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Research Data Analyst . Computational biologist in the Gawad lab , in the Hematology Oncology division of Pediatrics Analyzing , interpreting , and visualizing DNA data to advance precision medicine Building data pipelines in Stanford 's HPC cluster with Perl , Python , R , Bash , and open source software for automated , high throughput analysis of genetic data . . Technologies : | null |
Senior Research Associate . Senior Research Associate Novozymes Department : ASAP Assay , Screening Protostabilization ERAD Enzymes Research Automation and Digitalization Automating and digitalizing workflows Cross functional learning cycles between Wild Type , PE and production strains across Enzyme Research Molecular biologic methods , including MTP Cloning , enzymes digesting , PCR , genomic DNA , spore PCR , DNA sequence Nanopore , transformation in E coli and in Bacillus subtilis , Bacillus licheniformis and Aspergillus oryzae Robot and machine learning , primer and cloning design for automation Assays and expression of enzymes Liquid handler ; Tecan , Agilent s BRAVO and laboratory robot Data processing in Jupyter Notebook Python , Excel and JMP Protein engineering and optimizing enzyme variants Cloning and transformation in Aspergillus oryzae Primer and cloning design for automation in Jupyter Notebook HTP assay screening HTP Screening on laboratory robots for enzyme activity and stability in Bacillus subtilis and Aspergillus oryzae Small scall fermentation in MTP Laboratory robots , Momentum and Agilent 's BRAVO Data processing in Jupyter Notebook Python , Excel and JMP . I have strong knowledge , experience and hands on in molecular biology , Protein engineering PE and microbiology including techniques such as qPCR , ddPCR , DNA sequencing NGS , Nanopore , Sanger , cloning , genomic RNA and DNA , assay , purification , gene editing , CRISPR , assay , expression of different enzymes for activity , small scale fermentation and data processing , robot and machine learning , primer and cloning design for automation . I have been working in eukaryotic and prokaryotic organisms Laboratory robots and liquid handlers , such as : Tecan , Agilent 's Bravo , Biomek and Hamilton . Languages Fluent in Danish and English , both in verbal and written .. Technologies : | enzymes;expression;stability |
Vice chair of QSP Special Interest Group . . Dr. Lourdes Cucurull Sanchez leads the Quantitative and Systems Pharmacology strategy in GSK Clinical Development , with the goal to embed QSP into its MIDD framework . During her prior Discovery Research experience , she provided programmes with mechanistic QSP simulations to help them accelerate or gain confidence in their path forward . She has set up mechanisms to develop and promote the QSP discipline within and outside GSK . Elected Vice chair of the ISoP QSP SIG . Founder and active member of the UK QSP Network . Member of the IQ Consortium QSP WG2 , ASCPT and ISoP. Prior to joining GSK , she accrued 8 years of modelling experience at Pfizer , firstly as a Computational Chemist and later on as a QSP modeller . She has influenced decisions concerning a wide range of indications , mechanisms and therapeutic modalities , across the therapeutic areas of oncology , immuno inflammation , respiratory , neurosciences , gastrointestinal and genitourinary . In 2022 she received a GSK Innovation , Performance and Trust IPTc award for her impactful performance . In 2007 she received a Pfizer W.E. Upjohn Award for her outstanding contributions and accomplishments in the area of Innovation . In 2004 , she was appointed as Postdoctoral Research Associate at the University of Cambridge , sponsored by Unilever . She obtained her PhD in Chemistry in 2000 at the Universitat Autonoma de Barcelona . In 1995 she obtained an MPhil in Chemistry at The University of Newcastle upon Tyne , sponsored by The British Council and La Caixa . Specialties : Quantitative Systems Pharmacology , MID3 , Systems Biology , PKPD modelling , Machine Learning , Mathematical Modelling , Modelling and Simulations , In silico ADME , Computational Chemistry , Strategic Thinking , Management , Networking , Influencing , Diversity Inclusion .. Technologies : | null |
Computational Staff Scientist Engineer . . . Technologies : | null |
User Engagement Lead Community Manager . Work at the intersection between research scientists and the KBase development and implementation teams to ensure that KBase can help answer important questions regarding microbes and society . . Making science more efficient by helping to improve microbiome data science through effective communication and collaboration . I work across the science , technology , engineering , and communications space with the goal of accelerating our understanding of microbes in our environment and health . My professional training is in marine science , with a foundation in using ' omics to understand biological interactions , and I am passionate about making science communication and collaboration impactful . . Technologies : | null |
