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import csv
import json
import os
import pandas as pd
import datasets
import sys
import pickle
import subprocess
import shutil
from urllib.request import urlretrieve
from sklearn.model_selection import train_test_split
from sklearn.preprocessing import LabelEncoder
import numpy as np
from tqdm import tqdm
import yaml
_DESCRIPTION = """\
Dataset for mimic4 data, by default for the Mortality task.
Available tasks are: Mortality, Length of Stay, Readmission, Phenotype, Mortality Custom, Length of Stay Custom, Readmission Custom, Phenotype Custom.
The data is extracted from the mimic4 database using this pipeline: 'https://github.com/healthylaife/MIMIC-IV-Data-Pipeline/tree/main'
mimic path should have this form : "path/to/mimic4data/from/username/mimiciv/2.2"
If you choose a Custom task provide a configuration file for the Time series.
"""
_HOMEPAGE = "https://huggingface.co/datasets/thbndi/Mimic4Dataset"
_CITATION = "https://proceedings.mlr.press/v193/gupta22a.html"
_URL = "https://github.com/healthylaife/MIMIC-IV-Data-Pipeline"
_DATA_GEN = 'https://huggingface.co/datasets/thbndi/Mimic4Dataset/resolve/main/data_generation_icu_modify.py'
_DAY_INT= 'https://huggingface.co/datasets/thbndi/Mimic4Dataset/resolve/main/day_intervals_cohort_v22.py'
_COHORT = 'https://huggingface.co/datasets/thbndi/Mimic4Dataset/resolve/main/cohort.py'
_CONFIG_URLS = {'los' : 'https://huggingface.co/datasets/thbndi/Mimic4Dataset/resolve/main/config/los.config',
'mortality' : 'https://huggingface.co/datasets/thbndi/Mimic4Dataset/resolve/main/config/mortality.config',
'phenotype' : 'https://huggingface.co/datasets/thbndi/Mimic4Dataset/resolve/main/config/phenotype.config',
'readmission' : 'https://huggingface.co/datasets/thbndi/Mimic4Dataset/resolve/main/config/readmission.config'
}
def onehot(data,task,feat_cond=False,feat_proc=False,feat_out=False,feat_chart=False,feat_meds=False):
meds=data['Med']
proc = data['Proc']
out = data['Out']
chart = data['Chart']
cond= data['Cond']['fids']
cond_df=pd.DataFrame()
proc_df=pd.DataFrame()
out_df=pd.DataFrame()
chart_df=pd.DataFrame()
meds_df=pd.DataFrame()
#demographic
demo=pd.DataFrame(columns=['Age','gender','ethnicity','label','insurance'])
new_row = {'Age': data['age'], 'gender': data['gender'], 'ethnicity': data['ethnicity'], 'label': data['label'], 'insurance': data['insurance']}
demo = demo.append(new_row, ignore_index=True)
##########COND#########
if (feat_cond):
#get all conds
with open("./data/dict/"+task+"/condVocab", 'rb') as fp:
conDict = pickle.load(fp)
conds=pd.DataFrame(conDict,columns=['COND'])
features=pd.DataFrame(np.zeros([1,len(conds)]),columns=conds['COND'])
#onehot encode
if(cond ==[]):
cond_df=pd.DataFrame(np.zeros([1,len(features)]),columns=features['COND'])
cond_df=cond_df.fillna(0)
else:
cond_df=pd.DataFrame(cond,columns=['COND'])
cond_df['val']=1
cond_df=(cond_df.drop_duplicates()).pivot(columns='COND',values='val').reset_index(drop=True)
cond_df=cond_df.fillna(0)
oneh = cond_df.sum().to_frame().T
combined_df = pd.concat([features,oneh],ignore_index=True).fillna(0)
combined_oneh=combined_df.sum().to_frame().T
cond_df=combined_oneh
##########PROC#########
if (feat_proc):
with open("./data/dict/"+task+"/procVocab", 'rb') as fp:
procDic = pickle.load(fp)
if proc :
feat=proc.keys()
proc_val=[proc[key] for key in feat]
procedures=pd.DataFrame(procDic,columns=['PROC'])
features=pd.DataFrame(np.zeros([1,len(procedures)]),columns=procedures['PROC'])
