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Assistant Professor . . Experienced professional with versatile skills in molecular , computational and structural biology . Competences comprise : Project and team management in interdisciplinary settings Excellent verbal and written communication skills Course planning and execution Consulting and supervision Patent prosecution Budgeting Specialties : Expert in viral infectious diseases High resolution cryo electron microscopy of challenging macromolecular complexes Modeling of molecular structure Molecular dynamics simulations Vaccine design Drug design Bacterial and mammalian cell culturing Protein expression purification RNA transcription purification Bioinformatics AFM on bio molecules Work including radioactive Isotopes Cloning techniques Statistical analysis Software method development and bench marking Data mining and digital signal processing . Technologies : CryoEM

proteins;structure

Computational Biologist . Integrating metagenomics and metabolomics to identify metabolite pathways in microbiomes Developing methodology to automatically identify , score , and analyze synthetic modifications in viruses to determine if a virus is natural or engineered . Computational biology postdoctoral researcher with a focus on developing methodology for transcriptomic , genomic , and microbiome analyses . I work with human clinical , plant , mice , and microbial data across multiple omics layers .. Technologies :

Postdoctoral Associate . Postdoc in the lab of Andew Ward . Structural and biophysical approaches to cryo EM polyclonal epitope mapping EMPEM in the field of HIV vaccine development . . I am a researcher with versatile skills in molecular biology , biochemistry , biophysics , virology and protein chemistry from Dr. Irwin Chaiken Lab at Drexel University College of Medicine . I am also a family chef and enjoy cooking for my family and friends , and connecting with people . Skills : Biophysics surface plasmon resonance SPR Biacore3000 and S200 models , Isothermal Titration Calorimetry ITC , and ELISA . Protein science construct design , subcloning , site directed mutagenesis , PCR , protein expression in bacterial and mammalian expression system HEK293S and HEK293F , protein purification FPLC AKTA pure system with Unicorn 7.2 analysis software IMAC , , protein characterization SDS PAGE , electrophoresis , immunoblotting , analytical gel filtration , spectroscopic assessment . Cell culture techniques E.coli bacterial and mammalian cell culture HEK , CEM lymphoblast and HeLa , transfection , transient expression of proteins , cell based assays colorimetric , fluorometric , flow cytometry . Virology HIV 1 virus production , purification , virus validation , bioassays , virus passaging , inhibitor dose escalation assay . Software Biacore BiaEvaluation , Scrubber 2 , AKTA Unicorn 7.2 , UCSF Chimera v1.14.1 , Pymol , OriginLab , GraphPad Prism 8 , CompuSyn , Image J , MATLAB . . Technologies : CryoEM;ITC;SPR

antibodies;biologics;proteins;developing;interaction;structure

Postdoctoral Researcher . Membrane protein structure and function , primarily using cryo EM methods . . I utilize structural biology methods to investigate membrane protein function Tamir Gonen Lab .. Technologies : CryoEM

membrane proteins;structure

Senior Associate Scientist . . Experienced and enthusiastic research professional with a strong background in structural biology of novel bacterial pathogens , HIV 1 Envelopes , SARS CoV 2 spike , and their antibodies for vaccine design using x ray crystallography , cryo EM , and homology modeling . Demonstrated ability to work hands on , coordinate , and collaborate with experts of diverse backgrounds in structural biology , protein biochemistry , DNA and protein analysis , vaccine design , cell culture , binding analysis , computational biology , and molecular biology . Strong record of public speaking and written communication skills evident by 13 publications , 23 PDB depositions , 15 EMDB depositions , 7 international conference presentations , and 3 awards .. Technologies : Xray;CryoEM

antibodies;proteins;interaction;structure

Technical Support Scientist . I provide technical support by phone and email for customers using Agilent 's automated electrophoresis instruments including the Bioanalyzer , Tapestation , Fragment Analyzer , etc . . I am a young , multi disciplinary biotechnologist with experience in bioinformatics , molecular biology , and biochemistry . A fast learner with a variety of skills from low level programming and data analysis , to cell culture and protein and DNA manipulation . I can fill wetlab roles , drylab roles , or roles requiring comfort in both .. Technologies :

Postdoctoral Scholar . . Postdoctoral researcher in Dr. Daniel Southworth 's lab at the Institute for Neurodegenerative Diseases , UCSF . I am an experienced biophysicist , currently working on studying chaperone protein complexes in Alzheimer 's disease using Cryo EM .. Technologies : CryoEM

idps;structure

Principal Scientist Protein Therapeutics . Responsible for planning and executing multiple analytical and biophysical methods as SPR LSA , HPLC SEC MALS , DSF and other wet lab techniques . As a biophysicist and structural biologist , I have more than five years of experience in the isolation and characterization of soluble and membrane protein , and in my career I have successfully proven management , communication and organization skills as a member of a large research group Prof. Michel , Nobel Laureate and a student supervisor in the Max Planck Institute for Biophysics . In this regard , international scientific stays in renowned places have helped me to constantly improve these characteristics . I am constantly looking forward to apply my strong background in membrane and metallo protein biochemistry as well as my expert knowledge in the implementation of biochemical biophysical methods to an application oriented , creative and international environment .. Technologies : SPR;DSF

membrane proteins;proteins;characterization;interaction

PhD candidate . Knapp Group ; Drug development Development of degrader systems and molecular glues in mammalian cell lines . As a PhD student in the IMI project EUbOPEN and the SGC Frankfurt I am working on cellular systems for development and optimisation of PROTACS and other degraders as well as in crystallography for the identification and optimization of chemical probes and drugs . I strive to use my knowledge of synthetic biology to combine it with current cell biology methods to develop new technologies . Google scholar : https : scholar.google.de citations user jOQsOzoAAAAJ hl de . Technologies :

molecular glues;interaction;structure

Principal Scientist . Protein Homeostasis Centre of Excellence Structural Biology Search for new modalities of targeted protein degradation and stabilization . I am a biochemist structural biologist with a focus on understanding disease associated protein functions through their structures . I am passionate about basic biomedical science research and therapeutics . A visionary with extensive research experience in diverse geographies Asia , Europe and North America over the past 12 years . I am a fast learner , a team player and adapt quickly to new work environments . I have gained extensive research experience in Protein RNA Biochemistry X ray Crystallography and Cryo EM . My expertise include cloning , protein engineering to protein purification , protein crystal structure determination and structure solution . I am experienced in biochemical and biophysical assay development and cell culture . Besides wet lab I am also trained in computer programming and Bioinformatics data analysis derived from proteomics and genomics . I am particularly interested in protein drug interactions and protein protein interaction pathways involved in cellular processes and diseases .. Technologies : Xray;CryoEM

proteins;small molecules;engineering;interaction;structure

Associate Director of Bioinformatics . . I am an enthusiastic and versatile computational scientist and team leader seeking to advance biomedical research . I currently work on the Connectivity Map CMap project , where we have built the world 's largest compendium of gene expression profiles . The goal of CMap is to provide a lookup table for functional annotation of perturbagens and to thereby facilitate the discovery of relationships between drugs , genes , and disease . I also work on the PRISM project where we perform high throughput cell viability screens across hundreds of cancer cell lines , and leverage multi omic cell line characteristics to develop biomarker hypotheses . Specialties : Bioinformatics , Python , R , SQL , Linux , biological research , data collection analysis , team management , excellent communication skills . Technologies :

Principal Research Scientist Group Leader Discovery Biology . I lead a team of research scientists responsible for the hit to lead , and lead to candidate discovery and research phases for veterinary biopharmaceuticals and vaccines . In the therapeutic antibody space , my team is responsible for antibody discovery , species ation , affinity and effector engineering , lead optimization , and cell line generation . In the vaccine space , my team focus on viral reverse genetics , vector design , nucleic acid RNA and DNA vector platforms , and protein antigen engineering . We employ a wide variety of contemporary research techniques including structure based antigen design , antibody engineering , and synthetic biology . Fundamental applications of molecular biology , immunology , cell biology , and protein biochemistry are core to our work . . Group Leader , AH Discovery Biology . Technologies :

antibodies;biologics;carriers;proteins;small molecules;engineering;interaction;screening

Genomic Applications Scientist . . I 'm currently a Genomic Applications Scientist at Oxford Nanopore Technologies , working on exciting long read sequencing applications projects . I 'm also a strong believer in education and promoting knowledge . I enjoy teaching as well as giving public talks . Main topics include algorithms , complexity , software , programming , and bioinformatics .. Technologies :

