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NCT02554786 | 12:33:chronic_disease,45:51:chronic_disease,84:88:chronic_disease,90:101:chronic_disease,103:128:chronic_disease,130:145:chronic_disease,170:184:chronic_disease,189:208:chronic_disease | history of chronic lung diseases other than asthma, including (but not limited to) COPD, sarcoidosis, interstitial lung disease, cystic fibrosis, clinically significant bronchiectasis and active tuberculosis | {
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NCT02501954 | 74:90:cancer | Patients with FIGO 2009 surgical Stage I or II endometrial clear cell or serous carcinoma and with positive peritoneal cytology | {
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NCT01829958 | 14:31:chronic_disease | Uncontrolled diabetes mellitus | {
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NCT02075047 | 18:25:chronic_disease | Imminent risk of suicide or homicide | {
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NCT02945293 | 1:17:chronic_disease | anxiety disorder requiring regular medication | {
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NCT02843646 | 1:8:chronic_disease | Seizure history interfering with use of functional electrical stimulation as verified by their MD | {
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NCT01877382 | 32:59:treatment,95:103:chronic_disease | Has unresolved toxicities from previous anticancer therapy, defined as toxicities (other than alopecia) not yet resolved to NCI-CTCAE v4 | {
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NCT00857207 | 34:45:treatment,87:102:treatment,104:111:treatment,113:128:treatment,133:147:treatment | Changes within the past month of medications known to affect cognitive functions e.g. benzodiazepines, opioids, antidepressants and antipsychotics | {
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NCT01758042 | 26:29:chronic_disease,31:34:chronic_disease,39:44:chronic_disease | Serologic positivity for HIV, HCV, or HbsAg positivity | {
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NCT00670358 | 1:19:chronic_disease | Cardiac arrhythmia | {
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NCT01530958 | 1:25:chronic_disease, | severe visual impairment preventing use of a touch-tone telephone keypad | {
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NCT03115463 | 22:53:chronic_disease | Prenatally diagnosed congenital diaphragmatic hernia | {
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NCT02811510 | ,35:43:treatment | At least one lifetime exposure to cannabis | {
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NCT02579265 | 1:14:chronic_disease | Gastroschisis | {
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NCT02991144 | ,,115:129:chronic_disease,145:154:treatment,156:167:treatment,172:189:treatment | with documented diagnosis of late onset (defined as first manifestation of signs and symptoms at ≥1 month of age) OTC deficiency, confirmed via enzymatic, biochemical, or molecular testing | {
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NCT02389309 | 66:77:cancer,132:144:cancer,164:182:cancer,187:207:cancer | Patients must have had a previous histological verification of a solid tumor at the original diagnosis and/or recurrence including brain tumors; for patients with brain stem gliomas and optic pathway tumors, the requirement for histological evaluation may be waived | {
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NCT02991677 | 1:24:chronic_disease | Coronary artery disease | {
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NCT03159936 | 66:74:treatment | Concomitant use of moderate to potent inhibitors and inducers of CYP3A4/5 | {
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NCT03060473 | 11:37:chronic_disease | any other active bacterial infection | {
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NCT02366871 | 1:28:chronic_disease | systemic lupus erythematous | {
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NCT01925131 | ,,80:97:treatment | at least >= 20% of those blasts must be CD22-positive (surface) based on local immunophenotyping and histopathology | {
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NCT02582827 | 12:38:chronic_disease,60:87:chronic_disease,89:144:treatment | History of inflammatory bowel disease (active or past), or active peptic ulcer disease (prophylaxis with H2 blockers and proton pump inhibitors is acceptable) | {
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NCT02520791 | 1:20:cancer,, | Follicular lymphoma grade 1, 2 or 3A that meets the following criteria | {
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NCT01045148 | 1:27:cancer | Stage < T1b, T2c, T3 or T4 disease (AJCC 6th Edition, see Appendix II) | {
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NCT01568918 | 1:30:treatment | Cervical Posterior Discectomy | {
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NCT01989585 | 14:65:chronic_disease | A history of glucose-6-phosphate dehydrogenase (G6PD) deficiency | {
