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[INST] Create new Small molecule for target with these components: {'P53539': 'MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSYTSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL', 'P17535': 'METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAAALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTSSQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPGELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALKDEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY'}; your molecule must be in SMILES format. [/INST]COc1cccc2c1NC(C(=O)O)C1CC=CC21,CCOC(=O)C1Nc2c(OC)cccc2C2C=CCC12,CNC(=O)C1Nc2c(OC)cccc2C2C=CCC12,COc1cccc2c1NC(C(=O)Nc1ccccc1)C1CC=CC21,COc1cccc2c1NC(CO)C1CC=CC21,COc1cccc2c1N(C(C)=O)C(C(=O)O)C1CC=CC21,COc1cccc2c1NC(C(=O)O)C1CCCC21,Cc1cccc2c1NC(C(=O)O)C1CC=CC21,CCOC(=O)c1nc2c(C)cccc2c2c1CCC2,Cc1cccc2c3c(c(C(=O)O)nc12)CCC3,COc1cc(OC)c2c(C(=O)O)nc3c(OC)cccc3c2c1,COc1cc(OC)c2c(C3CCN(C(=O)OC(C)(C)C)CC3)nc3c(OC)cccc3c2c1,COc1cc(OC)c2c(C3CCNCC3)nc3c(OC)cccc3c2c1,COc1cc(OC)c2c(C3CCN(C(C)=O)CC3)nc3c(OC)cccc3c2c1,CCc1nc2c(OC)cccc2c2cc(OC)cc(OC)c12 |
[INST] Create new Unknown for target with these components: {'Q9EP73': 'MRIFAGIIFTACCHLLRAFTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQITDVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYPEAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQNHTAELIIPELPATHPPQNRTHWVLLGSILLFLIVVSTVLLFLRKQVRMLDVEKCGVEDTSSKNRNDTQFEET', 'Q02242': 'MWVRQVPWSFTWAVLQLSWQSGWLLEVPNGPWRSLTFYPAWLTVSEGANATFTCSLSNWSEDLMLNWNRLSPSNQTEKQAAFCNGLSQPVQDARFQIIQLPNRHDFHMNILDTRRNDSGIYLCGAISLHPKAKIEESPGAELVVTERILETSTRYPSPSPKPEGRFQGMVIGIMSALVGIPVLLLLAWALAVFCSTSMSEARGAGSKDDTLKEEPSAAPVPSVAYEELDFQGREKTPELPTACVHTEYATIVFTEGLGASAMGRRGSADGLQGPRPPRHEDGHCSWPL'}; your molecule must be in SMILES format. [/INST]Cc1c(COc2cc(OCc3cccc(C#N)c3)c(CNC(C)(C)C(=O)O)cc2Cl)cccc1-c1ccccc1 |
[INST] Create new Unknown for target with these components: {'Q9EP73': 'MRIFAGIIFTACCHLLRAFTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRGRASLPKDQLLKGNAALQITDVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATSEHELICQAEGYPEAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRSQPGQNHTAELIIPELPATHPPQNRTHWVLLGSILLFLIVVSTVLLFLRKQVRMLDVEKCGVEDTSSKNRNDTQFEET', 'Q02242': 'MWVRQVPWSFTWAVLQLSWQSGWLLEVPNGPWRSLTFYPAWLTVSEGANATFTCSLSNWSEDLMLNWNRLSPSNQTEKQAAFCNGLSQPVQDARFQIIQLPNRHDFHMNILDTRRNDSGIYLCGAISLHPKAKIEESPGAELVVTERILETSTRYPSPSPKPEGRFQGMVIGIMSALVGIPVLLLLAWALAVFCSTSMSEARGAGSKDDTLKEEPSAAPVPSVAYEELDFQGREKTPELPTACVHTEYATIVFTEGLGASAMGRRGSADGLQGPRPPRHEDGHCSWPL'}; your molecule must be in SMILES format. [/INST]Cc1c(COc2cc(OCc3cccc(C#N)c3)c(CNC(C)(C)C(=O)O)cc2Cl)cccc1-c1ccccc1,CC(=O)N[C@H]1CSSC[C@@H](C(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O,CC(=O)N[C@H]1CSSC[C@@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(N)=O)[C@@H](C)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O,CC(C)C[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)O)[C@@H](C)O |
[INST] Create new Small molecule for target with these components: {'P28223': 'MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV', 'Q14416': 'MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL'}; your molecule must be in SMILES format. [/INST]COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1 |
[INST] Create new Small molecule for target with these components: {'P28223': 'MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV', 'Q14416': 'MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL'}; your molecule must be in SMILES format. [/INST]COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COc1c(O)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COCCOc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COCCOc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COCCOc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COCCOc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,Oc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COc1c(OCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COCCOc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COc1c(OCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COCCOc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COCCOc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COCCOc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COCCOc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,Oc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COc1c(OCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COCCOc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COc1c(OCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COCCOc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COCCOc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COCCOc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COCCOc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,Oc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COc1c(OCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COCCOc1cccc(C(=O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC,COc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COCCOc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1,COCCOc1cccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c1,COCCOc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,Oc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)cc1,COc1c(OCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1,COc1c(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc2ccc(C3CCN(c4ccn5c(CC6CC6)nnc5c4Cl)CC3)cc2)cccc1C(=O)C1CCN(CCc2ccc(F)cc2)CC1 |
[INST] Create new Unknown for target with these components: {'P35968': 'MQSKVLLAVALWLCVETRAASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGERVISFHVTRGPEITLQPDMQPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEIIILVGTAVIAMFFWLLLVIILRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDYVGAIPVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDSGMVLASEELKTLEDRTKLSPSFGGMVPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSEEAELLKLIEIGVQTGSTAQILQPDSGTTLSSPPV', 'P41212': 'MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVPVPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFMKTPDEIMSGRTDRLEHLESQELDEQIYQEDEC'}; your molecule must be in SMILES format. [/INST]COc1ccc(-c2cnn3c(N)c(-c4ccccc4)c(OC4CCN(C)CC4)nc23)cc1OC,COc1ccc(-c2cnn3c(N)c(-c4ccccc4)c(OC4CCNCC4)nc23)cc1OC,COc1ccc(-c2cnn3c(N)c(-c4ccccc4)c(OCCCN(C)C)nc23)cc1OC,COc1ccc(-c2cnn3c(N)c(-c4ccccc4)c(NC4CCN(C)CC4)nc23)cc1OC,COc1ccc(-c2cnn3c(N)c(-c4ccccc4)c(NCCCN(C)C)nc23)cc1OC,COc1ccc(-c2cnn3c(N)c(-c4ccccc4)c(NC4CC(C)(C)N(C)C(C)(C)C4)nc23)cc1OC,CN1C(C)(C)CC(Nc2nc3c(-c4ccc(C(=O)N5C[C@@H]6C[C@H]5CO6)cc4)cnn3c(N)c2-c2ccccc2)CC1(C)C,COC(=O)N1CCN(C(=O)c2ccc(-c3cnn4c(N)c(-c5ccccc5)c(NC5CC(C)(C)N(C)C(C)(C)C5)nc34)cc2)CC1,CN1C(C)(C)CC(Nc2nc3c(-c4ccc(C(=O)N5CCN(S(C)(=O)=O)CC5)cc4)cnn3c(N)c2-c2ccccc2)CC1(C)C |
[INST] Create new Small molecule for target with these components: {'P35498': 'MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCIQWPPTNASLEEHSIEKNITVNYNGTLINETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMIEQLKKQQEAAQQAATATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFQKSESEDSIRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCQLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGVAYVKRKIYEFIQQSFIRKQKILDEIKPLDDLNNKKDSCMSNHTAEIGKDLDYLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPVEEQPVVEPEETLEPEACFTEGCVQRFKCCQINVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTGDRFDIEDVNNHTDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSEYVTTILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKIKGGANLLIKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F |
[INST] Create new Small molecule for target with these components: {'P35498': 'MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCIQWPPTNASLEEHSIEKNITVNYNGTLINETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMIEQLKKQQEAAQQAATATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFQKSESEDSIRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCQLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGVAYVKRKIYEFIQQSFIRKQKILDEIKPLDDLNNKKDSCMSNHTAEIGKDLDYLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPVEEQPVVEPEETLEPEACFTEGCVQRFKCCQINVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTGDRFDIEDVNNHTDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSEYVTTILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKIKGGANLLIKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C,C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)CC1 |
[INST] Create new Small molecule for target with these components: {'P35498': 'MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCIQWPPTNASLEEHSIEKNITVNYNGTLINETVFEFDWKSYIQDSRYHYFLEGFLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMIEQLKKQQEAAQQAATATASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDEDEFQKSESEDSIRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTDHFNNVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIASDCQLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGVAYVKRKIYEFIQQSFIRKQKILDEIKPLDDLNNKKDSCMSNHTAEIGKDLDYLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPVEEQPVVEPEETLEPEACFTEGCVQRFKCCQINVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTGDRFDIEDVNNHTDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSEYVTTILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKIKGGANLLIKEDMIIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C,C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)CC1,CS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(C3CC3)c(Cl)c2)cc1F,Cc1cn(-c2ccccc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccccc2F)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(F)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(Cl)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(Cl)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,COc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,Cc1cn(-c2cccc(C(F)(F)F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cncc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(Cl)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2ccc(C(F)(F)F)nc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc12 |
[INST] Create new Small molecule for target with these components: {'A2APX8': 'MEQTVLVPPGPDSFNFFTRESLAAIERRIAEEKAKNPKPDKKDDDENGPKPNSDLEAGKNLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAIFRFSATSALYILTPFNPLRKIAIKILVHSLFSMLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKIIARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVDLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCVQWPPTNASLEEHSIEKNITMDYNGTLVNETVFEFDWKSYIQDSRYHYFLEGVLDALLCGNSSDAGQCPEGYMCVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEAAQQAAATTASEHSREPSAAGRLSDSSSEASKLSSKSAKERRNRRKKRKQKEQSGGEEKDDDEFHKSESEDSIRRKGFRFSIEGNRLTYEKRYSSPHQSLLSIRGSLFSPRRNSRTSLFSFRGRAKDVGSENDFADDEHSTFEDNESRRDSLFVPRRHGERRNSNLSQTSRSSRMLAVFPANGKMHSTVDCNGVVSLVGGPSVPTSPVGQLLPEVIIDKPATDDNGTTTETEMRKRRSSSFHVSMDFLEDPSQRQRAMSIASILTNTVEELEESRQKCPPCWYKFSNIFLIWDCSPYWLKVKHIVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEHFNHVLTVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVTLSLVELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKIATDCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLTVFMMVMVIGNLVVLNLFLALLLSSFSADNLAATDDDNEMNNLQIAVDRMHKGIAYVKRKIYEFIQQSFVKKQKILDEIKPLDDLNNRKDNCISNHTTEIGKDLDCLKDVNGTTSGIGTGSSVEKYIIDESDYMSFINNPSLTVTVPIAVGESDFENLNTEDFSSESDLEESKEKLNESSSSSEGSTVDIGAPAEEQPVIEPEETLEPEACFTEGCVQRFKCCQISVEEGRGKQWWNLRRTCFRIVEHNWFETFIVFMILLSSGALAFEDIYIDQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGYQTYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCVNTTTGDIFEISEVNNHSDCLKLIERNETARWKNVKVNFDNVGFGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEESLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGMVFDFVTRQVFDISIMILICLNMVTMMVETDDQSDYVTSILSRINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPNKVNPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFMEFEKLSQFAAALEPPLNLPQPNKLQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYQPITTTLKRKQEEVSAVIIQRAYRRHLLKRTVKQASFTYNKNKLKGGANLLVKEDMLIDRINENSITEKTDLTMSTAACPPSYDRVTKPIVEKHEQEGKDEKAKGK', 'P97952': 'MGTLLALVVGAALVSSAWGGCVEVDSDTEAVYGMTFKILCISCKRRSETTAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFDNYEHNTSVVKKIHLEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMVYCYKKIAAATEAAAQENASEYLAITSESKENCTGVQVAE', 'Q56A07': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTAPTTLSVLNGSDTRLPCTFNSCYTVNHKQFSLNWTYQECNNCTEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLEDEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKMDGEGNAEDGTK'}; your molecule must be in SMILES format. [/INST]Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl |
[INST] Create new Small molecule for target with these components: {'P35499': 'MARPSLCTLVPLGPECLRPFTRESLAAIEQRAVEEEARLQRNKQMEIEEPERKPRSDLEAGKNLPMIYGDPPPEVIGIPLEDLDPYYSNKKTFIVLNKGKAIFRFSATPALYLLSPFSVVRRGAIKVLIHALFSMFIMITILTNCVFMTMSDPPPWSKNVEYTFTGIYTFESLIKILARGFCVDDFTFLRDPWNWLDFSVIMMAYLTEFVDLGNISALRTFRVLRALKTITVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALVGLQLFMGNLRQKCVRWPPPFNDTNTTWYSNDTWYGNDTWYGNEMWYGNDSWYANDTWNSHASWATNDTFDWDAYISDEGNFYFLEGSNDALLCGNSSDAGHCPEGYECIKTGRNPNYGYTSYDTFSWAFLALFRLMTQDYWENLFQLTLRAAGKTYMIFFVVIIFLGSFYLINLILAVVAMAYAEQNEATLAEDKEKEEEFQQMLEKFKKHQEELEKAKAAQALEGGEADGDPAHGKDCNGSLDTSQGEKGAPRQSSSGDSGISDAMEELEEAHQKCPPWWYKCAHKVLIWNCCAPWLKFKNIIHLIVMDPFVDLGITICIVLNTLFMAMEHYPMTEHFDNVLTVGNLVFTGIFTAEMVLKLIAMDPYEYFQQGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKIALDCNLPRWHMHDFFHSFLIVFRILCGEWIETMWDCMEVAGQAMCLTVFLMVMVIGNLVVLNLFLALLLSSFSADSLAASDEDGEMNNLQIAIGRIKLGIGFAKAFLLGLLHGKILSPKDIMLSLGEADGAGEAGEAGETAPEDEKKEPPEEDLKKDNHILNHMGLADGPPSSLELDHLNFINNPYLTIQVPIASEESDLEMPTEEETDTFSEPEDSKKPPQPLYDGNSSVCSTADYKPPEEDPEEQAEENPEGEQPEECFTEACVQRWPCLYVDISQGRGKKWWTLRRACFKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRRVIRTILEYADKVFTYIFIMEMLLKWVAYGFKVYFTNAWCWLDFLIVDVSIISLVANWLGYSELGPIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYYCINTTTSERFDISEVNNKSECESLMHTGQVRWLNVKVNYDNVGLGYLSLLQVATFKGWMDIMYAAVDSREKEEQPQYEVNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGKDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPQNKIQGMVYDLVTKQAFDITIMILICLNMVTMMVETDNQSQLKVDILYNINMIFIIIFTGECVLKMLALRQYYFTVGWNIFDFVVVILSIVGLALSDLIQKYFVSPTLFRVIRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMSNFAYVKKESGIDDMFNFETFGNSIICLFEITTSAGWDGLLNPILNSGPPDCDPNLENPGTSVKGDCGNPSIGICFFCSYIIISFLIVVNMYIAIILENFNVATEESSEPLGEDDFEMFYETWEKFDPDATQFIAYSRLSDFVDTLQEPLRIAKPNKIKLITLDLPMVPGDKIHCLDILFALTKEVLGDSGEMDALKQTMEEKFMAANPSKVSYEPITTTLKRKHEEVCAIKIQRAYRRHLLQRSMKQASYMYRHSHDGSGDDAPEKEGLLANTMSKMYGHENGNSSSPSPEEKGEAGDAGPTMGLMPISPSDTAWPPAPPPGQTVRPGVKESLV', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl |
[INST] Create new Small molecule for target with these components: {'Q14524': 'MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVNSHERRSKRRKRMSSGTEECGEDRLPKSDSEDGPRAMNHLSLTRGLSRTSMKPRSSRGSIFTFRRRDLGSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQPSPGTSAPGHALHGKKNSTVDCNGVVSLLGAGDPEATSPGSHLLRPVMLEHPPDTTTPSEEPGGPQMLTSQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRHKCPPCWNRLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETRFEEGEQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEENSLGTEEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSAMVIQRAFRRHLLQRSLKHASFLFRQQAGSGLSEEDAPEREGLIAYVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F |
[INST] Create new Small molecule for target with these components: {'Q14524': 'MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVNSHERRSKRRKRMSSGTEECGEDRLPKSDSEDGPRAMNHLSLTRGLSRTSMKPRSSRGSIFTFRRRDLGSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQPSPGTSAPGHALHGKKNSTVDCNGVVSLLGAGDPEATSPGSHLLRPVMLEHPPDTTTPSEEPGGPQMLTSQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRHKCPPCWNRLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETRFEEGEQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEENSLGTEEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSAMVIQRAFRRHLLQRSLKHASFLFRQQAGSGLSEEDAPEREGLIAYVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C,C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)CC1 |
[INST] Create new Small molecule for target with these components: {'Q14524': 'MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSTTLQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPQELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPIRRAAVKILVHSLFNMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIIMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVNSHERRSKRRKRMSSGTEECGEDRLPKSDSEDGPRAMNHLSLTRGLSRTSMKPRSSRGSIFTFRRRDLGSEADFADDENSTAGESESHHTSLLVPWPLRRTSAQGQPSPGTSAPGHALHGKKNSTVDCNGVVSLLGAGDPEATSPGSHLLRPVMLEHPPDTTTPSEEPGGPQMLTSQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRHKCPPCWNRLAQRYLIWECCPLWMSIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDREMNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSCIATPYSPPPPETEKVPPTRKETRFEEGEQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEENSLGTEEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADWRQQWKAEPQAPGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQAPGKVWWRLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSQCESLNLTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSAMVIQRAFRRHLLQRSLKHASFLFRQQAGSGLSEEDAPEREGLIAYVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C,C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)CC1,CS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(C3CC3)c(Cl)c2)cc1F,Cc1cn(-c2ccccc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccccc2F)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(F)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(Cl)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(Cl)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,COc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,Cc1cn(-c2cccc(C(F)(F)F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cncc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(Cl)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2ccc(C(F)(F)F)nc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc12 |
[INST] Create new Small molecule for target with these components: {'P97952': 'MGTLLALVVGAALVSSAWGGCVEVDSDTEAVYGMTFKILCISCKRRSETTAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFDNYEHNTSVVKKIHLEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMVYCYKKIAAATEAAAQENASEYLAITSESKENCTGVQVAE', 'Q56A07': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTAPTTLSVLNGSDTRLPCTFNSCYTVNHKQFSLNWTYQECNNCTEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLEDEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKMDGEGNAEDGTK', 'Q9JJV9': 'MANFLLPRGTSSFRRFTRESLAAIEKRMAEKQARGSATSQESREGLPEEEAPRPQLDLQASKKLPDLYGNPPRELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPVRRAAVKILVHSLFSMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARGFCLHAFTFLRDPWNWLDFSVIVMAYTTEFVDLGNVSALRTFRVLRALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNFTELNGTNGSVEADGIVWNSLDVYLNDPANYLLKNGTTDVLLCGNSSDAGTCPEGYRCLKAGENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYLVNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMSPLAPVTNHERRSKRRKRLSSGTEDGGDDRLPKSDSEDGPRALNQLSLTHGLSRTSMRPRSSRGSIFTFRRRDQGSEADFADDENSTAGESESHRTSLLVPWPLRRPSTQGQPGFGTSAPGHVLNGKRNSTVDCNGVVSLLGAGDAEATSPGSHLLRPIVLDRPPDTTTPSEEPGGPQMLTPQAPCADGFEEPGARQRALSAVSVLTSALEELEESHRKCPPCWNRFAQHYLIWECCPLWMSIKQKVKFVVMDPFADLTITMCIVLNTLFMALEHYNMTAEFEEMLQVGNLVFTGIFTAEMTFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMGNLSVLRSFRLLRVFKLAKSWPTLNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRHRISDSGLLPRWHMMDFFHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSADNLTAPDEDGEMNNLQLALARIQRGLRFVKRTTWDFCCGLLRRRPKKPAALATHSQLPSCIAAPRSPPPPEVEKAPPARKETRFEEDKRPGQGTPGDTEPVCVPIAVAESDTDDQEEDEENSLGTEEEESSKQESQVVSGGHEPPQEPRAWSQVSETTSSEAEASTSQADWQQEREAEPRAPGCGETPEDSYSEGSTADMTNTADLLEQIPDLGEDVKDPEDCFTEGCVRRCPCCMVDTTQAPGKVWWRLRKTCYRIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLVSLVANTLGFAEMGPIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCINQTEGDLPLNYTIVNNKSECESFNVTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIMYAAVDSRGYEEQPQWEDNLYMYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTMMVETDDQSPEKVNILAKINLLFVAIFTGECIVKMAALRHYYFTNSWNIFDFVVVILSIVGTVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGPPYCDPNLPNSNGSRGNCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEPLSEDDFDMFYEIWEKFDPEATQFIEYLALSDFADALSEPLRIAKPNQISLINMDLPMVSGDRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSATVIQRAFRRHLLQRSVKHASFLFRQQAGSSGLSDEDAPEREGLIAYMMNENFSRRSGPLSSSSISSTSFPPSYDSVTRATSDNLPVRASDYSRSEDLADFPPSPDRDRESIV'}; your molecule must be in SMILES format. [/INST]Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl |
[INST] Create new Small molecule for target with these components: {'Q15858': 'MAMLPPPGPQSFVHFTKQSLALIEQRIAERKSKEPKEEKKDDDEEAPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKTIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMNNPPDWTKNVEYTFTGIYTFESLVKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSIRRSRIMGLSESSSETSKLSSKSAKERRNRRKKKNQKKLSSGEEKGDAEKLSKSESEDSIRRKSFHLGVEGHRRAHEKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDIGSETEFADDEHSIFGDNESRRGSLFVPHRPQERRSSNISQASRSPPMLPVNGKMHSAVDCNGVVSLVDGRSALMLPNGQLLPEVIIDKATSDDSGTTNQIHKKRRCSSYLLSEDMLNDPNLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHKFLIWNCSPYWIKFKKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNVLAIGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINDDCTLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDPDANNLQIAVTRIKKGINYVKQTLREFILKAFSKKPKISREIRQAEDLNTKKENYISNHTLAEMSKGHNFLKEKDKISGFGSSVDKHLMEDSDGQSFIHNPSLTVTVPIAPGESDLENMNAEELSSDSDSEYSKVRLNRSSSSECSTVDNPLPGEGEEAEAEPMNSDEPEACFTDGCVWRFSCCQVNIESGKGKIWWNIRKTCYKIVEHSWFESFIVLMILLSSGALAFEDIYIERKKTIKIILEYADKIFTYIFILEMLLKWIAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECINTTDGSRFPASQVPNRSECFALMNVSQNVRWKNLKVNFDNVGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKIQGCIFDLVTNQAFDISIMVLICLNMVTMMVEKEGQSQHMTEVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVIISIVGMFLADLIETYFVSPTLFRVIRLARIGRILRLVKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEDGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEDVSATVIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLLNKKDMAFDNVNENSSPEKTDATSSTTSPPSYDSVTKPDKEKYEQDRTEKEDKGKDSKESKK', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F |
[INST] Create new Small molecule for target with these components: {'Q15858': 'MAMLPPPGPQSFVHFTKQSLALIEQRIAERKSKEPKEEKKDDDEEAPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKTIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMNNPPDWTKNVEYTFTGIYTFESLVKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSIRRSRIMGLSESSSETSKLSSKSAKERRNRRKKKNQKKLSSGEEKGDAEKLSKSESEDSIRRKSFHLGVEGHRRAHEKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDIGSETEFADDEHSIFGDNESRRGSLFVPHRPQERRSSNISQASRSPPMLPVNGKMHSAVDCNGVVSLVDGRSALMLPNGQLLPEVIIDKATSDDSGTTNQIHKKRRCSSYLLSEDMLNDPNLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHKFLIWNCSPYWIKFKKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNVLAIGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINDDCTLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDPDANNLQIAVTRIKKGINYVKQTLREFILKAFSKKPKISREIRQAEDLNTKKENYISNHTLAEMSKGHNFLKEKDKISGFGSSVDKHLMEDSDGQSFIHNPSLTVTVPIAPGESDLENMNAEELSSDSDSEYSKVRLNRSSSSECSTVDNPLPGEGEEAEAEPMNSDEPEACFTDGCVWRFSCCQVNIESGKGKIWWNIRKTCYKIVEHSWFESFIVLMILLSSGALAFEDIYIERKKTIKIILEYADKIFTYIFILEMLLKWIAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECINTTDGSRFPASQVPNRSECFALMNVSQNVRWKNLKVNFDNVGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKIQGCIFDLVTNQAFDISIMVLICLNMVTMMVEKEGQSQHMTEVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVIISIVGMFLADLIETYFVSPTLFRVIRLARIGRILRLVKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEDGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEDVSATVIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLLNKKDMAFDNVNENSSPEKTDATSSTTSPPSYDSVTKPDKEKYEQDRTEKEDKGKDSKESKK', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C,Cn1nccc1[C@@H]1CCCC[C@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)CC1 |
[INST] Create new Small molecule for target with these components: {'Q15858': 'MAMLPPPGPQSFVHFTKQSLALIEQRIAERKSKEPKEEKKDDDEEAPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKTIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMNNPPDWTKNVEYTFTGIYTFESLVKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSIRRSRIMGLSESSSETSKLSSKSAKERRNRRKKKNQKKLSSGEEKGDAEKLSKSESEDSIRRKSFHLGVEGHRRAHEKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDIGSETEFADDEHSIFGDNESRRGSLFVPHRPQERRSSNISQASRSPPMLPVNGKMHSAVDCNGVVSLVDGRSALMLPNGQLLPEVIIDKATSDDSGTTNQIHKKRRCSSYLLSEDMLNDPNLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHKFLIWNCSPYWIKFKKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNVLAIGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINDDCTLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQAMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDPDANNLQIAVTRIKKGINYVKQTLREFILKAFSKKPKISREIRQAEDLNTKKENYISNHTLAEMSKGHNFLKEKDKISGFGSSVDKHLMEDSDGQSFIHNPSLTVTVPIAPGESDLENMNAEELSSDSDSEYSKVRLNRSSSSECSTVDNPLPGEGEEAEAEPMNSDEPEACFTDGCVWRFSCCQVNIESGKGKIWWNIRKTCYKIVEHSWFESFIVLMILLSSGALAFEDIYIERKKTIKIILEYADKIFTYIFILEMLLKWIAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECINTTDGSRFPASQVPNRSECFALMNVSQNVRWKNLKVNFDNVGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKIQGCIFDLVTNQAFDISIMVLICLNMVTMMVEKEGQSQHMTEVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVIISIVGMFLADLIETYFVSPTLFRVIRLARIGRILRLVKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEDGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEDVSATVIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLLNKKDMAFDNVNENSSPEKTDATSSTTSPPSYDSVTKPDKEKYEQDRTEKEDKGKDSKESKK', 'O60939': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK', 'Q07699': 'MGRLLALVVGAALVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMIYCYKKIAAATETAAQENASEYLAITSESKENCTGVQVAE'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C,Cn1nccc1[C@@H]1CCCC[C@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,C[C@@H](c1cc(Cl)cc(Cl)c1)N1CCC(COc2cc(F)c(C(=O)NS(C)(=O)=O)cc2C2CC2)CC1,CS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(C3CC3)c(Cl)c2)cc1F,CS(=O)(=O)NC(=O)c1ccc2c(ccn2-c2ccccc2)c1,CS(=O)(=O)NC(=O)c1ccc2c(ccn2Cc2ccccc2)c1,CS(=O)(=O)NC(=O)c1ccc2[nH]cc(-c3ccccc3)c2c1,Cc1cn(-c2ccccc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cn1cc(-c2ccccc2)c2cc(C(=O)NS(C)(=O)=O)ccc21,Cc1cn(-c2ccccc2F)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(F)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(Cl)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(Cl)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,COc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,Cc1cn(-c2cccc(C(F)(F)F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cncc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(Cl)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2ccc(C(F)(F)F)nc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc12 |
[INST] Create new Unknown for target with these components: {'A6NNY8': 'MCKDYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQCSVPGLGEKFPTWETTKPELELLGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELCLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAANNPNHCNCIIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRHHKDQWFKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHESEKVKEMNTQAY'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Small molecule for target with these components: {'Q62205': 'MAMLPPPGPQSFVHFTKQSLALIEQRISEEKAKGHKDEKKDDEEEGPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKAIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRKDLEQNETLESIMSTAESEEELKRYFYYLEGSKDALLCGFSTDSGQCPEGYECVTAGRNPDYGYTSFDTFGWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSLGRSRIMGLSESSSETSRLSSKSAKERRNRRKKKKQKLSSGEEKGDDEKLSKSGSEESIRKKSFHLGVEGHHRAREKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDLGSETEFADDEHSIFGDNESRRGSLFVPHRPRERRSSNISQASRSPPVLPVNGKMHSAVDCNGVVSLVDGPSALMLPNGQLLPEVIIDKATSDDSGTTNQMRKKRLSSSYFLSEDMLNDPHLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHTFLIWNCSPYWIKFKKFIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTDEFKNVLAVGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINENCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDTDANNLQIAVARIKRGINYVKQTLREFILKSFSKKPKGSKDTKRTADPNNKRENYISNRTLAEISKDHNFLKEKDKISGFSSSLDKSFMDENDYQSFIHNPSLTVTVPIAPGESDLENMNTEELSSDSDSDYSKERRNRSSSSECSTVDNPLPGEEEAEAEPINADEPEACFTDGCVRRFPCCQVNIDSGKGKVWWTIRKTCYRIVEHSWFESFIVLMILLSSGALAFEDIYIEKKKTIKIILEYADKIFTYIFILEMLLKWVAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECVNTTDGSRFSVSQVANRSECFALMNVSGNVRWKNLKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSVNVNAQPIYEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGCIFDLVTNQAFDITIMVLICLNMVTMMVEKEGQTDYMSFVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEAGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSAPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEDVSATIIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLPNKEDIVFDNVNENSSPEKTDATASTISPPSYDSVTKPDQEKYETDKTEKEDKEKDESRK', 'P97952': 'MGTLLALVVGAALVSSAWGGCVEVDSDTEAVYGMTFKILCISCKRRSETTAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFDNYEHNTSVVKKIHLEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMVYCYKKIAAATEAAAQENASEYLAITSESKENCTGVQVAE', 'Q56A07': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTAPTTLSVLNGSDTRLPCTFNSCYTVNHKQFSLNWTYQECNNCTEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLEDEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKMDGEGNAEDGTK'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl |
[INST] Create new Small molecule for target with these components: {'Q62205': 'MAMLPPPGPQSFVHFTKQSLALIEQRISEEKAKGHKDEKKDDEEEGPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKAIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRKDLEQNETLESIMSTAESEEELKRYFYYLEGSKDALLCGFSTDSGQCPEGYECVTAGRNPDYGYTSFDTFGWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSLGRSRIMGLSESSSETSRLSSKSAKERRNRRKKKKQKLSSGEEKGDDEKLSKSGSEESIRKKSFHLGVEGHHRAREKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDLGSETEFADDEHSIFGDNESRRGSLFVPHRPRERRSSNISQASRSPPVLPVNGKMHSAVDCNGVVSLVDGPSALMLPNGQLLPEVIIDKATSDDSGTTNQMRKKRLSSSYFLSEDMLNDPHLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHTFLIWNCSPYWIKFKKFIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTDEFKNVLAVGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINENCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDTDANNLQIAVARIKRGINYVKQTLREFILKSFSKKPKGSKDTKRTADPNNKRENYISNRTLAEISKDHNFLKEKDKISGFSSSLDKSFMDENDYQSFIHNPSLTVTVPIAPGESDLENMNTEELSSDSDSDYSKERRNRSSSSECSTVDNPLPGEEEAEAEPINADEPEACFTDGCVRRFPCCQVNIDSGKGKVWWTIRKTCYRIVEHSWFESFIVLMILLSSGALAFEDIYIEKKKTIKIILEYADKIFTYIFILEMLLKWVAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECVNTTDGSRFSVSQVANRSECFALMNVSGNVRWKNLKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSVNVNAQPIYEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGCIFDLVTNQAFDITIMVLICLNMVTMMVEKEGQTDYMSFVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEAGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSAPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEDVSATIIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLPNKEDIVFDNVNENSSPEKTDATASTISPPSYDSVTKPDQEKYETDKTEKEDKEKDESRK', 'P97952': 'MGTLLALVVGAALVSSAWGGCVEVDSDTEAVYGMTFKILCISCKRRSETTAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFDNYEHNTSVVKKIHLEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMVYCYKKIAAATEAAAQENASEYLAITSESKENCTGVQVAE', 'Q56A07': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTAPTTLSVLNGSDTRLPCTFNSCYTVNHKQFSLNWTYQECNNCTEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLEDEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKMDGEGNAEDGTK'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C |
[INST] Create new Small molecule for target with these components: {'Q62205': 'MAMLPPPGPQSFVHFTKQSLALIEQRISEEKAKGHKDEKKDDEEEGPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKAIFRFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRKDLEQNETLESIMSTAESEEELKRYFYYLEGSKDALLCGFSTDSGQCPEGYECVTAGRNPDYGYTSFDTFGWAFLALFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSLGRSRIMGLSESSSETSRLSSKSAKERRNRRKKKKQKLSSGEEKGDDEKLSKSGSEESIRKKSFHLGVEGHHRAREKRLSTPNQSPLSIRGSLFSARRSSRTSLFSFKGRGRDLGSETEFADDEHSIFGDNESRRGSLFVPHRPRERRSSNISQASRSPPVLPVNGKMHSAVDCNGVVSLVDGPSALMLPNGQLLPEVIIDKATSDDSGTTNQMRKKRLSSSYFLSEDMLNDPHLRQRAMSRASILTNTVEELEESRQKCPPWWYRFAHTFLIWNCSPYWIKFKKFIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTDEFKNVLAVGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKINENCKLPRWHMNDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSDNLTAIEEDTDANNLQIAVARIKRGINYVKQTLREFILKSFSKKPKGSKDTKRTADPNNKRENYISNRTLAEISKDHNFLKEKDKISGFSSSLDKSFMDENDYQSFIHNPSLTVTVPIAPGESDLENMNTEELSSDSDSDYSKERRNRSSSSECSTVDNPLPGEEEAEAEPINADEPEACFTDGCVRRFPCCQVNIDSGKGKVWWTIRKTCYRIVEHSWFESFIVLMILLSSGALAFEDIYIEKKKTIKIILEYADKIFTYIFILEMLLKWVAYGYKTYFTNAWCWLDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECVNTTDGSRFSVSQVANRSECFALMNVSGNVRWKNLKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSVNVNAQPIYEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKFQGCIFDLVTNQAFDITIMVLICLNMVTMMVEKEGQTDYMSFVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVILSIVGMFLAEMIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEAGINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSAPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDSLRSQMEERFMSANPSKVSYEPITTTLKRKQEDVSATIIQRAYRRYRLRQNVKNISSIYIKDGDRDDDLPNKEDIVFDNVNENSSPEKTDATASTISPPSYDSVTKPDQEKYETDKTEKEDKEKDESRK', 'P97952': 'MGTLLALVVGAALVSSAWGGCVEVDSDTEAVYGMTFKILCISCKRRSETTAETFTEWTFRQKGTEEFVKILRYENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFDNYEHNTSVVKKIHLEVVDKANRDMASIVSEIMMYVLIVVLTIWLVAEMVYCYKKIAAATEAAAQENASEYLAITSESKENCTGVQVAE', 'Q56A07': 'MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTAPTTLSVLNGSDTRLPCTFNSCYTVNHKQFSLNWTYQECNNCTEEMFLQFRMKIINLKLERFGDRVEFSGNPSKYDVSVTLKNVQLEDEGIYNCYITNPPDRHRGHGKIYLQVLLEVPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEEEGKMDGEGNAEDGTK'}; your molecule must be in SMILES format. [/INST]CN1CC(n2nccc2-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1,Nc1[nH]ncc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cn1nccc1CCOc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ncns2)cc1F,Cc1nsc(NS(=O)(=O)c2cc(F)c(O[C@H]3CCC[C@@H]3c3ccnn3C)cc2F)n1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2nccs2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2cscn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1c(F)cc(S(=O)(=O)Nc2ccncn2)cc1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1ccc(S(=O)(=O)Nc2ccncn2)c(F)c1F,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCCCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)c(F)c1,Cn1nccc1[C@H]1CCC[C@@H]1Oc1cc(F)c(S(=O)(=O)Nc2ccncn2)cc1Cl,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCC[C@@H]1c1ccnn1C,Cc1cc(S(=O)(=O)Nc2ccncn2)c(F)cc1O[C@H]1CCCC[C@@H]1c1ccnn1C,CS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(C3CC3)c(Cl)c2)cc1F,CS(=O)(=O)NC(=O)c1ccc2c(ccn2-c2ccccc2)c1,CS(=O)(=O)NC(=O)c1ccc2c(ccn2Cc2ccccc2)c1,CS(=O)(=O)NC(=O)c1ccc2[nH]cc(-c3ccccc3)c2c1,Cc1cn(-c2ccccc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cn1cc(-c2ccccc2)c2cc(C(=O)NS(C)(=O)=O)ccc21,Cc1cn(-c2ccccc2F)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(F)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(Cl)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2ccc(Cl)cc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,COc1cccc(-n2cc(C)c3cc(C(=O)NS(C)(=O)=O)ccc32)c1,Cc1cn(-c2cccc(C(F)(F)F)c2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cccc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cccnc2)c2ccc(C(=O)NS(C)(=O)=O)cc12,Cc1cn(-c2cncc(F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(Cl)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2ccc(C(F)(F)F)nc2)c2ccc(C(=O)NS(=O)(=O)C3CC3)cc12,Cc1cn(-c2cncc(C(F)(F)F)c2)c2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc12 |
[INST] Create new Unknown for target with these components: {'O70305': 'MRSSTAAVQRPAAGDPEPRRPAGWAARRSLPRTARRGGRGGAVAYPSAGPPPRGPGAPPRGPRSPPCASDCFGSNGHGASRPGSRRLLGVCGPPRPFVVVLLALAPAATPARACPPGVRASPPRSGVSSSARPAPGCPRPACEPVYGPLTMSLKPQPQPPAPATGRKPGGGLLSSPGAAPASAAVTSASVVPAPAAPVASSSAAAGGGRPGLGRGRNSSKGLPQPTISFDGIYANVRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESVLFKCSDFVVVQFKDTDSSYARRDAFTDSALSAKVNGEHKEKDLEPWDAGELTASEELELENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNCSDREGHGPNTRDNKYIPPGQRNREVLSWGSGRQSSPRMGQPGPGSMPSRAASHTSDFNPNAGSDQRVVNGGVPWPSPCPSHSSRPPSRYQSGPNSLPPRAATHTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSMSSGLEFVSHNPPSEAAAPPVARTSPAGGTWSSVVSGVPRLSPKTHRPRSPRQSSIGNSPSGPVLASPQAGIIPAEAVSMPVPAASPTPASPASNRALTPSIEAKDSRLQDQRQNSPAGSKENVKASETSPSFSKADNKGMSPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLSKNREGEKSRDLIKDKTEASAKDSFIDSSSSSSNCTSGSSKTNSPSISPSMLSNAEHKRGPEVTSQGVQTSSPACKQEKDDREEKKDTTEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPAPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGKVPNMPQQRQDQHHQSTMMHPASAAGPPIVATPPAYSTQYVAYSPQQFPNQPLVQHVPHYQSQHPHVYSPVIQGNARMMAPPAHAQPGLVSSSAAQFGAHEQTHAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHPNAALHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQSSFPAAQQTVFTIHPSHVQPAYTTPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGPKAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL'}; your molecule must be in SMILES format. [/INST]O=C(O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1,O=C(O)c1ccc(COc2ccc(CNC(=O)[C@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1,O=C(O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccc(Br)cc3)cc2)cc1,O=C(O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccc(F)cc3)cc2)cc1,O=C(O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccc(C(F)(F)F)cc3)cc2)cc1,O=C1CC[C@@H](C(=O)NCc2ccc(OCc3ccc(C(=O)O)cc3)cc2)N1,COC(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1,NS(=O)(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1,NS(=O)(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccc(F)cc3)cc2)cc1,NS(=O)(=O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccc(C(F)(F)F)cc3)cc2)cc1,CC1(C)OB(c2ccc(COc3ccc(CNC(=O)[C@@H]4CCC(=O)N4Cc4ccccc4)cc3)cc2)OC1(C)C,CC1(C)OB(c2ccc(COc3ccc(CNC(=O)[C@@H]4CCC(=O)N4Cc4ccc(F)cc4)cc3)cc2)OC1(C)C,CC1(C)OB(c2ccc(COc3ccc(CNC(=O)[C@H]4CCC(=O)N4Cc4ccccc4)cc3)cc2)OC1(C)C,O=C(NCc1ccc(OCc2ccccc2)cc1)[C@@H]1CCC(=O)N1Cc1ccccc1,Cl.O=C(NCCc1c[nH]cn1)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1,Cl.O=C(NCCc1c[nH]cn1)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccc(F)cc3)cc2)cc1,O=C(NO)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCC(=O)N3Cc3ccccc3)cc2)cc1,O=C(NCc1ccc(OCc2ccc(-c3nn[nH]n3)cc2)cc1)[C@@H]1CCC(=O)N1Cc1ccccc1,O=C(NCc1ccc(OCc2ccc(-c3nn[nH]n3)cc2)cc1)[C@@H]1CCC(=O)N1Cc1ccc(F)cc1,O=C(NCc1ccc(OCc2cn(-c3ccccc3)nn2)cc1)[C@@H]1CCC(=O)N1Cc1ccccc1,O=C(NCc1ccc(OCc2ccncc2)cc1)[C@@H]1CCC(=O)N1Cc1ccccc1,O=C(NCc1ccc(OCc2ccc(B(O)O)cc2)cc1)[C@@H]1CCC(=O)N1Cc1ccccc1,O=C(O)c1ccc(COc2ccc(CN3C(=O)CC[C@H]3C(=O)NCc3ccccc3)cc2)cc1,O=C(NCc1ccccc1)[C@@H]1CCC(=O)N1Cc1ccc(OCc2ccc(-c3nn[nH]n3)cc2)cc1,NS(=O)(=O)c1ccc(C(=O)NC[C@@H]2CCC(=O)N2Cc2ccccc2)cc1,COC(=O)c1ccc(COc2ccc(CN3C(=O)CC[C@H]3Cn3ccnc3)cc2)cc1,O=C(O)c1ccc(COc2ccc(CN3C(=O)CC[C@H]3Cn3ccnc3)cc2)cc1,O=C(NCc1ccccc1)[C@@H]1CCC(=O)N1Cc1ccccc1,O=C(NCc1ccc(O)cc1)[C@@H]1CCC(=O)N1Cc1ccccc1,O=C(O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCCN3Cc3ccccc3)cc2)cc1,O=C(O)c1ccc(COc2ccc(CNC(=O)[C@@H]3CCCN3Cc3ccc(F)cc3)cc2)cc1,O=C(O)c1ccc(COc2ccc(CNC(=O)[C@H]3CCCN3Cc3ccc(F)cc3)cc2)cc1,O=C(NCc1ccc(OCc2ccc(-c3nn[nH]n3)cc2)cc1)[C@@H]1CCCN1Cc1ccccc1,O=C(O)c1ccc(COc2ccc(CN3CCC[C@H]3C(=O)NCc3ccccc3)cc2)cc1,O=C(NCc1ccccc1)[C@@H]1CCCN1Cc1ccc(OCc2ccc(-c3nn[nH]n3)cc2)cc1 |
[INST] Create new Small molecule for target with these components: {'O75807': 'MAPGQAPHQATPWRDAHPFFLLSPVMGLLSRAWSRLRGLGPLEPWLVEAVKGAALVEAGLEGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQEELSPCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSSAAAAAALDLSGRRG'}; your molecule must be in SMILES format. [/INST]N=C(N)N/N=C/c1cccc(Cl)c1Cl |