Ph . D . Projects focussing on structural and biochemical characterization of various families of membrane proteins . . . Technologies : | membrane proteins;characterization;structure |
Researcher . . Mariano studied biology at Universidad de Buenos Aires , Argentina , where he also obtained his PhD in chemical biology with Gonzalo Prat Gay . He was a post doc in the group of Cathy Royer in Montpellier , and a post doc at the Structural Virology , Felix Rey 's lab in Paris , before he started his lab in Buenos Aires . His main interest is currently in the understanding of membrane protein protein interactions using biochemistry , biophysics and high resolution cryo EM structure determination .. Technologies : CryoEM | membrane proteins;interaction;structure |
Senior Scientist , Assoc . Professor . Senior scientist at Therapeutic Immune Design Unit , Dept of Clin . Neuroscience , Karolinska Institutet Assoc professor in molecular immunology . Research profile : Allergen specific immunotherapy , immune regulation in allergy and inflammation , immune regulation in neuroinflammatory disease , vaccine adjuvant development , cancer immunotherapy , clinical trials Research , supervision of students , teaching , scientific writing . Role at present positions : Senior researcher and Assoc . Professor at Karolinska Institutet at Dept . of Clinical Neuroscience , Therapeutic Immune design unit . Research area : Cancer immunotherapy , allergy and multiple sclerosis . Disease mechanisms in terms of regulation of the immune response to allergens autoantigens and inflammation . Cancer immunotherapy development for clinical application . Preparation for clinical Phase I II clinical trial of personalized cell therapy of cancer . CTO at TCER AB , member of management team and of the board . Responsible for cell therapy R D , clinical trial preparation and project coordination . Previous positions : Director of Immunolgy , Viscogel AB . Responsibility for the company 's immunology program focused on vaccine adjuvant development . Chief coordinator of a project within the EU FP7 program research for SMEs under grant agreement no 261954 : ViVac ViscoGel , a chitosan based adjuvant for prophylactic and therapeutic vaccination , coordinated by Viscogel AB 2010 2012 . The project included a clinical phase I IIa clinical trial . Senior scientist and associate professor at Dept of Medicine , Karolinska Institutet . Research on allergens , mechanisms of allergy and asthma and novel strategies for allergy vaccination . Postdoc project : Basic research on membrane protein assembly using molecular biology techniques . PhD in medical biochemistry : PhD thesis title : Isolation and characterization of variant forms of secretin and vasoactive intestinal peptide with special emphasis on their biosynthesis Summary of skills : Methodological : allergy and asthma models in mice , preclinical and clinical research studies . Immunology , cell biology , molecular biology and biochemistry techniques . Project leading ; Research leadership , organisation of scientific meetings and seminars , research funding applications for EU grants and national grants . Research and project presentations , oral and written . Clinical trial experience from a phase I IIa clinical trial at Viscogel AB . Member of the local human ethics committee in Stockholm . Technologies : | null |
Graduate Student . Structural Biology RNA Research Lab Graduate Research Assistant , University of Michigan Co mentored by Dr. Amanda Garner and Dr. Melanie Ohi Thesis title : Structure and functional analysis of Human Dicer . Research Interests Cryo Electron Microscopy Structure and function analysis of RNA binding proteins MicroRNA biogenesis RNA structure Data Visualization . Technologies : CryoEM | nucleic acids;proteins;interaction;structure |
Bioinformatician . Working on HIV cure strategies in children . . Technologies : | null |
Science leader in Computational Toxicology . . . Technologies : | null |
Head NanoImaging Core Facility . Head of the NanoImaging Core Facility and available as consultant for cryo EM application training , help with picking the right hardware lab setup , help in dealing with companies . Experienced Senior Manager with a demonstrated history of working in the research industry and academia . Skilled in Electron and Light Microscopy in all its facets , Teaching and Education , Research and Development R D , Marketing and Sales , Applications , Chemistry , Materials Science and Soft Matter , Physics , and Life Sciences . Strong professional with a long standing industrial career at FEI Thermofisher and experienced in working with the pharmaceutical industry . Also a significant academic career at the Radboud University Nijmegen , Eindhoven University of Technology , The Dutch Cancer Institut and Institut Pasteur . Strong communicator and presenter with an extensive international network . Deep financial insight in small medium and large sized companies as well as universities and research institutions . Experienced in sales and marketing strategy techniques like Miller Heiman and STRAP procedures . Well accustomed to quarterly targets and deliverables , but also accustomed to longer term academic planning . Able to communicate in 4 languages and available as consultant for trainings , R D , marketing , sales , strategic advice for M A or investments as well as setting up labs and purchasing equipment especially focussed on cryo electron microscopy . . Technologies : CryoEM | structure |