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NCT02527265 | 10:18:chronic_disease,,68:80:chronic_disease,117:124:cancer,126:130:chronic_disease,135:156:chronic_disease,232:244:chronic_disease,263:276:chronic_disease, | Unstable diabetes control, defined as 2 or more episodes of severe hypoglycemia (i.e., an episode associated with a seizure, coma, or loss of consciousness) or any hospitalization or emergency room visit for poor diabetes control, ketoacidosis, hypoglycemia, or hyperglycemia within the preceding 3 months from screening | {
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NCT02393157 | 1:44:chronic_disease | Uncontrolled hepatitis B and/or C infection | {
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NCT02519322 | 15:24:cancer,26:33:cancer,35:40:cancer,42:47:cancer,52:77:cancer | patients with cutaneous, mucosal, acral, ocular or unknown primary melanomas are eligible for enrollment | {
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NCT01994382 | 10:22:cancer,, | Previous malignancies within 2 yrs. unless relapse risk is small (< 5%) | {
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NCT01919619 | 1:22:chronic_disease, | myocardial infarction within 6 months of study entry | {
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NCT02076906 | 1:30:treatment | Myelosuppressive chemotherapy | {
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NCT02391987 | 23:32:allergy_name,34:46:allergy_name,48:56:allergy_name,58:65:allergy_name | Known skin allergy to adhesives (hydrocolloid, silicone, acrylic) | {
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NCT02310464 | 1:23:treatment | Chemotherapeutic Agent | {
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NCT02342327 | 18:49:chronic_disease | current unstable medical / psychiatric condition | {
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NCT01653093 | 7:29:chronic_disease | known circulatory impairment | {
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NCT02688569 | 1:9:chronic_disease | Insomnia complaints for 6+ months | {
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NCT02579044 | 21:31:treatment | currently receiving lonafarnib under protocol 09-06-0298 | {
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NCT01993719 | ,,74:84:treatment | Absolute neutrophil count greater than 1000/mm(3) without the support of filgrastim | {
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NCT01696734 | ,46:77:treatment | not post-menopausal for 12 months or without previous surgical sterilization | {
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NCT00737893 | 1:22:chronic_disease | myocardial infarction | {
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NCT02020707 | 1:19:chronic_disease,54:88:chronic_disease,122:144:treatment | Immuno-compromised patients and patients known to be human immunodeficiency virus (HIV) positive and currently receiving antiretroviral therapy | {
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NCT02390752 | 15:23:cancer,34:49:treatment,34:48:treatment,53:64:treatment,141:145:chronic_disease,,244:251:treatment | Patients with leukemia receiving corticosteroids or hydroxyurea are eligible provided that the corticosteroids are not being used to manage GVHD and there has been no increase in corticosteroid of hydroxyurea dose for 7 days prior to starting PLX3397 | {
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NCT02864862 | 46:66:treatment | The reasons for extraction will include poor endodontic prognosis | {
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NCT02437110 | 71:81:treatment | competent caregiver who can and will be responsible for administering study drug | {
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NCT02561104 | 91:102:treatment | Poor dilating pupil such that the iris is not peripheral to the intended diameter for the capsulotomy | {
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NCT01970176 | 13:33:treatment, | Received an investigational drug within 1 month prior to dosing | {
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NCT02446886 | 34:51:chronic_disease | Patients with a known history of diabetes mellitus | {
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NCT02193490 | 12:19:chronic_disease, | Documented Dry Eye Disease for at least 6 months | {
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NCT01815359 | 25:34:cancer | Subjects with classical carcinoid | {
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NCT02595866 | 54:78:treatment | Grade 3 or 4 immune related toxicity associated with prior ipilimumab therapy that has not resolved to grade 0 or 1 | {
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NCT02148796 | 37:57:chronic_disease,64:106:chronic_disease,110:125:chronic_disease | Participants may not have any other chronic lung disease; e.g. chronic lung disease of prematurity (CLDP) or cystic fibrosis | {
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NCT01389024 | 9:34:treatment | Chronic blood transfusion therapy, ongoing or planned | {
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NCT02493530 | 1:17:treatment | Organ transplant recipients | {