features.columns=pd.MultiIndex.from_product([["PROC"], features.columns])
procs=pd.DataFrame(columns=feat)
for p,v in zip(feat,proc_val):
procs[p]=v
procs.columns=pd.MultiIndex.from_product([["PROC"], procs.columns])
proc_df = pd.concat([features,procs],ignore_index=True).fillna(0)
else:
procedures=pd.DataFrame(procDic,columns=['PROC'])
features=pd.DataFrame(np.zeros([1,len(procedures)]),columns=procedures['PROC'])
features.columns=pd.MultiIndex.from_product([["PROC"], features.columns])
proc_df=features.fillna(0)
##########OUT#########
if (feat_out):
with open("./data/dict/"+task+"/outVocab", 'rb') as fp:
outDic = pickle.load(fp)
if out :
feat=out.keys()
out_val=[out[key] for key in feat]
outputs=pd.DataFrame(outDic,columns=['OUT'])
features=pd.DataFrame(np.zeros([1,len(outputs)]),columns=outputs['OUT'])
features.columns=pd.MultiIndex.from_product([["OUT"], features.columns])
outs=pd.DataFrame(columns=feat)
for o,v in zip(feat,out_val):
outs[o]=v
outs.columns=pd.MultiIndex.from_product([["OUT"], outs.columns])
out_df = pd.concat([features,outs],ignore_index=True).fillna(0)
else:
outputs=pd.DataFrame(outDic,columns=['OUT'])
features=pd.DataFrame(np.zeros([1,len(outputs)]),columns=outputs['OUT'])
features.columns=pd.MultiIndex.from_product([["OUT"], features.columns])
out_df=features.fillna(0)
##########CHART#########
if (feat_chart):
with open("./data/dict/"+task+"/chartVocab", 'rb') as fp:
chartDic = pickle.load(fp)
if chart:
charts=chart['val']
feat=charts.keys()
chart_val=[charts[key] for key in feat]
charts=pd.DataFrame(chartDic,columns=['CHART'])
features=pd.DataFrame(np.zeros([1,len(charts)]),columns=charts['CHART'])
features.columns=pd.MultiIndex.from_product([["CHART"], features.columns])
chart=pd.DataFrame(columns=feat)
for c,v in zip(feat,chart_val):
chart[c]=v
chart.columns=pd.MultiIndex.from_product([["CHART"], chart.columns])
chart_df = pd.concat([features,chart],ignore_index=True).fillna(0)
else:
charts=pd.DataFrame(chartDic,columns=['CHART'])
features=pd.DataFrame(np.zeros([1,len(charts)]),columns=charts['CHART'])
features.columns=pd.MultiIndex.from_product([["CHART"], features.columns])
chart_df=features.fillna(0)
###MEDS
if (feat_meds):
with open("./data/dict/"+task+"/medVocab", 'rb') as fp:
medDic = pickle.load(fp)
if meds:
feat=meds['signal'].keys()
med_val=[meds['amount'][key] for key in feat]
meds=pd.DataFrame(medDic,columns=['MEDS'])
features=pd.DataFrame(np.zeros([1,len(meds)]),columns=meds['MEDS'])
features.columns=pd.MultiIndex.from_product([["MEDS"], features.columns])
med=pd.DataFrame(columns=feat)
for m,v in zip(feat,med_val):
med[m]=v
med.columns=pd.MultiIndex.from_product([["MEDS"], med.columns])
meds_df = pd.concat([features,med],ignore_index=True).fillna(0)
else:
meds=pd.DataFrame(medDic,columns=['MEDS'])
features=pd.DataFrame(np.zeros([1,len(meds)]),columns=meds['MEDS'])
features.columns=pd.MultiIndex.from_product([["MEDS"], features.columns])
meds_df=features.fillna(0)
dyn_df = pd.concat([meds_df,proc_df,out_df,chart_df], axis=1)
return dyn_df,cond_df,demo
def getXY(dyn,stat,demo,concat_cols,concat):
X_df=pd.DataFrame()
if concat:
dyna=dyn.copy()
dyna.columns=dyna.columns.droplevel(0)
dyna=dyna.to_numpy()
dyna=dyna.reshape(1,-1)
dyn_df=pd.DataFrame(data=dyna,columns=concat_cols)
else:
dyn_df=pd.DataFrame()
for key in dyn.columns.levels[0]:
dyn_temp=dyn[key]
if ((key=="CHART") or (key=="MEDS")):
agg=dyn_temp.aggregate("mean")
agg=agg.reset_index()
else:
agg=dyn_temp.aggregate("max")
agg=agg.reset_index()