Senior Scientist . . A computational chemist with 6 years of industry experience in drug discovery . One of the inventors for 7 patent applications , and 2 pre clinical candidates . Experienced in hit identification , knowledge based drug design optimization in collaboration with cross functional teams .. Technologies : | null |
Lead Scientist . . I work on machine learning research at Booz Allen Hamilton with applications in adversarial defense , privacy , and cyber . I am also involved with biostatistics , genomics , and computational epidemiology research at Stanford and Harvard Universities . Currently I am also pursuing a part time PhD in CS ML at UMBC .. Technologies : | null |
Doctoral Researcher . Tanishq joined the Levenson lab in August 2019 : Research on applying deep learning to novel microscopy techniques for enabling digital pathology applications . First author of book chapter in Artificial Intelligence and Deep Learning in Pathology Mentored computer science senior design team 4th yr undergrad students working on lab project Mentored two other undergraduate students working on a variety of lab projects Presented PhD research at ICML2020 Computational Biology workshop , BMES 2020 , SPIE Photonics Europe 2022 One first author journal publication under review One first author journal publication under preparation . Tanishq Abraham is recognized as a child genius and a prodigy . He graduated high school at 10 years old with a 4.0 GPA and at 11 he obtained 3 college Associate Degrees also with a perfect 4.0 GPA . When he was 14 , he finished his biomedical engineering program . He graduated from University of California , Davis with summa cum laude becoming the youngest biomedical engineer . As an undergrad , he has presented papers at several conferences . At 14 , he was the first author on a review paper about smart bio inspired vesicles and it 's biomedical engineering applications published in IOP Physical Biology . Tanishq joined the biomedical engineering PhD program at 15 . By 16 , he became a published book chapter author in the book Artificial Intelligence and Deep Learning in Pathology . Now at 19 , he is a 5th year PhD candidate in biomedical engineering at UC Davis . He has worked for 3 years in the Levenson Lab at UC Davis on applying deep learning to novel microscopy techniques in order to enable digital pathology applications . He has presented his PhD research at various venues , such as the ICML2020 Computational Biology workshop and SPIE Photonics Europe . Tanishq has also reviewed few books that includes two science fiction books and recently a machine learning book . Tanishq is self motivated , curious about the mechanics of things , a passionate learner , goal setter and achieving those goals , a hard worker and an over achiever . He enjoys all things science , technology , politics , movies and sports . Loves to interact and talk with people . Tanishq has appeared on many international and national TV , radio and print news , TV and radio talk shows , realty TV shows and documentary shows . He is a role model for young and old students . Technologies : | null |
CNRS Researcher . . My aim is to understand glycosyltransferases and glycan modifying enzymes on a molecular level by combining structural biology approaches with in vitro and in vivo functional analyses . After carrying out a PhD 2013 2016 in the group of Michael Hothorn , first at the Max Planck Institute in T bingen Germany and then at University of Geneva Switzerland , I joined the group of Kaspar Locher at ETH Z rich Switzerland as a postdoctoral fellow to study the yeast oligosaccharyltransferase complex using cryo electron microscopy . In 2019 , I was recruited by the CNRS as Charg de Recherche de Classe Normale and in the following year I obtained the ATIP Avenir grant . I am now leading a small team focusing on the characterization of the heparan sulfate biosynthesis machinery in the SAGAG group at the Institut de Biologie Structurale in Grenoble . . Technologies : CryoEM | enzymes;structure |
Director Bioinformatics and Data Analytics . . Experienced Bioinformatician with a demonstrated history of working in pharmaceuticals industry . Skilled in Life Sciences , NGS data analysis , precision medicine , R and Algorithms . Strong research professional with a PhD focused in Bioinformatics from Technische Universit t Dresden . . Technologies : | null |
