broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-A98990573-003-01-3 | ACH-000650 | IGR37_SKIN | HTS002 | 1 | 1.820349 | -0.024736 | -0.297873 | 1.420808 | 0.637424 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000650 |
BRD-A98990573-003-01-3 | ACH-000748 | SJSA1_BONE | HTS002 | 1 | 1.629373 | -0.022834 | -0.003305 | 1.367757 | 237,882.528641 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000748 |
BRD-A98990573-003-01-3 | ACH-000788 | A2058_SKIN | HTS002 | 1 | 1.556304 | -0.241323 | 0.299702 | 1.227845 | 0.014518 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000788 |
BRD-A98990573-003-01-3 | ACH-000545 | VMCUB1_URINARY_TRACT | HTS002 | 1 | 0.730028 | -2.439885 | -0.209177 | 0.904544 | 0.018865 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000545 |
BRD-A98990573-003-01-3 | ACH-000762 | YD38_UPPER_AERODIGESTIVE_TRACT | HTS002 | 1 | 2.018194 | -0.125205 | -0.058569 | 1.619976 | 2.981759 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000762 |
BRD-A98990573-003-01-3 | ACH-000211 | DAOY_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.830988 | -0.144544 | 0.048558 | 1.327476 | 0.003536 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000211 |
BRD-A98990573-003-01-3 | ACH-000936 | EFO27_OVARY | HTS002 | 1 | 1.838278 | -0.062131 | 0.015137 | 1.364389 | 0.001102 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000936 |
BRD-A98990573-003-01-3 | ACH-000882 | IGR1_SKIN | HTS002 | 1 | 1.783593 | 0.09278 | 0.082606 | 1.267679 | 103.296555 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000882 |
BRD-A98990573-003-01-3 | ACH-000471 | LI7_LIVER | HTS002 | 1 | 1.533157 | 0.505352 | 0.058605 | 1.34906 | 0.012633 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000471 |
BRD-A98990573-003-01-3 | ACH-000670 | SBC5_LUNG | HTS002 | 1 | 1.368531 | -0.258409 | 0.075831 | 1.147542 | 0.013438 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000670 |
BRD-A98990573-003-01-3 | ACH-000048 | TOV112D_OVARY | HTS002 | 1 | 1.550195 | 0.063352 | -0.071279 | 1.321229 | 0.000358 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000048 |
BRD-A98990573-003-01-3 | ACH-000259 | KELLY_AUTONOMIC_GANGLIA | HTS002 | 1 | 1.515884 | -0.109124 | -0.036485 | 1.227478 | 0.008442 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000259 |
BRD-A98990573-003-01-3 | ACH-000599 | PATU8902_PANCREAS | HTS002 | 1 | 1.697333 | -0.0204 | -0.053723 | 1.376231 | 185.683349 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000599 |
BRD-A98990573-003-01-3 | ACH-000716 | TT2609C02_THYROID | HTS002 | 1 | 1.638413 | 0.003429 | -0.008691 | 1.317777 | 1.064217 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000716 |
BRD-A98990573-003-01-3 | ACH-000347 | QGP1_PANCREAS | HTS002 | 1 | 1.566898 | -0.433016 | 0.009184 | 1.14365 | 0.002978 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000347 |
BRD-A98990573-003-01-3 | ACH-000566 | SW1710_URINARY_TRACT | HTS002 | 1 | 1.350184 | 0.069992 | -0.053704 | 1.203651 | 0.000678 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000566 |
BRD-A98990573-003-01-3 | ACH-001016 | BECKER_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.361135 | -0.310624 | 0.065313 | 1.243253 | 1.208025 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-001016 |
BRD-A98990573-003-01-3 | ACH-000395 | NCIH520_LUNG | HTS002 | 1 | 1.436174 | -0.097299 | -0.027539 | 1.256566 | 3.263453 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000395 |
BRD-A98990573-003-01-3 | ACH-000407 | SNU685_ENDOMETRIUM | HTS002 | 1 | 1.945127 | 0.090783 | -0.01996 | 1.492706 | 0.030072 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000407 |
BRD-A98990573-003-01-3 | ACH-000418 | SW1353_BONE | HTS002 | 1 | 3.419838 | -0.114436 | -0.015998 | 2.132578 | 0.024805 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000418 |