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NCT02451423 | ,72:110:treatment | within 2 weeks prior to Cycle 1, Day 1, or anticipated requirement for systemic immunosuppressive medications during the trial | {
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NCT02510456 | 10:20:cancer,33:43:cancer,47:82:cancer,86:103:cancer, | Previous malignancy, other than basal cell or squamous cell carcinoma of the skin or in situ carcinoma of the cervix, from which the patient has been disease free for less than 5 years | {
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NCT02458014 | 40:62:cancer | Active central nervous system (CNS) or extramedullary disease | {
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NCT03042689 | 1:25:chronic_disease | Congestive heart failure | {
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NCT02502006 | 13:33:treatment,,, | received an investigational drug or used an experimental medical device within 30 days prior to screening, or who gave a blood donation of ≥ one pint within 8 weeks prior to screening | {
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NCT03034564 | 1:27:chronic_disease | inflammatory bowel disease | {
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NCT02804906 | 23:56:chronic_disease | Clinical diagnosis of acute myocardial infarction (AMI) | {
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NCT02392286 | 18:40:treatment | Patients in whom corticosteroid therapy is contraindicated | {
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NCT01773694 | 20:44:treatment | patients receiving prophylactic antibiotics | {
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NCT02177838 | ,53:81:treatment,83:107:treatment,161:185:chronic_disease,189:199:chronic_disease, | Patients who have had either myocardial infarction, coronary artery bypass graft, coronary artery stenting, hospital admission for heart related issues such as congestive heart failure or arrhythmia within the last 3 months, will not be allowed on protocol | {
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NCT01245712 | ,37:51:cancer | More than 3 histologically positive axillary nodes | {
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NCT02453113 | 8:25:chronic_disease,27:43:chronic_disease,45:62:chronic_disease,67:80:chronic_disease | Use of systemic steroids, topical steroids, tanning solutions and anticoagulant | {
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NCT02146924 | 41:57:chronic_disease | Research participants with known active hepatitis B or C infection | {
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NCT01429337 | ,,78:89:treatment, | Sexually active males unless they use condom during intercourse while taking midostaurin and for at least 3 months after the last exposure to drug | {
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NCT02213913 | 1:19:treatment | Prior pomalidomide exposure | {
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NCT02706353 | 1:14:treatment | Pembrolizumab such as: condom, diaphragm, hormonal, IUD, or sponge plus spermicide | {
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NCT02564796 | 1:20:chronic_disease | Sickle-cell disease | {
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NCT02593123 | 1:27:cancer | Non-Hodgkin lymphoma (NHL) | {
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NCT03068780 | 1:17:chronic_disease,, | Kindler syndrome aged ≥21 days | {
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NCT02074631 | 22:49:treatment,,91:99:treatment,112:127:treatment,129:138:treatment,143:155:treatment | Prior and/or planned concomitant medical therapy during the study period (through Day 360 post-HCT) with other bisphosphonates, Denosumab, or Teriparatide | {
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NCT02393157 | 53:58:cancer | Patients with newly diagnosed, previously untreated B-NHL | {
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NCT03059888 | 82:87:chronic_disease,89:96:chronic_disease,98:109:chronic_disease,111:127:chronic_disease,129:138:chronic_disease,140:147:chronic_disease,149:159:chronic_disease,163:179:chronic_disease | Subject has the presence at screening of any severe, progressive or uncontrolled renal, hepatic, hematologic, gastrointestinal, pulmonary, cardiac, neurologic or cerebral disease, whether or not related to MG that, in the opinion of the Investigator, might place the subject at unacceptable risk for participation in the study | {
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NCT02296684 | 20:36:chronic_disease,53:77:treatment,,114:124:treatment,158:183:treatment,,225:232:treatment | Has a diagnosis of immunodeficiency or is receiving systemic steroid therapy (in dosing exceeding 10 mg daily of prednisone equivalent) or any other form of immunosuppressive therapy within 7 days prior to the first dose of MK-3475 | {
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NCT02762825 | 1:20:chronic_disease | Atrial fibrillation | {
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NCT02339922 | 1:14:treatment, | Major surgery within 14 days before enrollment | {