CNRS researcher DR2 , Deputy Director of CiTCoM , Team leader Membrane transport signaling . bacterial resistance to antibiotics RND efflux transporters , regulators , b lactamases , porines Integrated structural biology : crystallography , cryo EM , SAXS Biophysical analyses of bio molecules interactions . Expertise : structural biology of membrane proteins MP and of large assembly complexes using crystallography ; production and crystallization of MPs extracted from either membrane of gram negative bacteria ; development of crystallization tools specific to MPs sponge phase ; model of protein actors in antibiotic resistance ; structure function analysis of eukaryotic bitopic receptors ProlactinR , VEGFR The projects of my team focus on tripartite efflux pumps from Pseudomonas aeruginosa implicated in antibiotic resistance . Our recent work , linking in cellulo MIC measurements , crystallography and cryo electron microscopy , brought important information for the comprehension of the assembly mechanism of these pumps . Technologies : CryoEM | membrane proteins;interaction;structure |
Post Doc at Purdue University . . My interests are : Macromolecular structure and dynamics . Multi protein complexes and conformational changes . Virus Antibody structures and structural virology . Viral conformational changes . Transmembrane singling . Cryo Electron Microscopy and tomography . . Technologies : CryoEM | proteins;structure |
Group Leader Screening Sciences . . My current focus are enabling innovative drug discovery technologies and novel drug modalities in the interface of chemistry and biology . We are scouting , evaluating and deploying emerging methods and technologies to identify novel first in class drug mechanisms and prototypes . Besides a number of innovative drug discovery approaches our focus is on two encoded library technologies : DNA encoded chemical libraries DEL and ribosomal in vitro display of cyclic peptide libraries containing non natural amino acids Peptide Discovery . Our group uses both technologies to identify novel starting points in pharmaceutical drug discovery projects . Since 2000 , I am involved in early stage pharmaceutical drug discovery research at the Novartis Institutes for Biomedical Research . I started as Labhead in the Lead Finding Platform with responsibility for the development , and realization of highly miniaturized and automated high throughput hit finding projects to identify new drug candidates . From 2007 to 2012 , I was leading the Label Free Technologies group in the Center for Proteomic Chemistry . 2012 I had the opportunity to build and lead the Screening Sciences Group . Since 2018 , I am the Basel lead of our Chemical Genetics group within the Chemical Biology Therapeutics . I received my Ph . D. in Bioorganic Chemistry at the Max Planck Institute of Biochemistry in Martinsried in 1999 and studied Chemistry at the Ludwig Maximilians Universitaet in Munich , Germany . From 1999 to 2000 , I worked as a post doctorate in the Combinatorial Chemistry department at Novartis Research on the multiparallel combinatorial synthesis of radio tag encoded chemical libraries . . Technologies : | peptides;small molecules;screening |
Scientific Researcher . Researcher working with electron cryo microscopy Cryo EM at Stockholm University studying the evolution of the mitochondrial ribosome . . . Technologies : CryoEM | structure |
Bioinformatics Scientist . . As a member of DRAGEN structural variant team at Illumina , I work on developing , implementing , and benchmarking statistical and machine learning methods together with a focus on algorithms and high performance computing to provide accurate and feasible analysis of NGS data .. Technologies : | null |
Release and Stability coordinator senior associate scientist . planning and coordinating all QC activities deliverables related to product release according to feasible project timelines lead times , including label pack samples and start stability studies . The Quality Control Development QCD labs group is part of the Analytical Development AD Department of the Vaccines Process and Analytical Development VPAD sector . It consists of 6 sub teams Raw Materials , Sample Management , Cell Culture , Microbiology , Release Stability and Data Systems and is responsible for release and stability R S testing as well as the corresponding reporting of Janssen s virus and antibody products for use in clinical trials and the analytical support of the pilot plant activities . . . Technologies : | antibodies;developing;quality;stability |
Undergraduate Researcher . Working on analyzing metabolomics and metagenomics data to bring out insights on the relationship of microbiomes and human health . . Harvey Mudd graduate and computational biologist in training . Interested in using machine learning , statistical , and probabilistic approach to tackle problems in multi omics , microbial ecology , and cancer genomics . Here 's my Google Scholar page : https : scholar.google.com citations view op list works hl en hl en user djX0gYMAAAAJ . Technologies : | null |