BRD-A98990573-003-01-3 | ACH-000008 | A101D_SKIN | HTS002 | 1 | 1.501761 | 0.218633 | 0.006067 | 1.202753 | 0.542737 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000008 |
BRD-A98990573-003-01-3 | ACH-000191 | BHT101_THYROID | HTS002 | 1 | 1.609186 | -0.123199 | -0.075613 | 1.345817 | 0.760553 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000191 |
BRD-A98990573-003-01-3 | ACH-000941 | HEC1B_ENDOMETRIUM | HTS002 | 1 | 1.527177 | -0.042788 | -0.050364 | 1.254625 | 0.015838 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000941 |
BRD-A98990573-003-01-3 | ACH-000532 | SNU61_LARGE_INTESTINE | HTS002 | 1 | 2.091377 | -0.042439 | -0.004104 | 1.576969 | 1.178751 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000532 |
BRD-A98990573-003-01-3 | ACH-000316 | SNU886_LIVER | HTS002 | 1 | 1.593947 | 0.129343 | 0.071052 | 1.254468 | 0.779699 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000316 |
BRD-A98990573-003-01-3 | ACH-000677 | SW1573_LUNG | HTS002 | 1 | 1.67553 | 0.131864 | -0.009404 | 1.256825 | 3.59763 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000677 |
BRD-A98990573-003-01-3 | ACH-000210 | CADOES1_BONE | HTS002 | 1 | 1.448094 | -0.249945 | 0.021653 | 1.091691 | 0.000195 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000210 |
BRD-A98990573-003-01-3 | ACH-000803 | COLO668_LUNG | HTS002 | 1 | 1.765142 | 0.098226 | -0.108707 | 1.511044 | 0.000056 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000803 |
BRD-A98990573-003-01-3 | ACH-000007 | LS513_LARGE_INTESTINE | HTS002 | 1 | 2.04869 | 0.11884 | -0.052451 | 1.43607 | 1.475633 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000007 |
BRD-A98990573-003-01-3 | ACH-000719 | RMGI_OVARY | HTS002 | 1 | 1.231354 | -0.054457 | -0.083873 | 1.194003 | 1,242,980,391,363.15 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000719 |
BRD-A98990573-003-01-3 | ACH-000484 | VMRCRCW_KIDNEY | HTS002 | 1 | 1.545587 | 0.007846 | -0.008949 | 1.271739 | 0.209228 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000484 |
BRD-A98990573-003-01-3 | ACH-000433 | CAKI1_KIDNEY | HTS002 | 1 | 1.830107 | -0.045053 | -0.094601 | 1.387762 | 0.004152 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000433 |
BRD-A98990573-003-01-3 | ACH-000688 | OV7_OVARY | HTS002 | 1 | 2.525953 | 0.029149 | -0.019781 | 1.817195 | 0.000586 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000688 |
BRD-A98990573-003-01-3 | ACH-000603 | BEN_LUNG | HTS002 | 1 | 1.58366 | 0.013974 | 0.008093 | 1.261426 | 248,022.635199 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000603 |
BRD-A98990573-003-01-3 | ACH-000351 | MKN1_STOMACH | HTS002 | 1 | 1.70352 | -0.260435 | 0.05367 | 1.304682 | 0.024315 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000351 |
BRD-A98990573-003-01-3 | ACH-000627 | LCLC103H_LUNG | HTS002 | 1 | 2.170173 | 0.142362 | -0.004723 | 1.250698 | 987.354029 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000627 |
BRD-A98990573-003-01-3 | ACH-000916 | NCIH1573_LUNG | HTS002 | 1 | 2.311052 | 0.006035 | 0.004773 | 1.656346 | 0.051606 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000916 |
BRD-A98990573-003-01-3 | ACH-000863 | DBTRG05MG_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.635168 | 0.069947 | -0.169209 | 1.394398 | 0.000063 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000863 |
BRD-A98990573-003-01-3 | ACH-000066 | HCC4006_LUNG | HTS002 | 1 | 1.322655 | -0.017401 | 0.000458 | 1.173943 | 640.458479 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000066 |
BRD-A98990573-003-01-3 | ACH-000015 | NCIH1581_LUNG | HTS002 | 1 | 1.536849 | 0.165862 | -0.24244 | 1.200193 | 2.112639 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000015 |