if dyn_df.empty:
dyn_df=agg
else:
dyn_df=pd.concat([dyn_df,agg],axis=0)
dyn_df=dyn_df.T
dyn_df.columns = dyn_df.iloc[0]
dyn_df=dyn_df.iloc[1:,:]
X_df=pd.concat([dyn_df,stat],axis=1)
X_df=pd.concat([X_df,demo],axis=1)
return X_df
def encoding(X_data):
gen_encoder = LabelEncoder()
eth_encoder = LabelEncoder()
ins_encoder = LabelEncoder()
gen_encoder.fit(X_data['gender'])
eth_encoder.fit(X_data['ethnicity'])
ins_encoder.fit(X_data['insurance'])
X_data['gender']=gen_encoder.transform(X_data['gender'])
X_data['ethnicity']=eth_encoder.transform(X_data['ethnicity'])
X_data['insurance']=ins_encoder.transform(X_data['insurance'])
return X_data
def generate_split(path,task,concat,feat_cond=True,feat_chart=True,feat_proc=True, feat_meds=True, feat_out=False):
with open(path, 'rb') as fp:
dico = pickle.load(fp)
df = pd.DataFrame.from_dict(dico, orient='index')
X_df=pd.DataFrame()
#y_df=pd.DataFrame(df['label'],columns=['label'])
taskf=task.replace(" ","_")
for _, data in tqdm(df.iterrows(),desc='Encoding Data for '+task+' task'):
concat_cols=[]
sample=data
dyn_df,cond_df,demo=onehot(sample,taskf,feat_cond,feat_chart,feat_proc, feat_meds, feat_out)
dyn=dyn_df.copy()
dyn.columns=dyn.columns.droplevel(0)
cols=dyn.columns
time=dyn.shape[0]
for t in range(time):
cols_t = [str(x) + "_"+str(t) for x in cols]
concat_cols.extend(cols_t)
X= getXY(dyn_df,cond_df,demo,concat_cols,concat)
if X_df.empty:
X_df=pd.concat([X_df,X],axis=1)
else:
X_df = pd.concat([X_df, X], axis=0)
X_df=X_df.fillna(0)
X_df = encoding(X_df)
#X_df=X_df.drop(['label'], axis=1)
return X_df
class Mimic4DatasetConfig(datasets.BuilderConfig):
"""BuilderConfig for Mimic4Dataset."""
def __init__(
self,
**kwargs,
):
super().__init__(**kwargs)
class Mimic4Dataset(datasets.GeneratorBasedBuilder):
VERSION = datasets.Version("1.0.0")
def __init__(self, **kwargs):
self.mimic_path = kwargs.pop("mimic_path", None)
self.encoding = kwargs.pop("encoding",True)
self.config_path = kwargs.pop("config_path",None)
self.test_size = kwargs.pop("test_size",0.2)
self.val_size = kwargs.pop("val_size",0.1)
super().__init__(**kwargs)
BUILDER_CONFIGS = [
Mimic4DatasetConfig(
name="Phenotype",
version=VERSION,
description="Dataset for mimic4 Phenotype task"
),
Mimic4DatasetConfig(
name="Readmission",
version=VERSION,
description="Dataset for mimic4 Readmission task"
),
Mimic4DatasetConfig(
name="Length of Stay",
version=VERSION,
description="Dataset for mimic4 Length of Stay task"
),
Mimic4DatasetConfig(
name="Mortality",
version=VERSION,
description="Dataset for mimic4 Mortality task"
),
Mimic4DatasetConfig(
name="Phenotype Custom",
version=VERSION,
description="Dataset for mimic4 Custom Phenotype task"
),
Mimic4DatasetConfig(
name="Readmission Custom",
version=VERSION,
description="Dataset for mimic4 Custom Readmission task"
),
Mimic4DatasetConfig(
name="Length of Stay Custom",
version=VERSION,
description="Dataset for mimic4 Custom Length of Stay task"
),
Mimic4DatasetConfig(
name="Mortality Custom",
version=VERSION,
description="Dataset for mimic4 Custom Mortality task"
),
]
DEFAULT_CONFIG_NAME = "Mortality"
def map_dtype(self,dtype):
if pd.api.types.is_integer_dtype(dtype):
return datasets.Value('int64')
elif pd.api.types.is_float_dtype(dtype):
return datasets.Value('float64')
elif pd.api.types.is_string_dtype(dtype):
return datasets.Value('string')
else:
raise ValueError(f"Unsupported dtype: {dtype}")
def create_cohort(self):
if self.config.name == 'Phenotype' : self.config_path = _CONFIG_URLS['phenotype']