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NCT02445222 | 32:41:treatment,51:63:treatment,107:115:treatment,107:135:treatment,159:183:treatment,196:211:treatment | All patients who have received anti-CD19 directed CART therapy and completed or discontinued early from a Novartis sponsored treatment protocol that utilized CD19-directed CART cells or from any CD19 CART trial sponsored by the University of Pennsylvania with which Novartis has a contractual agreement to co-develop the CAR technology | {
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NCT02037048 | 10:30:cancer,35:70:cancer,72:80:cancer,84:119:cancer,125:131:cancer,135:174:cancer | Resected basal cell carcinoma and squamous cell carcinoma of the skin, cervical or prostatic intraepithelial neoplasia, and ductal or lobular carcinoma in situ of the breast | {
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NCT02530073 | 1:21:chronic_disease,, | Diaphragmatic hernia: right-sided or bilateral, major associated anomalies, isolated left-sided with the O/E LHR ≥ 25% | {
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NCT02232516 | 1:31:cancer | T-cell prolymphocytic leukemia | {
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NCT01525901 | 1:20:chronic_disease | renal insufficiency | {
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NCT02875301 | 1:3:chronic_disease | MS | {
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NCT02763033 | 15:41:chronic_disease | Patients with inflammatory bowel disease | {
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NCT00977977 | 1:10:chronic_disease,,,,,, | Cytopenia (neutrophils <1500/mm^3 and/or thrombocytopenia <75,000) and/or CD4 T cell count <200/mm^3) | {
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NCT01042522 | 40:61:cancer,63:83:cancer,85:115:cancer,117:142:cancer,144:157:cancer,160:186:cancer,188:204:cancer,219:241:cancer,243:257:cancer | Patients with histologically confirmed ovarian stromal tumor [granulosa cell tumor, ganulosa cell-theca cell tumor, Sertoli-Leydig cell tumor (androblastoma), steroid (lipid) cell tumor, gynandroblastoma, unclassified sex cord-stromal tumor, sex cord tumor with annular tubules] | {
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NCT02047474 | 1:33:cancer,35:61:cancer,66:96:cancer | basal cell carcinoma of the skin, cervical carcinoma in situ, or non-metastatic prostate cancer | {
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NCT02522715 | 12:19:chronic_disease,110:122:chronic_disease,124:130:chronic_disease,,153:173:cancer,175:191:cancer,193:207:chronic_disease | history of seizure or any condition that may predispose to seizure including, but not limited to, underlying brain injury, stroke in the past 6 months, primary brain tumors, brain metastases, prior seizures | {
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NCT01953588 | 1:28:treatment,42:59:treatment,64:74:treatment, | Hormone replacement therapy of any type, megestrol acetate, or raloxifene within one week prior to registration | {
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NCT02464878 | 1:20:chronic_disease | portal hypertension | {
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NCT02583789 | 23:43:chronic_disease | Patients with primary Raynaud's Phenomenon | {
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NCT03076034 | 16:30:treatment,32:40:treatment,,68:88:treatment,90:100:treatment,102:139:treatment,141:146:treatment | Treatment with bisphosphonate, estrogen (within previous 3 years), teriparatide therapy, calcitonin, selective estrogen receptor modulator (SERMs,within previous 3 years) | {
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NCT02907983 | 11:24:treatment | all other anti-platelet | {
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NCT01140087 | 35:57:treatment | Facial defect or injury requiring facial transplantation as determined by the treating Plastic and Reconstructive Surgeon | {
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NCT02624518 | ,,57:60:treatment | Nadir plus (+) greater than or equal to 2 ng/mL rise in PSA | {
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NCT02939755 | 16:32:chronic_disease,34:43:chronic_disease,55:72:chronic_disease | no evidence of thought disorder, delusions, or active suicidal ideation is observed or reported | {
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NCT01849146 | 66:89:treatment,91:103:treatment,105:118:treatment,122:349:treatment,354:370:treatment,381:392:cancer | going on Arm 1 or combination dose cohort must not have received prior radiation therapy, chemotherapy, immunotherapy or therapy with biologic agent (including immunotoxins, immunoconjugates, antisense, peptide receptor antagonists, interferons, interleukins, tumor infiltrating lymphocytes [TIL], lymphokine-activated killer [LAK] or gene therapy), or hormonal therapy for their brain tumor | {
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NCT02324582 | 11:35:treatment | receiving systemic steroid therapy | {
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