Research Biochemist . I am a senior scientist in the laboratories of Dr. David Agard and Dr. Nevan Krogan in the Departments of Biochemistry and Biophysics and Cellular and Molecular Pharmacology at UCSF . I study the structure and function of centrosomes , an organelle in mammalian cells that nucleates and organizes microtubules . Microtubules play vital roles in the movement of cargoes throughout the cells , and separating chromosomes when cells divide . I am also a team lead for protein purification in the UCSF Quantitative Biology Institure 's Coronavirus Research Consortium . I am also pursuing high resolution cryo EM structures of BRCA1 complexes important in breast cancer , and have worked on the Tau protein interactome important in neurodegenerative diseases . . I am a senior scientist in the laboratories of Dr. David Agard in the Department of Biochemistry Biophysics and Dr. Nevan Krogan in the Department of Cellular and Molecular Pharmacology at UCSF . We use biochemistry , cell biology , biophysics , mass spectrometry and structural biology cryo EM techniques to understand the structure function relationships of macro molecular machines . I am currently working on several projects : I study the structure and function of the microtubule nucleating machinery in the centrosome . Microtubules play vital roles in the movement of cargoes throughout the cells , and in separating chromosomes when cells divide . The centrioles within centrosomes are necessary for forming cilia . Both centrosomes and centrioles have important implications in human diseases such as cancer and ciliopathies . In response to the SARS CoV2 pandemic , the UCSF Quantitative Biology Institute QBI formed an international consortium QBI Coronavirus Research Group , or QCRG of researchers aimed at understanding how the virus interacts with and co opts processes in human cells . I am working as a protein purification team lead in the structural biology group of QCRG . Our goal is to use cryo electron microscopy and x ray crystallography to solve high resolution structures of viral host protein complexes . http : qbi.ucsf.edu qcrg structuralbiology . As part of the Cancer Cell Map Initiative , I am pursuing high resolution cryo EM structures of BRCA1 containing complexes that are important in breast cancer . I have also worked on the interactome of Tau protein in iPSC derived human neurons by mass spectrometry . Our goal is to understand how Tau protein is involved in neurodegenerative diseases such as Fronto Temporal Dementia and Alzheimer 's . . Technologies : Xray;CryoEM

idps;proteins;interaction;structure

Associate Principal Scientist , Biophysics . . Proactive Biophysicist Dr. rer . nat . with profound expertise in characterising small molecule target interactions fragment based drug discovery lead development , protein protein and protein lipid interactions . Interdisciplinary project management of challenging protein targets and capability development . Mentoring in biophysical fragment screens in drug discovery . . Maintece and application of the following methods : NMR , SPR , TIRF microscopy , confocal microscopy , ITC , FCS , fluorescence spectroscopy , IRRAS , model membrane systems , cytotoxic tests , statistical analysis , biochemistry , microfluidics , clean room class 100 . Biological topics : diverse cancer targets incl small GTPases , neurotransmission synaptic vesicle fusion , amyloids . I enjoy solving problems analytically and am a motivated speaker presenter several poster prizes at international conferences . Additionally , I am able to coordinate and complete projects in a timely and concise manner . I care about data integrity and am consulting collaborators regarding their biophysical setups . . During my international scientific education in renowned labs in Germany , US , France and UK , I have had the opportunity to deepen my experience in scientific communication . I am an active member of the Publication committee of Biophysical journal . As I am eager to bring people together to openly discuss , I have recently organised a workshop Biophysics in Drug Discovery Not just a black box . The purpose of this meeting was to talk about technical issues when using Biophysical methods . It was fully organised but then had to be cancelled due to Covid . It has been postponed to 2022 . In my previous position , I also setup a new seminar series Know your method at the CRUK Beatson Institute teaching about the correct application and publication of diverse methods . During my PhD , I was involved in setting up a conference at the Max Planck Institute New Frontiers in Chemical Biology . I am known to be a proactive person who is eager to help and collaborate . Moreover , I am known to work with integrity and attention to detail on my projects . Data integrity is also very important to me . Therefore , I always try to improve and discuss data with my colleagues . . Technologies : ITC;SPR;NMR

idps;proteins;small molecules;interaction;screening

Scientist II . . . Technologies :

Laborleiterin Spezialistin Proteinbiochemie . Responsibilities : Management and organization of a wet lab of an interdisciplinary research group . Our group aims to develop new solid state NMR techniques on biologically relevant samples to enable structural investigations that crystallography or cryo EM do not provide . My main responsibility is to manage and scientifically supervise the research group members in their daily lab work 1 post doc , 5 PhD students , 1 master student , 1 technical assistant , 1 trainee . I assure the quality of samples and experiments , the implementation and compliance of lab safety regulations , the functionality of lab equipment as well as proper training of lab members . I also significantly participate in the recruitment and selection of new staff members . Beside these responsibilities I develop and optimize expression and purification strategies for different Amyloid peptides a , IAPP , SAA that play a crucial role in certain human diseases Alzheimer s Disease , type II diabetes , amyloidosis . In my current project I investigate the impact of glucose on the oligomerization state of a 42 . . I enjoy working at the interface of structural biology , cell biology and biophysics to gain knowledge of the function of challenging protein complexes . As a passionate wet lab person , I love to devise , realize and optimize experimental strategies and to find the best set of methods to answer scientific questions . My work style is structured , efficient , precise and persistent with distinct analytical skills and an eye for details . In addition , I am a proficient speaker and feel comfortable to present my projects , also in front of big audiences or to explain my work to non experts . As I am managing a multicultural and interdisciplinary research laboratory , I can draw on my excellent communication , organization and staff leadership skills . I am an active listener , a good motivator and like to train people with different educational backgrounds currently chemists and physicists and at different educational levels currently post docs to trainees . Despite the heterogeneity of our research lab members , I succeed to convey the importance of teamwork that now guarantees knowledge exchange , a supportive working atmosphere and smooth work flows . The lab members value me as a quick problem solver for both scientific problems as well as problems concerning the lab organization or equipment . For the first , I profit from my longstanding and extensive research experience . For the latter , my assertiveness , interpersonal and technical skills are a plus . I see need for and would like to apply my skills in the following areas : Research and development Process optimization Method development Quality control quality assurance Lab management Scientific or research services Education training Application support If my profile and skill set matches your requirements , please do not hesitate to contact me . . Technologies : CryoEM;NMR

proteins;structure

Principal Scientist . . Experimental biophysicist interested in protein dynamics .. Technologies :

proteins

Research Associate Biochemistry in Membrane Proteins . Production et purification de r cepteurs coupl s aux Prot ines G RCPG Production et purification de fragments d anticorps en vue de stabiliser le complexe RCPG Prot ines G tude structurale et fonctionnelle de complexes RCPG Prot ines G en cryo EM et SPR Cristallisation de RCPG en phase cubique LCP . Master de Biologie structurale int grative et Bio informatique Facult des Sciences de la vie Universit de Strasbourg . Technologies : CryoEM;SPR

antibodies;membrane proteins;expression;structure

Senior Research Fellow . . A dedicated and enthusiastic antibody engineering scientist with more than 10 years experience in developing antibody based therapeutics . . Technologies :

antibodies;developing;engineering

EIPOD postdoc fellow . Time resolved and in cell cryogenic electron tomography ... no less . Hi , I am an interdisciplinary microscopy engineer with strong interest in methods development for structural biology and neuroscience . After graduating from the research engineering school ESPCI Paris physics , chemistry and biotechnology , I embraced biology with a bridging master Bioengineering Innovation in Neuroscience and a PhD in Neuroscience under the direction of Dr. Triller , in cole Normale Superieure ENS . During my PhD , I have developed 3D correlative light electron microscopy 3D CLEM approaches to quantify the morphological features of identified dendritic spines within intact neuronal circuits . I have set up workflows to combine confocal and super resolutive PALM microscopy with Transmission EM TEM and Serial Block face EM SBEM in brain tissue samples , and I collaborated with a postdoctoral fellow in ENS to constrain a model of signal compartmentalization in dendritic spines with the morphological data I collected https : doi.org 10.1371 journal.pbio.3001375 . I then moved to EMBL Heidelberg in fall 2020 to embrace structural biology and develop high throughput methods for cryogenic electron microscopy cryo EM an imaging approach that can provide native molecular structures with near atomic resolution . Emerging time resolved TR cryo EM technologies aim at capturing and imaging short lived reaction intermediates on cryo EM grids to determine the mechanism of essential biochemical events . Developing new , more robust methods of sample preparation will enable overcoming the intrinsic heterogeneity of TR cryo EM samples . During my stay at EMBL , I also develop workflows to improve the feasibility of cryo electron tomography cryo ET in large cells . My research will provide leverage to interrogate the structural basis of fast biological processes in intact cells . Personally , I have joyful and collaborative temper ; I am patient , rigorous and dedicated to whatever I do . I thrive in international environments and enjoy a culturally rich life wenn m glich . Thanks for reading ; feel free to contact me at olivier.gemin embl.de ; have a nice day and my best regards Olivier Gemin . Technologies : CryoEM

proteins;structure

Senior Computational Scientist . Working in Joshua Levin 's group at the Stanley Center . Involves various projects related to the analysis of NGS data , particularly analyzing single cell RNA Seq data with the hope of better understanding neuropsychiatric diseases . . Computational biologist in the Stanley Center at the Broad Institute , with interests ranging from single cell analysis to privacy preserving genomic analysis .. Technologies :

Senior Scientist . Target Discovery Oncology Integrative Analytics group in the department of Genome and Biomarker Sciences Merck Research Laboratories MRL . . Bioinformatics and Computational Medicine researcher with a successful track record of integration , analysis , visualization , and interpretation of pre clinical and high throuput data . Expert in developing algorithms to apply machine learning , heterogeneous data integration , and , ' omic data and sizeable networks analysis to study complex genetic diseases e.g. , cancer and autoimmune disease , therapeutics response prediction , and computational functional genomics . Over fifteen years of working and presenting in highly multidisciplinary teams of MDs , computational scientists , and biologists . , and , writing articles and grant applications .. Technologies :

Research Fellow . . https : bkellman.github.io Main interests revolve around pediatric diseases , network biology , biostatistics , glycobiology , and metabolomics . Models should be simple and biologically constrained . . Technologies :

Research Technician . Perform routine laboratory maintenance and research activities such as electron microscopy sample processing and imaging , cryo electron microscopy grid screening , cryo sample preparation , negative staining and imaging . Perform administrative duties such as : laboratory management including maintaining reagents , glassware , and routine instrument management tasks ; assisting in record keeping ; and ordering supplies and billing . Provides technical and administrative support for a research project . Collects and enters data . Assists with preparation of manuscripts and other documents . Train and collaborate with incoming graduate students , postdoctoral fellows , and visiting researchers . . . Technologies : CryoEM

proteins;structure

Scientist . . Experienced Scientist with a demonstrated history of working in the hospital health care industry . Strong research professional skilled in Life Sciences , Genomics , Cancer , Molecular Biology , and Sequencing .. Technologies :