if self.config.name == 'Readmission' : self.config_path = _CONFIG_URLS['readmission']
if self.config.name == 'Length of Stay' : self.config_path = _CONFIG_URLS['los']
if self.config.name == 'Mortality' : self.config_path = _CONFIG_URLS['mortality']
if self.config.name in ['Phenotype Custom','Readmission Custom','Length of Stay Custom','Mortality Custom'] and self.config.name==None:
raise ValueError('Please provide a config file')
version = self.mimic_path.split('/')[-1]
m = self.mimic_path.split('/')[-2]
s='/'+m+'/'+version
current_directory = os.getcwd()
if os.path.exists(os.path.dirname(current_directory)+'/MIMIC-IV-Data-Pipeline-main'):
dir =os.path.dirname(current_directory)
os.chdir(dir)
else:
#move to parent directory of mimic data
dir = self.mimic_path.replace(s,'')
if dir[-1]!='/':
dir=dir+'/'
elif dir=='':
dir="./"
parent_dir = os.path.dirname(self.mimic_path)
os.chdir(parent_dir)
#clone git repo if doesnt exists
repo_url='https://github.com/healthylaife/MIMIC-IV-Data-Pipeline'
if os.path.exists('MIMIC-IV-Data-Pipeline-main'):
path_bench = './MIMIC-IV-Data-Pipeline-main'
else:
path_bench ='./MIMIC-IV-Data-Pipeline-main'
subprocess.run(["git", "clone", repo_url, path_bench])
os.makedirs(path_bench+'/mimic-iv')
shutil.move(version,path_bench+'/mimic-iv')
os.chdir(path_bench)
self.mimic_path = './mimic-iv/'+version
#download config file if not custom
if self.config_path[0:4] == 'http':
c = self.config_path.split('/')[-1]
file_path, head = urlretrieve(self.config_path,c)
else :
file_path = self.config_path
#create config folder
if not os.path.exists('./config'):
os.makedirs('config')
#save config file in config folder
conf='./config/'+file_path.split('/')[-1]
if not os.path.exists(conf):
shutil.move(file_path,'./config')
#downloads modules from hub
if not os.path.exists('./model/data_generation_icu_modify.py'):
file_path, head = urlretrieve(_DATA_GEN, "data_generation_icu_modify.py")
shutil.move(file_path, './model')
if not os.path.exists('./preprocessing/day_intervals_preproc/day_intervals_cohort_v22.py'):
file_path, head = urlretrieve(_DAY_INT, "day_intervals_cohort_v22.py")
shutil.move(file_path, './preprocessing/day_intervals_preproc')
file_path, head = urlretrieve(_COHORT, "cohort.py")
if not os.path.exists('cohort.py'):
shutil.move(file_path, './')
data_dir = "./data/dict/"+self.config.name.replace(" ","_")+"/dataDic"
sys.path.append(path_bench)
config = self.config_path.split('/')[-1]
script = 'python cohort.py '+ self.config.name.replace(" ","_") +" "+ self.mimic_path+ " "+path_bench+ " "+config
#####################################CHANGE##########
if not os.path.exists(data_dir) :
os.system(script)
#####################################CHANGE##########
config_path='./config/'+config
with open(config_path) as f:
config = yaml.safe_load(f)
feat_cond, feat_chart, feat_proc, feat_meds, feat_out = config['diagnosis'], config['chart'], config['proc'], config['meds'], config['output']
with open(data_dir, 'rb') as fp:
dataDic = pickle.load(fp)
data = pd.DataFrame.from_dict(dataDic)
data=data.T
train_data, test_data = train_test_split(data, test_size=self.test_size, random_state=42)
train_data, val_data = train_test_split(test_data, test_size=self.val_size, random_state=42)
dict_dir = "./data/dict/"+self.config.name.replace(" ","_")
train_dic = train_data.to_dict('index')
test_dic = test_data.to_dict('index')
val_dic = val_data.to_dict('index')
train_path = dict_dir+'/train_data.pkl'
test_path = dict_dir+'/test_data.pkl'