[INST] Create new Unknown for target with these components: {'P04186': 'MESPQLCLVLLVLGFSSGGVSATPVLEARPQVSCSLEGVEIKGGSFQLLQGGQALEYLCPSGFYPYPVQTRTCRSTGSWSDLQTRDQKIVQKAECRAIRCPRPQDFENGEFWPRSPFYNLSDQISFQCYDGYVLRGSANRTCQENGRWDGQTAICDDGAGYCPNPGIPIGTRKVGSQYRLEDIVTYHCSRGLVLRGSQKRKCQEGGSWSGTEPSCQDSFMYDSPQEVAEAFLSSLTETIEGADAEDGHSPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGSSNFTGAKRCLTNLIEKVASYGVRPRYGLLTYATVPKVLVRVSDERSSDADWVTEKLNQISYEDHKLKSGTNTKRALQAVYSMMSWAGDAPPEGWNRTRHVIIIMTDGLHNMGGNPVTVIQDIRALLDIGRDPKNPREDYLDVYVFGVGPLVDSVNINALASKKDNEHHVFKVKDMEDLENVFYQMIDETKSLSLCGMVWEHKKGNDYHKQPWQAKISVTRPLKGHETCMGAVVSEYFVLTAAHCFMVDDQKHSIKVSVGGQRRDLEIEEVLFHPKYNINGKKAEGIPEFYDYDVALVKLKNKLKYGQTLRPICLPCTEGTTRALRLPQTATCKQHKEQLLPVKDVKALFVSEQGKSLTRKEVYIKNGDKKASCERDATKAQGYEKVKDASEVVTPRFLCTGGVDPYADPNTCKGDSGGPLIVHKRSRFIQVGVISWGVVDVCRDQRRQQLVPSYARDFHINLFQVLPWLKDKLKDEDLGFL'}; your molecule must be in SMILES format. [/INST]Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(C(=O)O)cc1,CO[C@H]1CCN(Cc2c(C)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1,CO[C@H]1CCN(Cc2c(C3CC3)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1,COc1cc(C)c2[nH]ccc2c1CN1CC[C@H](OC)C[C@H]1c1ccc(C(=O)O)cc1,CCO[C@H]1CCN(Cc2c(C)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1,CCO[C@H]1CCN(Cc2c(C3CC3)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1 |
[INST] Create new Unknown for target with these components: {'P04186': 'MESPQLCLVLLVLGFSSGGVSATPVLEARPQVSCSLEGVEIKGGSFQLLQGGQALEYLCPSGFYPYPVQTRTCRSTGSWSDLQTRDQKIVQKAECRAIRCPRPQDFENGEFWPRSPFYNLSDQISFQCYDGYVLRGSANRTCQENGRWDGQTAICDDGAGYCPNPGIPIGTRKVGSQYRLEDIVTYHCSRGLVLRGSQKRKCQEGGSWSGTEPSCQDSFMYDSPQEVAEAFLSSLTETIEGADAEDGHSPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGSSNFTGAKRCLTNLIEKVASYGVRPRYGLLTYATVPKVLVRVSDERSSDADWVTEKLNQISYEDHKLKSGTNTKRALQAVYSMMSWAGDAPPEGWNRTRHVIIIMTDGLHNMGGNPVTVIQDIRALLDIGRDPKNPREDYLDVYVFGVGPLVDSVNINALASKKDNEHHVFKVKDMEDLENVFYQMIDETKSLSLCGMVWEHKKGNDYHKQPWQAKISVTRPLKGHETCMGAVVSEYFVLTAAHCFMVDDQKHSIKVSVGGQRRDLEIEEVLFHPKYNINGKKAEGIPEFYDYDVALVKLKNKLKYGQTLRPICLPCTEGTTRALRLPQTATCKQHKEQLLPVKDVKALFVSEQGKSLTRKEVYIKNGDKKASCERDATKAQGYEKVKDASEVVTPRFLCTGGVDPYADPNTCKGDSGGPLIVHKRSRFIQVGVISWGVVDVCRDQRRQQLVPSYARDFHINLFQVLPWLKDKLKDEDLGFL'}; your molecule must be in SMILES format. [/INST]Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(C(=O)O)cc1,CO[C@H]1CCN(Cc2c(C)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1,CO[C@H]1CCN(Cc2c(C3CC3)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1,COc1cc(C)c2[nH]ccc2c1CN1CC[C@H](OC)C[C@H]1c1ccc(C(=O)O)cc1,CCO[C@H]1CCN(Cc2c(C)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1,CCO[C@H]1CCN(Cc2c(C3CC3)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1,CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@H](c2ccc(C(=O)O)cc2)C1 |
[INST] Create new Unknown for target with these components: {'P05307': 'MLRRALLCLALTALFRAGAGAPDEEDHVLVLHKGNFDEALAAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKFFKNGDTASPKEYTAGREADDIVNWLKKRTGPAASTLSDGAAAEALVESSEVAVIGFFKDMESDSAKQFFLAAEVIDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEVTKEKLLDFIKHNQLPLVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYEGKLSNFKKAAESFKGKILFIFIDSDHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQELPDDWDKQPVKVLVGKNFEEVAFDEKKNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVIDYNGERTLDGFKKFLESGGQDGAGDDDDLEDLEEAEEPDLEEDDDQKAVKDEL'}; your molecule must be in SMILES format. [/INST]C#CCOC(=O)C1(C)c2[nH]c3ccccc3c2CCN1C(=O)CCl |
[INST] Create new Unknown for target with these components: {'P07996': 'MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDP'}; your molecule must be in SMILES format. [/INST]CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N(C)[C@@H](CC(C)C)C(N)=O,CC(=O)NCCCC[C@H](NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(N)=O,CNCCCC[C@H](NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N(C)C,CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](NC(C)=O)[C@@H](C)O,CCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CC(C)C)C(N)=O,CC(=O)N[C@@H](CO)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)N[C@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(N)=O,CC(=O)N[C@@H](CCCN)C(=O)NC(C)(C)C(N)=O |
[INST] Create new Unknown for target with these components: {'P32750': 'NTDQSFPGFPGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSVNYRVGALGFLALPGNPEAPGNLGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVGLHL'}; your molecule must be in SMILES format. [/INST]COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCN4CCCC4)cc3)s2)cc1OC,COc1cc(CC(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc(OC)c1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc1,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(C(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCN4CCCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCSc4ccncc4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCN4CCN(Cc5ccccc5)CC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCNC4CCN(Cc5ccccc5)CC4)cc3)s2)cc1OC |
[INST] Create new Unknown for target with these components: {'P32750': 'NTDQSFPGFPGSEMWNPNTDLSEDCLYLNVWIPTPKPKNATVMIWIYGGGFQTGTSSLPVYDGKFLARVERVIVVSVNYRVGALGFLALPGNPEAPGNLGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAGSVGLHL'}; your molecule must be in SMILES format. [/INST]COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCN4CCCC4)cc3)s2)cc1OC,COc1cc(CC(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc(OC)c1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc1,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(C(=O)Nc2ncc(-c3ccc(OCCCN4CCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCN4CCCCC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCSc4ccncc4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCN4CCN(Cc5ccccc5)CC4)cc3)s2)cc1OC,COc1ccc(CC(=O)Nc2ncc(-c3ccc(OCCCCNC4CCN(Cc5ccccc5)CC4)cc3)s2)cc1OC,CCN(C)C(=O)Oc1cccc([C@H](C)N(C)C)c1,C/C=C1\[C@H]2C=C(C)C[C@]1(N)c1ccc(=O)[nH]c1C2 |
[INST] Create new Unknown for target with these components: {'P35125': 'MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVGINSSIDRFGILHETELPPVTAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEIKLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYSEYNPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQQEHVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLMPITSIALKVQQKRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPAKREQGSLAPRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAVREDTYPVGTQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVRAISQEDQLATCWQAEHCGEVHNKDMSWPEEMSFTANSSKIDRQKVPTEKGATGLSNLGNTCFMNSSIQCVSNTQPLTQYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFDGFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIIVDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLEITVIKLDGTTPVRYGLRLNMDEKYTGLKKQLRDLCGLNSEQILLAEVHDSNIKNFPQDNQKVQLSVSGFLCAFEIPVPSSPISASSPTQIDFSSSPSTNGMFTLTTNGDLPKPIFIPNGMPNTVVPCGTEKNFTNGMVNGHMPSLPDSPFTGYIIAVHRKMMRTELYFLSPQENRPSLFGMPLIVPCTVHTRKKDLYDAVWIQVSWLARPLPPQEASIHAQDRDNCMGYQYPFTLRVVQKDGNSCAWCPQYRFCRGCKIDCGEDRAFIGNAYIAVDWHPTALHLRYQTSQERVVDKHESVEQSRRAQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQFVNDQWIKSQKIVRFLRESFDPSAFLVPRDPALCQHKPLTPQGDELSKPRILAREVKKVDAQSSAGKEDMLLSKSPSSLSANISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTLGRSKGRLRLPQIGSKNKPSSSKKNLDASKENGAGQICELADALSRGHMRGGSQPELVTPQDHEVALANGFLYEHEACGNGCGDGYSNGQLGNHSEEDSTDDQREDTHIKPIYNLYAISCHSGILSGGHYITYAKNPNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQGIDYAQFLPKIDGKKMADTSSTDEDSESDYEKYSMLQ'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Small molecule for target with these components: {'P36956': 'MDEPPFSEAALEQALGEPCDLDAALLTDIEDMLQLINNQDSDFPGLFDPPYAGSGAGGTDPASPDTSSPGSLSPPPATLSSSLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQPLPGLPLASPPGVPPVSLHTQVQSVVPQQLLTVTAAPTAAPVTTTVTSQIQQVPVLLQPHFIKADSLLLTAMKTDGATVKAAGLSPLVSGTTVQTGPLPTLVSGGTILATVPLVVDAEKLPINRLAAGSKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLSLRTAVHKSKSLKDLVSACGSGGNTDVLMEGVKTEVEDTLTPPPSDAGSPFQSSPLSLGSRGSGSGGSGSDSEPDSPVFEDSKAKPEQRPSLHSRGMLDRSRLALCTLVFLCLSCNPLASLLGARGLPSPSDTTSVYHSPGRNVLGTESRDGPGWAQWLLPPVVWLLNGLLVLVSLVLLFVYGEPVTRPHSGPAVYFWRHRKQADLDLARGDFAQAAQQLWLALRALGRPLPTSHLDLACSLLWNLIRHLLQRLWVGRWLAGRAGGLQQDCALRVDASASARDAALVYHKLHQLHTMGKHTGGHLTATNLALSALNLAECAGDAVSVATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPPAMQWLCHPVGHRFFVDGDWSVLSTPWESLYSLAGNPVDPLAQVTQLFREHLLERALNCVTQPNPSPGSADGDKEFSDALGYLQLLNSCSDAAGAPAYSFSISSSMATTTGVDPVAKWWASLTAVVIHWLRRDEEAAERLCPLVEHLPRVLQESERPLPRAALHSFKAARALLGCAKAESGPASLTICEKASGYLQDSLATTPASSSIDKAVQLFLCDLLLVVRTSLWRQQQPPAPAPAAQGTSSRPQASALELRGFQRDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPTRTHQLLDRSLRRRAGPGGKGGAVAELEPRPTRREHAEALLLASCYLPPGFLSAPGQRVGMLAEAARTLEKLGDRRLLHDCQQMLMRLGGGTTVTSS'}; your molecule must be in SMILES format. [/INST]C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@@H]12,CCCc1cc(-c2nc(-c3ccc(NS(C)(=O)=O)cc3)cs2)ccn1,CCc1cc(-c2nc(-c3ccc(C)cc3)cs2)ccn1 |
[INST] Create new Small molecule for target with these components: {'P36956': 'MDEPPFSEAALEQALGEPCDLDAALLTDIEDMLQLINNQDSDFPGLFDPPYAGSGAGGTDPASPDTSSPGSLSPPPATLSSSLEAFLSGPQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSFPAPAPPQFSSTPVLGYPSPPGGFSTGSPPGNTQQPLPGLPLASPPGVPPVSLHTQVQSVVPQQLLTVTAAPTAAPVTTTVTSQIQQVPVLLQPHFIKADSLLLTAMKTDGATVKAAGLSPLVSGTTVQTGPLPTLVSGGTILATVPLVVDAEKLPINRLAAGSKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVVGTEAKLNKSAVLRKAIDYIRFLQHSNQKLKQENLSLRTAVHKSKSLKDLVSACGSGGNTDVLMEGVKTEVEDTLTPPPSDAGSPFQSSPLSLGSRGSGSGGSGSDSEPDSPVFEDSKAKPEQRPSLHSRGMLDRSRLALCTLVFLCLSCNPLASLLGARGLPSPSDTTSVYHSPGRNVLGTESRDGPGWAQWLLPPVVWLLNGLLVLVSLVLLFVYGEPVTRPHSGPAVYFWRHRKQADLDLARGDFAQAAQQLWLALRALGRPLPTSHLDLACSLLWNLIRHLLQRLWVGRWLAGRAGGLQQDCALRVDASASARDAALVYHKLHQLHTMGKHTGGHLTATNLALSALNLAECAGDAVSVATLAEIYVAAALRVKTSLPRALHFLTRFFLSSARQACLAQSGSVPPAMQWLCHPVGHRFFVDGDWSVLSTPWESLYSLAGNPVDPLAQVTQLFREHLLERALNCVTQPNPSPGSADGDKEFSDALGYLQLLNSCSDAAGAPAYSFSISSSMATTTGVDPVAKWWASLTAVVIHWLRRDEEAAERLCPLVEHLPRVLQESERPLPRAALHSFKAARALLGCAKAESGPASLTICEKASGYLQDSLATTPASSSIDKAVQLFLCDLLLVVRTSLWRQQQPPAPAPAAQGTSSRPQASALELRGFQRDLSSLRRLAQSFRPAMRRVFLHEATARLMAGASPTRTHQLLDRSLRRRAGPGGKGGAVAELEPRPTRREHAEALLLASCYLPPGFLSAPGQRVGMLAEAARTLEKLGDRRLLHDCQQMLMRLGGGTTVTSS'}; your molecule must be in SMILES format. [/INST]C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)(C)O)CC[C@@H]12,CCCc1cc(-c2nc(-c3ccc(NS(C)(=O)=O)cc3)cs2)ccn1,CCc1cc(-c2nc(-c3ccc(C)cc3)cs2)ccn1,C[C@H](CCC(F)(F)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/Cn3nnc(-c4ccc(F)cc4)n3)CCC[C@]12C,C[C@H](CCC(F)(F)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/Cn3nnnc3-c3ccccc3)CCC[C@]12C,C[C@H](CCC(F)(F)C(C)(C)O)[C@H]1CC[C@H]2/C(=C/Cn3nnnc3-c3ccc(F)cc3)CCC[C@]12C |
[INST] Create new Unknown for target with these components: {'P51784': 'MAVAPRLFGGLCFRFRDQNPEVAVEGRLPISHSCVGCRRERTAMATVAANPAAAAAAVAAAAAVTEDREPQHEELPGLDSQWRQIENGESGRERPLRAGESWFLVEKHWYKQWEAYVQGGDQDSSTFPGCINNATLFQDEINWRLKEGLVEGEDYVLLPAAAWHYLVSWYGLEHGQPPIERKVIELPNIQKVEVYPVELLLVRHNDLGKSHTVQFSHTDSIGLVLRTARERFLVEPQEDTRLWAKNSEGSLDRLYDTHITVLDAALETGQLIIMETRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPISHKRVLEVFFIPMDPRRKPEQHRLVVPKKGKISDLCVALSKHTGISPERMMVADVFSHRFYKLYQLEEPLSSILDRDDIFVYEVSGRIEAIEGSREDIVVPVYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDRFTWEGLYNVLMYRLSRYVTKPNSDDEDDGDEKEDDEEDKDDVPGPSTGGSLRDPEPEQAGPSSGVTNRCPFLLDNCLGTSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEVHAQPYIAIDWEPEMKKRYYDEVEAEGYVKHDCVGYVMKKAPVRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVARRLLSPAGSSGAPASPACSSPPSSEFMDVN'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Small molecule for target with these components: {'P53539': 'MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSYTSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL'}; your molecule must be in SMILES format. [/INST]COc1cccc2c1NC(C(=O)O)C1CC=CC21 |
[INST] Create new Small molecule for target with these components: {'P53539': 'MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTAITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGSGGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRDLPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSYTSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL'}; your molecule must be in SMILES format. [/INST]COc1cccc2c1NC(C(=O)O)C1CC=CC21,CCOC(=O)C1Nc2c(OC)cccc2C2C=CCC12,CNC(=O)C1Nc2c(OC)cccc2C2C=CCC12,COc1cccc2c1NC(C(=O)Nc1ccccc1)C1CC=CC21,COc1cccc2c1NC(CO)C1CC=CC21,COc1cccc2c1N(C(C)=O)C(C(=O)O)C1CC=CC21,COc1cccc2c1NC(C(=O)O)C1CCCC21,Cc1cccc2c1NC(C(=O)O)C1CC=CC21,CCOC(=O)c1nc2c(C)cccc2c2c1CCC2,Cc1cccc2c3c(c(C(=O)O)nc12)CCC3,COc1cc(OC)c2c(C(=O)O)nc3c(OC)cccc3c2c1,COc1cc(OC)c2c(C3CCN(C(=O)OC(C)(C)C)CC3)nc3c(OC)cccc3c2c1,COc1cc(OC)c2c(C3CCNCC3)nc3c(OC)cccc3c2c1,COc1cc(OC)c2c(C3CCN(C(C)=O)CC3)nc3c(OC)cccc3c2c1,CCc1nc2c(OC)cccc2c2cc(OC)cc(OC)c12 |
[INST] Create new Unknown for target with these components: {'Q03393': 'MSTEGGGRRCQAQVSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVLPVGVLYKVKVYETDNNIVVYKGE'}; your molecule must be in SMILES format. [/INST]CN(C)c1cc(O)c(C(=O)O)cc1C#Cc1cccc(NC(=O)C(=O)O)c1,O=C(O)C(=O)Nc1ccc(C#Cc2ccc(C(F)(F)F)cc2)cc1,O=C(O)C(=O)Nc1ccc(C#Cc2ccc(C(F)(F)F)cc2Cl)cc1 |
[INST] Create new Unknown for target with these components: {'Q15040': 'MSCVPWKGDKAKSESLELPQAAPPQIYHEKQRRELCALHALNNVFQDSNAFTRDTLQEIFQRLSPNTMVTPHKKSMLGNGNYDVNVIMAALQTKGYEAVWWDKRRDVGVIALTNVMGFIMNLPSSLCWGPLKLPLKRQHWICVREVGGAYYNLDSKLKMPEWIGGESELRKFLKHHLRGKNCELLLVVPEEVEAHQSWRTDV'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Small molecule for target with these components: {'Q5SWA1': 'MEPGTGGSRKRLGPRAGFRFWPPFFPRRSQAGSSKFPTPLGPENSGNPTLLSSAQPETRVSYWTKLLSQLLAPLPGLLQKVLIWSQLFGGMFPTRWLDFAGVYSALRALKGREKPAAPTAQKSLSSLQLDSSDPSVTSPLDWLEEGIHWQYSPPDLKLELKAKGSALDPAAQAFLLEQQLWGVELLPSSLQSRLYSNRELGSSPSGPLNIQRIDNFSVVSYLLNPSYLDCFPRLEVSYQNSDGNSEVVGFQTLTPESSCLREDHCHPQPLSAELIPASWQGCPPLSTEGLPEIHHLRMKRLEFLQQASKGQDLPTPDQDNGYHSLEEEHSLLRMDPKHCRDNPTQFVPAAGDIPGNTQESTEEKIELLTTEVPLALEEESPSEGCPSSEIPMEKEPGEGRISVVDYSYLEGDLPISARPACSNKLIDYILGGASSDLETSSDPEGEDWDEEAEDDGFDSDSSLSDSDLEQDPEGLHLWNSFCSVDPYNPQNFTATIQTAARIVPEEPSDSEKDLSGKSDLENSSQSGSLPETPEHSSGEEDDWESSADEAESLKLWNSFCNSDDPYNPLNFKAPFQTSGENEKGCRDSKTPSESIVAISECHTLLSCKVQLLGSQESECPDSVQRDVLSGGRHTHVKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEDAIGYCLTFEHRERMFNRLQGTCFKGLNVLKQC'}; your molecule must be in SMILES format. [/INST]N=C(N)N/N=C/c1cccc(Cl)c1Cl |
[INST] Create new Unknown for target with these components: {'Q5T2D3': 'MSRKQAAKSRPGSGSRKAEAERKRDERAARRALAKERRNRPESGGGGGCEEEFVSFANQLQALGLKLREVPGDGNCLFRALGDQLEGHSRNHLKHRQETVDYMIKQREDFEPFVEDDIPFEKHVASLAKPGTFAGNDAIVAFARNHQLNVVIHQLNAPLWQIRGTEKSSVRELHIAYRYGEHYDSVRRINDNSEAPAHLQTDFQMLHQDESNKREKIKTKGMDSEDDLRDEVEDAVQKVCNATGCSDFNLIVQNLEAENYNIESAIIAVLRMNQGKRNNAEENLEPSGRVLKQCGPLWEEGGSGARIFGNQGLNEGRTENNKAQASPSEENKANKNQLAKVTNKQRREQQWMEKKKRQEERHRHKALESRGSHRDNNRSEAEANTQVTLVKTFAALNI'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q5VV17': 'MQLYSSVCTHYPAGAPGPTAAAPAPPAAATPFKVSLQPPGAAGAAPEPETGECQPAAAAEHREAAAVPAAKMPAFSSCFEVVSGAAAPASAAAGPPGASCKPPLPPHYTSTAQITVRALGADRLLLHGPDPVPGAAGSAAAPRGRCLLLAPAPAAPVPPRRGSSAWLLEELLRPDCPEPAGLDATREGPDRNFRLSEHRQALAAAKHRGPAATPGSPDPGPGPWGEEHLAERGPRGWERGGDRCDAPGGDAARRPDPEAEAPPAGSIEAAPSSAAEPVIVSRSDPRDEKLALYLAEVEKQDKYLRQRNKYRFHIIPDGNCLYRAVSKTVYGDQSLHRELREQTVHYIADHLDHFSPLIEGDVGEFIIAAAQDGAWAGYPELLAMGQMLNVNIHLTTGGRLESPTVSTMIHYLGPEDSLRPSIWLSWLSNGHYDAVFDHSYPNPEYDNWCKQTQVQRKRDEELAKSMAISLSKMYIEQNACS'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q5VVQ6': 'MFGPAKGRHFGVHPAPGFPGGVSQQAAGTKAGPAGAWPVGSRTDTMWRLRCKAKDGTHVLQGLSSRTRVRELQGQIAAITGIAPGGQRILVGYPPECLDLSNGDTILEDLPIQSGDMLIIEEDQTRPRSSPAFTKRGASSYVRETLPVLTRTVVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVASDPDFYSEAILGKTNQEYCDWIKRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTKRVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRRRQFTDVNRFTLRCMVCQKGLTGQAEAREHAKETGHTNFGEV'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q61176': 'MSSKPKSLEIIGAPFSKGQPRGGVEKGPAALRKAGLLEKLKETEYDVRDHGDLAFVDVPNDSSFQIVKNPRSVGKANEELAGVVAEVQKNGRVSVVLGGDHSLAVGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVSFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPAFTPATGTPVLGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTAEEVKSTVNTAVALTLACFGTQREGNHKPGTDYLKPPK'}; your molecule must be in SMILES format. [/INST]N[C@@]1(C(=O)O)C[C@H]2CNC[C@H]2[C@@H]1CCCB(O)O |
[INST] Create new Unknown for target with these components: {'Q61176': 'MSSKPKSLEIIGAPFSKGQPRGGVEKGPAALRKAGLLEKLKETEYDVRDHGDLAFVDVPNDSSFQIVKNPRSVGKANEELAGVVAEVQKNGRVSVVLGGDHSLAVGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVSFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPAFTPATGTPVLGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTAEEVKSTVNTAVALTLACFGTQREGNHKPGTDYLKPPK'}; your molecule must be in SMILES format. [/INST]N[C@@]1(C(=O)O)C[C@H]2CNC[C@H]2[C@@H]1CCCB(O)O,OC[C@H]1O[C@H](Oc2cc(/C=C/c3cc(O)cc(O)c3)ccc2O)[C@H](O)[C@@H](O)[C@@H]1O |
[INST] Create new Unknown for target with these components: {'Q6GQQ9': 'MTLDMDAVLSDFVRSTGAEPGLARDLLEGKNWDVNAALSDFEQLRQVHAGNLPPSFSEGSGGSRTPEKGFSDREPTRPPRPILQRQDDIVQEKRLSRGISHASSSIVSLARSHVSSNGGGGGSNEHPLEMPICAFQLPDLTVYNEDFRSFIERDLIEQSMLVALEQAGRLNWWVSVDPTSQRLLPLATTGDGNCLLHAASLGMWGFHDRDLMLRKALYALMEKGVEKEALKRRWRWQQTQQNKESGLVYTEDEWQKEWNELIKLASSEPRMHLGTNGANCGGVESSEEPVYESLEEFHVFVLAHVLRRPIVVVADTMLRDSGGEAFAPIPFGGIYLPLEVPASQCHRSPLVLAYDQAHFSALVSMEQKENTKEQAVIPLTDSEYKLLPLHFAVDPGKGWEWGKDDSDNVRLASVILSLEVKLHLLHSYMNVKWIPLSSDAQAPLAQPESPTASAGDEPRSTPESGDSDKESVGSSSTSNEGGRRKEKSKRDREKDKKRADSVANKLGSFGKTLGSKLKKNMGGLMHSKGSKPGGVGTGLGGSSGTETLEKKKKNSLKSWKGGKEEAAGDGPVSEKPPAESVGNGGSKYSQEVMQSLSILRTAMQGEGKFIFVGTLKMGHRHQYQEEMIQRYLSDAEERFLAEQKQKEAERKIMNGGIGGGPPPAKKPEPDAREEQPTGPPAESRAMAFSTGYPGDFTIPRPSGGGVHCQEPRRQLAGGPCVGGLPPYATFPRQCPPGRPYPHQDSIPSLEPGSHSKDGLHRGALLPPPYRVADSYSNGYREPPEPDGWAGGLRGLPPTQTKCKQPNCSFYGHPETNNFCSCCYREELRRREREPDGELLVHRF'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q6IQ20': 'MDENESNQSLMTSSQYPKEAVRKRQNSARNSGASDSSRFSRKSFKLDYRLEEDVTKSKKGKDGRFVNPWPTWKNPSIPNVLRWLIMEKDHSSVPSSKEELDKELPVLKPYFITNPEEAGVREAGLRVTWLGHATVMVEMDELIFLTDPIFSSRASPSQYMGPKRFRRSPCTISELPPIDAVLISHNHYDHLDYNSVIALNERFGNELRWFVPLGLLDWMQKCGCENVIELDWWEENCVPGHDKVTFVFTPSQHWCKRTLMDDNKVLWGSWSVLGPWNRFFFAGDTGYCPAFEEIGKRFGPFDLAAIPIGAYEPRWFMKYQHVDPEEAVRIHTDVQTKKSMAIHWGTFALANEHYLEPPVKLNEALERYGLNAEDFFVLKHGESRYLNNDDENF'}; your molecule must be in SMILES