Principal Scientist . . 15 years of experience in bioinformatics , genomics , and computational work , with 10 years of analyzing next generation sequencing data and 6 years at industry setting . Built industrial level bioinformatics pipelines in containerized images for analyzing DNA seq , single cell RNA seq , and genotype phenotype data , for both clinical and research purposes . The pipelines can be portable in both cloud computing and on premise systems . Experienced bioinformatician familiar with SAMtools , BWA MEM , GATK , Sentieon , DeepVariant , Parabricks , DRAGEN , STAR , Cell Ranger , PLINK , REGENIE , etc . Established scientific and technical collaboration relationships with strategic partners such as Sentieon and NVIDIA . Developed a Hi C analysis protocol for identifying long range DNA DNA interactions . The protocol handles mapping raw paired end reads , normalizing the data , integrating functional genomics data e.g. ChIP seq , DNase seq , etc . , and categorizing the predicted interacting enhancer promoter pairs .. Technologies :

Vice President , Head of Research . . I seek to improve diseases understanding at the molecular level and apply this knowledge to design , test , and develop novel therapeutics . I am passionate about finding biological problems with clinical applications and apply innovative technologies to bring therapeutics to the clinic . I believe in close partnership between biology and technology to jointly design , execute , and advance projects . I enjoy leading , mentoring , and developing a diverse team of talented scientists with broad areas of expertise including antibody engineering , protein chemistry , biochemistry , immuno oncology , structural as well as computational biology .. Technologies : CryoEM;SLS DLS;SPR;FRET

antibodies;developing;engineering;structure

Associate Director , Computational Drug Discovery . Machine learning , predictive modeling , structural modeling , data science , cheminformatics . Data Science , Artificial Intelligence , Machine Learning , Big Data , Predictive Prescriptive Modeling and Analytics , Scientific Computing , Bioinformatics , R D Informatics , Cheminformatics . Computational chemistry . Computer aided drug design . ADMET modeling . Biophysics . Medicinal chemistry . Biomarkers . Gene expression analysis . Computational protein design .. Technologies :

Senior Bioinformatics Scientist . . G scholar : https : scholar.google.com citations user Suh l7EAAAAJ . Technologies :

Senior Scientist . . Experienced Postdoctoral chemist skilled in peptide synthesis and medicinal chemistry with 2 years research experience working in agriculture industry in Germany . Strong research professional with a Doctor of Philosophy PhD focused in Pharmacology and Peptide Chemistry from University of Auckland . I have experience with a multitude of biochemical and biophysical techniques for evaluating bioactivity and structure of new chemical entities . I am interested in the fast growing field of new modalities for targeting new therapeutic areas .. Technologies :

peptides;proteins;small molecules;characterization;structure

Senior Scientist . Currently working on optimization and upscaling of bacterial pseudomonas fermentation in 2 L , 300 L and 5000 L bioreactor for production of lipopeptides . . Since 2002 , I have been working with yeast molecular genetics and cell biology , protein engineering , enzymology , development of recombinant protein expression systems using bacteria , yeast and mammalian cells as host , bioreactor fermentation , cell culture and facility , assay development GPCRs , enzyme , cell based and ELISA , purification and characterization of enzymes protease and carbohydrase , membrane protein aquaporin and monoclonal antibodies mAbs . With positive attitude , genuine technical interest and curiosity by nature , self motivated and engaged , with outstanding skills in implementation of new methods and technologies as well as further optimization , with demonstrated ability for interdisciplinary work and collaboration . Specific skills : 1 Pilot bioreactor fermentation of microorganisms and mammalian cells for recombinant protein production . 2 Downstream protein enzyme and mAbs purification , process development ultrafiltration diafiltration , IMAC , HIC , size exclusion and IEX chromatography on KTA Unicorn platforms . 3 Random , site directed gene mutagenesis , gene deletion and insertion into yeast genome . 4 Construction of various gene libraries BAC , YAC , phage , cDNA and SAGE library and genomic physical map . 5 Construction of protein expression vector plasmid specifically for bacteria , yeast and mammalian cells . 6 DNA Fingerprinting RFLP , AFLP , PFGE Analysis for genotyping . 7 Mammalian cell culture and stable cell line development using FACS . 8 Construction of DNA encoded combinatorial molecule library for drug discovery . 9 Protein peptide identification by SDS PAGE in gel trypsin digestion and LC MS MS . 10 DNA , vector and protein sequence analysis using vector NTI , SEQtools etc . . 11 NGS next generation sequencing sample preparation and large scale data analysis . 12 Microbial cell analysis under microscope and fluorescence microscope .. Technologies :

antibodies;enzymes;membrane proteins;proteins;engineering;structure

Senior Research Associate . . 4 years professional in Research in Biotechnology , I work as a Research Associate in Drug Discovery at F star for 3 years focusing on the discovery , engineering , and characterisation of complex antibody constructs . Scientific and technically curious mindset with a dynamism approach to research project . Seeking to capitalise on my expertise in a role with the opportunity to lead a project and further develop my skills .. Technologies :

antibodies;characterization;engineering

Researcher PHD Student . Specialising in Cryo EM applications in material science . . . Technologies : CryoEM

Lecturer . T CADD Lectures 2x 45 min Topics 2020 2022 : PROTACs , mRNA and SM inhib . of SARS CoV2 , Cancer Immunotherapy , CAR T cells , Prodrugs Curing HCV Infection , HIV , Fluorine in Medicinal Chemistry , Treatment of Multiple Sclerosis , Treatment of Diabetes FXa inhibitor interrupted case study , All around TNFalpha , Kinase in Signal Transduction BTK ; JAKs TYK2 Inhib . introduction Drug Discovery . . Technologies :

molecular glues;developing

Professor of Computer Science . . Faramarz Valafar is a Professor of Biomedical Informatics , Computer Science , and Joint Doctoral Programs in Epidemiology , Global Health , Electrical and Computer Engineering , and Bioengineering at San Diego State University . He is the founding Director of the Bioinformatics and Medical Informatics Research Center and its associated graduate program . He is the Principal Investigator of the Laboratory for Pathogenesis of Clinical Drug Resistance and Persistence http : tuberculosis.sdsu.edu His areas of expertise lie in Genomics , Epigenetics , and Systems Biology of Infectious Diseases especially Tuberculosis , as well as in data mining and pattern recognition using deep learning , especially in life sciences . He has received several multi year grants from the National Institutes of Health for projects in his area of work including a ten year grant from NIAID to study drug resistance in tuberculosis , as well as contracts from the local industry both as a consultant and as a subcontractor . His recent work includes proteomic , epi genomic , transcriptomic , methylomic , functional genomics of genetic dark matter , and systems biological medical data analysis for drug target identification and design , and functional elucidation of novel genetic proteomic products in drug resistant tuberculosis , cancer diagnosis , reconstruction of gene regulatory networks , prediction of effects of Hydroxyurea on sickle cell anemia patients , and automated structure determination of complex carbohydrates from their NMR and GC EIMS spectra .. Technologies : NMR

Staff Scientist . Comp bio . I am a multidisciplinary scientist with formal training and or research experience in medicine MD , anatomic and clinical pathology residency , artificial intelligence PhD , computer science , molecular biology , and neuroscience . I am passionate about increasing maximal healthspan by engineering novel therapeutics . I spend much of my free time exploring and evaluating the potential of different scientific research and domains .. Technologies :

Staff Scientist , Bioinformatics . . Mentoring and enhancing the computational skills of early career bench scientists and computational biologists enabling them to perform screening analyses . Developing and maintaining bioinformatics tools to analyze functional genomics screening data involving various modalities of CRISPR Cas such as CRISPRko , CRISPRa , CRISPRi and base editing . Developing analysis pipelines for various types of NGS data Developing tools to design and pick efficient guides for genome wide and custom libraries for screening with various existing CRISPR Cas modalities and to test and optimize new CRISPR Cas technologies . Benchmarking in house bioinformatics tools and analysis methods to published methods . Collaborating with software engineering and the operations team to plan and develop tools for teammates and external researchers . Interacting effectively with internal and external researchers from various backgrounds to help them with their computational needs . Presenting concise results of computational analyses to team members and collaborators .. Technologies :

Scientist II , Computational Biology . . . Technologies :

Research Assistant I Computational Biology , Nephrology . . I am a graduate of the University of Rochester and received a B.S. in Data Science with a concentration in Biology and a minor in Japanese . While a student , I gained computational experience in various sectors of biology including evolutionary genomics , clinical cancer research , and software development . When I 'm not debugging code or learning something new , you can find me reading fantasy novels , playing tabletop games , or getting lost in the woods .. Technologies :