BRD-A98990573-003-01-3 | null | null | HTS002 | 1 | 1.713302 | -0.092802 | -0.156442 | 1.371913 | 0.199668 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | false | ACH-000511_FAILED_STR |
BRD-A98990573-003-01-3 | ACH-000674 | NUGC4_STOMACH | HTS002 | 1 | 1.763321 | -0.468645 | 0.649527 | 1.333147 | 0.0365 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000674 |
BRD-A98990573-003-01-3 | ACH-000892 | NCIH1563_LUNG | HTS002 | 1 | 1.081033 | -0.349447 | 0.004121 | 1.014616 | 0.00045 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000892 |
BRD-A98990573-003-01-3 | ACH-000909 | JHUEM2_ENDOMETRIUM | HTS002 | 1 | 1.668088 | 0.299063 | 0.020538 | 1.30189 | 0.166195 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000909 |
BRD-A98990573-003-01-3 | ACH-000237 | JHOM1_OVARY | HTS002 | 1 | 1.619702 | -0.19998 | -0.034923 | 1.323298 | 0.124729 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000237 |
BRD-A98990573-003-01-3 | ACH-000811 | SKOV3_OVARY | HTS002 | 1 | 1.755043 | -0.048146 | -0.048229 | 1.431482 | 31.690909 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000811 |
BRD-A98990573-003-01-3 | ACH-000312 | SKNBE2_AUTONOMIC_GANGLIA | HTS002 | 1 | 1.576632 | -0.076188 | -0.052859 | 1.291012 | 0.100139 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000312 |
BRD-A98990573-003-01-3 | ACH-000901 | HCC1359_LUNG | HTS002 | 1 | 1.907709 | 0.093215 | -0.115198 | 1.278326 | 569.579826 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000901 |
BRD-A98990573-003-01-3 | ACH-000289 | SNU466_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 2.014481 | -0.36223 | -0.038471 | 1.080091 | 0.000029 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000289 |
BRD-A98990573-003-01-3 | ACH-000733 | NCIH1838_LUNG | HTS002 | 1 | 1.855177 | 0.043852 | -0.012144 | 1.500318 | 0.00003 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000733 |
BRD-A98990573-003-01-3 | ACH-000268 | SNU245_BILIARY_TRACT | HTS002 | 1 | 3.019335 | 0.145389 | -0.006777 | 1.601176 | 35.950204 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000268 |
BRD-A98990573-003-01-3 | ACH-000758 | MKN74_STOMACH | HTS002 | 1 | 1.753247 | 0.067618 | -0.117205 | 1.201335 | 264,905.16381 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000758 |
BRD-A98990573-003-01-3 | ACH-000693 | KYSE180_OESOPHAGUS | HTS002 | 1 | 1.433797 | -0.512194 | 0.110691 | 1.376238 | 11.132484 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000693 |
BRD-A98990573-003-01-3 | ACH-000264 | CALU6_LUNG | HTS002 | 1 | 1.490461 | -0.034016 | 0.007249 | 1.271417 | 43.264337 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000264 |
BRD-A98990573-003-01-3 | ACH-000027 | GOS3_CENTRAL_NERVOUS_SYSTEM | HTS002 | 1 | 1.780976 | 0.002659 | -0.008845 | 1.380583 | 15,123,858.959958 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000027 |
BRD-A98990573-003-01-3 | ACH-000720 | TCCSUP_URINARY_TRACT | HTS002 | 1 | 2.198203 | -0.414899 | 0.305273 | 1.387095 | 0.007678 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000720 |
BRD-A98990573-003-01-3 | ACH-000814 | HS939T_SKIN | HTS002 | 1 | 1.089522 | 0.350289 | -0.087846 | 1.073917 | 0.000398 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000814 |
BRD-A98990573-003-01-3 | ACH-000885 | TOV21G_OVARY | HTS002 | 1 | 1.446876 | -0.015603 | -0.097006 | 1.310256 | 5,392,312,553,618,920,000,000 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000885 |
BRD-A98990573-003-01-3 | ACH-000663 | OVTOKO_OVARY | HTS002 | 1 | 1.512865 | 0.023007 | -0.026331 | 1.201196 | 14,546,468.52015 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000663 |
BRD-A98990573-003-01-3 | ACH-000647 | TE1_OESOPHAGUS | HTS002 | 1 | 1.140966 | -0.112351 | -0.167108 | 1.110303 | 8,887.776362 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000647 |
