang et al., 2000).
Discussion
2result
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1
false
3none
159
140
4explicit
0
0
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To achieve this aim, we used the Traditional Beliefs About Gender and Identity scale (TBGI; Dasgupta & Rivera, 2006).
Overview of the Studies and Hypotheses
0method
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4explicit
1
0
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Several previous studies showed that both EAV and PRRSV infections induce apoptosis via TNF receptor signaling (68, 111).
3.4 Discussion
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4explicit
0
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According to a recent meta-analysis of the psychological interventions in FM [24], only five randomised, controlled trials have assessed PC as one of the outcomes [25-29].
Introduction
0method
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4explicit
0
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To alleviate the bias toward some area of the space in which the population is initialized, we used a non-uniformly (asymmetrically) initialization range [3], as given in Table 1, that does not
4.2. Experimental settings
0method
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1
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4explicit
0.7595
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2002), nucleic acids (McCallum and Pardi 2003) and protein– RNA complexes (Bayer et al. 1999).
Introduction
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1
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4explicit
1
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It has been repeatedly shown that plasmodesmata, which form a system of intercellular communication, play an important role in differentiation of multicellular plant organisms [10].
Introduction
1background
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4explicit
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Aggregates or similar special predicates have been already built in several ASP solvers [4, 26]: the next example shows how to fast prototype aggregate semantics without taking into account of the efficiency of a built-in implementation.
1 Introduction
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4explicit
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The distribution of Lagrangian coherent structures (LCS)—the flow boundaries in unsteady flows—can be further extracted as the ridges in stochastic FTLE fields [2].
1 INTRODUCTION
1background
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4explicit
1
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The stimuli consisted of individual sentences, ten words in length, many of which were used in Leonard and Baum (1998).
Stimuli
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4explicit
0.6092
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Recently, a few real option models characterized by the presence of Knightian uncertainty( or ambiguity) 8 have been proposed (Nishimura and Ozaki, 2007; Asano, 2005; Trojanowska and Kort, 2010; Miao and Wang, 2010).
1background
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5
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4explicit
1
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The adaptive designs in Bartroff and Lai (2008) and this article can fulfill the seemingly disparate requirements of flexibility and efficiency on a design.
1. INTRODUCTION
1background
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9
false
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47
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4explicit
1
0
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They comprised 136 strains isolated from clinical environments; 42 strains isolated from intertidal sand contaminated by Prestige’s crude oil [23]; 50 strains from our laboratory collection, which have been previously studied by multilocus sequence analysis, MLSA [6, 20, 22]; and strain PE, which was isolated from a bioreactor seeded with the commercial compound Putidoil®.
Methods
0method
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1
false
3none
275
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4explicit
1
0
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Consequently, AMPKα phosphorylation is higher in the liver of Tg mice, resulting in increased phosphorylation and inhibition of ACC [72].
Discussion
1background
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4
true
3none
136
132
4explicit
0.733
0
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Since androgen stimulation could induce DNA damage in androgen-deprived prostate cancer cells (Figure 1 and 2) (4), we aimed to determine if exposure of AR-positive cells to supraphysiological levels of androgens for 6 hours (the point of maximal induction of DSBs, but absence of significant androgen mediated cell cycle progression as shown in Figure 1 and 2) could synergize with IR.
RESULTS
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Image Webs The most related algorithm to our proposed incremental construction method is Image Webs [3].
3.2 Discussion
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Aniline exposure increases the expression of CDKs CDKs are core components of the cell cycle machinery and the vital regulators driving cell cycle progression (Malumbres and Barbacid, 2001; Olashaw and Pledger, 2002; Chulu and Liu, 2009; Malumbres and Barbacid, 2009).
Results
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Other studies demonstrated that Period 1 (per1), another member of the Period family, and per2 exhibit circadian oscillations in mRNA expression in human peripheral leucocytes [5-8].
Introduction
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Also, recent studies from our laboratory indicated that the human intestinal Caco2 cell line is a suitable model for the human intestinal epithelia to investigate the regulation of the Cl−/OH− exchange process [23, 24].
Introduction
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Because ribbons and short-wavelength folds occur together at the margins of crustal plateaus and show compatible principal strain orientations [Ghent and Hansen, 1999], it is possible that they formed simultaneously, under the principle that the shortest-wavelength tectonic features represent the…
2.2. Implications of a Shallow BDT
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Despite no significant changes in active GLP-1 levels, 2.3- and 2.2-fold higher insulin (P = 0.045) and IGF-1 levels (P = 0.0045) were found in R6/2 mouse cortex compared to WT littermates (Fig.
Results
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Our earlier work has stressed the importance of electric field frequency and phase with respect to intracellular chemical oscillators (Kindzelskii and Petty, 2000).
Discussion
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Such a process favors local systems to take over on long-distance brain connections and decreases intellectual abilities, (van den Heuvel et al., 2009) which lead to a hypothesis of a continuum in the intrinsic network degradation from normal aging to mild cognitive impairment to AD dementia.
1. Introduction
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In addition, both sustained and selective attention were measured with the Continuous Performance Task (CPT) [21].
2. Method
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The complexity of the tumor is increased by its extreme heterogeneity, supported by a vast array of genetic changes and cross-talk between signaling pathways (36, 37), which supply and sustain its high proliferation rate and its ability to infiltrate the surrounding normal parenchyma, representing themajor driving force behind tumor recurrence.
Discussion
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We found a negative correlation of hyperactivity and BOLD response in the striatal node 1, which is consistent with previous studies in both clinical (2, 20) and nonclinical samples (35).
Discussion
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A surface-exposed pocket of SspA that includes the Tyr92 residue is important for SspA activity [42] (Figure 5A), raising the question of whether phosphorylation of Tyr92 affects SspA activity.
Results
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We have investigated breast cancer cell invasion in response to signaling cues and stromal cells, such as cancer-associated fibroblasts and ECs [28, 32].
INTRODUCTION
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Both phylogenies show bindin alleles of each Neotropical species of Echinometra clustered into reciprocally monophyletic units, but in the McCartney and Lessios (2004) phylogeny, the sister clade of E. lucunter alleles consisted of alleles of E. vanbrunti.
Results
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In school-age children with CP, other researchers have found behavioral problems including passivity, immaturity, and anxiety (Graham & Rutter, 1968b; Haslett, 1978; Hourcade & Parette, 1984; Rosenbloom, 1971).
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