Postdoctoral Research Fellow . Working with Professor Karl Deisseroth Neuroscience , Optogenetics . Areas of Expertise : Protein engineering , Computational protein design Rosetta suite , AlphaFold , Membrane proteins , Structural biology including drug binding , Channelrhodopsins , Ion channels , Mammalian protein expression and purification , Electrophysiology neuron and HEK cell patch clamping , Systems neuroscience , Protein biochemistry , Cell signaling , Cloning and Construct Design . . . Technologies :

membrane proteins;small molecules;engineering;interaction;structure

Principal Scientist , Biochemistry , Biophysics Structural biology Lead . . Small molecules drug discovery , hit finding and optimization through structural biology and biophysics . Team and projects supervision . 13 experience in DNA binding proteins , complexes of proteins , membrane proteins enzymes , ion channels , GPCRs , transporters . . Technologies :

membrane proteins;nucleic acids;proteins;small molecules;screening;structure

Senior Director , Bioinformatics . Head the Bioinformatics Group , provide leadership and strategies in Bioinformatics and Computational Biology for all stages of drug development from target discovery to in vitro and in vivo studies to clinical trials to drug approval and post marketing stages with a focus on discovery biological research to help understand various molecular mechanisms especially mechanisms of primary and acquired drug resistance , translational science medicine and molecular and companion diagnostics developments in oncology immuno oncology . Oversee pre clinical molecular data analyses , translational clinical biomarker data analyses and reporting , including preparation of biomarker data packages and reports for submission to regulatory agencies such as FDA and EMA etc . Vice Chair of the Pharmacyclics Science , Technology and Informatics Committee . Member of the Pharmacyclics Biomarker Governance Committee . Member of the Pharmacyclics Information Technology R D Applications Steering Committee . Member of the AbbVie Bioinformatics Steering Committee . Member of the AbbVie Early Development Advisory Committee EDAC for Apoptosis B Cell Signalling Emerging Science . . Subject matter expert and strategic leader in big data advanced analytics and data science with over 25 years of academic industry experiences specialized in statistical genetics genomics , bioinformatics computational biology , biomedical clinical informatics and biostatistics . Track record of high honors and achievements . Served as Grant Reviewer for National Institutes of Health NIH Bioengineering Sciences Technologies : Integrative Analysis for Translational Bioinformatics Section . Served as Grant Reviewer for National Science Foundation NSF Evolutionary Quantitative Genetics Division . Served as National Cancer Institute NCI Designated Developer and Mentor of the Microarray Repository Group in the Integrative Cancer Research Workspace of NCI Cancer Biomedical Informatics Grid caBIG . Served as National Cancer Institute NCI Designated Developer and Mentor of the Informatics for Proteomics Group in the Integrative Cancer Research Workspace of NCI Cancer Biomedical Informatics Grid caBIG . Extensive work experiences in various scientific and therapeutic areas , especially in oncology , immuno oncology , immunology , nutrigenomics , virology infectious diseases .. Technologies :

Research Fellow . . Experienced Research Scientist . Skills : Mathematical Modelling , Numerical Simulation , Computational biology , Data analysis ; Fortran , MATLAB , C , Python , Excel ; Image processing , 3D Reconstruction ; Finite Difference Method , Finite Element Analysis FEA , Parallel Computing ; Biomedical engineering , Electrophysiology , Biomechanics .. Technologies :

Sr Staff Scientist Automation . Automation Assay Development . I lead the automation team within the Assay Development group at Regeneron . My group develops fully automated ELISAs for the testing of preclinical and clinical samples for drug levels and immunogenicity . We have six state of the art integrated Thermo Scientific automation systems with Tecan liquid handlers . Chemiluminescence and MSD Meso Scale Devices are our detection platforms . We use Gemini and Evoware and Polara and Momentum scheduling software . I have written programs to automate and verify anti drug antibody ADA assays on the automation systems . I manage three automation associates . I am the study director for verification of all PK and ADA automated assays . I am responsible for writing SOPs and verification and qualification protocols as per GLP guidelines . My group is also responsible for the maintenance and verification of all lab equipment including readers and washers for the Assay Development and Clinical and Non Clinical Bioanalysis groups . I have 10 years of experience in the development , verification and execution of automated pharmacokinetic PK and immunogenicity ADA assays to support bioanalysis of clinical samples . In addition , I have about 10 years of experience in small molecule drug discovery research specifically in the automation of HTS assays . I have hands on expertise with a wide spectrum of biochemical , cell based and immunological assays and screening techniques , that are transferable between different therapeutic areas including oncology , infections and autoimmune disorders . I also have experience as an application scientist working on hardware and software development for instrumentation . Specialties : Automation of PK ADA assays , Tecan , Polara , ELISA , GLP , Biochemical cellular assay development , High Throughput Screening HTS , SAR analysis , Mode of action assays , enzyme kinetics , application solutions for instrumentations . Technologies :

small molecules;screening

Bioinformatics Scientist Machine Learning . . Bioinformatics Data Scientist Specialties : bioinformatics , genomics , algorithm and methodology design and development , machine learning , deep learning , pattern recognition , data mining , data science , algorithm design , Bayesian and classical statistical inference , statistical and mathematical modeling , big data , regression analysis , classification , clustering , regularizer design , MapReduce , software engineering .. Technologies :

Principal Scientist . . My primary goal is to use any kind of computational methods that help to get the meaningful biological insights and benefit therapeutical pipeline .. Technologies :

Visiting Research Fellow . Investigating exercise in relation to disease prevention and reducing age related complications Overseeing a multi disciplined study including exercise physiology , genomics , and computational biology bioinformatics by investigating cell free DNA and exercise . Skills utilized : set up and manage clinical exercise studies , hired and managed research assistants , analyzed and communicated research results through journal publications , writing manuscripts , writing grants . An exercise biologist who enjoys the science and application . I 'm equally comforatable doing research as a compuational biologist investigating muscle metabolism and training collegiate athletes or the general population . My scientific exepertise is in sports nutrition and exercise biology and metabolism . My clinical expertise is training and developing high school and collegiate athletes and the general populaton . Current Research Focus : Exercise in relation to disease prevention and reducing age related complications . Specialties : Experience with athletic , post rehab , and general populations Expert in muscle energetics and amino acid supplementation . Technologies :

Principal Scientist , Clinical Translational Science . Provide Scientific expertise in Sobi Theuraputic areas and engage in academic collaborations . Currently I work as Principal Scientist in the Clinical Translational Science Department where I provide scientific expertise both to our projects and in evaluation of external projects . I also engage in academic collaborations to advance scientific knowledge in Sobis therapeutic areas . Previously I worked as a Project leader for research Projects and had a scientific lead role in development Projects . I was also involved in protein engineering where I contributed with structure based computational techniques and knowledge on construct design . In my previous role as a senior scientist in computational biology my responsibilies included construct design , regarding fusion partner selection , mutagenesis for selected properties such as solubility , expressability and stability . Specialties : Computational Biology : Protein homology modelling , Sequence based methods , MD simulations , Sequence database administration , Protein protein docking .. Technologies :

Senior Laboratory Research Scientist . . A highly motivated and hard working individual with an impressive range of Biology and Computing skills , including BSc Hons and Ph.D. qualifications in the field of Bioinformatics . An internationally certified Shotokan Karate Instructor , and an internationally certified PADI Open Water Diver . I have a passion for travelling , having spent the last couple of years travelling independently to over 18 countries , including 10 weeks backpacking across India . I am an avid volunteer worker , which has included poverty alleviation in the Dominican Republic as well as working as an unpaid Karate instructor for the last decade . During my mid teens I volunteered at the Wellcome Trust Sanger Institute in Hinxton . I currently work as a bioinformatician at the UCL Cancer Institute , analysing 3C , UMI 4C and Hi C data , with the aim of understanding chromatin structure .. Technologies :

Associate Professor . Research Membrane protein structural biology and teaching PhD MSc undergraduate students , . My main interest is to understand the details of structure function relationship of proteins . In the past i have worked on elucidating structures of protein : protein complexes and enzymes . My current and probably future interest is in the field of membrane proteins , more specifically secondary active transporters , and their role in health and disease .. Technologies :

membrane proteins;structure

Principal Scientist . . A highly skilled , independent and self motivated scientist with interdisciplinary background and excellent communication skills ; 5 Years of pharmaceutical and medical device industry experience in analytical method development and formulation development of small molecule protein peptide nucleic acid based therapeutics , anchored by a strong publication record . TECHNICAL SKILLS : Expertise in analytical method development and qualification for identification , quantitation and impurity profiling of small molecule , protein , peptide and nucleic acid based therapeutics using multiple techniques : Chromatography : HPLC UPLC with UV , RI , CAD , ELSD , MALS and MS detectors for reversed phase , HILIC , SEC , IEX and IP RP based LC separation ; Mass Spectrometry : native MS , ion mobility MS , LC MS MS and ICP MS ; Electrophoresis : CE and cIEF ; Spectroscopy : UV vis , FTIR , fluorescence microscopy , fluorometer , CD and DLS ; Calorimetry : ITC , DSC , TGA and DSF ; Proficient in instrument related software and Python scripting ; Skilled in automated data processing and statistical analysis ; Proficient in pre formulation and formulation development of small molecules and biologics for various dosage forms oral liquid , liposome and polymeric microsphere using QbD and DOE approaches ; Experience in protein purification , protein biophysical assay development and hemostasis assay development ; Experience in regulated GLP and GMP environment ; Excellent communication and technical writing skills ; Strong project management capability in cross functional and multi task environments . Technologies : ITC;SLS DLS;DSC;DSF

biologics;nucleic acids;peptides;proteins;characterization;formulation;interaction

Postdoctoral Researcher . Electron microscopy , CRYO EM , materials science . . Technologies : CryoEM

Staff Scientist , Bioinformatics . . I have several years of research experience encompassing life sciences , mathematics and informatics at premier institutions in collaborative , multidisciplinary environments . While I count informatics and computational skills as my core expertise , my abiding and overarching interest however , remains biology . Over the years I have employed bioinformatics and statistical techniques to make biological sense or facilitate biomarker discovery in RNA Seq , GWAS , Metabolomics and Proteomic datasets . I am fascinated by cloud computing and the AI ML frameworks and continue to build on my expertize in these areas through work and certifications such AWS 's Developer and Big Data speciality certifications and Google 's TensorFlow certification . In my current position at ThermoFisher Scientific , I am spearheading a project that utilizes Next Generation Sequencing as a Quality Control tool to build the next generation of Microarrays .. Technologies :