Lead Biologist Project Manager . Project manager of the TEAD inhibitor program in licensed in May 2021 . Lead multiple small molecule drug discovery programs from initial project review to LO together with the Med Chem team in different therapeutic areas oncology , MS , HD . Identify , design perform innovative drug screening technologies to determine compounds activity : full screening cascade , target engagement , PK PD translation elucidation MoA. Management of all world wide CRO based activities , from optimal CRO identification , contracting , to weekly team meetings . Oversee all internal lab based activities in support of the projects on a day to day basis . Manage follow up scientific non scientific aspects of projects : patent literature , grant reports , timelines , publications budgeting . Develop broad knowledge of the competitive intelligence horizon for each project . Report on progress of projects to internal teams , management , licensing opportunities , scientific advisory board partners involved . I am a creative , autonomous and proactive project leader with over 8 years of experience in biotech leading multiple drug discovery projects from initiation to Lead Optimization and in licensing . I have learned to work with great detail , under high pressure and under tight deadlines , and this while keeping my enthusiastic attitude . I have proven that I can adapt to very diverse fields of expertise . . Technologies : | small molecules;interaction;screening |
Senior Scientist . HTS biology discovery . Protein Biochemist Biophysicist with 5 years experience in Biotech and drug discovery Accomplished , multifaceted and energetic Ph.D. scientist with demonstrated hands on experience implementing protein biochemistry and biophysical methodologies to study difficult protein targets . Demonstrated success in developing and implementing novel biophysical methodologies for drug discovery Versatile and adaptable biophysicist implementing various techniques to assays hard to drug targets Goal oriented , organized leader conceiving , designing and executing projects Areas of Expertise : Drug discovery HTS screening Hit to lead assay development Soluble and Membrane Protein Expression and Purification Protein Quality Control Analysis PAGE , SEC , chromatography , CD , dynamic static Light Scattering , Mass Spec . , Chemical Cross linking , Thermal DenaturationAssays , DSF Protein engineering and construct rational design Protein labeling and conjugation Small Molecules substrates , inhibitors , ligands binding and mechanism of action Membrane protein crystallography specialty lipids , bicelles , LCP Effective communication skills Efficient Project and time Management to meet goals on marked time frames Innovation Team leadership Creative problem solving Collaborative and Synergistic across various disciplines . Technologies : SLS DLS;DSF | membrane proteins;proteins;small molecules;expression;quality;screening;stability |
Lead Scientist , Respiratory R D . Lead , manage , plan , and monitor all aspects of formulation R D activities from early feasibility to commercial manufacture . Plan and develop novel initiatives to produce successful formulations for drug device combination products . Work as a member of cross functional pharmaceutical project teams providing technical support across a range of processes and equipment trains and troubleshoot any associated development issues . Evaluate , manage , and lead interactions with third parties to achieve project goals . . Provide Technical leadership to other team members . Deliver high levels of customer service both internal external . . Expertise : Oral Solids Nanopharmaceuticals NDA ANDA Paediatric Inhalation Drug Development . Experienced pharmaceutical scientist with more than 9 years of experience in all aspects of NDA and ANDA product development including oral solids , liquids , nanoparticles , lipid based formulations , novel paediatric platforms and scale up through launch for regulated markets . Strong educational credentials including a PhD in Pharmaceutics . Skilled in designing experiments to support product development within a team based environment ; interacting with customers to address product development needs and tailor formulations accordingly . Demonstrated expertise in managing direct reports and also mentoring and sharing knowledge with colleagues at all levels . Exceptional ability to concurrently manage several projects from R D scale to commercial production , while at the same time meeting aggressive timelines . Research expertise also includes the development of novel drug delivery systems , such as nanoparticles , liposomes , proliposomes , and controlled modified release systems . Expertise in addressing solubility and bioavailability related challenges as well as performing in vivo mapping of formulations . Excellent interpersonal and communication skills with the experience required to remain highly focused and exceptionally productive in a fast paced , high pressure environment . Highly flexible individual ability to switch seamlessly from one project to another when priorities change . . Technologies : | formulation |
Senior Scientist . . Experienced Researcher with a demonstrated history of interdisciplinary collaborations within the biotechnology industry . Expertise in Protein Chemistry , Structural Biology , Biophysics , Membrane Proteins , Protein Lipid Interactions , Enzyme Kinetics , RNA Biochemistry , and Protein Purification . . Technologies : | membrane proteins;nucleic acids;proteins;characterization;interaction;structure |