format. [/INST]CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1cc(N2CCOCC2)cc(C(=O)NCC2CC2)n1,CN(CCc1ccccc1)c1cc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1cc(C(=O)NCC2CC2)nc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)nc(N2CCOCC2)n1,CN(CC1CC1)C(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1nc(C(=O)NC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(C(N)=O)cc(N2CCOCC2)n1,CNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CCNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CCCNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CCCCNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CCCCCCNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CC(C)CNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC(C)(C)C)cc(N2CCOCC2)n1,C#CCNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC(F)(F)F)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)O)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC(=O)O)cc(N2CCOCC2)n1,COC(=O)CNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CNC(=O)CNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCCO)cc(N2CCOCC2)n1,COCCNC(=O)c1cc(N2CCOCC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC#N)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCc2nccs2)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCc2ccccc2)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCc2ccc(-c3ccccc3)cc2)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(-c2ncc(C3CC3)[nH]2)cc(N2CCOCC2)n1,CN(CCc1ccccc1)c1nc(NC(=O)CC2CC2)cc(N2CCOCC2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(Cl)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)ncn1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(NCCc2ccccc2)n1,CN(Cc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(NCc2ccccc2)n1,CN(CCCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCCCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccc(Cl)cc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1cccc(Cl)c1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccccc1Cl)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,Cc1ccc(CCN(C)c2nc(C(=O)NCC3CC3)cc(N3CCOCC3)n2)cc1,Cc1ccccc1CCN(C)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,COc1ccc(CCN(C)c2nc(C(=O)NCC3CC3)cc(N3CCOCC3)n2)cc1,COc1ccccc1CCN(C)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccc(C(F)(F)F)cc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccc(Oc2ccccc2)cc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1cccc(Oc2ccccc2)c1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccccc1Oc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccccc1-c1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccncc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1cccnc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1ccccn1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CN(CCc1cccs1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CCN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,CC(C)N(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCOCC2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N(CCc2ccccc2)C2CC2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N(CCc2ccccc2)c2ccccc2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N(CCc2ccccc2)Cc2ccccc2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N(CCc2ccccc2)CCc2ccccc2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCc3ccccc3C2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCC(c3ccccc3)C2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCCC(c3ccccc3)C2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCCC2Cc2ccccc2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCCCC2Cc2ccccc2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCCCC2CC2CCCCC2)n1,COc1ccc(CC2CCCCN2c2nc(C(=O)NCC3CC3)cc(N3CCOCC3)n2)cc1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCOC(c3ccccc3)C2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCNC(c3ccccc3)C2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCN(Cc3ccccc3)C(c3ccccc3)C2)n1,O=C(NCC1CC1)c1cc(N2CCOCC2)nc(N2CCN(C(=O)OCc3ccccc3)C(c3ccccc3)C2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCCCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCCC(F)(F)C2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCC(F)(F)CC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCSCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCS(=O)(=O)CC2)n1,CN1CCN(c2cc(C(=O)NCC3CC3)nc(N(C)CCc3ccccc3)n2)CC1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCNCC2)n1,CC(=O)N1CCN(c2cc(C(=O)NCC3CC3)nc(N(C)CCc3ccccc3)n2)CC1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCN(C(=O)c3ccccc3)CC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCN(C(=O)OCc3ccccc3)CC2)n1,CN(C)c1cc(C(=O)NCC2CC2)nc(N(C)CCc2ccccc2)n1,CNc1cc(C(=O)NCC2CC2)nc(N(C)CCc2ccccc2)n1,CN(CCO)c1cc(C(=O)NCC2CC2)nc(N(C)CCc2ccccc2)n1,CCN(CC)c1cc(C(=O)NCC2CC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CC3(COC3)C2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCCC2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCC(F)(F)C2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCC(O)C2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CC[C@@H](O)C2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CC[C@H](O)C2)n1,COC1CCN(c2cc(C(=O)NCC3CC3)nc(N(C)CCc3ccccc3)n2)C1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCC(N(C)C)C2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(N2CCC(c3ccccc3)C2)n1,CN(Cc1ccccc1)c1cc(C(=O)NCC2CC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1cc(C(=O)NCC2CC2)nc(N(C)CCc2ccccc2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(-n2cccn2)n1,CN(CCc1ccccc1)c1nc(C(=O)NCC2CC2)cc(-n2ccnc2)n1,CN(CCc1ccccc1)c1nc(Oc2ccccc2)cc(C(=O)NCC2CC2)n1,CN(CCc1ccccc1)c1nc(Oc2cccnc2)cc(C(=O)NCC2CC2)n1,CN(C)c1cc(C(=O)NCC2CC2)nc(N2CCC[C@@H](c3ccccc3)C2)n1 |
[INST] Create new Unknown for target with these components: {'Q70EL2': 'MRVKDPTKALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHCNKKVLAQIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQKGGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQPDGPLYPLSAGKLLYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQPLNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q7L8S5': 'MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAGAAGGVLPRLL'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q8N6M0': 'MEAVLTEELDEEEQLLRRHRKEKKELQAKIQGMKNAVPKNDKKRRKQLTEDVAKLEKEMEQKHREELEQLKLTTKENKIDSVAVNISNLVLENQPPRISKAQKRREKKAALEKEREERIAEAEIENLTGARHMESEKLAQILAARQLEIKQIPSDGHCMYKAIEDQLKEKDCALTVVALRSQTAEYMQSHVEDFLPFLTNPNTGDMYTPEEFQKYCEDIVNTAAWGGQLELRALSHILQTPIEIIQADSPPIIVGEEYSKKPLILVYMRHAYGLGEHYNSVTRLVNIVTENCS'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q8R4K2': 'MNKPLTPSTYIRNLNVGILRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALLQTGKSPTCELLFDWGTTNCTVGDLVDLLVQIELFAPATLLLPDAVPQTVKSLPPREAATVAQTHGPCQEKDRTSVMPMPKLEHSCEPPDSSSPDNRSVESSDTRFHSFSFHELKSITNNFDEQPASAGGNRMGEGGFGVVYKGCVNNTIVAVKKLGAMVEISTEELKQQFDQEIKVMATCQHENLVELLGFSSDSDNLCLVYAYMPNGSLLDRLSCLDGTPPLSWHTRCKVAQGTANGIRFLHENHHIHRDIKSANILLDKDFTAKISDFGLARASARLAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLELITGLAAVDENREPQLLLDIKEEIEDEEKTIEDYTDEKMSDADPASVEAMYSAASQCLHEKKNRRPDIAKVQQLLQEMSA'}; your molecule must be in SMILES format. [/INST]CC(C)(O)[C@H](F)CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC1CC1 |
[INST] Create new Unknown for target with these components: {'Q8TAC2': 'MSQAPGAQPSPPTVYHERQRLELCAVHALNNVLQQQLFSQEAADEICKRLAPDSRLNPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLALPQVLGLILNLPSPVSLGLLSLPLRRRHWVALRQVDGVYYNLDSKLRAPEALGDEDGVRAFLAAALAQGLCEVLLVVTKEVEEKGSWLRTD'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q96DC9': 'MSETSFNLISEKCDILSILRDHPENRIYRRKIEELSKRFTAIRKTKGDGNCFYRALGYSYLESLLGKSREIFKFKERVLQTPNDLLAAGFEEHKFRNFFNAFYSVVELVEKDGSVSSLLKVFNDQSASDHIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMATECDHIQITALSQALSIALQVEYVDEMDTALNHHVFPEAATPSVYLLYKTSHYNILYAADKH'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q96FJ0': 'MDQPFTVNSLKKLAAMPDHTDVSLSPEERVRALSKLGCNITISEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKNDLLKKYNVEYQEYLQSKNKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMRSQQTSGLSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYASHSPPVNRALTPAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGKLTHNEFTITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVLVKDIKIIVLDLR'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q96JH7': 'MSQPPPPPPPLPPPPPPPEAPQTPSSLASAAASGGLLKRRDRRILSGSCPDPKCQARLFFPASGSVSIECTECGQRHEQQQLLGVEEVTDPDVVLHNLLRNALLGVTGAPKKNTELVKVMGLSNYHCKLLSPILARYGMDKQTGRAKLLRDMNQGELFDCALLGDRAFLIEPEHVNTVGYGKDRSGSLLYLHDTLEDIKRANKSQECLIPVHVDGDGHCLVHAVSRALVGRELFWHALRENLKQHFQQHLARYQALFHDFIDAAEWEDIINECDPLFVPPEGVPLGLRNIHIFGLANVLHRPIILLDSLSGMRSSGDYSATFLPGLIPAEKCTGKDGHLNKPICIAWSSSGRNHYIPLVGIKGAALPKLPMNLLPKAWGVPQDLIKKYIKLEEDGGCVIGGDRSLQDKYLLRLVAAMEEVFMDKHGIHPSLVADVHQYFYRRTGVIGVQPEEVTAAAKKAVMDNRLHKCLLCGALSELHVPPEWLAPGGKLYNLAKSTHGQLRTDKNYSFPLNNLVCSYDSVKDVLVPDYGMSNLTACNWCHGTSVRKVRGDGSIVYLDGDRTNSRSTGGKCGCGFKHFWDGKEYDNLPEAFPITLEWGGRVVRETVYWFQYESDSSLNSNVYDVAMKLVTKHFPGEFGSEILVQKVVHTILHQTAKKNPDDYTPVNIDGAHAQRVGDVQGQESESQLPTKIILTGQKTKTLHKEELNMSKTERTIQQNITEQASVMQKRKTEKLKQEQKGQPRTVSPSTIRDGPSSAPATPTKAPYSPTTSKEKKIRITTNDGRQSMVTLKSSTTFFELQESIAREFNIPPYLQCIRYGFPPKELMPPQAGMEKEPVPLQHGDRITIEILKSKAEGGQSAAAHSAHTVKQEDIAVTGKLSSKELQEQAEKEMYSLCLLATLMGEDVWSYAKGLPHMFQQGGVFYSIMKKTMGMADGKHCTFPHLPGKTFVYNASEDRLELCVDAAGHFPIGPDVEDLVKEAVSQVRAEATTRSRESSPSHGLLKLGSGGVVKKKSEQLHNVTAFQGKGHSLGTASGNPHLDPRARETSVVRKHNTGTDFSNSSTKTEPSVFTASSSNSELIRIAPGVVTMRDGRQLDPDLVEAQRKKLQEMVSSIQASMDRHLRDQSTEQSPSDLPQRKTEVVSSSAKSGSLQTGLPESFPLTGGTENLNTETTDGCVADALGAAFATRSKAQRGNSVEELEEMDSQDAEMTNTTEPMDHS'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q96KN8': 'MGLSPGAEGEYALRLPRIPPPLPKPASRTASTGPKDQPPALRRSAVPHSGLNSISPLELEESVGFAALVQLPAKQPPPGTLEQGRSIQQGEKAVVSLETTPSQKADWSSIPKPENEGKLIKQAAEGKPRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVGSITSIFSNRAVVKYSRLEDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVPRSQQVEHALMEGAKAAGAVISAVVDSIKPKPITA'}; your molecule must be in SMILES format. [/INST]O=C(CCc1ccc(Cl)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)NCCCCc1ccccc1,O=C(NCc1ccccc1)C(F)(F)C(O)CCc1ccccc1,CCOC(=O)C(F)(F)C(O)CCc1ccccc1,O=C(CCc1ccccc1)C(F)(F)C(=O)NCc1ccccc1,O=C(CCc1ccccc1)C(F)(F)C(=O)NCCc1ccccc1,O=C(CCc1ccccc1)[C@H](F)C(=O)NCc1ccccc1,O=C(CCc1ccccc1)CC(=O)NCc1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)NCc1ccccc1,CCNC(=O)C(=O)CCc1ccc(Cl)cc1,O=C(NCCc1ccccc1)C(=O)c1ccc(Cl)cc1,CN(CCc1ccccc1)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCCC1,CN(C)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCOCC1,CN1CCN(C(=O)C(=O)CCc2ccc(Cl)cc2)CC1,COCCN(CCOC)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CC[C@@H](c2ccccc2)C1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCC1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCC[C@H]1c1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCC[C@H]1Cc1ccccc1,CCN(CCc1ccccc1)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(NCCc1ccccc1)C(O)CCc1ccc(Cl)cc1,O=C(CCc1ccccc1)C(=O)NCCc1ccccc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccccc1,O=C(CCCCc1ccccc1)C(=O)NCCc1ccccc1,O=C(NCCc1ccccc1)C(=O)c1ccccc1,CC(=O)C(=O)NCCc1ccccc1,Cc1ccc(CCC(=O)C(=O)NCCc2ccccc2)cc1,O=C(CCc1ccc(C(F)(F)F)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(F)cc1)C(=O)NCCc1ccccc1,COc1ccc(CCC(=O)C(=O)NCCc2ccccc2)cc1,O=C(CCc1ccc(Oc2ccccc2)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccccc1Cl)C(=O)NCCc1ccccc1,O=C(CCc1cccc(Cl)c1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(Cl)c(Cl)c1)C(=O)NCCc1ccccc1,O=C(/C=C/c1ccc(Cl)cc1)C(=O)NCCc1ccccc1,O=C(/C=C/c1ccccc1)C(=O)NCCc1ccccc1,COc1ccc(/C=C/C(=O)C(=O)NCCc2ccccc2)cc1,O=C(/C=C/c1ccc(Br)cc1)C(=O)NCCc1ccccc1,O=C(/C=C/c1cccc(Br)c1)C(=O)NCCc1ccccc1,O=C(/C=C/c1cccc(-c2ccccc2)c1)C(=O)NCCc1ccccc1,Cc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1,COc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1,COc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1OC,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(O)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Br)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1cccc(Cl)c1,O=C(CCCc1ccccc1)C(=O)NCCc1ccccc1Cl,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Cl)cc1Cl,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccccc2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2cnccn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ncccn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccc(C(F)(F)F)nc2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccnc(Cl)n2)cc1 |
[INST] Create new Unknown for target with these components: {'Q9EQ16': 'MDDGHQESALYDGHYEGDFWLFNNSSDNSQENKRFLKFKEVFLPCVYLVVFVFGLLGNSLVLIIYIFYQKLRTLTDVFLLNLPLADLVFVCTLPFWAYAGTYEWVFGTVMCKTLRGMYTMNFYVSMLTLTCITVDRFIVVVQATKAFNRQAKWKIWGQVICLLIWVVSLLVSLPQIIYGHVQDIDKLICQYHSEEISTMVLVIQMTLGFFLPLLTMILCYSGIIKTLLHARNFQKHKSLKIIFLVVAVFLLTQTPFNLAMLIQSTSWEYYTITSFKYAIVVTEAIAYFRACLNPVLYAFVGLKFRKNVWKLMKDIGCLSHLGVSSQWKSSEDSSKTCSASHNVETTSMFQL'}; your molecule must be in SMILES format. [/INST]COc1cc(C(=O)N[C@@H]2C[C@H]3CCC[C@@H](C2)N3CC(=O)Nc2ccccc2Cl)cc(OC)c1OC,COc1cc(C(=O)N[C@@H]2C[C@H]3CCC[C@@H](C2)N3Cc2nc3c(C(F)(F)F)cccc3s2)cc(OC)c1OC |
[INST] Create new Unknown for target with these components: {'Q9GZZ1': 'MKGSRIELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLEVGELAKLAYFNDIAVGAVCCRVDHSQNQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEPADAHVLQKNLKVPSGQNADVQKTDN'}; your molecule must be in SMILES format. [/INST]CSCC[C@H](NC(=O)CSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O,CSCC[C@H](NC(=O)CSCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O,CNC(=O)[C@H](CC1CCN(C(=O)c2cc(C(C)(C)C)nn2C)CC1)NC(=O)C1CCCC(=O)N1,CNC(=O)c1csc(C2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-c3nn[nH]n3)cc2)n1,CNC(=O)[C@H](CC1CCN(C(=O)c2cc(C(C)(C)C)nn2C)CC1)NC(=O)[C@@H]1CCCC(=O)N1,CNC(=O)[C@H](CC1CCN(C(=O)c2cc(C(C)(C)C)nn2C)CC1)NC(=O)[C@H]1CCCC(=O)N1,CNC(=O)c1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-c3nn[nH]n3)cc2)n1,CNC(=O)c1csc([C@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-c3nn[nH]n3)cc2)n1,CNC(=O)c1coc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-c3nn[nH]n3)cc2)n1,CNC(=O)c1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(C)=O)n1,CNC(=O)c1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2Cc2ccc(-c3nn[nH]n3)cc2)n1,CNC(=O)c1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2cccc(-c3nn[nH]n3)c2)n1,Cc1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-c3nn[nH]n3)cc2)n1,Cc1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccccc2)n1,Cc1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-c3nnc[nH]3)cc2)n1,Cc1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-n3ccnn3)cc2)n1,Cc1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(-n3ncnn3)cc2)n1,Cc1csc([C@@H]2C[C@H](NC(=O)[C@@H]3CC(=O)N(C)C(=O)N3)CN2C(=O)c2ccc(C(=O)O)cc2)n1 |
[INST] Create new Unknown for target with these components: {'Q9H3M9': 'MDFIFHEKQEGFLCAQHCLNNLLQGEYFSPVELASIAHQLDEEERMRMAEGGVTSEEYLAFLQQPSENMDDTGFFSIQVISNALKFWGLEIIHFNNPEYQKLGIDPINERSFICNYKQHWFTIRKFGKHWFNLNSLLAGPELISDTCLANFLARLQQQAYSVFVVKGDLPDCEADQLLQIISVEEMDTPKLNGKKLVKQKEHRVYKTVLEKVSEESDESGTSDQDEEDFQRALELSRQETNREDEHLRSTIELSMQGSSGNTSQDLPKTSCVTPASEQPKKIKEDYFEKHQQEQKQQQQQSDLPGHSSYLHERPTTSSRAIESDLSDDISEGTVQAAVDTILEIMRKNLKIKGEK'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new None for target with these components: {'Q9NPP4': 'MNFIKDNSRALIQRMGMTVIKQITDDLFVWNVLNREEVNIICCEKVEQDAARGIIHMILKKGSESCNLFLKSLKEWNYPLFQDLNGQSLFHQTSEGDLDDLAQDLKDLYHTPSFLNFYPLGEDIDIIFNLKSTFTEPVLWRKDQHHHRVEQLTLNGLLQALQSPCIIEGESGKGKSTLLQRIAMLWGSGKCKALTKFKFVFFLRLSRAQGGLFETLCDQLLDIPGTIRKQTFMAMLLKLRQRVLFLLDGYNEFKPQNCPEIEALIKENHRFKNMVIVTTTTECLRHIRQFGALTAEVGDMTEDSAQALIREVLIKELAEGLLLQIQKSRCLRNLMKTPLFVVITCAIQMGESEFHSHTQTTLFHTFYDLLIQKNKHKHKGVAASDFIRSLDHCGDLALEGVFSHKFDFELQDVSSVNEDVLLTTGLLCKYTAQRFKPKYKFFHKSFQEYTAGRRLSSLLTSHEPEEVTKGNGYLQKMVSISDITSTYSSLLRYTCGSSVEATRAVMKHLAAVYQHGCLLGLSIAKRPLWRQESLQSVKNTTEQEILKAININSFVECGIHLYQESTSKSALSQEFEAFFQGKSLYINSGNIPDYLFDFFEHLPNCASALDFIKLDFYGGAMASWEKAAEDTGGIHMEEAPETYIPSRAVSLFFNWKQEFRTLEVTLRDFSKLNKQDIRYLGKIFSSATSLRLQIKRCAGVAGSLSLVLSTCKNIYSLMVEASPLTIEDERHITSVTNLKTLSIHDLQNQRLPGGLTDSLGNLKNLTKLIMDNIKMNEEDAIKLAEGLKNLKKMCLFHLTHLSDIGEGMDYIVKSLSSEPCDLEEIQLVSCCLSANAVKILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDRMNVLEQLTALMLPWGCDVQGSLSSLLKHLEEVPQLVKLGLKNWRLTDTEIRILGAFFGKNPLKNFQQLNLAGNRVSSDGWLAFMGVFENLKQLVFFDFSTKEFLPDPALVRKLSQVLSKLTFLQEARLVGWQFDDDDLSVITGAFKLVTA'}; your molecule must be in SMILES format. [/INST]CN[C@@H]1COc2c(S(=O)(=O)NC(=O)Nc3c4c(cc5c3CCC5)CCC4)cnn2C1 |
[INST] Create new Unknown for target with these components: {'Q9NQC7': 'MSSGLWSQEKVTSPYWEERIFYLLLQECSVTDKQTQKLLKVPKGSIGQYIQDRSVGHSRIPSAKGKKNQIGLKILEQPHAVLFVDEKDVVEINEKFTELLLAITNCEERFSLFKNRNRLSKGLQIDVGCPVKVQLRSGEEKFPGVVRFRGPLLAERTVSGIFFGVELLEEGRGQGFTDGVYQGKQLFQCDEDCGVFVALDKLELIEDDDTALESDYAGPGDTMQVELPPLEINSRVSLKVGETIESGTVIFCDVLPGKESLGYFVGVDMDNPIGNWDGRFDGVQLCSFACVESTILLHINDIIPALSESVTQERRPPKLAFMSRGVGDKGSSSHNKPKATGSTSDPGNRNRSELFYTLNGSSVDSQPQSKSKNTWYIDEVAEDPAKSLTEISTDFDRSSPPLQPPPVNSLTTENRFHSLPFSLTKMPNTNGSIGHSPLSLSAQSVMEELNTAPVQESPPLAMPPGNSHGLEVGSLAEVKENPPFYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFASLQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRPKEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYGKDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLYK'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q9NRA2': 'MRSPVRDLARNDGEESTDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSSQKSVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLTPDNTVGEWQTVFYIAAAINVFGAIFFTLFAKGEVQNWALNDHHGHRH'}; your molecule must be in SMILES format. [/INST]O=C(N[C@@H](CSCc1cc(=O)oc2cc(O)ccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21 |
[INST] Create new Unknown for target with these components: {'Q9NRA2': 'MRSPVRDLARNDGEESTDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLEDNRTSKACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLGFGILGTAVLTLFTPIAADLGVGPLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISYAGAQLGTVISLPLSGIICYYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYILSSLRNQLSSQKSVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSSLPYLGSWLCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLTPDNTVGEWQTVFYIAAAINVFGAIFFTLFAKGEVQNWALNDHHGHRH'}; your molecule must be in SMILES format. [/INST]O=C(N[C@@H](CSCc1cc(=O)oc2cc(O)ccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21,CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O |
[INST] Create new Unknown for target with these components: {'Q9NWW9': 'MALARPRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ'}; your molecule must be in SMILES format. [/INST]O=C(CCc1ccc(Cl)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)NCCCCc1ccccc1,O=C(NCc1ccccc1)C(F)(F)C(O)CCc1ccccc1,CCOC(=O)C(F)(F)C(O)CCc1ccccc1,O=C(CCc1ccccc1)C(F)(F)C(=O)NCc1ccccc1,O=C(CCc1ccccc1)C(F)(F)C(=O)NCCc1ccccc1,O=C(CCc1ccccc1)[C@H](F)C(=O)NCc1ccccc1,O=C(CCc1ccccc1)CC(=O)NCc1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)NCc1ccccc1,CCNC(=O)C(=O)CCc1ccc(Cl)cc1,O=C(NCCc1ccccc1)C(=O)c1ccc(Cl)cc1,CN(CCc1ccccc1)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCCC1,CN(C)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCOCC1,CN1CCN(C(=O)C(=O)CCc2ccc(Cl)cc2)CC1,COCCN(CCOC)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CC[C@@H](c2ccccc2)C1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCC1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCC[C@H]1c1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCC[C@H]1Cc1ccccc1,CCN(CCc1ccccc1)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(NCCc1ccccc1)C(O)CCc1ccc(Cl)cc1,O=C(CCc1ccccc1)C(=O)NCCc1ccccc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccccc1,O=C(CCCCc1ccccc1)C(=O)NCCc1ccccc1,O=C(NCCc1ccccc1)C(=O)c1ccccc1,CC(=O)C(=O)NCCc1ccccc1,Cc1ccc(CCC(=O)C(=O)NCCc2ccccc2)cc1,O=C(CCc1ccc(C(F)(F)F)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(F)cc1)C(=O)NCCc1ccccc1,COc1ccc(CCC(=O)C(=O)NCCc2ccccc2)cc1,O=C(CCc1ccc(Oc2ccccc2)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccccc1Cl)C(=O)NCCc1ccccc1,O=C(CCc1cccc(Cl)c1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(Cl)c(Cl)c1)C(=O)NCCc1ccccc1,O=C(/C=C/c1ccc(Cl)cc1)C(=O)NCCc1ccccc1,O=C(/C=C/c1ccccc1)C(=O)NCCc1ccccc1,COc1ccc(/C=C/C(=O)C(=O)NCCc2ccccc2)cc1,O=C(/C=C/c1ccc(Br)cc1)C(=O)NCCc1ccccc1,O=C(/C=C/c1cccc(Br)c1)C(=O)NCCc1ccccc1,O=C(/C=C/c1cccc(-c2ccccc2)c1)C(=O)NCCc1ccccc1,Cc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1,COc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1,COc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1OC,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(O)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Br)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1cccc(Cl)c1,O=C(CCCc1ccccc1)C(=O)NCCc1ccccc1Cl,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Cl)cc1Cl,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccccc2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2cnccn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ncccn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccc(C(F)(F)F)nc2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccnc(Cl)n2)cc1 |
[INST] Create new Unknown for target with these components: {'Q9P275': 'MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQKIEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDPPARRQGSEHTYESCGDGVPAPQKVLFPTERLSLRWERVFRVGAGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFLNIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKVVLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRPSVIPDHSKKNIGNGIISSPLTGKRQDSGTMKKPHTTEEIGVPISRNGSTLGLKSQNGCIPPKLPSGSPSPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSPRTAQGLPGTSNSNSSRSGSQRQGSWDSRDVVLSTSPKLLATATANGHGLKGNDESAGLDRRGSSSSSPEHSASSDSTKAPQTPRSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSNTTTEPASTMSPPPAKKLALSAKKASTLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVASTWPVHRARAVSPAPQSSSRLQPPFSPHPTLLSSTPKPPGTSEPRSCSSISTALPQVNEDLVSLPHQLPEASEPPQSPSEKRKKTFVGEPQRLGSETRLPQHIREATAAPHGKRKRKKKKRPEDTAASALQEGQTQRQPGSPMYRREGQAQLPAVRRQEDGTQPQVNGQQVGCVTDGHHASSRKRRRKGAEGLGEEGGLHQDPLRHSCSPMGDGDPEAMEESPRKKKKKKRKQETQRAVEEDGHLKCPRSAKPQDAVVPESSSCAPSANGWCPGDRMGLSQAPPVSWNGERESDVVQELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRQARTETVVDDWDEEFDRGKEKKIKKFKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q9P275': 'MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQKIEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDPPARRQGSEHTYESCGDGVPAPQKVLFPTERLSLRWERVFRVGAGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFLNIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKVVLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRPSVIPDHSKKNIGNGIISSPLTGKRQDSGTMKKPHTTEEIGVPISRNGSTLGLKSQNGCIPPKLPSGSPSPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSPRTAQGLPGTSNSNSSRSGSQRQGSWDSRDVVLSTSPKLLATATANGHGLKGNDESAGLDRRGSSSSSPEHSASSDSTKAPQTPRSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSNTTTEPASTMSPPPAKKLALSAKKASTLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVASTWPVHRARAVSPAPQSSSRLQPPFSPHPTLLSSTPKPPGTSEPRSCSSISTALPQVNEDLVSLPHQLPEASEPPQSPSEKRKKTFVGEPQRLGSETRLPQHIREATAAPHGKRKRKKKKRPEDTAASALQEGQTQRQPGSPMYRREGQAQLPAVRRQEDGTQPQVNGQQVGCVTDGHHASSRKRRRKGAEGLGEEGGLHQDPLRHSCSPMGDGDPEAMEESPRKKKKKKRKQETQRAVEEDGHLKCPRSAKPQDAVVPESSSCAPSANGWCPGDRMGLSQAPPVSWNGERESDVVQELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRQARTETVVDDWDEEFDRGKEKKIKKFKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C,O=C1c2ccccc2C(=O)c2oc(-c3cccnc3)nc21,CN1CC[C@@H](Oc2ccc(Cl)c(-c3nc4c(o3)C(=O)c3ccccc3C4=O)c2)C1,CN1CC[C@@H](Oc2ccc(Cl)c(-c3nc4c(o3)C(=O)c3ccccc3C4=O)c2F)C1,CN1CC[C@@H](Oc2ccc(F)c(-c3nc4c(o3)C(=O)c3ccccc3C4=O)c2Cl)C1 |