Application Scientist Research Professor . The Pennsylvania State University Department of Biochemistry and Molecular Biology Assistant Research Professor Galaxy Project https : galaxyproject.org https : usegalaxy.org https : help.galaxyproject.org https : github.com jennaj https : galaxyproject.org people jennifer jackson https : science.psu.edu bmb people jlj22 https : biostar.usegalaxy.org retired archive . Scientist , Manager , Optimist , Innovator . Technologies :

Principal Scientist . Department of Biophysics and Injectable Formulation . Research , Novo Nordisk . I have experience with a broad range of biophysical and biochemical techniques to study peptides , proteins and in particular antibodies , with the primary focus on physical and chemical stability . My interests and project responsibilities have included molecule screening , protein engineering , formulation development , investigation of mode of action , technology development , external collaborations , project management , and patent processes . Currently I work as a principal scientist with focus on biophysics and formulation in early discovery projects .. Technologies :

antibodies;biologics;characterization;engineering;formulation;stability

Computational Biologist . . . Technologies :

Consultant . . Microbiologist with over 9 years experience in Pharma Healthcare related fields . I want to be in a fast paced environment , working with people as part of a team , where I can combine my scientific knowledge , science communication and problem solving skills , gained during my PhD , with my business mindset . Innovation and Leadership Activities : Consulted with department to drive program innovation through data analysis and market research . Seasoned mentor and active team player Marketed the department through social media and managed Microbiology Graduate Program Social Media Team Instagram : UGAMibocrograd , Twitter : UGAMicroGrad , Facebook : UGAMicroGrad Highly skilled in Microsoft 365 Suite , including Teams , Outlook , Forms and OneDrive . Networked with University resources to execute a Sexual Harassment Workshop targeted at STEM graduate students Lobbied for and negotiated improved graduate student health insurance Research Experience and Interests : Microbial physiologist with background in natural product discovery and prokaryotic primary metabolism Active member in graduate community , improving graduate student life , with a focus on communication and transparency Seven years experience with prokaryotic Iron homeostasis Trained in biochemical techniques and instrumentation Proficient in molecular biology techniques . Experience in grant writing 11 semesters of teaching experience Research Techniques : Cryo Electron Microscopy Protein Purification Protein Crystalization Cell Culturing of Streptomyces , Mycobacteria , Staphyloccus , Baccillus species and E. coli HPLC Transmission Electron Microscopy UV vis Spectroscopy Differential Scanning Fluorometry Isothermal Calorimetry Western Blotting Cloning Gibson , PIPE , Traditional . Technologies : CryoEM;ITC

Vice President Research and Early Development . Leadership of the LEO Research unit From target identification to human PoC. Strategy and execution of disease research and drug discovery . New medicines based on small molecule drugs , biologicals and regenerative medicine technologies . Latest activities : Relocation to and operating 6 mth out of Cambridge MA Setting up LEO Rare Disease activities operating out of San Francisco , CA . Drug discovery leadership , Fast to PoC , Immunology , External innovation platforms 20 years with biomedical research 18 years with pharmaceutical R D in the private sector 14 years with management and leadership 200 employees 10 years with portfolio and governance board positions Thorsten 's experience spans broadly across research with significant experience from drug discovery and early drug development . Thorsten 's key expertise sits in immune disorders and inflammatory diseases , especially skin diseases and dermatology , where he also brings business development M A expertise and more recently gained commercial exposure as well . Most of Thorsten 's operations have been conducted out of Copenhagen Denmark but he has a broad network of global collaborators and in 2019 relocated 5 months to Boston Cambridge US to extend his international collaborations . Thorsten and his team has over the years in LEO brought 12 molecules into clinical testing with the most progressed reaching phase 3 . On top 2 new products based on reformulation has been commercialized . Key words are : Target identification and validation Small molecule , antibody drug discovery , regenerative medicine Translational experimental platforms linking biochemistry , preclinical animal models and PoC clinical testing Repositioning , reformulation and life cycle management Business development , R D partnerships and project acquisitions External innovation Rare disease drug development Patent prosecution and patent litigation .. Technologies :

antibodies;biologics;small molecules;developing

Vice Chair . . I 'm a statistician with a focus on medicine , biology , and statistical computing . I have extensive experience in research and analytics for large scale modeling , variable selection methods , and biostatistics . I 'm interested in biologic or medical problems that do n't have an easy or obvious solution . I enjoy teaching , both one on one and classes . Specialties : Proficient : R , SAS , Matlab , LaTeX , high dimensional analytic methodologies , human genetics Competent : Stata , Perl , HTML , CSS , C , Java , cardiology . Technologies :

Associate Scientist BioTD AD Separations and Biochemistry . . Enthusiastic hard working individual currently working in clinical release and stability analytical development . Routinely performs analytical testing using A280 and SoloVPE spectrophotometry and capillary electrophoresis SDS . Competent with software 's including LIMS , Empower , Smart QC and Excel . Schedules weekly team testing in line with business needs . Active member of the 6S team and environmental health and safety team . . Other experiences include a 6 month wet lab research project in the Conway Institute UCD focusing on phage display and discovery of novel antibody fragments against a target antigen . Carried out protein expression in bacterial hosts to obtain the target antigen followed by successive rounds of phage display on immunotubes to isolate antibody fragments from a semi synthetic library . . Previously undertook a 5 month industrial placement as a member of the process optimisation group in TS MS in Eli Lilly and Company . Performed bench scale reactions and in process testing for process validation studies and documentation . This involved organic synthesis in a step by step scaled down reaction which was monitored via HPLC and GC analysis at several stages throughout the process . . Technologies :

stability

Senior Scientist . . Experienced Research Scientist with a demonstrated history of working in the biotechnology industry . Highly skilled in peptide drug design , peptide synthesis and purification , Liquid Chromatography Mass Spectrometry LC MS , protein expression and purification , crystallization and biophysics . Strong professional with project and team coordination experience . . Technologies :

peptides;proteins;characterization;expression;structure

Principal Scientist , Bioanalysis . . PhD Biochemist with over 10 years of experience in early and late stage of drug discovery development in oncology and metabolic diseases using molecular biology , cell biology and protein chemistry techniques Extensive background in cancer biology lung , prostate , lymphoma , multiple myeloma Significant experience in NASH NAFLD Fibrosis Strong leadership quality as demonstrated by independently leading several key drug discovery projects Demonstrated mentoring experience with junior scientists as direct reports to meet the project goals Established track record in successful grant and patent applications Significant experience in designing small molecule screening strategies , executing screening platform , and directing functional studies toward target validation Strong expertise in developing cellular models to understand Mechanism of action MOA in relapsed and refractory disease progression Contribute biomarker identification and validation strategies to build drug discovery programs in the field of targeted oncology with small molecules approach Exceptional oral and written communication skills patent application , SOP writing , technology transfer , journal publications , and conference proceedings Strong interpersonal and problem solving skills with ability to work independently in multi disciplinary teams Working experiences with functional areas of drug development that include biology , medicinal chemistry , and in vivo pharmacology and toxicology Experienced in cell based High Throughput Screening assay method development Working experiences with CROs to design vectors and plasmids or biochemical methods development for enzyme assays Deep understanding of GCP and regulatory protocols and requirement to ensure compliance Highly organized and experienced in working in a fast paced , matrixed , cross functional environment Specialties : Oncology , Biomarker Identification and Validation , Cell Signaling , Cell Based High Throughput Screening Assay , Immunology . Technologies :

small molecules;screening

Senior Scientist Group leader Antibody and Protein Engineering . SECTION : . Biologics Research . ROLES , RESPONSIBILITIES EXPERTISE : . Managing up to 3 Molecular Biology Labs with 8 technicians and responsible for all molecular biology related work packages . Responsible for engineering , humanization of antibodies and bispecific molecules . Successful project leader of cross functional antibody discovery and optimization projects in the indication areas Ophthalmology , Haemophilia , Inflammation and Lung diseases . Leading a cross functional team to establish a bispecific antibody platform including manufacturing , analytics and cell line development . Monitoring the budget of external contracts covering molecular biology related cost centres DNA synthesis , primer , sequencing . Evaluation of external providers for molecular biology related services and implementation in standard processes . . Technologies :

antibodies;proteins;engineering

. . Scientist PhD , In vitro , Biology , Molecular , Pharmacology , Signal transduction , Mechanism of action , Human biology , Medicine , Cell culture , Laboratory , Bioassay , Innovation , Troubleshooting , Documentation , Drug discovery , G protein coupled receptor GPCR , Research , Development , R D , Diabetes , Obesity , Screening , Experiment , Analysis , Pharmaceutical Industry . Technologies :

membrane proteins;developing;screening

Senior Principal Computational Biologist . . I received my PhD degree in the fields of Bioinformatics and Computational biology with strong background in both biology and computer engineering . I have research experiences in various biological problems , including adaptive evolution of haloarchaea , statistical simulation of chemical reaction system , splicing related tumorigenesis , with specialized interest and expertise in genome wide and transcriptome wide analysis of pediatric adult cancer biology and immuno oncology . I also have strong experiences in computational applications including various state of art algorithms , dealing with large scale biological data , especially NGS data including WGS , WES , RNASeq , scRNASeq , Chipseq , ATACseq , WGBS etc . , experience with HPC clusters and being proficient with most popular programming languages , experience in large scale data standardization , integration and data mining .. Technologies :