val_path = dict_dir+'/val_data.pkl'
with open(train_path, 'wb') as f:
pickle.dump(train_dic, f)
with open(val_path, 'wb') as f:
pickle.dump(val_dic, f)
with open(test_path, 'wb') as f:
pickle.dump(test_dic, f)
return feat_cond, feat_chart, feat_proc, feat_meds, feat_out, dict_dir
###########################################################RAW##################################################################
def _info_raw(self):
features = datasets.Features(
{
"label": datasets.ClassLabel(num_classes=2,names=["0", "1"]),
"gender": datasets.Value("string"),
"ethnicity": datasets.Value("string"),
"insurance": datasets.Value("string"),
"age": datasets.Value("int32"),
"COND": datasets.Sequence(datasets.Value("string")),
"MEDS": {
"signal":
{
"id": datasets.Sequence(datasets.Value("int32")),
"value": datasets.Sequence(datasets.Sequence(datasets.Value("float32")))
}
,
"rate":
{
"id": datasets.Sequence(datasets.Value("int32")),
"value": datasets.Sequence(datasets.Sequence(datasets.Value("float32")))
}
,
"amount":
{
"id": datasets.Sequence(datasets.Value("int32")),
"value": datasets.Sequence(datasets.Sequence(datasets.Value("float32")))
}
},
"PROC": {
"id": datasets.Sequence(datasets.Value("int32")),
"value": datasets.Sequence(datasets.Sequence(datasets.Value("float32")))
},
"CHART":
{
"signal" : {
"id": datasets.Sequence(datasets.Value("int32")),
"value": datasets.Sequence(datasets.Sequence(datasets.Value("float32")))
},
"val" : {
"id": datasets.Sequence(datasets.Value("int32")),
"value": datasets.Sequence(datasets.Sequence(datasets.Value("float32")))
},
},
"OUT": {
"id": datasets.Sequence(datasets.Value("int32")),
"value": datasets.Sequence(datasets.Sequence(datasets.Value("float32")))
},
}
)
return datasets.DatasetInfo(
description=_DESCRIPTION,
features=features,
homepage=_HOMEPAGE,
citation=_CITATION,
)
def __split_generators_raw(self):
csv_dir = "./data/dict/"+self.config.name.replace(" ","_")
return [
datasets.SplitGenerator(name=datasets.Split.TRAIN, gen_kwargs={"filepath": csv_dir+'/train_data.pkl'}),
datasets.SplitGenerator(name=datasets.Split.VALIDATION, gen_kwargs={"filepath": csv_dir+'/val_data.pkl'}),
datasets.SplitGenerator(name=datasets.Split.TEST, gen_kwargs={"filepath": csv_dir+'/test_data.pkl'}),
]
def _generate_examples_raw(self, filepath):
with open(filepath, 'rb') as fp:
dataDic = pickle.load(fp)
for hid, data in dataDic.items():
proc_features = data['Proc']
chart_features = data['Chart']
meds_features = data['Med']
out_features = data['Out']
cond_features = data['Cond']['fids']
eth= data['ethnicity']
age = data['age']
gender = data['gender']
label = data['label']
insurance=data['insurance']
items = list(proc_features.keys())
values =[proc_features[i] for i in items ]
procs = {"id" : items,
"value": values}
items_outs = list(out_features.keys())
values_outs =[out_features[i] for i in items_outs ]
outs = {"id" : items_outs,
"value": values_outs}
#chart signal
if ('signal' in chart_features):
items_chart_sig = list(chart_features['signal'].keys())
values_chart_sig =[chart_features['signal'][i] for i in items_chart_sig ]
chart_sig = {"id" : items_chart_sig,
"value": values_chart_sig}
else:
chart_sig = {"id" : [],
"value": []}
#chart val
if ('val' in chart_features):
items_chart_val = list(chart_features['val'].keys())
values_chart_val =[chart_features['val'][i] for i in items_chart_val ]
chart_val = {"id" : items_chart_val,
"value": values_chart_val}
else:
chart_val = {"id" : [],
"value": []}
charts = {"signal" : chart_sig,
"val" : chart_val}