[INST] Create new Unknown for target with these components: {'Q9P2H5': 'MDKILEAVVTSSYPVSVKQGLVRRVLEAARQPLEREQCLALLALGARLYVGGAEELPRRVGCQLLHVAGRHHPDVFAEFFSARRVLRLLQGGAGPPGPRALACVQLGLQLLPEGPAADEVFALLRREVLRTVCERPGPAACAQVARLLARHPRCVPDGPHRLLFCQQLVRCLGRFRCPAEGEEGAVEFLEQAQQVSGLLAQLWRAQPAAILPCLKELFAVISCAEEEPPSSALASVVQHLPLELMDGVVRNLSNDDSVTDSQMLTAISRMIDWVSWPLGKNIDKWIIALLKGLAAVKKFSILIEVSLTKIEKVFSKLLYPIVRGAALSVLKYMLLTFQHSHEAFHLLLPHIPPMVASLVKEDSNSGTSCLEQLAELVHCMVFRFPGFPDLYEPVMEAIKDLHVPNEDRIKQLLGQDAWTSQKSELAGFYPRLMAKSDTGKIGLINLGNTCYVNSILQALFMASDFRHCVLRLTENNSQPLMTKLQWLFGFLEHSQRPAISPENFLSASWTPWFSPGTQQDCSEYLKYLLDRLHEEEKTGTRICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPERCRRRRLGSVMRPTEDITARELPPPTSAQGPGRVGPRRQRKHCITEDTPPTSLYIEGLDSKEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETEKEAEQEKEEDSLGAGTHPDAAIPSGERTCGSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGGRGQAYDLCSVVVHSGVSSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQRPREGPEAELGSSRVRTEPTLHKDLMEAISKDNILYLQEQEKEARSRAAYISALPTSPHWGRGFDEDKDEDEGSPGGCNPAGGNGGDFHRLVF'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q9UL19': 'MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEVKRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQLRYGKSRCKQVEKAKVEVGVATALGILVVAGCSFAIRRYQKKATA'}; your molecule must be in SMILES format. [/INST]O=C(CCc1ccc(Cl)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)NCCCCc1ccccc1,O=C(NCc1ccccc1)C(F)(F)C(O)CCc1ccccc1,CCOC(=O)C(F)(F)C(O)CCc1ccccc1,O=C(CCc1ccccc1)C(F)(F)C(=O)NCc1ccccc1,O=C(CCc1ccccc1)C(F)(F)C(=O)NCCc1ccccc1,O=C(CCc1ccccc1)[C@H](F)C(=O)NCc1ccccc1,O=C(CCc1ccccc1)CC(=O)NCc1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)NCc1ccccc1,CCNC(=O)C(=O)CCc1ccc(Cl)cc1,O=C(NCCc1ccccc1)C(=O)c1ccc(Cl)cc1,CN(CCc1ccccc1)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCCC1,CN(C)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCOCC1,CN1CCN(C(=O)C(=O)CCc2ccc(Cl)cc2)CC1,COCCN(CCOC)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CC[C@@H](c2ccccc2)C1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCC1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCCC[C@H]1c1ccccc1,O=C(CCc1ccc(Cl)cc1)C(=O)N1CCC[C@H]1Cc1ccccc1,CCN(CCc1ccccc1)C(=O)C(=O)CCc1ccc(Cl)cc1,O=C(NCCc1ccccc1)C(O)CCc1ccc(Cl)cc1,O=C(CCc1ccccc1)C(=O)NCCc1ccccc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccccc1,O=C(CCCCc1ccccc1)C(=O)NCCc1ccccc1,O=C(NCCc1ccccc1)C(=O)c1ccccc1,CC(=O)C(=O)NCCc1ccccc1,Cc1ccc(CCC(=O)C(=O)NCCc2ccccc2)cc1,O=C(CCc1ccc(C(F)(F)F)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(F)cc1)C(=O)NCCc1ccccc1,COc1ccc(CCC(=O)C(=O)NCCc2ccccc2)cc1,O=C(CCc1ccc(Oc2ccccc2)cc1)C(=O)NCCc1ccccc1,O=C(CCc1ccccc1Cl)C(=O)NCCc1ccccc1,O=C(CCc1cccc(Cl)c1)C(=O)NCCc1ccccc1,O=C(CCc1ccc(Cl)c(Cl)c1)C(=O)NCCc1ccccc1,O=C(/C=C/c1ccc(Cl)cc1)C(=O)NCCc1ccccc1,O=C(/C=C/c1ccccc1)C(=O)NCCc1ccccc1,COc1ccc(/C=C/C(=O)C(=O)NCCc2ccccc2)cc1,O=C(/C=C/c1ccc(Br)cc1)C(=O)NCCc1ccccc1,O=C(/C=C/c1cccc(Br)c1)C(=O)NCCc1ccccc1,O=C(/C=C/c1cccc(-c2ccccc2)c1)C(=O)NCCc1ccccc1,Cc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1,COc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1,COc1ccc(CCNC(=O)C(=O)CCCc2ccccc2)cc1OC,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(O)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Br)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1cccc(Cl)c1,O=C(CCCc1ccccc1)C(=O)NCCc1ccccc1Cl,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Cl)cc1Cl,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccccc2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2cnccn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ncccn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccc(C(F)(F)F)nc2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1,O=C(CCCc1ccccc1)C(=O)NCCc1ccc(Oc2ccnc(Cl)n2)cc1 |
[INST] Create new Unknown for target with these components: {'Q9Y5T5': 'MGKKRTKGKTVPIDDSSETLEPVCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDKAEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEVQYCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDKNLKKTVEDEDQDSEEEKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPEDSEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMKNINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHLSNLVLHGDIPQDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL'}; your molecule must be in SMILES format. [/INST]Cc1cc(Cl)cc(-c2ccnc3cc(CN4C(=O)C5C(C4=O)C5(C)C)sc23)c1O[C@@H]1CCNC[C@@H]1C |
[INST] Create new Unknown for target with these components: {'Q46085': 'MKRKCLSKRLMLAITMATIFTVNSTLPIYAAVDKNNATAAVQNESKRYTVSYLKTLNYYDLVDLLVKTEIENLPDLFQYSSDAKEFYGNKTRMSFIMDEIGRRAPQYTEIDHKGIPTLVEVVRAGFYLGFHNKELNEINKRSFKERVIPSILAIQKNPNFKLGTEVQDKIVSATGLLAGNETAPPEVVNNFTPILQDCIKNIDRYALDDLKSKALFNVLAAPTYDITEYLRATKEKPENTPWYGKIDGFINELKKLALYGKINDNNSWIIDNGIYHIAPLGKLHSNNKIGIETLTEVMKVYPYLSMQHLQSADQIKRHYDSKDAEGNKIPLDKFKKEGKEKYCPKTYTFDDGKVIIKAGARVEEEKVKRLYWASKEVNSQFFRVYGIDKPLEEGNPDDILTMVIYNSPEEYKLNSVLYGYDTNNGGMYIEPEGTFFTYEREAQESTYTLEELFRHEYTHYLQGRYAVPGQWGRTKLYDNDRLTWYEEGGAELFAGSTRTSGILPRKSIVSNIHNTTRNNRYKLSDTVHSKYGASFEFYNYACMFMDYMYNKDMGILNKLNDLAKNNDVDGYDNYIRDLSSNYALNDKYQDHMQERIDNYENLTVPFVADDYLVRHAYKNPNEIYSEISEVAKLKDAKSEVKKSQYFSTFTLRGSYTGGASKGKLEDQKAMNKFIDDSLKKLDTYSWSGYKTLTAYFTNYKVDSSNRVTYDVVFHGYLPNEGDSKNSLPYGKINGTYKGTEKEKIKFSSEGSFDPDGKIVSYEWDFGDGNKSNEENPEHSYDKVGTYTVKLKVTDDKGESSVSTTTAEIKDLSENKLPVIYMHVPKSGALNQKVVFYGKGTYDPDGSIAGYQWDFGDGSDFSSEQNPSHVYTKKGEYTVTLRVMDSSGQMSEKTMKIKITDPVYPIGTEKEPNNSKETASGPIVPGIPVSGTIENTSDQDYFYFDVITPGEVKIDINKLGYGGATWVVYDENNNAVSYATDDGQNLSGKFKADKPGRYYIHLYMFNGSYMPYRINIEGSVGR'}; your molecule must be in SMILES format. [/INST]CC(=O)c1ccc(NC(=O)CS)cc1,COc1ccc(N2C(=O)CC(S)C2=O)cc1,CC(=O)c1ccc(N2C(=O)CC(S)C2=O)cc1,CC(=O)c1ccc(NC(=O)CS)cc1 |
[INST] Create new Unknown for target with these components: {'Q46085': 'MKRKCLSKRLMLAITMATIFTVNSTLPIYAAVDKNNATAAVQNESKRYTVSYLKTLNYYDLVDLLVKTEIENLPDLFQYSSDAKEFYGNKTRMSFIMDEIGRRAPQYTEIDHKGIPTLVEVVRAGFYLGFHNKELNEINKRSFKERVIPSILAIQKNPNFKLGTEVQDKIVSATGLLAGNETAPPEVVNNFTPILQDCIKNIDRYALDDLKSKALFNVLAAPTYDITEYLRATKEKPENTPWYGKIDGFINELKKLALYGKINDNNSWIIDNGIYHIAPLGKLHSNNKIGIETLTEVMKVYPYLSMQHLQSADQIKRHYDSKDAEGNKIPLDKFKKEGKEKYCPKTYTFDDGKVIIKAGARVEEEKVKRLYWASKEVNSQFFRVYGIDKPLEEGNPDDILTMVIYNSPEEYKLNSVLYGYDTNNGGMYIEPEGTFFTYEREAQESTYTLEELFRHEYTHYLQGRYAVPGQWGRTKLYDNDRLTWYEEGGAELFAGSTRTSGILPRKSIVSNIHNTTRNNRYKLSDTVHSKYGASFEFYNYACMFMDYMYNKDMGILNKLNDLAKNNDVDGYDNYIRDLSSNYALNDKYQDHMQERIDNYENLTVPFVADDYLVRHAYKNPNEIYSEISEVAKLKDAKSEVKKSQYFSTFTLRGSYTGGASKGKLEDQKAMNKFIDDSLKKLDTYSWSGYKTLTAYFTNYKVDSSNRVTYDVVFHGYLPNEGDSKNSLPYGKINGTYKGTEKEKIKFSSEGSFDPDGKIVSYEWDFGDGNKSNEENPEHSYDKVGTYTVKLKVTDDKGESSVSTTTAEIKDLSENKLPVIYMHVPKSGALNQKVVFYGKGTYDPDGSIAGYQWDFGDGSDFSSEQNPSHVYTKKGEYTVTLRVMDSSGQMSEKTMKIKITDPVYPIGTEKEPNNSKETASGPIVPGIPVSGTIENTSDQDYFYFDVITPGEVKIDINKLGYGGATWVVYDENNNAVSYATDDGQNLSGKFKADKPGRYYIHLYMFNGSYMPYRINIEGSVGR'}; your molecule must be in SMILES format. [/INST]CC(=O)c1ccc(NC(=O)CS)cc1,COc1ccc(N2C(=O)CC(S)C2=O)cc1,CC(=O)c1ccc(N2C(=O)CC(S)C2=O)cc1,CC(=O)c1ccc(NC(=O)CS)cc1,COc1cc2ccc(=O)oc2cc1OC |
[INST] Create new Unknown for target with these components: {'Q46085': 'MKRKCLSKRLMLAITMATIFTVNSTLPIYAAVDKNNATAAVQNESKRYTVSYLKTLNYYDLVDLLVKTEIENLPDLFQYSSDAKEFYGNKTRMSFIMDEIGRRAPQYTEIDHKGIPTLVEVVRAGFYLGFHNKELNEINKRSFKERVIPSILAIQKNPNFKLGTEVQDKIVSATGLLAGNETAPPEVVNNFTPILQDCIKNIDRYALDDLKSKALFNVLAAPTYDITEYLRATKEKPENTPWYGKIDGFINELKKLALYGKINDNNSWIIDNGIYHIAPLGKLHSNNKIGIETLTEVMKVYPYLSMQHLQSADQIKRHYDSKDAEGNKIPLDKFKKEGKEKYCPKTYTFDDGKVIIKAGARVEEEKVKRLYWASKEVNSQFFRVYGIDKPLEEGNPDDILTMVIYNSPEEYKLNSVLYGYDTNNGGMYIEPEGTFFTYEREAQESTYTLEELFRHEYTHYLQGRYAVPGQWGRTKLYDNDRLTWYEEGGAELFAGSTRTSGILPRKSIVSNIHNTTRNNRYKLSDTVHSKYGASFEFYNYACMFMDYMYNKDMGILNKLNDLAKNNDVDGYDNYIRDLSSNYALNDKYQDHMQERIDNYENLTVPFVADDYLVRHAYKNPNEIYSEISEVAKLKDAKSEVKKSQYFSTFTLRGSYTGGASKGKLEDQKAMNKFIDDSLKKLDTYSWSGYKTLTAYFTNYKVDSSNRVTYDVVFHGYLPNEGDSKNSLPYGKINGTYKGTEKEKIKFSSEGSFDPDGKIVSYEWDFGDGNKSNEENPEHSYDKVGTYTVKLKVTDDKGESSVSTTTAEIKDLSENKLPVIYMHVPKSGALNQKVVFYGKGTYDPDGSIAGYQWDFGDGSDFSSEQNPSHVYTKKGEYTVTLRVMDSSGQMSEKTMKIKITDPVYPIGTEKEPNNSKETASGPIVPGIPVSGTIENTSDQDYFYFDVITPGEVKIDINKLGYGGATWVVYDENNNAVSYATDDGQNLSGKFKADKPGRYYIHLYMFNGSYMPYRINIEGSVGR'}; your molecule must be in SMILES format. [/INST]CC(=O)c1ccc(NC(=O)CS)cc1,COc1ccc(N2C(=O)CC(S)C2=O)cc1,CC(=O)c1ccc(N2C(=O)CC(S)C2=O)cc1,CC(=O)c1ccc(NC(=O)CS)cc1,COc1cc2ccc(=O)oc2cc1OC,O=C(O)CN(CC1c2ccccc2C=Cc2ccccc21)C(=O)NS(=O)(=O)c1ccc(F)cc1,CC(=O)c1ccc(NC(=O)CSC(N)=O)cc1,CC(=O)c1ccc(NC(=O)CP(=O)([O-])[O-])cc1.[Na+].[Na+] |
[INST] Create new Unknown for target with these components: {'Q8TDQ0': 'MFSHLPFDCVLLLLLLLLTRSSEVEYRAEVGQNAYLPCFYTPAAPGNLVPVCWGKGACPVFECGNVVLRTDERDVNYWTSRYWLNGDFRKGDVSLTIENVTLADSGIYCCRIQIPGIMNDEKFNLKLVIKPAKVTPAPTRQRDFTAAFPRMLTTRGHGPAETQTLGSLPDINLTQISTLANELRDSRLANDLRDSGATIRIGIYIGAGICAGLALALIFGALIFKWYSHSKEKIQNLSLISLANLPPSGLANAVAEGIRSEENIYTIEENVYEVEEPNEYYCYVSSRQQPSQPLGCRFAMP'}; your molecule must be in SMILES format. [/INST]Cc1nc2c3cc(-c4ccncc4C)c(Cl)cc3[nH]c(=O)n2n1,Cc1nc2c3cc(-c4ccc(NS(C)(=O)=O)cc4Cl)c(Cl)cc3[nH]c(=O)n2n1 |
[INST] Create new None for target with these components: {'O95760': 'MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEVCPMYFMKLRSGLMIKKEACYFRRETTKRPSLKTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPITEYLASLSTYNDQSITFALEDESYEIYVEDLKKDEKKDKVLLSYYESQHPSNESGDGVDGKMLMVTLSPTKDFWLHANNKEHSVELHKCEKPLPDQAFFVLHNMHSNCVSFECKTDPGVFIGVKDNHLALIKVDSSENLCTENILFKLSET'}; your molecule must be in SMILES format. [/INST]COc1ccc([C@H]2CCCN2Cc2ccc(-c3ccccc3[N+](=O)[O-])o2)cc1,COc1ccc([C@@H]2CCCN2Cc2ccc(-c3ccccc3[N+](=O)[O-])o2)cc1 |
[INST] Create new Small molecule for target with these components: {}; your molecule must be in SMILES format. [/INST]NCCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCCN)cc1C2=O,NCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCN)cc1C2=O,NCCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCCN)cc1C2=O,NCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCN)cc1C2=O,NCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCN)cc1C2=O,C[C@H](NC(=O)C(N)CN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CN)cc1C2=O,NCCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCCN)cc1C2=O,NCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCN)cc1C2=O,NCCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCCN)cc1C2=O,NCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCN)cc1C2=O,NCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCN)cc1C2=O,C[C@H](NC(=O)C(N)CN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CN)cc1C2=O |
[INST] Create new Small molecule for target with these components: {}; your molecule must be in SMILES format. [/INST]NCCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCCN)cc1C2=O,NCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCN)cc1C2=O,NCCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCCN)cc1C2=O,NCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCN)cc1C2=O,NCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCN)cc1C2=O,C[C@H](NC(=O)C(N)CN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CN)cc1C2=O,NCCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCCN)cc1C2=O,NCCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCCN)cc1C2=O,NCCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCCN)cc1C2=O,NCCC(N)C(=O)NCCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CCNC(=O)C(N)CCN)cc1C2=O,NCCCC(N)C(=O)NCC(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)CNC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC(=O)C(N)CCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CCN)cc1C2=O,C[C@H](NC(=O)C(N)CN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC(=O)C(N)CN)cc1C2=O,C[C@@H](NC(=O)C(N)CCCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@@H](C)NC(=O)C(N)CCCCN)cc1C2=O,C[C@@H](NC(=O)C(N)CCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@@H](C)NC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC1(N)CCNCC1)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC3(N)CCNCC3)cc1C2=O,C[C@@H](NC1CCNCC1)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@@H](C)NC3CCNCC3)cc1C2=O,C[C@@H](NC(=O)C(N)CCCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@@H](C)NC(=O)C(N)CCCCN)cc1C2=O,C[C@@H](NC(=O)C(N)CCCN)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@@H](C)NC(=O)C(N)CCCN)cc1C2=O,C[C@H](NC1(N)CCNCC1)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@H](C)NC3(N)CCNCC3)cc1C2=O,C[C@@H](NC1CCNCC1)C(=O)Nc1ccc2c(c1)C(=O)c1ccc(NC(=O)[C@@H](C)NC3CCNCC3)cc1C2=O |
[INST] Create new Small molecule for target with these components: {'P9WFW3': 'MLRSHAAGLLREGDAGQQVTLAGWVARRRDHGGVIFIDLRDASGIAQVVFRDPQDTEVLAQAHRLRAEFCVSVAGVVEIRPEGNANPEIATGEIEVNATSLTVLGECAPLPFQLDEPAGEELRLKYRYLDLRRDDPAAAIRLRSRVNAAARAVLARHDFVEIETPTITRSTPEGARDFLVPARLHPGSFYALPQSPQLFKQLLMVAGMERYYQIARCYRDEDFRADRQPEFTQLDMEMSFVDAEDIIAISEEVLTELWALIGYRIPTPIPRIGYAEAMRRFGTDKPDLRFGLELVECTDFFSDTTFRVFQAPYVGAVVMPGGASQPRRTLDGWQDWAKQRGHRGLAYVLVAEDGTLGGPVAKNLTEAERTGLADHVGAKPGDCIFFSAGPVKSSRALLGAARVEIANRLGLIDPDAWAFVWVVDPPLFEPADEATAAGEVAVGSGAWTAVHHAFTAPKPEWEDRIESDTGSVLADAYDIVCNGHEIGGGSVRIHRRDIQERVFAVMGLDKAEAEEKFGFLLEAFMFGAPPHGGIAFGWDRTTALLAGMDSIREVIAFPKTGGGVDPLTDAPAPITAQQRKESGIDAQPKRVQQA'}; your molecule must be in SMILES format. [/INST]Cn1nc2c(cc1=O)CN(CC(=O)Nc1ccc(Cl)cn1)CC2,Cn1nc2c(cc1=O)CN(CC(=O)Nc1ccc(Cl)cn1)CC2,Cc1cc(CN2CCc3nn(C)c(=O)cc3C2)on1,Cc1cc(CN2CCc3nn(C)c(=O)cc3C2)on1,CNc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,COc1cccc(C2CC(=O)Nc3nc(N)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N)sc32)c1OC,CCC(C)CNc1ccc2oc(COC)nc2c1,CCC(C)CNc1ccc2oc(COC)nc2c1,COCc1nc2cc(NCc3ccncc3)ccc2o1,COCc1nc2cc(NCc3ccncc3)ccc2o1,COCCN(C)C(=O)Cn1cccc(OC)c1=O,COCCN(C)C(=O)Cn1cccc(OC)c1=O,CCCN(C(=O)c1ccccn1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1ccccn1)c1nc2c(s1)CCc1c-2cnn1C,Cn1cc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)ccc1=O,Cn1cc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)ccc1=O,Cc1ccc(-c2nc(CN3CCc4nn(C)c(=O)cc4C3)co2)cc1,Cc1ccc(-c2nc(CN3CCc4nn(C)c(=O)cc4C3)co2)cc1,Cn1nc2c(cc1=O)CN(Cc1coc(-c3cccs3)n1)CC2,Cn1nc2c(cc1=O)CN(Cc1coc(-c3cccs3)n1)CC2,Cn1cc(NC(=O)N2CCC(c3ccccc3)CC2)ccc1=O,Cn1cc(NC(=O)N2CCC(c3ccccc3)CC2)ccc1=O,Cn1cc(NC(=O)N2CCC(NS(C)(=O)=O)CC2)ccc1=O,Cn1cc(NC(=O)N2CCC(NS(C)(=O)=O)CC2)ccc1=O,Cn1cc(NC(=O)N2CCC(NS(C)(=O)=O)CC2)ccc1=O,CCn1nc2c(cc1=O)CN(Cc1nc(-c3ccccn3)no1)CC2,CCn1nc2c(cc1=O)CN(Cc1nc(-c3ccccn3)no1)CC2,Cn1nc2c(cc1=O)CN(Cc1nc(C(C)(C)C)no1)CC2,Cn1nc2c(cc1=O)CN(Cc1nc(C(C)(C)C)no1)CC2,Cn1nc2c(cc1=O)CN(Cc1nnc(C3CC3)o1)CC2,Cn1nc2c(cc1=O)CN(Cc1nnc(C3CC3)o1)CC2 |
[INST] Create new Small molecule for target with these components: {'P9WFT3': 'MSTPTGSRRIFSGVQPTSDSLHLGNALGAVAQWVGLQDDHDAFFCVVDLHAITIPQDPEALRRRTLITAAQYLALGIDPGRATIFVQSQVPAHTQLAWVLGCFTGFGQASRMTQFKDKSARQGSEATTVGLFTYPVLQAADVLAYDTELVPVGEDQRQHLELARDVAQRFNSRFPGTLVVPDVLIPKMTAKIYDLQDPTSKMSKSAGTDAGLINLLDDPALSAKKIRSAVTDSERDIRYDPDVKPGVSNLLNIQSAVTGTDIDVLVDGYAGHGYGDLKKDTAEAVVEFVNPIQARVDELTADPAELEAVLAAGAQRAHDVASKTVQRVYDRLGFLL'}; your molecule must be in SMILES format. [/INST]Cl.NCCC(=O)Nc1ccc(-c2ccccc2)cc1,Cc1noc([C@@H]2C[C@H]3CN(CC4CCOCC4)C[C@H]3O2)n1.O=C(O)C(F)(F)F,COCC1CC2(CCN(C(=O)c3cncc(C)c3)CC2)CO1.O=C(O)C(F)(F)F,CO[C@H]1CC[C@H]2[C@H]1OCCN2C(=O)C1=CCCC1,Cn1nc(C#N)c2c1CN(C(=O)c1ccco1)CCC2,COCC1CC2(CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)CO1,O=C(c1cnccn1)N1CCC2(CCCN(Cc3ccoc3)C2)C1,O=C1NCC[C@]12CN(Cc1ccco1)C[C@H]2c1ccccc1,O=C(CC1CC1)N1CCC2(CC1)C(=O)NCCN2Cc1ccccc1,O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.c1cncc(CN2CCc3ncnc(C4CC4)c3CC2)c1,CCOC1CC2(CCN(Cc3nccn3C)CC2)C1.O=C(O)C(F)(F)F,COCCN(C)C(=O)c1nc2c(s1)CCCN2C,CC(C)NC(=O)c1nc2c(s1)CCCN2C(C)C,O=C([C@H]1COC[C@H]2CN(c3ccncn3)C[C@H]21)N1CCCC1,CO[C@H]1CN(c2ccccc2)S(=O)(=O)[C@@]12CCN(Cc1ccccc1)C2,CC(O)CN1CCC(=O)N(Cc2ccccc2)Cc2ccccc21,COCC(O)CN1CCC(=O)N(Cc2ccco2)Cc2ccccc21,CCCC(O)CN1CC(C)(C)CN(C(=O)CCc2ccccc2)CC1=O,COc1ccccc1C(=O)N1CC(=O)N(CC2CC2)CC(O)C1,O=C1CN(C(=O)c2cccc(C(F)(F)F)c2)CC(O)CN1CC1CC1,N#CCCN1CC(O)CN(C(=O)c2cccc(C(F)(F)F)c2)CC1=O,O=C(C1CC1)N1CCN2C[C@@H](CO)[C@H](c3ccccc3)[C@H]2C1,COc1ccc2c3c1CN(C(C)=O)CC3=CC(C)(C)CO2,CC(C)CC(=O)N1CC(=O)N(CCc2ccccc2)CC(O)C1,CC(C)(C)OC(=O)N1CC(=O)N(CCc2ccccc2)CC(O)C1,CCS(=O)(=O)N1CC(=O)N(Cc2ccccc2OC)CC(O)C1,COc1cccc(CN2CC(O)CN(C(=O)C(C)(C)C)CC2=O)c1OC,CCCS(=O)(=O)N1CC(=O)N(Cc2cccc(OC)c2OC)CC(O)C1,COc1ccccc1CN1CC(O)CN(S(=O)(=O)C(C)C)CC1=O,COc1cccc(OC)c1CN1CC(O)CN(S(C)(=O)=O)CC1=O,COC1CN(C(=O)CC2CCCC2)CCC(=O)N(C)c2ccccc21,CNC(=O)c1cc2ccccc2n1C,COc1ccc(C(=O)Nc2cccc(SC)c2)c(OC)n1,CCCNc1ccc(C(=O)NCCc2cccc(OC)c2)cn1,COc1ccc2c(c1)C(=O)CC1(CCN(Cc3ccc(F)cc3)CC1)O2,NC(=O)CN1CCC2(CC1)CC(=O)c1ccc3ccccc3c1O2,O=C(NCCCn1ccnc1)c1cccnc1OCC(F)(F)F,O=C(NCCc1ccncc1)c1cccnc1OCC(F)(F)F,O=C(c1cccnc1Oc1ccc(Cl)cc1)N1CC[C@@H](O)C1,N#Cc1cnc(N2CCC3(CC2)OCCO3)nc1N,CC(=O)N1N=C(c2ccccc2)OC1C(=O)NCCc1cccc(F)c1,CC(C)c1ccc(-n2ncc(C(=O)NCC3COC(C)(C)O3)c2N)cc1,CC(=O)N1N=C(c2cccs2)OC1C(=O)NCCc1cccc(Cl)c1,CCOC(=O)CNC(=O)C1OC(c2ccccc2)=NN1C(C)=O,Cc1cc(CN(C)CCC(O)c2ccccc2)no1,Nc1c(N2CCCC2)ncnc1N1CCOCC1,CC(=O)c1cc2ncc(C(=O)NC3CC3)cc2[nH]1,CNC(=O)c1cnc2c(C)csc2c1,COc1c(C(=O)N2CCNC(=O)C2)cnc2c1c(C)nn2C,Cn1c(C(=O)NCC2(N)CCCC2)cc2ccccc21,CC(C)(Oc1ccc(C(N)=O)cc1)C(=O)N(CCC#N)CC1CCCO1,CC(C)(C)C(=O)CN1Cc2ccccc2NCCC1=O,COc1ccc2c(c1)CN(Cc1ccco1)C(=O)CCN2,CCN1Cc2cc(F)ccc2N(CC(O)C(F)(F)F)CCC1=O,CC(C)CC(=O)N1CC(=O)N(Cc2ccco2)CC(O)C1,CCCC1CN(CCOc2ccccc2)C(=O)c2cccnc2O1,CCCC1CN(CC(C)C)C(=O)c2cccnc2O1,CC(C)CN1C[C@H](COCc2ccccc2)Oc2ncccc2C1=O,O=C(c1ccco1)N1C(CO)[C@]2(O)CC[C@H]1CC2,O=S(=O)(c1ccccc1)N1C(CN2CCOCC2)[C@]2(O)CC[C@H]1CC2,CS(=O)(=O)NC1CCN(C(=O)NCC2CCCO2)CC1,CC(=O)NC1CCCN(C(=O)CCc2cccnc2)C1,Cc1ccc(S(=O)(=O)NCc2[nH]ncc2Br)cc1F,CCOc1ccc(N(C)Cc2nnc(C)o2)cc1,COCC(O)CNc1cncc(Br)c1,CCCC(O)CNc1cncc(Br)c1,Cc1ccc(CNC(=O)c2ccc(CNS(C)(=O)=O)o2)cc1F,CCOCC(O)CNc1cncc(Br)c1,CS(=O)(=O)NC1CCN(C(=O)CCC2CCCO2)CC1,COCCN1CC(C(=O)N(C)Cc2ccc(Cl)s2)CC1=O,CN(CCc1ccccn1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O,Cc1ccn(-c2ccc(N3CCCN(Cc4ccccc4)CC3)nn2)n1,NC(=O)Nc1cc(F)ccc1SCC(F)F,Cc1cnn(-c2ccc(S(N)(=O)=O)cc2F)c1,Cc1ccc2c(c1C)OCC2NCc1ccc(C#N)cc1,Cn1cccc1CNC(=O)CCCc1nnc2ccccn12,O=C(NS(=O)(=O)c1cccnc1)C1CC(c2ccccc2)=NO1,Cc1cccc(NCc2nc(C)ccc2O)c1,O=C(c1ccccc1)N1CCO[C@@H]2CN(Cc3ccc[nH]3)C[C@@H]2C1,CC(C)N1CCO[C@@H]2CN(C(=O)NCc3ccccc3)CC[C@@H]2C1.O=C(O)C(F)(F)F,CN1CCO[C@@H]2CN(C(=O)NCc3ccccc3)CC[C@@H]2C1.O=C(O)C(F)(F)F,CCn1ncc2c1C(COC)N(C(=O)c1cscn1)CC2.O=C(O)C(F)(F)F,CCn1ncc2c1C(COC)N(C(=O)c1cscn1)CC2.O=C(O)C(F)(F)F,CC(=O)N1CCc2nc(-c3ccc(F)cc3)nc(NC(C)C)c2CC1,CC(=O)N1CCc2nc(-c3ccc(F)cc3)nc(NC(C)C)c2CC1,CN1CCCN(C(=O)c2ccnn2-c2ccc3ccccn23)CC1.O=C(O)C(F)(F)F,CN1CCCN(C(=O)c2ccnn2-c2ccc3ccccn23)CC1.O=C(O)C(F)(F)F,O=C(O)C(F)(F)F.O=C(c1ccco1)N1CCC2(CCCN(c3ncccn3)C2)C1,O=C(O)C(F)(F)F.O=C(c1ccco1)N1CCC2(CCCN(c3ncccn3)C2)C1,CCCS(=O)(=O)N1C[C@@H](c2ccccc2)[C@@]2(CCNC2=O)C1,CCCS(=O)(=O)N1C[C@@H](c2ccccc2)[C@@]2(CCNC2=O)C1,CC(C)N(C)Cc1cncc2c1CCN(Cc1ccoc1)C2.Cl.Cl.Cl,CC(C)N(C)Cc1cncc2c1CCN(Cc1ccoc1)C2.Cl.Cl.Cl,CN(C)Cc1cncc2c1CCN(Cc1ccoc1)C2.Cl.Cl.Cl,CN(C)Cc1cncc2c1CCN(Cc1ccoc1)C2.Cl.Cl.Cl,CCN1CCC2(CC1)CC(CC(=O)N(C)C)c1ccc(F)cc12,CCOCc1cnc2n1CCN(C(=O)c1ccoc1C)C2C,COCC(=O)N1CCO[C@]2(CCC[C@H]2COC)C1,CN1CCN(Cc2cn3c(n2)CN(Cc2ccncc2)CC3)CC1,CS(=O)(=O)CC(=O)N1C[C@H]2CCC[C@@]2(COc2ccccn2)C1.O=C(O)C(F)(F)F |