Member of the Board , Division of Medicinal Chemistry and Chemical Biology . The DMCCB comprises about 750 scientists interested in medicinal chemistry , chemical biology and related fields of research . It organizes scientific events and interacts with other country organizations to represent the Swiss medicinal chemistry and chemical biology community . Co organized the ' Basel Symposium ' 2022 on Intrinsically Disordered Proteins as Drug Targets . . Experienced molecular modeler and computational scientist contributing in a goal oriented and ambitious environment . Started with managing IT infrastructures and developing customer oriented software solutions . Over the last 9 years I have been deeply involved with hands on computer aided drug design projects on lectins , GPCRs , proteases , short chain dehydrogenases , CYP450s , nuclear receptors and microbial enzymes . The skill to explain highly complex matters in an understandable way is what profiles a modeler that excels . . Technologies : Xray;ITC;SPR;NMR

Group leader , Max Planck Institute of Biophysics Frankfurt am Main , Germany . Research focus : Antibody and obody technology , Yeast Display , eukaryotic membrane proteins , G protein coupled receptors , transport proteins , ABC transporter , cryoelectron microscopy . Methods development : Transport assays for ABC transport proteins using fluorescence activated cell sorting FACS , high yield fermentation strategies for methylotrophic yeast Pichia pastoris , scaffold design for obodies . Staff responsibilities : 3 7 PhD students , 2 technical assistants , 1 postdoc . . I am a passionate scientist with a focus on antibody technology and eukaryotic membrane proteins . In addition to my leading position in the laboratory , with the training of Ph . D. and diploma students , in recent years I have worked as a consultant for companies in the biotech industry or as their cooperation partner . The current pandemic has shown how important antibodies can be to fight diseases . Besides conventional antibodies e. g. IgG 's , so called single domain antibodies nanobodies are becoming increasingly important . At the Max Planck Institute of Biophysics , I was able to set up a nanobody platform Yeast Display that allows us to select high affinity nanobodies against membrane and soluble proteins within a few weeks . As recently shown , thanks to these nanobodies , we can now solve structures of small membrane proteins by cryoelectron microscopy . In addition to the classical nanobody formats , I am developing larger scaffolds that can be used for color labeling of target proteins besides their use in structural biology . . I am convinced that in the near future , in addition to research applications , antibodies and their derivatives will play an increasingly important role in the development of biotherapeutics . . My other passion is the research of eukaryotic membrane proteins . These molecules play a crucial role in all aspects of life . Among their important tasks in the cell are communication , production of energy equivalents , enzymatic activities , and the import or export of various substances . Although membrane proteins make up only one third of the human genome , they are targeted by more than 60 of the drugs on the market . Due to their low natural abundance and difficult handling , the structure and function of many of these molecules have not yet been explored . . In addition to G protein coupled receptors and their associated G proteins , I am also interested in eukaryotic transport proteins . These transporters play a major role e. g. , in fighting cancer cells or pathogenic yeasts . Recently , we were able to solve the structure of an ABC B transporter and characterize its transport behavior with different substrates publication submitted . . Technologies : NMR

antibodies;membrane proteins;characterization;structure

Senior Scientist , Biophysics . Siduma Therapeutics is the latest Craig Crews company leveraging its extensive heterobifunctional molecule discovery and development expertise towards a new , disruptive therapeutic platform targeting disease causing proteins . . Senior Scientist , Biophysics , Siduma Therapeutics , Inc. Siduma Therapeutics is the latest Craig Crews company leveraging its extensive heterobifunctional molecule discovery and development expertise towards a new , disruptive therapeutic platform targeting disease causing proteins . Postdoctoral fellowship , Yale University ; PhD in Biophysics , University of Michigan . Two fold research interests in biophysics and structural biology based approaches to characterize molecular bases of macromolecular recognition events , namely protein protein interactions PPIs , and rational design and development of small molecule inhibitors and heterobifunctional small molecule PROTAC ligands against difficult to prosecute pharmacological targets PPIs , transcription factors , epigenetic complexes implicated in human disease .. Technologies : Xray;NMR

molecular glues;proteins;small molecules;interaction;screening

. . I hold a PhD in Molecular Biology from Aarhus University . During my PhD I have studied the structure and function of a protein involved in ciliary transport of membrane proteins . My PhD study has given me extensive knowledge and expertise in molecular cloning , protein expression and purification , biochemistry , and structural biology . In addition , I have a good understanding of many fields of Molecular Biology and I have a strong ability to learn new skills and gain knowledge within new fields . I have a sense of quality and a structured work approach which is beneficial in quality related positions . I am a good listener and throughout my studies I have gained good collaborative skills through internal as well as external collaborations . I am curious as person and I like to expand my knowledge . I am therefore very positive towards new challenges .. Technologies :

membrane proteins;structure

Career Development Fellow . . As a theoretical biologist , I am passionate about evolution and development , but I am also broadly interested and enjoy applying my analytical skills to a variety of research questions and programming problems . Besides doing research , I enjoy learning new skills and teaching .. Technologies :

Lecturer in Bioinformatics . . My background consists of strong programming skills as well as significant training in genomics and molecular biology , which allow me to contribute in multidisciplinary areas such as bioinformatics and computational biology . My research focuses on deriving mechanistic insights through data analysis , integration and interpretation of omics data , with the aim to understand how genetic changes influence gene regulation and affect complex phenotypes . My principal aims at Cardiff University are to identify potential molecular targets for therapeutic intervention in schizophrenia and other psychiatric disorders , in collaboration with Takeda Pharmaceutical Company Limited . At Imeprial College London my principal focus was to investigate the precise mechanisms by which NF B promotes malignant cell survival in Multiple Myeloma and Diffuse Large B Cell Lymphoma and how NF B controls bioenergetic pathways participating in Colon Cancer pathogenesis . During my Ph.D. in Biocomputing group at Sapienza University of Rome , I had the opportunity to analyse several experiments produced by Next Generation Sequencing technologies and to develop specific tools able to improve some critical steps of the analyses , solve problems derived by system complexity and provide user friendly results . I also dealt with different biomedical problems such as the contribution of long non coding RNAs in muscle differentiation , the identification of molecules involved in HBV replications or the generation of a high resolution profile of antigen specific antibody repertoires . Before starting my Ph.D. , I worked for two years in the Department of Biology and Cellular and Molecular Pathology at University of Naples Federico II , where I gained experience in the development and management of biobanks as well as in the design and statistical analysis of observational studies . Meanwhile , I further advanced the work started during my master dissertation on simulating models of gene environment interactions in populations affected by complex diseases . . Technologies :

Senior Staff Scientist . . A computational scientist interested in solving challenging problems at the interface of life science , Chemistry , Physics , and computational sciences . Strong aptitude for public health problems including single molecule biophysics to multiscale modeling , drug discovery delivery , membrane proteins , enzymes , carbohydrates infectious diseases , computational immunology , computational vaccine design ; Specialties : Extensive experience in Computational Biomolecular dynamics , molecular simulation packages Gromacs , NAMD , LAMMPS ; Combining Science and Engineering : Computer aided Design of novel bionanomaterials . High Performance Computing ; cloud computing . Informatics and Analytics : structural Bioinformatics ; NextGen Sequencing , chemical informatics , Data Science .. Technologies :

small molecules;developing

Postdoctoral Research Fellow . Structural characterizations of DNA polymerases . Cryo EM studies of macromolecular complex involved in DNA repair and replication . . . Technologies : CryoEM

nucleic acids;proteins;structure

Sr . Director , Computational Biology . . Currently leading a cross disciplinary team of scientists working to implement , generate and analyze data from state of the art immune profiling technologies in preclinical , translational and clinical space in the field of Immuno oncology . Extensive experience with data generation and analysis of next gen sequencing technologies epigenetics , DNA , RNA for both bulk and single cell , flow cytometry , cyTOF and multiplex Immunohistochemisty IHC Immunoflourescence IF . Computational Biologist by training with significant expertise in development of fit for purpose cross platform analytical methods and solutions aimed at answering biologically relevant questions and hypotheses . Experience in target identification and validation for preclinical research and identification of biomarkers for Translational Medicine programs by integrating large scale molecular and clinical data Specialties : Computational biology bioinformatics , translational research , target discovery and validation , biomarker identification and implementation , data mining , algorithm development , multidimensional data analysis , RNA seq , single cell RNAseq , cyTOF , multiplex IF . Technologies :

Senior Staff Scientist . . Computational biologist with 20 years of research experience in genomics , molecular biology , genetics , epigenetics , bioenergy , plant development , and plant pathology . 10 years of experience in Next Generation Sequencing technologies . Currently supporting product development in the areas of genomics , cancer biology , and infectious disease . Experienced in the development of lab protocols ranging from experimental design to wet lab procedures and analysis pipeline development to enable new methods and new biological insights . Highly interested in combining computational biology , genomic , genetic , and synthetic biology approaches for industrial biotechnology solutions for bioenergy , agriculture , and human health .. Technologies :

Scientific coordinator Project manager Protherwal . Scientific coordination of Protherwal , a research project that brings together with IBA teams from all the French speaking universities of Belgium in radiophysics , physics , biology , chemistry , imaging , and medicine . This project is funded by the Walloon Region . Project manager for the creation of a proton therapy center in Charleroi dedicated to research and patient treatment . . A seasoned project manager and scientist with proven scientific knowledge in clinical and preclinical imaging , with strong experience in strategic and operational management of multidisciplinary projects , highly focused on providing the most tailored and comprehensive services to biotech companies and academic partners . . Offering leadership and expertise in collaboration management , project writing , project planning and budgeting , service pricing , procurement and installation of large high tech equipment . With specific experience in characterizing the therapeutic value of new molecules from peptides and antibody fragments to cell therapy using various imaging approaches , study design , implementation and optimization of clinical and preclinical imaging protocols , image and data analysis , statistics , evaluation and reporting . Guided by values of respect , responsibility , integrity , and scientific rigor , open to innovative ideas and new collaborations . . Technologies :