Senior Scientist Bioanalytics . . Studied Biochemical engineering and researched membrane protein biophysics with a keen interest in process , product , and analytics development . Bringing broad range of knowledge to specialized Outside in problem solving .. Technologies : | membrane proteins;characterization |
Sr . Scientist Data Architecture . At Capsida Biotherapeutics , Scott is building and delivering solutions with innovative pipelines and scientific workflows across the organization from basic research to process and analytics development . This data science team is leading the adoption and growth of cutting edge computational biology and engineering tools in the context of an exciting gene therapy biotech start up . . I started my career as a bench scientist in a molecular biology lab at the Salk Institute for five years . I was always drawn to software based tools and how well they enabled and enhanced many aspects of science . Following that interest , I acquired a Master degree in computer science before joining Amgen in 1998 where I was able to merge the two disciplines software and computation to support and facilitate cutting edge scientific research . At Amgen , I worked as a software developer , lead programmer , business analyst , product owner , project manager , technical lead , systems architect , cloud architect , and client facing lead for numerous areas and projects in Research Informatics .. Technologies : | null |
Graduate Research Assistant . Method 1 : Development of antibody conjugated affinity based TEM grid which can selectively capture tau filament from Alzheimer type neurodegenerative diseases and prion disease patient brain tissue for structure determination . My current two high potential projects involves High Resolution Three Dimensional Structure Determination of Helical Filament from three human neurodegenerative patient 's brain using Cryo EM : a Tau Filaments from Two Prion Diseases GSS and PrP CAA Adopt Same Folding as Alzheimer s Disease Manuscript under review b Cryo EM structure determination of Tau filament from frontotemporal Dementia Patient Brain Work in progress c Purifying Human Tau Filament from Different variant of Frontotemporal Dementia patient 's Brain for structural analysis using Cryo EM Structure Analysis On going Method 2 : Development of Inhibitor Modified TEM Grid Fabrication Technique for Rare Human Protein Purification in Single Step for Cryo EM Analysis . 3.6 Angstrom Resolution Structure of Target Protein Achieved Accepted in ACS Nano . Method 3 : Development Polymer Based Materials for Concentrating Pure Engineered and Non engineered Biomolecules on TEM Grid Surface for Cryo EM Analysis Manuscript in preparation . Method 4 : A pseudovirus nanoparticle vaccine targeting the receptor binding HA1 domains of influenza viruses : This work has developed S60 HA1 pseudovirus nanoparticles into an effective flu vaccine targeting the receptor binding domains of influenza viruses Manuscript Under Review in ACS Nano . Structural Biology Cryo EM Membrane Protein Human Prion Diseases Human Neurodegenerative Diseases Prion protein amyloidoses Frontotemporal Dementia Gerstmann Str ussler Sheinker GSS Prion Protein cerebral amyloid angiopathy PrP CAA Tau Filament Organic Synthesis Google Scholar : https : rb.gy k2fviq . Technologies : CryoEM | antibodies;idps;structure |
Senior Scientist . . Specialties : Cryo electron tomography . Technologies : CryoEM | null |
Scientist . . Ph.D. specializing in microscopy , genomics and computer vision . Proven expertise in developing computer vision algorithms for quantitative inference of biological processes such as cancer progression and stem cell engineering .. Technologies : | null |
Research Scientist . . Specialties : X ray crystallography , Membrane proteins , Protein biochemistry , Construct design , Protein expression , Protein purification and Crystallization . Technologies : Xray | membrane proteins;expression;structure |
Principal Scientist I Bioinformatics . . Working on algorithm development of modules in oncology pipelines . . Technologies : | null |
Doktorand . Ribosome targeting antibiotics and antibiotic resistance mechanisms , translational stalling and regulation of translation . Biochemistry , molecular biology and structural biology Cryo electron microscopy . Supervisor : Prof. Dr. Daniel N. Wilson . . . Technologies : CryoEM | proteins;interaction;structure |
PHD Candidate . Neurovascular Interface group . Fast track student . International Max Planck Research School for Neural Circuits . Currently employing single cell and spatial transcriptomics approaches to study vascular diversity in CNS development . Managing high resolution cryo electron microscopy projects to visualize native endothelial cell structures . . PhD student specialized in brain and vascular biology . Experienced in establishing novel experimental , microscopy imaging and analysis pipelines for solving biological questions . My interests align with strategizing complex projects for scientific discovery and technological development . I enjoy presenting my results using story telling and data visualization tools and it is my favorite part of the PhD experience .. Technologies : CryoEM | null |