[INST] Create new Small molecule for target with these components: {}; your molecule must be in SMILES format. [/INST]COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,O=C1CC(c2ccccc2C(F)(F)F)c2sc(N3CCOCC3)nc2N1,O=C1CC(c2ccccc2C(F)(F)F)c2sc(N3CCOCC3)nc2N1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,CC(C)Oc1ccccc1C1CC(=O)Nc2nc(N3CCOCC3)sc21,CC(C)Oc1ccccc1C1CC(=O)Nc2nc(N3CCOCC3)sc21,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,CC[C@H]1N(CC2CCC2)CCC[C@]12CCC(=O)N2Cc1ccncc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CC[C@H]1N(CC2CCC2)CCC[C@]12CCC(=O)N2Cc1ccncc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CCCN1CCC[C@]2(CCC(=O)N2Cc2ccncc2)[C@H]1CC.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CCCN1CCC[C@]2(CCC(=O)N2Cc2ccncc2)[C@H]1CC.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CC[C@@H]1N(C)CCC[C@]12CCC(=O)N2Cc1ccncc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CC[C@@H]1N(C)CCC[C@]12CCC(=O)N2Cc1ccncc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CC[C@@H]1N(CC2CCC2)CCC[C@]12CCC(=O)N2Cc1ccncc1,CC[C@@H]1N(CC2CCC2)CCC[C@]12CCC(=O)N2Cc1ccncc1,O=C(Cc1ccsc1)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,O=C(Cc1ccsc1)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,Cc1ccoc1C(=O)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,Cc1ccoc1C(=O)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,Cc1ccccc1C(=O)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,Cc1ccccc1C(=O)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,O=C(O)C(F)(F)F.O=C(c1ccccc1F)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1,O=C(O)C(F)(F)F.O=C(c1ccccc1F)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1,Cc1ccc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)cn1,Cc1ccc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)cn1,Cc1nc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)cs1,Cc1nc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)cs1,O=C(Cc1cccs1)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,O=C(Cc1cccs1)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1.O=C(O)C(F)(F)F,O=C(c1ncccn1)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1,O=C(c1ncccn1)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1,COCc1nc2cc(NCc3nc(C)cs3)ccc2o1,COCc1nc2cc(NCc3nc(C)cs3)ccc2o1,COCc1nc2cc(NCc3sc(C)nc3C)ccc2o1,COCc1nc2cc(NCc3sc(C)nc3C)ccc2o1,COCc1nc2cc(NCc3scnc3C)ccc2o1,COCc1nc2cc(NCc3scnc3C)ccc2o1,COCc1nc2cc(NCc3ccc(CO)o3)ccc2o1,COCc1nc2cc(NCc3ccc(CO)o3)ccc2o1,COCc1nc2cc(NCc3csc(C)n3)ccc2o1,COCc1nc2cc(NCc3csc(C)n3)ccc2o1,COCc1nc2cc(NCc3ncc[nH]3)ccc2o1,COCc1nc2cc(NCc3ncc[nH]3)ccc2o1,COCc1nc2cc(NCc3cc[nH]n3)ccc2o1,COCc1nc2cc(NCc3cc[nH]n3)ccc2o1,COc1cccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N)sc32)c1OC,CC(C)N1CCC(Cc2cncc(-c3cccc(C(=O)O)c3)n2)C1,CC(C)N1CCC(Cc2cncc(-c3cccc(C(=O)O)c3)n2)C1,CCCN(C(=O)c1ccncc1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1ccncc1)c1nc2c(s1)CCc1c-2cnn1C,COCCN(C(=O)c1ccccn1)c1nc2c(s1)CCc1c-2cnn1C,COCCN(C(=O)c1ccccn1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1cnccn1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1cnccn1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1cnc(C)cn1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1cnc(C)cn1)c1nc2c(s1)CCc1c-2cnn1C,COCCN(C(=O)c1cnccn1)c1nc2c(s1)CCc1c-2cnn1C,COCCN(C(=O)c1cnccn1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1cccnc1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1cccnc1)c1nc2c(s1)CCc1c-2cnn1C,CC(C)N1CCC(Cc2cc(-c3cccc(C(=O)O)c3)ncn2)CC1,CC(C)N1CCC(Cc2cc(-c3cccc(C(=O)O)c3)ncn2)CC1,CC(C)N1CCC(Cc2cncc(-c3cccc(C(=O)O)c3)n2)CC1,CC(C)N1CCC(Cc2cncc(-c3cccc(C(=O)O)c3)n2)CC1,CC[C@H]1NCCC[C@]12CCC(=O)N2Cc1ccncc1,CC[C@H]1NCCC[C@]12CCC(=O)N2Cc1ccncc1,CC[C@H]1N(C)CCC[C@]12CCC(=O)N2Cc1ccncc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CC[C@H]1N(C)CCC[C@]12CCC(=O)N2Cc1ccncc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cn1cc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)cn1,Cn1cc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)cn1,COCCC(=O)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1,COCCC(=O)N1C[C@@H]2COC[C@]2(COCc2cccnc2)C1,Cc1cc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)no1,Cc1cc(C(=O)N2C[C@@H]3COC[C@]3(COCc3cccnc3)C2)no1,CCC(C)CNc1ccc2oc(COC)nc2c1,CCC(C)CNc1ccc2oc(COC)nc2c1,COCc1nc2cc(NCc3ccncc3)ccc2o1,COCc1nc2cc(NCc3ccncc3)ccc2o1,COCc1nc2cc(NCc3ccc(C)o3)ccc2o1,COCc1nc2cc(NCc3ccc(C)o3)ccc2o1,CCCN(C(=O)c1ccccn1)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)c1ccccn1)c1nc2c(s1)CCc1c-2cnn1C,CC(C)N1CCC(Cc2cc(-c3cccc(C(=O)O)c3)ncn2)C1,CC(C)N1CCC(Cc2cc(-c3cccc(C(=O)O)c3)ncn2)C1,CC(C)N1CCC(Cc2cnc(-c3cccc(C(=O)O)c3)cn2)C1,CC(C)N1CCC(Cc2cnc(-c3cccc(C(=O)O)c3)cn2)C1,CCCN(C(=O)COC)c1nc2c(s1)CCc1c-2cnn1C,CCCN(C(=O)COC)c1nc2c(s1)CCc1c-2cnn1C |
[INST] Create new Small molecule for target with these components: {'P32657': 'MAAKDISTEVLQNPELYGLRRSHRAAAHQQNYFNDSDDEDDEDNIKQSRRKRMTTIEDDEDEFEDEEGEEDSGEDEDEEDFEEDDDYYGSPIKQNRSKPKSRTKSKSKSKPKSQSEKQSTVKIPTRFSNRQNKTVNYNIDYSDDDLLESEDDYGSEEALSEENVHEASANPQPEDFHGIDIVINHRLKTSLEEGKVLEKTVPDLNNCKENYEFLIKWTDESHLHNTWETYESIGQVRGLKRLDNYCKQFIIEDQQVRLDPYVTAEDIEIMDMERERRLDEFEEFHVPERIIDSQRASLEDGTSQLQYLVKWRRLNYDEATWENATDIVKLAPEQVKHFQNRENSKILPQYSSNYTSQRPRFEKLSVQPPFIKGGELRDFQLTGINWMAFLWSKGDNGILADEMGLGKTVQTVAFISWLIFARRQNGPHIIVVPLSTMPAWLDTFEKWAPDLNCICYMGNQKSRDTIREYEFYTNPRAKGKKTMKFNVLLTTYEYILKDRAELGSIKWQFMAVDEAHRLKNAESSLYESLNSFKVANRMLITGTPLQNNIKELAALVNFLMPGRFTIDQEIDFENQDEEQEEYIHDLHRRIQPFILRRLKKDVEKSLPSKTERILRVELSDVQTEYYKNILTKNYSALTAGAKGGHFSLLNIMNELKKASNHPYLFDNAEERVLQKFGDGKMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLVSKDTVEEEVLERARKKMILEYAIISLGVTDGNKYTKKNEPNAGELSAILKFGAGNMFTATDNQKKLEDLNLDDVLNHAEDHVTTPDLGESHLGGEEFLKQFEVTDYKADIDWDDIIPEEELKKLQDEEQKRKDEEYVKEQLEMMNRRDNALKKIKNSVNGDGTAANSDSDDDSTSRSSRRRARANDMDSIGESEVRALYKAILKFGNLKEILDELIADGTLPVKSFEKYGETYDEMMEAAKDCVHEEEKNRKEILEKLEKHATAYRAKLKSGEIKAENQPKDNPLTRLSLKKREKKAVLFNFKGVKSLNAESLLSRVEDLKYLKNLINSNYKDDPLKFSLGNNTPKPVQNWSSNWTKEEDEKLLIGVFKYGYGSWTQIRDDPFLGITDKIFLNEVHNPVAKKSASSSDTTPTPSKKGKGITGSSKKVPGAIHLGRRVDYLLSFLRGGLNTKSPSADIGSKKLPTGPSKKRQRKPANHSKSMTPEITSSEPANGPPSKRMKALPKGPAALINNTRLSPNSPTPPLKSKVSRDNGTRQSSNPSSGSAHEKEYDSMDEEDCRHTMSAIRTSLKRLRRGGKSLDRKEWAKILKTELTTIGNHIESQKGSSRKASPEKYRKHLWSYSANFWPADVKSTKLMAMYDKITESQKK'}; your molecule must be in SMILES format. [/INST]O=C1CSC(c2cccs2)c2cnn(C3CCCC3)c2N1,O=C1CSC(c2cccs2)c2cnn(C3CCCC3)c2N1,COc1ccc(C2=C(C)C(N3CCc4ccccc4C3)=NS2(=O)=O)cc1,COc1ccc(C2=C(C)C(N3CCc4ccccc4C3)=NS2(=O)=O)cc1,Cc1cccc(NC(=O)Cn2ncc(SCC(N)=O)c(Cl)c2=O)c1C,Cc1cccc(NC(=O)Cn2ncc(SCC(N)=O)c(Cl)c2=O)c1C,COc1ccc(C)cc1S(=O)(=O)NCC(c1cccn1C)N(C)C,COc1ccc(C)cc1S(=O)(=O)NCC(c1cccn1C)N(C)C,Cc1ccc(CNC(=O)CN2CCN(CC(O)C3CC3)CC2)cc1.Cl.Cl,Cc1ccc(CNC(=O)CN2CCN(CC(O)C3CC3)CC2)cc1.Cl.Cl,COc1ncccc1C(=O)Nc1nc2c(s1)CN(S(=O)(=O)C1CC1)CC2,COc1ncccc1C(=O)Nc1nc2c(s1)CN(S(=O)(=O)C1CC1)CC2,COC(=O)N1CCc2ccc(NC(=O)c3cn(C)nn3)cc2C1,COC(=O)N1CCc2ccc(NC(=O)c3cn(C)nn3)cc2C1,O=C(c1ccnnc1)N1C[C@@H](OCC2CCOCC2)[C@H]2OCCC[C@H]21,O=C(c1ccnnc1)N1C[C@@H](OCC2CCOCC2)[C@H]2OCCC[C@H]21,CSCCC(=O)N1CCCC1c1ccsc1,CSCCC(=O)N1CCCC1c1ccsc1,CCc1cnc(CN(C)C2CCN(CCc3ccccn3)C2)o1,CCc1cnc(CN(C)C2CCN(CCc3ccccn3)C2)o1,CN(C)C(C)(C)CNC(=O)C(C)(C)c1ccccc1F,CN(C)C(C)(C)CNC(=O)C(C)(C)c1ccccc1F,COc1ccc(CNC(=O)C2(C#N)CCCC2)cc1,COc1ccc(CNC(=O)C2(C#N)CCCC2)cc1,CCOc1ncccc1NC(=O)c1cc2c(s1)CCC2,CCOc1ncccc1NC(=O)c1cc2c(s1)CCC2,O=C(Nc1cccc(CN2CCOC2=O)c1)N1CCSCC1,O=C(Nc1cccc(CN2CCOC2=O)c1)N1CCSCC1,CC(C)NC(=O)c1nnn(-c2cccc(C(F)(F)F)c2)c1C1CC1,CC(C)NC(=O)c1nnn(-c2cccc(C(F)(F)F)c2)c1C1CC1,CCCN(CC(=O)NC)C(=O)c1ccc(-c2ccsc2)nc1C,CCCN(CC(=O)NC)C(=O)c1ccc(-c2ccsc2)nc1C,Cc1ccccc1CC(C)NCc1c(C)nn(C)c1N1CCOCC1.Cl,Cc1ccccc1CC(C)NCc1c(C)nn(C)c1N1CCOCC1.Cl,N#Cc1c(F)cccc1N1CCN(S(=O)(=O)c2cccs2)CC1,N#Cc1c(F)cccc1N1CCN(S(=O)(=O)c2cccs2)CC1,CC(NC(=O)CCCOc1ccccc1Cl)c1ccncc1,CC(NC(=O)CCCOc1ccccc1Cl)c1ccncc1,CSCC(CCO)NC(=O)Nc1cc(Br)ccc1C,CSCC(CCO)NC(=O)Nc1cc(Br)ccc1C,O=C(NCC(O)c1ccccc1Cl)c1cccc(-n2cnnn2)c1,O=C(NCC(O)c1ccccc1Cl)c1cccc(-n2cnnn2)c1,CCN(CC)CCNC(=O)c1cc(C(C)C)nc(N2CCCC2)n1,CCN(CC)CCNC(=O)c1cc(C(C)C)nc(N2CCCC2)n1,Cc1nn(C)c(C)c1NC(=O)CCn1ncc2c(C)cccc21,Cc1nn(C)c(C)c1NC(=O)CCn1ncc2c(C)cccc21,Nc1ncc2c(n1)CN(C1CCCC1)C2=O,Nc1ncc2c(n1)CN(C1CCCC1)C2=O,CCS(=O)(=O)Nc1ccn(Cc2cccc(Cl)c2)n1,CCS(=O)(=O)Nc1ccn(Cc2cccc(Cl)c2)n1,CCOc1ccc(N2CCCN=C2NC(=O)c2ccccc2C)cc1,CCOc1ccc(N2CCCN=C2NC(=O)c2ccccc2C)cc1,O=C(COCc1nc(-c2ccncc2)no1)N1CCCCCC1,O=C(COCc1nc(-c2ccncc2)no1)N1CCCCCC1,Cn1ccc(NC(=O)Cc2cccc(F)c2)n1,Cn1ccc(NC(=O)Cc2cccc(F)c2)n1,Cc1cc(C)n(CC2CN(Cc3cccc(C(N)=O)c3)CCO2)n1,Cc1cc(C)n(CC2CN(Cc3cccc(C(N)=O)c3)CCO2)n1,CNc1cc(N2CCCC2CNCc2ccc(Cl)o2)ncn1,CNc1cc(N2CCCC2CNCc2ccc(Cl)o2)ncn1,COCCNC(=O)C(C)n1cc(Br)cn1,COCCNC(=O)C(C)n1cc(Br)cn1,CCn1nccc1CNC(=O)C1CC1,CCn1nccc1CNC(=O)C1CC1,Cc1cc(NC(=O)NCCc2ccsc2)n(C)n1,Cc1cc(NC(=O)NCCc2ccsc2)n(C)n1,Cc1cc(CN(C)C(=O)NC(C)c2nncn2C)no1,Cc1cc(CN(C)C(=O)NC(C)c2nncn2C)no1,O=C(Cn1cc(-c2ccccc2)ncc1=O)Nc1ccncc1,O=C(Cn1cc(-c2ccccc2)ncc1=O)Nc1ccncc1,O=C(Cn1cc(-c2ccccc2)ncc1=O)Nc1nnc[nH]1,O=C(Cn1cc(-c2ccccc2)ncc1=O)Nc1nnc[nH]1,O=C(Cn1c(=O)nc2n1C(=O)N(c1ccccc1)C2)Nc1ccccc1,O=C(Cn1c(=O)nc2n1C(=O)N(c1ccccc1)C2)Nc1ccccc1,CC(C)(C)n1ncc2c1NC(=O)CC2c1ccccc1,CC(C)(C)n1ncc2c1NC(=O)CC2c1ccccc1,O=C1CC(c2ccco2)c2sc(C(=O)O)c(-c3ccccc3)c2N1,O=C1CC(c2ccco2)c2sc(C(=O)O)c(-c3ccccc3)c2N1,O=C1CSC(c2ccsc2)c2sccc2N1,O=C1CSC(c2ccsc2)c2sccc2N1,O=C(NS(=O)(=O)c1ccccc1Cl)c1cccc2c1OCCO2,O=C(NS(=O)(=O)c1ccccc1Cl)c1cccc2c1OCCO2,CC(c1cccnc1)N(C)Cc1csc(-c2ccccn2)n1,CC(c1cccnc1)N(C)Cc1csc(-c2ccccn2)n1,CN1CCN(c2ncc3c(=O)n(-c4cccc(F)c4)c(=O)[nH]c3n2)CC1,CN1CCN(c2ncc3c(=O)n(-c4cccc(F)c4)c(=O)[nH]c3n2)CC1,CCc1ccc(-n2c(=O)[nH]c3nc(N4CCSCC4)ncc3c2=O)cc1,CCc1ccc(-n2c(=O)[nH]c3nc(N4CCSCC4)ncc3c2=O)cc1,O=C(O)c1nnn(-c2ccc(OC(F)(F)F)cc2)c1-c1ccncc1,O=C(O)c1nnn(-c2ccc(OC(F)(F)F)cc2)c1-c1ccncc1,COCCC(=O)N1CCc2cc(Cl)cc(Cl)c2C1,COCCC(=O)N1CCc2cc(Cl)cc(Cl)c2C1,O=C(COc1coc(CN2CCCCCC2)cc1=O)c1ccccc1,O=C(COc1coc(CN2CCCCCC2)cc1=O)c1ccccc1,CC(=O)c1cccc(NC(=O)Cn2cc(I)cn2)c1,CC(=O)c1cccc(NC(=O)Cn2cc(I)cn2)c1,CN(Cc1cccc(F)c1)C(=O)CN1CCCC1CCc1ccccc1,CN(Cc1cccc(F)c1)C(=O)CN1CCCC1CCc1ccccc1,Cc1c(C(=O)NCC2CCCO2)nnn1-c1cccc2c1CCN(C)C2,Cc1c(C(=O)NCC2CCCO2)nnn1-c1cccc2c1CCN(C)C2 |
[INST] Create new Small molecule for target with these components: {}; your molecule must be in SMILES format. [/INST]COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,CNc1nc2c(s1)C(c1cc(Cl)ccc1F)CC(=O)N2,CNc1nc2c(s1)C(c1cc(Cl)ccc1F)CC(=O)N2,O=C1CC(c2ccccc2C(F)(F)F)c2sc(N3CCOCC3)nc2N1,O=C1CC(c2ccccc2C(F)(F)F)c2sc(N3CCOCC3)nc2N1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,Nc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,Nc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,CC(C)Oc1ccccc1C1CC(=O)Nc2nc(N3CCOCC3)sc21,CC(C)Oc1ccccc1C1CC(=O)Nc2nc(N3CCOCC3)sc21,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,CNc1nc2c(s1)C(c1ccc(F)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccc(F)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1cccc(Cl)c1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1cccc(Cl)c1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccc(Cl)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccc(Cl)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,Cc1ccc(N2CCCC3(COCCN(c4ccccn4)C3)C2)nn1.O=C(O)C(F)(F)F,Cc1ccc(N2CCCC3(COCCN(c4ccccn4)C3)C2)nn1.O=C(O)C(F)(F)F,Cc1ccc(N2CCOCC3(CCCN(c4ncc(F)cn4)C3)C2)nn1,Cc1ccc(N2CCOCC3(CCCN(c4ncc(F)cn4)C3)C2)nn1,Cc1cnc(N2CCCC3(COCCN(c4ccc(C)nn4)C3)C2)nc1,Cc1cnc(N2CCCC3(COCCN(c4ccc(C)nn4)C3)C2)nc1,Cc1ccc(N2CCCC3(COCCN(c4ncccn4)C3)C2)nn1.O=C(O)C(F)(F)F,Cc1ccc(N2CCCC3(COCCN(c4ncccn4)C3)C2)nn1.O=C(O)C(F)(F)F,Cc1ccc(N2CCCC3(COCCN(c4cnccn4)C3)C2)nn1,Cc1ccc(N2CCCC3(COCCN(c4cnccn4)C3)C2)nn1,Cc1ccc(N2Cc3c(CN(C)C)nn(C)c3C2)nn1,Cc1ccc(N2Cc3c(CN(C)C)nn(C)c3C2)nn1,Cn1nc(Cn2ccnc2)c2c1CN(c1nccs1)C2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cn1nc(Cn2ccnc2)c2c1CN(c1nccs1)C2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cn1nc(Cn2ccnc2)c2c1CN(c1ncccn1)C2.O=C(O)C(F)(F)F,Cn1nc(Cn2ccnc2)c2c1CN(c1ncccn1)C2.O=C(O)C(F)(F)F,c1ccc(N2CCOCC3(CCCN(c4nccs4)C3)C2)nc1,c1ccc(N2CCOCC3(CCCN(c4nccs4)C3)C2)nc1,Cc1ccc(N2CCC3(CC2)COCCN(c2nccs2)C3)nn1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1ccc(N2CCC3(CC2)COCCN(c2nccs2)C3)nn1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,COCCN1CCC2(CCN(c3ncccn3)CC2)C1=O.O=C(O)C(F)(F)F,COCCN1CCC2(CCN(c3ncccn3)CC2)C1=O.O=C(O)C(F)(F)F,CCN1CCC2(CCN(c3ncccn3)CC2)C1=O.O=C(O)C(F)(F)F,CCN1CCC2(CCN(c3ncccn3)CC2)C1=O.O=C(O)C(F)(F)F,Cc1cnc(N2CCC3(CCN(CC4CCCC4)C3=O)CC2)nc1.O=C(O)C(F)(F)F,Cc1cnc(N2CCC3(CCN(CC4CCCC4)C3=O)CC2)nc1.O=C(O)C(F)(F)F,O=C(O)C(F)(F)F.O=C1N(CC2CCCC2)CCC12CCN(c1ncc(F)cn1)CC2,O=C(O)C(F)(F)F.O=C1N(CC2CCCC2)CCC12CCN(c1ncc(F)cn1)CC2,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2cccc(Cl)c2)c1C,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2cccc(Cl)c2)c1C,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2ccc(Cl)cc2)c1C,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2ccc(Cl)cc2)c1C,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2ccccc2Br)c1C,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2ccccc2Br)c1C,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2ccccc2Cl)c1C,CCN(CC)CCNC(=O)CCc1c(C)nn(-c2ccccc2Cl)c1C,Cc1nn(-c2ccccc2Cl)c(C)c1CCC(=O)NCCS(C)(=O)=O,Cc1nn(-c2ccccc2Cl)c(C)c1CCC(=O)NCCS(C)(=O)=O,CC1CCN(C(=O)c2ccc(N3CCCC3c3nncn3C)nc2)CC1,CC1CCN(C(=O)c2ccc(N3CCCC3c3nncn3C)nc2)CC1,CC(C)C1CCCN1C(=O)Nc1ccc(=O)n(C)c1,CC(C)C1CCCN1C(=O)Nc1ccc(=O)n(C)c1,Cn1cc(NC(=O)N2CCCC2c2ccccn2)ccc1=O,Cn1cc(NC(=O)N2CCCC2c2ccccn2)ccc1=O,Cn1cc(NC(=O)N2CCCC2c2cccnc2)ccc1=O,Cn1cc(NC(=O)N2CCCC2c2cccnc2)ccc1=O,Cc1nc(CNC2CCCN(c3cccnn3)C2)no1,Cc1nc(CNC2CCCN(c3cccnn3)C2)no1,c1cncc(-c2noc(CNC3CCCN(c4cccnn4)C3)n2)c1,c1cncc(-c2noc(CNC3CCCN(c4cccnn4)C3)n2)c1,c1ccc(-c2nc(CNC3CCCN(c4cccnn4)C3)no2)cc1,c1ccc(-c2nc(CNC3CCCN(c4cccnn4)C3)no2)cc1,CC(C)(C)c1nc(CNC2CCCN(c3cccnn3)C2)no1,CC(C)(C)c1nc(CNC2CCCN(c3cccnn3)C2)no1,c1cnnc(N2CCCC(NCc3nc(-c4ccsc4)no3)C2)c1,c1cnnc(N2CCCC(NCc3nc(-c4ccsc4)no3)C2)c1,c1cnnc(N2CCCC(NCc3nc(-c4cccs4)no3)C2)c1,c1cnnc(N2CCCC(NCc3nc(-c4cccs4)no3)C2)c1,c1ccc(-c2noc(CNC3CCCN(c4cccnn4)C3)n2)nc1,c1ccc(-c2noc(CNC3CCCN(c4cccnn4)C3)n2)nc1,CCCn1cc(NC(=O)c2ccc(NC(=O)NC3CC3)cc2)ccc1=O,CCCn1cc(NC(=O)c2ccc(NC(=O)NC3CC3)cc2)ccc1=O,CCCn1cc(NC(=O)c2ccc(N(C)CC)cc2)ccc1=O,CCCn1cc(NC(=O)c2ccc(N(C)CC)cc2)ccc1=O,CCCn1cc(NC(=O)c2ccncc2)ccc1=O,CCCn1cc(NC(=O)c2ccncc2)ccc1=O,CCCn1cc(NC(=O)c2ccc(S(=O)(=O)CC)cc2)ccc1=O,CCCn1cc(NC(=O)c2ccc(S(=O)(=O)CC)cc2)ccc1=O,CCCn1cc(NC(=O)c2cccnc2O)ccc1=O,CCCn1cc(NC(=O)c2cccnc2O)ccc1=O |
[INST] Create new Small molecule for target with these components: {}; your molecule must be in SMILES format. [/INST]O=C(c1cnccn1)N1C[C@@H]2[C@@H](C1)OCC(=O)N2CC1CCCC1,O=C(c1cnccn1)N1C[C@@H]2[C@@H](C1)OCC(=O)N2CC1CCCC1,CCC1CN(CC(=O)NCCN2CCCCCC2)c2ccccc2S1,CCC1CN(CC(=O)NCCN2CCCCCC2)c2ccccc2S1,CN1CCCN(C(=O)c2nc3c(s2)CCCN3CC2CC2)CC1,CN1CCCN(C(=O)c2nc3c(s2)CCCN3CC2CC2)CC1,Cc1nc(N2CCCC2)nc2c1CCN(C(=O)C1CCC1)CC2,Cc1nc(N2CCCC2)nc2c1CCN(C(=O)C1CCC1)CC2,COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,Nc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,Nc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,CS(=O)(=O)N1CCC2(CC1)CN(CCn1cccn1)C(=O)CO2,CS(=O)(=O)N1CCC2(CC1)CN(CCn1cccn1)C(=O)CO2,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,CNc1nc2c(s1)C(c1ccc(Cl)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccc(Cl)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,O=C(NCc1ccco1)[C@@H]1CC[C@@H]2[C@@H](CCN2Cc2ccc(F)cc2)O1.O=C(O)C(F)(F)F,O=C(NCc1ccco1)[C@@H]1CC[C@@H]2[C@@H](CCN2Cc2ccc(F)cc2)O1.O=C(O)C(F)(F)F,CCC1CCc2c(c3ccccc3[nH]c2=O)O1,CCC1CCc2c(c3ccccc3[nH]c2=O)O1,O=C(O)C(F)(F)F.O=C(c1ccc2[nH]ccc2c1)N1Cc2nc(CN3CCCCC3)oc2C1,O=C(O)C(F)(F)F.O=C(c1ccc2[nH]ccc2c1)N1Cc2nc(CN3CCCCC3)oc2C1,O=C(c1nc2c(s1)CCCN2CC1CC1)N1CCOCC1,O=C(c1nc2c(s1)CCCN2CC1CC1)N1CCOCC1,COCCn1cc(-c2cc(C(=O)N3CCCC3)c3ccccn23)nc1C,COCCn1cc(-c2cc(C(=O)N3CCCC3)c3ccccn23)nc1C,O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.c1cncc(-c2ccc3c(c2)CCC32CCN(Cc3nccs3)CC2)c1,O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.c1cncc(-c2ccc3c(c2)CCC32CCN(Cc3nccs3)CC2)c1,Cc1[nH]/c(=N\C(=O)c2csc(NC3CCCC3)n2)sc1C,Cc1[nH]/c(=N\C(=O)c2csc(NC3CCCC3)n2)sc1C,Cc1cs/c(=N/C(=O)c2csc(NCC(C)C)n2)[nH]1,Cc1cs/c(=N/C(=O)c2csc(NCC(C)C)n2)[nH]1,Cc1ccc2[nH]c(CO[C@H]3CN(c4ccc(C#N)cn4)C[C@H]3F)nc2c1,Cc1ccc2[nH]c(CO[C@H]3CN(c4ccc(C#N)cn4)C[C@H]3F)nc2c1,Cc1cc(C(=O)N2CC[C@@H](N(C)C)[C@@H]2Cc2ccccc2)no1.O=C(O)C(F)(F)F,Cc1cc(C(=O)N2CC[C@@H](N(C)C)[C@@H]2Cc2ccccc2)no1.O=C(O)C(F)(F)F,Cn1nc(Cn2ccnc2)c2c1CN(c1nccs1)C2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cn1nc(Cn2ccnc2)c2c1CN(c1nccs1)C2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1ccc(N2CCC3(CC2)COCCN(c2nccs2)C3)nn1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1ccc(N2CCC3(CC2)COCCN(c2nccs2)C3)nn1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1nc(CN2CCc3nc(N4CCCC4)nc(NC(C)C)c3C2)cs1,Cc1nc(CN2CCc3nc(N4CCCC4)nc(NC(C)C)c3C2)cs1,Cc1ccc(N2CCc3sc(C(=O)N4CCOCC4)cc32)nn1,Cc1ccc(N2CCc3sc(C(=O)N4CCOCC4)cc32)nn1,CC(=O)c1c(C)nn(CC(=O)Nc2ccc(Br)cc2)c1C,CC(=O)c1c(C)nn(CC(=O)Nc2ccc(Br)cc2)c1C,COc1ccc(NC(=O)Cn2nc(C)c(C(C)=O)c2C)cc1,COc1ccc(NC(=O)Cn2nc(C)c(C(C)=O)c2C)cc1,Cc1nc(CN2CCc3nc(NC(C)C)nc(C)c3C2)cs1,Cc1nc(CN2CCc3nc(NC(C)C)nc(C)c3C2)cs1,Fc1ccc(N2CCC3(CC2)CC(OCc2cccnc2)CO3)cc1.O=C(O)C(F)(F)F,Fc1ccc(N2CCC3(CC2)CC(OCc2cccnc2)CO3)cc1.O=C(O)C(F)(F)F,O=C(O)C(F)(F)F.c1cc(-c2ccc3c(c2)CCC32CCN(c3nncs3)CC2)ccn1,O=C(O)C(F)(F)F.c1cc(-c2ccc3c(c2)CCC32CCN(c3nncs3)CC2)ccn1,O=C(C1=NN(Cc2ccccc2)c2ccccc2S1(=O)=O)N1CCCC1,O=C(C1=NN(Cc2ccccc2)c2ccccc2S1(=O)=O)N1CCCC1,Cc1ccc(CN2CCn3c(CNC(=O)c4cccn4C)cnc3C2)s1.O=C(O)C(F)(F)F,Cc1ccc(CN2CCn3c(CNC(=O)c4cccn4C)cnc3C2)s1.O=C(O)C(F)(F)F,c1cc(-c2ccc3c(c2)CCC32CCN(c3nncs3)CC2)co1,c1cc(-c2ccc3c(c2)CCC32CCN(c3nncs3)CC2)co1,c1cc(-c2ccc3c(c2)C2(CC3)CCN(c3nncs3)CC2)ccn1,c1cc(-c2ccc3c(c2)C2(CC3)CCN(c3nncs3)CC2)ccn1,O=C(C1CCCCC1)N1C[C@@H]2CCN(c3cnccn3)C[C@@H]2C1.O=C(O)C(F)(F)F,O=C(C1CCCCC1)N1C[C@@H]2CCN(c3cnccn3)C[C@@H]2C1.O=C(O)C(F)(F)F,O=C(Nc1cccnc1)C1Cc2nc(-c3ccsc3)sc2N1CC1CC1.O=C(O)C(F)(F)F,O=C(Nc1cccnc1)C1Cc2nc(-c3ccsc3)sc2N1CC1CC1.O=C(O)C(F)(F)F,Cc1ccc(CNC(=O)c2nc3c(o2)CN(C(=O)c2cccnc2)C3)o1.O=C(O)C(F)(F)F,Cc1ccc(CNC(=O)c2nc3c(o2)CN(C(=O)c2cccnc2)C3)o1.O=C(O)C(F)(F)F,CC(=O)NCC(=O)N1Cc2nccn2CC(COc2cccnc2)C1.O=C(O)C(F)(F)F,CC(=O)NCC(=O)N1Cc2nccn2CC(COc2cccnc2)C1.O=C(O)C(F)(F)F,CC(C)NC(=O)C1Cc2nc(-c3ccsc3)sc2N1CC1CC1,CC(C)NC(=O)C1Cc2nc(-c3ccsc3)sc2N1CC1CC1,c1cc(-c2nnc3sc(CCN4CCCC4)nn23)ccn1,c1cc(-c2nnc3sc(CCN4CCCC4)nn23)ccn1,Cc1nn(-c2ccccn2)c(C)c1[C@@H]1C=C[C@@H](NC(=O)NC(C)C)C1,Cc1nn(-c2ccccn2)c(C)c1[C@@H]1C=C[C@@H](NC(=O)NC(C)C)C1,c1cc(-c2ccc3c(c2)CCC32CCNCC2)ccn1,c1cc(-c2ccc3c(c2)CCC32CCNCC2)ccn1,N#Cc1ccc(N2CCCC3(CCN(c4cccnc4)CC3)C2)cc1.O=C(O)C(F)(F)F,N#Cc1ccc(N2CCCC3(CCN(c4cccnc4)CC3)C2)cc1.O=C(O)C(F)(F)F |
[INST] Create new Small molecule for target with these components: {}; your molecule must be in SMILES format. [/INST]COc1ccc(C2SC(C)=Nc3c2c(=O)[nH]n3C2CCCCC2)cc1O,COc1ccc(C2SC(C)=Nc3c2c(=O)[nH]n3C2CCCCC2)cc1O,COc1ccc(C2SC(C)=Nc3c2c(=O)[nH]n3C2CCCCC2)cc1O,COc1ccc(C2SC(C)=Nc3c2c(=O)[nH]n3C2CCCCC2)cc1O,Cc1cc(C)n(C2CN(CC(=O)N(C)Cc3ccc(C)o3)C2)n1,Cc1cc(C)n(C2CN(CC(=O)N(C)Cc3ccc(C)o3)C2)n1,Cc1cc(C)n(C2CN(CC(=O)N(C)Cc3ccc(C)o3)C2)n1,Cc1cc(C)n(C2CN(CC(=O)N(C)Cc3ccc(C)o3)C2)n1,CC(C)NC(=O)N1CCN(CC2CC2)CC2(CC(=O)N(C)C2)C1.O=C(O)C(F)(F)F,CC(C)NC(=O)N1CCN(CC2CC2)CC2(CC(=O)N(C)C2)C1.O=C(O)C(F)(F)F,CC(C)NC(=O)N1CCN(CC2CC2)CC2(CC(=O)N(C)C2)C1.O=C(O)C(F)(F)F,CC(C)NC(=O)N1CCN(CC2CC2)CC2(CC(=O)N(C)C2)C1.O=C(O)C(F)(F)F,COCCN1C[C@@H]2CN(c3ncccn3)C[C@@H]2C1=O,COCCN1C[C@@H]2CN(c3ncccn3)C[C@@H]2C1=O,COCCN1C[C@@H]2CN(c3ncccn3)C[C@@H]2C1=O,COCCN1C[C@@H]2CN(c3ncccn3)C[C@@H]2C1=O,CC(=O)N1CCN(c2ccc3ccc(C(=O)NC4CCCC4)cn23)CC1,CC(=O)N1CCN(c2ccc3ccc(C(=O)NC4CCCC4)cn23)CC1,CC(=O)N1CCN(c2ccc3ccc(C(=O)NC4CCCC4)cn23)CC1,CC(=O)N1CCN(c2ccc3ccc(C(=O)NC4CCCC4)cn23)CC1,O=C(NC1CC1)c1ccc2ccc(N3CCN(CC4CC4)CC3)n2c1,O=C(NC1CC1)c1ccc2ccc(N3CCN(CC4CC4)CC3)n2c1,O=C(NC1CC1)c1ccc2ccc(N3CCN(CC4CC4)CC3)n2c1,O=C(NC1CC1)c1ccc2ccc(N3CCN(CC4CC4)CC3)n2c1,CN(CC1CC1)c1ccc2ccc(C(=O)NCCN3CCOCC3)cn12,CN(CC1CC1)c1ccc2ccc(C(=O)NCCN3CCOCC3)cn12,CN(CC1CC1)c1ccc2ccc(C(=O)NCCN3CCOCC3)cn12,CN(CC1CC1)c1ccc2ccc(C(=O)NCCN3CCOCC3)cn12,O=C(O)C(F)(F)F.c1cnc(N2CCC3(CC2)CN(CC2CC2)c2ccccc23)nc1,O=C(O)C(F)(F)F.c1cnc(N2CCC3(CC2)CN(CC2CC2)c2ccccc23)nc1,O=C(O)C(F)(F)F.c1cnc(N2CCC3(CC2)CN(CC2CC2)c2ccccc23)nc1,O=C(O)C(F)(F)F.c1cnc(N2CCC3(CC2)CN(CC2CC2)c2ccccc23)nc1,O=C(C1=CCCC1)N1C[C@H](Oc2cccnc2)[C@H]2OCCC[C@H]21,O=C(C1=CCCC1)N1C[C@H](Oc2cccnc2)[C@H]2OCCC[C@H]21,O=C(C1=CCCC1)N1C[C@H](Oc2cccnc2)[C@H]2OCCC[C@H]21,O=C(C1=CCCC1)N1C[C@H](Oc2cccnc2)[C@H]2OCCC[C@H]21,O=C(NCc1ccccc1)N1CCC2(CC(=O)N(c3ccsc3)C2)C1,O=C(NCc1ccccc1)N1CCC2(CC(=O)N(c3ccsc3)C2)C1,O=C(NCc1ccccc1)N1CCC2(CC(=O)N(c3ccsc3)C2)C1,O=C(NCc1ccccc1)N1CCC2(CC(=O)N(c3ccsc3)C2)C1,CNC(=O)[C@H]1CCS(=O)(=O)[C@@H]2CN(Cc3ccc(OC)cc3)C[C@H]12,CNC(=O)[C@H]1CCS(=O)(=O)[C@@H]2CN(Cc3ccc(OC)cc3)C[C@H]12,CNC(=O)[C@H]1CCS(=O)(=O)[C@@H]2CN(Cc3ccc(OC)cc3)C[C@H]12,CNC(=O)[C@H]1CCS(=O)(=O)[C@@H]2CN(Cc3ccc(OC)cc3)C[C@H]12,CN1CCc2nc(C3CCN(C(=O)CCC4CCCC4)CC3)ncc2C1,CN1CCc2nc(C3CCN(C(=O)CCC4CCCC4)CC3)ncc2C1,CN1CCc2nc(C3CCN(C(=O)CCC4CCCC4)CC3)ncc2C1,CN1CCc2nc(C3CCN(C(=O)CCC4CCCC4)CC3)ncc2C1,NC[C@H]1CC[C@H](C(NC(=O)c2cccc(F)c2)c2ccccn2)CC1,NC[C@H]1CC[C@H](C(NC(=O)c2cccc(F)c2)c2ccccn2)CC1,NC[C@H]1CC[C@H](C(NC(=O)c2cccc(F)c2)c2ccccn2)CC1,NC[C@H]1CC[C@H](C(NC(=O)c2cccc(F)c2)c2ccccn2)CC1,CNC(=O)C1(c2cnccn2)CCCN1C(=O)c1ccn(C)n1,CNC(=O)C1(c2cnccn2)CCCN1C(=O)c1ccn(C)n1,CNC(=O)C1(c2cnccn2)CCCN1C(=O)c1ccn(C)n1,CNC(=O)C1(c2cnccn2)CCCN1C(=O)c1ccn(C)n1,Fc1cccc(Oc2ccc(CNCC3CNc4ccnn4C3)cn2)c1,Fc1cccc(Oc2ccc(CNCC3CNc4ccnn4C3)cn2)c1,Fc1cccc(Oc2ccc(CNCC3CNc4ccnn4C3)cn2)c1,Fc1cccc(Oc2ccc(CNCC3CNc4ccnn4C3)cn2)c1,Cc1cccnc1NC(=O)NCc1ccc(N2CCNC(=O)C2)cc1,Cc1cccnc1NC(=O)NCc1ccc(N2CCNC(=O)C2)cc1,Cc1cccnc1NC(=O)NCc1ccc(N2CCNC(=O)C2)cc1,Cc1cccnc1NC(=O)NCc1ccc(N2CCNC(=O)C2)cc1,CN(CCCOc1ccccc1)C(=O)CN1CCc2cncnc2C1,CN(CCCOc1ccccc1)C(=O)CN1CCc2cncnc2C1,CN(CCCOc1ccccc1)C(=O)CN1CCc2cncnc2C1,CN(CCCOc1ccccc1)C(=O)CN1CCc2cncnc2C1,Fc1ccc(OCc2noc(CN3CCc4cncnc4C3)n2)cc1,Fc1ccc(OCc2noc(CN3CCc4cncnc4C3)n2)cc1,Fc1ccc(OCc2noc(CN3CCc4cncnc4C3)n2)cc1,Fc1ccc(OCc2noc(CN3CCc4cncnc4C3)n2)cc1 |