Principal Scientist II . Chemical Biology Therapeutics Protein Sciences . Lead for membrane protein targets . Driving technology development and structural biology efforts . Drug Discovery Drug Delivery Technologies Molecular Biology Structural Biology Membrane Proteins Transcription Factors Protein Complexes Biophysics Photography . Technologies :

membrane proteins;proteins;screening;structure

Doctoral Researcher . . I am a PhD student at ETH Z rich and Paul Scherrer Institute with experience in structural biology , particularly Cryo electron microscopy , cryo electron tomography , correlative light microscopy , confocal light microscopy FRAP , FRET and biochemistry working mostly with mammalian cell systems . I am particularly interested in cellular signalling and intercellular communication . . Technologies : CryoEM;FRET

proteins;characterization;structure

Principal Scientist Head of X ray crystallography . Continue focus on the structural biology of membrane protein GPCR and GPCR G protein complexes . I am responsible for all X ray crystallography activities in the company , driving multi target collaboration with external clients , managing a team of scientist and the application of serial crystallography at synchrotron and XFEL for drug discovery projects . I am a structural biologist with 15 years industrial experience . I have worked in various pioneering biotechs , and covered research areas including fragment based drug discovery , structure based drug design , membrane protein GPCRs G protein complexes and serial X ray crystallography . Currently responsible for all crystallography activities in the company , driving multi target collaboration projects with external clients and managing a team of scientists . . Specialties : Protein crystallography . Protein engineering . Construct design , expression and purification . Biophysical analysis of protein and protein ligand interaction . Membrane protein GPCR expression , purification and crystallization Lipidic Cubic Phase , bicelle and vapour diffusion approach . GPCR G protein complexes . Serial crystallography . Synchrotron data collection and processing . . Technologies : Xray

membrane proteins;proteins;small molecules;expression;interaction;structure

Senior Research Development Scientist . . I am a scientist , and most of my career has been conducted at the University of Aalborg DK . My current research is focused on interfacing genetically modified proteins with cyclodextrins or cyclodextrin polymers , for the purpose of site directed photo covalent protein immobilization on surfaces or photo labeling of proteins . Genetic engineering is based on the incorporation of non natural amino acids . Particular emphasis is placed on recombinant antibodies scFv . The project is aimed at 1 understanding the fundamental aspects of protein CD interactions ; 2 to develop a method for protein photo coupling to surfaces modified with cyclodextrins or modified cyclodextrins for biosensors and molecular diagnostics . My other research interest is the study of a class of small cytosolic proteins involved in transport and signaling of long chain fatty acids , namely fatty acid binding proteins FABP . The research has been focused on understanding some of the biophysics stability , self aggregation of the brain type , FABP7 , and its function s in glial cell biology . Specialties : Protein chemistry , Protein Recombinant Expression , Gene Technology , Biochemistry , Analytical Chemistry , Spectroscopy , Chromatography , Surface science . Technologies :

antibodies;carriers;engineering;interaction;stability

Postdoc researcher . 1 . Recent postdoc research at UCSF focused on the study of enamel matrix protein self assembly and the protein mediated mineralization processes . Via tissue studies on a transgenic mouse model , we successfully identified unique functional amyloid nanoribbons to be the templates that guide enamel apatite nanofiber formation . In vitro amelogenin nanoribbons were successfully constructed and proved to maintain the ability to guide oriented apatite mineralization . These findings provided deeper insights into the complex enamel formation mechanisms and can also inspire fabricating enamel like materials with advanced mechanical properties . Related studies achieved 2 paradigm shifting research papers 1 first author paper as from the cover publication in The Proceedings of the National Academy of Sciences PNAS . and 2 critical review papers 1 first author as well as a NIH RO1 funding of 3.5 million dollars over 5 years . 2 . Ongoing research focused on pathological biomineralization of renal calculi . Our study provides novel insights into kidney stone formation where the interplay between microbe and host immune response produced an organic network facilitating unwanted stone deposition . The ' double edged sword ' effect of the immune response was demonstrated in pathological biomineralization context for the first time . . Experienced researcher with 6 years of post doctoral training in biochemistry and biomaterials . Development and fulfillment leader of new and existing biochemistry projects with an ability to utilize state of the art technologies for delivering high quality , rigorous results . Diverse research background including protein chemistry , protein engineering , protein assemblies , and protein inorganic interactions . Top down thinker with ability to integrate individual research programs into grander biological context . Strategic decision maker based on thorough and factual information research . Ability to manage project execution with specific steps and detailed planning . Value emotional stability and mental clarity .. Technologies :

idps;proteins;characterization

Senior Research Associate . Biochemical Analysis of antibody products in early CMC . Characterization of antibody candidates with formulation , high concentration and time course stability studies . Assay development and qualification . Analytical techniques UV Vis , HPLC , CE SDS , DLS , Visual Inspection , Viscometry , Biacore SPR . Biochemist MSc currently working on Biochemical analysis of antibody products . Artur graduated with an MSc and BSc in Biochemistry from the University of Porto , Portugal . He has worked in labs studying Neurodegeneration and Cancer , using cell culture , cloning , recombinant protein expression , protein purification , protein QC , cell and protein assays . He 's competent with FPLC systems Akta and Unicorn liquid chromatography techniques ProA , IEX , HIC , SEC , and HPLC Waters UPLC and Empower . keywords : Protein Science , Biotherapeutics , Chromatography .. Technologies : SLS DLS;SPR

antibodies;characterization;formulation;interaction;stability

Chemist . Development and validation of new analytical methods Participate in cross organizational project meetings Transfer of analytical methods to QC and production sites . Highly structured and self motivated analytical chemist with a biophysical background . 5 years of research experience with the biotech industry . Strong background in the development , validation and implementation of bio analytical methods . A proven team player able to work independently . First class problem solving skills . Experienced in design and statistical analysis of experiments . Solid IT knowledge with medium level programming skills . Skills : protein chemistry and stability , enzyme assays and kinetics , mathematical modeling of enzyme kinetics , structure activity relationships , protein purification , chromatography HPLC , IC , assay development and implementation , biosensor technology , biophysical characterization of liposomes and proteins , calorimetry in the biophysical science , electroanalytical chemistry . Technologies :

carriers;enzymes;proteins;characterization;interaction;stability

Doctoral Researcher . My project deals with characterizing SPT6 and its role in RNAPII transcription . For this , I used Auxin Inducible Degron system which achieved acute and targeted depletion of the protein of interest . First , I established AID tagged SPT6 expressing U2OS knockin cell line with CRISPR Cas9 system . Further , we could achieve complete depletion within 4 hrs . Next , we characterised the nascent transcription 4sU seq , DRB 4sU seq , RNAPII occupancy ChIP seq , transcription rate SLAM seq , mathematical modeling , and RNAPII interactome Quantitative MassSpec . That gave us novel insights into function od SPT6 in transcriptional regulation . My working group : Dr. Elmar Wolf : https : www.biozentrum.uni wuerzburg.de molbio research groups ag wolf My other supervisors Prof. Matthias Geyer : http : www.geyer lab.com matthias geyer group leader Prof. Hermann Schindelin : https : www.uni wuerzburg.de rvz forschung forschungsgruppen ag schindelin . I am currently pursuing my PhD at Elmar Wolf 's lab in University of Wuerzburg , Germany . I am interested in understanding the basic RNAPII transcription machinery . We want to understand the role of MYC interacting elongation factors like SPT5 and SPT6 . As transcription is a highly dynamic process , we use acute depletion of protein within 4 6 hours , for studying their direct function . Recently , using AID system for acutely depleting SPT6 , we were able to kinetically differentiate the role SPT6 in RNAPII transcription . Further , I also work on interface of target validation using PROTACs and also , exploring novel transcription factors by screening methods . The key techniques that I use are molecular cloning , CRISPR knockin , targeted protein degradation , basic biochemistry methods , ChIP sequencing , Mass Spectrometry , 4sU sequencing , SLAM seq and basic NGS analysis . I have a keen interest in taking inspiration from nature for everyday solution , or better defined as Biomimicry . Further , apart from quality scientific research , I am keen towards communicating my scientific findings to the general public .. Technologies :

molecular glues;developing;screening;interaction

Machine Learning Researcher . . Specialities : Machine learning , computational biology , computer vision , human computer interaction , gesture and pattern recognition .. Technologies :

Senior Staff Scientist . . Experienced pharmaceutical scientist with broad experience in academic and industry settings . Authored 15 publications including as a corresponding author , 2 patent applications and multiple abstracts at international conferences . Currently managing a team responsible for potency bioassay development as well as for potency and effector function support of preclinical and clinical stage programs . Contributing with technical writing and co authoring of internal reports , regulatory fillings reports post IND and BLA as well as support towards responses to health authority questions . . Technologies : Xray

Clinical Bioinformatics Scientist . . Computational biologist with a broad skill set , a successful track record in bioinformatics and data analysis and over five years of management experience . Self motivated , innovative , quick learning with outstanding communication skills . Excellent ability to collaborate with diverse teams and professionals to develop scientific understanding . Broad experience in next generation sequence data and drug discovery with six years of industry experience . Strong background in molecular biology , chemistry , biochemistry , biophysics and structural biology . Able to see the big pictures with simultaneous strong attention to details . SPECIALTIES : Perl , Python , shell script , Oracle SQL HQL , R , and grid computing . Algorithm and tools development , statistics , computational tools evaluation , data integration , analysis and visualization , data mining and text mining . RNAseq , transcriptomics , proteomics , metagenomics , microbiome , comparative genomics , genomic variant discovery and interpretation , genome sequencing , sequence alignment and genome assembly , genome annotation , database creation curation and maintenance , pathway analysis and interpretation , microarray and gene expression analysis . Team management and project management . PUBLICATION LIST : https : publons.com researcher 3238342 qiandong zeng . Technologies :