#meds signal
if ('signal' in meds_features):
items_meds_sig = list(meds_features['signal'].keys())
values_meds_sig =[meds_features['signal'][i] for i in items_meds_sig ]
meds_sig = {"id" : items_meds_sig,
"value": values_meds_sig}
else:
meds_sig = {"id" : [],
"value": []}
#meds rate
if ('rate' in meds_features):
items_meds_rate = list(meds_features['rate'].keys())
values_meds_rate =[meds_features['rate'][i] for i in items_meds_rate ]
meds_rate = {"id" : items_meds_rate,
"value": values_meds_rate}
else:
meds_rate = {"id" : [],
"value": []}
#meds amount
if ('amount' in meds_features):
items_meds_amount = list(meds_features['amount'].keys())
values_meds_amount =[meds_features['amount'][i] for i in items_meds_amount ]
meds_amount = {"id" : items_meds_amount,
"value": values_meds_amount}
else:
meds_amount = {"id" : [],
"value": []}
meds = {"signal" : meds_sig,
"rate" : meds_rate,
"amount" : meds_amount}
yield int(hid), {
"label" : label,
"gender" : gender,
"ethnicity" : eth,
"insurance" : insurance,
"age" : age,
"COND" : cond_features,
"PROC" : procs,
"CHART" : charts,
"OUT" : outs,
"MEDS" : meds
}
###########################################################ENCODED##################################################################
def _info_encoded(self,X_encoded):
columns = {col: self.map_dtype(X_encoded[col].dtype) for col in X_encoded.columns}
features = datasets.Features(columns)
return datasets.DatasetInfo(
description=_DESCRIPTION,
features=features,
homepage=_HOMEPAGE,
citation=_CITATION,
)
def __split_generators_encoded(self):
data_dir = "./data/dict/"+self.config.name.replace(" ","_")
return [
datasets.SplitGenerator(name=datasets.Split.TRAIN, gen_kwargs={"filepath": data_dir+'/X_train_encoded.csv'}),
datasets.SplitGenerator(name=datasets.Split.VALIDATION, gen_kwargs={"filepath": data_dir+'/X_val_encoded.csv'}),
datasets.SplitGenerator(name=datasets.Split.TEST, gen_kwargs={"filepath": data_dir+'/X_test_encoded.csv'}),
]
def _generate_examples_encoded(self, filepath):
df = pd.read_csv(filepath, header=0)
for i, row in df.iterrows():
yield i, row.to_dict()
#############################################################################################################################
def _info(self):
self.feat_cond, self.feat_chart, self.feat_proc, self.feat_meds, self.feat_out,self.path = self.create_cohort()
if self.encoding :
X_train_encoded=generate_split(self.path+'/train_data.pkl',self.config.name,True,self.feat_cond, self.feat_chart, self.feat_proc, self.feat_meds, self.feat_out)
X_test_encoded=generate_split(self.path+'/test_data.pkl',self.config.name,True,self.feat_cond, self.feat_chart, self.feat_proc, self.feat_meds, self.feat_out)
X_val_encoded=generate_split(self.path+'/val_data.pkl',self.config.name,True,self.feat_cond, self.feat_chart, self.feat_proc, self.feat_meds, self.feat_out)
X_train_encoded.to_csv(self.path+"/X_train_encoded.csv", index=False)
X_test_encoded.to_csv(self.path+"/X_test_encoded.csv", index=False)
X_val_encoded.to_csv(self.path+"/X_val_encoded.csv", index=False)
return self._info_encoded(X_train_encoded)
else:
return self._info_raw()
def _split_generators(self, dl_manager):
if self.encoding :
return self.__split_generators_encoded()
else:
return self.__split_generators_raw()
def _generate_examples(self, filepath):
if not self.encoding :
yield from self._generate_examples_raw(filepath)
else:
yield from self._generate_examples_encoded(filepath)
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