[INST] Create new Small molecule for target with these components: {'P9WNZ1': 'MVDHKRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSGEPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLARAAAGRADDLLTATLLTARCPVLFAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQLLLERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIAGHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIKKGVEGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLRRKGCDLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAIVTFLAGCSS'}; your molecule must be in SMILES format. [/INST]CNC(=O)[C@@]12CCC3(CCN(S(=O)(=O)C4CC4)CC3)[C@@H]1CN(C(C)=O)C2,CNC(=O)[C@@]12CCC3(CCN(S(=O)(=O)C4CC4)CC3)[C@@H]1CN(C(C)=O)C2,COCC1CN(Cc2ccsc2)Cc2cnn(C)c21,COCC1CN(Cc2ccsc2)Cc2cnn(C)c21,CC1c2ncc(Cn3cncn3)n2CCN1C(=O)c1ccsc1,CC1c2ncc(Cn3cncn3)n2CCN1C(=O)c1ccsc1,CCS(=O)(=O)c1ccc2oc([C@H]3CCN(Cc4ccccn4)C3)nc2c1,CCS(=O)(=O)c1ccc2oc([C@H]3CCN(Cc4ccccn4)C3)nc2c1,O=C(NC[C@H]1OC[C@@H](NCc2ccc(F)cc2)[C@@H]1O)N1CCOCC1,O=C(NC[C@H]1OC[C@@H](NCc2ccc(F)cc2)[C@@H]1O)N1CCOCC1,Cc1cccc(-c2cc(C(=O)O)sn2)c1,Cc1cccc(-c2cc(C(=O)O)sn2)c1,Cc1cccc(-c2cc(C(=O)O)sn2)c1,Cc1cccc(-c2cc(C(=O)O)sn2)c1,Cc1c(C(=O)N2CCN(c3ccccn3)CC2)n(C)c2ccc(Cl)cc12,Cc1c(C(=O)N2CCN(c3ccccn3)CC2)n(C)c2ccc(Cl)cc12,COc1ccccc1C1CC(=O)Nc2c1c(=O)[nH]n2C1CCCC1,COc1ccccc1C1CC(=O)Nc2c1c(=O)[nH]n2C1CCCC1,Cc1ccc(CN2C[C@@H]3CCN(Cc4ccncc4)C(=O)[C@H]3C2)s1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1ccc(CN2C[C@@H]3CCN(Cc4ccncc4)C(=O)[C@H]3C2)s1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CS(=O)(=O)N1CCC2(CC1)CN(CCn1cccn1)C(=O)CO2,CS(=O)(=O)N1CCC2(CC1)CN(CCn1cccn1)C(=O)CO2,CS(=O)(=O)N1CCC2(CC1)CN(CCn1cccn1)C(=O)CO2,CS(=O)(=O)N1CCC2(CC1)CN(CCn1cccn1)C(=O)CO2,CCOCC1CN(C(=O)C2=CCCC2)Cc2cnn(C)c21,CCOCC1CN(C(=O)C2=CCCC2)Cc2cnn(C)c21,O=C(O)C(F)(F)F.O=C([C@H]1C[C@@H]2CCN(c3cccc(F)c3)C[C@H]2O1)N1CCCC1,O=C(O)C(F)(F)F.O=C([C@H]1C[C@@H]2CCN(c3cccc(F)c3)C[C@H]2O1)N1CCCC1,c1cc(-c2nnc([C@H]3CCNC3)o2)ccn1,c1cc(-c2nnc([C@H]3CCNC3)o2)ccn1,CS(=O)(=O)c1ccc(-c2c[nH]c([C@@H]3COCCN3)n2)cc1,CS(=O)(=O)c1ccc(-c2c[nH]c([C@@H]3COCCN3)n2)cc1,COC(=O)c1cccc2nc([C@H]3CCN(Cc4ccccc4)C3)oc12,COC(=O)c1cccc2nc([C@H]3CCN(Cc4ccccc4)C3)oc12,Cc1ccc(CN2CCC3(CC2)C(=O)Nc2ccccc23)s1.O=C(O)C(F)(F)F,Cc1ccc(CN2CCC3(CC2)C(=O)Nc2ccccc23)s1.O=C(O)C(F)(F)F,Cn1cccc1CN1CCc2ncnc(-c3cccnc3)c2CC1,Cn1cccc1CN1CCc2ncnc(-c3cccnc3)c2CC1,CN(C)CCO[C@@H]1CC[C@H]2[C@H]1OCCN2C(=O)c1ccncc1,CN(C)CCO[C@@H]1CC[C@H]2[C@H]1OCCN2C(=O)c1ccncc1,Cc1cncc(C(=O)N2CCO[C@H]3[C@H](OCCN(C)C)CC[C@@H]32)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1cncc(C(=O)N2CCO[C@H]3[C@H](OCCN(C)C)CC[C@@H]32)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1ccc(-n2c(O)cc(C)c(C#N)c2=O)c(C)c1,Cc1ccc(-n2c(O)cc(C)c(C#N)c2=O)c(C)c1,NS(=O)(=O)c1cccnc1Nc1c(Cl)cccc1Cl,NS(=O)(=O)c1cccnc1Nc1c(Cl)cccc1Cl,CN1CCOC[C@H]1c1nc(-c2ccc(F)cc2F)c[nH]1,CN1CCOC[C@H]1c1nc(-c2ccc(F)cc2F)c[nH]1,COc1ccc(-c2nnsc2C(=O)N2CCC(C(N)=O)CC2)cc1,COc1ccc(-c2nnsc2C(=O)N2CCC(C(N)=O)CC2)cc1,Cc1cs/c(=N\C(=O)Cn2nc(N3CCOCC3)ccc2=O)[nH]1,Cc1cs/c(=N\C(=O)Cn2nc(N3CCOCC3)ccc2=O)[nH]1,Cc1ncnc2c1CCN(C(=O)c1ccoc1)CC2,Cc1ncnc2c1CCN(C(=O)c1ccoc1)CC2,COCCNC(=O)c1nc2c(s1)CCCN2c1ccc(C)nn1,COCCNC(=O)c1nc2c(s1)CCCN2c1ccc(C)nn1,Cc1nnc(N2C[C@@H](OCC3CCCC3)[C@H]3OCCC[C@H]32)s1.O=C(O)C(F)(F)F,Cc1nnc(N2C[C@@H](OCC3CCCC3)[C@H]3OCCC[C@H]32)s1.O=C(O)C(F)(F)F,Cc1cccc(CN2C[C@@H](F)[C@@H](OCc3nc4ccccc4[nH]3)C2)n1,Cc1cccc(CN2C[C@@H](F)[C@@H](OCc3nc4ccccc4[nH]3)C2)n1,Cc1ccc2[nH]c(CO[C@H]3CN(c4ccc(C#N)cn4)C[C@H]3F)nc2c1,Cc1ccc2[nH]c(CO[C@H]3CN(c4ccc(C#N)cn4)C[C@H]3F)nc2c1,Cc1ccc2[nH]c(CO[C@H]3CN(c4ccc(C#N)cn4)C[C@H]3F)nc2c1,Cc1ccc2[nH]c(CO[C@H]3CN(c4ccc(C#N)cn4)C[C@H]3F)nc2c1,CC(C)CN1C[C@@H]2OCC(=O)N(c3ccccc3)[C@@H]2C1,CC(C)CN1C[C@@H]2OCC(=O)N(c3ccccc3)[C@@H]2C1,COc1ccc(CN[C@@H]2CO[C@H](CNC(=O)N3CCOCC3)[C@H]2O)cc1,COc1ccc(CN[C@@H]2CO[C@H](CNC(=O)N3CCOCC3)[C@H]2O)cc1,O=C(NCc1ccco1)[C@H]1C[C@@H]2CCN(c3nncs3)C[C@H]2O1.O=C(O)C(F)(F)F,O=C(NCc1ccco1)[C@H]1C[C@@H]2CCN(c3nncs3)C[C@H]2O1.O=C(O)C(F)(F)F,COCCNC(=O)[C@H]1C[C@@H]2CCN(c3ccccc3)C[C@H]2O1.O=C(O)C(F)(F)F,COCCNC(=O)[C@H]1C[C@@H]2CCN(c3ccccc3)C[C@H]2O1.O=C(O)C(F)(F)F,O=C(NCCc1ccncc1)[C@H]1C[C@@H]2CCN(c3nncs3)C[C@H]2O1,O=C(NCCc1ccncc1)[C@H]1C[C@@H]2CCN(c3nncs3)C[C@H]2O1,Cc1cccc(CN2CC3(CCN(C(N)=O)CC3)OCC2=O)n1,Cc1cccc(CN2CC3(CCN(C(N)=O)CC3)OCC2=O)n1,CC(C)(C)CN1CCN2C(=O)N(C3CCCCC3)C[C@H]2C1,CC(C)(C)CN1CCN2C(=O)N(C3CCCCC3)C[C@H]2C1,COC(=O)c1ccc(S(=O)(=O)N2CCC(Oc3cccnn3)CC2)cc1,COC(=O)c1ccc(S(=O)(=O)N2CCC(Oc3cccnn3)CC2)cc1,O=C(O)C1CCN(c2nc3c(-c4ccccc4F)csc3c(=O)[nH]2)CC1,O=C(O)C1CCN(c2nc3c(-c4ccccc4F)csc3c(=O)[nH]2)CC1,Cc1noc([C@@H]2C[C@H](NS(=O)(=O)Cc3ccccc3)CN2C)n1,Cc1noc([C@@H]2C[C@H](NS(=O)(=O)Cc3ccccc3)CN2C)n1,O=C1c2c(O)cc(O)cc2O[C@@H](c2ccc(O)cc2)[C@@H]1O,O=C1c2c(O)cc(O)cc2O[C@@H](c2ccc(O)cc2)[C@@H]1O,COc1cc(O)cc2c1C(=O)CC(c1ccc(O)cc1)O2,COc1cc(O)cc2c1C(=O)CC(c1ccc(O)cc1)O2,CCOCC1CN(Cc2ccoc2)Cc2cn(CC3CC3)nc21,CCOCC1CN(Cc2ccoc2)Cc2cn(CC3CC3)nc21,CCN1CCOCC2(CCCN(C(=O)c3cnccn3)C2)C1,CCN1CCOCC2(CCCN(C(=O)c3cnccn3)C2)C1,CC[C@@H]1N(Cc2cc(OC)cc(OC)c2)CCC[C@]12CCC(=O)N2C,CC[C@@H]1N(Cc2cc(OC)cc(OC)c2)CCC[C@]12CCC(=O)N2C,Cc1ccc(S(=O)(=O)NC[C@H]2OC[C@@H](NCc3cccs3)[C@@H]2O)cc1,Cc1ccc(S(=O)(=O)NC[C@H]2OC[C@@H](NCc3cccs3)[C@@H]2O)cc1,COc1c(-c2ccc(O)cc2)oc2cc(O)cc(O)c2c1=O,COc1c(-c2ccc(O)cc2)oc2cc(O)cc(O)c2c1=O,O=c1c2ccccc2nc2n1CCC2O,O=c1c2ccccc2nc2n1CCC2O |
[INST] Create new Small molecule for target with these components: {'P10408': 'MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ'}; your molecule must be in SMILES format. [/INST]COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,CNc1nc2c(s1)C(c1cc(Cl)ccc1F)CC(=O)N2,CNc1nc2c(s1)C(c1cc(Cl)ccc1F)CC(=O)N2,O=C1CC(c2ccccc2C(F)(F)F)c2sc(N3CCOCC3)nc2N1,O=C1CC(c2ccccc2C(F)(F)F)c2sc(N3CCOCC3)nc2N1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,Nc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,Nc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1Cl)CC(=O)N2,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,O=C1CC(c2ccccc2Br)c2sc(N3CCOCC3)nc2N1,CC(C)Oc1ccccc1C1CC(=O)Nc2nc(N3CCOCC3)sc21,CC(C)Oc1ccccc1C1CC(=O)Nc2nc(N3CCOCC3)sc21,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,CNc1nc2c(s1)C(c1ccc(F)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccc(F)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1cccc(Cl)c1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1cccc(Cl)c1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccc(Cl)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccc(Cl)cc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,CC1(C)OCC(CNC(=O)c2cnn(-c3cc(Cl)ccc3Cl)c2N)O1,CC1(C)OCC(CNC(=O)c2cnn(-c3cc(Cl)ccc3Cl)c2N)O1,CC1(C)OCC(CNC(=O)c2cnn(-c3ccc(Cl)cc3)c2N)O1,CC1(C)OCC(CNC(=O)c2cnn(-c3ccc(Cl)cc3)c2N)O1,COc1ccc(-n2ncc(C(=O)NCC3COC(C)(C)O3)c2N)cc1,COc1ccc(-n2ncc(C(=O)NCC3COC(C)(C)O3)c2N)cc1,COCCNC(=O)c1cn(C(C)(C)C)c2ncccc12,COCCNC(=O)c1cn(C(C)(C)C)c2ncccc12,COCC(C)NC(=O)c1cn(C(C)(C)C)c2ncccc12,COCC(C)NC(=O)c1cn(C(C)(C)C)c2ncccc12,COc1cccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1OC,CNc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1c(F)cccc1Cl)CC(=O)N2,COc1cccc(C2CC(=O)Nc3nc(N)sc32)c1OC,COc1cccc(C2CC(=O)Nc3nc(N)sc32)c1OC,CNc1nc2c(s1)C(c1cccc(F)c1F)CC(=O)N2,CNc1nc2c(s1)C(c1cccc(F)c1F)CC(=O)N2,CNc1nc2c(s1)C(c1c(Cl)cccc1Cl)CC(=O)N2,CNc1nc2c(s1)C(c1c(Cl)cccc1Cl)CC(=O)N2,COCCn1ccc2cc(NC(C)=O)ccc21,COCCn1ccc2cc(NC(C)=O)ccc21,Cc1ccc2c(ccn2CCC(=O)O)c1,Cc1ccc2c(ccn2CCC(=O)O)c1,COCc1c(C(=O)NC2CCCC2)nnn1-c1ccc(C)cc1,COCc1c(C(=O)NC2CCCC2)nnn1-c1ccc(C)cc1,CCCc1c(C(=O)NC2CCCC2)nnn1-c1ccc(OC)cc1,CCCc1c(C(=O)NC2CCCC2)nnn1-c1ccc(OC)cc1,CCn1cc(CN(C)S(=O)(=O)c2cnn(CC)c2C)c(C)n1,CCn1cc(CN(C)S(=O)(=O)c2cnn(CC)c2C)c(C)n1,CCc1c(C(=O)NCC2CCS(=O)(=O)C2)cnn1-c1ccc(C)cc1,CCc1c(C(=O)NCC2CCS(=O)(=O)C2)cnn1-c1ccc(C)cc1,CCNC(=O)Nc1ccc2c(ccn2CC(=O)N(CC)CC)c1,CCNC(=O)Nc1ccc2c(ccn2CC(=O)N(CC)CC)c1 |
[INST] Create new Small molecule for target with these components: {}; your molecule must be in SMILES format. [/INST]NC(=O)c1nc(COc2ccc3c(c2)OCO3)no1,NC(=O)c1nc(COc2ccc3c(c2)OCO3)no1,COc1cccc(C(=O)NCC(O)c2cccs2)c1,COc1cccc(C(=O)NCC(O)c2cccs2)c1,CC(C1CC1)N(C)C(=O)c1cnc(-c2ccc3c(c2)OCO3)s1,CC(C1CC1)N(C)C(=O)c1cnc(-c2ccc3c(c2)OCO3)s1,O=C(CC1CN(Cc2ccccc2)CCO1)Nc1ccccc1F,O=C(CC1CN(Cc2ccccc2)CCO1)Nc1ccccc1F,O=C(Nc1ccc(F)c(Br)c1)N1CCCC1,O=C(Nc1ccc(F)c(Br)c1)N1CCCC1,CC(C)c1cc2c(O)nc(CSCC(=O)O)nc2s1,CC(C)c1cc2c(O)nc(CSCC(=O)O)nc2s1,COc1cccc(-c2nc(C)c(C(=O)NC(CO)CCSC)s2)c1,COc1cccc(-c2nc(C)c(C(=O)NC(CO)CCSC)s2)c1,CC(O)CNCc1ccc(OCc2ccc3c(c2)OCCO3)cc1.Cl,CC(O)CNCc1ccc(OCc2ccc3c(c2)OCCO3)cc1.Cl,Cc1ccc(-c2cc(C(=O)NC(C)C(=O)N3CCCCC3)on2)cc1,Cc1ccc(-c2cc(C(=O)NC(C)C(=O)N3CCCCC3)on2)cc1,Cn1cccc1C(=O)N1CCC2(CC1)CN(c1cncnc1)C(=O)CO2,Cn1cccc1C(=O)N1CCC2(CC1)CN(c1cncnc1)C(=O)CO2,Cc1ccc(N2CC[C@H]3O[C@@H](C(=O)NCc4ccco4)CC[C@H]32)nn1.O=C(O)C(F)(F)F,Cc1ccc(N2CC[C@H]3O[C@@H](C(=O)NCc4ccco4)CC[C@H]32)nn1.O=C(O)C(F)(F)F,O=C(NCCCN1CCOCC1)c1ccn(-c2ccc3ccccn23)n1.O=C(O)C(F)(F)F,O=C(NCCCN1CCOCC1)c1ccn(-c2ccc3ccccn23)n1.O=C(O)C(F)(F)F,CN(C(=O)Cc1ccc(NC(=O)NC2CCC2)cc1)c1ccccc1,CN(C(=O)Cc1ccc(NC(=O)NC2CCC2)cc1)c1ccccc1,Cc1cc(N2CCN(CC(=O)N(C)C)CC2)nc(-c2ccncc2)n1,Cc1cc(N2CCN(CC(=O)N(C)C)CC2)nc(-c2ccncc2)n1,CO[C@@H]1CN(Cc2scnc2C)[C@@H]2CCCO[C@@H]21.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CO[C@@H]1CN(Cc2scnc2C)[C@@H]2CCCO[C@@H]21.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CN1CCc2nc(C3CCN(C(=O)CCC4CCCC4)CC3)ncc2C1,CN1CCc2nc(C3CCN(C(=O)CCC4CCCC4)CC3)ncc2C1,Cc1ccc(NCc2cncc3c2CCN(C(=O)C2CC=CC2)C3)nn1.Cl,Cc1ccc(NCc2cncc3c2CCN(C(=O)C2CC=CC2)C3)nn1.Cl,CCc1nc(COc2ccc(OCc3cnn(C)c3)cc2)no1,CCc1nc(COc2ccc(OCc3cnn(C)c3)cc2)no1,Cc1cc(S(=O)(=O)Nc2cccc(-n3cccc3)c2)sc1C(=O)O,Cc1cc(S(=O)(=O)Nc2cccc(-n3cccc3)c2)sc1C(=O)O,Cc1cnn(CC2CCCN2CC(=O)N(C)Cc2ccc(C)o2)c1,Cc1cnn(CC2CCCN2CC(=O)N(C)Cc2ccc(C)o2)c1,O=C(c1cn(-c2ccccc2Cl)nn1)N1CCCSCC1,O=C(c1cn(-c2ccccc2Cl)nn1)N1CCCSCC1,CNC(=O)c1cnc(/C=C/c2ccc(OC)c(O)c2)s1,CNC(=O)c1cnc(/C=C/c2ccc(OC)c(O)c2)s1,CCCC(NC(=O)c1cc(C)n(C2CC2)c1C)c1nnn[nH]1,CCCC(NC(=O)c1cc(C)n(C2CC2)c1C)c1nnn[nH]1,CC(C)=CCN1C[C@H]2CC[C@@H]1CN(C(=O)c1c[nH]c(=O)c(Cl)c1)C2,CC(C)=CCN1C[C@H]2CC[C@@H]1CN(C(=O)c1c[nH]c(=O)c(Cl)c1)C2,O=C(c1ccc(C2CCCO2)s1)N1Cc2ccccc2C1,O=C(c1ccc(C2CCCO2)s1)N1Cc2ccccc2C1,COCc1noc(-c2ccc(N3CCCCC3CO)nc2)n1,COCc1noc(-c2ccc(N3CCCCC3CO)nc2)n1,CN1CCCC1c1ccc(C(=O)N2CCc3ccccc3C2)s1,CN1CCCC1c1ccc(C(=O)N2CCc3ccccc3C2)s1,Cc1cc(C(=O)N2CCC3(CCCN(CC4CC4)C3=O)C2)c(C)n1C,Cc1cc(C(=O)N2CCC3(CCCN(CC4CC4)C3=O)C2)c(C)n1C,Cl.c1ccc(-c2ccc(C3CNCCO3)nc2)cc1,Cl.c1ccc(-c2ccc(C3CNCCO3)nc2)cc1,COc1cccc(-c2noc(C3CCN(Cc4cccs4)C3)n2)c1.Cl,COc1cccc(-c2noc(C3CCN(Cc4cccs4)C3)n2)c1.Cl,CCc1nc(CN2CCCN(C(=O)CCc3ccco3)CC2)cs1,CCc1nc(CN2CCCN(C(=O)CCc3ccco3)CC2)cs1,c1ccc2sc(N3CCOC(Cn4cccn4)C3)nc2c1,c1ccc2sc(N3CCOC(Cn4cccn4)C3)nc2c1,Cc1nc(CN2CCOC(CNc3cccnn3)C2)oc1C,Cc1nc(CN2CCOC(CNc3cccnn3)C2)oc1C,Cc1ccc(N(C)C2CCN(C(=O)CCc3ccco3)CC2)nn1,Cc1ccc(N(C)C2CCN(C(=O)CCc3ccco3)CC2)nn1,Cc1cnn(CC2CN(c3cnc4ccccc4n3)CCO2)c1,Cc1cnn(CC2CN(c3cnc4ccccc4n3)CCO2)c1,CC(C)c1n[nH]c(C(=O)Nc2cc[nH]n2)c1Br,CC(C)c1n[nH]c(C(=O)Nc2cc[nH]n2)c1Br,Cc1nc(C)c(C(=O)OCCNc2ncccc2C#N)s1,Cc1nc(C)c(C(=O)OCCNc2ncccc2C#N)s1,CN(C)c1cc(CNC(=O)Nc2ccc(F)cc2)ccn1,CN(C)c1cc(CNC(=O)Nc2ccc(F)cc2)ccn1,CNS(=O)(=O)Cc1ccc(CNc2cncc(-n3cccn3)n2)cc1,CNS(=O)(=O)Cc1ccc(CNc2cncc(-n3cccn3)n2)cc1,Cc1cnn(C2CN(CC(=O)NCc3ccccn3)C2)c1,Cc1cnn(C2CN(CC(=O)NCc3ccccn3)C2)c1,Cc1cc(C(C)C(=O)N2CCCN(Cc3cscn3)CC2)c(C)o1,Cc1cc(C(C)C(=O)N2CCCN(Cc3cscn3)CC2)c(C)o1,Cc1noc(NC(=O)c2ccc(OC(F)(F)F)cc2)n1,Cc1noc(NC(=O)c2ccc(OC(F)(F)F)cc2)n1,Cc1ccc(C(=O)Nc2cn[nH]c2)cc1C,Cc1ccc(C(=O)Nc2cn[nH]c2)cc1C,Cc1cc(C(=O)N2CCc3nnc(N)cc3C2)c(C)n1-c1cccnc1,Cc1cc(C(=O)N2CCc3nnc(N)cc3C2)c(C)n1-c1cccnc1,Cc1ccc(-c2nc(CN3CCC(C(=O)N(C)C)CC3)cs2)o1,Cc1ccc(-c2nc(CN3CCC(C(=O)N(C)C)CC3)cs2)o1,Cc1nc(CN2CCCC(N(C)Cc3cscn3)C2)no1,Cc1nc(CN2CCCC(N(C)Cc3cscn3)C2)no1,CCOc1cc(/C=C/c2ncc(C(=O)O)s2)ccc1O,CCOc1cc(/C=C/c2ncc(C(=O)O)s2)ccc1O,CCc1nnc2n1CCN(Cc1csc(-c3ccc(C)o3)n1)C2,CCc1nnc2n1CCN(Cc1csc(-c3ccc(C)o3)n1)C2,COc1cccc(-c2nc(CNCCn3cccn3)cs2)c1,COc1cccc(-c2nc(CNCCn3cccn3)cs2)c1 |
[INST] Create new Small molecule for target with these components: {'P9WPC5': 'MSQVTDMRSNSQGLSLTDSVYERLLSERIIFLGSEVNDEIANRLCAQILLLAAEDASKDISLYINSPGGSISAGMAIYDTMVLAPCDIATYAMGMAASMGEFLLAAGTKGKRYALPHARILMHQPLGGVTGSAADIAIQAEQFAVIKKEMFRLNAEFTGQPIERIEADSDRDRWFTAAEALEYGFVDHIITRAHVNGEAQ', 'P9WPC3': 'MNSQNSQIQPQARYILPSFIEHSSFGVKESNPYNKLFEERIIFLGVQVDDASANDIMAQLLVLESLDPDRDITMYINSPGGGFTSLMAIYDTMQYVRADIQTVCLGQAASAAAVLLAAGTPGKRMALPNARVLIHQPSLSGVIQGQFSDLEIQAAEIERMRTLMETTLARHTGKDAGVIRKDTDRDKILTAEEAKDYGIIDTVLEYRKLSAQTA'}; your molecule must be in SMILES format. [/INST]Cc1ccc(S(=O)(=O)N2CCCC3(CCCN3S(C)(=O)=O)C2)cc1F,CC(C)n1ccc(-c2cc(C(=O)NC3CC3)c3ccccn23)n1,CC(C)n1ccc(-c2cc(C(=O)N3CCN(C)CC3)c3ccccn23)n1.O=C(O)C(F)(F)F,CN1CCCN(C(=O)c2cc(-c3cc[nH]n3)n3ccccc23)CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CCCNC(=O)c1cc(-c2ccn(C(C)C)n2)n2ccccc12,CCNCc1ccc(OCc2ccc3c(c2)OCCO3)cc1.Cl,NC(=O)C1CCN(c2nc3nccc(-c4cccnc4)c3c(=O)[nH]2)CC1,NC(=O)C1CCN(c2nc3nccc(-c4ccncc4)c3c(=O)[nH]2)CC1,COc1ccccc1C1CC(=O)Nc2nc(N3CCCCC3)sc21,CNc1nc2c(s1)C(c1cc(Cl)ccc1F)CC(=O)N2,O=C1CC(c2ccccc2C(F)(F)F)c2sc(N3CCOCC3)nc2N1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c(OC)c1,COc1cc(CN2CCCCCC2c2cccs2)cc(OC)c1O,OCCNc1nc(Nc2ccccc2)c2nccnc2n1,OCCNc1nc(NCCc2ccccc2)nc2nccnc12,Cc1ccc(CN2C[C@@H]3CCN(Cc4ccncc4)C(=O)[C@H]3C2)s1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CC(C)CNc1nc2c(cc1C(=O)NCC1CC1)CCNCC2,CNC(=O)c1cc2c(nc1NC(C)C)CCNCC2,CNC(=O)c1cc2c(nc1NCC1CC1)CCNCC2,COc1cccc(C2CC(=O)Nc3nc(N4CCCCC4)sc32)c1OC,CC(C)Oc1ccccc1C1CC(=O)Nc2nc(N3CCOCC3)sc21,COc1ccc(OC)c(C2CC(=O)Nc3nc(N4CCOCC4)sc32)c1,COc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)sc32)cc1,CNc1nc2c(s1)C(c1ccccc1F)CC(=O)N2,COCCn1cnc(-c2cc(C(=O)NC(C)C)c3ccccn23)c1,CC(C)Nc1nc2c(cc1C(=O)NCC1CC1)CCN(CC1CC1)CC2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CNC(=O)N1CCc2cc(C(=O)NCC3CC3)c(NC(C)C)nc2CC1,CC(C)Nc1nc2c(cc1C(=O)NCC1CC1)CCN(S(C)(=O)=O)CC2.O=C(O)C(F)(F)F,CC(C)Nc1nc2c(cc1C(=O)NCC1CC1)CCN(C)CC2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CNC(=O)c1cc2c(nc1NCC(C)C)CCN(c1ccncn1)CC2.O=C(O)C(F)(F)F,CNC(=O)c1cc2c(nc1NCC1CC1)CCN(CC1CC1)CC2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CCS(=O)(=O)N1CCc2cc(C(=O)NC)c(NCC3CC3)nc2CC1,CN1CCc2c(sc3c2C(=O)NC(/C=C/c2ccccc2)N3)C1,O=C(c1cc(-c2ccn(CC3CC3)n2)n2ccccc12)N1CCOCC1,Cc1nc(-c2cc(C(=O)N3CCCN(C)CC3)c3ccccn23)cn1C.O=C(O)C(F)(F)F,CNC(=O)c1cc2c(nc1NCC1CC1)CCN(S(C)(=O)=O)CC2.O=C(O)C(F)(F)F,OCCNc1nc(NCc2cccnc2)nc2nccnc12,COCCNc1nc(NCCc2ccccc2)nc2nccnc12,CCN1CCc2c(sc3c2C(=O)NC(/C=C\c2ccccc2)N3)C1,COc1ccccc1-c1ccnc2nc(N3CCCCC3)[nH]c(=O)c12,COc1ccc(-c2ccnc3nc(N4CCCC4)[nH]c(=O)c23)cc1OC,COc1cccc(-c2ccnc3nc(N4CCCCC4)[nH]c(=O)c23)c1,Cc1ccc2[nH]c(CO[C@H]3CN(c4ccc(C#N)cn4)C[C@H]3F)nc2c1,O=C(c1c2c(N3CCCC3)ncnc2n2ccccc12)N1CCOCC1,O=C(c1c2c(NCC3CC3)ncnc2n2ccccc12)N1CCCC1,O=C(c1c2c(N3CCOCC3)ncnc2n2ccccc12)N1CCCC1,O=C(c1c2c(NCC3CC3)ncnc2n2ccccc12)N1CCOCC1,O=C(O)C(F)(F)F.O=C(c1ccc2ccccc2n1)N1CCC2(CCN2c2ncccn2)C1,CC(C)Nc1nc2c(c(NC3CC3)n1)CN(C(=O)c1ccsc1)CC2,Cc1ccc(CN2CCC3(C2)C(=O)N(CC2CC2)c2ccccc23)s1.O=C(O)C(F)(F)F,CN(C)c1ncc(-c2cc(C(=O)NC(C)(C)CO)n(CC3CC3)c2)cn1,CN(C)c1ncc(-c2cc(C(=O)N3CCCC3)n(CC3CC3)c2)cn1,N#Cc1ccc(OC[C@]23COC[C@H]2CN(Cc2ccoc2)C3)nc1,CNC(=O)c1cc2c(nc1NCC(C)C)CCN(S(C)(=O)=O)CC2,CNC(=O)c1cc2c(nc1NCC(C)C)CCN(S(=O)(=O)N(C)C)CC2,CNC(=O)c1cc2c(nc1NCC(C)C)CCN(CCOC)CC2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CNC(=O)c1cc2c(nc1NCC(C)C)CCN(C)CC2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,COCCN1CCc2cc(C(=O)NC(C)C)c(NCC(C)C)nc2CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,CCC1(CC)Cc2ccccc2-c2nc(NCCCO)[nH]c(=O)c21,O=c1[nH]c(NCCCO)nc2c1C1(CCCC1)Cc1ccccc1-2,CN1CCc2c(C#N)c(NCc3ccncc3)n3cnnc3c2C1,CNC(=O)c1cc2c(nc1NCC(C)C)CCN(CC1CC1)CC2.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,O=C(O)C(F)(F)F.O=c1ccc2c(n1CC1CCOCC1)CCN(Cc1ccoc1)CC2,COCCNC(=O)c1cc(-c2cc[nH]n2)n2ccccc12.O=C(O)C(F)(F)F,Cc1nc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccn23)cs1.O=C(O)C(F)(F)F,CC/N=c1\nc(NCC)nc2n1C(O)(Nc1cc(Cl)ccc1Cl)CS2,Cn1ccc2c(cnc3nc(-c4ccncc4)nn32)c1=O,COCCN1CCc2cc(C(=O)NC(C)C)c(NCC3CC3)nc2CC1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F,Cc1ccc(CN2C[C@@H]3[C@@H](C(=O)N4CCCC4)CCS(=O)(=O)[C@@H]3C2)cc1.O=C(O)C(F)(F)F,O=C(NCCCO)c1cc(-c2cc[nH]n2)n2ccccc12.O=C(O)C(F)(F)F,CC(C)(CO)CNC(=O)c1cc(-c2cc[nH]n2)n2ccccc12.O=C(O)C(F)(F)F,CCc1ccc(S(=O)(=O)N2CCCC3(CCCN3S(C)(=O)=O)C2)cc1,COCCn1cnc(-c2nc(C(=O)N3CCOCC3)c3ccccn23)c1,Cc1nc(-c2nc(C(=O)N3CCOCC3)c3ccccn23)cn1C(C)C,CC(C)n1cnc(-c2nc(C(=O)N3CCN(C)CC3)c3ccccn23)c1,CC(C)n1cnc(-c2nc(C(=O)N3CCCC3)c3ccccn23)c1,COC(=O)CNC(=O)c1cn(-c2ccccn2)c(=O)c2ccccc12,CC(C)CNC(=O)c1cn(-c2ccccn2)c(=O)c2ccccc12,O=C(O)c1cn(-c2ccccn2)c(=O)c2ccccc12,CN1C(=O)c2cccc(NC(=O)c3ccc4c(c3)OCCO4)c2C1=O,Cc1cc(C)n(-c2ccc3nnc(C)n3n2)n1,Cc1nc2oc(C(=O)N3CCOCC3)c(N)c2c2c1CCCC2,CC(C)c1nc2oc(C(=O)N3CCOCC3)c(N)c2c2c1CCCC2,COc1ccc2c(c1)C(=O)CC1(CCN(Cc3ccc(F)cc3)CC1)O2,CN(C)C(=O)CN1CCC2(CC1)CC(=O)c1ccc3ccccc3c1O2,NC(=O)CN1CCC2(CC1)CC(=O)c1ccc3ccccc3c1O2,CCOC(=O)CN1CCC2(CC1)CC(=O)c1ccc3ccccc3c1O2,Cc1nc(NC(=O)CN2C(=O)c3ccccc3NC2C(C)C)sc1C,COCc1nnc(NC(=O)CN2C(=O)c3ccccc3NC2C(C)C)s1,CC(C)C1Nc2ccccc2C(=O)N1CC(=O)Nc1nc2c(s1)CCC2,CC(C)c1nnc(NC(=O)CN2C(=O)c3ccccc3NC2C(C)C)s1,CN(C)S(=O)(=O)c1ccc(-c2nc(C#N)c(NC(C)(C)C)o2)o1.Cl,CN(C)S(=O)(=O)c1ccc(-c2nc(C#N)c(NC3CCCCC3)o2)o1,CC(C)Nc1oc(-c2ccc(S(=O)(=O)N(C)C)o2)nc1C#N,CN(C)S(=O)(=O)c1ccc(-c2nc(C#N)c(NC3CC3)o2)o1,CNc1oc(-c2ccc(S(=O)(=O)N(C)C)o2)nc1C#N,COC(=O)c1cc(OC)ccc1NCC(=O)NCC(=O)N1CCCC1,N#Cc1cccnc1N1CCC(OCc2ccccc2)CC1,CC(CN1CCCC1=O)NC(=O)c1ccc(-c2ccco2)[nH]c1=O,CCNC(=O)C1CCCN(c2ccc3ccc(F)cc3n2)C1 |
[INST] Create new Small molecule for target with these components: {'P09385': 'MKCILFKWVLCLLLGFSSVSYSREFTIDFSTQQSYVSSLNSIRTEISTPLEHISQGTTSVSVINHTPPGSYFAVDIRGLDVYQARFDHLRLIIEQNNLYVAGFVNTATNTFYRFSDFTHISVPGVTTVSMTTDSSYTTLQRVAALERSGMQISRHSLVSSYLALMEFSGNTMTRDASRAVLRFVTVTAEALRFRQIQREFRQALSETAPVYTMTPGDVDLTLNWGRISNVLPEYRGEDGVRVGRISFNNISAILGTVAVILNCHHQGARSVRAVNEESQPECQITGDRPVIKINNTLWESNTAAAFLNRKSQFLYTTGK', 'P09386': 'MKKMFMAVLFALASVNAMAADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSGFAEVQFNND'}; your molecule must be in SMILES format. [/INST]CC1(C)OCC(CNC(=O)c2cnn(-c3ccc(Cl)cc3)c2N)O1,CC1(C)OCC(CNC(=O)c2cnn(-c3ccc(Cl)cc3)c2N)O1,Cc1cc(-c2nn(C)c(Cl)c2CN2Cc3ccccc3C(O)C2)no1,Cc1cc(-c2nn(C)c(Cl)c2CN2Cc3ccccc3C(O)C2)no1,O=C(Cc1cccc(Cl)c1)N[C@@H]1CCNC[C@H]1O,O=C(Cc1cccc(Cl)c1)N[C@@H]1CCNC[C@H]1O,CC(C)c1cc(C(F)(F)F)n2nc(CCC(=O)O)nc2n1,CC(C)c1cc(C(F)(F)F)n2nc(CCC(=O)O)nc2n1,CN(C)S(=O)(=O)N1CCCC(c2cccc(Cc3ccccc3)n2)C1,CN(C)S(=O)(=O)N1CCCC(c2cccc(Cc3ccccc3)n2)C1,O=S(=O)(c1ccccc1)N1CCCCC1c1cc[nH]n1,O=S(=O)(c1ccccc1)N1CCCCC1c1cc[nH]n1,Cc1nc(C(=O)N2CCC(Cc3cnc4[nH]ccc4c3)C2)co1,Cc1nc(C(=O)N2CCC(Cc3cnc4[nH]ccc4c3)C2)co1,NCc1cn(-c2ccccc2C(=O)NCc2cccc(Cl)c2)cn1,NCc1cn(-c2ccccc2C(=O)NCc2cccc(Cl)c2)cn1,Cc1cc(-c2cnn(CCNC(=O)C3CC3)c2C2CC2)on1,Cc1cc(-c2cnn(CCNC(=O)C3CC3)c2C2CC2)on1,CCOc1ccccc1C(=O)N1CCCC1c1ncc2c(n1)CCNC2.Cl,CCOc1ccccc1C(=O)N1CCCC1c1ncc2c(n1)CCNC2.Cl,O=C1CN(Cc2ccc(-c3ccccc3C(=O)O)cc2)CCN1,O=C1CN(Cc2ccc(-c3ccccc3C(=O)O)cc2)CCN1,Cn1cc(C(=O)N2CCC(Cc3nccs3)CC2)cn1,Cn1cc(C(=O)N2CCC(Cc3nccs3)CC2)cn1,Nc1cc(CCC2CN(Cc3ccc(C(=O)O)cc3)CCO2)ccn1,Nc1cc(CCC2CN(Cc3ccc(C(=O)O)cc3)CCO2)ccn1,COc1ncc(C2(O)CCN(Cc3c(F)cccc3F)CC2)c(OC)n1.Cl,COc1ncc(C2(O)CCN(Cc3c(F)cccc3F)CC2)c(OC)n1.Cl,COc1ccccc1CC(=O)N1CC[C@@]2(CCCO2)[C@@H](OC)C1,COc1ccccc1CC(=O)N1CC[C@@]2(CCCO2)[C@@H](OC)C1,Cc1nccn1-c1cccc(C2CCCN2S(=O)(=O)c2cn(C)cn2)n1,Cc1nccn1-c1cccc(C2CCCN2S(=O)(=O)c2cn(C)cn2)n1,CCOC(=O)c1sc2ccsc2c1CN.Cl,CCOC(=O)c1sc2ccsc2c1CN.Cl,COCCN1CCN(CCS(=O)(=O)C(F)(F)F)CC1C,COCCN1CCN(CCS(=O)(=O)C(F)(F)F)CC1C,CC(C)(C)NC(=O)NC(=O)CNC(C)(C)c1ccc2c(c1)OCCO2,CC(C)(C)NC(=O)NC(=O)CNC(C)(C)c1ccc2c(c1)OCCO2,COc1ccc(C)cc1CN(C)Cc1nc2c(cnn2C)c(=O)[nH]1,COc1ccc(C)cc1CN(C)Cc1nc2c(cnn2C)c(=O)[nH]1,CCOc1ccnc(N2CCN(C(=O)c3cccc(C#N)c3)CC2)n1,CCOc1ccnc(N2CCN(C(=O)c3cccc(C#N)c3)CC2)n1,Cc1noc(NC(=O)c2ccc(OC(F)(F)F)cc2)n1,Cc1noc(NC(=O)c2ccc(OC(F)(F)F)cc2)n1,Cc1noc(NC(=O)c2ccc(Br)cc2)n1,Cc1noc(NC(=O)c2ccc(Br)cc2)n1,Cc1noc(NC(=O)c2ccc(Br)s2)n1,Cc1noc(NC(=O)c2ccc(Br)s2)n1,N#Cc1ccc(NCCNc2ccc(C(F)(F)F)cn2)nc1,N#Cc1ccc(NCCNc2ccc(C(F)(F)F)cn2)nc1,O=S(=O)(CCN1CCOC(Cn2cccn2)C1)C(F)(F)F,O=S(=O)(CCN1CCOC(Cn2cccn2)C1)C(F)(F)F,COc1c(CNC(c2ccc(F)cc2)C(C)(C)C)c(C)nn1C,COc1c(CNC(c2ccc(F)cc2)C(C)(C)C)c(C)nn1C,CN(Cc1ccsc1)C(=O)CS(=O)(=O)Cc1ccc(Cl)c(Cl)c1,CN(Cc1ccsc1)C(=O)CS(=O)(=O)Cc1ccc(Cl)c(Cl)c1 |