BRD-A98990573-003-01-3 | ACH-000243 | DANG_PANCREAS | HTS002 | 1 | 2.06798 | 0.023153 | -0.05191 | 1.48485 | 228.312576 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000243 |
BRD-A98990573-003-01-3 | ACH-000255 | LMSU_STOMACH | HTS002 | 1 | 1.694342 | -0.174073 | -0.048759 | 1.36352 | 0.138591 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000255 |
BRD-A98990573-003-01-3 | ACH-000335 | MSTO211H_PLEURA | HTS002 | 1 | 1.611948 | 0.242362 | 0.046093 | 1.163893 | 7.613375 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000335 |
BRD-A98990573-003-01-3 | ACH-000147 | T47D_BREAST | HTS002 | 1 | 1.515829 | 0.438492 | 0.221054 | 1.282377 | 0.043484 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000147 |
BRD-A98990573-003-01-3 | ACH-000090 | PC3_PROSTATE | HTS002 | 1 | 1.394236 | 0.025992 | -0.000826 | 1.204897 | 0.003728 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000090 |
BRD-A98990573-003-01-3 | ACH-000171 | VMRCRCZ_KIDNEY | HTS002 | 1 | 2.656364 | 0.187366 | 0.304236 | 1.728065 | 0.311903 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000171 |
BRD-A98990573-003-01-3 | ACH-000614 | RVH421_SKIN | HTS002 | 1 | 1.272173 | -0.052696 | -0.098616 | 1.214494 | 5,870,546,788.39555 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000614 |
BRD-A98990573-003-01-3 | ACH-000132 | JHOS2_OVARY | HTS002 | 1 | 2.230741 | 0.325283 | 0.221803 | 1.396745 | 1.183204 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000132 |
BRD-A98990573-003-01-3 | ACH-000274 | HS852T_SKIN | HTS002 | 1 | 1.47399 | -0.479815 | 0.057247 | 1.142754 | 0.006838 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000274 |
BRD-A98990573-003-01-3 | null | null | HTS002 | 1 | 1.750228 | 0.201317 | -0.000113 | 1.29669 | 0.756598 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | false | ACH-000807_FAILED_STR |
BRD-A98990573-003-01-3 | ACH-000810 | SKMEL30_SKIN | HTS002 | 1 | 2.472409 | -0.199165 | 0.152451 | 1.618257 | 0.01363 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000810 |
BRD-A98990573-003-01-3 | ACH-000022 | PATU8988S_PANCREAS | HTS002 | 1 | 2.849654 | 0.21408 | 0.128675 | 1.579261 | 4.16441 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000022 |
BRD-A98990573-003-01-3 | ACH-000192 | MFE280_ENDOMETRIUM | HTS002 | 1 | 5.776495 | 0.049361 | 0.026225 | 1.556052 | 61,649,147,560,466,696 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000192 |
BRD-A98990573-003-01-3 | null | null | HTS002 | 1 | 1.991773 | -0.127225 | 0.15483 | 1.433521 | 0.010058 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | false | ACH-000409_FAILED_STR |
BRD-A98990573-003-01-3 | ACH-000959 | SNUC4_LARGE_INTESTINE | HTS002 | 1 | 1.58126 | -0.039906 | -0.108018 | 1.260033 | 0.000385 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000959 |
BRD-A98990573-003-01-3 | ACH-000637 | KYSE520_OESOPHAGUS | HTS002 | 1 | 1.806132 | -0.025868 | -0.035974 | 1.388385 | 0.004652 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000637 |
BRD-A98990573-003-01-3 | ACH-000155 | SW1990_PANCREAS | HTS002 | 1 | 1.667241 | -0.126309 | -0.078549 | 1.219068 | 0.000228 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000155 |
BRD-A98990573-003-01-3 | ACH-000605 | TE6_OESOPHAGUS | HTS002 | 1 | 1.692918 | -0.021163 | -0.001809 | 1.372409 | 94.487722 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000605 |
BRD-A98990573-003-01-3 | ACH-000775 | NCIH727_LUNG | HTS002 | 1 | 2.004188 | 0.189041 | 0.000074 | 1.385659 | 1.126313 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000775 |
BRD-A98990573-003-01-3 | ACH-000860 | NCIH358_LUNG | HTS002 | 1 | 1.611675 | -0.116383 | -0.059631 | 1.400415 | 21.867509 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000860 |