Visiting Scientist . . . Technologies : | null |
Associate Director of AMRF Functional Genomics Common Research Resource . . I am running a bioinformatic core for Adelson Medical Research Foundation where we have a large number of world class collaborators inside and outside of UCLA . I have extensive experience in both wet lab and computational biology . I am an author of 50 peer reviewed publications and have an expertise in the following fields : Single cell bulk RNAseq ATACseq , DNA microarray , Methylation Seq , miRNAseq , ChIPseq , Proteomics , Membrane Protein Biochemistry , Liquid Chromatography Mass Spectrometry , Bioinformatics , Database Management , Retinol Physiology , Angiogenesis , Cancer Biology and Neuroscience . I am enjoying computational analysis of large datasets in genomics and proteomics , but I also enjoy communicating with my client daily basis and listen to their requests and provide better experimental designs , insights in biology and analysis methods , ultimately lead to high profile journal publications . I also maintain public website for Bioinformatic tools and tutorials . Please visit : https : trello.com b 3g0Twoa7 bioinformatics training resources geschwind lab . Technologies : | null |
Research Assistant . . 8 years of professional experience in Life Sciences panning diverse streams like Pharmaceuticals , Nutraceuticals , Biologics , Diagnostics . Hands on experience in PROTAC PROteolysis TArgeting Chimera Assays Classical Drug Discovery Electrophysiology Manual Automated Patch Clamp Assay Design Development Cell Based Assays Ion Channels , GPCRs , Calcium and Thallium Flux assays Toxicity Profiling hERG Kv 11.1 Channel inhibitors Screening Activity Screens EC50 IC50 Determination Multipelxing Flow Cytometry and Magnetic bead based Multi analyte determination Immunophenotyping Determination of various cell populations Physiologically Relevant in vitro model Development , Primary Culture DRG neurons , Splenocytes and Lymphoctes Isolation , PBMC Cultures Stable cell line generation Single cell cloning Biochemical Assays ELISA , TR FRET , Absorbance based Assays Affinity Assays Radioactive Ligand Binding in vitro Permeability Assays Determination of Gastric permeability , Bioaccessibility , Blood Brain Barrier permeabilty Activity profiling of Nutraceuticals PDCAAS Scoring SOFT SKILLS Technical Write up , Technology Transfer , Proposal writing , Troubleshooting , Report generation . Client Communication , Client Management . Technologies : FRET | molecular glues;small molecules;developing;screening |
Scientist II . . An innovative scientist with extensive experience in in vitro cell biology to help drive target validation for novel drug biotherapeutic development programs , including fifteen years of gene delivery protein expression large scale cell culture in Sf9 insect cells , HEK 293 CHO primarily of GPCRs , stem cell research , assay development and optimization of novel technologies from fast paced biotech pharmaceutical setting to rigorous and regulated chemical industry standards Most recently , two years in academic research overseeing a young and vibrant genetics lab s daily operation supporting graduate and postdoctoral projects while maintaining an independent scholastic endeavor , plus two years in Cellular and Molecular Toxicology for one of the leading chemical companies developing , validating and implementing in vitro cell based assays to determine cellular and molecular mechanism of toxic action utilizing primary cells and established cell lines via flow cytometry , qRT PCR gene expression studies , luminescence , fluorescence , and absorbance based reporter technologies within a GLP laboratory setting A seasoned flow cytometrist , certified operator of Beckman Coulter flow cytometers Epics XL MCL , Gallios utilizing Expo 32 ADC software as well as Becton Dickinson flow cytometers FACSAria II SORP sorter utilizing FACSDiva software , FACScan , Guava An empathetic team leader and a resourceful team player with excellent interpersonal skills and the passion to pursue excellence in the workplace . Technologies : | null |
Doctoral Student . AG Becker Supervisor : Prof. Becker . Doctoral Student at the Institute for Virology of the Philipp University of Marburg 1 . Studies on homo oligomerization of Ebola Virus VP30 and development of an interaction inhibitor 2 . Development of targeted Protein degradation via PROTACs as antiviral therapy against Ebola Virus and SARS CoV 2 . 3 . Studies on Rab1 dependent intracellular trafficking of SARS CoV 2 spike protein . Technologies : | molecular glues;proteins;small molecules;interaction |
Bioinformatics Scientist II . . . Technologies : | null |
Bioinformatics Research Scientist . . . Technologies : | null |
Director Of Bioinformatics . . . Technologies : | null |