[INST] Create new Small molecule for target with these components: {'P0DTC2': 'MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT'}; your molecule must be in SMILES format. [/INST]COc1c2c3c4c(c(OC)c(=O)c5c(O)cc(OC)c(c6c(OC)cc(O)c(c1=O)c63)c54)[C@@H](C(C)=O)[C@@](C)(O)C2,CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12,Oc1c(I)cc(Cl)c2cccnc12,Cc1cc(O)c2c(c1)C(=O)c1cc(O)cc(O)c1C2=O,O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,COc1ccc(S(=O)(=O)O)cc1/N=N/c1c(S(=O)(=O)O)cc2cc(Nc3nc(Nc4ccccc4)nc(Nc4cc(C)c(/N=N/c5cc(S(=O)(=O)O)cc6cc(S(=O)(=O)O)cc(O)c56)cc4OC)n3)ccc2c1O,CCOC(=O)c1c(CSc2ccccc2)n(C)c2cc(Br)c(O)c(CN(C)C)c12 |
[INST] Create new Small molecule for target with these components: {'P0DTC2': 'MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT'}; your molecule must be in SMILES format. [/INST]COc1c2c3c4c(c(OC)c(=O)c5c(O)cc(OC)c(c6c(OC)cc(O)c(c1=O)c63)c54)[C@@H](C(C)=O)[C@@](C)(O)C2,CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12,Oc1c(I)cc(Cl)c2cccnc12,Cc1cc(O)c2c(c1)C(=O)c1cc(O)cc(O)c1C2=O,O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,COc1ccc(S(=O)(=O)O)cc1/N=N/c1c(S(=O)(=O)O)cc2cc(Nc3nc(Nc4ccccc4)nc(Nc4cc(C)c(/N=N/c5cc(S(=O)(=O)O)cc6cc(S(=O)(=O)O)cc(O)c56)cc4OC)n3)ccc2c1O,CCOC(=O)c1c(CSc2ccccc2)n(C)c2cc(Br)c(O)c(CN(C)C)c12,COc1c(O)c2c(=O)cc(OC)c3c4c(OC)cc(=O)c5c(O)c(OC)c6c(c(c1C[C@](C)(O)[C@H]6C(C)=O)c23)c54,COC1=C(CC(C)=O)C(=O)c2c(c(O)cc(OC)c2-c2c(OC)cc(O)c3c2C(=O)C(CC(C)=O)=C(OC)C3=O)C1=O |
[INST] Create new Small molecule for target with these components: {'P0DTC2': 'MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT'}; your molecule must be in SMILES format. [/INST]COc1c2c3c4c(c(OC)c(=O)c5c(O)cc(OC)c(c6c(OC)cc(O)c(c1=O)c63)c54)[C@@H](C(C)=O)[C@@](C)(O)C2,CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12,Oc1c(I)cc(Cl)c2cccnc12,Cc1cc(O)c2c(c1)C(=O)c1cc(O)cc(O)c1C2=O,O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12,COc1ccc(S(=O)(=O)O)cc1/N=N/c1c(S(=O)(=O)O)cc2cc(Nc3nc(Nc4ccccc4)nc(Nc4cc(C)c(/N=N/c5cc(S(=O)(=O)O)cc6cc(S(=O)(=O)O)cc(O)c56)cc4OC)n3)ccc2c1O,CCOC(=O)c1c(CSc2ccccc2)n(C)c2cc(Br)c(O)c(CN(C)C)c12,COc1c(O)c2c(=O)cc(OC)c3c4c(OC)cc(=O)c5c(O)c(OC)c6c(c(c1C[C@](C)(O)[C@H]6C(C)=O)c23)c54,COC1=C(CC(C)=O)C(=O)c2c(c(O)cc(OC)c2-c2c(OC)cc(O)c3c2C(=O)C(CC(C)=O)=C(OC)C3=O)C1=O,CCCCCCCCO[C@H]1O[C@@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H](O[C@@H]3O[C@@H](C)[C@@H](O[C@@H]4O[C@@H](C)[C@@H](OS(=O)(=O)[O-])[C@@H](OS(=O)(=O)[O-])[C@@H]4OS(=O)(=O)[O-])[C@@H](OS(=O)(=O)[O-])[C@@H]3OS(=O)(=O)[O-])[C@@H](OS(=O)(=O)[O-])[C@@H]2OS(=O)(=O)[O-])[C@@H](OS(=O)(=O)[O-])[C@@H]1OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+],O=C(OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1O)c1cc(O)c(O)c(O)c1,CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)[C@@H](C)O |
[INST] Create new None for target with these components: {'Q92793': 'MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL', 'P35222': 'MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL'}; your molecule must be in SMILES format. [/INST]C[C@H]1[C@H]2N(C(=O)CN(C)N2C(=O)NCc2ccccc2)[C@@H](Cc2ccc(OP(=O)(O)O)cc2)C(=O)N1Cc1cccc2cccnc12 |
[INST] Create new Unknown for target with these components: {'O14791': 'MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL'}; your molecule must be in SMILES format. [/INST]O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@@H]1C(=O)NC[C@@H]1O,N#Cc1ccc(-c2[nH]c3c(F)cc(F)cc3c2CCC(=O)N[C@H]2CCNC2=O)cc1,N#Cc1cc(F)cc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccc(F)cc3)[nH]c12,O=C(CCc1c(-c2ccccc2)[nH]c2c(F)cccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2cc(F)c(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,COc1ccc(-c2[nH]c3ccccc3c2CCC(=O)N[C@@H]2C(=O)NC[C@H]2O)cc1,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@@H]1C(=O)NC[C@@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1CCNC1=O,CC(=O)O[C@@H]1CNC(=O)[C@H]1NC(=O)CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,O=C1C[C@H](NC(=O)CCc2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc23)C(=O)N1,CC1C[C@H](NC(=O)CCc2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc23)C(=O)N1,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1C[C@@H](CO)NC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1C[C@H](CO)NC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1C[C@@H](CF)NC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1C[C@H](CF)NC1=O,C[C@H]1CNC(=O)[C@H]1NC(=O)CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1C(=O)NC[C@@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@@H]1CCNC1=O,CC1(NC(=O)CCc2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc23)CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1C(=O)NC[C@H]1O,O=C1C[C@@H](NC(=O)CCc2c(-c3ccc(F)cc3)[nH]c3c(F)cc(F)cc23)C(=O)N1,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)NC1CC2(CC2)NC1=O,N#Cc1ccc(-c2[nH]c3c(F)cc(F)cc3c2CCC(=O)N[C@H]2CCNC2=O)cc1,O=C(CCc1c(-c2ccc(OC(F)F)cc2)[nH]c2c(F)cc(F)cc12)N[C@H]1CCNC1=O,Cc1ccc(-c2[nH]c3c(F)cc(F)cc3c2CCC(=O)N[C@@H]2C(=O)NC[C@H]2O)cc1,Cc1ccc(-c2[nH]c3c(F)cc(F)cc3c2CCC(=O)N[C@H]2CCNC2=O)cc1,Cc1ccc(-c2[nH]c3c(F)cc(F)cc3c2CCC(=O)N[C@@H]2CCNC2=O)cc1,O=C(CCc1c(-c2ccccc2)[nH]c2c(F)cc(F)cc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccccc2)[nH]c2c(F)cc(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(Br)cc12)N[C@H]1CCNC1=O,N#Cc1cc(F)c2[nH]c(-c3ccc(F)cc3)c(CCC(=O)N[C@H]3CCNC3=O)c2c1,Cc1cc(F)c2[nH]c(-c3ccc(F)cc3)c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c2c1,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(Cl)cc12)N[C@@H]1C(=O)NC[C@H]1O,Cc1cc(F)c2[nH]c(-c3ccc(F)cc3)c(CCC(=O)N[C@H]3CCNC3=O)c2c1,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(Cl)cc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(Cl)cc12)N[C@@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(Cl)cc(F)cc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccccc2)[nH]c2c(Cl)cc(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(Cl)cc(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,Cc1cc(F)cc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccc(F)cc3)[nH]c12,Cc1cc(F)cc2c(CCC(=O)N[C@H]3CCNC3=O)c(-c3ccc(F)cc3)[nH]c12,COc1cc(F)cc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccc(F)cc3)[nH]c12,COc1cc(F)cc2c(CCC(=O)N[C@H]3CCNC3=O)c(-c3ccc(F)cc3)[nH]c12,N#Cc1cc(F)cc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccc(F)cc3)[nH]c12,Cc1ccc2[nH]c(-c3ccc(Br)cc3)c(CCC(=O)N[C@H]3CCNC3=O)c2c1,O=C(CCc1c(-c2ccccc2)[nH]c2ccc(Cl)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(Cl)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(F)cc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(F)cc12)NC1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(F)cc12)N[C@@H]1CCNC1=O,CN(C(=O)CCc1c(-c2ccc(F)cc2)[nH]c2ccc(F)cc12)C1CCNC1=O,O=C(CCc1c(-c2ccccc2)[nH]c2ccc(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2ccc(F)cc12)N[C@H]1CCNC1=O,N#Cc1cccc(-c2[nH]c3ccc(F)cc3c2CCC(=O)N[C@H]2CCNC2=O)c1,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(OCc3ccccc3)cc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(O)cc12)N[C@H]1CCNC1=O,COc1ccc2[nH]c(-c3ccc(F)cc3)c(CCC(=O)N[C@H]3CCNC3=O)c2c1,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)c(F)ccc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)c(F)ccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2c(F)c(F)ccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2c(F)cccc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccccc2)[nH]c2c(F)cccc12)N[C@@H]1C(=O)NC[C@H]1O,C=Cc1cccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccccc3)[nH]c12,O=C(CCc1c(-c2ccccc2)[nH]c2c(C3CC3)cccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2c(C3=CCOC3)cccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2c(C3CCOC3)cccc12)N[C@@H]1C(=O)NC[C@H]1O,CC(C)(O)c1cccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccccc3)[nH]c12,C=C(C)c1cccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccccc3)[nH]c12,CC(C)c1cccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccccc3)[nH]c12,Cc1cccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccccc3)[nH]c12,O=C(CCc1c(-c2ccccc2)[nH]c2c(Br)cccc12)N[C@@H]1C(=O)NC[C@H]1O,Cc1cccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccc(F)cc3)[nH]c12,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(Cl)cccc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(Cl)cccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2c(Cl)cccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cccc12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)cccc12)N[C@@H]1C(=O)NC[C@H]1O,COc1cccc2c(CCC(=O)N[C@H]3CCNC3=O)c(-c3ccc(F)cc3)[nH]c12,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)ccc(F)c12)N[C@H]1CCNC1=O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2c(F)c(F)c(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2c(F)c(F)c(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2cc(F)c(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2cc(F)c(F)cc12)N[C@@H]1C(=O)NC[C@H]1O,Cc1c(F)ccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccc(F)cc3)[nH]c12,Cc1c(F)ccc2c(CCC(=O)N[C@@H]3C(=O)NC[C@H]3O)c(-c3ccccc3)[nH]c12,O=C(CCc1c(-c2ccccc2)[nH]c2cc(F)cc(F)c12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccccc2)[nH]c2ccccc12)N[C@@H]1C(=O)NC[C@H]1O,O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccccc12)N[C@@H]1C(=O)NC[C@H]1O,[2H]C([2H])(C(=O)N[C@@H]1C(=O)NC[C@H]1O)C([2H])([2H])c1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,[2H]C(C(=O)N[C@@H]1C(=O)NC[C@H]1O)C([2H])c1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,C[C@@H](Cc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)C(=O)N[C@H]1CCNC1=O,C[C@@H](Cc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12)C(=O)N[C@@H]1C(=O)NC[C@H]1O,O=C(N[C@@H]1C(=O)NC[C@H]1O)[C@H](O)Cc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,O=C(N[C@H]1CCNC1=O)[C@H](O)Cc1c(-c2ccccc2)[nH]c2c(F)cc(F)cc12,O=C1NC[C@@H](O)[C@@H]1NC(=O)[C@@H](O)Cc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,O=C1NC[C@@H](O)[C@@H]1NC(=O)C(F)(F)Cc1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,CC(CC(=O)N[C@H]1CCNC1=O)c1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12,CC(CC(=O)N[C@@H]1C(=O)NC[C@H]1O)c1c(-c2ccc(F)cc2)[nH]c2c(F)cc(F)cc12 |
[INST] Create new Unknown for target with these components: {'O60488': 'MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK'}; your molecule must be in SMILES format. [/INST]Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,O=C(O)c1ccc(Oc2ccc3oc4ccccc4c(=O)c3c2)cc1,O=C(O)C[C@H]1CC[C@@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=C(O)C[C@H]1CC[C@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=C(O)CCCCCCOc1ccc2oc3ccccc3c(=O)c2c1 |
[INST] Create new Unknown for target with these components: {'O60488': 'MKLKLNVLTIILLPVHLLITIYSALIFIPWYFLTNAKKKNAMAKRIKAKPTSDKPGSPYRSVTHFDSLAVIDIPGADTLDKLFDHAVSKFGKKDSLGTREILSEENEMQPNGKVFKKLILGNYKWMNYLEVNRRVNNFGSGLTALGLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYATLGKEAVVHGLNESEASYLITSVELLESKLKTALLDISCVKHIIYVDNKAINKAEYPEGFEIHSMQSVEELGSNPENLGIPPSRPTPSDMAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVLELTAEISCFTYGCRIGYSSPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPEIMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLSGGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDYTTGRVGAPLICCEIKLKDWQEGGYTINDKPNPRGEIVIGGQNISMGYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGCLQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSYVISFVVPNQKRLTLLAQQKGVEGTWVDICNNPAMEAEILKEIREAANAMKLERFEIPIKVRLSPEPWTPETGLVTDAFKLKRKELRNHYLKDIERMYGGK'}; your molecule must be in SMILES format. [/INST]Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,O=C(O)c1ccc(Oc2ccc3oc4ccccc4c(=O)c3c2)cc1,O=C(O)C[C@H]1CC[C@@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=C(O)C[C@H]1CC[C@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=C(O)CCCCCCOc1ccc2oc3ccccc3c(=O)c2c1,O=C(O)CCCCOc1ccc2oc3ccccc3c(=O)c2c1 |
[INST] Create new Unknown for target with these components: {'O95573': 'MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPVNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK'}; your molecule must be in SMILES format. [/INST]Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,O=C(O)c1ccc(Oc2ccc3oc4ccccc4c(=O)c3c2)cc1,O=C(O)C[C@H]1CC[C@@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=C(O)C[C@H]1CC[C@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=C(O)CCCCCCOc1ccc2oc3ccccc3c(=O)c2c1 |
[INST] Create new Unknown for target with these components: {'O95573': 'MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPVNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK'}; your molecule must be in SMILES format. [/INST]Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,O=C(O)c1ccc(Oc2ccc3oc4ccccc4c(=O)c3c2)cc1,O=C(O)C[C@H]1CC[C@@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=C(O)C[C@H]1CC[C@H](Oc2ccc3oc4ccccc4c(=O)c3c2)CC1,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(OC[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@@H](C(=O)O)CC3)cc12,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@H](C(=O)O)CC3)cc12,O=C(O)CCCCCCOc1ccc2oc3ccccc3c(=O)c2c1,O=C(O)CCCCOc1ccc2oc3ccccc3c(=O)c2c1 |
[INST] Create new Unknown for target with these components: {'P17302': 'MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI'}; your molecule must be in SMILES format. [/INST]COc1ccc(COC[C@H]2O[C@H](O[C@@H]3[C@@H](O)[C@H](O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](N)C[C@H]3N)[C@H](O)[C@@H](N)[C@@H]2OCc2ccc(OC)cc2)cc1,Cc1ccc(COC[C@H]2O[C@H](O[C@@H]3[C@@H](O)[C@H](O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](N)C[C@H]3N)[C@H](O)[C@@H](N)[C@@H]2OCc2ccc(C)cc2)cc1,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4ccc(Cl)cc4)[C@@H](OCc4ccc(Cl)cc4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4ccc(F)cc4)[C@@H](OCc4ccc(F)cc4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4ccc5ccccc5c4)[C@@H](OCc4ccc5ccccc5c4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4cccc(-c5ccccc5)c4)[C@@H](OCc4cccc(-c5ccccc5)c4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,Cc1ccc(OC[C@H]2O[C@H](O[C@@H]3[C@@H](O)[C@H](O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](N)C[C@H]3N)[C@H](O)[C@@H](N)[C@@H]2O)cc1,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COc4ccc(Cl)cc4)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COc4ccc(-c5nc6ccccc6[nH]5)cc4)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,N[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CNC(=O)c4ccccc4-c4c5ccc(=O)cc-5oc5cc(O)ccc45)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2N)O[C@H](CO)[C@H]1O,N[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CNC(=O)CCCc4cc5ccc6cccc7ccc(c4)c5c67)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2N)O[C@H](CO)[C@H]1O |
[INST] Create new Unknown for target with these components: {'P17302': 'MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGKSDPYHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI'}; your molecule must be in SMILES format. [/INST]COc1ccc(COC[C@H]2O[C@H](O[C@@H]3[C@@H](O)[C@H](O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](N)C[C@H]3N)[C@H](O)[C@@H](N)[C@@H]2OCc2ccc(OC)cc2)cc1,Cc1ccc(COC[C@H]2O[C@H](O[C@@H]3[C@@H](O)[C@H](O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](N)C[C@H]3N)[C@H](O)[C@@H](N)[C@@H]2OCc2ccc(C)cc2)cc1,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4ccc(Cl)cc4)[C@@H](OCc4ccc(Cl)cc4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4ccc(F)cc4)[C@@H](OCc4ccc(F)cc4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4ccc5ccccc5c4)[C@@H](OCc4ccc5ccccc5c4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COCc4cccc(-c5ccccc5)c4)[C@@H](OCc4cccc(-c5ccccc5)c4)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,Cc1ccc(OC[C@H]2O[C@H](O[C@@H]3[C@@H](O)[C@H](O[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](N)C[C@H]3N)[C@H](O)[C@@H](N)[C@@H]2O)cc1,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COc4ccc(Cl)cc4)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](COc4ccc(-c5nc6ccccc6[nH]5)cc4)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O,N[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CNC(=O)c4ccccc4-c4c5ccc(=O)cc-5oc5cc(O)ccc45)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2N)O[C@H](CO)[C@H]1O,N[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CNC(=O)CCCc4cc5ccc6cccc7ccc(c4)c5c67)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2N)O[C@H](CO)[C@H]1O,NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O |
[INST] Create new Unknown for target with these components: {'P41216': 'MEVHELFRYFRMPELIDIRQYVRTLPTNTLMGFGAFAALTTFWYATRPKALKPPCDLSMQSVEIAGTTDGIRRSAVLEDDKLLVYYYDDVRTMYDGFQRGIQVSNNGPCLGSRKPNQPYEWISYKEVAELAECIGSGLIQKGFKPCSEQFIGLFSQNRPEWVIVEQGCFSYSMVVVPLYDTLGADAITYIVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYGSDLVERGKKCGVEIISLKALEDLGRVNRVKPKPPEPEDLAIICFTSGTTGNPKGAMITHQNIINDCSGFIKATESAFIASTDDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNRMFDRIFGQANTSLKRWLLDFASKRKEAELRSGIVRNNSLWDKLIFHKIQSSLGGKVRLMITGAAPVSATVLTFLRTALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYVKLVDVEEMNYLASKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDRKKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFVHGESLQAFLIAVVVPDVESLPSWAQKRGLQGSFEELCRNKDINKAILDDLLKLGKEAGLKPFEQVKGIAVHPELFSIDNGLLTPTLKAKRPELRNYFRSQIDELYATIKI'}; your molecule must be in SMILES format. [/INST]Cn1c(Cc2ccc3c(c2)OCC3)nc2cc(O[C@H]3CC[C@@](F)(c4nnn[nH]4)CC3)ccc21,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@](F)(c5nnn[nH]5)CC4)ccc3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](c5noc(=O)[nH]5)CC4)ccc3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](c5nnn[nH]5)CC4)ccc3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(N)=O)CC4)ccc3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ncc3n2C)c1,Cc1cccc(Cc2nc3nc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(Cc2nc3c(Cl)c(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)c(Cl)cc3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)cc(Cl)c3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C(C)C)c1,Cc1cccc(COc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(C(=O)c2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(Oc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cn1c(Cc2ccc3c(c2)OCC3)nc2cc(O[C@H]3CC[C@@H](C(=O)O)CC3)ccc21,Cn1c(Cc2cccnc2)nc2cc(O[C@H]3CC[C@@H](C(=O)O)CC3)ccc21,Cn1c(Cc2cccc(C#N)c2)nc2cc(O[C@H]3CC[C@@H](C(=O)O)CC3)ccc21,Cn1c(Cc2cccc(C(F)(F)F)c2)nc2cc(O[C@H]3CC[C@@H](C(=O)O)CC3)ccc21,Cc1ccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)cc1,Cc1ccccc1Cc1nc2cc(O[C@H]3CC[C@@H](C(=O)O)CC3)ccc2n1C,Cc1cccc(Cc2nc3ccc(O[C@H]4CC[C@@H](C(=O)O)CC4)cc3n2C)c1,Cc1cccc(Cc2c(C#N)c3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(Cc2c(C(N)=O)c3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(Cc2cc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(Cn2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3c2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3n2C)c1,Cc1cccc(Cc2nc3cc(O[C@H]4CC[C@@H](C(=O)O)CC4)ccc3o2)c1,O=C(O)[C@H]1CC[C@@H](Oc2ccc3oc(-c4ccccc4)nc3c2)CC1,O=C(O)[C@H]1CC[C@@H](Oc2ccc3c(c2)Cc2ccccc2O3)CC1,O=c1c2ccccc2oc2ccc(O[C@H]3CC[C@H](C(=O)O)CC3)cc12 |
[INST] Create new Unknown for target with these components: {'P43118': 'MSINSSKQPASSAAGLIANTTCQTENRLSVFFSIIFMTVGIVSNSLAIAILMKAYQRFRRKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSVFGISMVFSGLCPLFLGSTMAIERCIGVTNPLFHSTKITSKHVKMILSGVCMFAVFVALLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSSLGLLALGISFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMVIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKENQQASSEAGL'}; your molecule must be in SMILES format. [/INST]Cc1c(N2CCCC2)nc2ccc(Br)cc2c1C(=O)NC[C@H](CCC(=O)O)c1ccccc1Cl,Cc1c(N2CCCC2)nc2ccc(Br)cc2c1C(=O)NC[C@H](CCC(=O)O)c1ccccc1Cl |