Product Informatics Expert . 3rd rotation Manufacturing Science and Technology Data Analytics Supports the development of analytic capabilities in Vaccines manufacturing for data driven decision making Developing a machine learning model that identifies points for optimization in the fermentation process . Configuring an algorithm to provide real time recommendations for yield improvement . . Career Objective : to enable the utilization of big data and data driven decision making in the healthcare industry Computational Tools : Matlab , R , Python , SQL , Git , Spotfire Skills and Experience : project and stakeholder management , management of matrixed teams , development and deployment of pharmacodynamic models , user acceptance testing , problem solving , agile development . Technologies :

Chief Scientific Officer . Leading research across a portfolio of project to identify and develop a range of next generation protein degradation projects . Amphista is advancing a range of completely novel targeted protein degradation TPD mechanisms which address known limitations of current TPD approaches through : i identifying degraders with improved drug like properties , ii broadening the target and cell type scope of degradation and iii reducing resistance potential for degraders used in oncology applications . Discovering new medicines is difficult , I 've spent 20 years doing it so can attest to that . Today though , there are more options , more technologies , more ideas than ever before for helping patients in new ways . There are many unknowns but one thing is certain if we do n't embrace the new ideas and try a few of them , we 're unlikely to succeed building businesses and new therapies using existing dogma . As one of the pioneers of the wave of protein degradation PROTAC therapies now taking the industry by storm , I 'm always interested in learning about new ways to solve old problems and turning ideas into great medicines .. Technologies :

molecular glues;interaction

Associate Director , Computational Biology . . Experienced scientist with a demonstrated history of working in the pharmaceutical and biotech industry . Skilled in Bioinformatics and Data Analysis . Strong research professional with a Doctor of Philosophy Ph.D. focused in Genetics Minor in Statistics from Pennsylvania State University . . Technologies :

Applied Bioinformatics Scientist . Enriched the full length gene consensus repertoire by over 10 folds using a self designed computational algorithm that addresses high error rates in nanopore reads for transgene insertion assay Developed methods that correctly classified 99 of Multiplexed Array Sequencing MAS Seq reads as unusable due to incorrectly sequenced cell barcodes from Deep Mutational Scanning data Achieved a 20 fold increase in off target regions using full length PacBio reads instead of short Illumina reads in AAV gene delivery system Conducted analysis of single cell data from various modalities to better understand the epigenetics of pancreatic neuroendocrine tumors Tested and deployed a novel statistical method to detect mutations from tag based single cell RNA Seq data Incorporated a compendium of computational approaches to predict short repeat regions in the human genome of ALS patients using short read data Interviewed more than 5 candidates for several mid senior to senior roles . Efficient self driven graduate research assistant with success in independent and collaborative research environments . Proven public speaking skills and experienced in presenting at conferences . Highly skilled in conducting research , compiling comprehensive literature reviews and publishing . Passionate bioinformatician with experience in a wide variety of next generation sequencing datasets . Detail oriented and committed to advancing understanding of genomics . Specialities : NGS data processing , Machine learning , Deep learning , Biological databases , Statistical analysis Technologies : Python , R , Java , C , C . Technologies :

Co Founder Managing Director at Heisenware GmbH . . Experienced Senior Software Engineer with a demonstrated history of working in the research industry . Skilled in Research and Development R D , I IoT Architecture , Fullstack Software Development embedded to cloud , Node.js , Python and modern C with a Dr. rer . nat . focused in 3D Cryo Electron Microscopy from Max Planck Institute for Biophysical Chemistry . Author of the open source software VRPC https : vrpc.io .. Technologies : CryoEM

Bioinformatics Scientist III . . There is something about the job I do , is it dopamine rush from solving challenging problems , is it the constant nagging my brain about a problem until a solution clicks , is it the joy of coding to shape an idea into a reality , or is it the ultimate satisfaction of knowing about the work I do might eventually help people out and make their lives healthier . Perhaps , It is the cocktail of above all that keep me motivated and keep me loving my job of Bioinformatician . I have recently moved to Los Angeles , California I have a work permit after working as a Senior Research Scientist and a Global Scientific Consultant in the Bioinformatics team of the R D department at Eone Diagnomics Genome Center EDGC , South Korea . I have been a proud member of EDGC , seeing it grow from being a small start up company to go public , and it gives me immense satisfaction about the part I played in its growth . My job profile at EDGC involved developing pipelines WGS , WES , targeted panels , liquid biopsy , epigenetics related , data analysis , development of algorithms tools , maintenance of the code , documentation , article writing , and guidance to newcomers . I want to emphasize some of the major highlights of my work experiences so far in my carrier . A recent project at EDGC was to develop cancer detection panels of various cancer types using machine learning algorithms on the NGS based epigenetic data . I designed and developed the NGS based epigenetic data analysis pipeline , statistical modeling to identify the cancer specific markers , and implemented machine learning algorithms to identify cancer patient samples . I was involved in developing custom targeted panels for the liquid biopsy based cancer screening and monitoring service . I designed and developed a patient specific DNA markers selection algorithm , primer identification algorithm for the target markers , and pipeline to analyze patient specific custom targeted panel data . I have experience developing NGS analysis related in house tools such as sequence data preprocessing , PCR duplicate removal and error correction , in house variant caller , variant annotator , SNV classifier , etc . Experience with proteomics , molecular dynamics , in silico drug discovery , and scientific writing from my Ph.D. work . Comfortable with Remote Work culture as I remote worked as a global scientific consultant for three months . Now I am actively looking to pour my experience into something meaningful and challenging in Bioinformatics while getting opportunities to learn something new . Let s get connected if our interests align .. Technologies :

Postdoctoral Research Fellow . AFM T l thon Fellowship Application Number : 23210 . Experienced researcher in protein structure analysis and determination . PhD and postdoctoral experience in S o Paulo State University UNESP , Brazil and ENS Paris Saclay France developing experimental structural studies using high performance liquid chromatography , protein crystallography , SAXS , circular dichroism , fluorescence spectroscopy and computational approaches using normal modes and molecular dynamics simulations . I also has teaching experience , working as a professor in high school , technical schools and higher education Sao Paulo State University UNESP Brazil in the disciplines of Biophysics , Radiobiology and Molecular Biology . Currently , I am a postdoctoral researcher at Sorbonne Universit performing the structural characterization of a Kir potassium channel using cryo EM and single particle analysis . . Technologies : Xray;CryoEM;CD

membrane proteins;proteins;characterization;structure

Principal Scientist Lead Discovery . . Biochemist motivated to provide high quality protein reagents , structural and biophysical data to advance drug discovery efforts . Core skills : parallel protein engineering and production , X ray crystallography , cryo EM , biophysical methods structure based analysis . Principal Scientist , Roche , Switzerland 2022 current Senior Scientist , Roche , Switzerland 2019 2022 Postdoctoral Scientist , Genentech , USA 2016 2019 Ph.D. Structural Biology , The University of Queensland , Australia 2012 2015 Research Associate , BioMarin Pharmaceuticals , USA 2011 M.Sc . Eng . Biotechnology , Polytech Marseille , France 2008 2011 M.Sc . Structural Biology , Aix Marseille University , France 2010 2011 . Technologies : Xray;CryoEM

proteins;small molecules;interaction;screening;structure

Chief Pharmacologist VP of Non Clinical Development . . As of 1st January 2019 , I am employed by Galimedix as Chief Pharmacologist VP of Non Clinical Development . My last position at Merz Pharmaceuticals was Principle Scientific Expert Pharmacology in the division R D CNS . At the peak of my managerial responsibilities at Merz I was directly responsible for the department in vitro pharmacology . This group consisted of four full time academic employees and five full time technical assistants . In addition , I directly supervised eight doctoral these s and several postdoctoral academics sandwich students . Techniques mastered used included electrophysiology , molecular biology , biochemistry , protein protein interactions and phenotypic screening . My personal hands on methodological expertise is largely focused on electrophysiological techniques such as whole cell and single channel patch clamp , two electrode voltage clamp , fEPSPs LTP and in vivo single unit recordings . My core academic competence is in the neuropharmacology neurophysiology of ligand gated ion channels and GPCRs with a strong focus on the glutamatergic system , as well as protein protein interactions with a strong focus on ABeta . . Biggest successes include elucidating the unique mechanism of action of memantine 37 papers that aided the registration of this compound for the treatment of Alzheimer s disease and the discovery of novel compounds such as neramexane 10 papers . Specialties : Electrophysiology , phenotypic screeing , repurposing , neuropharmacology , ion channels , GPCRs , protein protein interactions and adipose tissue pharmacology . I have published 92 orginal papers , 23 reviews , 214 conference abstracts , 28 patents . I am an editor reviewer for academic journals and fluent in German . Technologies : SLS DLS;SPR;NMR;FRET

membrane proteins;proteins;interaction

Head of Cryo EM Lab . . . Technologies : CryoEM

structure

Scientist Biophysics . . Research interests include Biophysics , iPS , Organ on a chip , microfluidics , biosensors , protein therapies , drug design , FBLD molecular modeling . . Technologies :

R D Scientist . . Working within R D of clinical flow cytometry to help bring new and exiting products to marked Versatile clinical researcher with practical product development experience within the fields of optical biophysics , exotic fluorescence molecules , bioconjugation , antibodies , nanomedicine , flow cytometry , microscopy , artificial intelligence AI and more . . Technologies :