BRD-A98990573-003-01-3 | ACH-000994 | HEC59_ENDOMETRIUM | HTS002 | 1 | 1.6132 | 0.005475 | -0.023992 | 1.30062 | 97.074906 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000994 |
BRD-A98990573-003-01-3 | ACH-000277 | HCC1419_BREAST | HTS002 | 1 | 1.817855 | 0.148964 | -0.06611 | 1.400429 | 0.104524 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000277 |
BRD-A98990573-003-01-3 | ACH-000496 | NCIH1792_LUNG | HTS002 | 1 | 2.006292 | 0.107423 | -0.0509 | 1.477566 | 0.205818 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000496 |
BRD-A98990573-003-01-3 | ACH-000866 | NCIH1048_LUNG | HTS002 | 1 | 1.3709 | -0.273824 | -0.014405 | 1.19876 | 0.142358 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000866 |
BRD-A98990573-003-01-3 | ACH-000869 | NCIH1568_LUNG | HTS002 | 1 | 1.999161 | 0.186577 | 0.010162 | 1.442858 | 0.28791 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000869 |
BRD-A98990573-003-01-3 | ACH-000117 | EFM192A_BREAST | HTS002 | 1 | 1.85007 | 0.094906 | -0.05222 | 1.48222 | 0.004288 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000117 |
BRD-A98990573-003-01-3 | ACH-000678 | MKN7_STOMACH | HTS002 | 1 | 1.542258 | -0.042947 | -0.105344 | 1.220461 | 0.000011 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000678 |
BRD-A98990573-003-01-3 | ACH-000493 | SNU423_LIVER | HTS002 | 1 | 1.431697 | -0.012029 | 0.001154 | 1.234876 | 188,865.714916 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000493 |
BRD-A98990573-003-01-3 | ACH-000097 | ZR751_BREAST | HTS002 | 1 | 1.688471 | 1.484038 | 0.091142 | 1.107607 | 2.365127 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000097 |
BRD-A98990573-003-01-3 | ACH-000313 | KMRC3_KIDNEY | HTS002 | 1 | 1.407259 | 0.026586 | -0.000548 | 1.204152 | 0.064402 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000313 |
BRD-A98990573-003-01-3 | ACH-000169 | RD_SOFT_TISSUE | HTS002 | 1 | 1.723997 | -1.182939 | 0.351372 | 1.489127 | 0.438146 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000169 |
BRD-A98990573-003-01-3 | null | null | HTS002 | 1 | 1.402584 | -0.29955 | 0.024625 | 1.257358 | 0.723461 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | false | ACH-000010_FAILED_STR |
BRD-A98990573-003-01-3 | ACH-000841 | NCIH2087_LUNG | HTS002 | 1 | 2.302524 | -0.03314 | -0.024387 | 1.661319 | 0.198809 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000841 |
BRD-A98990573-003-01-3 | ACH-000414 | NCIH1944_LUNG | HTS002 | 1 | 1.430148 | 0.015985 | -0.030223 | 1.226841 | 0.000082 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000414 |
BRD-A98990573-003-01-3 | ACH-000026 | 253JBV_URINARY_TRACT | HTS002 | 1 | 1.590001 | -0.120299 | -0.03823 | 1.265009 | 0.01366 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000026 |
BRD-A98990573-003-01-3 | ACH-000649 | 786O_KIDNEY | HTS002 | 1 | 1.373033 | 0.294751 | 0.092384 | 1.188715 | 0.071175 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000649 |
BRD-A98990573-003-01-3 | ACH-000966 | IGROV1_OVARY | HTS002 | 1 | 1.947296 | -0.238581 | -0.02683 | 1.186921 | 0.000126 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000966 |
BRD-A98990573-003-01-3 | ACH-000958 | SW48_LARGE_INTESTINE | HTS002 | 1 | 3.870752 | 1.502423 | 0.17529 | 1.146091 | 9.385151 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000958 |
BRD-A98990573-003-01-3 | ACH-000270 | HPAC_PANCREAS | HTS002 | 1 | 2.011599 | -0.021576 | -0.008895 | 1.586784 | 251,361.840362 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000270 |
BRD-A98990573-003-01-3 | ACH-000535 | BXPC3_PANCREAS | HTS002 | 1 | 1.964786 | -0.014508 | 0.001158 | 1.67857 | 5,536,578,342,584,630,000,000,000 | null | epinastine | histamine receptor antagonist | ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7 | ophthalmology | conjunctivitis | NC1=NCC2N1c1ccccc1Cc1ccccc21 | Launched | true | ACH-000535 |